# emapper version: emapper-2.0.1 emapper DB: 2.0
# command: ./emapper.py  -m diamond --seed_ortholog_evalue 0.00001 --data_dir /home/bayegy/Databases/emapper/data_dir2.0.1/ --cpu 30 --temp_dir /media/bayegy/disk2/bayegy/pipeline_demos/binning/share2/Bin_all/emapper//MAG.T21.45/_tmp -i /media/bayegy/disk2/bayegy/pipeline_demos/binning/share2/Bin_all/Bin_prokka//MAG.T21.45/MAG.T21.45.faa -o /media/bayegy/disk2/bayegy/pipeline_demos/binning/share2/Bin_all/emapper//MAG.T21.45/MAG.T21.45 --usemem --override
# time: Wed Feb 25 22:56:55 2026
#query_name	seed_eggNOG_ortholog	seed_ortholog_evalue	seed_ortholog_score	best_tax_level	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	taxonomic scope	eggNOG OGs	best eggNOG OG	COG Functional cat.	eggNOG free text desc.
MAG.T21.45_00001	1086011.HJ01_02409	1.3e-108	399.4	Flavobacterium													Bacteria	1IHMB@117743,28HAW@1,2NW7D@237,2Z7N4@2,4NG29@976	NA|NA|NA	S	KilA-N
MAG.T21.45_00002	761193.Runsl_0515	4.7e-120	437.6	Cytophagia													Bacteria	47JTM@768503,4NDYY@976,COG2207@1,COG2207@2	NA|NA|NA	K	helix_turn_helix, arabinose operon control protein
MAG.T21.45_00003	761193.Runsl_0514	3.3e-93	348.2	Cytophagia													Bacteria	2CJWE@1,30Y1E@2,47N1F@768503,4NNQQ@976	NA|NA|NA		
MAG.T21.45_00004	1123057.P872_15230	3.9e-51	207.6	Cytophagia				ko:K09931					ko00000				Bacteria	47PJJ@768503,4NGG3@976,COG1216@1,COG1216@2	NA|NA|NA	S	Glycosyl transferase, family 2
MAG.T21.45_00005	1189612.A33Q_3858	7.4e-142	510.0	Cytophagia	fic			ko:K04095					ko00000,ko03036				Bacteria	47SYE@768503,4NID4@976,COG2184@1,COG2184@2	NA|NA|NA	D	Fic/DOC family
MAG.T21.45_00007	1286093.C266_17591	2.3e-147	529.3	Burkholderiaceae	arsA		3.6.3.16	ko:K01551					ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1			Bacteria	1K4KH@119060,1MUTX@1224,2VK65@28216,COG0003@1,COG0003@2	NA|NA|NA	P	Arsenite-activated ATPase (ArsA)
MAG.T21.45_00008	760192.Halhy_6792	0.0	1576.2	Bacteroidetes													Bacteria	4PN1Z@976,COG3748@1,COG3748@2	NA|NA|NA	S	Protein of unknown function (DUF1549)
MAG.T21.45_00009	760192.Halhy_6791	4.3e-248	863.6	Sphingobacteriia													Bacteria	1J0X0@117747,4PKKW@976,COG3119@1,COG3119@2	NA|NA|NA	P	Protein of unknown function (DUF1501)
MAG.T21.45_00010	760192.Halhy_6790	1e-106	394.0	Sphingobacteriia													Bacteria	1IPVN@117747,4NFES@976,COG4886@1,COG4886@2	NA|NA|NA	S	Planctomycete cytochrome C
MAG.T21.45_00011	929562.Emtol_4032	8.9e-159	566.6	Cytophagia													Bacteria	47MH2@768503,4NIJX@976,COG4409@1,COG4409@2	NA|NA|NA	G	BNR repeat-like domain
MAG.T21.45_00012	471854.Dfer_3218	2e-156	558.9	Cytophagia													Bacteria	47N67@768503,4NHGJ@976,COG3356@1,COG3356@2	NA|NA|NA	S	PFAM Neutral alkaline nonlysosomal ceramidase
MAG.T21.45_00013	525373.HMPREF0766_11688	1.5e-148	532.7	Sphingobacteriia													Bacteria	1IQMA@117747,4NES6@976,COG2855@1,COG2855@2	NA|NA|NA	S	PFAM Uncharacterised protein family UPF0324
MAG.T21.45_00014	1202532.FF52_00670	1.3e-41	176.0	Flavobacterium													Bacteria	1IJDA@117743,2BVIP@1,2NW7G@237,32QWT@2,4PKQQ@976	NA|NA|NA		
MAG.T21.45_00015	1121897.AUGO01000003_gene1705	1.6e-51	209.1	Flavobacterium	paiA	GO:0003674,GO:0003824,GO:0004145,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0043937,GO:0043939,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0050793,GO:0051093,GO:0065007	2.3.1.57	ko:K22441					ko00000,ko01000				Bacteria	1I26T@117743,2NW1A@237,4NP1E@976,COG0454@1,COG0456@2	NA|NA|NA	K	Acetyltransferase (GNAT) domain
MAG.T21.45_00016	1239962.C943_02984	9.4e-51	206.1	Cytophagia				ko:K09966					ko00000				Bacteria	47QRD@768503,4NQDE@976,COG3651@1,COG3651@2	NA|NA|NA	S	Uncharacterized protein conserved in bacteria (DUF2237)
MAG.T21.45_00017	929703.KE386491_gene1682	7.5e-30	137.1	Cytophagia													Bacteria	47XV6@768503,4NU9W@976,COG1670@1,COG1670@2	NA|NA|NA	J	Acetyltransferase (GNAT) domain
MAG.T21.45_00018	755732.Fluta_3957	1.3e-90	340.5	Cryomorphaceae				ko:K06889					ko00000				Bacteria	1HWSK@117743,2PB56@246874,4NFRN@976,COG1073@1,COG1073@2,COG1506@1,COG1506@2	NA|NA|NA	E	Serine aminopeptidase, S33
MAG.T21.45_00019	1121481.AUAS01000002_gene3324	7.2e-34	150.2	Cytophagia													Bacteria	47QIX@768503,4NE70@976,COG3865@1,COG3865@2	NA|NA|NA	S	3-demethylubiquinone-9 3-methyltransferase
MAG.T21.45_00020	1234664.AMRO01000027_gene1215	1.9e-20	105.5	Geobacillus													Bacteria	1V9WC@1239,1WHEF@129337,2AFVE@1,315XY@2,4HJ2Y@91061	NA|NA|NA		
MAG.T21.45_00021	1288963.ADIS_2428	2.7e-215	754.6	Cytophagia													Bacteria	47KJR@768503,4NHDZ@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_00022	866536.Belba_3086	5.9e-14	83.2	Bacteroidetes													Bacteria	2ERUU@1,33JE1@2,4NZ11@976	NA|NA|NA		
MAG.T21.45_00023	1120951.AUBG01000001_gene1042	8.4e-18	96.3	Bacteroidetes													Bacteria	4NXUR@976,COG3668@1,COG3668@2	NA|NA|NA	S	Plasmid stabilization system
MAG.T21.45_00024	760192.Halhy_4428	9.1e-204	716.5	Sphingobacteriia		GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464											Bacteria	1IZBN@117747,4P662@976,COG1233@1,COG1233@2	NA|NA|NA	Q	Flavin containing amine oxidoreductase
MAG.T21.45_00025	421072.IO89_15725	8.6e-303	1047.0	Chryseobacterium													Bacteria	1HY5G@117743,3HIMX@358033,4NF2S@976,COG1061@1,COG1061@2,COG1112@1,COG1112@2	NA|NA|NA	KL	Protein of unknown function (DUF4011)
MAG.T21.45_00026	616991.JPOO01000003_gene2358	3.3e-39	169.5	Flavobacteriia													Bacteria	1HZEG@117743,4NFES@976,COG4886@1,COG4886@2	NA|NA|NA	S	Planctomycete cytochrome C
MAG.T21.45_00027	616991.JPOO01000003_gene2360	2.2e-215	755.0	Arenibacter													Bacteria	1I00J@117743,23HRP@178469,4NE73@976,COG4102@1,COG4102@2	NA|NA|NA	S	Protein of unknown function (DUF1501)
MAG.T21.45_00028	616991.JPOO01000003_gene2361	6.5e-304	1050.0	Flavobacteriia													Bacteria	1I81J@117743,4NJ8T@976,COG2010@1,COG2010@2	NA|NA|NA	C	Protein of unknown function (DUF1549)
MAG.T21.45_00029	760192.Halhy_1300	0.0	1424.1	Bacteroidetes													Bacteria	4NKGP@976,COG2010@1,COG2010@2,COG2133@1,COG2133@2	NA|NA|NA	C	Cytochrome c
MAG.T21.45_00030	1121104.AQXH01000001_gene1272	3.3e-53	215.7	Sphingobacteriia			3.4.16.4	ko:K01286					ko00000,ko01000				Bacteria	1IXNE@117747,4NNBR@976,COG1680@1,COG1680@2	NA|NA|NA	V	Beta-lactamase
MAG.T21.45_00031	760192.Halhy_0759	2.8e-71	275.4	Bacteria													Bacteria	COG2207@1,COG2207@2	NA|NA|NA	K	Transcriptional regulator
MAG.T21.45_00032	760192.Halhy_0760	6.3e-35	153.3	Sphingobacteriia													Bacteria	1IZ3F@117747,298PG@1,2ZVTY@2,4PJH3@976	NA|NA|NA		
MAG.T21.45_00033	760192.Halhy_0178	2.9e-60	238.8	Sphingobacteriia	vdlC												Bacteria	1IY1K@117747,4NGKR@976,COG4221@1,COG4221@2	NA|NA|NA	S	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAG.T21.45_00034	760192.Halhy_5864	1.2e-124	453.0	Sphingobacteriia	corA			ko:K03284					ko00000,ko02000	1.A.35.1,1.A.35.3			Bacteria	1IWM4@117747,4NGM7@976,COG0598@1,COG0598@2	NA|NA|NA	P	Mg2 transporter protein, CorA family protein
MAG.T21.45_00035	760192.Halhy_5859	1.8e-125	456.1	Sphingobacteriia	lolE_1			ko:K09808	ko02010,map02010	M00255			ko00000,ko00001,ko00002,ko02000	3.A.1.125			Bacteria	1IPU4@117747,4NFWZ@976,COG4591@1,COG4591@2	NA|NA|NA	M	ABC-type transport system involved in lipoprotein release permease component
MAG.T21.45_00036	504487.JCM19302_3544	2.5e-22	114.8	Flavobacteriia													Bacteria	1HZEZ@117743,4P0IA@976,COG0745@1,COG0745@2,COG3292@1,COG3292@2,COG5002@1,COG5002@2	NA|NA|NA	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MAG.T21.45_00037	1121007.AUML01000019_gene726	2.5e-20	105.9	Aquimarina				ko:K07705	ko02020,map02020	M00492			ko00000,ko00001,ko00002,ko02022				Bacteria	1I0BK@117743,2YK27@290174,4NKXC@976,COG3279@1,COG3279@2	NA|NA|NA	KT	LytTr DNA-binding domain
MAG.T21.45_00038	760192.Halhy_5793	1.2e-156	559.7	Sphingobacteriia	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	1IPGT@117747,4NF19@976,COG0162@1,COG0162@2	NA|NA|NA	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MAG.T21.45_00039	1122176.KB903554_gene3927	1.1e-83	316.6	Sphingobacteriia	trpA		4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQ26@117747,4NE21@976,COG0159@1,COG0159@2	NA|NA|NA	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MAG.T21.45_00040	760192.Halhy_4990	1.6e-176	625.5	Sphingobacteriia	trpB	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000				Bacteria	1IP5T@117747,4NDWP@976,COG0133@1,COG0133@2	NA|NA|NA	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MAG.T21.45_00041	760192.Halhy_4991	1.6e-43	183.0	Sphingobacteriia	trpF	GO:0000162,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48,4.2.1.160,4.2.1.20,5.3.1.24	ko:K01696,ko:K01817,ko:K13498,ko:K22100	ko00260,ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map00790,map01100,map01110,map01130,map01230	M00023,M00840	R00674,R02340,R02722,R03508,R03509,R11072	RC00209,RC00210,RC00700,RC00701,RC00944,RC00945,RC02868,RC03343	ko00000,ko00001,ko00002,ko01000			iJN678.trpF,iPC815.YPO2205,iSBO_1134.SBO_1804,iSDY_1059.SDY_1330	Bacteria	1IS9C@117747,4NNQ1@976,COG0135@1,COG0135@2	NA|NA|NA	E	Belongs to the TrpF family
MAG.T21.45_00042	485918.Cpin_1825	5.6e-67	261.2	Sphingobacteriia	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPVG@117747,4NFJT@976,COG0134@1,COG0134@2	NA|NA|NA	E	Belongs to the TrpC family
MAG.T21.45_00043	760192.Halhy_4993	2.3e-128	465.3	Sphingobacteriia	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000				Bacteria	1INY5@117747,4NH2J@976,COG0547@1,COG0547@2	NA|NA|NA	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MAG.T21.45_00044	1122176.KB903554_gene3932	1.1e-61	243.0	Sphingobacteriia	trpG		2.4.2.18,2.6.1.85,4.1.3.27	ko:K01658,ko:K01664,ko:K13497	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01073,R01716	RC00010,RC00440,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000				Bacteria	1ISHY@117747,4NE4I@976,COG0512@1,COG0512@2	NA|NA|NA	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase
MAG.T21.45_00045	760192.Halhy_4995	2.2e-183	648.7	Sphingobacteriia	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQIH@117747,4NFQ5@976,COG0147@1,COG0147@2	NA|NA|NA	EH	Anthranilate synthase
MAG.T21.45_00046	760192.Halhy_0296	1.8e-91	342.8	Sphingobacteriia	holA		2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1IQ3N@117747,4NEIB@976,COG1466@1,COG1466@2	NA|NA|NA	L	DNA polymerase III delta subunit
MAG.T21.45_00047	1122176.KB903531_gene2999	1.6e-132	479.2	Sphingobacteriia	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQ8D@117747,4NE83@976,COG0276@1,COG0276@2	NA|NA|NA	H	Catalyzes the ferrous insertion into protoporphyrin IX
MAG.T21.45_00048	760192.Halhy_5066	3.2e-101	374.8	Sphingobacteriia	surE		3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110		R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000				Bacteria	1IP3M@117747,4NEJ5@976,COG0496@1,COG0496@2	NA|NA|NA	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MAG.T21.45_00050	1122605.KB893644_gene1461	9.5e-86	323.9	Sphingobacteriia	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005		GT19		Bacteria	1IPZM@117747,4NDW3@976,COG0763@1,COG0763@2	NA|NA|NA	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MAG.T21.45_00053	760192.Halhy_0272	1.5e-25	122.9	Sphingobacteriia	hscB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234		ko:K04082,ko:K05801					ko00000,ko03029,ko03110				Bacteria	1J0WA@117747,4PP0Z@976,COG1076@1,COG1076@2	NA|NA|NA	O	HSCB C-terminal oligomerisation domain
MAG.T21.45_00054	760192.Halhy_0271	1.1e-165	589.7	Sphingobacteriia	rseP			ko:K11749	ko02024,ko04112,map02024,map04112				ko00000,ko00001,ko01000,ko01002				Bacteria	1INRC@117747,4NEAR@976,COG0750@1,COG0750@2	NA|NA|NA	M	zinc metalloprotease
MAG.T21.45_00055	1168034.FH5T_21120	1.2e-49	203.4	Bacteroidia	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761					ko00000,ko01000,ko03009				Bacteria	2FKZG@200643,4NE2S@976,COG1385@1,COG1385@2	NA|NA|NA	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MAG.T21.45_00056	760192.Halhy_0269	2.2e-95	355.1	Sphingobacteriia													Bacteria	1IQFD@117747,4NFMT@976,COG1657@1,COG1657@2	NA|NA|NA	I	Domain of unknown function (DUF4159)
MAG.T21.45_00057	1122176.KB903531_gene3004	3.5e-18	97.1	Sphingobacteriia	pspC	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0016020,GO:0019222,GO:0044464,GO:0048518,GO:0050789,GO:0060255,GO:0065007,GO:0071944		ko:K03973					ko00000,ko02048,ko03000				Bacteria	1IUHT@117747,4NUNU@976,COG1983@1,COG1983@2	NA|NA|NA	KT	PFAM PspC domain
MAG.T21.45_00058	1121904.ARBP01000001_gene5865	1.1e-25	123.2	Cytophagia													Bacteria	47RZ6@768503,4NNXM@976,COG2050@1,COG2050@2	NA|NA|NA	Q	Domain of unknown function (DUF4442)
MAG.T21.45_00059	760192.Halhy_5799	6.1e-179	633.6	Sphingobacteriia	sucC		6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQ0Q@117747,4NFHA@976,COG0045@1,COG0045@2	NA|NA|NA	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MAG.T21.45_00060	760192.Halhy_1198	1.1e-105	390.2	Sphingobacteriia	rlmL	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.173,2.1.1.264	ko:K07444,ko:K12297			R07234	RC00003	ko00000,ko01000,ko03009				Bacteria	1IQEJ@117747,4NFJM@976,COG0116@1,COG0116@2	NA|NA|NA	L	Belongs to the methyltransferase superfamily
MAG.T21.45_00062	1123277.KB893194_gene5876	1e-97	363.6	Cytophagia		GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009712,GO:0009987,GO:0016853,GO:0016854,GO:0016872,GO:0018850,GO:0018958,GO:0019336,GO:0019439,GO:0019614,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044248,GO:0046872,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901575,GO:1901615,GO:1901616	5.1.1.20	ko:K19802			R10938	RC03309	ko00000,ko01000				Bacteria	47N8Q@768503,4NEBX@976,COG4948@1,COG4948@2	NA|NA|NA	M	mandelate racemase muconate lactonizing
MAG.T21.45_00063	983548.Krodi_1743	4e-42	177.9	Dokdonia	trmH		2.1.1.185,2.1.1.34	ko:K00556,ko:K03218,ko:K03437					ko00000,ko01000,ko03009,ko03016				Bacteria	1HY0Q@117743,37DTX@326319,4NM8C@976,COG0566@1,COG0566@2	NA|NA|NA	J	SpoU rRNA Methylase family
MAG.T21.45_00064	754476.Q7A_2804	5.4e-15	87.4	Gammaproteobacteria			4.3.1.27	ko:K20757					ko00000,ko01000				Bacteria	1N80E@1224,1SZSF@1236,COG2105@1,COG2105@2	NA|NA|NA	S	Gamma-glutamyl cyclotransferase, AIG2-like
MAG.T21.45_00065	1122176.KB903554_gene3859	3.9e-109	401.7	Sphingobacteriia			4.4.1.11,4.4.1.8	ko:K01760,ko:K01761	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00654,R00782,R01286,R02408,R04770,R04941	RC00056,RC00069,RC00196,RC00348,RC00382,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000				Bacteria	1IP3G@117747,4NJRK@976,COG0626@1,COG0626@2	NA|NA|NA	E	Cys/Met metabolism PLP-dependent enzyme
MAG.T21.45_00066	760192.Halhy_5774	0.0	1191.4	Bacteroidetes													Bacteria	28I1Q@1,2Z869@2,4NH2E@976	NA|NA|NA		
MAG.T21.45_00067	760192.Halhy_5773	1.3e-71	276.6	Sphingobacteriia	prmA			ko:K02687					ko00000,ko01000,ko03009				Bacteria	1IQ5D@117747,4NFRW@976,COG2264@1,COG2264@2	NA|NA|NA	J	Ribosomal protein L11 methyltransferase
MAG.T21.45_00068	760192.Halhy_5771	4.2e-105	387.9	Sphingobacteriia	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQDT@117747,4NEJP@976,COG0190@1,COG0190@2	NA|NA|NA	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MAG.T21.45_00069	760192.Halhy_5769	9e-195	688.0	Bacteroidetes			3.2.1.4,5.2.1.8	ko:K01179,ko:K03768,ko:K08738	ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko03110	3.D.4.6	GH5,GH9		Bacteria	4NDZC@976,COG3291@1,COG3291@2,COG4935@1,COG4935@2	NA|NA|NA	DZ	Pkd domain containing protein
MAG.T21.45_00070	760192.Halhy_0303	2.6e-48	199.5	Sphingobacteriia				ko:K06076					ko00000,ko02000	1.B.9			Bacteria	1IQ3Y@117747,4NIU4@976,COG2067@1,COG2067@2	NA|NA|NA	I	protein CHP03519, membrane, Bacteroidetes
MAG.T21.45_00072	760192.Halhy_0085	9.9e-39	166.8	Sphingobacteriia				ko:K03088					ko00000,ko03021				Bacteria	1ISH7@117747,4NQCH@976,COG1595@1,COG1595@2	NA|NA|NA	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MAG.T21.45_00073	1122179.KB890423_gene2291	4.2e-135	488.0	Sphingobacteriia	lysA		4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000				Bacteria	1INXN@117747,4NE7X@976,COG0019@1,COG0019@2	NA|NA|NA	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MAG.T21.45_00074	760192.Halhy_0087	0.0	1309.3	Sphingobacteriia	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iLJ478.TM1817	Bacteria	1IPEY@117747,4NETB@976,COG0525@1,COG0525@2	NA|NA|NA	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MAG.T21.45_00075	1122176.KB903598_gene4646	3.4e-29	136.7	Bacteria													Bacteria	COG4935@1,COG4935@2	NA|NA|NA	O	Belongs to the peptidase S8 family
MAG.T21.45_00076	755732.Fluta_2363	1.6e-60	240.0	Cryomorphaceae	rfaE		2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1ICPR@117743,2PBJC@246874,4NHUV@976,COG2870@1,COG2870@2	NA|NA|NA	M	pfkB family carbohydrate kinase
MAG.T21.45_00077	927658.AJUM01000034_gene365	2.2e-67	263.1	Marinilabiliaceae	waaA	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527,ko:K03439	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03016		GT30		Bacteria	2FPNI@200643,3XJDE@558415,4NESA@976,COG1519@1,COG1519@2	NA|NA|NA	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)
MAG.T21.45_00078	760192.Halhy_6283	1.4e-30	140.2	Bacteroidetes													Bacteria	2EA9Q@1,334E4@2,4NX5I@976	NA|NA|NA		
MAG.T21.45_00079	760192.Halhy_6284	1.6e-150	538.9	Sphingobacteriia	rfbB		4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPW2@117747,4NEZX@976,COG0451@1,COG0451@2	NA|NA|NA	GM	NAD dependent epimerase dehydratase family
MAG.T21.45_00080	1349785.BAUG01000006_gene571	1.2e-138	499.6	Flavobacteriia	rfbB		4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000				Bacteria	1HX7N@117743,4NE9V@976,COG1088@1,COG1088@2	NA|NA|NA	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MAG.T21.45_00081	760192.Halhy_6399	4.9e-90	337.8	Sphingobacteriia	mvaB		4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQRT@117747,4NDZH@976,COG0119@1,COG0119@2	NA|NA|NA	E	Hydroxymethylglutaryl-CoA lyase
MAG.T21.45_00082	760192.Halhy_6341	2.6e-82	312.4	Sphingobacteriia				ko:K00666					ko00000,ko01000,ko01004				Bacteria	1IPM0@117747,4NDXK@976,COG0318@1,COG0318@2	NA|NA|NA	IQ	Acyl-protein synthetase, LuxE
MAG.T21.45_00084	760192.Halhy_0288	7e-108	397.1	Sphingobacteriia	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQE1@117747,4NFZS@976,COG0408@1,COG0408@2	NA|NA|NA	H	coproporphyrinogen III oxidase
MAG.T21.45_00085	714943.Mucpa_3897	3.7e-72	278.5	Sphingobacteriia	udp		2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100		R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000				Bacteria	1INVP@117747,4NG5S@976,COG2820@1,COG2820@2	NA|NA|NA	F	phosphorylase
MAG.T21.45_00086	760192.Halhy_0121	8.2e-31	139.8	Sphingobacteriia	gldC												Bacteria	1ISTG@117747,2AGY9@1,3176X@2,4NQD4@976	NA|NA|NA	S	TIGRFAM Gliding motility-associated protein, GldC
MAG.T21.45_00087	1122176.KB903538_gene1475	1.6e-70	273.1	Sphingobacteriia													Bacteria	1IUAK@117747,2BG4X@1,33858@2,4NW0E@976	NA|NA|NA	S	Domain of unknown function (DUF4249)
MAG.T21.45_00088	760192.Halhy_0181	9.3e-191	673.7	Sphingobacteriia	copA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016		R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5			Bacteria	1IPEH@117747,4NERS@976,COG2217@1,COG2217@2	NA|NA|NA	P	ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter
MAG.T21.45_00089	391603.FBALC1_10657	1.9e-171	609.0	Flavobacteriia			6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000				Bacteria	1HXNP@117743,4NM1W@976,COG4770@1,COG4770@2	NA|NA|NA	I	Biotin carboxylase
MAG.T21.45_00091	984262.SGRA_1443	2e-42	179.5	Sphingobacteriia													Bacteria	1IQ7T@117747,4NDUW@976,COG2932@1,COG2932@2	NA|NA|NA	K	transcriptional regulator
MAG.T21.45_00092	760192.Halhy_5239	3.2e-72	278.5	Sphingobacteriia	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147			iJN746.PP_4715	Bacteria	1IPGF@117747,4NE2F@976,COG0149@1,COG0149@2	NA|NA|NA	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MAG.T21.45_00093	760192.Halhy_5226	1.6e-70	273.1	Sphingobacteriia													Bacteria	1IP8N@117747,4NHAD@976,COG1801@1,COG1801@2	NA|NA|NA	S	Protein of unknown function DUF72
MAG.T21.45_00094	760192.Halhy_5961	1.3e-277	962.2	Sphingobacteriia	ppk		2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018				ko00000,ko00001,ko01000,ko03019				Bacteria	1IPGC@117747,4NE3P@976,COG0855@1,COG0855@2	NA|NA|NA	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MAG.T21.45_00097	1550091.JROE01000006_gene2472	5.4e-142	510.8	Sphingobacteriia													Bacteria	1IRZ6@117747,4NEVS@976,COG1680@1,COG1680@2	NA|NA|NA	V	COG1680 Beta-lactamase class C and other penicillin binding
MAG.T21.45_00098	755732.Fluta_3664	4.5e-46	191.0	Flavobacteriia													Bacteria	1I1YQ@117743,4NPKZ@976,COG2050@1,COG2050@2	NA|NA|NA	Q	Domain of unknown function (DUF4442)
MAG.T21.45_00099	760192.Halhy_2409	1.8e-27	129.4	Sphingobacteriia													Bacteria	1IZ7V@117747,4NMI9@976,COG0664@1,COG0664@2	NA|NA|NA	T	SPTR Protein containing cyclic nucleotide-binding domain
MAG.T21.45_00101	555500.I215_15648	1.3e-139	502.3	Flavobacteriia				ko:K18236					ko00000,ko01504				Bacteria	1I02E@117743,4NIND@976,COG1708@1,COG1708@2	NA|NA|NA	S	Streptomycin adenylyltransferase
MAG.T21.45_00104	1168289.AJKI01000022_gene1879	1.1e-54	221.5	Bacteroidetes													Bacteria	2E69U@1,330XR@2,4NV70@976	NA|NA|NA		
MAG.T21.45_00106	620914.JH621290_gene1531	7.2e-15	87.8	Bacteroidetes													Bacteria	2C6KZ@1,333W9@2,4NWM8@976	NA|NA|NA		
MAG.T21.45_00112	1185876.BN8_01351	1.5e-11	77.4	Cytophagia													Bacteria	2FIX2@1,34AN3@2,47VNK@768503,4P5GJ@976	NA|NA|NA		
MAG.T21.45_00113	1235803.C825_02981	1.6e-30	139.4	Bacteria				ko:K02395					ko00000,ko02035				Bacteria	COG1705@1,COG1705@2	NA|NA|NA	NU	amidase activity
MAG.T21.45_00116	376686.Fjoh_2054	2.6e-11	76.3	Bacteria													Bacteria	COG1372@1,COG1372@2	NA|NA|NA	L	intein-mediated protein splicing
MAG.T21.45_00118	1203611.KB894547_gene2603	1.5e-12	79.7	Rikenellaceae													Bacteria	22VGY@171550,2F4VJ@1,2FTIR@200643,33XHR@2,4P3CJ@976	NA|NA|NA		
MAG.T21.45_00120	1124780.ANNU01000010_gene3712	1.8e-83	315.8	Cytophagia													Bacteria	47TBX@768503,4PDYW@976,COG0827@1,COG0827@2	NA|NA|NA	L	Pfam:Methyltransf_26
MAG.T21.45_00121	1237149.C900_02309	3.5e-31	142.1	Cytophagia	radC			ko:K03630					ko00000				Bacteria	47VQ0@768503,4NRCM@976,COG2003@1,COG2003@2	NA|NA|NA	L	RadC-like JAB domain
MAG.T21.45_00122	1237149.C900_02307	7.3e-14	84.3	Cytophagia	XK27_00500		2.1.1.37,3.1.21.4	ko:K00558,ko:K01155	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036				Bacteria	47MY5@768503,4NEQG@976,COG0270@1,COG0270@2,COG0553@1,COG0553@2	NA|NA|NA	L	Helicase conserved C-terminal domain
MAG.T21.45_00123	269798.CHU_1466	0.0	1195.3	Cytophagia	XK27_00500												Bacteria	47MY5@768503,4NEQG@976,COG0553@1,COG0553@2	NA|NA|NA	L	Helicase conserved C-terminal domain
MAG.T21.45_00124	269798.CHU_1465	2.1e-80	306.6	Cytophagia				ko:K06919					ko00000				Bacteria	47THX@768503,4P216@976,COG1066@1,COG1066@2	NA|NA|NA	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MAG.T21.45_00125	1121011.AUCB01000006_gene1046	3.4e-17	95.1	Arenibacter													Bacteria	1IAN2@117743,23IGN@178469,29T3J@1,34BAC@2,4P69D@976	NA|NA|NA		
MAG.T21.45_00126	391598.FBBAL38_00070	6.3e-55	221.1	Flavobacteriia													Bacteria	1IAE5@117743,4NN6R@976,COG2378@1,COG2378@2	NA|NA|NA	K	WYL domain
MAG.T21.45_00127	167542.P9515_00381	4.4e-48	198.0	Cyanobacteria			3.1.1.32,3.1.1.4	ko:K01058,ko:K07502	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110		R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000				Bacteria	1GA1W@1117,COG0790@1,COG0790@2	NA|NA|NA	S	PFAM T5orf172 domain
MAG.T21.45_00128	761193.Runsl_0097	1.5e-238	832.0	Cytophagia				ko:K06915					ko00000				Bacteria	47X1H@768503,4PBGZ@976,COG0433@1,COG0433@2	NA|NA|NA	S	AAA-like domain
MAG.T21.45_00129	761193.Runsl_0098	1.2e-277	962.2	Cytophagia	dndD			ko:K02057,ko:K03546,ko:K19171		M00221			ko00000,ko00002,ko02000,ko02048,ko03400	3.A.1.2			Bacteria	47Y2G@768503,4PMDY@976,COG0419@1,COG0419@2	NA|NA|NA	L	AAA domain
MAG.T21.45_00130	761193.Runsl_0099	3.1e-17	94.0	Bacteroidetes													Bacteria	2EQU8@1,33IDY@2,4NYGJ@976	NA|NA|NA		
MAG.T21.45_00131	435591.BDI_2135	4.5e-146	525.4	Bacteroidia			3.1.21.5	ko:K01156					ko00000,ko01000,ko02048				Bacteria	2FVII@200643,4NJ7R@976,COG1061@1,COG1061@2	NA|NA|NA	KL	Type III restriction enzyme, res subunit
MAG.T21.45_00132	435591.BDI_2134	2.2e-19	102.1	Porphyromonadaceae			2.1.1.72	ko:K07316					ko00000,ko01000,ko02048				Bacteria	22Y1B@171551,2FNVJ@200643,4NFKE@976,COG2189@1,COG2189@2	NA|NA|NA	L	DNA methylase
MAG.T21.45_00133	1218103.CIN01S_15_00870	1.1e-153	550.1	Chryseobacterium													Bacteria	1HYXS@117743,3ZQ6I@59732,4NEY6@976,COG4584@1,COG4584@2	NA|NA|NA	L	Integrase core domain
MAG.T21.45_00134	1048983.EL17_05870	1.2e-68	266.5	Cytophagia				ko:K02315					ko00000,ko03032				Bacteria	47P7E@768503,4NFE0@976,COG1484@1,COG1484@2	NA|NA|NA	L	PFAM IstB domain protein ATP-binding protein
MAG.T21.45_00137	1034807.FBFL15_1746	2.6e-139	502.3	Bacteroidetes			2.7.8.12	ko:K09809,ko:K21010	ko02025,map02025				ko00000,ko00001,ko01000				Bacteria	4PPEM@976,COG4783@1,COG4783@2	NA|NA|NA	S	chaperone-mediated protein folding
MAG.T21.45_00138	1123400.KB904797_gene1376	7.3e-98	365.2	Thiotrichales				ko:K06993					ko00000				Bacteria	1R41A@1224,1RZ63@1236,461KQ@72273,COG0507@1,COG0507@2	NA|NA|NA	L	UvrD-like helicase C-terminal domain
MAG.T21.45_00140	1131812.JQMS01000001_gene1160	5.3e-35	153.7	Bacteria													Bacteria	2DMPT@1,32SXV@2	NA|NA|NA	S	Domain of unknown function (DUF3127)
MAG.T21.45_00141	1218108.KB908302_gene2793	6.6e-79	301.2	Flavobacteriia	ppsA			ko:K07699,ko:K08088	ko02020,ko02024,map02020,map02024	M00485			ko00000,ko00001,ko00002,ko02022				Bacteria	1I4YR@117743,4NSI1@976,COG2197@1,COG2197@2	NA|NA|NA	T	cheY-homologous receiver domain
MAG.T21.45_00142	1250006.JHZZ01000001_gene2345	9.6e-84	317.4	Flavobacteriia				ko:K03413,ko:K07688	ko02020,ko02030,map02020,map02030	M00506			ko00000,ko00001,ko00002,ko02022,ko02035				Bacteria	1IICF@117743,4NUI1@976,COG2197@1,COG2197@2	NA|NA|NA	T	cheY-homologous receiver domain
MAG.T21.45_00143	1250006.JHZZ01000001_gene2344	3.4e-63	249.2	Flavobacteriia													Bacteria	1I8Y0@117743,2F2MR@1,33VIB@2,4P2BB@976	NA|NA|NA		
MAG.T21.45_00144	1250006.JHZZ01000001_gene2343	3.3e-153	548.5	Flavobacteriia			2.7.7.49	ko:K00986					ko00000,ko01000				Bacteria	1I0E3@117743,4NGJQ@976,COG3344@1,COG3344@2	NA|NA|NA	L	RNA-directed DNA polymerase
MAG.T21.45_00145	1288963.ADIS_1918	3.7e-129	468.0	Cytophagia													Bacteria	47XPV@768503,4NGHM@976,COG2378@1,COG2378@2	NA|NA|NA	K	WYL domain
MAG.T21.45_00148	1121896.JMLU01000015_gene1971	7.5e-89	333.6	Flavobacterium				ko:K09968					ko00000				Bacteria	1I0YU@117743,2NZ9N@237,4NJA4@976,COG3680@1,COG3680@2	NA|NA|NA	O	regulation of methylation-dependent chromatin silencing
MAG.T21.45_00150	32057.KB217472_gene7857	7.3e-209	734.9	Bacteria													Bacteria	COG4249@1,COG4249@2	NA|NA|NA	S	B-1 B cell differentiation
MAG.T21.45_00151	865937.Gilli_2298	2.2e-177	629.4	Gillisia				ko:K09124					ko00000				Bacteria	1ICT2@117743,2P7AQ@244698,4PAFN@976,COG1700@1,COG1700@2	NA|NA|NA	S	Domain of unknown function (DUF2357)
MAG.T21.45_00152	1123037.AUDE01000013_gene552	1e-119	437.6	Bacteroidetes				ko:K07452					ko00000,ko01000,ko02048				Bacteria	4NKDZ@976,COG1401@1,COG1401@2	NA|NA|NA	V	to Escherichia coli 5-methylcytosine-specific restriction enzyme B McrB or RglB or B4346 SWALL MCRB_ECOLI (SWALL P15005) (459 aa) fasta scores E() 7.3e-21, 29.42 id in 333 aa, and to Bacillus cereus 5-methylcytosine-specific restriction related enzyme McrB SWALL Q9XBI7 (EMBL AJ007510) (343 aa) fasta scores E() 6e-14, 32.38 id in 281 aa
MAG.T21.45_00153	1111730.ATTM01000002_gene1130	8.5e-104	383.3	Bacteroidetes													Bacteria	4NRFG@976,COG0270@1,COG0270@2	NA|NA|NA	L	DNA (cytosine-5-)-methyltransferase activity
MAG.T21.45_00154	1410628.JNKS01000023_gene1764	2.7e-137	495.4	unclassified Lachnospiraceae	dcm		2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036				Bacteria	1TSNX@1239,2490C@186801,27J6P@186928,COG0270@1,COG0270@2	NA|NA|NA	L	C-5 cytosine-specific DNA methylase
MAG.T21.45_00155	485918.Cpin_2561	3.2e-48	198.0	Sphingobacteriia	vsr			ko:K07458					ko00000,ko01000,ko03400				Bacteria	1ISW8@117747,4NQEH@976,COG3727@1,COG3727@2	NA|NA|NA	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MAG.T21.45_00156	1033734.CAET01000060_gene2035	1.7e-88	334.3	Bacillus													Bacteria	1UFWR@1239,1ZS0V@1386,4IUG9@91061,COG1100@1,COG1100@2	NA|NA|NA	S	Z1 domain
MAG.T21.45_00157	203275.BFO_0626	8.2e-14	84.7	Porphyromonadaceae													Bacteria	22Z4J@171551,2FPYV@200643,2Z9WJ@2,4NM2Z@976,arCOG12551@1	NA|NA|NA	S	Putative  PD-(D/E)XK family member, (DUF4420)
MAG.T21.45_00159	1492738.FEM21_05180	1.8e-23	114.8	Flavobacterium													Bacteria	1I3Z7@117743,2DMNP@1,2NXMN@237,32SQ4@2,4NT2A@976	NA|NA|NA		
MAG.T21.45_00160	1121899.Q764_13590	1.2e-49	202.6	Flavobacterium				ko:K07065					ko00000				Bacteria	1IKQG@117743,2P0TT@237,4NNQV@976,COG2402@1,COG2402@2	NA|NA|NA	S	PIN domain
MAG.T21.45_00161	761193.Runsl_5080	1.4e-111	409.5	Cytophagia	yhgE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K07471,ko:K13652,ko:K19056					ko00000,ko03000				Bacteria	47RST@768503,4NHWS@976,COG2207@1,COG2207@2,COG3449@1,COG3449@2	NA|NA|NA	K	Bacterial transcription activator, effector binding domain
MAG.T21.45_00162	761193.Runsl_5081	1.2e-45	189.5	Bacteria													Bacteria	COG3832@1,COG3832@2	NA|NA|NA	J	glyoxalase III activity
MAG.T21.45_00163	1239962.C943_02440	3.1e-34	151.4	Bacteroidetes			3.1.21.7	ko:K05982,ko:K07452					ko00000,ko01000,ko02048,ko03400				Bacteria	4NZHS@976,COG3695@1,COG3695@2	NA|NA|NA	L	enzyme binding
MAG.T21.45_00164	1034807.FBFL15_1011	7.3e-56	223.8	Flavobacterium				ko:K06919					ko00000				Bacteria	1I366@117743,2NWRN@237,4NM4B@976,COG5340@1,COG5340@2	NA|NA|NA	K	Psort location Cytoplasmic, score
MAG.T21.45_00165	929562.Emtol_3188	2.5e-19	101.3	Cytophagia				ko:K09144					ko00000				Bacteria	47XQK@768503,4NMIN@976,COG2253@1,COG2253@2	NA|NA|NA	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system
MAG.T21.45_00166	929562.Emtol_3188	4.9e-47	194.1	Cytophagia				ko:K09144					ko00000				Bacteria	47XQK@768503,4NMIN@976,COG2253@1,COG2253@2	NA|NA|NA	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system
MAG.T21.45_00168	1034807.FBFL15_0377	6.7e-119	433.7	Flavobacteriia													Bacteria	1IBPT@117743,4NGSI@976,COG5464@1,COG5464@2	NA|NA|NA	S	to proteins from other organisms
MAG.T21.45_00170	1120965.AUBV01000005_gene1662	4.3e-145	521.2	Cytophagia			3.4.16.4	ko:K01286					ko00000,ko01000				Bacteria	47XBS@768503,4NNBR@976,COG1680@1,COG1680@2	NA|NA|NA	V	Beta-lactamase
MAG.T21.45_00171	929703.KE386491_gene1353	2.1e-34	151.8	Cytophagia			1.14.13.9	ko:K00486	ko00380,ko01100,map00380,map01100	M00038	R01960	RC00046	ko00000,ko00001,ko00002,ko01000				Bacteria	47QNN@768503,4NMI5@976,COG0702@1,COG0702@2	NA|NA|NA	GM	NAD(P)H-binding
MAG.T21.45_00172	1048983.EL17_21420	7.7e-138	496.9	Cytophagia													Bacteria	47M65@768503,4NGY8@976,COG4804@1,COG4804@2	NA|NA|NA	S	Protein of unknown function (DUF1016)
MAG.T21.45_00174	760192.Halhy_6342	5.5e-280	969.9	Sphingobacteriia	typA	GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840		ko:K06207					ko00000				Bacteria	1IQXV@117747,4NDVM@976,COG1217@1,COG1217@2	NA|NA|NA	T	GTP-binding protein TypA
MAG.T21.45_00175	760192.Halhy_6202	0.0	1201.0	Sphingobacteriia													Bacteria	1IV0S@117747,4NESU@976,COG4447@1,COG4447@2	NA|NA|NA	S	Sortilin, neurotensin receptor 3,
MAG.T21.45_00176	760192.Halhy_0950	4.3e-132	478.4	Sphingobacteriia				ko:K07091,ko:K11720	ko02010,map02010	M00320			ko00000,ko00001,ko00002,ko02000	1.B.42.1			Bacteria	1INY8@117747,4NE8B@976,COG0795@1,COG0795@2	NA|NA|NA	S	Permease, YjgP YjgQ family
MAG.T21.45_00177	760192.Halhy_0949	2.1e-21	109.4	Sphingobacteriia			3.6.1.27	ko:K19302	ko00550,map00550		R05627	RC00002	ko00000,ko00001,ko01000,ko01011				Bacteria	1ITA7@117747,4NV5Q@976,COG0671@1,COG0671@2	NA|NA|NA	I	PFAM Phosphatidic acid phosphatase type 2 haloperoxidase
MAG.T21.45_00178	649349.Lbys_3143	5.2e-97	361.7	Cytophagia	rsmF	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176,2.1.1.178	ko:K03500,ko:K11392					ko00000,ko01000,ko03009				Bacteria	47KID@768503,4NEV7@976,COG0144@1,COG0144@2,COG3270@1,COG3270@2	NA|NA|NA	J	RNA-binding PUA-like domain of methyltransferase RsmF
MAG.T21.45_00179	1122176.KB903531_gene3063	2.8e-53	216.5	Sphingobacteriia													Bacteria	1IP8T@117747,4NEVQ@976,COG2244@1,COG2244@2	NA|NA|NA	S	Membrane protein involved in the export of O-antigen and teichoic acid
MAG.T21.45_00180	760192.Halhy_0933	1e-113	416.8	Sphingobacteriia	gpsA	GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.1.1.94	ko:K00057,ko:K07175	ko00564,ko01110,map00564,map01110		R00842,R00844	RC00029	ko00000,ko00001,ko01000			iJN678.gpsA,iJN746.PP_4169	Bacteria	1IQF4@117747,4NF4R@976,COG0240@1,COG0240@2	NA|NA|NA	I	Glycerol-3-phosphate dehydrogenase
MAG.T21.45_00181	760192.Halhy_0931	2.5e-71	275.4	Sphingobacteriia	truB	GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481	5.4.99.25	ko:K03177					ko00000,ko01000,ko03016				Bacteria	1IPMS@117747,4NESK@976,COG0130@1,COG0130@2	NA|NA|NA	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MAG.T21.45_00182	1296415.JACC01000041_gene37	5.8e-77	294.3	Aquimarina	uppP		3.6.1.27	ko:K06153	ko00550,map00550		R05627	RC00002	ko00000,ko00001,ko01000,ko01011				Bacteria	1HWSY@117743,2YI5S@290174,4NGIZ@976,COG1968@1,COG1968@2	NA|NA|NA	V	Bacitracin resistance protein BacA
MAG.T21.45_00183	700598.Niako_6937	8.9e-11	73.2	Sphingobacteriia	fjo13												Bacteria	1IUJM@117747,2E6VD@1,331EZ@2,4NUSW@976	NA|NA|NA	S	Protein of unknown function (DUF3098)
MAG.T21.45_00184	760192.Halhy_0928	4.6e-67	261.5	Sphingobacteriia	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976		ko:K09811,ko:K09812	ko02010,map02010	M00256			ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140			Bacteria	1INNN@117747,4NH05@976,COG2177@1,COG2177@2	NA|NA|NA	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily
MAG.T21.45_00185	760192.Halhy_0927	2.6e-18	98.6	Bacteria													Bacteria	298XI@1,2ZW1D@2	NA|NA|NA		
MAG.T21.45_00186	760192.Halhy_0743	0.0	1371.3	Sphingobacteriia	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	1IP89@117747,4NE5K@976,COG0495@1,COG0495@2	NA|NA|NA	J	Belongs to the class-I aminoacyl-tRNA synthetase family
MAG.T21.45_00187	760192.Halhy_6210	2.4e-180	639.0	Sphingobacteriia	pal			ko:K03640					ko00000,ko02000	2.C.1.2			Bacteria	1IPAI@117747,4NE6G@976,COG0457@1,COG0457@2,COG2885@1,COG2885@2	NA|NA|NA	M	Belongs to the ompA family
MAG.T21.45_00188	760192.Halhy_6212	1.6e-308	1065.4	Sphingobacteriia	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944		ko:K03072,ko:K03074,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7			Bacteria	1IP7W@117747,4NE1X@976,COG0341@1,COG0341@2,COG0342@1,COG0342@2	NA|NA|NA	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MAG.T21.45_00189	760192.Halhy_6218	5.3e-88	331.3	Sphingobacteriia			1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPKW@117747,4NIHV@976,COG1052@1,COG1052@2	NA|NA|NA	CH	D-isomer specific 2-hydroxyacid dehydrogenase
MAG.T21.45_00191	760192.Halhy_6221	4.3e-125	455.3	Sphingobacteriia	ktrB			ko:K03498					ko00000,ko02000	2.A.38.1,2.A.38.4			Bacteria	1IREE@117747,4NF7R@976,COG0168@1,COG0168@2	NA|NA|NA	P	Cation transport protein
MAG.T21.45_00192	760192.Halhy_1427	4.7e-46	191.4	Sphingobacteriia	ktrA			ko:K03499					ko00000,ko02000	2.A.38.1,2.A.38.4			Bacteria	1IPNR@117747,4NGRQ@976,COG0569@1,COG0569@2	NA|NA|NA	P	TrkA-N domain
MAG.T21.45_00193	1122176.KB903576_gene5021	7.7e-53	213.4	Sphingobacteriia	XK27_03185			ko:K16785	ko02010,map02010	M00582			ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	1ISBK@117747,4NNW2@976,COG4696@1,COG4696@2	NA|NA|NA	S	Phosphoribosyl-ATP pyrophosphohydrolase
MAG.T21.45_00194	760192.Halhy_1164	4.5e-147	528.1	Bacteroidetes													Bacteria	4NEHY@976,COG2234@1,COG2234@2	NA|NA|NA	S	Peptidase m28
MAG.T21.45_00195	760192.Halhy_1163	3.8e-66	258.5	Bacteria													Bacteria	COG0697@1,COG0697@2	NA|NA|NA	EG	spore germination
MAG.T21.45_00196	1122176.KB903531_gene3018	3.9e-114	417.9	Sphingobacteriia	ilvE_1		2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1IPAA@117747,4NI83@976,COG0115@1,COG0115@2	NA|NA|NA	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MAG.T21.45_00197	641524.ADICYQ_4098	5.9e-60	237.7	Cytophagia													Bacteria	2C3PP@1,2Z954@2,47V30@768503,4NIZX@976	NA|NA|NA		
MAG.T21.45_00199	867900.Celly_0702	3.4e-33	149.4	Cellulophaga	ygjK	GO:0003674,GO:0003824,GO:0004553,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015926,GO:0016787,GO:0016798,GO:0033554,GO:0050896,GO:0051716		ko:K03931					ko00000		GH63		Bacteria	1F856@104264,1IJB6@117743,4PKJT@976,COG1626@1,COG1626@2	NA|NA|NA	G	Trehalase
MAG.T21.45_00200	1122176.KB903576_gene5019	5e-70	271.6	Sphingobacteriia	dhdh												Bacteria	1IXS5@117747,4NE07@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_00201	1123277.KB893221_gene6164	5.4e-99	367.9	Cytophagia	phoD		3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	47KAV@768503,4NDUS@976,COG3540@1,COG3540@2	NA|NA|NA	P	PhoD-like phosphatase
MAG.T21.45_00202	760192.Halhy_1183	0.0	2280.4	Sphingobacteriia	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230		R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000				Bacteria	1IP8F@117747,4NFKH@976,COG0067@1,COG0067@2,COG0069@1,COG0069@2,COG0070@1,COG0070@2	NA|NA|NA	E	glutamate synthase
MAG.T21.45_00203	760192.Halhy_1182	2.4e-198	698.4	Sphingobacteriia	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230		R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000			iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450	Bacteria	1IPJB@117747,4NG9R@976,COG0493@1,COG0493@2	NA|NA|NA	C	TIGRFAM glutamate synthase, NADH NADPH, small subunit
MAG.T21.45_00204	1336803.PHEL49_1903	1.7e-56	225.7	Polaribacter	plsC2												Bacteria	1I28N@117743,3VVH1@52959,4NNG7@976,COG0204@1,COG0204@2	NA|NA|NA	I	Phosphate acyltransferases
MAG.T21.45_00205	760192.Halhy_1205	1.4e-59	236.1	Sphingobacteriia	marC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944		ko:K05595					ko00000,ko02000	2.A.95.1			Bacteria	1IYKC@117747,4NIHF@976,COG2095@1,COG2095@2	NA|NA|NA	U	MarC family integral membrane protein
MAG.T21.45_00206	402612.FP1526	3.6e-35	154.1	Flavobacterium	cas2			ko:K09951					ko00000,ko02048				Bacteria	1I2XP@117743,2NWAQ@237,4NQ8Z@976,COG3512@1,COG3512@2	NA|NA|NA	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MAG.T21.45_00207	1121897.AUGO01000013_gene3164	7.7e-102	377.1	Flavobacterium	cas1			ko:K15342					ko00000,ko02048,ko03400				Bacteria	1HXPS@117743,2NSAJ@237,4NEKQ@976,COG1518@1,COG1518@2	NA|NA|NA	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MAG.T21.45_00208	1121897.AUGO01000013_gene3165	0.0	1357.0	Flavobacterium	cas9			ko:K09952					ko00000,ko01000,ko02048				Bacteria	1HYZN@117743,2NTXY@237,4NFM9@976,COG3513@1,COG3513@2	NA|NA|NA	L	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MAG.T21.45_00209	1122179.KB890413_gene4698	3.9e-153	548.1	Bacteroidetes													Bacteria	2DBBI@1,2Z888@2,4NQB6@976	NA|NA|NA	S	YHYH protein
MAG.T21.45_00210	391598.FBBAL38_11469	1.6e-52	214.2	Flavobacteriia													Bacteria	1I4NQ@117743,4NTMP@976,COG4704@1,COG4704@2,COG5295@1,COG5295@2	NA|NA|NA	UW	Hep Hag repeat protein
MAG.T21.45_00211	755732.Fluta_2820	6.6e-104	384.0	Flavobacteriia			1.11.1.5	ko:K00428					ko00000,ko01000				Bacteria	1HXUF@117743,4NE4P@976,COG1858@1,COG1858@2	NA|NA|NA	C	cytochrome C peroxidase
MAG.T21.45_00212	1122179.KB890413_gene4693	5.3e-39	167.9	Sphingobacteriia													Bacteria	1IZ48@117747,2DNNM@1,32YAS@2,4NVE7@976	NA|NA|NA		
MAG.T21.45_00213	1123248.KB893386_gene1969	6.3e-184	651.0	Sphingobacteriia	ssdA		1.2.99.10	ko:K22445					ko00000,ko01000				Bacteria	1IPQB@117747,4NEB7@976,COG1012@1,COG1012@2	NA|NA|NA	C	Belongs to the aldehyde dehydrogenase family
MAG.T21.45_00214	509635.N824_06000	3.5e-160	571.2	Sphingobacteriia	gbd		1.1.1.1,1.1.1.61	ko:K00001,ko:K00043,ko:K00100,ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220		R00623,R00754,R01644,R02124,R03544,R03545,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000				Bacteria	1ISP5@117747,4NIU1@976,COG1454@1,COG1454@2	NA|NA|NA	C	Iron-containing alcohol dehydrogenase
MAG.T21.45_00215	1123248.KB893386_gene1972	2.3e-187	661.8	Sphingobacteriia	ipuC		6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727		R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147				Bacteria	1IPJ3@117747,4NHET@976,COG0174@1,COG0174@2	NA|NA|NA	E	Glutamine synthetase, catalytic domain
MAG.T21.45_00216	1123248.KB893385_gene4870	2.5e-157	562.0	Sphingobacteriia	eat			ko:K16238					ko00000,ko02000	2.A.3.5			Bacteria	1IQ7E@117747,4PN7J@976,COG0833@1,COG0833@2	NA|NA|NA	E	Amino acid permease
MAG.T21.45_00217	984262.SGRA_1614	2.5e-39	168.7	Sphingobacteriia	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141		ko:K03088					ko00000,ko03021				Bacteria	1IXQF@117747,4NEFR@976,COG1595@1,COG1595@2	NA|NA|NA	K	Sigma-70, region 4
MAG.T21.45_00218	760192.Halhy_2727	9e-78	297.0	Sphingobacteriia	yfiO			ko:K05807,ko:K08309					ko00000,ko01000,ko01011,ko02000	1.B.33.1	GH23		Bacteria	1IPXN@117747,4NJ5A@976,COG4105@1,COG4105@2	NA|NA|NA	S	outer membrane assembly lipoprotein YfiO
MAG.T21.45_00219	760192.Halhy_2726	1.6e-36	158.7	Sphingobacteriia	rpoZ												Bacteria	1ISVJ@117747,2CT4B@1,32SSJ@2,4NQ76@976	NA|NA|NA	K	RNA polymerase
MAG.T21.45_00220	760192.Halhy_2724	9.5e-73	280.4	Sphingobacteriia													Bacteria	1IPUY@117747,28HA8@1,2Z7MQ@2,4NEJD@976	NA|NA|NA	S	Domain of unknown function (DUF4835)
MAG.T21.45_00221	760192.Halhy_2658	7.3e-118	430.6	Sphingobacteriia	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000				Bacteria	1IXGK@117747,4NETC@976,COG0182@1,COG0182@2	NA|NA|NA	J	Initiation factor 2 subunit family
MAG.T21.45_00222	1122176.KB903541_gene225	2.9e-44	185.3	Bacteroidetes			2.2.1.8,4.1.2.17	ko:K01628,ko:K18847	ko00051,ko01120,map00051,map01120		R02262	RC00603,RC00604	ko00000,ko00001,ko01000				Bacteria	4P3KA@976,COG0235@1,COG0235@2	NA|NA|NA	G	Class II Aldolase and Adducin N-terminal domain
MAG.T21.45_00223	1122176.KB903598_gene4589	6.4e-153	549.3	Sphingobacteriia													Bacteria	1IUXA@117747,4NFAX@976,COG1572@1,COG1572@2	NA|NA|NA	S	Peptidase family C25
MAG.T21.45_00224	98439.AJLL01000098_gene1929	3.4e-25	122.5	Bacteria													Bacteria	COG1215@1,COG1215@2	NA|NA|NA	M	transferase activity, transferring glycosyl groups
MAG.T21.45_00225	761193.Runsl_1737	5.6e-33	148.7	Bacteria													Bacteria	COG0438@1,COG0438@2	NA|NA|NA	M	transferase activity, transferring glycosyl groups
MAG.T21.45_00226	1300143.CCAV010000003_gene1730	2.3e-14	86.7	Chryseobacterium													Bacteria	1I0S3@117743,28IBW@1,2Z8EB@2,3ZQ4B@59732,4NJPW@976	NA|NA|NA		
MAG.T21.45_00228	1034807.FBFL15_0377	2.3e-127	461.8	Flavobacteriia													Bacteria	1IBPT@117743,4NGSI@976,COG5464@1,COG5464@2	NA|NA|NA	S	to proteins from other organisms
MAG.T21.45_00229	700598.Niako_6770	2.4e-19	102.8	Sphingobacteriia													Bacteria	1IZ5U@117747,4NWRI@976,COG2242@1,COG2242@2	NA|NA|NA	H	Methyltransferase FkbM domain
MAG.T21.45_00230	491205.JARQ01000003_gene1964	1.9e-56	227.3	Chryseobacterium			6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110		R00578	RC00010	ko00000,ko00001,ko01000,ko01002				Bacteria	1HXV0@117743,3ZRI7@59732,4NFQ3@976,COG0367@1,COG0367@2	NA|NA|NA	E	Glutamine amidotransferase domain
MAG.T21.45_00231	765912.Thimo_0027	6.8e-22	111.7	Bacteria													Bacteria	COG2348@1,COG2348@2	NA|NA|NA	V	transferase activity, transferring amino-acyl groups
MAG.T21.45_00233	1123277.KB893204_gene6279	5.1e-18	99.0	Bacteria													Bacteria	COG4447@1,COG4447@2	NA|NA|NA	S	cellulose binding
MAG.T21.45_00234	1122176.KB903565_gene3266	1.5e-25	122.1	Sphingobacteriia	atpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		iHN637.CLJU_RS01195,iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190	Bacteria	1ITVV@117747,4NUYG@976,COG0355@1,COG0355@2	NA|NA|NA	C	ATP synthase
MAG.T21.45_00235	760192.Halhy_3110	8.2e-250	869.4	Sphingobacteriia	atpD		3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1			Bacteria	1IPG7@117747,4NF1Q@976,COG0055@1,COG0055@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MAG.T21.45_00236	929713.NIASO_09040	2.3e-86	326.2	Sphingobacteriia	gmhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914	2.7.7.13,2.7.7.71,3.1.3.15,3.1.3.82,3.1.3.83,4.2.1.19	ko:K00966,ko:K01089,ko:K03273,ko:K15669	ko00051,ko00340,ko00520,ko00540,ko01100,ko01110,ko01230,map00051,map00340,map00520,map00540,map01100,map01110,map01230	M00026,M00064,M00114,M00361,M00362	R00885,R03013,R03457,R05647,R09771,R09772	RC00002,RC00017,RC00932	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1IPMP@117747,4NFDB@976,COG0241@1,COG0241@2,COG1208@1,COG1208@2	NA|NA|NA	JM	Nucleotidyl transferase
MAG.T21.45_00237	760192.Halhy_2162	1.2e-57	231.5	Sphingobacteriia													Bacteria	1INTG@117747,4NKKC@976,COG4219@1,COG4219@2	NA|NA|NA	KT	PFAM Peptidase M56, BlaR1
MAG.T21.45_00238	1122621.ATZA01000056_gene4066	8.5e-29	133.3	Sphingobacteriia	blal												Bacteria	1ISTV@117747,4NSQR@976,COG3682@1,COG3682@2	NA|NA|NA	K	Transcriptional repressor, CopY family
MAG.T21.45_00239	760192.Halhy_2164	8.5e-19	100.1	Sphingobacteriia													Bacteria	1IUGD@117747,4P9WM@976,COG4704@1,COG4704@2	NA|NA|NA	S	Uncharacterized protein conserved in bacteria (DUF2141)
MAG.T21.45_00240	760192.Halhy_6038	4.7e-244	850.5	Sphingobacteriia	fadE		1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212		R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000				Bacteria	1IPBZ@117747,4NG2G@976,COG1960@1,COG1960@2	NA|NA|NA	I	acyl-CoA dehydrogenase
MAG.T21.45_00241	1122176.KB903560_gene3539	1.6e-25	122.5	Sphingobacteriia													Bacteria	1ITHM@117747,2AMB7@1,31C6A@2,4NQ8I@976	NA|NA|NA		
MAG.T21.45_00242	1313421.JHBV01000003_gene581	2.2e-38	166.8	Sphingobacteriia	CP_1020												Bacteria	1IPWS@117747,4NI9R@976,COG4715@1,COG4715@2	NA|NA|NA	S	Zinc finger SWIM domain protein
MAG.T21.45_00243	760192.Halhy_2561	1.7e-90	339.0	Sphingobacteriia	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205				ko00000,ko00001,ko01000,ko03009,ko03019,ko03036				Bacteria	1IPYG@117747,4NE0N@976,COG0571@1,COG0571@2	NA|NA|NA	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MAG.T21.45_00244	760192.Halhy_2560	6.2e-174	617.1	Sphingobacteriia	fabF		2.3.1.179	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004			iSB619.SA_RS04785	Bacteria	1IPBP@117747,4NEKC@976,COG0304@1,COG0304@2	NA|NA|NA	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MAG.T21.45_00245	1313301.AUGC01000004_gene2367	2.1e-22	111.3	Bacteroidetes	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509		ko:K02078					ko00000,ko00001				Bacteria	4NS6C@976,COG0236@1,COG0236@2	NA|NA|NA	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MAG.T21.45_00246	1122176.KB903548_gene1151	3e-201	708.0	Sphingobacteriia	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147			iAF987.Gmet_0122	Bacteria	1IPRW@117747,4NEEU@976,COG0469@1,COG0469@2	NA|NA|NA	G	Belongs to the pyruvate kinase family
MAG.T21.45_00247	760192.Halhy_3009	6e-28	132.5	Sphingobacteriia													Bacteria	1IR0N@117747,4NDVW@976,COG0457@1,COG0457@2	NA|NA|NA	S	PFAM Tetratricopeptide
MAG.T21.45_00248	760192.Halhy_3010	7.7e-31	141.0	Sphingobacteriia													Bacteria	1ITXE@117747,4NFYQ@976,COG2834@1,COG2834@2	NA|NA|NA	M	Domain of unknown function (DUF4292)
MAG.T21.45_00249	760192.Halhy_3011	2.4e-79	302.8	Sphingobacteriia	envC												Bacteria	1INMH@117747,4NH2T@976,COG4942@1,COG4942@2	NA|NA|NA	D	Peptidase, M23
MAG.T21.45_00250	760192.Halhy_3012	3.5e-158	564.7	Sphingobacteriia	hflX			ko:K03665					ko00000,ko03009				Bacteria	1IR5V@117747,4NF0P@976,COG2262@1,COG2262@2	NA|NA|NA	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MAG.T21.45_00252	760192.Halhy_3533	7.4e-168	597.0	Sphingobacteriia				ko:K07576,ko:K07577					ko00000				Bacteria	1IQ1N@117747,4NESD@976,COG1236@1,COG1236@2	NA|NA|NA	J	exonuclease of the beta-lactamase fold involved in RNA processing
MAG.T21.45_00253	760192.Halhy_3019	1.6e-42	180.3	Bacteroidetes													Bacteria	4NJWY@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.45_00254	1313421.JHBV01000030_gene2109	5.5e-13	82.8	Bacteria				ko:K12287					ko00000,ko02044				Bacteria	COG3420@1,COG3420@2	NA|NA|NA	P	alginic acid biosynthetic process
MAG.T21.45_00255	760192.Halhy_2219	4.6e-27	127.9	Sphingobacteriia	ompH			ko:K06142					ko00000				Bacteria	1ITN8@117747,4NSCM@976,COG2825@1,COG2825@2	NA|NA|NA	M	PFAM outer membrane chaperone Skp (OmpH)
MAG.T21.45_00256	616991.JPOO01000003_gene1613	9.2e-59	233.4	Arenibacter	polX			ko:K02347,ko:K04477					ko00000,ko03400				Bacteria	1I5QH@117743,23GC0@178469,4NMBC@976,COG1387@1,COG1387@2	NA|NA|NA	E	Domain of Unknown Function (DUF1080)
MAG.T21.45_00257	760192.Halhy_4008	9.8e-66	256.9	Sphingobacteriia	CP_0228		3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPT2@117747,4NE36@976,COG1579@1,COG1579@2	NA|NA|NA	S	Zinc ribbon domain
MAG.T21.45_00258	1288963.ADIS_2880	1.4e-70	273.5	Cytophagia	yqfO		3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000				Bacteria	47JGH@768503,4NF51@976,COG0327@1,COG0327@2	NA|NA|NA	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MAG.T21.45_00259	1150600.ADIARSV_1954	2.1e-32	145.6	Sphingobacteriia	hldE		2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1ISYY@117747,4NNKK@976,COG0615@1,COG0615@2	NA|NA|NA	IM	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MAG.T21.45_00260	760192.Halhy_3524	5.7e-46	191.0	Sphingobacteriia				ko:K07027					ko00000,ko02000	4.D.2			Bacteria	1ISJK@117747,4NGPD@976,COG0392@1,COG0392@2	NA|NA|NA	S	Lysylphosphatidylglycerol synthase TM region
MAG.T21.45_00261	938709.AUSH02000020_gene1986	1.2e-76	294.7	Bacteroidetes													Bacteria	4NHDQ@976,COG3656@1,COG3656@2,COG5295@1,COG5295@2	NA|NA|NA	UW	fibronectin type III domain protein
MAG.T21.45_00262	929703.KE386491_gene1582	1.6e-167	595.9	Cytophagia				ko:K03294					ko00000	2.A.3.2			Bacteria	47MX2@768503,4NJPZ@976,COG0531@1,COG0531@2	NA|NA|NA	E	Amino acid permease
MAG.T21.45_00263	929703.KE386491_gene1583	3.9e-137	494.6	Cytophagia		GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009712,GO:0009987,GO:0016853,GO:0016854,GO:0016872,GO:0018850,GO:0018958,GO:0019336,GO:0019439,GO:0019614,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044248,GO:0046872,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901575,GO:1901615,GO:1901616	5.1.1.20	ko:K19802			R10938	RC03309	ko00000,ko01000				Bacteria	47N8Q@768503,4NEBX@976,COG4948@1,COG4948@2	NA|NA|NA	M	mandelate racemase muconate lactonizing
MAG.T21.45_00264	929562.Emtol_4269	4.1e-147	527.7	Cytophagia													Bacteria	47NP1@768503,4NGXN@976,COG3367@1,COG3367@2	NA|NA|NA	S	Domain of unknown function (DUF1611_N) Rossmann-like domain
MAG.T21.45_00265	1123242.JH636436_gene233	2.6e-93	349.4	Planctomycetes													Bacteria	28IU8@1,2IXJA@203682,2Z8T0@2	NA|NA|NA		
MAG.T21.45_00266	555079.Toce_1567	5.3e-65	255.0	Thermoanaerobacterales			1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130		R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000				Bacteria	1TR4Z@1239,25CDT@186801,42J4N@68295,COG0334@1,COG0334@2	NA|NA|NA	C	Belongs to the Glu Leu Phe Val dehydrogenases family
MAG.T21.45_00267	1123277.KB893176_gene3732	2.7e-152	545.4	Cytophagia			3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000				Bacteria	47KC3@768503,4NHDD@976,COG3653@1,COG3653@2	NA|NA|NA	Q	PFAM D-aminoacylase, C-terminal region
MAG.T21.45_00268	118161.KB235922_gene2360	3.2e-144	518.8	Cyanobacteria													Bacteria	1G5M7@1117,COG1680@1,COG1680@2	NA|NA|NA	V	Beta-lactamase class C
MAG.T21.45_00269	906888.JCM19314_1585	5.4e-123	448.0	Nonlabens													Bacteria	1HXIK@117743,3HJBA@363408,4NEK3@976,COG0277@1,COG0277@2	NA|NA|NA	C	FAD linked oxidases, C-terminal domain
MAG.T21.45_00271	1296416.JACB01000003_gene841	7.8e-78	297.4	Aquimarina	alsR												Bacteria	1HZVD@117743,2YJ78@290174,4NGAB@976,COG0583@1,COG0583@2	NA|NA|NA	K	LysR substrate binding domain
MAG.T21.45_00274	1296416.JACB01000001_gene3167	5.8e-10	70.9	Aquimarina													Bacteria	1HY6X@117743,2YIVM@290174,4NG1D@976,COG2207@1,COG2207@2	NA|NA|NA	K	helix_turn_helix, arabinose operon control protein
MAG.T21.45_00275	938709.AUSH02000020_gene1989	1.4e-53	217.6	Bacteroidetes													Bacteria	4NTMP@976,COG1680@1,COG1680@2,COG5295@1,COG5295@2	NA|NA|NA	UW	COG1680 Beta-lactamase class C and other penicillin binding
MAG.T21.45_00277	760192.Halhy_5739	2.2e-77	298.1	Sphingobacteriia			3.2.1.4,5.2.1.8	ko:K01179,ko:K03768,ko:K08738,ko:K20276	ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko02024,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map02024,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko03110	3.D.4.6	GH5,GH9		Bacteria	1IQEG@117747,4NDZC@976,COG3209@1,COG3209@2,COG3291@1,COG3291@2	NA|NA|NA	P	C-terminal domain of CHU protein family
MAG.T21.45_00278	760192.Halhy_1038	7e-32	144.8	Bacteria													Bacteria	COG2885@1,COG2885@2	NA|NA|NA	M	chlorophyll binding
MAG.T21.45_00279	1123234.AUKI01000011_gene1102	1.5e-215	755.7	Flavobacteriia	sglT			ko:K03307					ko00000	2.A.21			Bacteria	1HXMU@117743,4NE9S@976,COG4146@1,COG4146@2	NA|NA|NA	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MAG.T21.45_00280	760192.Halhy_5879	4e-206	724.2	Sphingobacteriia	lpdA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1IQG6@117747,4NDVC@976,COG1249@1,COG1249@2	NA|NA|NA	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)
MAG.T21.45_00281	1122176.KB903554_gene3828	2e-68	265.8	Sphingobacteriia	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659	2.7.6.3,3.5.4.16	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R03503,R04639,R05046,R05048	RC00002,RC00017,RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv3609c	Bacteria	1IRE4@117747,4NFC2@976,COG0302@1,COG0302@2	NA|NA|NA	H	GTP cyclohydrolase 1
MAG.T21.45_00282	1267211.KI669560_gene2464	4.3e-79	301.2	Bacteria													Bacteria	COG4221@1,COG4221@2	NA|NA|NA	IQ	oxidoreductase activity
MAG.T21.45_00283	1122176.KB903548_gene1192	1.8e-26	127.1	Sphingobacteriia													Bacteria	1IWMV@117747,4NFPN@976,COG1470@1,COG1470@2	NA|NA|NA	S	Carboxypeptidase regulatory-like domain
MAG.T21.45_00284	700598.Niako_4543	1.7e-32	146.0	Sphingobacteriia	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71,4.2.3.4	ko:K00891,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000				Bacteria	1ITC4@117747,4NQ73@976,COG0703@1,COG0703@2	NA|NA|NA	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MAG.T21.45_00285	313606.M23134_00592	1.3e-150	540.0	Cytophagia			3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100		R01790,R01791,R06199		ko00000,ko00001,ko01000		GH15		Bacteria	47MRU@768503,4NEE6@976,COG3387@1,COG3387@2	NA|NA|NA	G	Glycosyl hydrolases family 15
MAG.T21.45_00286	760192.Halhy_5947	7.7e-32	143.7	Sphingobacteriia				ko:K20276	ko02024,map02024				ko00000,ko00001				Bacteria	1ITIS@117747,4NP5H@976,COG2885@1,COG2885@2	NA|NA|NA	M	Protein of unknown function (DUF1573)
MAG.T21.45_00287	760192.Halhy_6157	1.1e-23	115.9	Sphingobacteriia	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944		ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2			Bacteria	1IZTG@117747,4NUT4@976,COG1862@1,COG1862@2	NA|NA|NA	U	Preprotein translocase subunit
MAG.T21.45_00288	760192.Halhy_5221	6.9e-72	278.1	Bacteroidetes				ko:K02022,ko:K20345	ko02024,map02024				ko00000,ko00001,ko02000	3.A.1.112,8.A.1			Bacteria	4P48K@976,COG0845@1,COG0845@2	NA|NA|NA	M	HlyD family secretion protein
MAG.T21.45_00289	760192.Halhy_5220	3.3e-255	887.9	Sphingobacteriia				ko:K06147,ko:K20344	ko02010,ko02024,map02010,map02024				ko00000,ko00001,ko02000	3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21			Bacteria	1IPHA@117747,4NE19@976,COG2274@1,COG2274@2	NA|NA|NA	V	ABC transporter
MAG.T21.45_00290	761193.Runsl_1178	1e-52	213.8	Cytophagia	pldB		3.1.1.5	ko:K01048	ko00564,map00564				ko00000,ko00001,ko01000				Bacteria	47PWX@768503,4NIU9@976,COG2267@1,COG2267@2	NA|NA|NA	I	Serine aminopeptidase, S33
MAG.T21.45_00291	926556.Echvi_2450	1.4e-79	303.1	Cytophagia	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970		R03940	RC00026,RC00165	ko00000,ko00001,ko01000				Bacteria	47JDP@768503,4NE8U@976,COG0223@1,COG0223@2	NA|NA|NA	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MAG.T21.45_00292	1123057.P872_02745	1.2e-83	316.6	Cytophagia	fprA1		3.1.2.6	ko:K01069	ko00620,map00620		R01736	RC00004,RC00137	ko00000,ko00001,ko01000				Bacteria	47NQG@768503,4NHXR@976,COG0491@1,COG0491@2	NA|NA|NA	S	Metallo-beta-lactamase superfamily
MAG.T21.45_00294	983544.Lacal_1101	1.9e-73	283.5	Flavobacteriia	gsiA			ko:K02031,ko:K02032,ko:K12371,ko:K13892	ko02010,ko02024,map02010,map02024	M00239,M00324,M00348			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11			Bacteria	1HYRD@117743,4NGDP@976,COG1123@1,COG4172@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
MAG.T21.45_00295	760192.Halhy_6074	1.9e-87	329.7	Sphingobacteriia	rnd		3.1.13.5	ko:K03684					ko00000,ko01000,ko03016				Bacteria	1IZMJ@117747,4NP62@976,COG0349@1,COG0349@2	NA|NA|NA	L	3'-5' exonuclease
MAG.T21.45_00296	1122176.KB903538_gene1473	2.5e-67	264.2	Sphingobacteriia													Bacteria	1J0XT@117747,4PP25@976,COG2911@1,COG2911@2	NA|NA|NA	S	AsmA-like C-terminal region
MAG.T21.45_00297	760192.Halhy_6011	1.6e-307	1062.4	Sphingobacteriia	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944		ko:K03529,ko:K19171					ko00000,ko02048,ko03036				Bacteria	1IPD0@117747,4NHWQ@976,COG1196@1,COG1196@2	NA|NA|NA	D	Required for chromosome condensation and partitioning
MAG.T21.45_00298	760192.Halhy_6009	3.4e-118	431.8	Sphingobacteriia													Bacteria	1IW66@117747,4NJEQ@976,COG0520@1,COG0520@2	NA|NA|NA	E	Aminotransferase class-V
MAG.T21.45_00299	1250005.PHEL85_2237	2.9e-123	449.1	Polaribacter	glpD		1.1.5.3,2.7.1.30	ko:K00111,ko:K00864	ko00561,ko00564,ko01100,ko01110,ko03320,ko04626,map00561,map00564,map01100,map01110,map03320,map04626		R00847,R00848	RC00002,RC00017,RC00029	ko00000,ko00001,ko01000,ko04147				Bacteria	1IJMF@117743,3VW3V@52959,4PKIZ@976,COG0578@1,COG0578@2	NA|NA|NA	C	C-terminal domain of alpha-glycerophosphate oxidase
MAG.T21.45_00300	1382315.JPOI01000001_gene2845	1.2e-86	326.2	Geobacillus	glpF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02440					ko00000,ko02000	1.A.8.1,1.A.8.2			Bacteria	1TP4T@1239,1WF1X@129337,4HAWP@91061,COG0580@1,COG0580@2	NA|NA|NA	G	Belongs to the MIP aquaporin (TC 1.A.8) family
MAG.T21.45_00301	1120965.AUBV01000009_gene3018	4.4e-212	744.2	Cytophagia	pgi	GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147			iEcSMS35_1347.EcSMS35_4486	Bacteria	47JID@768503,4NDV0@976,COG0166@1,COG0166@2	NA|NA|NA	G	Belongs to the GPI family
MAG.T21.45_00302	1121904.ARBP01000002_gene7028	6.7e-22	111.3	Cytophagia													Bacteria	28JBH@1,2Z967@2,47PBF@768503,4NNHF@976	NA|NA|NA	S	Protein of unknown function (DUF3298)
MAG.T21.45_00303	760192.Halhy_6035	4.9e-276	956.8	Sphingobacteriia	acsA	GO:0003674,GO:0003824,GO:0003987,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006084,GO:0006085,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006473,GO:0006476,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016054,GO:0016405,GO:0016787,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018193,GO:0018205,GO:0018394,GO:0019213,GO:0019427,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033558,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034421,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045733,GO:0046390,GO:0046395,GO:0046483,GO:0050218,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072329,GO:0072521,GO:0072522,GO:0090407,GO:0098732,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004			iE2348C_1286.E2348C_4392,iYL1228.KPN_04478	Bacteria	1IPSM@117747,4NEAD@976,COG0365@1,COG0365@2	NA|NA|NA	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MAG.T21.45_00304	760192.Halhy_6034	8.8e-126	456.8	Sphingobacteriia													Bacteria	1IPSH@117747,28H6T@1,2Z7J4@2,4NE4C@976	NA|NA|NA		
MAG.T21.45_00305	760192.Halhy_6033	1.2e-85	323.6	Sphingobacteriia	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.80,2.8.1.11,3.1.2.6	ko:K01069,ko:K21029,ko:K21147	ko00620,ko04122,map00620,map04122		R01736,R07459,R07461	RC00004,RC00043,RC00137	ko00000,ko00001,ko01000				Bacteria	1IPBH@117747,4NFUD@976,COG0476@1,COG0476@2,COG0607@1,COG0607@2	NA|NA|NA	H	UBA THIF-type NAD FAD binding protein
MAG.T21.45_00306	1122176.KB903619_gene5389	6.1e-117	427.2	Sphingobacteriia	accD	GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000			iJN678.accD,iPC815.YPO2768,iUTI89_1310.UTI89_C2601	Bacteria	1IPMT@117747,4NFMH@976,COG0777@1,COG0777@2	NA|NA|NA	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MAG.T21.45_00307	1313421.JHBV01000030_gene2264	1.5e-114	419.5	Sphingobacteriia	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000			iPC815.YPO3734,iSBO_1134.SBO_4018	Bacteria	1INQH@117747,4NEQ7@976,COG0407@1,COG0407@2	NA|NA|NA	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MAG.T21.45_00308	760192.Halhy_5609	1.9e-60	238.8	Sphingobacteriia													Bacteria	1IY2W@117747,28H8R@1,2Z7KJ@2,4NGZN@976	NA|NA|NA		
MAG.T21.45_00309	760192.Halhy_5608	8.3e-137	493.8	Sphingobacteriia			1.1.98.6,1.8.1.9	ko:K00384,ko:K21636	ko00230,ko00240,ko00450,ko01100,map00230,map00240,map00450,map01100	M00053	R02016,R03596,R09372,R11633,R11634,R11635,R11636	RC00013,RC00613,RC02518,RC02873	ko00000,ko00001,ko00002,ko01000				Bacteria	1J0IU@117747,4PMB3@976,COG0526@1,COG0526@2	NA|NA|NA	CO	Redoxin
MAG.T21.45_00310	760192.Halhy_5607	1.6e-41	177.6	Sphingobacteriia	ydfG		1.1.1.276	ko:K05886					ko00000,ko01000				Bacteria	1INN2@117747,4NE1R@976,COG0457@1,COG0457@2,COG4221@1,COG4221@2	NA|NA|NA	NU	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAG.T21.45_00311	760192.Halhy_5607	2.5e-80	305.4	Sphingobacteriia	ydfG		1.1.1.276	ko:K05886					ko00000,ko01000				Bacteria	1INN2@117747,4NE1R@976,COG0457@1,COG0457@2,COG4221@1,COG4221@2	NA|NA|NA	NU	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAG.T21.45_00312	760192.Halhy_6369	4.5e-202	711.8	Bacteroidetes													Bacteria	4NEJ8@976,COG4447@1,COG4447@2	NA|NA|NA	O	M6 family metalloprotease domain protein
MAG.T21.45_00313	1122176.KB903538_gene1579	4.3e-59	234.2	Sphingobacteriia	ykhA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	3.1.2.20	ko:K01073					ko00000,ko01000				Bacteria	1IS80@117747,4NERA@976,COG1607@1,COG1607@2	NA|NA|NA	I	PFAM thioesterase superfamily
MAG.T21.45_00314	760192.Halhy_6372	1.5e-70	272.7	Sphingobacteriia	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181,2.8.1.8	ko:K03644,ko:K03801	ko00785,ko01100,map00785,map01100		R07766,R07767,R07768,R07769	RC00039,RC00992,RC01978,RC02867	ko00000,ko00001,ko01000				Bacteria	1INNH@117747,4NE14@976,COG0321@1,COG0321@2	NA|NA|NA	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate
MAG.T21.45_00316	984262.SGRA_1216	8.8e-42	177.2	Sphingobacteriia	mqnB	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.4.2.1,3.2.2.26,3.2.2.9	ko:K01243,ko:K03784,ko:K11783	ko00130,ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,ko01230,map00130,map00230,map00240,map00270,map00760,map01100,map01110,map01230	M00034,M00609	R00194,R01401,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R08587,R10244	RC00033,RC00063,RC00122,RC00318	ko00000,ko00001,ko00002,ko01000				Bacteria	1IT1C@117747,4NQVQ@976,COG0775@1,COG0775@2	NA|NA|NA	F	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)
MAG.T21.45_00317	706436.HMPREF9074_08664	1.1e-46	193.7	Capnocytophaga	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493			R10806	RC00003,RC03279	ko00000,ko01000,ko03012				Bacteria	1EQY3@1016,1HXBN@117743,4NDZB@976,COG2890@1,COG2890@2	NA|NA|NA	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MAG.T21.45_00318	760192.Halhy_6335	1e-130	473.4	Bacteroidetes	nspC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042401,GO:0042710,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044010,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044764,GO:0045312,GO:0046204,GO:0046983,GO:0048037,GO:0050662,GO:0051704,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100		R09081,R09082	RC00299	ko00000,ko00001,ko01000				Bacteria	4NEN0@976,COG0019@1,COG0019@2	NA|NA|NA	E	carboxynorspermidine decarboxylase
MAG.T21.45_00319	760192.Halhy_6334	1.3e-192	679.1	Bacteroidetes	LYS1		1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_0902	Bacteria	4NE0Y@976,COG1748@1,COG1748@2	NA|NA|NA	E	Saccharopine dehydrogenase
MAG.T21.45_00320	1122176.KB903531_gene2930	9.1e-48	198.0	Sphingobacteriia													Bacteria	1IZQC@117747,4NY6G@976,COG2244@1,COG2244@2	NA|NA|NA	S	Polysaccharide biosynthesis C-terminal domain
MAG.T21.45_00321	760192.Halhy_6326	5.7e-186	657.1	Sphingobacteriia	lys2		1.5.1.10,1.5.1.7	ko:K00290,ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R02315	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQ3W@117747,4NFM8@976,COG1748@1,COG1748@2	NA|NA|NA	E	Saccharopine dehydrogenase
MAG.T21.45_00322	760192.Halhy_6325	6.5e-36	157.1	Sphingobacteriia	cdd		2.4.2.2,3.5.4.5	ko:K00756,ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100		R01570,R01876,R01878,R02296,R02484,R02485,R08221	RC00063,RC00074,RC00514	ko00000,ko00001,ko01000				Bacteria	1ITF8@117747,4NQED@976,COG0295@1,COG0295@2	NA|NA|NA	F	cytidine and deoxycytidylate deaminase
MAG.T21.45_00324	760192.Halhy_6322	3.7e-49	201.8	Sphingobacteriia	kdsB		2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1IQQ6@117747,4NG4B@976,COG1212@1,COG1212@2	NA|NA|NA	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MAG.T21.45_00325	760192.Halhy_6321	1.3e-21	110.5	Sphingobacteriia	dotC	GO:0008150,GO:0009405,GO:0044419,GO:0051704	3.1.3.5,3.1.3.6,3.1.4.16,3.5.1.28,3.6.1.45,3.6.3.40	ko:K01119,ko:K01447,ko:K02040,ko:K02656,ko:K02666,ko:K07261,ko:K07273,ko:K08307,ko:K09693,ko:K11751,ko:K12204,ko:K14196,ko:K19223	ko00230,ko00240,ko00760,ko01100,ko01110,ko02010,ko02020,ko05150,ko05152,map00230,map00240,map00760,map01100,map01110,map02010,map02020,map05150,map05152	M00222,M00251	R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R04112,R05135	RC00017,RC00064,RC00078,RC00141,RC00296	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02000,ko02035,ko02044	3.A.1.104,3.A.1.7,3.A.15.2,3.A.7.10.1,3.A.7.9.1	CBM50		Bacteria	1ISAE@117747,4PFVG@976,COG1388@1,COG1388@2	NA|NA|NA	M	PFAM Peptidoglycan-binding lysin domain
MAG.T21.45_00326	1122176.KB903531_gene2913	7e-184	650.2	Sphingobacteriia	cysK		2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQU6@117747,4NDZ9@976,COG0031@1,COG0031@2	NA|NA|NA	E	Cystathionine beta-synthase
MAG.T21.45_00327	1123008.KB905692_gene208	7.8e-123	446.8	Porphyromonadaceae	aguB		3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100		R01152	RC00096	ko00000,ko00001,ko01000				Bacteria	22W1N@171551,2FMCZ@200643,4NEME@976,COG0388@1,COG0388@2	NA|NA|NA	S	Hydrolase, carbon-nitrogen family
MAG.T21.45_00328	760192.Halhy_0246	9.9e-106	390.2	Sphingobacteriia	aguA		3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100		R01416	RC00177	ko00000,ko00001,ko01000				Bacteria	1IP6F@117747,4NGF8@976,COG2957@1,COG2957@2	NA|NA|NA	E	Belongs to the agmatine deiminase family
MAG.T21.45_00329	760192.Halhy_0248	1.2e-206	726.5	Sphingobacteriia	ams		2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100		R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000		GH13		Bacteria	1IUZK@117747,4NI8U@976,COG0366@1,COG0366@2	NA|NA|NA	G	Alpha amylase, catalytic domain
MAG.T21.45_00330	760192.Halhy_5569	4.6e-83	314.7	Sphingobacteriia			3.4.14.13	ko:K20742,ko:K21471					ko00000,ko01000,ko01002,ko01011				Bacteria	1IRW3@117747,4NE2T@976,COG0791@1,COG0791@2	NA|NA|NA	M	PFAM NlpC P60 family
MAG.T21.45_00331	1122176.KB903531_gene2997	5.8e-72	278.1	Sphingobacteriia				ko:K06076					ko00000,ko02000	1.B.9			Bacteria	1IYCH@117747,4PN73@976,COG2067@1,COG2067@2	NA|NA|NA	I	Type IX secretion system membrane protein PorP/SprF
MAG.T21.45_00332	760192.Halhy_5567	8.8e-127	460.3	Sphingobacteriia	ribBA		3.5.4.25,4.1.99.12	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000				Bacteria	1INQM@117747,4NF6I@976,COG0108@1,COG0108@2,COG0807@1,COG0807@2	NA|NA|NA	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MAG.T21.45_00333	1122176.KB903554_gene3948	8.6e-66	257.7	Sphingobacteriia	sypQ												Bacteria	1J064@117747,4NN4F@976,COG1215@1,COG1215@2	NA|NA|NA	M	Glycosyltransferase like family 2
MAG.T21.45_00334	1122176.KB903554_gene3947	2.7e-81	309.3	Sphingobacteriia													Bacteria	1IR1Q@117747,4NFD3@976,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferases group 1
MAG.T21.45_00335	760192.Halhy_6493	1.3e-233	815.8	Sphingobacteriia			3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100		R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002				Bacteria	1IX27@117747,4NEXH@976,COG0308@1,COG0308@2	NA|NA|NA	E	Peptidase family M1 domain
MAG.T21.45_00336	760192.Halhy_1731	2.6e-34	152.1	Sphingobacteriia													Bacteria	1ITRI@117747,2CBKC@1,32RTJ@2,4NTE7@976	NA|NA|NA		
MAG.T21.45_00338	1122176.KB903538_gene1562	1.9e-275	954.9	Sphingobacteriia	dnaK	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141		ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152				ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1			Bacteria	1IPCI@117747,4NERF@976,COG0443@1,COG0443@2	NA|NA|NA	O	Heat shock 70 kDa protein
MAG.T21.45_00339	760192.Halhy_6179	1.4e-43	183.7	Bacteroidetes													Bacteria	2CA1R@1,3391I@2,4NXBJ@976	NA|NA|NA		
MAG.T21.45_00340	760192.Halhy_6177	1.1e-91	343.6	Sphingobacteriia	mltG			ko:K07082					ko00000				Bacteria	1IP2P@117747,4NG17@976,COG1559@1,COG1559@2	NA|NA|NA	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MAG.T21.45_00341	760192.Halhy_2716	1.5e-103	382.9	Sphingobacteriia	ddl		6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502		R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	1INQY@117747,4NE9P@976,COG1181@1,COG1181@2	NA|NA|NA	F	Belongs to the D-alanine--D-alanine ligase family
MAG.T21.45_00343	760192.Halhy_6132	2e-11	75.9	Bacteria	thiE		2.5.1.3,2.7.6.2,5.4.2.6	ko:K00788,ko:K00949,ko:K01838,ko:K07025	ko00500,ko00730,ko01100,map00500,map00730,map01100	M00127	R00619,R02728,R03223,R10712,R11310	RC00002,RC00017,RC00224,RC00408,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000				Bacteria	COG0637@1,COG0637@2	NA|NA|NA	S	phosphonoacetaldehyde hydrolase activity
MAG.T21.45_00344	760192.Halhy_6133	6.7e-149	534.3	Sphingobacteriia													Bacteria	1IQIN@117747,4NHSB@976,COG5267@1,COG5267@2	NA|NA|NA	S	Protein of unknown function (DUF1800)
MAG.T21.45_00345	760192.Halhy_6134	1.4e-146	526.6	Sphingobacteriia													Bacteria	1IPWT@117747,4NFFC@976,COG4102@1,COG4102@2	NA|NA|NA	S	Protein of unknown function (DUF1501)
MAG.T21.45_00346	760192.Halhy_2649	5.2e-114	417.9	Sphingobacteriia	anmK		2.7.1.170,4.2.1.126	ko:K07106,ko:K09001	ko00520,ko01100,map00520,map01100		R08555	RC00397,RC00746	ko00000,ko00001,ko01000				Bacteria	1IPA4@117747,4NFZU@976,COG2377@1,COG2377@2	NA|NA|NA	H	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MAG.T21.45_00347	760192.Halhy_0848	2.4e-27	128.6	Sphingobacteriia	CP_0160												Bacteria	1IT29@117747,4NNKI@976,COG4096@1,COG4096@2	NA|NA|NA	L	PFAM Restriction endonuclease, type I, EcoRI, R subunit Type III, Res subunit, N-terminal
MAG.T21.45_00349	760192.Halhy_0845	4.5e-69	268.9	Sphingobacteriia	tilS		6.3.4.19	ko:K04075			R09597	RC02633,RC02634	ko00000,ko01000,ko03016				Bacteria	1IQ7X@117747,4NEJS@976,COG0037@1,COG0037@2	NA|NA|NA	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MAG.T21.45_00350	760192.Halhy_6149	5.9e-100	371.3	Sphingobacteriia	lysC		1.1.1.3,2.7.2.4	ko:K00928,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQ3C@117747,4NF0M@976,COG0527@1,COG0527@2	NA|NA|NA	E	Belongs to the aspartokinase family
MAG.T21.45_00351	760192.Halhy_6148	2e-185	655.6	Sphingobacteriia			6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100		R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029				Bacteria	1IW1A@117747,4NF8C@976,COG0154@1,COG0154@2	NA|NA|NA	J	Amidase
MAG.T21.45_00352	1121889.AUDM01000022_gene508	8.1e-123	447.2	Flavobacterium	yhiN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464		ko:K07007					ko00000				Bacteria	1HWY6@117743,2NSIQ@237,4NFME@976,COG2081@1,COG2081@2	NA|NA|NA	S	flavoprotein
MAG.T21.45_00353	760192.Halhy_5877	1.3e-69	269.6	Sphingobacteriia	rluC		5.4.99.23	ko:K06180					ko00000,ko01000,ko03009				Bacteria	1IR96@117747,4NFS8@976,COG0564@1,COG0564@2	NA|NA|NA	J	PFAM Pseudouridine synthase, RsuA and RluB C D E F
MAG.T21.45_00354	1313421.JHBV01000005_gene4613	4.4e-88	331.3	Sphingobacteriia	mqnD			ko:K07083,ko:K11785	ko00130,ko01110,map00130,map01110		R08589	RC02330	ko00000,ko00001,ko01000				Bacteria	1INXU@117747,4NFAN@976,COG2107@1,COG2107@2	NA|NA|NA	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
MAG.T21.45_00355	1410668.JNKC01000004_gene302	1.3e-32	146.7	Clostridiaceae	yjjG	GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006206,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008655,GO:0009058,GO:0009112,GO:0009410,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019856,GO:0019859,GO:0030145,GO:0034641,GO:0034654,GO:0042221,GO:0042578,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.1.3.102,3.1.3.104,3.1.3.5,3.8.1.2	ko:K01560,ko:K07025,ko:K08723,ko:K20862	ko00230,ko00240,ko00361,ko00625,ko00740,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00740,map00760,map01100,map01110,map01120	M00125	R00183,R00511,R00548,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287,R07280	RC00017,RC00697	ko00000,ko00001,ko00002,ko01000			iECNA114_1301.ECNA114_4614	Bacteria	1TRQ6@1239,25B04@186801,36WB0@31979,COG1011@1,COG1011@2	NA|NA|NA	S	HAD superfamily (Subfamily IA) hydrolase, TIGR02254
MAG.T21.45_00356	1166018.FAES_1598	3.5e-157	561.2	Cytophagia	ald		1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100		R00396	RC00008	ko00000,ko00001,ko01000				Bacteria	47K8G@768503,4NE8F@976,COG0686@1,COG0686@2	NA|NA|NA	E	Belongs to the AlaDH PNT family
MAG.T21.45_00357	760192.Halhy_5399	3.8e-95	356.3	Bacteroidetes													Bacteria	4PKDV@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.45_00358	118168.MC7420_1742	1.1e-38	167.2	Oscillatoriales	ycbX	GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009636,GO:0009987,GO:0019748,GO:0042221,GO:0044237,GO:0044248,GO:0050896,GO:0098754		ko:K07140					ko00000				Bacteria	1G41J@1117,1HA5C@1150,COG3217@1,COG3217@2	NA|NA|NA	S	Fe-S protein
MAG.T21.45_00359	1313421.JHBV01000034_gene1698	8.8e-79	300.4	Sphingobacteriia	ubiA		2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006				Bacteria	1IP3B@117747,4NEE3@976,COG0382@1,COG0382@2	NA|NA|NA	H	4-hydroxybenzoate polyprenyltransferase
MAG.T21.45_00360	760192.Halhy_5397	3.9e-36	157.9	Bacteroidetes				ko:K20276	ko02024,map02024				ko00000,ko00001				Bacteria	4NP5H@976,COG2885@1,COG2885@2	NA|NA|NA	M	InterPro IPR011467
MAG.T21.45_00361	760192.Halhy_5396	7.4e-143	514.2	Sphingobacteriia	polX			ko:K02347,ko:K04477					ko00000,ko03400				Bacteria	1IPE5@117747,4NDX5@976,COG1387@1,COG1387@2,COG1796@1,COG1796@2	NA|NA|NA	L	DNA polymerase
MAG.T21.45_00362	760192.Halhy_1121	3.9e-30	137.9	Sphingobacteriia			5.2.1.8	ko:K03772					ko00000,ko01000,ko03110				Bacteria	1ITE9@117747,4NQJS@976,COG0545@1,COG0545@2	NA|NA|NA	O	COGs COG0545 FKBP-type peptidyl-prolyl cis-trans isomerase 1
MAG.T21.45_00363	1122179.KB890415_gene1948	3.2e-29	134.4	Sphingobacteriia			2.7.11.1,4.6.1.1	ko:K01768,ko:K12132	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001				Bacteria	1ISVX@117747,4NSNP@976,COG4191@1,COG4191@2	NA|NA|NA	T	Protein of unknown function (DUF3467)
MAG.T21.45_00364	760192.Halhy_5393	0.0	1133.2	Sphingobacteriia	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168					ko00000,ko01000,ko03032,ko03400				Bacteria	1IPJD@117747,4NF9S@976,COG0550@1,COG0550@2,COG1754@1,COG1754@2	NA|NA|NA	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MAG.T21.45_00365	760192.Halhy_5392	1.9e-142	512.3	Bacteria				ko:K06873					ko00000				Bacteria	COG0857@1,COG0857@2	NA|NA|NA	C	belongs to the CobB CobQ family
MAG.T21.45_00366	760192.Halhy_5391	5.4e-160	570.9	Sphingobacteriia	purB	GO:0003674,GO:0003824,GO:0004018,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000			iAF1260.b1131,iBWG_1329.BWG_0979,iE2348C_1286.E2348C_1272,iEC042_1314.EC042_1202,iECABU_c1320.ECABU_c13450,iECDH10B_1368.ECDH10B_1203,iECP_1309.ECP_1126,iECUMN_1333.ECUMN_1375,iETEC_1333.ETEC_1255,iEcHS_1320.EcHS_A1251,iEcolC_1368.EcolC_2472,iJO1366.b1131,iJR904.b1131,iLF82_1304.LF82_1774,iNRG857_1313.NRG857_05460,iY75_1357.Y75_RS05905,ic_1306.c1510	Bacteria	1IPIU@117747,4NFY8@976,COG0015@1,COG0015@2	NA|NA|NA	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MAG.T21.45_00367	866536.Belba_2918	9.8e-269	932.6	Cytophagia				ko:K06978					ko00000				Bacteria	47JKV@768503,4NFFB@976,COG2936@1,COG2936@2	NA|NA|NA	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain
MAG.T21.45_00368	760192.Halhy_6373	4.4e-73	282.0	Sphingobacteriia	yqfF			ko:K07037					ko00000				Bacteria	1IPKB@117747,4NEHV@976,COG1480@1,COG1480@2	NA|NA|NA	S	7TM receptor with intracellular HD hydrolase
MAG.T21.45_00370	760192.Halhy_6380	5.2e-45	187.6	Sphingobacteriia	yvqK	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.2.1.88,1.5.5.2,2.5.1.17	ko:K00798,ko:K13821	ko00250,ko00330,ko00860,ko01100,ko01110,ko01130,map00250,map00330,map00860,map01100,map01110,map01130	M00122	R00245,R00707,R00708,R01253,R01492,R04444,R04445,R05051,R05220,R07268	RC00080,RC00083,RC00216,RC00242,RC00255,RC00533	ko00000,ko00001,ko00002,ko01000,ko03000				Bacteria	1IRY6@117747,4NFHQ@976,COG2096@1,COG2096@2	NA|NA|NA	S	Cobalamin adenosyltransferase
MAG.T21.45_00371	760192.Halhy_6066	1.2e-97	362.8	Sphingobacteriia	macB			ko:K02003		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1IQ8R@117747,4NE5N@976,COG1136@1,COG1136@2	NA|NA|NA	V	ABC transporter
MAG.T21.45_00372	760192.Halhy_6065	4.7e-16	90.5	Sphingobacteriia	gatC		6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100		R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029			iAF987.Gmet_0076	Bacteria	1ITUB@117747,4NV0A@976,COG0721@1,COG0721@2	NA|NA|NA	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MAG.T21.45_00373	1122176.KB903531_gene3008	3.2e-87	328.2	Sphingobacteriia	dck												Bacteria	1INU0@117747,4NFA8@976,COG1428@1,COG1428@2	NA|NA|NA	F	deoxynucleoside kinase
MAG.T21.45_00374	1313421.JHBV01000029_gene1862	2.2e-53	215.7	Sphingobacteriia	yggS			ko:K06997					ko00000				Bacteria	1INT9@117747,4NE42@976,COG0325@1,COG0325@2	NA|NA|NA	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MAG.T21.45_00375	760192.Halhy_0457	7.3e-105	387.5	Sphingobacteriia			3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147				Bacteria	1IPXF@117747,4NG3D@976,COG1785@1,COG1785@2	NA|NA|NA	P	Belongs to the alkaline phosphatase family
MAG.T21.45_00376	760192.Halhy_5315	3.3e-206	724.5	Sphingobacteriia	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626		R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147				Bacteria	1IP31@117747,4NFUH@976,COG0554@1,COG0554@2	NA|NA|NA	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MAG.T21.45_00377	760192.Halhy_5314	2.9e-152	545.4	Sphingobacteriia	bshC			ko:K22136					ko00000				Bacteria	1IP68@117747,4NGCF@976,COG4365@1,COG4365@2	NA|NA|NA	S	Belongs to the BshC family
MAG.T21.45_00378	760192.Halhy_0692	4.6e-280	970.7	Sphingobacteriia				ko:K14054					ko00000				Bacteria	1IVSM@117747,4NEJA@976,COG2866@1,COG2866@2	NA|NA|NA	E	Zinc carboxypeptidase
MAG.T21.45_00379	760192.Halhy_0693	4.1e-179	634.4	Sphingobacteriia													Bacteria	1IPRF@117747,4NENF@976,COG2234@1,COG2234@2	NA|NA|NA	S	Peptidase family M28
MAG.T21.45_00380	760192.Halhy_6351	1.6e-255	889.0	Sphingobacteriia	penA		3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130		R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002				Bacteria	1IPU7@117747,4NEIX@976,COG2366@1,COG2366@2	NA|NA|NA	S	COG2366 Protein related to penicillin acylase
MAG.T21.45_00381	1122176.KB903619_gene5293	2e-123	449.1	Bacteria													Bacteria	COG4663@1,COG4663@2	NA|NA|NA	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MAG.T21.45_00382	1122176.KB903538_gene1458	6.2e-153	547.4	Bacteroidetes	dctM			ko:K03299					ko00000,ko02000	2.A.8			Bacteria	4PM5T@976,COG4664@1,COG4664@2	NA|NA|NA	Q	Tripartite ATP-independent periplasmic transporter, DctM component
MAG.T21.45_00383	639282.DEFDS_2070	1.8e-31	142.5	Deferribacteres													Bacteria	2GFRG@200930,COG4665@1,COG4665@2	NA|NA|NA	Q	Tripartite ATP-independent Periplasmic Transporter
MAG.T21.45_00384	760192.Halhy_0347	1.2e-129	469.5	Sphingobacteriia	prfB	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02836					ko00000,ko03012				Bacteria	1IP7G@117747,4NEN1@976,COG1186@1,COG1186@2	NA|NA|NA	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MAG.T21.45_00385	1122179.KB890438_gene1562	1.6e-32	146.7	Sphingobacteriia			5.2.1.8	ko:K03772					ko00000,ko01000,ko03110				Bacteria	1IQ1U@117747,4NDW4@976,COG0545@1,COG0545@2	NA|NA|NA	O	PFAM FKBP-type peptidyl-prolyl cis-trans isomerase
MAG.T21.45_00386	1122176.KB903554_gene3832	5.9e-111	407.5	Sphingobacteriia	nrnA	GO:0008150,GO:0040007	2.7.7.72,3.1.13.3,3.1.3.7	ko:K00974,ko:K06881	ko00920,ko01100,ko01120,ko03013,map00920,map01100,map01120,map03013		R00188,R00508,R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03400				Bacteria	1IPG0@117747,4NEXE@976,COG0618@1,COG0618@2	NA|NA|NA	S	phosphoesterase RecJ domain protein
MAG.T21.45_00393	643867.Ftrac_1144	8.8e-21	107.5	Cytophagia													Bacteria	47RZ2@768503,4NMZ9@976,COG3714@1,COG3714@2	NA|NA|NA	S	PFAM YhhN-like protein
MAG.T21.45_00394	760192.Halhy_1859	1.8e-72	279.3	Sphingobacteriia	trmH		2.1.1.185,2.1.1.34	ko:K00556,ko:K03218,ko:K03437					ko00000,ko01000,ko03009,ko03016				Bacteria	1IRFD@117747,4NF6H@976,COG0566@1,COG0566@2	NA|NA|NA	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MAG.T21.45_00395	1123277.KB893175_gene1408	2.2e-240	838.2	Cytophagia	pnbA			ko:K03929					ko00000,ko01000		CE10		Bacteria	47JGD@768503,4NG5B@976,COG2272@1,COG2272@2	NA|NA|NA	I	Belongs to the type-B carboxylesterase lipase family
MAG.T21.45_00396	760192.Halhy_1860	8.1e-256	890.6	Sphingobacteriia				ko:K20276	ko02024,map02024				ko00000,ko00001				Bacteria	1IWTI@117747,4PM4A@976,COG4412@1,COG4412@2	NA|NA|NA	UW	Fungalysin metallopeptidase (M36)
MAG.T21.45_00397	760192.Halhy_1844	1.7e-20	105.5	Sphingobacteriia	folB		1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8	ko:K00796,ko:K00950,ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503,R03504,R11037,R11073	RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000				Bacteria	1ITVJ@117747,4NQ53@976,COG1539@1,COG1539@2	NA|NA|NA	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MAG.T21.45_00398	1267211.KI669560_gene614	7.3e-42	177.2	Bacteria				ko:K06976					ko00000				Bacteria	COG3393@1,COG3393@2	NA|NA|NA	S	Acetyltransferase (GNAT) family
MAG.T21.45_00399	760192.Halhy_1845	1.1e-191	676.0	Sphingobacteriia	gcdH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000				Bacteria	1INZ7@117747,4NEKJ@976,COG1960@1,COG1960@2	NA|NA|NA	I	acyl-CoA dehydrogenase
MAG.T21.45_00400	760192.Halhy_1846	6.6e-101	374.4	Bacteria													Bacteria	COG2885@1,COG2885@2	NA|NA|NA	M	chlorophyll binding
MAG.T21.45_00402	1122176.KB903557_gene4034	2.2e-131	475.7	Sphingobacteriia	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQJK@117747,4NE8T@976,COG0128@1,COG0128@2	NA|NA|NA	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MAG.T21.45_00403	487796.Flav2ADRAFT_0215	3.6e-38	164.5	Flavobacteriia	osmC			ko:K07397					ko00000				Bacteria	1I2VB@117743,4NQ66@976,COG1765@1,COG1765@2	NA|NA|NA	O	redox protein regulator of disulfide bond formation
MAG.T21.45_00404	760192.Halhy_3794	9.1e-126	456.8	Sphingobacteriia	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K06217					ko00000				Bacteria	1INQV@117747,4NDYV@976,COG1702@1,COG1702@2	NA|NA|NA	T	Phosphate starvation-inducible protein PhoH
MAG.T21.45_00405	760192.Halhy_3793	1.1e-53	216.9	Sphingobacteriia	fjo14			ko:K22205					ko00000,ko01000				Bacteria	1IQEU@117747,4NG9Y@976,COG1912@1,COG1912@2	NA|NA|NA	S	S-adenosyl-l-methionine hydroxide adenosyltransferase
MAG.T21.45_00406	760192.Halhy_3620	2.1e-98	365.9	Sphingobacteriia	aroB		2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQ2Q@117747,4NGSS@976,COG0337@1,COG0337@2	NA|NA|NA	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MAG.T21.45_00407	760192.Halhy_3619	2.4e-265	921.8	Sphingobacteriia	mrcA		2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501				ko00000,ko00001,ko01000,ko01003,ko01011		GT51		Bacteria	1IQ85@117747,4NECJ@976,COG5009@1,COG5009@2	NA|NA|NA	M	PFAM Penicillin binding protein transpeptidase domain
MAG.T21.45_00408	760192.Halhy_3618	1.4e-138	500.4	Sphingobacteriia			5.2.1.8	ko:K01802,ko:K03768					ko00000,ko01000,ko03110				Bacteria	1IZ2E@117747,4PIRV@976,COG0652@1,COG0652@2,COG1413@1,COG1413@2	NA|NA|NA	CO	E-Z type HEAT repeats
MAG.T21.45_00409	760192.Halhy_3617	1.7e-135	489.2	Sphingobacteriia	gcvT		2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPCZ@117747,4NF7S@976,COG0404@1,COG0404@2	NA|NA|NA	E	The glycine cleavage system catalyzes the degradation of glycine
MAG.T21.45_00410	760192.Halhy_3616	4.5e-51	207.6	Sphingobacteriia													Bacteria	1ISGU@117747,4NQPD@976,COG1510@1,COG1510@2	NA|NA|NA	K	Belongs to the GbsR family
MAG.T21.45_00411	760192.Halhy_3615	7.3e-122	443.7	Sphingobacteriia			1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1IV68@117747,4NDVN@976,COG0111@1,COG0111@2	NA|NA|NA	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MAG.T21.45_00413	760192.Halhy_2212	5.4e-32	144.4	Bacteria	cvpA			ko:K03558					ko00000				Bacteria	COG1286@1,COG1286@2	NA|NA|NA	S	toxin biosynthetic process
MAG.T21.45_00414	760192.Halhy_1858	6.7e-67	260.8	Bacteria													Bacteria	COG2932@1,COG2932@2	NA|NA|NA	K	sequence-specific DNA binding
MAG.T21.45_00415	760192.Halhy_1857	3.2e-283	981.1	Sphingobacteriia	ftsK			ko:K03466					ko00000,ko03036	3.A.12			Bacteria	1INVI@117747,4NE86@976,COG1674@1,COG1674@2	NA|NA|NA	D	DNA segregation ATPase FtsK SpoIIIE and related
MAG.T21.45_00416	1185876.BN8_03136	9.4e-102	376.7	Cytophagia													Bacteria	47JFN@768503,4NES7@976,COG3000@1,COG3000@2	NA|NA|NA	I	Fatty acid hydroxylase superfamily
MAG.T21.45_00417	760192.Halhy_2938	1.5e-226	792.0	Sphingobacteriia	trpB		4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000				Bacteria	1IVN5@117747,4PKSY@976,COG1350@1,COG1350@2	NA|NA|NA	E	Pyridoxal-phosphate dependent enzyme
MAG.T21.45_00418	929703.KE386491_gene582	1.8e-52	213.0	Cytophagia				ko:K15270					ko00000,ko02000	2.A.7.3.7			Bacteria	47KBM@768503,4NDYH@976,COG0697@1,COG0697@2	NA|NA|NA	EG	PFAM EamA-like transporter family
MAG.T21.45_00419	760192.Halhy_0063	4.4e-131	474.9	Sphingobacteriia	MA20_40030												Bacteria	1J075@117747,4PM59@976,COG4784@1,COG4784@2	NA|NA|NA	S	Peptidase family M48
MAG.T21.45_00421	1121481.AUAS01000003_gene3785	1.2e-53	216.9	Cytophagia	coaX		2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	47K5B@768503,4NE9E@976,COG1521@1,COG1521@2	NA|NA|NA	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MAG.T21.45_00422	945713.IALB_1028	3.3e-52	212.6	Bacteria													Bacteria	28KFX@1,2ZA1W@2	NA|NA|NA		
MAG.T21.45_00423	1120968.AUBX01000010_gene995	6.2e-104	384.0	Cytophagia	yqfU												Bacteria	47JNV@768503,4NG9F@976,COG1284@1,COG1284@2	NA|NA|NA	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MAG.T21.45_00424	391598.FBBAL38_11469	1.7e-53	217.2	Flavobacteriia													Bacteria	1I4NQ@117743,4NTMP@976,COG4704@1,COG4704@2,COG5295@1,COG5295@2	NA|NA|NA	UW	Hep Hag repeat protein
MAG.T21.45_00425	760192.Halhy_4282	4e-131	474.9	Sphingobacteriia	lysC	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009090,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.3,2.7.2.4,4.1.1.20	ko:K00928,ko:K12524,ko:K12526	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00451,R00480,R01773,R01775	RC00002,RC00043,RC00087,RC00299	ko00000,ko00001,ko00002,ko01000			iECED1_1282.ECED1_4739,iPC815.YPO3719	Bacteria	1IPZ7@117747,4NFWR@976,COG0527@1,COG0527@2	NA|NA|NA	E	Belongs to the aspartokinase family
MAG.T21.45_00426	760192.Halhy_4281	1.7e-53	216.1	Bacteroidetes													Bacteria	4NJDY@976,COG0527@1,COG0527@2	NA|NA|NA	E	aspartate kinase activity
MAG.T21.45_00427	760192.Halhy_4235	1.1e-64	253.4	Sphingobacteriia													Bacteria	1IPGU@117747,4NGJR@976,COG0697@1,COG0697@2	NA|NA|NA	EG	PFAM EamA-like transporter family
MAG.T21.45_00428	760192.Halhy_2523	5.8e-44	184.5	Sphingobacteriia	dksA			ko:K06204	ko02026,map02026				ko00000,ko00001,ko03000,ko03009,ko03021				Bacteria	1IZ4X@117747,4NNID@976,COG1734@1,COG1734@2	NA|NA|NA	T	Molecular chaperone DnaK
MAG.T21.45_00429	760192.Halhy_2525	6.6e-247	859.8	Sphingobacteriia	yhcX		3.5.1.3	ko:K11206,ko:K13566	ko00250,map00250		R00269,R00348	RC00010	ko00000,ko00001,ko01000				Bacteria	1IPV0@117747,4NEAQ@976,COG0388@1,COG0388@2	NA|NA|NA	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MAG.T21.45_00430	1121373.KB903664_gene2590	8.4e-45	187.2	Cytophagia													Bacteria	47JTK@768503,4NGVV@976,COG0745@1,COG0745@2	NA|NA|NA	T	PFAM response regulator receiver
MAG.T21.45_00432	760192.Halhy_4058	3.3e-195	688.0	Bacteroidetes													Bacteria	4NH5R@976,COG0189@1,COG0189@2	NA|NA|NA	HJ	ligase activity
MAG.T21.45_00433	760568.Desku_2705	2.8e-13	82.4	Peptococcaceae	degU			ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	M00478			ko00000,ko00001,ko00002,ko02022				Bacteria	1TRXG@1239,24FZX@186801,266S4@186807,COG2197@1,COG2197@2	NA|NA|NA	K	response regulator receiver
MAG.T21.45_00434	1550091.JROE01000006_gene2666	7.6e-32	144.1	Sphingobacteriia													Bacteria	1IT9D@117747,4NF5P@976,COG2197@1,COG2197@2	NA|NA|NA	T	helix_turn_helix, Lux Regulon
MAG.T21.45_00435	641526.ADIWIN_0759	1.3e-49	205.3	Flavobacteriia													Bacteria	1HXPR@117743,4NHSC@976,COG3292@1,COG3292@2,COG4585@1,COG4585@2	NA|NA|NA	T	Histidine kinase
MAG.T21.45_00436	755732.Fluta_3353	9.7e-39	168.7	Bacteroidetes													Bacteria	4PKDT@976,COG5184@1,COG5184@2	NA|NA|NA	DZ	M6 family metalloprotease domain protein
MAG.T21.45_00437	485918.Cpin_3623	0.0	1932.9	Sphingobacteriia	pelX			ko:K20276	ko02024,map02024				ko00000,ko00001				Bacteria	1J0N1@117747,4PKBQ@976,COG2304@1,COG2304@2,COG2373@1,COG2373@2,COG2755@1,COG2755@2,COG3209@1,COG3209@2,COG5492@1,COG5492@2	NA|NA|NA	M	conserved repeat domain protein
MAG.T21.45_00438	1120966.AUBU01000013_gene440	2.5e-10	72.8	Bacteroidetes													Bacteria	4NVT9@976,COG2207@1,COG2207@2	NA|NA|NA	K	Helix-turn-helix domain
MAG.T21.45_00439	1122176.KB903549_gene1241	1e-45	189.5	Sphingobacteriia	moaE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122		R09395	RC02507	ko00000,ko00001,ko01000				Bacteria	1ITHC@117747,4NP1X@976,COG0314@1,COG0314@2	NA|NA|NA	H	Molybdopterin converting factor, large subunit
MAG.T21.45_00440	760192.Halhy_2050	7.2e-125	454.5	Sphingobacteriia	algI			ko:K19294					ko00000				Bacteria	1IR85@117747,4NFK5@976,COG1696@1,COG1696@2	NA|NA|NA	M	PFAM membrane bound O-acyl transferase MBOAT
MAG.T21.45_00441	760192.Halhy_3222	2.2e-79	303.1	Sphingobacteriia	Z012_00180		3.1.1.5	ko:K10804	ko01040,map01040				ko00000,ko00001,ko01000,ko01004				Bacteria	1IRWS@117747,4NK39@976,COG2755@1,COG2755@2	NA|NA|NA	E	COG2755 Lysophospholipase L1 and related esterases
MAG.T21.45_00442	760192.Halhy_4238	1.7e-75	289.3	Sphingobacteriia	ygdL	GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0030955,GO:0031402,GO:0031420,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.7.7.73,2.7.7.80	ko:K03148,ko:K21029,ko:K22132	ko00730,ko01100,ko04122,map00730,map01100,map04122		R07459	RC00043	ko00000,ko00001,ko01000,ko03016				Bacteria	1IRVV@117747,4NEKB@976,COG1179@1,COG1179@2	NA|NA|NA	H	UBA THIF-type NAD FAD binding
MAG.T21.45_00443	382464.ABSI01000011_gene2956	1.7e-14	85.5	Verrucomicrobia	M1-746												Bacteria	46WGW@74201,COG4818@1,COG4818@2	NA|NA|NA	S	TM2 domain
MAG.T21.45_00444	1120968.AUBX01000018_gene2072	4.2e-180	637.9	Cytophagia			3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000				Bacteria	47KC3@768503,4NHDD@976,COG3653@1,COG3653@2	NA|NA|NA	Q	PFAM D-aminoacylase, C-terminal region
MAG.T21.45_00445	1305737.JAFX01000001_gene2452	5.3e-199	701.0	Cytophagia													Bacteria	47NS1@768503,4NFTM@976,COG0823@1,COG0823@2,COG1506@1,COG1506@2	NA|NA|NA	EU	Dienelactone hydrolase family
MAG.T21.45_00446	714943.Mucpa_2712	7.5e-69	268.1	Sphingobacteriia													Bacteria	1IR3E@117747,4NJZJ@976,COG4299@1,COG4299@2	NA|NA|NA	S	Domain of unknown function (DUF5009)
MAG.T21.45_00448	388413.ALPR1_11190	6.2e-194	683.7	Cytophagia													Bacteria	47JNX@768503,4NEN5@976,COG0673@1,COG0673@2	NA|NA|NA	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_00449	694427.Palpr_0321	2.2e-147	528.9	Porphyromonadaceae	rhlE		3.6.4.13	ko:K11927	ko03018,map03018				ko00000,ko00001,ko01000,ko03019				Bacteria	22W9M@171551,2FM7Y@200643,4NEVI@976,COG0513@1,COG0513@2	NA|NA|NA	L	Belongs to the DEAD box helicase family
MAG.T21.45_00450	1124780.ANNU01000069_gene1099	5.7e-63	247.3	Cytophagia				ko:K09939					ko00000				Bacteria	47PX8@768503,4NIXJ@976,COG3182@1,COG3182@2	NA|NA|NA	S	PepSY-associated TM region
MAG.T21.45_00451	760192.Halhy_6450	1.5e-140	506.1	Sphingobacteriia													Bacteria	1ISPB@117747,4NGZR@976,COG1680@1,COG1680@2	NA|NA|NA	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein
MAG.T21.45_00452	760192.Halhy_0703	7.6e-54	216.9	Sphingobacteriia	Z012_04670												Bacteria	1IXNR@117747,4NP61@976,COG3182@1,COG3182@2	NA|NA|NA	S	membrane
MAG.T21.45_00453	760192.Halhy_2387	2.6e-49	204.5	Bacteroidetes	gshF		2.7.11.1,6.3.2.2,6.3.2.29,6.3.2.30,6.3.2.4,6.3.5.5	ko:K01919,ko:K01921,ko:K01955,ko:K03802,ko:K12132,ko:K16181,ko:K16786,ko:K16787	ko00240,ko00250,ko00270,ko00300,ko00473,ko00480,ko00550,ko01100,ko01120,ko01502,ko02010,map00240,map00250,map00270,map00300,map00473,map00480,map00550,map01100,map01120,map01502,map02010	M00051,M00118,M00582	R00256,R00575,R00894,R01150,R01395,R10011,R10948,R10949,R10993	RC00002,RC00010,RC00043,RC00064,RC00090,RC00096,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01001,ko01011,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	4NSUI@976,COG1181@1,COG1181@2,COG2815@1,COG2815@2	NA|NA|NA	M	Pasta domain
MAG.T21.45_00454	760192.Halhy_2388	2.6e-249	869.0	Bacteroidetes													Bacteria	4NEN7@976,COG4935@1,COG4935@2	NA|NA|NA	O	Pfam Proprotein convertase
MAG.T21.45_00455	760192.Halhy_2342	1.6e-195	690.3	Sphingobacteriia													Bacteria	1IRMG@117747,4PKQ9@976,COG3536@1,COG3536@2	NA|NA|NA	S	Protein conserved in bacteria
MAG.T21.45_00456	1122176.KB903569_gene3479	6.3e-182	644.8	Bacteroidetes			1.11.1.7,1.6.3.1	ko:K03931,ko:K13411,ko:K15125,ko:K19511	ko04013,ko04624,ko05133,map04013,map04624,map05133				ko00000,ko00001,ko00536,ko01000,ko04131	5.B.1.2	GH63		Bacteria	4NIKN@976,COG2931@1,COG2931@2,COG3210@1,COG3210@2	NA|NA|NA	Q	Animal haem peroxidase
MAG.T21.45_00457	760192.Halhy_3858	5.2e-231	807.4	Sphingobacteriia	fadH	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008670,GO:0009056,GO:0009062,GO:0009987,GO:0010181,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0016628,GO:0019395,GO:0019752,GO:0030258,GO:0032553,GO:0032787,GO:0033542,GO:0033543,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071949,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901575	1.3.1.34	ko:K00219					ko00000,ko01000				Bacteria	1IQZ0@117747,4NF98@976,COG0446@1,COG0446@2,COG1902@1,COG1902@2	NA|NA|NA	C	NADH flavin oxidoreductase NADH oxidase
MAG.T21.45_00458	760192.Halhy_4818	1.5e-225	790.4	Sphingobacteriia													Bacteria	1IYSQ@117747,4P8KP@976,COG3210@1,COG3210@2	NA|NA|NA	U	IMG reference gene
MAG.T21.45_00459	760192.Halhy_3863	5.7e-40	171.4	Bacteria													Bacteria	2CIAY@1,2ZDT2@2	NA|NA|NA		
MAG.T21.45_00460	760192.Halhy_3864	0.0	1201.4	Bacteroidetes													Bacteria	4PKBQ@976,COG1361@1,COG1361@2,COG3209@1,COG3209@2,COG4886@1,COG4886@2	NA|NA|NA	M	SPTR CHU large protein
MAG.T21.45_00461	1122176.KB903579_gene4846	2.5e-66	259.2	Bacteria													Bacteria	COG3064@1,COG3064@2	NA|NA|NA	M	translation initiation factor activity
MAG.T21.45_00462	760192.Halhy_3866	3.5e-271	941.8	Bacteria				ko:K20276	ko02024,map02024				ko00000,ko00001				Bacteria	COG3210@1,COG3210@2	NA|NA|NA	U	domain, Protein
MAG.T21.45_00463	1122176.KB903542_gene356	2.3e-115	424.1	Bacteria				ko:K20276	ko02024,map02024				ko00000,ko00001				Bacteria	COG3210@1,COG3210@2,COG3292@1,COG3292@2	NA|NA|NA	U	domain, Protein
MAG.T21.45_00464	1122176.KB903542_gene358	8.7e-18	96.7	Sphingobacteriia	yraN			ko:K07460					ko00000				Bacteria	1ITMT@117747,4NS7E@976,COG0792@1,COG0792@2	NA|NA|NA	L	Belongs to the UPF0102 family
MAG.T21.45_00465	1185876.BN8_04107	1.6e-146	526.2	Cytophagia													Bacteria	47MFM@768503,4NG5T@976,COG0673@1,COG0673@2	NA|NA|NA	S	Putative oxidoreductase C terminal domain
MAG.T21.45_00466	760192.Halhy_1679	1.2e-230	806.2	Sphingobacteriia	rnr			ko:K12573,ko:K12585	ko03018,map03018	M00391			ko00000,ko00001,ko00002,ko01000,ko03016,ko03019				Bacteria	1IPGD@117747,4NE7T@976,COG0557@1,COG0557@2	NA|NA|NA	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MAG.T21.45_00468	760192.Halhy_1677	4.2e-82	311.2	Sphingobacteriia	sdhC			ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002				Bacteria	1IQH2@117747,2CAZH@1,2Z7RU@2,4NGM5@976	NA|NA|NA	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family
MAG.T21.45_00469	760192.Halhy_1676	0.0	1079.7	Sphingobacteriia	sdhA		1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQ4F@117747,4NFDU@976,COG1053@1,COG1053@2	NA|NA|NA	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit
MAG.T21.45_00470	760192.Halhy_1675	9e-104	383.3	Sphingobacteriia	frdB		1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_2395	Bacteria	1IQMQ@117747,4NFR3@976,COG0479@1,COG0479@2	NA|NA|NA	C	Succinate dehydrogenase fumarate reductase Fe-S protein subunit
MAG.T21.45_00471	760192.Halhy_1608	1.3e-77	296.2	Sphingobacteriia													Bacteria	1ITBG@117747,4NMV7@976,COG3000@1,COG3000@2	NA|NA|NA	I	Fatty acid hydroxylase
MAG.T21.45_00472	760192.Halhy_1607	8.6e-151	540.0	Sphingobacteriia	cysK		2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQU6@117747,4NDZ9@976,COG0031@1,COG0031@2	NA|NA|NA	E	Cystathionine beta-synthase
MAG.T21.45_00473	1250005.PHEL85_2086	1.9e-70	272.7	Flavobacteriia			3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728			ko00000,ko00001,ko00002,ko01000,ko01002,ko03110				Bacteria	1HXR3@117743,4PKDQ@976,COG0265@1,COG0265@2,COG0657@1,COG0657@2	NA|NA|NA	I	PFAM alpha beta hydrolase fold
MAG.T21.45_00474	760192.Halhy_1606	6e-36	157.1	Bacteria			3.6.1.55	ko:K03574					ko00000,ko01000,ko03400				Bacteria	COG1051@1,COG1051@2	NA|NA|NA	F	GDP-mannose mannosyl hydrolase activity
MAG.T21.45_00475	760192.Halhy_4526	4.4e-185	654.4	Sphingobacteriia	lepB		3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060				ko00000,ko00001,ko01000,ko01002				Bacteria	1IRAK@117747,4NFTP@976,COG0681@1,COG0681@2	NA|NA|NA	U	Belongs to the peptidase S26 family
MAG.T21.45_00477	760192.Halhy_1727	5.3e-72	277.7	Sphingobacteriia	polB		2.7.7.7	ko:K02336,ko:K07501					ko00000,ko01000,ko03400				Bacteria	1J0WR@117747,4PKQ5@976,COG0417@1,COG0417@2	NA|NA|NA	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB
MAG.T21.45_00478	1122179.KB890480_gene3074	2.3e-27	129.8	Sphingobacteriia													Bacteria	1J0WS@117747,4NVE9@976,COG4372@1,COG4372@2	NA|NA|NA	S	Transposase
MAG.T21.45_00479	1122176.KB903587_gene4388	1e-46	193.0	Sphingobacteriia													Bacteria	1IYFT@117747,2AUDP@1,31K1P@2,4NRCQ@976	NA|NA|NA	S	Protein of unknown function (DUF2452)
MAG.T21.45_00480	319236.JCM19294_553	6.2e-20	103.6	Nonlabens	dgkA		2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231		R02240	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	1I2YQ@117743,3HKKF@363408,4NQ39@976,COG0818@1,COG0818@2	NA|NA|NA	M	Prokaryotic diacylglycerol kinase
MAG.T21.45_00481	760192.Halhy_1281	5.4e-68	266.2	Sphingobacteriia													Bacteria	1IPQ3@117747,4NHM6@976,COG4288@1,COG4288@2	NA|NA|NA	S	Lamin Tail Domain
MAG.T21.45_00482	760192.Halhy_1283	4e-128	464.5	Sphingobacteriia	asd		1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000			iLJ478.TM1523	Bacteria	1IQCT@117747,4NE4V@976,COG0136@1,COG0136@2	NA|NA|NA	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MAG.T21.45_00483	760192.Halhy_1284	4e-118	431.8	Bacteria				ko:K02557,ko:K18376	ko02030,ko02040,map02030,map02040	M00660			ko00000,ko00001,ko00002,ko02000,ko02035,ko02044	1.A.30.1,1.C.65.1			Bacteria	COG1196@1,COG1196@2	NA|NA|NA	D	nuclear chromosome segregation
MAG.T21.45_00484	760192.Halhy_3759	3.7e-111	407.9	Sphingobacteriia													Bacteria	1INP8@117747,2BZ6M@1,2Z7HW@2,4NDZE@976	NA|NA|NA	S	Domain of Unknown Function (DUF1080)
MAG.T21.45_00485	391603.FBALC1_01942	1e-98	366.7	Flavobacteriia			3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130		R00552	RC00177	ko00000,ko00001,ko01000				Bacteria	1I0NU@117743,4NGKJ@976,COG1834@1,COG1834@2	NA|NA|NA	E	Amidinotransferase
MAG.T21.45_00486	1122176.KB903532_gene2580	2.3e-131	475.7	Sphingobacteriia	adiC			ko:K03294,ko:K03759					ko00000,ko02000	2.A.3.2			Bacteria	1IP7H@117747,4NIZB@976,COG0531@1,COG0531@2	NA|NA|NA	E	PFAM Amino acid
MAG.T21.45_00487	760192.Halhy_0309	3.7e-36	158.7	Sphingobacteriia													Bacteria	1IUBQ@117747,28J3Q@1,2Z8ZW@2,4NGJW@976	NA|NA|NA	S	Protein of unknown function (Porph_ging)
MAG.T21.45_00488	761193.Runsl_2121	1.6e-214	753.1	Cytophagia													Bacteria	47JEF@768503,4NF88@976,COG1629@1,COG1629@2	NA|NA|NA	P	Outer membrane protein beta-barrel family
MAG.T21.45_00490	760192.Halhy_4802	1.3e-78	300.8	Sphingobacteriia				ko:K03286					ko00000,ko02000	1.B.6			Bacteria	1IXGD@117747,4NIV8@976,COG2885@1,COG2885@2	NA|NA|NA	M	OmpA MotB domain protein
MAG.T21.45_00491	760192.Halhy_4825	3e-160	572.0	Sphingobacteriia													Bacteria	1ITAS@117747,4NF1M@976,COG1404@1,COG1404@2	NA|NA|NA	O	Serine protease, subtilase family
MAG.T21.45_00493	760192.Halhy_4817	3.8e-27	127.1	Sphingobacteriia	rpmB	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02902	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IUBT@117747,4NS7Q@976,COG0227@1,COG0227@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL28 family
MAG.T21.45_00494	760192.Halhy_4816	6.6e-24	115.9	Sphingobacteriia	rpmG			ko:K02913	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IU0P@117747,4NURM@976,COG0267@1,COG0267@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL33 family
MAG.T21.45_00496	1122176.KB903576_gene4941	6.8e-125	453.8	Sphingobacteriia	ftsY			ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7			Bacteria	1IPD8@117747,4NE9Z@976,COG0552@1,COG0552@2	NA|NA|NA	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MAG.T21.45_00497	760192.Halhy_4812	1.2e-33	149.8	Bacteroidetes													Bacteria	2DEWU@1,2ZPJP@2,4NPJW@976	NA|NA|NA		
MAG.T21.45_00498	1121007.AUML01000001_gene1359	8.4e-42	177.9	Aquimarina													Bacteria	1HX0X@117743,2YJ4S@290174,4NFZ6@976,COG4850@1,COG4850@2	NA|NA|NA	S	Uncharacterized conserved protein (DUF2183)
MAG.T21.45_00499	1122176.KB903576_gene4929	3.2e-30	138.3	Sphingobacteriia				ko:K12976					ko00000,ko01000,ko01005				Bacteria	1IU44@117747,4NNFR@976,COG3637@1,COG3637@2	NA|NA|NA	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MAG.T21.45_00500	760192.Halhy_4809	7.5e-95	354.0	Sphingobacteriia	qor	GO:0000166,GO:0003674,GO:0003824,GO:0003960,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0010941,GO:0016491,GO:0016651,GO:0016655,GO:0019362,GO:0019637,GO:0034641,GO:0036094,GO:0042802,GO:0042803,GO:0042981,GO:0043067,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0048038,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0051186,GO:0055086,GO:0055114,GO:0065007,GO:0070402,GO:0071704,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564	1.6.5.5	ko:K00344					ko00000,ko01000				Bacteria	1IP5X@117747,4NEYW@976,COG0604@1,COG0604@2	NA|NA|NA	C	PFAM Alcohol dehydrogenase
MAG.T21.45_00501	760192.Halhy_4808	1.6e-71	275.8	Sphingobacteriia	ribA	GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000			iAPECO1_1312.APECO1_437,iPC815.YPO2222,iSbBS512_1146.SbBS512_E1505,iUTI89_1310.UTI89_C1548	Bacteria	1J0XM@117747,4PNQF@976,COG0807@1,COG0807@2	NA|NA|NA	H	GTP cyclohydrolase II
MAG.T21.45_00502	760192.Halhy_0430	2.7e-155	555.1	Sphingobacteriia	metZ	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48,4.4.1.8	ko:K01739,ko:K01760,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv0391	Bacteria	1INWU@117747,4PKE6@976,COG0626@1,COG0626@2	NA|NA|NA	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide
MAG.T21.45_00503	760192.Halhy_5550	5.9e-35	154.1	Sphingobacteriia	yhfA			ko:K07397					ko00000				Bacteria	1IT1R@117747,4NNTY@976,COG1765@1,COG1765@2	NA|NA|NA	O	redox protein regulator of disulfide bond formation
MAG.T21.45_00504	1356852.N008_05735	3.6e-201	707.6	Cytophagia	metY		2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100		R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000			iNJ661.Rv3340	Bacteria	47M8Z@768503,4NE27@976,COG2873@1,COG2873@2	NA|NA|NA	E	PFAM Cys Met metabolism PLP-dependent enzyme
MAG.T21.45_00505	760192.Halhy_5551	9.3e-118	430.3	Sphingobacteriia	metXA		2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130		R01776	RC00004,RC00041	ko00000,ko00001,ko01000				Bacteria	1IQEA@117747,4NFG2@976,COG2021@1,COG2021@2	NA|NA|NA	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MAG.T21.45_00506	925409.KI911562_gene877	3.6e-95	355.9	Sphingobacteriia			3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504				Bacteria	1INNE@117747,4NDYP@976,COG2367@1,COG2367@2	NA|NA|NA	V	Beta-lactamase enzyme family
MAG.T21.45_00507	760192.Halhy_2137	1.4e-62	247.3	Sphingobacteriia													Bacteria	1J03U@117747,4NQCQ@976,COG1572@1,COG1572@2	NA|NA|NA	S	N-acetylmuramoyl-L-alanine amidase
MAG.T21.45_00508	1094466.KQS_13280	3.1e-38	166.4	Flavobacteriia													Bacteria	1HXZF@117743,4NHEC@976,COG0526@1,COG0526@2	NA|NA|NA	CO	Thioredoxin-like
MAG.T21.45_00509	649349.Lbys_0667	3.6e-56	224.6	Cytophagia	tag		3.2.2.20	ko:K01246	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	47PXB@768503,4NGRC@976,COG2818@1,COG2818@2	NA|NA|NA	L	PFAM methyladenine glycosylase
MAG.T21.45_00510	760192.Halhy_0214	0.0	1232.2	Bacteroidetes			3.2.1.4,5.2.1.8	ko:K01179,ko:K03768,ko:K08738	ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko03110	3.D.4.6	GH5,GH9		Bacteria	4PN79@976,COG3291@1,COG3291@2,COG3386@1,COG3386@2	NA|NA|NA	G	C-terminal domain of CHU protein family
MAG.T21.45_00511	1122176.KB903531_gene2890	9.1e-272	943.0	Sphingobacteriia													Bacteria	1IW7P@117747,4NF4B@976,COG1629@1,COG4771@2	NA|NA|NA	P	TonB dependent receptor
MAG.T21.45_00513	1121094.KB894643_gene1665	6.2e-94	351.3	Bacteroidaceae													Bacteria	2FM4Q@200643,4AKDX@815,4NDZJ@976,COG0582@1,COG0582@2	NA|NA|NA	L	Belongs to the 'phage' integrase family
MAG.T21.45_00514	1121094.KB894646_gene174	1.6e-08	65.1	Bacteroidaceae													Bacteria	28ZY9@1,2G1S4@200643,313WS@2,4ASCT@815,4PIFF@976	NA|NA|NA	S	Psort location Cytoplasmic, score 8.96
MAG.T21.45_00515	290315.Clim_1284	2.5e-49	203.0	Chlorobi													Bacteria	1FF7S@1090,COG4704@1,COG4704@2	NA|NA|NA	S	Fibrobacter succinogenes major domain (Fib_succ_major)
MAG.T21.45_00516	1123278.KB893553_gene3879	2.9e-12	79.7	Cytophagia													Bacteria	47U9D@768503,4NVZX@976,COG1716@1,COG1716@2	NA|NA|NA	T	Forkhead associated domain
MAG.T21.45_00519	391598.FBBAL38_13100	7.6e-45	187.6	Flavobacteriia			3.1.3.16	ko:K20074					ko00000,ko01000,ko01009				Bacteria	1IIKW@117743,4NPJV@976,COG0631@1,COG0631@2	NA|NA|NA	T	Serine/threonine phosphatases, family 2C, catalytic domain
MAG.T21.45_00520	880071.Fleli_2950	1.5e-37	163.3	Cytophagia													Bacteria	47JVB@768503,4NKYQ@976,COG0457@1,COG0457@2,COG4249@1,COG4249@2	NA|NA|NA	S	Caspase domain
MAG.T21.45_00523	1229487.AMYW01000016_gene2473	8.7e-09	65.9	Flavobacterium	htpX			ko:K03799		M00743			ko00000,ko00002,ko01000,ko01002				Bacteria	1IAN8@117743,2NWE3@237,4NWE3@976,COG0501@1,COG0501@2	NA|NA|NA	O	Belongs to the peptidase M48B family
MAG.T21.45_00525	391598.FBBAL38_13120	9.3e-18	96.7	Bacteroidetes													Bacteria	2DPKG@1,332IB@2,4P8M9@976	NA|NA|NA	S	Protein of unknown function (DUF3293)
MAG.T21.45_00527	572477.Alvin_2300	3e-38	165.6	Proteobacteria													Bacteria	1ND0K@1224,2EEJB@1,338DB@2	NA|NA|NA		
MAG.T21.45_00528	471854.Dfer_1719	2e-41	174.9	Cytophagia													Bacteria	47VXZ@768503,4NR5F@976,COG1396@1,COG1396@2	NA|NA|NA	K	Helix-turn-helix domain
MAG.T21.45_00529	421072.IO89_11845	2.1e-34	151.4	Chryseobacterium		GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0045926,GO:0045927,GO:0046483,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0065007,GO:0070482,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360											Bacteria	1I45W@117743,3HIY3@358033,4NSFF@976,COG4679@1,COG4679@2	NA|NA|NA	S	Phage derived protein Gp49-like (DUF891)
MAG.T21.45_00530	1279009.ADICEAN_01002	1.3e-73	283.9	Cytophagia				ko:K14645	ko02024,map02024				ko00000,ko00001,ko01000,ko01002,ko03110				Bacteria	47MBD@768503,4NI53@976,COG1404@1,COG1404@2	NA|NA|NA	O	Peptidase S8
MAG.T21.45_00531	700598.Niako_6609	1.3e-76	293.9	Sphingobacteriia				ko:K03299					ko00000,ko02000	2.A.8			Bacteria	1IQKX@117747,4NFQH@976,COG2610@1,COG2610@2	NA|NA|NA	EG	COGs COG2610 H gluconate symporter and related permease
MAG.T21.45_00532	471854.Dfer_1448	1.8e-37	162.2	Cytophagia													Bacteria	47QEP@768503,4NQ4A@976,COG3832@1,COG3832@2	NA|NA|NA	S	Activator of Hsp90 ATPase homolog 1-like protein
MAG.T21.45_00533	1089547.KB913013_gene4725	3.3e-101	374.8	Cytophagia													Bacteria	47KYG@768503,4NH6R@976,COG1028@1,COG1028@2	NA|NA|NA	IQ	Enoyl-(Acyl carrier protein) reductase
MAG.T21.45_00534	714943.Mucpa_3674	2e-102	379.0	Sphingobacteriia													Bacteria	1IPCE@117747,4NFMZ@976,COG0179@1,COG0179@2	NA|NA|NA	Q	PFAM Fumarylacetoacetate (FAA) hydrolase family
MAG.T21.45_00535	925409.KI911562_gene37	5e-94	350.9	Sphingobacteriia													Bacteria	1IQBS@117747,4NH6Y@976,COG1028@1,COG1028@2	NA|NA|NA	IQ	short-chain dehydrogenase
MAG.T21.45_00536	929562.Emtol_1774	1.4e-186	659.4	Cytophagia	uxaA		3.1.1.17,4.2.1.42,4.2.1.7	ko:K01053,ko:K01685,ko:K01708	ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129,M00631	R01519,R01540,R02933,R03751,R05608	RC00537,RC00543,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	47K7S@768503,4NFVQ@976,COG2721@1,COG2721@2	NA|NA|NA	G	PFAM D-galactarate dehydratase Altronate hydrolase
MAG.T21.45_00537	929562.Emtol_2587	1.4e-154	552.7	Cytophagia				ko:K02429					ko00000,ko02000	2.A.1.7			Bacteria	47JBN@768503,4NEYR@976,COG0738@1,COG0738@2	NA|NA|NA	G	PFAM Major Facilitator Superfamily
MAG.T21.45_00538	929562.Emtol_3843	3.5e-57	228.4	Cytophagia	yfkO												Bacteria	47Q2S@768503,4NEA5@976,COG0778@1,COG0778@2	NA|NA|NA	C	Nitroreductase family
MAG.T21.45_00539	1122176.KB903531_gene3153	3e-61	242.3	Bacteroidetes	gluQ		6.1.1.17	ko:K01885,ko:K01894	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016				Bacteria	4NP0Y@976,COG0008@1,COG0008@2	NA|NA|NA	J	Belongs to the class-I aminoacyl-tRNA synthetase family
MAG.T21.45_00540	755732.Fluta_2390	2.2e-72	278.9	Bacteroidetes			1.14.18.2	ko:K08080,ko:K14952	ko00520,ko05152,map00520,map05152		R01115,R01803	RC00157	ko00000,ko00001,ko01000				Bacteria	4P433@976,COG2220@1,COG2220@2	NA|NA|NA	S	Beta-lactamase superfamily domain
MAG.T21.45_00541	760192.Halhy_1492	0.0	1240.7	Sphingobacteriia													Bacteria	1INVS@117747,4NE13@976,COG0308@1,COG0308@2	NA|NA|NA	E	COG0308 Aminopeptidase N
MAG.T21.45_00542	760192.Halhy_5692	1e-253	882.5	Sphingobacteriia	pyrG	GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iNJ661.Rv1699,iPC815.YPO3377	Bacteria	1IP4J@117747,4NEWT@976,COG0504@1,COG0504@2	NA|NA|NA	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MAG.T21.45_00543	768671.ThimaDRAFT_4338	6e-73	281.2	Chromatiales				ko:K08974					ko00000				Bacteria	1MXVI@1224,1RN4B@1236,1WYST@135613,COG2035@1,COG2035@2	NA|NA|NA	S	Domain of unknown function (DUF368)
MAG.T21.45_00544	203275.BFO_2948	1.1e-64	253.4	Porphyromonadaceae	aroE		1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000				Bacteria	22WMN@171551,2FP6C@200643,4NEBJ@976,COG0169@1,COG0169@2	NA|NA|NA	E	Shikimate
MAG.T21.45_00545	760192.Halhy_6381	4.3e-111	408.3	Sphingobacteriia	putA			ko:K00318,ko:K18318	ko00330,ko00332,ko01100,ko01110,ko01130,ko02024,map00330,map00332,map01100,map01110,map01130,map02024		R10507	RC00083	ko00000,ko00001,ko01000				Bacteria	1IQ4H@117747,4NEH5@976,COG0506@1,COG0506@2	NA|NA|NA	E	Proline dehydrogenase
MAG.T21.45_00546	1131812.JQMS01000001_gene1692	1.4e-101	375.9	Flavobacterium				ko:K06911					ko00000				Bacteria	1HYY2@117743,2NSN5@237,4NGJ5@976,COG1741@1,COG1741@2	NA|NA|NA	S	Belongs to the pirin family
MAG.T21.45_00547	760192.Halhy_6383	8.9e-89	334.0	Sphingobacteriia													Bacteria	1IPV1@117747,28JI8@1,2Z9BM@2,4NE5E@976	NA|NA|NA	S	S1 P1 Nuclease
MAG.T21.45_00548	313603.FB2170_04530	6.1e-114	417.5	Maribacter	yocS			ko:K03453					ko00000	2.A.28			Bacteria	1HY0F@117743,2PGR5@252356,4NEIM@976,COG0385@1,COG0385@2	NA|NA|NA	S	Sodium Bile acid symporter family
MAG.T21.45_00549	313603.FB2170_04510	1.4e-55	222.6	Maribacter													Bacteria	1I1J9@117743,2PHH9@252356,4NPF9@976,COG0251@1,COG0251@2	NA|NA|NA	J	YjgF/chorismate_mutase-like, putative endoribonuclease
MAG.T21.45_00550	1168034.FH5T_13870	1.4e-146	526.2	Bacteroidia	ce		5.1.3.11,5.1.3.8	ko:K01787,ko:K16213	ko00520,map00520		R01207,R01445,R10810	RC00289,RC00290	ko00000,ko00001,ko01000				Bacteria	2FN6V@200643,4NEFV@976,COG2942@1,COG2942@2	NA|NA|NA	G	N-acylglucosamine 2-epimerase
MAG.T21.45_00552	1034807.FBFL15_0377	1.7e-114	419.1	Flavobacteriia													Bacteria	1IBPT@117743,4NGSI@976,COG5464@1,COG5464@2	NA|NA|NA	S	to proteins from other organisms
MAG.T21.45_00554	395493.BegalDRAFT_1033	5.8e-09	68.2	Gammaproteobacteria													Bacteria	1NIS7@1224,1SQ6P@1236,COG1403@1,COG1403@2	NA|NA|NA	V	HNH endonuclease
MAG.T21.45_00555	525898.Sdel_0032	1.4e-38	167.5	Epsilonproteobacteria													Bacteria	1MUE0@1224,2YSHR@29547,430UI@68525,COG3950@1,COG3950@2	NA|NA|NA	S	AAA ATPase domain
MAG.T21.45_00557	1341181.FLJC2902T_32370	5e-88	330.5	Flavobacterium	fic	GO:0008150,GO:0050789,GO:0050794,GO:0051302,GO:0065007		ko:K04095					ko00000,ko03036				Bacteria	1I12I@117743,2NYNF@237,4NID4@976,COG2184@1,COG2184@2	NA|NA|NA	D	Fic/DOC family
MAG.T21.45_00558	1121904.ARBP01000001_gene5348	3.8e-41	175.3	Cytophagia	wcoO												Bacteria	47YFF@768503,4PN0T@976,COG1030@1,COG1030@2	NA|NA|NA		
MAG.T21.45_00559	760192.Halhy_0749	3.3e-268	930.6	Sphingobacteriia	ybiT	GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896		ko:K06158					ko00000,ko03012				Bacteria	1IP6T@117747,4NEHU@976,COG0488@1,COG0488@2	NA|NA|NA	S	COGs COG0488 ATPase components of ABC transporter with duplicated ATPase domains
MAG.T21.45_00560	1123248.KB893337_gene2450	1.9e-116	426.0	Sphingobacteriia													Bacteria	1IVQN@117747,4NFGY@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_00561	616991.JPOO01000001_gene4180	9.4e-188	662.9	Arenibacter				ko:K02429,ko:K06610,ko:K08369					ko00000,ko02000	2.A.1,2.A.1.1.27,2.A.1.7			Bacteria	1HYBZ@117743,23G7B@178469,4NFTC@976,COG0738@1,COG0738@2	NA|NA|NA	G	Major Facilitator Superfamily
MAG.T21.45_00562	760192.Halhy_5025	2.6e-134	485.3	Sphingobacteriia			3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1IR1I@117747,4NGPG@976,COG2865@1,COG2865@2	NA|NA|NA	K	Putative DNA-binding domain
MAG.T21.45_00563	755732.Fluta_3728	0.0	1434.9	Flavobacteriia	copA2												Bacteria	1HWXY@117743,4NE3N@976,COG2132@1,COG2132@2	NA|NA|NA	Q	Multicopper oxidase
MAG.T21.45_00564	755732.Fluta_3729	1.3e-130	472.6	Cryomorphaceae	mtrC			ko:K02005,ko:K13888		M00709			ko00000,ko00002,ko02000	8.A.1			Bacteria	1HYRA@117743,2PC24@246874,4NG8S@976,COG0845@1,COG0845@2,COG2608@1,COG2608@2	NA|NA|NA	M	Protein of unknown function (DUF3347)
MAG.T21.45_00565	755732.Fluta_3730	6.3e-29	132.9	Cryomorphaceae	merP			ko:K07213,ko:K08364	ko04978,map04978				ko00000,ko00001,ko02000	1.A.72.1			Bacteria	1IC9G@117743,2PC2S@246874,4P9HN@976,COG2608@1,COG2608@2	NA|NA|NA	C	mercury ion transmembrane transporter activity
MAG.T21.45_00566	755732.Fluta_3731	0.0	1405.2	Cryomorphaceae	copA		3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016		R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5			Bacteria	1HWUI@117743,2PAFY@246874,4NERS@976,COG2217@1,COG2217@2	NA|NA|NA	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC
MAG.T21.45_00567	755732.Fluta_3732	2.6e-68	265.0	Cryomorphaceae													Bacteria	1IG6G@117743,2PBPB@246874,4PJ0D@976,COG2207@1,COG2207@2	NA|NA|NA	K	PFAM Bacterial regulatory helix-turn-helix proteins, AraC family
MAG.T21.45_00568	1048983.EL17_15655	2.9e-43	181.8	Cytophagia				ko:K15977					ko00000				Bacteria	47TKZ@768503,4NJS6@976,COG5421@1,COG5421@2	NA|NA|NA	L	Transposase IS4 family
MAG.T21.45_00569	1189619.pgond44_14618	4.9e-32	143.7	Psychroflexus													Bacteria	1I32Z@117743,4C4DC@83612,4NR5F@976,COG1396@1,COG1396@2	NA|NA|NA	K	Helix-turn-helix domain
MAG.T21.45_00570	1341181.FLJC2902T_30790	5.5e-14	83.2	Flavobacterium		GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0045926,GO:0045927,GO:0046483,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0065007,GO:0070482,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360											Bacteria	1IIBX@117743,2P0CC@237,4NTZW@976,COG4679@1,COG4679@2	NA|NA|NA	S	Phage derived protein Gp49-like (DUF891)
MAG.T21.45_00572	216432.CA2559_08401	2.7e-16	91.7	Flavobacteriia													Bacteria	1I2SE@117743,2AI4E@1,318IH@2,4NQNN@976	NA|NA|NA		
MAG.T21.45_00575	1121904.ARBP01000009_gene4389	9.5e-157	560.1	Cytophagia													Bacteria	47JAV@768503,4NF9W@976,COG0671@1,COG0671@2	NA|NA|NA	I	PAP2 superfamily
MAG.T21.45_00576	388413.ALPR1_19718	5.4e-294	1017.3	Cytophagia													Bacteria	47MGE@768503,4NEE8@976,COG4888@1,COG4888@2	NA|NA|NA	S	ASPIC and UnbV
MAG.T21.45_00577	760192.Halhy_1519	0.0	1330.1	Sphingobacteriia													Bacteria	1IVZC@117747,4NEE8@976,COG4888@1,COG4888@2	NA|NA|NA	S	ASPIC and UnbV
MAG.T21.45_00578	1123248.KB893362_gene4498	3e-35	155.2	Sphingobacteriia													Bacteria	1IYY8@117747,2BTVE@1,32P38@2,4NRR1@976	NA|NA|NA		
MAG.T21.45_00579	760192.Halhy_1519	0.0	1184.9	Sphingobacteriia													Bacteria	1IVZC@117747,4NEE8@976,COG4888@1,COG4888@2	NA|NA|NA	S	ASPIC and UnbV
MAG.T21.45_00580	388413.ALPR1_19728	2.2e-197	695.3	Bacteroidetes				ko:K21572					ko00000,ko02000	8.A.46.1,8.A.46.3			Bacteria	4PMMP@976,COG0561@1,COG0561@2	NA|NA|NA	S	Pfam:SusD
MAG.T21.45_00581	388413.ALPR1_19733	0.0	1213.0	Cytophagia													Bacteria	47Y44@768503,4P258@976,COG4206@1,COG4206@2	NA|NA|NA	P	PFAM TonB-dependent Receptor Plug
MAG.T21.45_00582	760192.Halhy_2528	1.1e-38	166.4	Sphingobacteriia	ybeY	GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.6.99.2,3.5.4.5	ko:K01489,ko:K03474,ko:K03595,ko:K07042	ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100	M00124	R01878,R02485,R05838,R08221	RC00074,RC00514,RC01476	ko00000,ko00001,ko00002,ko01000,ko03009,ko03029				Bacteria	1ISZQ@117747,4NS93@976,COG0319@1,COG0319@2	NA|NA|NA	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MAG.T21.45_00583	1122176.KB903550_gene4280	6.3e-37	160.2	Sphingobacteriia	rsbW		2.7.11.1	ko:K04757,ko:K08282					ko00000,ko01000,ko01001,ko03021				Bacteria	1IT0C@117747,4NRAA@976,COG2172@1,COG2172@2	NA|NA|NA	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MAG.T21.45_00584	760192.Halhy_3997	1.2e-200	707.2	Sphingobacteriia	tccA2		2.1.1.80,3.1.1.61,3.1.21.4	ko:K01155,ko:K07011,ko:K13924	ko02020,ko02030,map02020,map02030	M00506			ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko02048				Bacteria	1J0XD@117747,4NF7P@976,COG1196@1,COG1196@2,COG3206@1,COG3206@2	NA|NA|NA	D	protein involved in exopolysaccharide biosynthesis
MAG.T21.45_00585	1122176.KB903555_gene3744	5.4e-204	718.0	Sphingobacteriia	pepN		3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100		R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002				Bacteria	1INM2@117747,4NFTN@976,COG0308@1,COG0308@2,COG1413@1,COG1413@2	NA|NA|NA	CE	PFAM Peptidase M1 membrane alanine aminopeptidase
MAG.T21.45_00586	1122176.KB903555_gene3743	6e-87	327.4	Sphingobacteriia	ohpC		3.7.1.14	ko:K05714	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R02603,R06789	RC00752,RC00753,RC01337	br01602,ko00000,ko00001,ko00002,ko01000				Bacteria	1INU7@117747,4NF80@976,COG2267@1,COG2267@2	NA|NA|NA	I	Alpha beta hydrolase
MAG.T21.45_00587	760192.Halhy_2842	5.1e-62	244.6	Bacteroidetes				ko:K02557	ko02030,ko02040,map02030,map02040				ko00000,ko00001,ko02000,ko02035	1.A.30.1			Bacteria	4NGHP@976,COG1360@1,COG1360@2	NA|NA|NA	N	Ompa motb domain protein
MAG.T21.45_00588	760192.Halhy_2598	4.9e-29	134.0	Sphingobacteriia	apaG			ko:K06195					ko00000				Bacteria	1ISSC@117747,4NNRA@976,COG2967@1,COG2967@2	NA|NA|NA	P	protein affecting Mg2 Co2 transport
MAG.T21.45_00589	760192.Halhy_2597	5.4e-46	191.0	Sphingobacteriia	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8,4.1.1.23	ko:K00942,ko:K01591	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00050,M00051	R00332,R00965,R02090	RC00002,RC00409	ko00000,ko00001,ko00002,ko01000			iAPECO1_1312.APECO1_2813,iIT341.HP0321,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193	Bacteria	1IRC3@117747,4NEDG@976,COG0194@1,COG0194@2	NA|NA|NA	F	Essential for recycling GMP and indirectly, cGMP
MAG.T21.45_00590	760192.Halhy_2596	3.1e-76	292.0	Sphingobacteriia	yicC			ko:K03316					ko00000	2.A.36			Bacteria	1IQ8K@117747,4NEU4@976,COG1561@1,COG1561@2	NA|NA|NA	S	PFAM YicC-like family, N-terminal region
MAG.T21.45_00591	760192.Halhy_2595	2.9e-40	171.0	Sphingobacteriia	hupA			ko:K03530					ko00000,ko03032,ko03036,ko03400				Bacteria	1ISXQ@117747,4NT0D@976,COG0776@1,COG0776@2	NA|NA|NA	L	Belongs to the bacterial histone-like protein family
MAG.T21.45_00592	760192.Halhy_2594	2.8e-55	222.2	Sphingobacteriia													Bacteria	1J0X1@117747,4PP1I@976,COG4783@1,COG4783@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.45_00593	760192.Halhy_2593	2e-211	741.9	Sphingobacteriia	rng		3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394			ko00000,ko00001,ko00002,ko01000,ko03009,ko03019				Bacteria	1IQ78@117747,4NED1@976,COG1530@1,COG1530@2	NA|NA|NA	J	ribonuclease, Rne Rng family
MAG.T21.45_00594	1123248.KB893386_gene1879	1.2e-62	247.3	Sphingobacteriia													Bacteria	1IX57@117747,4NFRJ@976,COG0707@1,COG0707@2	NA|NA|NA	M	Glycosyl transferase family 1
MAG.T21.45_00595	1121889.AUDM01000002_gene468	5.9e-60	237.3	Flavobacterium	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056					ko00000,ko01000,ko03012				Bacteria	1HX7R@117743,2NT2U@237,4NI7N@976,COG0193@1,COG0193@2	NA|NA|NA	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MAG.T21.45_00596	1122179.KB890419_gene26	4e-126	457.6	Sphingobacteriia	dapD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.117,2.3.1.89	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	M00016,M00525	R04364,R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000			iSbBS512_1146.SbBS512_E0158,iYO844.BSU14180	Bacteria	1INN5@117747,4NEWD@976,COG2171@1,COG2171@2	NA|NA|NA	E	Belongs to the transferase hexapeptide repeat family
MAG.T21.45_00597	760192.Halhy_2776	2.4e-121	442.6	Sphingobacteriia													Bacteria	1IZE7@117747,2BV6Z@1,32QKE@2,4PCAH@976	NA|NA|NA		
MAG.T21.45_00598	761193.Runsl_1070	0.0	1332.4	Cytophagia				ko:K08676					ko00000,ko01000,ko01002				Bacteria	47NFD@768503,4NGU2@976,COG0793@1,COG0793@2,COG4946@1,COG4946@2	NA|NA|NA	M	Tricorn protease homolog
MAG.T21.45_00599	1279009.ADICEAN_01375	6.4e-111	407.5	Cytophagia													Bacteria	2CEJ5@1,2Z7RK@2,47N0C@768503,4NGWQ@976	NA|NA|NA		
MAG.T21.45_00600	865937.Gilli_3112	2.6e-47	196.4	Flavobacteriia			2.7.13.3	ko:K02484					ko00000,ko01000,ko01001,ko02022				Bacteria	1HZPN@117743,4PKBV@976,COG5002@1,COG5002@2	NA|NA|NA	T	Histidine kinase
MAG.T21.45_00601	1348583.ATLH01000028_gene102	2.4e-55	222.2	Cellulophaga													Bacteria	1F9GM@104264,1I1ST@117743,4NMAC@976,COG0745@1,COG0745@2	NA|NA|NA	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MAG.T21.45_00602	313606.M23134_02285	4e-24	117.9	Cytophagia													Bacteria	2DNUQ@1,32Z94@2,47QAG@768503,4NVH0@976	NA|NA|NA	S	Domain of unknown function (DUF4281)
MAG.T21.45_00603	509635.N824_05185	9.7e-26	124.0	Sphingobacteriia													Bacteria	1IWW9@117747,2DBAY@1,2Z84S@2,4NGXD@976	NA|NA|NA		
MAG.T21.45_00604	1122226.AUHX01000006_gene2165	8.3e-49	199.9	Flavobacteriia	XK27_02315												Bacteria	1I1Y8@117743,4NNPA@976,COG5646@1,COG5646@2	NA|NA|NA	S	Domain of unknown function (DU1801)
MAG.T21.45_00605	153721.MYP_3095	3e-53	215.3	Cytophagia	msrA		1.8.4.11	ko:K07304					ko00000,ko01000				Bacteria	47PB4@768503,4NMAJ@976,COG0225@1,COG0225@2	NA|NA|NA	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MAG.T21.45_00606	1122179.KB890425_gene3493	3.5e-178	631.3	Sphingobacteriia	nagA												Bacteria	1IPU8@117747,4NF3G@976,COG0673@1,COG0673@2	NA|NA|NA	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_00607	595460.RRSWK_05050	7e-96	358.2	Bacteria													Bacteria	COG1409@1,COG1409@2	NA|NA|NA	S	acid phosphatase activity
MAG.T21.45_00608	1239962.C943_00559	5.7e-224	783.5	Cytophagia	suc1			ko:K16211					ko00000,ko02000	2.A.2.6			Bacteria	47KS1@768503,4NE3F@976,COG2211@1,COG2211@2	NA|NA|NA	G	Major Facilitator
MAG.T21.45_00609	1313421.JHBV01000014_gene3803	6.6e-75	287.0	Bacteroidetes			3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240		R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000				Bacteria	4NGWU@976,COG1611@1,COG1611@2	NA|NA|NA	S	Belongs to the LOG family
MAG.T21.45_00610	761193.Runsl_4379	1e-206	726.9	Cytophagia													Bacteria	47MFX@768503,4NK95@976,COG4206@1,COG4206@2	NA|NA|NA	H	Outer membrane protein beta-barrel family
MAG.T21.45_00611	746697.Aeqsu_0640	9.3e-20	103.2	Flavobacteriia	glpE												Bacteria	1I51Q@117743,4NUPH@976,COG0607@1,COG0607@2	NA|NA|NA	P	rhodanese-related sulfurtransferase
MAG.T21.45_00612	760192.Halhy_2489	1e-196	693.0	Sphingobacteriia	crtI		1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37	ko:K10027,ko:K20611	ko00906,ko01100,ko01110,map00906,map01100,map01110		R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000				Bacteria	1IQI6@117747,4NF7K@976,COG1233@1,COG1233@2	NA|NA|NA	Q	COG1233 Phytoene dehydrogenase and related
MAG.T21.45_00613	760192.Halhy_2488	1.1e-113	416.4	Sphingobacteriia	crtB	GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576	2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99	ko:K00801,ko:K02291,ko:K10208	ko00100,ko00906,ko00909,ko01062,ko01100,ko01110,ko01130,map00100,map00906,map00909,map01062,map01100,map01110,map01130	M00097	R00702,R02065,R02872,R04218,R06223,R07270,R07652,R09793,R10177	RC00362,RC00796,RC01101,RC02839,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006				Bacteria	1IP80@117747,4NEIK@976,COG1562@1,COG1562@2	NA|NA|NA	I	Squalene phytoene synthase
MAG.T21.45_00614	1122179.KB890472_gene421	2.1e-40	172.6	Bacteria	cruF		5.5.1.19	ko:K22502	ko00906,map00906		R03824,R05341	RC01004	ko00000,ko00001,ko01000				Bacteria	COG2324@1,COG2324@2	NA|NA|NA	S	Carotenoid biosynthesis protein
MAG.T21.45_00615	1122176.KB903548_gene1132	1e-82	313.9	Sphingobacteriia	crtL		5.5.1.19	ko:K06443	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R03824,R04801,R05341,R06962,R07856	RC01004,RC01964	ko00000,ko00001,ko00002,ko01000				Bacteria	1IS7H@117747,4PM7G@976,COG0654@1,COG0654@2	NA|NA|NA	CH	Lycopene cyclase protein
MAG.T21.45_00616	649349.Lbys_0134	2.2e-11	74.3	Cytophagia													Bacteria	2DMVH@1,32TYD@2,47VWI@768503,4P54C@976	NA|NA|NA		
MAG.T21.45_00617	1267211.KI669560_gene439	4.2e-37	161.0	Bacteroidetes													Bacteria	28URG@1,2ZGVS@2,4P8T6@976	NA|NA|NA		
MAG.T21.45_00618	1267211.KI669560_gene438	2.8e-30	138.3	Bacteria													Bacteria	2DT0J@1,33I67@2	NA|NA|NA		
MAG.T21.45_00619	1267211.KI669560_gene437	5.5e-65	253.8	Bacteroidetes													Bacteria	2EVQR@1,33P4R@2,4NXG3@976	NA|NA|NA		
MAG.T21.45_00622	1358423.N180_01360	2.6e-165	588.6	Sphingobacteriia				ko:K06926					ko00000				Bacteria	1IRPC@117747,4NE5J@976,COG1106@1,COG1106@2	NA|NA|NA	S	AAA domain, putative AbiEii toxin, Type IV TA system
MAG.T21.45_00623	1358423.N180_01365	1.5e-45	189.1	Bacteroidetes													Bacteria	2ENPI@1,33GAX@2,4NXUJ@976	NA|NA|NA		
MAG.T21.45_00624	1121912.AUHD01000008_gene37	3.8e-30	138.3	Flavobacteriia													Bacteria	1IAQ9@117743,2EJ0S@1,33CRY@2,4NXHH@976	NA|NA|NA	S	Domain of unknown function (DUF4411)
MAG.T21.45_00625	1288963.ADIS_2283	5.8e-96	357.8	Bacteroidetes													Bacteria	4NMYC@976,COG2856@1,COG2856@2	NA|NA|NA	E	Zn peptidase
MAG.T21.45_00627	945713.IALB_0068	0.0	1096.3	Bacteria	comF		3.6.4.12	ko:K03654	ko03018,map03018				ko00000,ko00001,ko01000,ko03400				Bacteria	COG0514@1,COG0514@2,COG1040@1,COG1040@2	NA|NA|NA	K	competence protein
MAG.T21.45_00629	760192.Halhy_2417	2.9e-33	147.5	Sphingobacteriia	rpmE2	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02909	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1ITGS@117747,4NS7P@976,COG0254@1,COG0254@2	NA|NA|NA	J	Ribosomal protein L31
MAG.T21.45_00630	760192.Halhy_2418	1.8e-101	376.3	Sphingobacteriia	glmU		2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	1IP3D@117747,4NDZP@976,COG1207@1,COG1207@2	NA|NA|NA	M	Sugar nucleotidyl transferase
MAG.T21.45_00631	760192.Halhy_2419	1.3e-37	163.3	Bacteroidetes	speE		2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000				Bacteria	4NPK5@976,COG0421@1,COG0421@2	NA|NA|NA	E	Spermidine synthase
MAG.T21.45_00632	1270196.JCKI01000010_gene773	4.2e-55	221.5	Sphingobacteriia													Bacteria	1J12K@117747,4PMFJ@976,COG4221@1,COG4221@2	NA|NA|NA	S	KR domain
MAG.T21.45_00633	1124780.ANNU01000003_gene1418	2.3e-37	162.5	Cytophagia			1.1.1.325	ko:K17745	ko00790,map00790	M00843	R09989,R09990	RC00823,RC02162	ko00000,ko00001,ko00002,ko01000				Bacteria	47M5I@768503,4NG8J@976,COG4221@1,COG4221@2	NA|NA|NA	S	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAG.T21.45_00634	760192.Halhy_2400	1.4e-96	359.4	Sphingobacteriia	mlaE			ko:K02066	ko02010,map02010	M00210,M00669,M00670			ko00000,ko00001,ko00002,ko02000	3.A.1.27			Bacteria	1IQDU@117747,4NEZ8@976,COG0767@1,COG0767@2	NA|NA|NA	Q	ABC-type transport system involved in resistance to organic solvents permease component
MAG.T21.45_00635	760192.Halhy_2399	1.5e-101	375.9	Sphingobacteriia	mkl			ko:K02065	ko02010,map02010	M00210,M00669,M00670			ko00000,ko00001,ko00002,ko02000	3.A.1.27			Bacteria	1IP0Y@117747,4NETG@976,COG1127@1,COG1127@2	NA|NA|NA	Q	ABC transporter
MAG.T21.45_00637	1123277.KB893184_gene4193	2.9e-44	185.3	Cytophagia	tehB												Bacteria	47YRJ@768503,4PM23@976,COG0500@1,COG0500@2	NA|NA|NA	Q	Tellurite resistance protein TehB
MAG.T21.45_00638	1122176.KB903532_gene2687	3.2e-41	174.5	Bacteria	MA20_19755												Bacteria	COG5349@1,COG5349@2	NA|NA|NA	S	Protein of unknown function (DUF983)
MAG.T21.45_00639	760192.Halhy_2396	9.8e-75	286.6	Sphingobacteriia	fnr			ko:K01420,ko:K10716					ko00000,ko02000,ko03000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6			Bacteria	1ISBB@117747,4NFIS@976,COG0664@1,COG0664@2	NA|NA|NA	K	Crp-like helix-turn-helix domain
MAG.T21.45_00640	760192.Halhy_2844	5e-139	501.9	Sphingobacteriia													Bacteria	1J0CW@117747,2DBFN@1,2Z8ZF@2,4NGEI@976	NA|NA|NA		
MAG.T21.45_00641	760192.Halhy_3506	4.7e-283	980.3	Sphingobacteriia	mutB		5.4.99.13,5.4.99.2	ko:K01847,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000				Bacteria	1J0XB@117747,4NFS0@976,COG1884@1,COG1884@2,COG2185@1,COG2185@2	NA|NA|NA	I	methylmalonyl-CoA mutase N-terminal domain
MAG.T21.45_00642	760192.Halhy_0201	1.2e-103	382.9	Bacteroidetes			3.2.1.51	ko:K01206	ko00511,map00511				ko00000,ko00001,ko01000,ko04147		GH29		Bacteria	4NK4E@976,COG2133@1,COG2133@2	NA|NA|NA	G	Domain of Unknown Function (DUF1080)
MAG.T21.45_00644	760192.Halhy_3526	1.9e-122	446.4	Sphingobacteriia													Bacteria	1IQA3@117747,2DBCF@1,2Z8DB@2,4NG6B@976	NA|NA|NA		
MAG.T21.45_00645	760192.Halhy_3527	4e-250	870.5	Sphingobacteriia	glgP2		2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931		R02111		ko00000,ko00001,ko01000		GT35		Bacteria	1IPKK@117747,4NGR1@976,COG0058@1,COG0058@2	NA|NA|NA	G	COGs COG0058 Glucan phosphorylase
MAG.T21.45_00646	1267211.KI669560_gene617	2.8e-28	131.3	Bacteria													Bacteria	COG1733@1,COG1733@2	NA|NA|NA	K	regulation of RNA biosynthetic process
MAG.T21.45_00647	1168034.FH5T_18105	4.5e-87	327.8	Bacteroidetes				ko:K09190					ko00000				Bacteria	4NHNG@976,COG3403@1,COG3403@2	NA|NA|NA	S	YqcI/YcgG family
MAG.T21.45_00648	1288963.ADIS_1099	1.5e-48	199.9	Bacteroidetes													Bacteria	4NMJU@976,COG2207@1,COG2207@2	NA|NA|NA	K	Helix-turn-helix domain
MAG.T21.45_00649	938709.AUSH02000017_gene1068	9.7e-36	155.6	Bacteroidetes													Bacteria	2EU22@1,33MJ4@2,4NZM7@976	NA|NA|NA		
MAG.T21.45_00651	1288963.ADIS_1330	1.9e-213	748.8	Bacteroidetes			3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	4NJ6Y@976,COG2865@1,COG2865@2	NA|NA|NA	K	Divergent AAA domain
MAG.T21.45_00652	1048983.EL17_01000	2.7e-44	185.3	Cytophagia													Bacteria	47PS8@768503,4NGQJ@976,COG0664@1,COG0664@2	NA|NA|NA	T	Cyclic nucleotide-binding domain
MAG.T21.45_00653	1296416.JACB01000001_gene3111	2.4e-49	203.0	Aquimarina													Bacteria	1I0UC@117743,2YGS3@290174,4NIPY@976,COG3503@1,COG3503@2	NA|NA|NA	S	Protein of unknown function (DUF1624)
MAG.T21.45_00655	1239962.C943_00426	1.6e-08	65.9	Bacteria				ko:K15546					ko00000,ko03000				Bacteria	COG1680@1,COG1680@2,COG1813@1,COG1813@2	NA|NA|NA	K	peptidyl-tyrosine sulfation
MAG.T21.45_00658	1121904.ARBP01000006_gene3793	7e-20	104.8	Cytophagia	yyaK			ko:K07052					ko00000				Bacteria	47R9S@768503,4NFKV@976,COG1266@1,COG1266@2	NA|NA|NA	S	CAAX protease self-immunity
MAG.T21.45_00659	1122176.KB903538_gene1486	5.3e-48	198.4	Sphingobacteriia													Bacteria	1ISFF@117747,4NH1Q@976,COG2972@1,COG2972@2	NA|NA|NA	T	Histidine kinase
MAG.T21.45_00660	313606.M23134_01162	1.8e-53	216.1	Cytophagia													Bacteria	47PX6@768503,4NFZT@976,COG3279@1,COG3279@2	NA|NA|NA	K	LytTr DNA-binding domain
MAG.T21.45_00661	1122176.KB903548_gene1163	6.9e-225	786.9	Sphingobacteriia			2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100		R01804,R04435	RC00159	ko00000,ko00001,ko01000				Bacteria	1IV0R@117747,4NGW0@976,COG0517@1,COG0517@2	NA|NA|NA	S	Domain in cystathionine beta-synthase and other proteins.
MAG.T21.45_00663	886379.AEWI01000062_gene2304	2.6e-108	399.1	Marinilabiliaceae	queA		2.4.99.17	ko:K07568					ko00000,ko01000,ko03016				Bacteria	2FNJD@200643,3XIQV@558415,4NDZ5@976,COG0809@1,COG0809@2	NA|NA|NA	J	Queuosine biosynthesis protein
MAG.T21.45_00664	929713.NIASO_12280	2.2e-35	155.6	Sphingobacteriia	rpoE			ko:K03088					ko00000,ko03021				Bacteria	1IQKN@117747,4NMC0@976,COG1595@1,COG1595@2	NA|NA|NA	K	Belongs to the sigma-70 factor family. ECF subfamily
MAG.T21.45_00666	760192.Halhy_3348	1.4e-22	112.8	Sphingobacteriia													Bacteria	1IUKR@117747,2DPE1@1,331PZ@2,4NV5C@976	NA|NA|NA		
MAG.T21.45_00667	760192.Halhy_3347	1.8e-33	150.6	Sphingobacteriia													Bacteria	1IPQK@117747,4NG1I@976,COG0457@1,COG0457@2	NA|NA|NA	S	PFAM Tetratricopeptide repeat
MAG.T21.45_00668	760192.Halhy_2148	2.9e-70	271.9	Sphingobacteriia	ppgK		2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1IRJC@117747,4NFNR@976,COG1940@1,COG1940@2	NA|NA|NA	GK	ROK family
MAG.T21.45_00669	760192.Halhy_2149	1.1e-81	310.1	Sphingobacteriia	ppiA		3.2.1.4,5.2.1.8	ko:K01179,ko:K01802,ko:K03767,ko:K03768,ko:K08738	ko00500,ko00920,ko01100,ko01120,ko01503,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04217,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01503,map01524,map02020,map04115,map04210,map04214,map04215,map04217,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko03110,ko04147	3.D.4.6	GH5,GH9		Bacteria	1IQXS@117747,4NGT6@976,COG0652@1,COG0652@2,COG3291@1,COG3291@2	NA|NA|NA	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MAG.T21.45_00670	1408473.JHXO01000010_gene3756	3e-116	425.2	Bacteroidia	wecB		5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	2FNQP@200643,4NGBD@976,COG0381@1,COG0381@2	NA|NA|NA	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MAG.T21.45_00671	709991.Odosp_0940	1.9e-40	172.2	Porphyromonadaceae			5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000				Bacteria	230U0@171551,2FMY0@200643,4NNHR@976,COG2148@1,COG2148@2	NA|NA|NA	M	Bacterial sugar transferase
MAG.T21.45_00672	105559.Nwat_0657	5.5e-89	334.7	Chromatiales	wbpU		2.4.1.52	ko:K00712					ko00000,ko01000,ko01003		GT4		Bacteria	1N0DG@1224,1S0D6@1236,1WY3U@135613,COG0438@1,COG0438@2	NA|NA|NA	M	PFAM Glycosyl transferase, group 1
MAG.T21.45_00673	1279019.ARQK01000054_gene241	2e-31	143.7	Gammaproteobacteria													Bacteria	1NY5M@1224,1SQSE@1236,COG1807@1,COG1807@2	NA|NA|NA	M	Dolichyl-phosphate-mannose-protein mannosyltransferase
MAG.T21.45_00674	1123399.AQVE01000011_gene1295	6.5e-191	674.1	Thiotrichales	asnB		6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110		R00578	RC00010	ko00000,ko00001,ko01000,ko01002				Bacteria	1MW4E@1224,1RQ7D@1236,460E6@72273,COG0367@1,COG0367@2	NA|NA|NA	E	Asparagine synthase, glutamine-hydrolyzing
MAG.T21.45_00675	533247.CRD_00151	1.8e-68	266.2	Nostocales													Bacteria	1GBCJ@1117,1HTJK@1161,COG0500@1,COG2226@2	NA|NA|NA	Q	methyltransferase
MAG.T21.45_00676	472759.Nhal_0700	2.7e-48	199.5	Chromatiales	wbpT			ko:K13003					ko00000,ko01000,ko01003,ko01005		GT4		Bacteria	1MU9C@1224,1RRWX@1236,1WYF9@135613,COG0438@1,COG0438@2	NA|NA|NA	M	PFAM Glycosyl transferase, group 1
MAG.T21.45_00677	1279009.ADICEAN_01142	1.4e-72	280.4	Cytophagia			2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100		R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003		GT39		Bacteria	47TMF@768503,4NPHN@976,COG1928@1,COG1928@2	NA|NA|NA	O	C-terminal four TMM region of protein-O-mannosyltransferase
MAG.T21.45_00679	1121889.AUDM01000003_gene2388	4.3e-63	248.1	Flavobacterium													Bacteria	1HYP0@117743,2NUIE@237,4NJXV@976,COG2227@1,COG2227@2	NA|NA|NA	H	AdoMet dependent proline di-methyltransferase
MAG.T21.45_00680	269798.CHU_3003	3.7e-91	341.3	Cytophagia													Bacteria	47KDC@768503,4NF0S@976,COG1215@1,COG1215@2	NA|NA|NA	M	Glycosyl transferase family 2
MAG.T21.45_00681	269797.Mbar_A1128	4.5e-19	102.4	Methanomicrobia													Archaea	2NBP5@224756,2XV5R@28890,COG0438@1,arCOG01410@2157	NA|NA|NA	M	Glycosyl transferases group 1
MAG.T21.45_00682	925409.KI911562_gene139	1.2e-21	110.9	Sphingobacteriia			3.1.21.3	ko:K01153,ko:K05789,ko:K07011,ko:K16554	ko05111,map05111				ko00000,ko00001,ko01000,ko01005,ko02000,ko02048	8.A.3.1			Bacteria	1INN0@117747,4NH8F@976,COG3206@1,COG3206@2	NA|NA|NA	M	lipopolysaccharide biosynthesis protein
MAG.T21.45_00683	762903.Pedsa_3227	7.6e-129	468.4	Sphingobacteriia	kpsD_2			ko:K01991	ko02026,map02026				ko00000,ko00001,ko02000	1.B.18			Bacteria	1IPNG@117747,4NEXJ@976,COG1596@1,COG1596@2	NA|NA|NA	M	export protein
MAG.T21.45_00684	755178.Cyan10605_1076	9.2e-43	180.6	Bacteria	wbyL			ko:K13002					ko00000,ko01000,ko01003,ko01005		GT2		Bacteria	COG1215@1,COG1215@2	NA|NA|NA	M	transferase activity, transferring glycosyl groups
MAG.T21.45_00685	700598.Niako_6781	9.3e-133	480.7	Sphingobacteriia				ko:K00612					ko00000,ko01000				Bacteria	1IWJ0@117747,4NEV9@976,COG2192@1,COG2192@2	NA|NA|NA	H	COGs COG2192 carbamoyl transferase NodU family
MAG.T21.45_00686	760192.Halhy_2893	1.1e-61	243.8	Sphingobacteriia	rfbU												Bacteria	1IT1I@117747,4PG4H@976,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferases group 1
MAG.T21.45_00688	1123248.KB893314_gene3340	4.3e-49	202.2	Bacteroidetes													Bacteria	4NMHA@976,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferases group 1
MAG.T21.45_00689	762903.Pedsa_2328	4.8e-36	158.7	Bacteria													Bacteria	COG0438@1,COG0438@2	NA|NA|NA	M	transferase activity, transferring glycosyl groups
MAG.T21.45_00690	1173024.KI912149_gene4999	5.5e-32	145.2	Stigonemataceae													Bacteria	1G0EC@1117,1JKT7@1189,28IRX@1,2Z8R5@2	NA|NA|NA		
MAG.T21.45_00691	761193.Runsl_0776	2.4e-165	588.6	Cytophagia	capL			ko:K02474	ko00520,map00520		R06894	RC00291	ko00000,ko00001,ko01000,ko01005				Bacteria	47JKM@768503,4NDTW@976,COG0677@1,COG0677@2	NA|NA|NA	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MAG.T21.45_00692	641524.ADICYQ_3488	4.8e-124	451.1	Cytophagia	capI		5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100		R01385	RC00289	ko00000,ko00001,ko01000				Bacteria	47JU9@768503,4NEKA@976,COG0451@1,COG0451@2	NA|NA|NA	M	PFAM NAD dependent epimerase dehydratase family
MAG.T21.45_00693	1122179.KB890497_gene2749	2.8e-93	349.0	Sphingobacteriia	dinB	GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02346					ko00000,ko01000,ko03400				Bacteria	1INW1@117747,4NE9N@976,COG0389@1,COG0389@2	NA|NA|NA	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MAG.T21.45_00694	760192.Halhy_3796	1.3e-133	483.0	Sphingobacteriia													Bacteria	1IQFF@117747,4NFWE@976,COG0454@1,COG0456@2	NA|NA|NA	K	Psort location Cytoplasmic, score 8.96
MAG.T21.45_00695	616991.JPOO01000001_gene4423	2.5e-200	704.9	Arenibacter	ltrA_1												Bacteria	1HZPH@117743,23HVD@178469,4NHMS@976,COG3344@1,COG3344@2	NA|NA|NA	L	Group II intron, maturase-specific domain
MAG.T21.45_00696	760192.Halhy_6019	1.8e-290	1005.0	Sphingobacteriia													Bacteria	1IR5K@117747,4NE4U@976,COG3292@1,COG3292@2	NA|NA|NA	T	Two component regulator propeller
MAG.T21.45_00697	1288963.ADIS_1078	1.4e-221	775.8	Cytophagia													Bacteria	47N95@768503,4NEQC@976,COG0521@1,COG0521@2,COG4198@1,COG4198@2	NA|NA|NA	H	Starch-binding associating with outer membrane
MAG.T21.45_00698	1288963.ADIS_1077	0.0	1619.0	Cytophagia													Bacteria	47TAY@768503,4NDU8@976,COG1629@1,COG4771@2	NA|NA|NA	HP	TonB dependent receptor
MAG.T21.45_00699	761193.Runsl_3328	2e-78	299.3	Cytophagia	mltR												Bacteria	47KCW@768503,4NE6T@976,COG0662@1,COG0662@2,COG2207@1,COG2207@2	NA|NA|NA	K	Transcriptional regulator, AraC family
MAG.T21.45_00700	760192.Halhy_0503	1.7e-31	141.7	Bacteria													Bacteria	COG1396@1,COG1396@2	NA|NA|NA	K	sequence-specific DNA binding
MAG.T21.45_00701	760192.Halhy_0504	1.2e-169	602.8	Sphingobacteriia	hipA		2.7.11.1	ko:K07154					ko00000,ko01000,ko01001,ko02048				Bacteria	1IUS6@117747,4NFYY@976,COG3550@1,COG3550@2	NA|NA|NA	S	Pfam:HipA_N
MAG.T21.45_00702	491205.JARQ01000004_gene2486	1.6e-98	365.9	Bacteroidetes	vdlC												Bacteria	4PKR6@976,COG0300@1,COG0300@2	NA|NA|NA	S	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAG.T21.45_00704	760192.Halhy_0544	5.6e-108	397.5	Sphingobacteriia													Bacteria	1IR1G@117747,4NDYY@976,COG2207@1,COG2207@2	NA|NA|NA	K	Transcriptional regulator araC family
MAG.T21.45_00705	1250006.JHZZ01000001_gene48	6.6e-119	434.1	Flavobacteriia				ko:K07133					ko00000				Bacteria	1HYQ4@117743,4NE39@976,COG1373@1,COG1373@2	NA|NA|NA	S	ATPase (AAA superfamily)
MAG.T21.45_00706	305900.GV64_24125	5.4e-228	797.3	Oceanospirillales			3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110		R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000		GH3		Bacteria	1N0Q4@1224,1RNK6@1236,1XNYF@135619,COG1472@1,COG1472@2	NA|NA|NA	G	Glycosyl hydrolase family 3 C-terminal domain
MAG.T21.45_00707	1239962.C943_01445	1.8e-95	355.9	Bacteroidetes													Bacteria	4NK36@976,COG1502@1,COG1502@2	NA|NA|NA	I	ORF6N domain
MAG.T21.45_00709	761193.Runsl_4585	3.4e-103	381.7	Cytophagia													Bacteria	47JDZ@768503,4NHGS@976,COG1278@1,COG1278@2,COG1432@1,COG1432@2	NA|NA|NA	K	NYN domain
MAG.T21.45_00710	760192.Halhy_R0059	1.5e-124	453.0	Sphingobacteriia	sdh		1.5.1.7,1.5.1.8,1.5.1.9	ko:K00290,ko:K14157	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R00716,R02313	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000				Bacteria	1IWHP@117747,4NF46@976,COG0686@1,COG0686@2	NA|NA|NA	E	Alanine dehydrogenase/PNT, N-terminal domain
MAG.T21.45_00711	865861.AZSU01000001_gene510	2.6e-92	345.5	Clostridiaceae			4.1.3.16,4.3.3.7	ko:K01714,ko:K18123	ko00261,ko00300,ko00330,ko00630,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map00630,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00470,R00471,R10147	RC00307,RC00308,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPSG@1239,249ZX@186801,36GI0@31979,COG0329@1,COG0329@2	NA|NA|NA	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MAG.T21.45_00712	485918.Cpin_1960	2.6e-32	144.8	Sphingobacteriia			3.1.26.11	ko:K00784	ko03013,map03013				ko00000,ko00001,ko01000,ko03016				Bacteria	1ITAW@117747,4NSDH@976,COG5646@1,COG5646@2	NA|NA|NA	S	Domain of unknown function (DU1801)
MAG.T21.45_00713	388413.ALPR1_11330	9.2e-125	453.8	Cytophagia													Bacteria	47JN9@768503,4NGQK@976,COG4932@1,COG4932@2	NA|NA|NA	M	Domain of unknown function (DUF3472)
MAG.T21.45_00714	1122179.KB890441_gene1069	1.2e-151	543.9	Sphingobacteriia													Bacteria	1IR9W@117747,4NGZV@976,COG3291@1,COG3291@2	NA|NA|NA	U	PFAM PKD domain
MAG.T21.45_00715	1122176.KB903543_gene624	2.4e-35	155.2	Bacteroidetes													Bacteria	2E598@1,3301J@2,4NUX7@976	NA|NA|NA		
MAG.T21.45_00716	760192.Halhy_6242	6.5e-112	410.6	Sphingobacteriia	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K03566,ko:K13713	ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000,ko03000				Bacteria	1INM8@117747,4NF1Z@976,COG0152@1,COG0152@2	NA|NA|NA	F	Phosphoribosylaminoimidazolesuccinocarboxamide synthase
MAG.T21.45_00717	760192.Halhy_1203	2.2e-224	786.9	Bacteroidetes			3.2.1.4,5.2.1.8	ko:K01179,ko:K03768,ko:K08738	ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko03110	3.D.4.6	GH5,GH9		Bacteria	4NDZC@976,COG3291@1,COG3291@2	NA|NA|NA	DZ	Pkd domain containing protein
MAG.T21.45_00718	1120965.AUBV01000003_gene587	2.3e-09	69.3	Cytophagia													Bacteria	28NMY@1,2ZBNE@2,47PGY@768503,4NN50@976	NA|NA|NA		
MAG.T21.45_00719	760192.Halhy_4451	3.2e-187	662.1	Sphingobacteriia				ko:K02014					ko00000,ko02000	1.B.14			Bacteria	1IPNU@117747,4PKTE@976,COG4772@1,COG4772@2	NA|NA|NA	P	PFAM TonB-dependent Receptor
MAG.T21.45_00720	643867.Ftrac_3302	4.2e-28	131.3	Cytophagia	nadR												Bacteria	47QMU@768503,4NFNZ@976,COG3172@1,COG3172@2	NA|NA|NA	H	ATPase kinase involved in NAD metabolism
MAG.T21.45_00721	760192.Halhy_4453	5.6e-61	240.7	Sphingobacteriia													Bacteria	1IPH6@117747,28M4Q@1,2ZAIK@2,4NJC3@976	NA|NA|NA		
MAG.T21.45_00722	760192.Halhy_4454	3.5e-91	341.7	Sphingobacteriia	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113		ko:K03595,ko:K06883					ko00000,ko03009,ko03029				Bacteria	1INM6@117747,4NES2@976,COG1159@1,COG1159@2	NA|NA|NA	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MAG.T21.45_00723	760192.Halhy_1296	5.7e-191	673.7	Sphingobacteriia	der	GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363		ko:K03977					ko00000,ko03009				Bacteria	1IR18@117747,4NE2J@976,COG1160@1,COG1160@2	NA|NA|NA	S	GTPase that plays an essential role in the late steps of ribosome biogenesis
MAG.T21.45_00724	984262.SGRA_0903	1.2e-57	229.6	Sphingobacteriia	rfbC		5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000				Bacteria	1IRUX@117747,4NNKW@976,COG1898@1,COG1898@2	NA|NA|NA	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MAG.T21.45_00725	1313421.JHBV01000014_gene3881	7.6e-70	270.8	Sphingobacteriia	rfbD		1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000				Bacteria	1IP3S@117747,4NE3K@976,COG1091@1,COG1091@2	NA|NA|NA	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MAG.T21.45_00726	760192.Halhy_4460	2.3e-301	1041.6	Bacteroidetes			1.7.2.1,3.2.1.4,5.2.1.8	ko:K00368,ko:K01179,ko:K03768,ko:K08738	ko00500,ko00910,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00910,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00529,M00595	R00783,R00785,R06200,R10151,R11307,R11308	RC00086,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko03110	3.D.4.6	GH5,GH9		Bacteria	4NFCW@976,COG2132@1,COG2132@2,COG3291@1,COG3291@2	NA|NA|NA	M	C-terminal domain of CHU protein family
MAG.T21.45_00727	760192.Halhy_1301	1.9e-64	252.3	Sphingobacteriia	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000			iYO844.BSU23270	Bacteria	1IPZJ@117747,4NHI8@976,COG0307@1,COG0307@2	NA|NA|NA	H	riboflavin synthase, alpha subunit
MAG.T21.45_00728	760192.Halhy_4687	3.6e-311	1073.9	Sphingobacteriia				ko:K14054					ko00000				Bacteria	1IURB@117747,4NEJA@976,COG2866@1,COG2866@2	NA|NA|NA	E	Zinc carboxypeptidase
MAG.T21.45_00729	1122176.KB903549_gene1276	3.7e-161	574.7	Sphingobacteriia													Bacteria	1ITWD@117747,4NGC0@976,COG2072@1,COG2072@2	NA|NA|NA	P	flavoprotein involved in K transport
MAG.T21.45_00730	760192.Halhy_4464	7.3e-93	347.1	Sphingobacteriia													Bacteria	1IR0M@117747,4NE45@976,COG1028@1,COG1028@2	NA|NA|NA	IQ	short-chain dehydrogenase
MAG.T21.45_00731	760192.Halhy_4465	5.2e-184	651.0	Sphingobacteriia	fadD		6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1			Bacteria	1IWU5@117747,4NEA4@976,COG1022@1,COG1022@2	NA|NA|NA	I	AMP-binding enzyme
MAG.T21.45_00732	760192.Halhy_4468	3.7e-143	515.0	Sphingobacteriia	alkH		1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPD9@117747,4NGHD@976,COG1012@1,COG1012@2	NA|NA|NA	C	Belongs to the aldehyde dehydrogenase family
MAG.T21.45_00733	1280689.AUJC01000009_gene3457	9.2e-43	180.6	Clostridiaceae				ko:K07124					ko00000				Bacteria	1UZHA@1239,248C8@186801,36IDY@31979,COG0300@1,COG0300@2	NA|NA|NA	S	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAG.T21.45_00736	760192.Halhy_1316	3.2e-71	275.4	Sphingobacteriia	gnnA			ko:K09949					ko00000			iAF987.Gmet_2352	Bacteria	1IX1W@117747,4NEC6@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_00737	1121904.ARBP01000001_gene5425	2.5e-22	112.1	Cytophagia													Bacteria	2DNRU@1,32YUJ@2,47SHV@768503,4NVE3@976	NA|NA|NA		
MAG.T21.45_00738	1121104.AQXH01000001_gene1807	1.8e-162	579.3	Sphingobacteriia													Bacteria	1IQ41@117747,4NF5T@976,COG2866@1,COG2866@2	NA|NA|NA	E	Peptidase M14, carboxypeptidase A
MAG.T21.45_00739	760192.Halhy_5370	1.7e-129	469.5	Sphingobacteriia	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000			iLJ478.TM0166,iSB619.SA_RS08370	Bacteria	1IQU2@117747,4NES8@976,COG0285@1,COG0285@2	NA|NA|NA	H	Belongs to the folylpolyglutamate synthase family
MAG.T21.45_00740	760192.Halhy_5371	4.3e-22	112.1	Sphingobacteriia				ko:K03646,ko:K03832					ko00000,ko02000	2.C.1.1,2.C.1.2			Bacteria	1IQ45@117747,4NG4I@976,COG0810@1,COG0810@2	NA|NA|NA	M	TonB family domain protein
MAG.T21.45_00741	760192.Halhy_5372	1.8e-26	125.6	Sphingobacteriia	exbD			ko:K03559					ko00000,ko02000	1.A.30.2.1			Bacteria	1IZHU@117747,4NNI6@976,COG0848@1,COG0848@2	NA|NA|NA	U	Biopolymer transport protein ExbD/TolR
MAG.T21.45_00742	1122176.KB903531_gene2966	1.5e-28	132.5	Bacteria				ko:K03559					ko00000,ko02000	1.A.30.2.1			Bacteria	COG0848@1,COG0848@2	NA|NA|NA	U	biopolymer transport protein
MAG.T21.45_00743	760192.Halhy_5374	2.8e-75	288.5	Sphingobacteriia	exbB			ko:K03561					ko00000,ko02000	1.A.30.2.1			Bacteria	1IQAP@117747,4NFIX@976,COG0811@1,COG0811@2	NA|NA|NA	U	PFAM MotA TolQ ExbB proton channel
MAG.T21.45_00744	760192.Halhy_5359	2.1e-54	219.2	Bacteroidetes													Bacteria	4PP1X@976,COG0463@1,COG0463@2	NA|NA|NA	M	Glycosyl transferase family 2
MAG.T21.45_00745	1122176.KB903536_gene1838	0.0	1186.8	Sphingobacteriia	fadB		1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782,ko:K07516	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04743,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000			iYO844.BSU32840	Bacteria	1IPN0@117747,4NF9D@976,COG1024@1,COG1024@2,COG1250@1,COG1250@2	NA|NA|NA	I	3-hydroxyacyl-CoA dehydrogenase
MAG.T21.45_00746	760192.Halhy_5377	5.2e-167	594.0	Sphingobacteriia	fadA		2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000				Bacteria	1INYF@117747,4NE3Q@976,COG0183@1,COG0183@2	NA|NA|NA	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
MAG.T21.45_00747	760192.Halhy_1104	3.4e-296	1025.4	Sphingobacteriia			2.7.11.1,3.2.1.4,3.2.1.50,5.2.1.8	ko:K01179,ko:K01205,ko:K03768,ko:K07004,ko:K08738,ko:K12132	ko00500,ko00531,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04142,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00531,map00920,map01100,map01120,map01524,map02020,map04115,map04142,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00078,M00595	R06200,R07816,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko01001,ko03110,ko04147	3.D.4.6	GH5,GH9		Bacteria	1ISXD@117747,4NDZC@976,COG1470@1,COG1470@2,COG3291@1,COG3291@2,COG4886@1,COG4886@2	NA|NA|NA	M	C-terminal domain of CHU protein family
MAG.T21.45_00748	760192.Halhy_1103	7.2e-96	357.5	Bacteria													Bacteria	COG3064@1,COG3064@2	NA|NA|NA	M	translation initiation factor activity
MAG.T21.45_00749	760192.Halhy_0166	9.6e-143	513.5	Sphingobacteriia				ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1IR94@117747,4NECN@976,COG0577@1,COG0577@2	NA|NA|NA	V	ABC-type antimicrobial peptide transport system, permease component
MAG.T21.45_00750	760192.Halhy_0165	8.7e-153	546.6	Sphingobacteriia	queA		2.4.99.17	ko:K07568					ko00000,ko01000,ko03016				Bacteria	1INNG@117747,4NF2T@976,COG0809@1,COG0809@2	NA|NA|NA	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MAG.T21.45_00751	1122176.KB903609_gene5243	1.1e-30	138.7	Sphingobacteriia													Bacteria	1ITH1@117747,2C8VT@1,32RN1@2,4NS78@976	NA|NA|NA	S	Protein of unknown function (DUF2795)
MAG.T21.45_00752	1346330.M472_04810	1.6e-56	226.1	Sphingobacteriia	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.19,2.7.4.25,6.3.2.1	ko:K00800,ko:K00945,ko:K03977,ko:K13799	ko00240,ko00400,ko00410,ko00770,ko01100,ko01110,ko01130,ko01230,map00240,map00400,map00410,map00770,map01100,map01110,map01130,map01230	M00022,M00052,M00119	R00158,R00512,R01665,R02473,R03460	RC00002,RC00096,RC00141,RC00350	ko00000,ko00001,ko00002,ko01000,ko03009				Bacteria	1IRY5@117747,4NEMB@976,COG0283@1,COG0283@2	NA|NA|NA	F	Belongs to the cytidylate kinase family. Type 1 subfamily
MAG.T21.45_00755	760192.Halhy_5543	5.1e-111	407.5	Sphingobacteriia	rpoD			ko:K03086					ko00000,ko03021				Bacteria	1INNM@117747,4NEBF@976,COG0568@1,COG0568@2	NA|NA|NA	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MAG.T21.45_00756	580340.Tlie_1160	1.6e-123	449.5	Synergistetes	csd												Bacteria	3TAAX@508458,COG0520@1,COG0520@2	NA|NA|NA	E	TIGRFAM cysteine desulfurase family protein, VC1184 subfamily
MAG.T21.45_00757	1120965.AUBV01000005_gene1559	3.7e-127	462.2	Cytophagia				ko:K02014					ko00000,ko02000	1.B.14			Bacteria	47P5E@768503,4NHH8@976,COG4206@1,COG4206@2	NA|NA|NA	H	TonB dependent receptor
MAG.T21.45_00758	1122179.KB890435_gene957	0.0	1325.1	Bacteroidetes													Bacteria	4NESU@976,COG4447@1,COG4447@2	NA|NA|NA	T	PFAM BNR Asp-box repeat
MAG.T21.45_00759	760192.Halhy_5529	1.2e-235	822.4	Sphingobacteriia				ko:K01436,ko:K12941					ko00000,ko01000,ko01002				Bacteria	1IPEX@117747,4NEKH@976,COG1473@1,COG1473@2	NA|NA|NA	S	Peptidase dimerisation domain
MAG.T21.45_00760	1122176.KB903542_gene391	2.1e-147	529.3	Sphingobacteriia			2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000				Bacteria	1IZG5@117747,4NGCA@976,COG3425@1,COG3425@2	NA|NA|NA	I	Hydroxymethylglutaryl-coenzyme A synthase C terminal
MAG.T21.45_00761	485918.Cpin_1287	3.1e-36	159.1	Sphingobacteriia	comEA			ko:K02237		M00429			ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2			Bacteria	1ISN7@117747,4NK4K@976,COG1555@1,COG1555@2	NA|NA|NA	L	DNA uptake protein and related DNA-binding
MAG.T21.45_00762	575590.HMPREF0156_00104	6.9e-42	179.1	Bacteroidetes	comEC			ko:K02238		M00429			ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2			Bacteria	4NEJH@976,COG0658@1,COG0658@2	NA|NA|NA	S	ComEC Rec2-related protein
MAG.T21.45_00763	1122176.KB903545_gene857	2.1e-36	159.1	Sphingobacteriia			2.3.1.128	ko:K03790					ko00000,ko01000,ko03009				Bacteria	1IYVQ@117747,4NV0H@976,COG1670@1,COG1670@2	NA|NA|NA	J	Acetyltransferase (GNAT) domain
MAG.T21.45_00766	760192.Halhy_2936	1.8e-130	472.6	Sphingobacteriia				ko:K07263					ko00000,ko01000,ko01002				Bacteria	1INSD@117747,4NEDZ@976,COG0612@1,COG0612@2	NA|NA|NA	S	Peptidase M16
MAG.T21.45_00767	760192.Halhy_2599	4.3e-104	385.2	Sphingobacteriia													Bacteria	1IT79@117747,4NEX3@976,COG0526@1,COG0526@2	NA|NA|NA	O	PFAM AhpC TSA family
MAG.T21.45_00769	1122605.KB893626_gene2583	4e-55	222.2	Sphingobacteriia													Bacteria	1IPRP@117747,4NG9C@976,COG1215@1,COG1215@2	NA|NA|NA	M	PFAM Glycosyl transferase family 2
MAG.T21.45_00770	760192.Halhy_3815	4.3e-241	840.5	Sphingobacteriia	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02837,ko:K07133					ko00000,ko03012				Bacteria	1IP50@117747,4NFEZ@976,COG4108@1,COG4108@2	NA|NA|NA	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MAG.T21.45_00771	1313421.JHBV01000008_gene4352	2e-54	219.2	Sphingobacteriia													Bacteria	1IT7A@117747,4NEUA@976,COG1309@1,COG1309@2	NA|NA|NA	K	Transcriptional regulator, TetR family
MAG.T21.45_00773	1122176.KB903547_gene1111	5.6e-149	535.8	Bacteroidetes													Bacteria	4NDU9@976,COG3291@1,COG3291@2	NA|NA|NA	M	C-terminal domain of CHU protein family
MAG.T21.45_00774	1122176.KB903547_gene1111	9.2e-148	531.6	Bacteroidetes													Bacteria	4NDU9@976,COG3291@1,COG3291@2	NA|NA|NA	M	C-terminal domain of CHU protein family
MAG.T21.45_00775	760192.Halhy_2640	8e-77	295.4	Bacteria				ko:K21218	ko02040,map02040				ko00000,ko00001,ko02000,ko02035	1.A.30.1			Bacteria	COG0457@1,COG0457@2,COG2885@1,COG2885@2	NA|NA|NA	M	chlorophyll binding
MAG.T21.45_00776	1122176.KB903535_gene1892	1.9e-59	236.5	Sphingobacteriia				ko:K06076					ko00000,ko02000	1.B.9			Bacteria	1IQ3Y@117747,4NIU4@976,COG2067@1,COG2067@2	NA|NA|NA	I	protein CHP03519, membrane, Bacteroidetes
MAG.T21.45_00777	102232.GLO73106DRAFT_00026910	3.9e-25	122.5	Cyanobacteria				ko:K11016	ko03070,map03070				ko00000,ko00001,ko02042,ko02044				Bacteria	1GC1J@1117,COG2931@1,COG2931@2,COG3210@1,COG3210@2,COG3291@1,COG3291@2	NA|NA|NA	QU	Polymorphic membrane protein, Chlamydia
MAG.T21.45_00778	1122176.KB903565_gene3405	6.6e-112	410.6	Sphingobacteriia	tdcB		4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000				Bacteria	1IUV5@117747,4NEY2@976,COG1171@1,COG1171@2	NA|NA|NA	E	Pyridoxal-phosphate dependent enzyme
MAG.T21.45_00779	760192.Halhy_2661	5.1e-94	351.7	Sphingobacteriia	dacB	GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006508,GO:0006807,GO:0007049,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009987,GO:0016043,GO:0016787,GO:0016998,GO:0017171,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0030203,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0032505,GO:0033218,GO:0033293,GO:0036094,GO:0042597,GO:0043093,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044464,GO:0045229,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0097159,GO:0140096,GO:1901135,GO:1901136,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901681	3.4.16.4	ko:K07259	ko00550,map00550				ko00000,ko00001,ko01000,ko01002,ko01011			iAPECO1_1312.APECO1_3250,iECOK1_1307.ECOK1_3603,iECS88_1305.ECS88_3564,iUMN146_1321.UM146_00470,iUTI89_1310.UTI89_C3615,iYL1228.KPN_03592	Bacteria	1INKX@117747,4NGIQ@976,COG2027@1,COG2027@2	NA|NA|NA	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C
MAG.T21.45_00780	760192.Halhy_2660	7.9e-162	577.4	Bacteroidetes													Bacteria	4PKDG@976,COG1680@1,COG1680@2	NA|NA|NA	V	COG1680 Beta-lactamase class C and other penicillin binding
MAG.T21.45_00782	760192.Halhy_2939	3e-64	251.5	Sphingobacteriia				ko:K03088					ko00000,ko03021				Bacteria	1J06N@117747,4NPSM@976,COG1595@1,COG1595@2	NA|NA|NA	K	ECF sigma factor
MAG.T21.45_00783	760192.Halhy_2150	1.2e-35	156.0	Sphingobacteriia													Bacteria	1ISQF@117747,29D8R@1,3006P@2,4NNGD@976	NA|NA|NA		
MAG.T21.45_00784	760192.Halhy_2098	0.0	1760.7	Sphingobacteriia	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0030312,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13,2.1.1.245,2.1.1.258	ko:K00197,ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00680,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00680,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00357,M00377,M00422	R00946,R02289,R09096,R09365,R10219,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000			iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545	Bacteria	1IR6C@117747,4NFRF@976,COG0646@1,COG0646@2,COG1410@1,COG1410@2	NA|NA|NA	E	Methionine synthase
MAG.T21.45_00785	1122176.KB903552_gene3682	4.9e-78	297.7	Sphingobacteriia	gip		5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100		R01394	RC00511	ko00000,ko00001,ko01000				Bacteria	1INUU@117747,4NG0V@976,COG3622@1,COG3622@2	NA|NA|NA	G	Hydroxypyruvate isomerase
MAG.T21.45_00786	1166018.FAES_0841	4e-25	121.7	Cytophagia													Bacteria	28KSE@1,2ZBRS@2,47P8I@768503,4NNCR@976	NA|NA|NA	S	Gluconate 2-dehydrogenase subunit 3
MAG.T21.45_00787	1122176.KB903543_gene651	6.1e-233	813.5	Sphingobacteriia													Bacteria	1IPA2@117747,4NEF2@976,COG2303@1,COG2303@2	NA|NA|NA	E	Oxidoreductase
MAG.T21.45_00788	760192.Halhy_2507	0.0	1239.2	Sphingobacteriia	acnA		4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1INUB@117747,4NDZT@976,COG1048@1,COG1048@2	NA|NA|NA	C	aconitate hydratase
MAG.T21.45_00790	760192.Halhy_3898	3.2e-214	752.3	Bacteria	recB		3.6.4.12	ko:K16898					ko00000,ko01000,ko03400				Bacteria	COG1074@1,COG1074@2	NA|NA|NA	L	ATP-dependent DNA helicase activity
MAG.T21.45_00791	1185876.BN8_06312	4e-31	141.4	Cytophagia													Bacteria	47XVC@768503,4NRSP@976,COG2318@1,COG2318@2	NA|NA|NA	S	DinB family
MAG.T21.45_00792	1267211.KI669560_gene1019	6.2e-38	164.5	Sphingobacteriia	ydcC												Bacteria	1IZ7F@117747,4NHV3@976,COG2834@1,COG2834@2	NA|NA|NA	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MAG.T21.45_00793	760192.Halhy_5172	3.6e-62	247.3	Bacteroidetes													Bacteria	4PMJA@976,COG3210@1,COG3210@2	NA|NA|NA	U	domain, Protein
MAG.T21.45_00794	1267211.KI669560_gene2162	4.6e-218	764.2	Sphingobacteriia	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931		R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002			iAF987.Gmet_1487	Bacteria	1IPQZ@117747,4NE8Q@976,COG0449@1,COG0449@2	NA|NA|NA	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MAG.T21.45_00795	925409.KI911562_gene2942	6.7e-216	757.3	Sphingobacteriia	apcE	GO:0005575,GO:0005622,GO:0005623,GO:0009579,GO:0016020,GO:0034357,GO:0042651,GO:0044424,GO:0044436,GO:0044464	2.7.7.24	ko:K00973,ko:K02096,ko:K02286,ko:K02290,ko:K05378,ko:K05379,ko:K05380	ko00196,ko00521,ko00523,ko00525,ko01100,ko01130,map00196,map00521,map00523,map00525,map01100,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko00194,ko01000				Bacteria	1IPMM@117747,4PKFG@976,COG0448@1,COG0448@2	NA|NA|NA	G	Domain of unknown function (DUF4954)
MAG.T21.45_00797	411468.CLOSCI_02121	1.5e-13	82.0	Lachnoclostridium													Bacteria	1TP7Q@1239,21ZRE@1506553,24A19@186801,COG4804@1,COG4804@2	NA|NA|NA	S	Psort location Cytoplasmic, score 8.87
MAG.T21.45_00798	1305737.JAFX01000001_gene1343	6.1e-43	180.6	Bacteroidetes	merR												Bacteria	4NQCR@976,COG3620@1,COG3620@2	NA|NA|NA	K	transcriptional regulator
MAG.T21.45_00799	760192.Halhy_3112	6.5e-13	79.7	Bacteroidetes													Bacteria	2AE47@1,313XF@2,4NYMZ@976	NA|NA|NA	S	Domain of unknown function (DUF4160)
MAG.T21.45_00800	755732.Fluta_3066	3.5e-40	171.8	Flavobacteriia													Bacteria	1IIQG@117743,29C3H@1,32VP8@2,4NXVV@976	NA|NA|NA		
MAG.T21.45_00801	755732.Fluta_3065	6.3e-98	364.0	Flavobacteriia				ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1HZNH@117743,4NICG@976,COG1277@1,COG1277@2	NA|NA|NA	S	ABC-2 family transporter protein
MAG.T21.45_00802	755732.Fluta_3064	3.3e-100	371.7	Flavobacteriia				ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1HY13@117743,4NFNM@976,COG1131@1,COG1131@2	NA|NA|NA	V	abc transporter (atp-binding protein)
MAG.T21.45_00803	313595.P700755_003990	6.6e-15	87.4	Flavobacteriia													Bacteria	1I2MW@117743,2E78C@1,331S1@2,4NPWT@976	NA|NA|NA		
MAG.T21.45_00804	1150600.ADIARSV_1580	2.1e-83	318.2	Sphingobacteriia			4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024		R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000				Bacteria	1ISWY@117747,4NHDQ@976,COG3656@1,COG3656@2,COG4677@1,COG4677@2	NA|NA|NA	G	Fibronectin type 3 domain
MAG.T21.45_00806	938709.AUSH02000020_gene1986	1.9e-62	247.7	Bacteroidetes													Bacteria	4NHDQ@976,COG3656@1,COG3656@2,COG5295@1,COG5295@2	NA|NA|NA	UW	fibronectin type III domain protein
MAG.T21.45_00807	926559.JoomaDRAFT_1666	4.3e-25	120.2	Flavobacteriia													Bacteria	1HZV0@117743,4NGWM@976,COG1075@1,COG1075@2	NA|NA|NA	S	Domain of unknown function(DUF2779)
MAG.T21.45_00808	1444712.BN1013_00371	3.8e-73	281.6	Bacteria													Bacteria	COG0553@1,COG0553@2	NA|NA|NA	L	helicase activity
MAG.T21.45_00813	1308863.U5J9H1_9CAUD	4.9e-16	90.9	Siphoviridae													Viruses	4QGC4@10239,4QMZZ@10699,4QUBS@28883,4QW9I@35237	NA|NA|NA		
MAG.T21.45_00816	760192.Halhy_2958	3e-133	481.9	Sphingobacteriia	obg	GO:0000003,GO:0000160,GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007059,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019538,GO:0019954,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0034622,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0040007,GO:0042254,GO:0042255,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0043933,GO:0043934,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1990904		ko:K03979					ko00000,ko01000,ko03009				Bacteria	1IP1F@117747,4NEK4@976,COG0536@1,COG0536@2	NA|NA|NA	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MAG.T21.45_00817	1122176.KB903546_gene1040	1.8e-64	252.3	Sphingobacteriia	adk		2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1IRJW@117747,4NG7J@976,COG0563@1,COG0563@2	NA|NA|NA	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MAG.T21.45_00818	760192.Halhy_2960	2.1e-24	119.4	Sphingobacteriia													Bacteria	1ITXU@117747,4NUNS@976,COG0791@1,COG0791@2	NA|NA|NA	M	COGs COG0791 Cell wall-associated hydrolase (invasion-associated protein)
MAG.T21.45_00819	760192.Halhy_2664	8.7e-62	243.8	Sphingobacteriia	yafV		3.5.1.3	ko:K13566	ko00250,map00250		R00269,R00348	RC00010	ko00000,ko00001,ko01000				Bacteria	1INZJ@117747,4NE37@976,COG0388@1,COG0388@2	NA|NA|NA	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MAG.T21.45_00820	760192.Halhy_4166	2.5e-61	241.9	Sphingobacteriia	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02897	ko03010,map03010	M00178			ko00000,ko00001,ko00002,ko03011				Bacteria	1IST6@117747,4NEN6@976,COG1825@1,COG1825@2	NA|NA|NA	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MAG.T21.45_00821	760192.Halhy_4165	1.6e-137	495.7	Sphingobacteriia	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000			iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iLJ478.TM1628,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665	Bacteria	1INUM@117747,4NEVF@976,COG0462@1,COG0462@2	NA|NA|NA	EF	Ribose-phosphate pyrophosphokinase
MAG.T21.45_00822	760192.Halhy_2713	2.7e-129	468.4	Sphingobacteriia	ispB	GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110		R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006			iYL1228.KPN_03597,ic_1306.c3945	Bacteria	1INM5@117747,4NET2@976,COG0142@1,COG0142@2	NA|NA|NA	H	Belongs to the FPP GGPP synthase family
MAG.T21.45_00823	760192.Halhy_2715	3e-184	651.4	Sphingobacteriia	glyA	GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000			iG2583_1286.G2583_3081,iIT341.HP0183	Bacteria	1IPUW@117747,4NE30@976,COG0112@1,COG0112@2	NA|NA|NA	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MAG.T21.45_00824	1122176.KB903547_gene1112	1.1e-39	171.4	Sphingobacteriia													Bacteria	1IWKW@117747,4NE8J@976,COG2885@1,COG2885@2	NA|NA|NA	M	Thrombospondin type 3 repeat
MAG.T21.45_00826	743722.Sph21_0279	3.8e-10	70.5	Sphingobacteriia	merP			ko:K07213,ko:K08364	ko04978,map04978				ko00000,ko00001,ko02000	1.A.72.1			Bacteria	1IUGG@117747,4NURN@976,COG2608@1,COG2608@2	NA|NA|NA	P	PFAM Heavy-metal-associated domain
MAG.T21.45_00827	1122176.KB903556_gene4101	1.2e-57	230.3	Sphingobacteriia													Bacteria	1IYJZ@117747,4NQN5@976,COG5653@1,COG5653@2	NA|NA|NA	M	Protein involved in cellulose biosynthesis
MAG.T21.45_00829	1046627.BZARG_1698	3.5e-23	115.5	Flavobacteriia													Bacteria	1I4ZP@117743,2E380@1,32Y7Q@2,4NU3D@976	NA|NA|NA	S	Protein of unknown function (Porph_ging)
MAG.T21.45_00830	1313301.AUGC01000017_gene790	1.1e-26	129.0	Bacteroidetes													Bacteria	4NF6X@976,COG1629@1,COG1629@2	NA|NA|NA	P	transport
MAG.T21.45_00831	1123248.KB893314_gene3477	1.2e-100	373.6	Sphingobacteriia	norM			ko:K03327					ko00000,ko02000	2.A.66.1			Bacteria	1IPQM@117747,4NEBB@976,COG0534@1,COG0534@2	NA|NA|NA	V	efflux protein, MATE family
MAG.T21.45_00832	762903.Pedsa_0563	1.7e-87	329.3	Sphingobacteriia													Bacteria	1IP7R@117747,4NG8R@976,COG1028@1,COG1028@2	NA|NA|NA	IQ	Short-chain dehydrogenase reductase sdr
MAG.T21.45_00833	925409.KI911562_gene1641	2.7e-155	555.1	Bacteroidetes	uxuA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0008198,GO:0008927,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019585,GO:0019752,GO:0030145,GO:0032787,GO:0042839,GO:0042840,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0046914,GO:0071704,GO:0072329,GO:1901575	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000				Bacteria	4NFA5@976,COG1312@1,COG1312@2	NA|NA|NA	G	Catalyzes the dehydration of D-mannonate
MAG.T21.45_00834	1158294.JOMI01000007_gene217	3e-158	564.7	Bacteroidia			2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	2FMY2@200643,4NFH8@976,COG0524@1,COG0524@2	NA|NA|NA	G	Kinase, PfkB family
MAG.T21.45_00835	926549.KI421517_gene2820	1e-179	636.3	Cytophagia													Bacteria	47JBJ@768503,4NE7R@976,COG2271@1,COG2271@2	NA|NA|NA	G	PFAM Major Facilitator Superfamily
MAG.T21.45_00836	760192.Halhy_5401	9.3e-161	573.5	Bacteroidetes	fadD36	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087		ko:K12429,ko:K18660,ko:K18661,ko:K18662	ko00280,map00280		R03383	RC00004,RC00137	ko00000,ko00001,ko01000,ko01004				Bacteria	4NFPF@976,COG0318@1,COG0318@2	NA|NA|NA	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II
MAG.T21.45_00837	761193.Runsl_2170	4.4e-29	134.0	Cytophagia	madL												Bacteria	2CAQ0@1,32RRS@2,47QP4@768503,4NRRH@976	NA|NA|NA	S	Malonate transporter MadL subunit
MAG.T21.45_00838	761193.Runsl_2169	1.6e-76	292.7	Cytophagia	madM												Bacteria	28HGK@1,2Z7SE@2,47N9G@768503,4NGDR@976	NA|NA|NA	S	Malonate/sodium symporter MadM subunit
MAG.T21.45_00839	1122179.KB890419_gene99	1e-14	86.7	Bacteria													Bacteria	COG1629@1,COG1629@2	NA|NA|NA	P	transport
MAG.T21.45_00840	1286632.P278_26470	2e-104	385.6	Flavobacteriia	ygiD	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046566,GO:0051213,GO:0055114	1.13.11.8	ko:K04100,ko:K15777	ko00362,ko00624,ko00627,ko00965,ko01120,map00362,map00624,map00627,map00965,map01120		R01632,R03550,R04280,R08836,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000				Bacteria	1HX1P@117743,4NFGT@976,COG3384@1,COG3384@2	NA|NA|NA	S	in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine
MAG.T21.45_00841	1185876.BN8_06475	1.4e-44	186.0	Cytophagia													Bacteria	2EBMU@1,32VAF@2,47RMD@768503,4NTKE@976	NA|NA|NA		
MAG.T21.45_00842	1120965.AUBV01000003_gene279	3.8e-126	458.4	Cytophagia	gntT	GO:0003674,GO:0005215,GO:0005342,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008028,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015128,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015568,GO:0015672,GO:0015711,GO:0015718,GO:0015726,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0035429,GO:0042873,GO:0042879,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1902600,GO:1903825,GO:1905039		ko:K03299,ko:K06155,ko:K06157,ko:K16321					ko00000,ko02000	2.A.8,2.A.8.1.2,2.A.8.1.3,2.A.8.1.4		iHN637.CLJU_RS05690,iHN637.CLJU_RS13905,iSSON_1240.SSON_3547	Bacteria	47KJN@768503,4NFBD@976,COG2610@1,COG2610@2	NA|NA|NA	EG	TIGRFAM gluconate transporter
MAG.T21.45_00843	487796.Flav2ADRAFT_0924	6.5e-158	563.9	Flavobacteriia													Bacteria	1HY74@117743,4NE09@976,COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
MAG.T21.45_00845	1250232.JQNJ01000001_gene3904	3.9e-289	1001.1	Flavobacteriia													Bacteria	1HXFM@117743,4NDU8@976,COG1629@1,COG4206@1,COG4206@2,COG4771@2	NA|NA|NA	P	TonB-dependent receptor plug
MAG.T21.45_00846	1250232.JQNJ01000001_gene3905	1e-92	347.4	Flavobacteriia				ko:K21572					ko00000,ko02000	8.A.46.1,8.A.46.3			Bacteria	1I1AI@117743,4NHZS@976,COG0521@1,COG0521@2	NA|NA|NA	H	Starch-binding associating with outer membrane
MAG.T21.45_00847	1122176.KB903532_gene2630	4.1e-38	164.5	Sphingobacteriia													Bacteria	1IYMQ@117747,4NSE3@976,COG2010@1,COG2010@2	NA|NA|NA	C	Haem-binding domain
MAG.T21.45_00848	760192.Halhy_2074	4.3e-89	334.3	Sphingobacteriia				ko:K02003		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1IXHK@117747,4NE65@976,COG1136@1,COG1136@2	NA|NA|NA	V	ATPases associated with a variety of cellular activities
MAG.T21.45_00849	269798.CHU_2645	1e-64	253.8	Cytophagia				ko:K02005					ko00000				Bacteria	47PKJ@768503,4NMQ2@976,COG1566@1,COG1566@2	NA|NA|NA	V	HlyD family secretion protein
MAG.T21.45_00850	760192.Halhy_2072	3.8e-135	488.0	Sphingobacteriia	devC			ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1IVNC@117747,4NEIP@976,COG0577@1,COG0577@2	NA|NA|NA	V	FtsX-like permease family
MAG.T21.45_00851	760192.Halhy_2071	7e-51	208.4	Sphingobacteriia													Bacteria	1IPWM@117747,4NF4X@976,COG1538@1,COG1538@2	NA|NA|NA	MU	PFAM Outer membrane efflux protein
MAG.T21.45_00852	760192.Halhy_2395	1.5e-130	473.0	Sphingobacteriia													Bacteria	1IQ1I@117747,4NDZF@976,COG4299@1,COG4299@2	NA|NA|NA	S	Domain of unknown function (DUF5009)
MAG.T21.45_00853	518766.Rmar_2797	2e-187	662.9	Bacteroidetes Order II. Incertae sedis	chb_1		3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110		GH20		Bacteria	1FJXQ@1100069,4NE08@976,COG3525@1,COG3525@2	NA|NA|NA	G	Putative carbohydrate binding domain
MAG.T21.45_00854	1122179.KB890436_gene1448	1.1e-168	600.1	Bacteroidetes	aceK	GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.11.5	ko:K00906					ko00000,ko01000				Bacteria	4NIUY@976,COG4579@1,COG4579@2	NA|NA|NA	T	Isocitrate dehydrogenase kinase/phosphatase (AceK)
MAG.T21.45_00855	1515615.HQ41_09090	6.7e-45	186.8	Porphyromonadaceae	MA20_15755												Bacteria	230IQ@171551,2FT5C@200643,4NQGZ@976,COG3743@1,COG3743@2	NA|NA|NA	S	Domain of unknown function (DUF4332)
MAG.T21.45_00856	1121887.AUDK01000010_gene1416	5.9e-42	176.8	Flavobacterium	ble												Bacteria	1I2S1@117743,2NWXQ@237,4NQRN@976,COG0346@1,COG0346@2	NA|NA|NA	E	bleomycin resistance protein
MAG.T21.45_00857	1288963.ADIS_1567	9.3e-98	363.6	Cytophagia	ecm27			ko:K07301					ko00000,ko02000	2.A.19.5			Bacteria	47K1Z@768503,4NFBC@976,COG0530@1,COG0530@2	NA|NA|NA	P	Sodium/calcium exchanger protein
MAG.T21.45_00858	760192.Halhy_2210	7.9e-133	479.9	Sphingobacteriia													Bacteria	1IR19@117747,4NJK6@976,COG3828@1,COG3828@2	NA|NA|NA	S	Trehalose utilisation
MAG.T21.45_00859	760192.Halhy_2209	0.0	1741.9	Sphingobacteriia													Bacteria	1J0QI@117747,4NEQA@976,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2,COG2755@1,COG2755@2	NA|NA|NA	C	Cytochrome c
MAG.T21.45_00860	760192.Halhy_2208	1.4e-151	542.3	Sphingobacteriia													Bacteria	1IQK6@117747,4NKHA@976,COG1082@1,COG1082@2	NA|NA|NA	G	Xylose isomerase-like TIM barrel
MAG.T21.45_00861	760192.Halhy_2207	3.3e-214	750.7	Sphingobacteriia													Bacteria	1IQE9@117747,4NIIJ@976,COG4948@1,COG4948@2	NA|NA|NA	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
MAG.T21.45_00862	760192.Halhy_2206	7.8e-85	319.7	Sphingobacteriia													Bacteria	1ISA8@117747,4NN5T@976,COG0346@1,COG0346@2	NA|NA|NA	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MAG.T21.45_00863	760192.Halhy_2205	2.3e-112	412.1	Sphingobacteriia	serA		1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1IR1X@117747,4PKE3@976,COG1052@1,COG1052@2	NA|NA|NA	CH	D-isomer specific 2-hydroxyacid dehydrogenase
MAG.T21.45_00864	1123277.KB893183_gene111	6.3e-96	357.5	Cytophagia													Bacteria	47P0F@768503,4NHM4@976,COG1082@1,COG1082@2	NA|NA|NA	G	Xylose isomerase-like TIM barrel
MAG.T21.45_00865	760192.Halhy_1591	3.5e-45	188.3	Bacteria	yhcX			ko:K03824					ko00000,ko01000				Bacteria	COG3153@1,COG3153@2	NA|NA|NA	S	transferase activity, transferring acyl groups
MAG.T21.45_00866	331678.Cphamn1_1563	8.2e-26	124.0	Chlorobi													Bacteria	1FEZD@1090,COG1680@1,COG1680@2	NA|NA|NA	V	Fibrobacter succinogenes major domain (Fib_succ_major)
MAG.T21.45_00867	1120966.AUBU01000013_gene509	2.1e-82	313.5	Cytophagia													Bacteria	47MD8@768503,4NGS0@976,COG0457@1,COG0457@2	NA|NA|NA	K	Tetratricopeptide repeat
MAG.T21.45_00877	1121904.ARBP01000013_gene303	5.3e-106	391.3	Cytophagia													Bacteria	28KPG@1,2ZA7K@2,47MDA@768503,4NFWJ@976	NA|NA|NA		
MAG.T21.45_00878	1124780.ANNU01000003_gene1415	3.3e-39	168.7	Cytophagia													Bacteria	47PEW@768503,4NNIC@976,COG2755@1,COG2755@2	NA|NA|NA	E	PFAM GDSL-like Lipase Acylhydrolase
MAG.T21.45_00879	1239962.C943_00396	6e-204	716.8	Cytophagia													Bacteria	28KCX@1,2Z9ZQ@2,47JNB@768503,4NJ7S@976	NA|NA|NA		
MAG.T21.45_00880	1123248.KB893321_gene501	8.3e-162	577.4	Sphingobacteriia	btuB			ko:K02014,ko:K16092					ko00000,ko02000	1.B.14,1.B.14.3			Bacteria	1IQJR@117747,4NHH8@976,COG4206@1,COG4206@2	NA|NA|NA	H	Outer membrane cobalamin receptor protein
MAG.T21.45_00881	761193.Runsl_4666	1.1e-268	932.6	Cytophagia													Bacteria	47TF0@768503,4P11P@976,COG3292@1,COG3292@2	NA|NA|NA	T	Two component regulator propeller
MAG.T21.45_00882	504472.Slin_5085	0.0	1216.8	Cytophagia	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110		R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000				Bacteria	47KR2@768503,4NG30@976,COG0376@1,COG0376@2	NA|NA|NA	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MAG.T21.45_00883	760192.Halhy_1261	1.4e-52	212.6	Sphingobacteriia	msrC		1.8.4.14	ko:K08968	ko00270,map00270		R02025	RC00639	ko00000,ko00001,ko01000				Bacteria	1ISIR@117747,4NM6D@976,COG1956@1,COG1956@2	NA|NA|NA	T	GAF domain
MAG.T21.45_00884	700598.Niako_5459	2.7e-63	250.0	Sphingobacteriia													Bacteria	1IS3G@117747,4NFSH@976,COG4099@1,COG4099@2	NA|NA|NA	S	PFAM phospholipase Carboxylesterase
MAG.T21.45_00885	760192.Halhy_1115	2.8e-195	689.1	Sphingobacteriia				ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475			ko00000,ko00001,ko00002,ko02022				Bacteria	1IPII@117747,4PMP6@976,COG2197@1,COG2197@2,COG3292@1,COG3292@2	NA|NA|NA	KT	PFAM Y_Y_Y domain
MAG.T21.45_00886	760192.Halhy_1116	4.1e-235	821.2	Sphingobacteriia													Bacteria	1IPV2@117747,4NE34@976,COG5368@1,COG5368@2	NA|NA|NA	S	protein conserved in bacteria (DUF2329)
MAG.T21.45_00887	760192.Halhy_1117	0.0	1520.0	Bacteroidetes			3.2.1.4,5.2.1.8	ko:K01179,ko:K03768,ko:K08738	ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko03110	3.D.4.6	GH5,GH9		Bacteria	4NI6I@976,COG3291@1,COG3291@2	NA|NA|NA	G	Pkd domain containing protein
MAG.T21.45_00888	1122179.KB890419_gene54	6.3e-164	583.9	Bacteroidetes													Bacteria	4NE34@976,COG5368@1,COG5368@2	NA|NA|NA	S	protein conserved in bacteria
MAG.T21.45_00889	742767.HMPREF9456_02543	2.3e-240	838.6	Porphyromonadaceae	bglX		3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110		R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000		GH3		Bacteria	22WMM@171551,2FMCU@200643,4NE90@976,COG1472@1,COG1472@2	NA|NA|NA	G	PFAM Glycosyl hydrolase family 3 C terminal domain
MAG.T21.45_00890	760192.Halhy_1118	0.0	1208.4	Sphingobacteriia													Bacteria	1J0WH@117747,4P1Z5@976,COG1629@1,COG4771@2	NA|NA|NA	P	TonB dependent receptor
MAG.T21.45_00891	760192.Halhy_1119	2.8e-194	684.9	Bacteroidetes			1.14.14.47	ko:K00491,ko:K21572	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110		R11711,R11712,R11713	RC00177,RC00330,RC01044	ko00000,ko00001,ko01000,ko02000	8.A.46.1,8.A.46.3			Bacteria	4PKHQ@976,COG0702@1,COG0702@2	NA|NA|NA	GM	RagB SusD domain protein
MAG.T21.45_00892	929556.Solca_1966	0.0	1800.0	Sphingobacteriia	hsdR		3.1.21.3	ko:K01153					ko00000,ko01000,ko02048				Bacteria	1IR2G@117747,4NFJ8@976,COG0610@1,COG0610@2	NA|NA|NA	L	Subunit R is required for both nuclease and ATPase activities, but not for modification
MAG.T21.45_00893	1123008.KB905701_gene2232	2.6e-84	318.5	Porphyromonadaceae	satE			ko:K19134					ko00000,ko02048				Bacteria	22YDQ@171551,2FU0X@200643,4NJWC@976,COG5061@1,COG5061@2	NA|NA|NA	OU	Protein of unknown function (DUF3307)
MAG.T21.45_00894	1123008.KB905701_gene2233	1.7e-79	302.4	Porphyromonadaceae		GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944		ko:K07058,ko:K11709	ko02010,map02010	M00319			ko00000,ko00001,ko00002,ko02000	3.A.1.15			Bacteria	2327G@171551,2G10S@200643,4PMJZ@976,COG1846@1,COG1846@2	NA|NA|NA	K	SatD family (SatD)
MAG.T21.45_00895	376686.Fjoh_4394	1.7e-125	456.1	Flavobacterium			3.1.21.3	ko:K01154					ko00000,ko01000,ko02048				Bacteria	1I3U7@117743,2NX19@237,4NKMB@976,COG0732@1,COG0732@2	NA|NA|NA	V	Type I restriction modification DNA specificity domain
MAG.T21.45_00896	649349.Lbys_1357	8.2e-145	520.0	Cytophagia													Bacteria	47PMW@768503,4NEGN@976,COG3943@1,COG3943@2	NA|NA|NA	S	Virulence protein RhuM family
MAG.T21.45_00897	376686.Fjoh_4393	4.3e-254	883.6	Flavobacterium	hsdM		2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	1HYSD@117743,2NV8Q@237,4NG0E@976,COG0286@1,COG0286@2	NA|NA|NA	V	type I restriction-modification system
MAG.T21.45_00901	1392498.JQLH01000001_gene2596	2.7e-26	124.8	Flavobacteriia													Bacteria	1I41B@117743,2DNMS@1,32UJC@2,4NSPU@976	NA|NA|NA		
MAG.T21.45_00903	865938.Weevi_1860	3.8e-43	181.8	Flavobacteriia	yegX			ko:K07273					ko00000				Bacteria	1I18E@117743,4NKHF@976,COG3757@1,COG3757@2	NA|NA|NA	M	Glycoside Hydrolase
MAG.T21.45_00906	1270193.JARP01000001_gene2817	2.8e-44	185.3	Flavobacterium	yiiX												Bacteria	1IJ7X@117743,2NTDZ@237,4PKD4@976,COG3863@1,COG3863@2	NA|NA|NA	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MAG.T21.45_00907	317936.Nos7107_2133	7.9e-18	97.4	Nostocales													Bacteria	1GIYB@1117,1HT7U@1161,COG3409@1,COG3409@2	NA|NA|NA	M	Putative peptidoglycan binding domain
MAG.T21.45_00911	525897.Dbac_1252	2e-57	231.9	Bacteria				ko:K06921					ko00000				Bacteria	COG1672@1,COG1672@2	NA|NA|NA		
MAG.T21.45_00916	754477.Q7C_1566	7.4e-42	177.6	Bacteria			3.1.3.16,3.6.1.41	ko:K01525,ko:K07313	ko00230,map00230		R00125	RC00002	ko00000,ko00001,ko01000				Bacteria	COG0639@1,COG0639@2	NA|NA|NA	T	phosphoprotein phosphatase activity
MAG.T21.45_00918	290315.Clim_0481	1.7e-26	126.3	Chlorobi													Bacteria	1FF43@1090,COG4704@1,COG4704@2	NA|NA|NA	S	Fibrobacter succinogenes major domain (Fib_succ_major)
MAG.T21.45_00920	746697.Aeqsu_0191	1.2e-22	114.0	Flavobacteriia													Bacteria	1I1KI@117743,28S9Y@1,2ZEM4@2,4NN2V@976	NA|NA|NA		
MAG.T21.45_00922	344747.PM8797T_02349	4.3e-20	105.9	Planctomycetes													Bacteria	2J1FX@203682,COG4676@1,COG4676@2	NA|NA|NA	S	Protein conserved in bacteria
MAG.T21.45_00923	376686.Fjoh_4849	2.3e-32	146.7	Flavobacterium													Bacteria	1I7KI@117743,2NYDD@237,4P1V2@976,COG4192@1,COG4192@2	NA|NA|NA	T	Domain of unknown function (DUF4407)
MAG.T21.45_00926	331678.Cphamn1_1562	1e-35	157.5	Chlorobi													Bacteria	1FF57@1090,COG1680@1,COG1680@2	NA|NA|NA	V	Fibrobacter succinogenes major domain (Fib_succ_major)
MAG.T21.45_00928	938709.AUSH02000016_gene675	2.2e-27	129.4	Bacteroidetes				ko:K02477					ko00000,ko02022				Bacteria	4NFPV@976,COG3279@1,COG3279@2	NA|NA|NA	T	Response regulator of the LytR AlgR family
MAG.T21.45_00931	234267.Acid_1683	3.6e-21	109.8	Bacteria				ko:K03924					ko00000,ko01000				Bacteria	COG0714@1,COG0714@2	NA|NA|NA	KLT	Associated with various cellular activities
MAG.T21.45_00932	1123037.AUDE01000010_gene2391	3.4e-101	376.7	Flavobacteriia													Bacteria	1HX37@117743,4NFZB@976,COG2972@1,COG2972@2,COG3292@1,COG3292@2	NA|NA|NA	T	PFAM Signal transduction histidine kinase, internal region
MAG.T21.45_00933	1123037.AUDE01000010_gene2390	3e-43	182.2	Flavobacteriia				ko:K02477					ko00000,ko02022				Bacteria	1HXX5@117743,4NFPV@976,COG3279@1,COG3279@2	NA|NA|NA	T	response regulator
MAG.T21.45_00934	929562.Emtol_0435	1e-32	146.7	Bacteroidetes													Bacteria	2EJ52@1,31T38@2,4P2ZA@976	NA|NA|NA		
MAG.T21.45_00935	1121011.AUCB01000004_gene2867	4.6e-102	378.3	Arenibacter													Bacteria	1HXEI@117743,23HXA@178469,4NGZR@976,COG1680@1,COG1680@2	NA|NA|NA	V	Beta-lactamase
MAG.T21.45_00936	1121904.ARBP01000010_gene2357	3.1e-161	575.5	Cytophagia	serA	GO:0003674,GO:0003824,GO:0004617,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008219,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0012501,GO:0016053,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0070905,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.399,1.1.1.95,3.1.3.3	ko:K00058,ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582,R01513	RC00017,RC00031	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147			iYL1228.KPN_03348	Bacteria	47MQ2@768503,4NDVN@976,COG0111@1,COG0111@2,COG0560@1,COG0560@2	NA|NA|NA	EH	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MAG.T21.45_00937	760192.Halhy_0737	7.5e-238	829.7	Sphingobacteriia			1.14.14.47	ko:K00491,ko:K21572	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110		R11711,R11712,R11713	RC00177,RC00330,RC01044	ko00000,ko00001,ko01000,ko02000	8.A.46.1,8.A.46.3			Bacteria	1IQVG@117747,4NHVQ@976,COG0702@1,COG0702@2	NA|NA|NA	GM	RagB SusD domain protein
MAG.T21.45_00938	761193.Runsl_2484	0.0	1605.9	Cytophagia													Bacteria	47KGQ@768503,4NDXS@976,COG1629@1,COG1629@2	NA|NA|NA	P	PFAM TonB-dependent Receptor Plug
MAG.T21.45_00939	760192.Halhy_6474	2.1e-217	761.5	Sphingobacteriia													Bacteria	1IP4M@117747,4NDYI@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_00940	760192.Halhy_1950	1.4e-136	493.0	Sphingobacteriia				ko:K07133					ko00000				Bacteria	1IS38@117747,4NHQG@976,COG1373@1,COG1373@2	NA|NA|NA	S	Domain of unknown function (DUF4143)
MAG.T21.45_00942	760192.Halhy_3770	2.3e-139	501.9	Sphingobacteriia	accA	GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000			iAF1260.b0185,iBWG_1329.BWG_0177,iEC55989_1330.EC55989_0179,iECDH10B_1368.ECDH10B_0165,iECDH1ME8569_1439.ECDH1ME8569_0178,iECED1_1282.ECED1_0191,iECH74115_1262.ECH74115_0195,iECIAI1_1343.ECIAI1_0185,iECNA114_1301.ECNA114_0175,iECO111_1330.ECO111_0186,iECO26_1355.ECO26_0187,iECP_1309.ECP_0193,iECSE_1348.ECSE_0184,iECSF_1327.ECSF_0200,iECSP_1301.ECSP_0184,iECW_1372.ECW_m0181,iECs_1301.ECs0187,iEKO11_1354.EKO11_3733,iEcDH1_1363.EcDH1_3418,iEcE24377_1341.EcE24377A_0189,iEcHS_1320.EcHS_A0187,iG2583_1286.G2583_0188,iJN678.accA,iJN746.PP_1607,iJO1366.b0185,iJR904.b0185,iLF82_1304.LF82_0008,iNRG857_1313.NRG857_00945,iSDY_1059.SDY_0201,iSFV_1184.SFV_0168,iSF_1195.SF0175,iSFxv_1172.SFxv_0185,iS_1188.S0178,iUMNK88_1353.UMNK88_190,iWFL_1372.ECW_m0181,iY75_1357.Y75_RS00935,iZ_1308.Z0197	Bacteria	1IP0K@117747,4NEVU@976,COG0825@1,COG0825@2	NA|NA|NA	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MAG.T21.45_00943	1124780.ANNU01000003_gene1393	7.5e-07	60.8	Cytophagia													Bacteria	2ENX1@1,33GHZ@2,47WQI@768503,4NXFU@976	NA|NA|NA		
MAG.T21.45_00944	760192.Halhy_3772	1.1e-103	383.3	Sphingobacteriia	dapA		4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000				Bacteria	1INT7@117747,4NFP9@976,COG0329@1,COG0329@2	NA|NA|NA	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MAG.T21.45_00945	760192.Halhy_3050	2.5e-30	139.0	Bacteroidetes	trpF		5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000				Bacteria	4NMKY@976,COG0135@1,COG0135@2	NA|NA|NA	E	PFAM N-(5'phosphoribosyl)anthranilate (PRA) isomerase
MAG.T21.45_00946	1349822.NSB1T_12310	3.4e-61	241.5	Porphyromonadaceae	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030				ko00000,ko00001,ko01000,ko03032				Bacteria	22WJC@171551,2FMS7@200643,4NGVR@976,COG0164@1,COG0164@2	NA|NA|NA	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MAG.T21.45_00947	1122179.KB890425_gene3435	3.9e-13	81.3	Bacteroidetes													Bacteria	2EJD3@1,33D44@2,4NP3M@976	NA|NA|NA		
MAG.T21.45_00948	760192.Halhy_2909	3e-113	415.6	Sphingobacteriia	rodA			ko:K05837					ko00000,ko03036				Bacteria	1INPB@117747,4NDZD@976,COG0772@1,COG0772@2	NA|NA|NA	D	Belongs to the SEDS family
MAG.T21.45_00949	760192.Halhy_2910	6e-155	553.9	Sphingobacteriia	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773			R03789,R10209	RC00063	ko00000,ko01000,ko03016				Bacteria	1INNJ@117747,4NE15@976,COG0343@1,COG0343@2	NA|NA|NA	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MAG.T21.45_00950	760192.Halhy_3531	2.8e-114	418.7	Sphingobacteriia	lptG	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0033036,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1902494,GO:1902495,GO:1904949,GO:1990351		ko:K11720	ko02010,map02010	M00320			ko00000,ko00001,ko00002,ko02000	1.B.42.1		iSSON_1240.SSON_4447	Bacteria	1IPXP@117747,4NF8Y@976,COG0795@1,COG0795@2	NA|NA|NA	S	Permease, YjgP YjgQ family
MAG.T21.45_00951	1122179.KB890413_gene4750	3.7e-64	251.1	Sphingobacteriia	sigR_3			ko:K03088					ko00000,ko03021				Bacteria	1IPYA@117747,4NMM3@976,COG1595@1,COG1595@2	NA|NA|NA	K	Belongs to the sigma-70 factor family. ECF subfamily
MAG.T21.45_00952	1168289.AJKI01000011_gene485	2.5e-83	315.8	Marinilabiliaceae	mutY			ko:K03575	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	2FNMQ@200643,3XJ4J@558415,4NDZY@976,COG1194@1,COG1194@2	NA|NA|NA	L	NUDIX domain
MAG.T21.45_00953	760192.Halhy_2957	6.4e-35	153.7	Sphingobacteriia	ssb			ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440				ko00000,ko00001,ko03029,ko03032,ko03400				Bacteria	1ISJD@117747,4NQBK@976,COG0629@1,COG0629@2	NA|NA|NA	L	Single-stranded DNA-binding protein
MAG.T21.45_00954	1122176.KB903534_gene2154	4.4e-58	231.9	Sphingobacteriia	CP_0360												Bacteria	1IVGY@117747,4NDZ7@976,COG1253@1,COG1253@2	NA|NA|NA	S	Transporter associated domain
MAG.T21.45_00955	1122176.KB903535_gene1911	8.3e-36	157.1	Sphingobacteriia	gldD												Bacteria	1ISN4@117747,293VW@1,2ZRB2@2,4NMK7@976	NA|NA|NA	S	TIGRFAM gliding motility-associated lipoprotein GldD
MAG.T21.45_00956	1122176.KB903534_gene2132	5.2e-40	170.6	Bacteroidetes													Bacteria	4NQCK@976,COG4731@1,COG4731@2	NA|NA|NA	S	protein conserved in bacteria
MAG.T21.45_00958	760192.Halhy_2491	6.7e-98	363.6	Sphingobacteriia	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360		ko:K03553	ko03440,map03440	M00729			ko00000,ko00001,ko00002,ko03400				Bacteria	1INW2@117747,4NEXT@976,COG0468@1,COG0468@2	NA|NA|NA	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MAG.T21.45_00959	1392490.JHZX01000001_gene3536	2.6e-55	222.2	Flavobacteriia													Bacteria	1HZ6X@117743,4NFYN@976,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
MAG.T21.45_00961	1300143.CCAV010000008_gene3419	7.7e-10	72.4	Chryseobacterium													Bacteria	1I8J4@117743,3ZR6D@59732,4NK65@976,COG0642@1,COG2205@2,COG3292@1,COG3292@2	NA|NA|NA	T	PhoQ Sensor
MAG.T21.45_00962	1250232.JQNJ01000001_gene2110	5.7e-45	186.8	Flavobacteriia													Bacteria	1I2X2@117743,4NQ4W@976,COG4898@1,COG4898@2	NA|NA|NA	S	protein conserved in bacteria
MAG.T21.45_00963	1121897.AUGO01000007_gene386	3.2e-152	544.7	Flavobacterium	arsB		1.20.4.1	ko:K03325,ko:K03741					ko00000,ko01000,ko02000	2.A.59			Bacteria	1HWT1@117743,2NSVM@237,4NFG7@976,COG0798@1,COG0798@2	NA|NA|NA	P	arsenical-resistance protein
MAG.T21.45_00964	1500281.JQKZ01000005_gene3977	9.2e-75	286.6	Chryseobacterium	arsC		1.20.4.1	ko:K03741					ko00000,ko01000				Bacteria	1HYIW@117743,3ZR10@59732,4NE8C@976,COG0394@1,COG0394@2	NA|NA|NA	T	Protein tyrosine phosphatase
MAG.T21.45_00965	1137281.D778_02711	1.9e-19	102.1	Flavobacteriia			3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1HZVM@117743,4NGFJ@976,COG1349@1,COG1349@2,COG2865@1,COG2865@2	NA|NA|NA	K	Putative ATP-dependent DNA helicase recG C-terminal
MAG.T21.45_00966	1111730.ATTM01000006_gene2672	4.4e-38	163.7	Flavobacteriia													Bacteria	1IJZR@117743,4P4J4@976,COG3620@1,COG3620@2	NA|NA|NA	K	Helix-turn-helix domain
MAG.T21.45_00967	866536.Belba_1905	3e-43	181.0	Cytophagia		GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0045926,GO:0045927,GO:0046483,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0065007,GO:0070482,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360											Bacteria	47Q24@768503,4NPPR@976,COG4679@1,COG4679@2	NA|NA|NA	S	Phage derived protein Gp49-like (DUF891)
MAG.T21.45_00969	1034807.FBFL15_0029	1.8e-135	488.8	Flavobacterium													Bacteria	1HYQB@117743,2NU21@237,4NDYY@976,COG2207@1,COG2207@2	NA|NA|NA	K	Transcriptional regulator
MAG.T21.45_00970	1034807.FBFL15_0028	1.9e-54	218.8	Flavobacterium													Bacteria	1IDRG@117743,2A2MK@1,2NZ12@237,30QZX@2,4P5NJ@976	NA|NA|NA		
MAG.T21.45_00971	1086011.HJ01_02516	4.6e-130	470.7	Flavobacterium													Bacteria	1I0ZT@117743,2NT3J@237,4NHY6@976,COG4221@1,COG4221@2	NA|NA|NA	S	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAG.T21.45_00972	392500.Swoo_2968	2.9e-119	434.9	Gammaproteobacteria	hchA	GO:0003674,GO:0003700,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0006139,GO:0006259,GO:0006281,GO:0006355,GO:0006464,GO:0006517,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009100,GO:0009268,GO:0009438,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010447,GO:0010468,GO:0010556,GO:0016053,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019219,GO:0019222,GO:0019243,GO:0019249,GO:0019538,GO:0019752,GO:0030091,GO:0031323,GO:0031326,GO:0032787,GO:0033554,GO:0034641,GO:0036211,GO:0036524,GO:0036525,GO:0042180,GO:0042182,GO:0042221,GO:0042245,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046394,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051595,GO:0051596,GO:0051716,GO:0060255,GO:0061727,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901135,GO:1901360,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901654,GO:1901700,GO:1903506,GO:2000112,GO:2001141	3.5.1.124,4.2.1.130,5.3.1.6	ko:K01807,ko:K05523	ko00030,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00620,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056,R09796	RC00434,RC02658	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	1R41H@1224,1RR9T@1236,COG0693@1,COG0693@2	NA|NA|NA	S	Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE). Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA. Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair. Plays an important role in protecting cells from carbonyl stress
MAG.T21.45_00973	1168034.FH5T_18050	5.4e-196	690.6	Bacteroidetes													Bacteria	4NG08@976,COG3177@1,COG3177@2	NA|NA|NA	S	Fic/DOC family
MAG.T21.45_00974	929556.Solca_0938	1.4e-13	84.3	Sphingobacteriia													Bacteria	1IY2C@117747,4NQYR@976,COG4232@1,COG4232@2	NA|NA|NA	CO	Protein of unknown function, DUF255
MAG.T21.45_00977	997884.HMPREF1068_02274	1.5e-204	719.5	Bacteroidaceae				ko:K02316	ko03030,map03030				ko00000,ko00001,ko01000,ko03032				Bacteria	2G3FX@200643,4AKVS@815,4PKG1@976,COG0358@1,COG0358@2	NA|NA|NA	L	non supervised orthologous group
MAG.T21.45_00978	398720.MED217_15025	4.6e-08	63.9	Flavobacteriia				ko:K22299					ko00000,ko03000				Bacteria	1I5EM@117743,4NVJR@976,COG1396@1,COG1396@2	NA|NA|NA	K	Helix-turn-helix domain
MAG.T21.45_00979	1453500.AT05_03715	1e-114	420.6	Bacteria	rmuC			ko:K09760					ko00000				Bacteria	COG1322@1,COG1322@2	NA|NA|NA	S	DNA recombination
MAG.T21.45_00980	435591.BDI_2134	4.8e-113	414.8	Porphyromonadaceae			2.1.1.72	ko:K07316					ko00000,ko01000,ko02048				Bacteria	22Y1B@171551,2FNVJ@200643,4NFKE@976,COG2189@1,COG2189@2	NA|NA|NA	L	DNA methylase
MAG.T21.45_00981	487796.Flav2ADRAFT_0516	4.6e-114	417.9	Flavobacteriia													Bacteria	1HX1B@117743,4NDZF@976,COG4299@1,COG4299@2	NA|NA|NA	S	COGs COG4299 conserved
MAG.T21.45_00982	1517681.HW45_21100	2.2e-67	262.3	Vibrionales													Bacteria	1RF4B@1224,1SBWH@1236,1XST7@135623,COG4821@1,COG4821@2	NA|NA|NA	S	SIS domain
MAG.T21.45_00983	938709.AUSH02000073_gene1678	4.5e-54	218.4	Bacteroidetes													Bacteria	28NS9@1,2ZBRA@2,4NJGG@976	NA|NA|NA		
MAG.T21.45_00984	643867.Ftrac_0721	4e-97	361.7	Cytophagia			4.3.1.27	ko:K20757					ko00000,ko01000				Bacteria	47MJP@768503,4NF5K@976,COG3616@1,COG3616@2	NA|NA|NA	E	Putative serine dehydratase domain
MAG.T21.45_00985	760192.Halhy_0750	0.0	1081.2	Sphingobacteriia													Bacteria	1IQJ2@117747,4NFPC@976,COG3250@1,COG3250@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 2 family
MAG.T21.45_00987	1189612.A33Q_2987	1.2e-230	805.8	Cytophagia													Bacteria	47JYR@768503,4NHH7@976,COG3119@1,COG3119@2	NA|NA|NA	P	PFAM sulfatase
MAG.T21.45_00989	1048983.EL17_01890	2.7e-100	371.7	Cytophagia	crnA		3.5.2.10	ko:K01470	ko00330,map00330		R01884	RC00615	ko00000,ko00001,ko01000				Bacteria	47MQ8@768503,4NF2C@976,COG1402@1,COG1402@2	NA|NA|NA	S	Creatinine amidohydrolase
MAG.T21.45_00990	760192.Halhy_5224	8.6e-139	500.4	Sphingobacteriia													Bacteria	1J07W@117747,4P0TS@976,COG0507@1,COG0507@2	NA|NA|NA	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
MAG.T21.45_00991	1122176.KB903572_gene4842	7e-122	444.1	Sphingobacteriia	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360	2.1.1.176	ko:K03500					ko00000,ko01000,ko03009				Bacteria	1IPTE@117747,4NEV7@976,COG0144@1,COG0144@2	NA|NA|NA	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family
MAG.T21.45_00993	1313421.JHBV01000042_gene3336	2.5e-41	175.6	Sphingobacteriia													Bacteria	1ITPJ@117747,4NM5H@976,COG0224@1,COG0224@2	NA|NA|NA	C	WbqC-like protein family
MAG.T21.45_00994	760192.Halhy_6119	2.6e-47	195.7	Bacteria													Bacteria	COG0457@1,COG0457@2,COG2314@1,COG2314@2	NA|NA|NA	J	TM2 domain
MAG.T21.45_00995	477641.MODMU_3424	1.7e-70	272.7	Actinobacteria													Bacteria	2GKE1@201174,COG1028@1,COG1028@2	NA|NA|NA	IQ	Short-chain dehydrogenase reductase sdr
MAG.T21.45_00996	1296415.JACC01000025_gene1696	4.8e-25	121.7	Bacteroidetes													Bacteria	2DVBX@1,33V73@2,4P909@976	NA|NA|NA		
MAG.T21.45_00997	1123008.KB905693_gene1107	4.2e-143	514.6	Porphyromonadaceae	rarA			ko:K07478					ko00000				Bacteria	22W72@171551,2FNF4@200643,4NEV8@976,COG2256@1,COG2256@2	NA|NA|NA	L	ATPase (AAA
MAG.T21.45_00998	1122176.KB903541_gene220	4e-161	574.7	Sphingobacteriia	trkH	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662		ko:K03498,ko:K03499					ko00000,ko02000	2.A.38.1,2.A.38.4		iECDH1ME8569_1439.ECDH1ME8569_1308,iPC815.YPO3762,iSFV_1184.SFV_3651	Bacteria	1IUTC@117747,4NGMF@976,COG0168@1,COG0168@2	NA|NA|NA	P	Cation transport protein
MAG.T21.45_00999	1122179.KB890413_gene4873	1.2e-146	526.6	Sphingobacteriia	trkA			ko:K03499					ko00000,ko02000	2.A.38.1,2.A.38.4			Bacteria	1IWJ4@117747,4NE31@976,COG0569@1,COG0569@2	NA|NA|NA	P	TrkA-N domain
MAG.T21.45_01001	760192.Halhy_1433	2.3e-83	315.5	Sphingobacteriia			3.2.1.51	ko:K01206	ko00511,map00511				ko00000,ko00001,ko01000,ko04147		GH29		Bacteria	1IS5S@117747,4NGMS@976,COG2133@1,COG2133@2	NA|NA|NA	G	Domain of Unknown Function (DUF1080)
MAG.T21.45_01002	929562.Emtol_1644	1.1e-250	872.8	Cytophagia													Bacteria	47JK5@768503,4NFQ6@976,COG2091@1,COG2091@2	NA|NA|NA	H	lysine biosynthetic process via aminoadipic acid
MAG.T21.45_01003	1121904.ARBP01000010_gene2255	7.7e-55	220.7	Cytophagia													Bacteria	28HMY@1,2Z7WC@2,47Q27@768503,4NG8W@976	NA|NA|NA		
MAG.T21.45_01004	760192.Halhy_0833	1.5e-181	642.5	Sphingobacteriia	cca		2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018		R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019				Bacteria	1IPB1@117747,4NF1S@976,COG0617@1,COG0617@2	NA|NA|NA	J	tRNA nucleotidyltransferase
MAG.T21.45_01005	760192.Halhy_0834	4.3e-146	524.2	Sphingobacteriia	dus			ko:K05540					ko00000,ko01000,ko03016				Bacteria	1IP3N@117747,4NEN4@976,COG0042@1,COG0042@2	NA|NA|NA	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MAG.T21.45_01006	1122179.KB890416_gene2726	9.1e-144	516.9	Sphingobacteriia	nhaD												Bacteria	1IVHN@117747,4NGP4@976,COG1055@1,COG1055@2	NA|NA|NA	P	COG1055 Na H antiporter NhaD and related arsenite
MAG.T21.45_01008	760192.Halhy_0081	1.8e-81	310.1	Sphingobacteriia													Bacteria	1ISGZ@117747,28M10@1,2ZAFW@2,4NIF8@976	NA|NA|NA	S	Domain of unknown function (DUF4403)
MAG.T21.45_01009	760192.Halhy_6538	0.0	1536.2	Sphingobacteriia													Bacteria	1IUT7@117747,4NESU@976,COG4447@1,COG4447@2	NA|NA|NA	S	Sortilin, neurotensin receptor 3,
MAG.T21.45_01010	1122176.KB903619_gene5402	6.4e-10	69.3	Bacteria													Bacteria	2EK53@1,33DVI@2	NA|NA|NA		
MAG.T21.45_01011	1313301.AUGC01000001_gene1403	1.7e-153	549.3	Bacteroidetes	pyrC		3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000				Bacteria	4NE3T@976,COG0044@1,COG0044@2	NA|NA|NA	F	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides
MAG.T21.45_01012	1122176.KB903531_gene2812	6.1e-104	384.4	Sphingobacteriia	purK	GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000			iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477	Bacteria	1IQSA@117747,4NEGE@976,COG0026@1,COG0026@2	NA|NA|NA	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MAG.T21.45_01014	760192.Halhy_5634	7.4e-111	407.5	Sphingobacteriia													Bacteria	1IQNH@117747,4NG4W@976,COG5276@1,COG5276@2	NA|NA|NA	S	LVIVD repeat
MAG.T21.45_01015	760192.Halhy_0844	1.8e-169	602.4	Sphingobacteriia	cry		4.1.99.3	ko:K01669					ko00000,ko01000,ko03400				Bacteria	1IRAI@117747,4NDW0@976,COG0415@1,COG0415@2	NA|NA|NA	L	DNA photolyase
MAG.T21.45_01016	760192.Halhy_0195	3.6e-91	341.7	Sphingobacteriia	phuW												Bacteria	1INMM@117747,4NEQ4@976,COG3016@1,COG3016@2	NA|NA|NA	S	iron-regulated protein
MAG.T21.45_01017	760192.Halhy_0194	9.9e-30	136.3	Sphingobacteriia	aniA												Bacteria	1J09E@117747,4NEXP@976,COG2010@1,COG2010@2	NA|NA|NA	C	Cytochrome C oxidase, cbb3-type, subunit III
MAG.T21.45_01018	760192.Halhy_0193	5.6e-112	412.1	Bacteria			3.2.1.4,5.2.1.8	ko:K01179,ko:K03768,ko:K08738	ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko03110	3.D.4.6	GH5,GH9		Bacteria	COG3291@1,COG3291@2	NA|NA|NA	S	metallopeptidase activity
MAG.T21.45_01019	760192.Halhy_0274	4e-72	278.9	Sphingobacteriia	plsB		2.3.1.15	ko:K00630,ko:K00631,ko:K14598	ko00561,ko00564,ko00906,ko01100,ko01110,map00561,map00564,map00906,map01100,map01110	M00089	R00851,R07545,R07547,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1IYSE@117747,4NN7X@976,COG0204@1,COG0204@2	NA|NA|NA	I	Phosphate acyltransferases
MAG.T21.45_01020	468059.AUHA01000006_gene2839	2e-78	299.3	Sphingobacteriia	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110		R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016				Bacteria	1IPJH@117747,4NEAE@976,COG0324@1,COG0324@2	NA|NA|NA	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MAG.T21.45_01021	760192.Halhy_1747	3.2e-63	249.2	Sphingobacteriia	crtL		5.5.1.19	ko:K06443	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R03824,R04801,R05341,R06962,R07856	RC01004,RC01964	ko00000,ko00001,ko00002,ko01000				Bacteria	1IS7H@117747,4PM7G@976,COG0654@1,COG0654@2	NA|NA|NA	CH	Lycopene cyclase protein
MAG.T21.45_01022	760192.Halhy_1746	9.8e-39	167.5	Bacteroidetes	blh		1.13.11.63	ko:K21817					ko00000,ko01000				Bacteria	2A4Y1@1,30TJU@2,4NNHQ@976	NA|NA|NA	C	Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal
MAG.T21.45_01023	1122179.KB890432_gene4178	4.4e-108	397.5	Bacteroidetes													Bacteria	4NF9G@976,COG5524@1,COG5524@2	NA|NA|NA	S	Bacteriorhodopsin-like protein
MAG.T21.45_01024	1246484.D479_02072	1.1e-108	400.2	Halobacillus	nos	GO:0001505,GO:0003674,GO:0003824,GO:0004497,GO:0004517,GO:0006807,GO:0006809,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0017144,GO:0034641,GO:0042133,GO:0042136,GO:0044237,GO:0044249,GO:0044271,GO:0046209,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:1903409,GO:2001057	1.14.14.47	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110		R11711,R11712,R11713	RC00177,RC00330,RC01044	ko00000,ko00001,ko01000				Bacteria	1TRDM@1239,3NEM2@45667,4HAR0@91061,COG4362@1,COG4362@2	NA|NA|NA	EP	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MAG.T21.45_01025	406818.XBJ1_2507	1.2e-36	159.5	Gammaproteobacteria	menI	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0034641,GO:0042180,GO:0042181,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0061522,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000				Bacteria	1RGVP@1224,1S5WY@1236,COG2050@1,COG2050@2	NA|NA|NA	Q	Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA)
MAG.T21.45_01026	1122179.KB890415_gene2035	4e-129	469.2	Sphingobacteriia													Bacteria	1IYS6@117747,4NDUD@976,COG5276@1,COG5276@2	NA|NA|NA	S	cellulase activity
MAG.T21.45_01027	760192.Halhy_5601	1.8e-132	479.9	Bacteroidetes			3.4.21.50	ko:K01337,ko:K07004					ko00000,ko01000,ko01002				Bacteria	4NG2K@976,COG3210@1,COG3210@2,COG3591@1,COG3591@2	NA|NA|NA	E	Pkd domain containing protein
MAG.T21.45_01029	760192.Halhy_0452	6.7e-207	727.2	Sphingobacteriia	pulA		3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110		R02111		ko00000,ko00001,ko01000		CBM48,GH13		Bacteria	1IV4P@117747,4NIH2@976,COG1523@1,COG1523@2	NA|NA|NA	G	COGs COG1523 Type II secretory pathway pullulanase PulA and related glycosidase
MAG.T21.45_01030	1121904.ARBP01000080_gene6043	6.1e-299	1033.5	Cytophagia	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000			iJN678.ppc	Bacteria	47NYT@768503,4NFC0@976,COG2352@1,COG2352@2	NA|NA|NA	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MAG.T21.45_01031	760192.Halhy_0661	4.5e-142	511.1	Sphingobacteriia	pgk	GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1IPGS@117747,4NFW2@976,COG0126@1,COG0126@2	NA|NA|NA	G	Belongs to the phosphoglycerate kinase family
MAG.T21.45_01032	760192.Halhy_0662	9.8e-143	513.1	Sphingobacteriia	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147				Bacteria	1IQAX@117747,4NEMF@976,COG0057@1,COG0057@2	NA|NA|NA	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MAG.T21.45_01035	1367491.BN865_09650	7.5e-21	106.3	Epsilonproteobacteria				ko:K09981					ko00000				Bacteria	1N6ZY@1224,2YQ7I@29547,42VNA@68525,COG3809@1,COG3809@2	NA|NA|NA	S	Transcription factor zinc-finger
MAG.T21.45_01036	485917.Phep_2883	3.3e-208	731.1	Sphingobacteriia													Bacteria	1IWEU@117747,4NH13@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_01037	929562.Emtol_3843	2.7e-57	228.8	Cytophagia	yfkO												Bacteria	47Q2S@768503,4NEA5@976,COG0778@1,COG0778@2	NA|NA|NA	C	Nitroreductase family
MAG.T21.45_01038	760192.Halhy_5888	4e-155	554.3	Sphingobacteriia	trxB2		1.18.1.2,1.19.1.1,1.8.1.9	ko:K00384,ko:K21567	ko00450,map00450		R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000				Bacteria	1IQVX@117747,4NEQM@976,COG0492@1,COG0492@2	NA|NA|NA	C	Ferredoxin--NADP reductase
MAG.T21.45_01039	760192.Halhy_5341	0.0	1078.2	Sphingobacteriia	zinT			ko:K09815,ko:K20276	ko02010,ko02024,map02010,map02024	M00242			ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5			Bacteria	1IQYI@117747,4PKBQ@976,COG3209@1,COG3209@2,COG3391@1,COG3391@2,COG4932@1,COG4932@2	NA|NA|NA	M	SprB repeat
MAG.T21.45_01040	760192.Halhy_5342	2.6e-120	438.7	Sphingobacteriia			1.11.1.5	ko:K00428					ko00000,ko01000				Bacteria	1INRI@117747,4NE4P@976,COG1858@1,COG1858@2	NA|NA|NA	C	cytochrome C peroxidase
MAG.T21.45_01041	760192.Halhy_5343	5.9e-83	314.3	Bacteroidetes			1.11.1.5	ko:K00428					ko00000,ko01000				Bacteria	4NE4P@976,COG1858@1,COG1858@2	NA|NA|NA	C	cytochrome C peroxidase
MAG.T21.45_01042	604331.AUHY01000043_gene2776	1.1e-08	67.4	Deinococcus-Thermus													Bacteria	1WMK5@1297,2DQAI@1,335NH@2	NA|NA|NA		
MAG.T21.45_01044	760192.Halhy_5346	6.8e-105	387.1	Sphingobacteriia	dnaQ		2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1IPA8@117747,4NE82@976,COG0847@1,COG0847@2	NA|NA|NA	L	DNA polymerase III
MAG.T21.45_01045	760192.Halhy_5347	3.5e-87	328.6	Sphingobacteriia	apbE	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564	1.8.1.2,2.7.1.180	ko:K00380,ko:K03734	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000				Bacteria	1INSG@117747,4NGEK@976,COG1477@1,COG1477@2	NA|NA|NA	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MAG.T21.45_01046	1313421.JHBV01000030_gene2255	2.9e-29	134.8	Sphingobacteriia				ko:K15977					ko00000				Bacteria	1IU1V@117747,4NSBJ@976,COG2259@1,COG2259@2	NA|NA|NA	S	DoxX
MAG.T21.45_01047	760192.Halhy_5357	3.4e-88	331.6	Sphingobacteriia	ygdQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944											Bacteria	1IQQC@117747,4NFFD@976,COG0861@1,COG0861@2	NA|NA|NA	P	Membrane protein TerC, possibly involved in tellurium resistance
MAG.T21.45_01048	760192.Halhy_5360	4.4e-89	334.3	Sphingobacteriia	trmD	GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228,4.6.1.12	ko:K00554,ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R00597,R05637	RC00002,RC00003,RC00334,RC01440	ko00000,ko00001,ko00002,ko01000,ko03016				Bacteria	1IQ54@117747,4NF2Q@976,COG0336@1,COG0336@2	NA|NA|NA	J	Belongs to the RNA methyltransferase TrmD family
MAG.T21.45_01049	760192.Halhy_5361	6.4e-69	267.3	Sphingobacteriia	fklB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005527,GO:0005528,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042597,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:0140096,GO:1901363,GO:1901564	5.2.1.8	ko:K01802,ko:K03772,ko:K03773					ko00000,ko01000,ko03110				Bacteria	1IT0Z@117747,4NDW4@976,COG0545@1,COG0545@2	NA|NA|NA	O	PFAM FKBP-type peptidyl-prolyl cis-trans isomerase
MAG.T21.45_01050	760192.Halhy_5366	2.9e-67	261.5	Sphingobacteriia	ubiX	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000				Bacteria	1INXX@117747,4NIBD@976,COG0163@1,COG0163@2	NA|NA|NA	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MAG.T21.45_01051	760192.Halhy_5367	8.4e-49	200.3	Sphingobacteriia													Bacteria	1ITRS@117747,4PKPW@976,COG1331@1,COG1331@2	NA|NA|NA	O	COG1331 Highly conserved protein containing a thioredoxin domain
MAG.T21.45_01052	760192.Halhy_1080	9.1e-48	197.2	Sphingobacteriia	spoU		2.1.1.170,2.1.1.185,2.1.1.34	ko:K00556,ko:K03218,ko:K03437,ko:K03501					ko00000,ko01000,ko03009,ko03016,ko03036				Bacteria	1IQKS@117747,4NG1U@976,COG0566@1,COG0566@2	NA|NA|NA	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MAG.T21.45_01053	760192.Halhy_1081	7.7e-149	534.6	Sphingobacteriia				ko:K07277					ko00000,ko02000,ko03029	1.B.33			Bacteria	1IPP9@117747,4NE80@976,COG4775@1,COG4775@2	NA|NA|NA	M	Outer membrane protein protective antigen OMA87
MAG.T21.45_01054	1122176.KB903538_gene1481	2e-40	173.7	Sphingobacteriia				ko:K01999	ko02010,ko02024,map02010,map02024	M00237			ko00000,ko00001,ko00002,ko02000	3.A.1.4			Bacteria	1ISIQ@117747,4PMPE@976,COG0683@1,COG0683@2	NA|NA|NA	E	leucine binding
MAG.T21.45_01055	1122179.KB890417_gene3317	3.4e-206	724.5	Sphingobacteriia	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.3.1.128,6.3.5.2	ko:K01951,ko:K03790	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002,ko03009			iLJ478.TM1820	Bacteria	1INX4@117747,4NESX@976,COG0519@1,COG0519@2	NA|NA|NA	F	Catalyzes the synthesis of GMP from XMP
MAG.T21.45_01056	760192.Halhy_6531	6.8e-93	347.4	Sphingobacteriia	nusB			ko:K03625					ko00000,ko03009,ko03021				Bacteria	1ISHE@117747,4NDVR@976,COG0781@1,COG0781@2	NA|NA|NA	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MAG.T21.45_01057	1122176.KB903609_gene5208	4.3e-126	458.4	Sphingobacteriia													Bacteria	1IPIJ@117747,4NGNF@976,COG2259@1,COG2259@2	NA|NA|NA	O	DoxX family
MAG.T21.45_01058	1313421.JHBV01000030_gene2134	3.9e-56	224.6	Sphingobacteriia													Bacteria	1IRWB@117747,28HFG@1,2Z7RJ@2,4NFNY@976	NA|NA|NA	S	Domain of Unknown Function (DUF1599)
MAG.T21.45_01059	1349785.BAUG01000045_gene2258	7.8e-35	154.5	Flavobacteriia													Bacteria	1HWX9@117743,4NGWA@976,COG0697@1,COG0697@2	NA|NA|NA	EG	EamA-like transporter family
MAG.T21.45_01060	760192.Halhy_5604	2.6e-51	208.8	Sphingobacteriia	yigZ		2.1.1.45,3.4.13.9	ko:K00560,ko:K01271	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	1IQV2@117747,4NF0D@976,COG1739@1,COG1739@2	NA|NA|NA	S	PFAM Uncharacterised protein family UPF0029, Impact, N-terminal
MAG.T21.45_01061	760192.Halhy_6308	7.2e-31	141.0	Bacteroidetes													Bacteria	2DTID@1,33KGU@2,4NZE6@976	NA|NA|NA		
MAG.T21.45_01062	760192.Halhy_0045	2.1e-232	812.4	Sphingobacteriia	malQ		2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100		R05196	RC00049	ko00000,ko00001,ko01000		GH77		Bacteria	1IPKN@117747,4NF7Z@976,COG1640@1,COG1640@2	NA|NA|NA	G	PFAM Glycoside hydrolase, family 77
MAG.T21.45_01064	760192.Halhy_2522	5.4e-13	79.7	Sphingobacteriia	rpsU	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02970	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IU0K@117747,4NUPV@976,COG0828@1,COG0828@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bS21 family
MAG.T21.45_01065	1123037.AUDE01000016_gene252	1.6e-165	589.7	Flavobacteriia	nuoL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00341,ko:K12137	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1			Bacteria	1HWXX@117743,4NEBM@976,COG1009@1,COG1009@2	NA|NA|NA	CP	NADH ubiquinone oxidoreductase subunit
MAG.T21.45_01066	1123037.AUDE01000016_gene253	2.4e-294	1018.1	Flavobacteriia				ko:K09822					ko00000				Bacteria	1I0SZ@117743,4NECE@976,COG3002@1,COG3002@2	NA|NA|NA	S	Belongs to the UPF0753 family
MAG.T21.45_01067	1121889.AUDM01000001_gene159	6.3e-48	197.2	Flavobacterium													Bacteria	1HYXB@117743,2NV0A@237,4NE9G@976,COG0659@1,COG0659@2	NA|NA|NA	P	Sulfate permease family
MAG.T21.45_01068	938709.AUSH02000020_gene1986	8.5e-63	248.4	Bacteroidetes													Bacteria	4NHDQ@976,COG3656@1,COG3656@2,COG5295@1,COG5295@2	NA|NA|NA	UW	fibronectin type III domain protein
MAG.T21.45_01069	694427.Palpr_2226	1e-66	261.2	Porphyromonadaceae				ko:K21571					ko00000				Bacteria	22Y91@171551,2FTSH@200643,4NHDQ@976,COG3656@1,COG3656@2	NA|NA|NA	S	Fibronectin type 3 domain
MAG.T21.45_01070	391598.FBBAL38_11469	9.9e-50	204.5	Flavobacteriia													Bacteria	1I4NQ@117743,4NTMP@976,COG4704@1,COG4704@2,COG5295@1,COG5295@2	NA|NA|NA	UW	Hep Hag repeat protein
MAG.T21.45_01071	504487.JCM19302_1650	5.1e-62	244.6	Flavobacteriia													Bacteria	1I518@117743,29X24@1,30IQJ@2,4P9MS@976	NA|NA|NA	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system
MAG.T21.45_01072	504487.JCM19302_1651	3.3e-17	94.0	Flavobacteriia													Bacteria	1I76T@117743,2EB0Y@1,3351U@2,4NX8Q@976	NA|NA|NA		
MAG.T21.45_01075	760192.Halhy_2915	7.1e-163	580.5	Sphingobacteriia	mnmE	GO:0003674,GO:0005488,GO:0005515,GO:0042802		ko:K03650			R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016				Bacteria	1IPFD@117747,4NECT@976,COG0486@1,COG0486@2	NA|NA|NA	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MAG.T21.45_01076	760192.Halhy_4130	6.5e-160	570.5	Sphingobacteriia			3.4.13.19	ko:K01273					ko00000,ko00537,ko01000,ko01002,ko04147				Bacteria	1IQAA@117747,4NEBG@976,COG2355@1,COG2355@2	NA|NA|NA	E	Membrane dipeptidase (Peptidase family M19)
MAG.T21.45_01077	760192.Halhy_3854	2.8e-36	158.7	Bacteroidetes													Bacteria	4NYY3@976,COG3637@1,COG3637@2	NA|NA|NA	M	Outer membrane protein beta-barrel domain
MAG.T21.45_01078	760192.Halhy_3853	3.5e-20	104.4	Sphingobacteriia													Bacteria	1ITUK@117747,2E4YQ@1,32ZSH@2,4NVKX@976	NA|NA|NA		
MAG.T21.45_01079	760192.Halhy_3852	3e-70	271.9	Sphingobacteriia	phnP		2.3.1.181,3.1.4.55	ko:K03801,ko:K06167	ko00440,ko00785,ko01100,map00440,map00785,map01100		R07766,R07769,R10205	RC00039,RC00296,RC00992,RC02867	ko00000,ko00001,ko01000				Bacteria	1INS0@117747,4NDWB@976,COG1235@1,COG1235@2	NA|NA|NA	S	of the beta-lactamase superfamily I
MAG.T21.45_01080	1122176.KB903546_gene1018	2.4e-11	75.9	Bacteria	dacA1		3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100				ko00000,ko00001,ko01000,ko01002,ko01011				Bacteria	COG3087@1,COG3087@2	NA|NA|NA	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MAG.T21.45_01081	760192.Halhy_2678	1.1e-139	503.1	Sphingobacteriia				ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111				ko00000,ko00001,ko03000				Bacteria	1INRY@117747,4NFB1@976,COG0664@1,COG0664@2,COG0745@1,COG0745@2	NA|NA|NA	T	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase
MAG.T21.45_01082	760192.Halhy_2679	1.2e-119	437.2	Sphingobacteriia			3.1.4.52	ko:K03406,ko:K13243	ko02020,ko02030,map02020,map02030		R08991	RC00296	ko00000,ko00001,ko01000,ko02035				Bacteria	1IPHZ@117747,4NG0Y@976,COG0642@1,COG2205@2,COG3829@1,COG3829@2	NA|NA|NA	T	PhoQ Sensor
MAG.T21.45_01083	935948.KE386494_gene398	3e-07	61.2	Thermoanaerobacterales													Bacteria	1VEYC@1239,24QMF@186801,42H6Q@68295,COG0526@1,COG0526@2	NA|NA|NA	CO	redox-active disulfide protein 2
MAG.T21.45_01084	1121904.ARBP01000028_gene1638	1.1e-24	120.6	Cytophagia													Bacteria	47XGN@768503,4NHXF@976,COG0589@1,COG0589@2	NA|NA|NA	T	Universal stress protein family
MAG.T21.45_01085	1123276.KB893268_gene4848	2.3e-84	318.9	Cytophagia													Bacteria	47NJC@768503,4NHXV@976,COG3568@1,COG3568@2	NA|NA|NA	S	PFAM Endonuclease Exonuclease phosphatase
MAG.T21.45_01086	760192.Halhy_2800	4.2e-73	281.6	Sphingobacteriia				ko:K09973					ko00000				Bacteria	1ITG6@117747,4NN4U@976,COG3735@1,COG3735@2	NA|NA|NA	S	TraB family
MAG.T21.45_01087	760192.Halhy_2799	2.8e-30	139.4	Sphingobacteriia													Bacteria	1IWJW@117747,4NQY3@976,COG0457@1,COG0457@2	NA|NA|NA	S	Protein of unknown function (DUF3137)
MAG.T21.45_01088	760192.Halhy_3959	4.4e-58	231.1	Bacteroidetes													Bacteria	2E26H@1,32XCY@2,4P5BB@976	NA|NA|NA		
MAG.T21.45_01089	1121931.AUHG01000010_gene559	1.8e-53	216.1	Flavobacteriia	comF												Bacteria	1I22C@117743,4NNI1@976,COG1040@1,COG1040@2	NA|NA|NA	S	amidophosphoribosyl-transferase
MAG.T21.45_01090	760192.Halhy_2732	1.8e-98	365.5	Sphingobacteriia	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100		R00158	RC00002	ko00000,ko00001,ko01000			iSB619.SA_RS06240	Bacteria	1IPN7@117747,4NE8Z@976,COG0528@1,COG0528@2	NA|NA|NA	F	Catalyzes the reversible phosphorylation of UMP to UDP
MAG.T21.45_01091	760192.Halhy_2731	3.3e-99	368.2	Sphingobacteriia	tsf	GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065		ko:K02357					ko00000,ko03012,ko03029				Bacteria	1IP5Z@117747,4NF03@976,COG0264@1,COG0264@2	NA|NA|NA	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MAG.T21.45_01092	760192.Halhy_2730	1.5e-108	399.1	Sphingobacteriia	rpsB	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02967	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IQSP@117747,4NER0@976,COG0052@1,COG0052@2	NA|NA|NA	J	Belongs to the universal ribosomal protein uS2 family
MAG.T21.45_01093	760192.Halhy_2729	6.9e-52	209.9	Sphingobacteriia	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02996	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1ISJG@117747,4NNN1@976,COG0103@1,COG0103@2	NA|NA|NA	J	Belongs to the universal ribosomal protein uS9 family
MAG.T21.45_01094	760192.Halhy_2728	2.3e-51	208.4	Sphingobacteriia	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113		ko:K02871	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IS32@117747,4NNGA@976,COG0102@1,COG0102@2	NA|NA|NA	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MAG.T21.45_01095	1122176.KB903542_gene376	1.6e-111	409.5	Sphingobacteriia	yahG												Bacteria	1IYN1@117747,4NJPE@976,COG1304@1,COG1304@2	NA|NA|NA	C	COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid
MAG.T21.45_01096	760192.Halhy_4185	3.8e-142	511.5	Bacteroidetes	mvaA		1.1.1.34,1.1.1.88,2.3.1.9	ko:K00021,ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,ko04152,ko04976,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020,map04152,map04976	M00088,M00095,M00373,M00374,M00375	R00238,R01177,R02081,R02082	RC00004,RC00326,RC00644	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	4NGNG@976,COG1257@1,COG1257@2	NA|NA|NA	I	Belongs to the HMG-CoA reductase family
MAG.T21.45_01097	1042376.AFPK01000028_gene2048	9.5e-63	247.3	unclassified Flavobacteriaceae	mvaK2		2.7.1.36,2.7.4.2	ko:K00869,ko:K00938	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245,R03245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1HY6C@117743,406B7@61432,4NEXC@976,COG1577@1,COG1577@2	NA|NA|NA	I	GHMP Kinase
MAG.T21.45_01098	760192.Halhy_4183	1.5e-58	233.0	Sphingobacteriia	poxF		1.17.1.1	ko:K00523	ko00520,map00520		R03391,R03392	RC00230	ko00000,ko00001,ko01000				Bacteria	1IXDV@117747,4PN6Y@976,COG1018@1,COG1018@2	NA|NA|NA	C	Oxidoreductase FAD-binding domain
MAG.T21.45_01099	1122176.KB903546_gene979	5.3e-78	297.4	Sphingobacteriia	nifU												Bacteria	1IQ4T@117747,4NG0Q@976,COG0694@1,COG0694@2	NA|NA|NA	O	PFAM Scaffold protein Nfu NifU N terminal
MAG.T21.45_01100	760192.Halhy_2039	4.4e-158	565.5	Bacteroidetes			3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100		R01206,R02334	RC00467	ko00000,ko00001,ko01000		GH18		Bacteria	4NHTI@976,COG2931@1,COG2931@2,COG3227@1,COG3227@2,COG3292@1,COG3292@2	NA|NA|NA	T	zinc metalloprotease
MAG.T21.45_01101	760192.Halhy_5744	2e-180	639.0	Sphingobacteriia	wprA												Bacteria	1INME@117747,4NF1M@976,COG1404@1,COG1404@2	NA|NA|NA	O	Peptidase S8 and S53 subtilisin kexin sedolisin
MAG.T21.45_01102	1122179.KB890441_gene1069	1.5e-151	543.5	Sphingobacteriia													Bacteria	1IR9W@117747,4NGZV@976,COG3291@1,COG3291@2	NA|NA|NA	U	PFAM PKD domain
MAG.T21.45_01103	760192.Halhy_5743	3.5e-37	162.2	Sphingobacteriia													Bacteria	1IXCE@117747,4NG1S@976,COG4122@1,COG4122@2	NA|NA|NA	S	Methyltransferase domain
MAG.T21.45_01104	1231626.CAHE_0179	1.3e-37	163.7	Cytophagia													Bacteria	47K3M@768503,4NJT2@976,COG5464@1,COG5464@2	NA|NA|NA	S	PD-(D/E)XK nuclease family transposase
MAG.T21.45_01105	743722.Sph21_1453	2e-289	1001.5	Sphingobacteriia	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614				ko00000,ko00001,ko01000,ko01002				Bacteria	1IRD1@117747,4NFJS@976,COG1505@1,COG1505@2	NA|NA|NA	E	Prolyl endopeptidase
MAG.T21.45_01106	1122176.KB903540_gene11	2.4e-164	585.1	Sphingobacteriia													Bacteria	1IREZ@117747,4NFMS@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase
MAG.T21.45_01107	1122179.KB890414_gene1769	2.3e-59	235.7	Sphingobacteriia			3.2.1.51	ko:K01206	ko00511,map00511				ko00000,ko00001,ko01000,ko04147		GH29		Bacteria	1IS4K@117747,4PKJE@976,COG2133@1,COG2133@2	NA|NA|NA	G	Domain of Unknown Function (DUF1080)
MAG.T21.45_01108	760192.Halhy_2762	2e-72	279.3	Sphingobacteriia													Bacteria	1J0X2@117747,4PP1J@976,COG4319@1,COG4319@2	NA|NA|NA	S	SnoaL-like domain
MAG.T21.45_01109	760192.Halhy_3280	1.5e-85	323.2	Sphingobacteriia	pla	GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704,GO:1901575											Bacteria	1IT00@117747,4NK38@976,COG2267@1,COG2267@2	NA|NA|NA	I	Protein of unknown function (DUF3089)
MAG.T21.45_01110	760192.Halhy_3279	2.5e-124	452.2	Sphingobacteriia	vicK		2.1.1.80,2.7.13.3,3.1.1.61	ko:K07709,ko:K13924	ko02020,ko02030,map02020,map02030	M00499,M00506			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035				Bacteria	1J0MH@117747,4NEMP@976,COG4191@1,COG4191@2	NA|NA|NA	T	His Kinase A (phosphoacceptor) domain
MAG.T21.45_01111	760192.Halhy_2453	7.7e-127	460.7	Sphingobacteriia	natB			ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1IR1T@117747,4NFSZ@976,COG1668@1,COG1668@2	NA|NA|NA	CP	ABC-type Na efflux pump, permease component
MAG.T21.45_01112	1122605.KB893649_gene3749	3e-146	525.4	Sphingobacteriia													Bacteria	1IRRQ@117747,4NEQ5@976,COG3119@1,COG3119@2	NA|NA|NA	P	PFAM sulfatase
MAG.T21.45_01113	1122605.KB893649_gene3752	6.1e-165	588.2	Bacteroidetes	yteR												Bacteria	4NGSJ@976,COG4225@1,COG4225@2	NA|NA|NA	E	Glycosyl Hydrolase Family 88
MAG.T21.45_01114	760192.Halhy_2452	5.7e-105	387.5	Sphingobacteriia	natA			ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1IQ0E@117747,4NEJE@976,COG4152@1,COG4152@2	NA|NA|NA	S	ABC transporter
MAG.T21.45_01115	760192.Halhy_3283	2.7e-207	728.4	Sphingobacteriia	MdlB			ko:K06147,ko:K18890	ko02010,map02010	M00707			ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21			Bacteria	1IQFU@117747,4NEAG@976,COG1132@1,COG1132@2	NA|NA|NA	V	ABC transporter
MAG.T21.45_01116	760192.Halhy_3802	2.8e-14	85.1	Sphingobacteriia			2.3.1.1	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000				Bacteria	1IZEW@117747,4PJYU@976,COG0454@1,COG0456@2	NA|NA|NA	K	acetyltransferase
MAG.T21.45_01117	760192.Halhy_3803	2.5e-133	482.6	Bacteria	bpr	GO:0005575,GO:0005576		ko:K13276					ko00000,ko01000,ko01002,ko03110				Bacteria	COG1404@1,COG1404@2	NA|NA|NA	O	Belongs to the peptidase S8 family
MAG.T21.45_01118	760192.Halhy_3485	7.9e-143	513.5	Sphingobacteriia	yceA			ko:K07146					ko00000				Bacteria	1IT0S@117747,4NEG6@976,COG1054@1,COG1054@2	NA|NA|NA	S	Belongs to the UPF0176 family
MAG.T21.45_01119	1122176.KB903544_gene727	7.2e-20	104.4	Sphingobacteriia													Bacteria	1ITXU@117747,4NUNS@976,COG0791@1,COG0791@2	NA|NA|NA	M	COGs COG0791 Cell wall-associated hydrolase (invasion-associated protein)
MAG.T21.45_01120	760192.Halhy_2375	6.6e-163	580.5	Sphingobacteriia													Bacteria	1IWW4@117747,4NE5U@976,COG1228@1,COG1228@2	NA|NA|NA	Q	Amidohydrolase family
MAG.T21.45_01121	760192.Halhy_2376	5.9e-178	630.6	Sphingobacteriia													Bacteria	1IVYR@117747,4NF27@976,COG1228@1,COG1228@2	NA|NA|NA	Q	Amidohydrolase family
MAG.T21.45_01122	760192.Halhy_2377	1.1e-131	477.2	Sphingobacteriia													Bacteria	1IWA0@117747,4NHGA@976,COG1228@1,COG1228@2	NA|NA|NA	Q	Amidohydrolase family
MAG.T21.45_01123	1122176.KB903571_gene4786	1.6e-133	483.4	Sphingobacteriia													Bacteria	1IZUU@117747,4NMZG@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.45_01124	760192.Halhy_2378	5.3e-301	1040.4	Sphingobacteriia	nagA		3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000				Bacteria	1IP6G@117747,4NET8@976,COG1472@1,COG1472@2,COG1680@1,COG1680@2	NA|NA|NA	G	PFAM glycoside hydrolase family 3
MAG.T21.45_01125	880070.Cycma_4634	2.9e-234	818.9	Cytophagia				ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6			Bacteria	47MFW@768503,4NH6B@976,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2	NA|NA|NA	C	PFAM PBS lyase
MAG.T21.45_01126	755732.Fluta_0734	3.2e-13	82.0	Cryomorphaceae	yisX												Bacteria	1I2VH@117743,2PAZV@246874,4NQ3B@976,COG1357@1,COG1357@2	NA|NA|NA	S	PFAM Pentapeptide
MAG.T21.45_01127	1122176.KB903539_gene1387	3.7e-89	334.7	Sphingobacteriia	fmt2		3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240		R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000				Bacteria	1IQ3T@117747,4NF20@976,COG1611@1,COG1611@2	NA|NA|NA	S	Belongs to the LOG family
MAG.T21.45_01128	1313421.JHBV01000023_gene5162	2.4e-149	535.4	Sphingobacteriia	ntrX												Bacteria	1IPCA@117747,4NE89@976,COG2204@1,COG2204@2	NA|NA|NA	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
MAG.T21.45_01129	760192.Halhy_1481	6.8e-130	470.7	Sphingobacteriia				ko:K01436,ko:K12941					ko00000,ko01000,ko01002				Bacteria	1INTB@117747,4NGBI@976,COG1473@1,COG1473@2	NA|NA|NA	S	amidohydrolase
MAG.T21.45_01130	1122176.KB903547_gene1127	1.3e-140	506.5	Sphingobacteriia	sdcS			ko:K14445					ko00000,ko02000	2.A.47.1			Bacteria	1IVXF@117747,4NFDK@976,COG0471@1,COG0471@2	NA|NA|NA	P	Sodium:sulfate symporter transmembrane region
MAG.T21.45_01131	1121904.ARBP01000009_gene4389	1.2e-148	533.1	Cytophagia													Bacteria	47JAV@768503,4NF9W@976,COG0671@1,COG0671@2	NA|NA|NA	I	PAP2 superfamily
MAG.T21.45_01132	760192.Halhy_1512	8.6e-91	340.9	Sphingobacteriia													Bacteria	1IQVH@117747,4NEF4@976,COG0793@1,COG0793@2	NA|NA|NA	M	PDZ DHR GLGF domain protein
MAG.T21.45_01133	760192.Halhy_1511	4.6e-30	137.1	Sphingobacteriia	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02888	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1ISVP@117747,4NSHE@976,COG0261@1,COG0261@2	NA|NA|NA	J	This protein binds to 23S rRNA in the presence of protein L20
MAG.T21.45_01134	1122176.KB903539_gene1303	3.9e-31	141.0	Sphingobacteriia	rpmA	GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904		ko:K02879,ko:K02890,ko:K02899	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IT8M@117747,4NS7T@976,COG0211@1,COG0211@2,COG3743@1,COG3743@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL27 family
MAG.T21.45_01135	1250006.JHZZ01000001_gene1412	2.5e-18	99.4	Polaribacter	batE												Bacteria	1HYKU@117743,3VVPU@52959,4NF5V@976,COG0457@1,COG0457@2,COG3103@1,COG3103@2	NA|NA|NA	T	Bacterial SH3 domain homologues
MAG.T21.45_01136	1122176.KB903557_gene4052	4.1e-113	415.6	Sphingobacteriia	lptA			ko:K09774					ko00000,ko02000	1.B.42.1			Bacteria	1IP5G@117747,4NDU3@976,COG1452@1,COG1452@2,COG1934@1,COG1934@2	NA|NA|NA	M	OstA-like protein
MAG.T21.45_01138	1122179.KB890413_gene4932	3.2e-51	208.0	Sphingobacteriia				ko:K03559					ko00000,ko02000	1.A.30.2.1			Bacteria	1J03A@117747,4NKT1@976,COG0848@1,COG0848@2	NA|NA|NA	U	Biopolymer transport protein ExbD/TolR
MAG.T21.45_01139	1122179.KB890413_gene4933	8.4e-75	286.6	Sphingobacteriia				ko:K03559					ko00000,ko02000	1.A.30.2.1			Bacteria	1IZ0M@117747,4NHYQ@976,COG0848@1,COG0848@2	NA|NA|NA	U	Biopolymer transport protein ExbD/TolR
MAG.T21.45_01141	1122179.KB890413_gene4935	1.9e-86	325.9	Sphingobacteriia	exbB			ko:K03561					ko00000,ko02000	1.A.30.2.1			Bacteria	1IXAP@117747,4NEA2@976,COG0811@1,COG0811@2	NA|NA|NA	U	MotA/TolQ/ExbB proton channel family
MAG.T21.45_01143	1051646.VITU9109_19757	4.7e-68	264.6	Vibrionales	tatD			ko:K03424					ko00000,ko01000				Bacteria	1MUC0@1224,1SPRE@1236,1XUSU@135623,COG0084@1,COG0084@2	NA|NA|NA	L	COG0084 Mg-dependent DNase
MAG.T21.45_01144	760192.Halhy_4833	2.4e-59	235.3	Bacteroidetes	rnhA		3.1.26.4	ko:K03469,ko:K06993	ko03030,map03030				ko00000,ko00001,ko01000,ko03032				Bacteria	4NI01@976,COG0328@1,COG0328@2,COG3341@1,COG3341@2	NA|NA|NA	L	double-stranded RNA RNA-DNA hybrid binding protein
MAG.T21.45_01145	760192.Halhy_4834	4.1e-61	241.1	Sphingobacteriia	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462					ko00000,ko01000				Bacteria	1IRF3@117747,4NFB4@976,COG0242@1,COG0242@2	NA|NA|NA	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MAG.T21.45_01146	1122176.KB903534_gene2120	1.4e-30	139.4	Sphingobacteriia	yqgF	GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360		ko:K07447					ko00000,ko01000				Bacteria	1ISBS@117747,4NQ8B@976,COG0816@1,COG0816@2	NA|NA|NA	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MAG.T21.45_01147	1122605.KB893648_gene3563	1.8e-90	339.7	Bacteroidetes	manA		1.14.13.81,5.3.1.8,5.4.2.8	ko:K01809,ko:K01840,ko:K04035	ko00051,ko00520,ko00860,ko01100,ko01110,ko01130,map00051,map00520,map00860,map01100,map01110,map01130	M00114	R01818,R01819,R06265,R06266,R06267,R10068	RC00376,RC00408,RC00741,RC01491,RC01492,RC03042	ko00000,ko00001,ko00002,ko01000				Bacteria	4NKD9@976,COG1482@1,COG1482@2	NA|NA|NA	G	Phosphomannose isomerase type I
MAG.T21.45_01148	760192.Halhy_1451	9.8e-42	177.6	Sphingobacteriia													Bacteria	1IRCE@117747,4NEVD@976,COG3064@1,COG3064@2	NA|NA|NA	M	Type IX secretion system membrane protein PorP/SprF
MAG.T21.45_01149	760192.Halhy_1450	4.5e-177	627.5	Sphingobacteriia	gldK												Bacteria	1IP8A@117747,4NGY2@976,COG1262@1,COG1262@2	NA|NA|NA	S	PFAM Formylglycine-generating sulfatase enzyme
MAG.T21.45_01150	760192.Halhy_1449	1.6e-58	232.6	Sphingobacteriia	gldL												Bacteria	1ISRG@117747,28IG3@1,2Z8HM@2,4NFJR@976	NA|NA|NA	S	TIGRFAM gliding motility-associated protein GldL
MAG.T21.45_01151	760192.Halhy_1448	8.3e-168	597.0	Sphingobacteriia	gldM												Bacteria	1IR4A@117747,4PKZS@976,COG4219@1,COG4219@2	NA|NA|NA	KT	Gliding motility-associated protein GldM
MAG.T21.45_01152	760192.Halhy_1447	9.4e-81	307.0	Sphingobacteriia	gldN												Bacteria	1IQ08@117747,28H74@1,2Z7JF@2,4NFR0@976	NA|NA|NA	S	TIGRFAM gliding motility associated
MAG.T21.45_01153	760192.Halhy_1446	1e-172	613.6	Sphingobacteriia													Bacteria	1IQQR@117747,4NEK7@976,COG0507@1,COG0507@2,COG1112@1,COG1112@2	NA|NA|NA	L	DNA helicase
MAG.T21.45_01154	883096.HMPREF9699_00806	3.3e-17	94.4	Flavobacteriia				ko:K03972					ko00000				Bacteria	1I4FW@117743,4NSD1@976,COG0607@1,COG0607@2	NA|NA|NA	P	Sulfurtransferase
MAG.T21.45_01155	926549.KI421517_gene3951	2.2e-49	203.4	Cytophagia													Bacteria	47JDG@768503,4NE1M@976,COG0500@1,COG2226@2	NA|NA|NA	Q	methyltransferase
MAG.T21.45_01156	1122176.KB903537_gene1677	4.4e-187	661.0	Sphingobacteriia			2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026		R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2		Bacteria	1IUAV@117747,4NEK9@976,COG1215@1,COG1215@2	NA|NA|NA	M	Glycosyl transferase family 21
MAG.T21.45_01157	1122176.KB903537_gene1678	3.6e-70	271.6	Sphingobacteriia													Bacteria	1J0WP@117747,4PKIQ@976,COG0463@1,COG0463@2	NA|NA|NA	M	Glycosyl transferase family 2
MAG.T21.45_01158	760192.Halhy_1718	4.1e-156	558.1	Sphingobacteriia													Bacteria	1ISIT@117747,2DB82@1,2Z7PX@2,4NEW5@976	NA|NA|NA		
MAG.T21.45_01159	104623.Ser39006_02347	3.4e-40	172.2	Serratia	yeeZ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464											Bacteria	1MWVJ@1224,1RNDT@1236,4000V@613,COG0451@1,COG0451@2	NA|NA|NA	GM	NAD binding domain of 6-phosphogluconate dehydrogenase
MAG.T21.45_01160	760192.Halhy_1715	4.4e-91	341.3	Sphingobacteriia				ko:K07126					ko00000				Bacteria	1J0WN@117747,4NGW3@976,COG0790@1,COG0790@2	NA|NA|NA	S	Protein of unknown function (DUF2911)
MAG.T21.45_01161	760192.Halhy_1713	1e-53	216.1	Sphingobacteriia	mgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576	2.7.1.24,4.2.3.3	ko:K00859,ko:K01734	ko00640,ko00770,ko01100,ko01120,map00640,map00770,map01100,map01120	M00120	R00130,R01016	RC00002,RC00078,RC00424	ko00000,ko00001,ko00002,ko01000			iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992	Bacteria	1IT46@117747,4NQJ9@976,COG1803@1,COG1803@2	NA|NA|NA	G	methylglyoxal synthase
MAG.T21.45_01162	760192.Halhy_1875	8.3e-206	723.0	Sphingobacteriia	ahcY	GO:0000096,GO:0000097,GO:0000098,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0035375,GO:0035635,GO:0036094,GO:0036293,GO:0040007,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0070482,GO:0071268,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147				Bacteria	1IQTE@117747,4NEKE@976,COG0499@1,COG0499@2	NA|NA|NA	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MAG.T21.45_01163	760192.Halhy_4489	2.8e-47	195.3	Sphingobacteriia													Bacteria	1IRX6@117747,4NMRP@976,COG2370@1,COG2370@2	NA|NA|NA	O	HupE / UreJ protein
MAG.T21.45_01164	985255.APHJ01000027_gene884	2.8e-17	95.1	Gillisia													Bacteria	1I2EY@117743,2AE6H@1,2P6WD@244698,3140B@2,4NSDV@976	NA|NA|NA		
MAG.T21.45_01165	1313301.AUGC01000004_gene2314	6.9e-20	102.8	Bacteroidetes	yidD			ko:K03424,ko:K08998					ko00000,ko01000				Bacteria	4NV1N@976,COG0759@1,COG0759@2	NA|NA|NA	S	Could be involved in insertion of integral membrane proteins into the membrane
MAG.T21.45_01166	1122176.KB903532_gene2590	2e-124	452.2	Sphingobacteriia	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1INPZ@117747,4NFW6@976,COG0113@1,COG0113@2	NA|NA|NA	H	Belongs to the ALAD family
MAG.T21.45_01168	926549.KI421517_gene2934	7.1e-89	334.3	Cytophagia	acrA			ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718			ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6			Bacteria	47K2C@768503,4NEXN@976,COG0845@1,COG0845@2	NA|NA|NA	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAG.T21.45_01169	247490.KSU1_D1002	0.0	1513.0	Planctomycetes													Bacteria	2IX2G@203682,COG0841@1,COG0841@2	NA|NA|NA	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MAG.T21.45_01170	694427.Palpr_1859	1.2e-127	463.4	Porphyromonadaceae	tlyC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03699					ko00000,ko02042				Bacteria	22W70@171551,2FN9R@200643,4NE9R@976,COG1253@1,COG1253@2	NA|NA|NA	P	Transporter associated domain
MAG.T21.45_01171	247490.KSU1_D1001	5.1e-100	371.7	Planctomycetes													Bacteria	2IX0B@203682,COG1538@1,COG1538@2	NA|NA|NA	MU	outer membrane lipoprotein IbeB
MAG.T21.45_01172	760192.Halhy_4497	8.2e-81	306.6	Sphingobacteriia	rpoE			ko:K03088					ko00000,ko03021				Bacteria	1IRTH@117747,4NF93@976,COG1595@1,COG1595@2	NA|NA|NA	K	Belongs to the sigma-70 factor family. ECF subfamily
MAG.T21.45_01173	760192.Halhy_4498	0.0	1304.7	Sphingobacteriia	uvrA2			ko:K03701	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	1IQY4@117747,4NEHM@976,COG0178@1,COG0178@2	NA|NA|NA	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MAG.T21.45_01174	760192.Halhy_4867	3.6e-244	850.9	Sphingobacteriia	ubiD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000			iECO111_1330.ECO111_4669	Bacteria	1IR14@117747,4NHHV@976,COG0043@1,COG0043@2	NA|NA|NA	H	Belongs to the UbiD family
MAG.T21.45_01175	760192.Halhy_1423	3.9e-68	265.4	Sphingobacteriia	ate		2.3.2.29	ko:K21420			R11547,R11548	RC00064	ko00000,ko01000				Bacteria	1IYU3@117747,4NGKN@976,COG2935@1,COG2935@2	NA|NA|NA	O	Arginine-tRNA-protein transferase, C terminus
MAG.T21.45_01176	1392498.JQLH01000001_gene1794	5.7e-304	1050.4	Flavobacteriia													Bacteria	1HX4C@117743,4NEE8@976,COG4888@1,COG4888@2	NA|NA|NA	S	PFAM ASPIC and UnbV
MAG.T21.45_01177	504472.Slin_3979	1.3e-178	632.9	Cytophagia													Bacteria	47NFX@768503,4NI11@976,COG4198@1,COG4198@2	NA|NA|NA	S	Starch-binding associating with outer membrane
MAG.T21.45_01178	471854.Dfer_2438	8.2e-305	1053.1	Cytophagia													Bacteria	47Y7E@768503,4NZWU@976,COG4206@1,COG4206@2	NA|NA|NA	H	TonB dependent receptor
MAG.T21.45_01179	760192.Halhy_6548	4.5e-76	291.6	Sphingobacteriia	glk		2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1IUYW@117747,4NFZ1@976,COG1940@1,COG1940@2	NA|NA|NA	G	Glucokinase
MAG.T21.45_01180	1041826.FCOL_06985	2.2e-79	302.0	Flavobacterium													Bacteria	1IDMC@117743,2NYR8@237,4NJT2@976,COG5464@1,COG5464@2	NA|NA|NA	S	to proteins from other organisms
MAG.T21.45_01182	700598.Niako_5630	4.2e-21	107.1	Sphingobacteriia	lspA		3.4.23.36	ko:K03101	ko03060,map03060				ko00000,ko00001,ko01000,ko01002				Bacteria	1IQPW@117747,4NEZN@976,COG0597@1,COG0597@2	NA|NA|NA	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MAG.T21.45_01183	391598.FBBAL38_11469	4.7e-34	152.5	Flavobacteriia													Bacteria	1I4NQ@117743,4NTMP@976,COG4704@1,COG4704@2,COG5295@1,COG5295@2	NA|NA|NA	UW	Hep Hag repeat protein
MAG.T21.45_01184	1453505.JASY01000015_gene4479	5.5e-31	142.1	Flavobacterium													Bacteria	1IFYN@117743,2NXZ5@237,4PIA9@976,COG2207@1,COG2207@2	NA|NA|NA	K	Transcriptional regulator
MAG.T21.45_01185	616991.JPOO01000003_gene1858	4.1e-218	764.2	Arenibacter													Bacteria	1I7ZC@117743,23I1G@178469,4NFTJ@976,COG0665@1,COG0665@2	NA|NA|NA	E	FAD dependent oxidoreductase
MAG.T21.45_01186	938709.AUSH02000017_gene1064	3.1e-21	107.8	Bacteroidetes													Bacteria	2EVC1@1,33NSI@2,4NZJK@976	NA|NA|NA		
MAG.T21.45_01187	761193.Runsl_3539	2.5e-25	122.5	Cytophagia													Bacteria	47YFV@768503,4NIRV@976,COG2010@1,COG2010@2	NA|NA|NA	C	Protein of unknown function (DUF3365)
MAG.T21.45_01188	1121481.AUAS01000006_gene707	0.0	1310.8	Cytophagia													Bacteria	47MFW@768503,4NH6B@976,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2	NA|NA|NA	C	PFAM PBS lyase
MAG.T21.45_01189	1131812.JQMS01000001_gene40	1.2e-258	899.4	Flavobacterium	pacL		3.6.3.8	ko:K01537					ko00000,ko01000	3.A.3.2			Bacteria	1HY67@117743,2NT0H@237,4NERM@976,COG0474@1,COG0474@2	NA|NA|NA	P	Cation transporter/ATPase, N-terminus
MAG.T21.45_01190	468059.AUHA01000005_gene2450	6e-125	454.1	Sphingobacteriia													Bacteria	1IRNA@117747,4NE6W@976,COG1814@1,COG1814@2	NA|NA|NA	S	VIT family
MAG.T21.45_01191	1121373.KB903629_gene331	2.6e-198	698.4	Cytophagia				ko:K06876					ko00000				Bacteria	47N6N@768503,4NECD@976,COG3046@1,COG3046@2	NA|NA|NA	S	Deoxyribodipyrimidine photo-lyase-related protein
MAG.T21.45_01192	384765.SIAM614_29461	1.3e-23	115.9	Alphaproteobacteria													Bacteria	1RIJD@1224,2U9JZ@28211,COG1142@1,COG1142@2	NA|NA|NA	C	4fe-4S ferredoxin, iron-sulfur binding domain protein
MAG.T21.45_01193	1196028.ALEF01000042_gene699	5.9e-69	268.5	Virgibacillus													Bacteria	1TQPI@1239,4C6XY@84406,4HAV0@91061,COG1757@1,COG1757@2	NA|NA|NA	C	Na+/H+ antiporter family
MAG.T21.45_01194	313603.FB2170_06015	3.6e-135	488.0	Bacteroidetes													Bacteria	4P1NX@976,COG0667@1,COG0667@2	NA|NA|NA	CJ	Aldo/keto reductase family
MAG.T21.45_01196	485917.Phep_2982	1.3e-24	120.9	Sphingobacteriia													Bacteria	1IXMS@117747,4NTZ2@976,COG2207@1,COG2207@2	NA|NA|NA	K	PFAM Bacterial regulatory helix-turn-helix proteins, AraC family
MAG.T21.45_01197	649831.L083_1219	3.2e-71	277.3	Micromonosporales			3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100		R06200,R11307,R11308		ko00000,ko00001,ko01000		GH5,GH9		Bacteria	2I61V@201174,4DJUW@85008,COG4733@1,COG4733@2	NA|NA|NA	MU	Fibronectin type III domain
MAG.T21.45_01198	938709.AUSH02000020_gene1988	6.5e-37	162.5	Bacteria				ko:K20276	ko02024,map02024				ko00000,ko00001				Bacteria	COG3291@1,COG3291@2,COG4704@1,COG4704@2,COG5295@1,COG5295@2	NA|NA|NA	UW	Hep Hag repeat protein
MAG.T21.45_01201	933262.AXAM01000026_gene3073	1.2e-107	397.1	Deltaproteobacteria													Bacteria	1R4NN@1224,2WM2Z@28221,42NMV@68525,COG1672@1,COG1672@2	NA|NA|NA	S	PFAM Archaeal ATPase
MAG.T21.45_01202	313590.MED134_04439	1.9e-28	132.9	Dokdonia				ko:K13963	ko05146,map05146				ko00000,ko00001				Bacteria	1I06X@117743,37EA4@326319,4NJW9@976,COG0793@1,COG0793@2	NA|NA|NA	M	Peptidase family S41
MAG.T21.45_01203	886379.AEWI01000022_gene188	2.8e-23	114.0	Marinilabiliaceae													Bacteria	2G1BX@200643,3XKVM@558415,4PAZ3@976,COG3385@1,COG3385@2	NA|NA|NA	L	Domain of unknown function (DUF4372)
MAG.T21.45_01204	1168034.FH5T_11330	6.5e-135	486.9	Bacteroidia													Bacteria	2FPS3@200643,4NIN4@976,COG3385@1,COG3385@2	NA|NA|NA	L	Transposase IS4 family
MAG.T21.45_01206	760192.Halhy_3470	0.0	1482.2	Sphingobacteriia	mfd		2.4.1.129,3.4.16.4	ko:K03723,ko:K05365	ko00550,ko03420,map00550,map03420		R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011,ko03400		GT51		Bacteria	1IPC5@117747,4NEPA@976,COG1197@1,COG1197@2	NA|NA|NA	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MAG.T21.45_01207	760192.Halhy_2778	4.8e-72	277.7	Sphingobacteriia	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.297,2.1.1.33	ko:K02493,ko:K03439			R10806	RC00003,RC03279	ko00000,ko01000,ko03012,ko03016				Bacteria	1ISBF@117747,4NG4V@976,COG0220@1,COG0220@2	NA|NA|NA	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MAG.T21.45_01208	760192.Halhy_6146	7.7e-184	650.2	Sphingobacteriia													Bacteria	1IRGE@117747,4NEYU@976,COG1409@1,COG1409@2	NA|NA|NA	S	Purple acid Phosphatase, N-terminal domain
MAG.T21.45_01209	1089547.KB913013_gene1589	2.6e-84	318.5	Cytophagia			1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	47KFB@768503,4NFSY@976,COG4221@1,COG4221@2	NA|NA|NA	S	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAG.T21.45_01210	1121875.KB907547_gene3455	2e-149	535.8	Flavobacteriia				ko:K03319					ko00000	2.A.47			Bacteria	1I05J@117743,4NPCY@976,COG0471@1,COG0471@2	NA|NA|NA	P	2-oxoglutarate translocator
MAG.T21.45_01211	1408433.JHXV01000001_gene994	3.9e-57	228.8	Bacteroidetes													Bacteria	2DMY6@1,32UCD@2,4NVHX@976	NA|NA|NA		
MAG.T21.45_01212	760192.Halhy_3608	4.7e-239	833.9	Sphingobacteriia	htpG	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071450,GO:0071451,GO:0071944,GO:1901700,GO:1901701		ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418				ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147				Bacteria	1IP5W@117747,4NDXZ@976,COG0326@1,COG0326@2	NA|NA|NA	O	Heat shock protein Hsp90
MAG.T21.45_01213	1122176.KB903548_gene1196	5.9e-80	304.7	Sphingobacteriia	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391		ko:K03703	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	1IZVS@117747,4NGEV@976,COG0322@1,COG0322@2	NA|NA|NA	L	Domain of unknown function (DUF4837)
MAG.T21.45_01214	1122179.KB890436_gene1327	3.7e-142	511.1	Sphingobacteriia	moxR			ko:K03924					ko00000,ko01000				Bacteria	1INQ9@117747,4NDVZ@976,COG0714@1,COG0714@2	NA|NA|NA	S	PFAM ATPase family associated with various cellular activities (AAA)
MAG.T21.45_01215	1122176.KB903554_gene3958	0.0	1226.1	Bacteroidetes													Bacteria	4NESU@976,COG4447@1,COG4447@2	NA|NA|NA	T	PFAM BNR Asp-box repeat
MAG.T21.45_01217	760192.Halhy_2080	8.6e-61	241.1	Bacteroidetes	rip3	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944		ko:K06212,ko:K06402					ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3			Bacteria	4NK8R@976,COG0517@1,COG0517@2,COG1994@1,COG1994@2	NA|NA|NA	S	Belongs to the peptidase M50B family
MAG.T21.45_01218	616991.JPOO01000001_gene3143	3.2e-45	188.3	Arenibacter	ydjA												Bacteria	1I1BE@117743,23G63@178469,4NMUE@976,COG0778@1,COG0778@2	NA|NA|NA	C	Nitroreductase family
MAG.T21.45_01219	1122176.KB903544_gene775	1.9e-276	958.4	Sphingobacteriia	hppA		3.6.1.1	ko:K15987	ko00190,map00190				ko00000,ko00001,ko01000	3.A.10.1			Bacteria	1IURE@117747,4NF2I@976,COG3808@1,COG3808@2	NA|NA|NA	C	Inorganic H+ pyrophosphatase
MAG.T21.45_01220	866536.Belba_3611	1.7e-108	399.4	Bacteroidetes			1.14.15.3	ko:K00496,ko:K10616,ko:K15757	ko00071,ko00622,ko00623,ko00930,ko01100,ko01120,ko01220,map00071,map00622,map00623,map00930,map01100,map01120,map01220	M00419,M00537	R01347,R02281,R02550,R05266,R05288,R05442,R05443,R06945	RC00269,RC00478	ko00000,ko00001,ko00002,ko01000				Bacteria	4NIC2@976,COG3239@1,COG3239@2	NA|NA|NA	I	fatty acid desaturase
MAG.T21.45_01221	929703.KE386491_gene195	3e-37	161.4	Bacteroidetes			4.4.1.5	ko:K01759	ko00620,map00620		R02530	RC00004,RC00740	ko00000,ko00001,ko01000				Bacteria	4NT9B@976,COG0346@1,COG0346@2	NA|NA|NA	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MAG.T21.45_01222	760192.Halhy_2954	1.4e-36	159.8	Sphingobacteriia													Bacteria	1IS1U@117747,4NH3F@976,COG1280@1,COG1280@2	NA|NA|NA	E	Lysine exporter protein (Lyse ygga)
MAG.T21.45_01223	760192.Halhy_2951	8.3e-181	640.2	Sphingobacteriia				ko:K18538					ko00000				Bacteria	1J0X4@117747,4PP1M@976,COG1541@1,COG1541@2	NA|NA|NA	H	GH3 auxin-responsive promoter
MAG.T21.45_01224	760192.Halhy_3015	1e-74	287.0	Sphingobacteriia				ko:K12976					ko00000,ko01000,ko01005				Bacteria	1J0BJ@117747,4NUEN@976,COG3637@1,COG3637@2	NA|NA|NA	M	Outer membrane protein beta-barrel domain
MAG.T21.45_01225	760192.Halhy_2904	2.4e-33	149.1	Sphingobacteriia													Bacteria	1IYVB@117747,4P9NR@976,COG4974@1,COG4974@2	NA|NA|NA	L	Plasmid pRiA4b ORF-3-like protein
MAG.T21.45_01226	760192.Halhy_2753	9.7e-82	310.1	Sphingobacteriia	scpA	GO:0003674,GO:0005488,GO:0005515,GO:0042802		ko:K05896					ko00000,ko03036				Bacteria	1IPTD@117747,4NJQE@976,COG1354@1,COG1354@2	NA|NA|NA	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MAG.T21.45_01227	1313421.JHBV01000024_gene5012	6.7e-61	240.7	Sphingobacteriia	rsmI_1		2.1.1.198	ko:K07056					ko00000,ko01000,ko03009				Bacteria	1IPGI@117747,4NDXE@976,COG0313@1,COG0313@2	NA|NA|NA	H	Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase
MAG.T21.45_01228	760192.Halhy_2542	3.5e-148	531.2	Sphingobacteriia	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000			iAF1260.b0750,iAPECO1_1312.APECO1_1338,iB21_1397.B21_00692,iBWG_1329.BWG_0602,iECBD_1354.ECBD_2917,iECB_1328.ECB_00703,iECDH10B_1368.ECDH10B_0817,iECDH1ME8569_1439.ECDH1ME8569_0703,iECD_1391.ECD_00703,iECED1_1282.ECED1_0711,iECOK1_1307.ECOK1_0750,iECP_1309.ECP_0761,iECS88_1305.ECS88_0766,iECSP_1301.ECSP_0802,iECs_1301.ECs0778,iETEC_1333.ETEC_0754,iEcDH1_1363.EcDH1_2892,iEcolC_1368.EcolC_2912,iJN746.PP_1231,iJO1366.b0750,iJR904.b0750,iUMN146_1321.UM146_13905,iUTI89_1310.UTI89_C0747,iY75_1357.Y75_RS03905,iZ_1308.Z0919	Bacteria	1INZ3@117747,4NDVX@976,COG0379@1,COG0379@2	NA|NA|NA	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MAG.T21.45_01229	1122179.KB890426_gene3946	5.3e-169	600.9	Sphingobacteriia				ko:K12941					ko00000,ko01002				Bacteria	1IRNW@117747,4NEKH@976,COG1473@1,COG1473@2	NA|NA|NA	S	Peptidase dimerisation domain
MAG.T21.45_01230	760192.Halhy_3013	3.1e-87	328.6	Sphingobacteriia	GalU		2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	1J0X5@117747,4NF32@976,COG1209@1,COG1209@2	NA|NA|NA	M	Nucleotidyl transferase
MAG.T21.45_01231	760192.Halhy_2790	5.5e-121	441.4	Sphingobacteriia													Bacteria	1IP2Z@117747,4NFS7@976,COG2067@1,COG2067@2	NA|NA|NA	I	membrane protein involved in aromatic hydrocarbon degradation
MAG.T21.45_01232	1122179.KB890413_gene4758	2.4e-13	83.6	Bacteroidetes													Bacteria	2CJG0@1,332HN@2,4NVWF@976	NA|NA|NA		
MAG.T21.45_01233	760192.Halhy_2788	4.3e-235	820.5	Sphingobacteriia	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1IQ4M@117747,4NEAF@976,COG0442@1,COG0442@2	NA|NA|NA	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
MAG.T21.45_01235	760192.Halhy_6184	1.1e-32	146.7	Bacteroidetes				ko:K13652					ko00000,ko03000				Bacteria	4NMS1@976,COG3449@1,COG3449@2	NA|NA|NA	L	SOUL heme-binding protein
MAG.T21.45_01236	760192.Halhy_3652	3.2e-163	581.3	Sphingobacteriia	gfo		1.1.99.28	ko:K00118					ko00000,ko01000				Bacteria	1IPB6@117747,4NE75@976,COG0673@1,COG0673@2	NA|NA|NA	S	Glucose--fructose oxidoreductase
MAG.T21.45_01237	1121889.AUDM01000007_gene1045	6.9e-182	643.7	Flavobacterium			3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147				Bacteria	1HZ7R@117743,2NS8K@237,4NG3D@976,COG1785@1,COG1785@2	NA|NA|NA	P	Belongs to the alkaline phosphatase family
MAG.T21.45_01238	1305737.JAFX01000001_gene1480	5e-39	166.8	Cytophagia													Bacteria	47RHE@768503,4NQS7@976,COG1396@1,COG1396@2	NA|NA|NA	K	Helix-turn-helix domain
MAG.T21.45_01239	1492738.FEM21_26770	1.3e-41	175.6	Flavobacterium		GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0045926,GO:0045927,GO:0046483,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0065007,GO:0070482,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360											Bacteria	1I24W@117743,2NX5Y@237,4NPPR@976,COG4679@1,COG4679@2	NA|NA|NA	S	Phage derived protein Gp49-like (DUF891)
MAG.T21.45_01240	1296416.JACB01000010_gene1664	3.9e-25	120.9	Bacteria													Bacteria	COG1514@1,COG1514@2	NA|NA|NA	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MAG.T21.45_01241	880070.Cycma_0604	2.7e-16	90.9	Cytophagia	XK27_08510			ko:K06919					ko00000				Bacteria	47TY1@768503,4NI8N@976,COG1061@1,COG1061@2,COG4951@1,COG4951@2	NA|NA|NA	L	Type III restriction enzyme, res subunit
MAG.T21.45_01242	880070.Cycma_0604	4.9e-33	146.7	Cytophagia	XK27_08510			ko:K06919					ko00000				Bacteria	47TY1@768503,4NI8N@976,COG1061@1,COG1061@2,COG4951@1,COG4951@2	NA|NA|NA	L	Type III restriction enzyme, res subunit
MAG.T21.45_01243	880070.Cycma_0602	3.9e-177	627.5	Cytophagia	arsR		1.20.4.1	ko:K03741,ko:K03892					ko00000,ko01000,ko03000				Bacteria	47MWT@768503,4NFBY@976,COG0640@1,COG0640@2,COG3177@1,COG3177@2	NA|NA|NA	K	PFAM Fic DOC family
MAG.T21.45_01244	1288963.ADIS_4862	2.4e-45	188.0	Bacteroidetes													Bacteria	4PMNR@976,COG1426@1,COG1426@2	NA|NA|NA	K	Helix-turn-helix domain
MAG.T21.45_01245	1121887.AUDK01000011_gene151	3.8e-78	298.1	Bacteria	bioH		2.1.1.197,3.1.1.85	ko:K02169,ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09543,R09725	RC00003,RC00460,RC00461	ko00000,ko00001,ko00002,ko01000				Bacteria	COG2267@1,COG2267@2	NA|NA|NA	I	carboxylic ester hydrolase activity
MAG.T21.45_01246	1121129.KB903359_gene1750	2e-67	262.3	Bacteroidetes													Bacteria	4PPJA@976,COG0702@1,COG0702@2	NA|NA|NA	GM	NmrA-like family
MAG.T21.45_01247	714943.Mucpa_4680	1.5e-66	259.6	Sphingobacteriia				ko:K07124					ko00000				Bacteria	1IRS4@117747,4NIAI@976,COG0300@1,COG0300@2	NA|NA|NA	S	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAG.T21.45_01248	760192.Halhy_4897	4.9e-10	70.9	Sphingobacteriia													Bacteria	1J0F3@117747,31BQE@2,4PQ0A@976,COG2259@1	NA|NA|NA	S	DoxX-like family
MAG.T21.45_01250	1121889.AUDM01000046_gene223	1.1e-61	242.7	Bacteroidetes				ko:K06880					ko00000,ko01000,ko01504				Bacteria	4NX7I@976,COG2312@1,COG2312@2	NA|NA|NA	S	Erythromycin esterase
MAG.T21.45_01251	562743.JH976438_gene2141	3.5e-12	78.6	Bacilli													Bacteria	1V2CU@1239,28YFR@1,2ZC1W@2,4HM2G@91061	NA|NA|NA		
MAG.T21.45_01252	1122915.AUGY01000104_gene4769	9.2e-48	196.8	Paenibacillaceae	ycaK		1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418		R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000				Bacteria	1VC9F@1239,275KS@186822,4HKPT@91061,COG2249@1,COG2249@2	NA|NA|NA	S	NADPH-dependent FMN reductase
MAG.T21.45_01253	1121007.AUML01000052_gene3184	5.3e-32	144.4	Flavobacteriia													Bacteria	1I1QW@117743,4NG9D@976,COG0664@1,COG0664@2	NA|NA|NA	T	- catabolite gene activator and regulatory subunit of cAMP-dependent protein
MAG.T21.45_01254	1121887.AUDK01000011_gene150	7.9e-68	263.5	Flavobacterium													Bacteria	1I385@117743,2NWXI@237,4NNYU@976,COG0664@1,COG0664@2	NA|NA|NA	T	- catabolite gene activator and regulatory subunit of cAMP-dependent protein
MAG.T21.45_01255	755732.Fluta_3714	0.0	1778.1	Bacteroidetes				ko:K03296					ko00000	2.A.6.2			Bacteria	4NDZG@976,COG0841@1,COG0841@2	NA|NA|NA	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MAG.T21.45_01256	755732.Fluta_3715	1.1e-152	546.2	Flavobacteriia													Bacteria	1HZGV@117743,4NF23@976,COG0845@1,COG0845@2	NA|NA|NA	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAG.T21.45_01257	755732.Fluta_3716	3.1e-192	677.9	Flavobacteriia				ko:K03287					ko00000	1.B.17			Bacteria	1HYW1@117743,4NF4X@976,COG1538@1,COG1538@2	NA|NA|NA	MU	Outer membrane efflux protein
MAG.T21.45_01258	1267211.KI669560_gene836	1.1e-85	322.8	Sphingobacteriia													Bacteria	1ITV0@117747,4NJJM@976,COG1309@1,COG1309@2	NA|NA|NA	K	YsiA-like protein, C-terminal region
MAG.T21.45_01259	1267211.KI669560_gene835	1.7e-83	315.8	Sphingobacteriia													Bacteria	1IZJQ@117747,2CZCF@1,32T62@2,4NT3B@976	NA|NA|NA		
MAG.T21.45_01260	755732.Fluta_3723	2.8e-59	234.6	Bacteroidetes													Bacteria	2B9TV@1,3236R@2,4P2DP@976	NA|NA|NA		
MAG.T21.45_01261	1410613.JNKF01000010_gene353	1.2e-59	237.3	Bacteria			2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	COG0286@1,COG0286@2	NA|NA|NA	V	site-specific DNA-methyltransferase (adenine-specific) activity
MAG.T21.45_01262	661478.OP10G_4057	3.2e-97	362.8	Bacteria			3.2.1.35,3.2.1.52	ko:K01197,ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00076,M00077,M00079	R00022,R06004,R07824,R07825,R10905,R11316	RC00049	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042,ko03110		GH20		Bacteria	COG3525@1,COG3525@2	NA|NA|NA	G	beta-N-acetylhexosaminidase activity
MAG.T21.45_01263	929703.KE386491_gene1383	4.2e-113	414.8	Cytophagia				ko:K21430					ko00000,ko01000				Bacteria	47KSC@768503,4NEZC@976,COG2133@1,COG2133@2	NA|NA|NA	G	PFAM Glucose Sorbosone dehydrogenase
MAG.T21.45_01264	1189612.A33Q_0080	3.2e-40	171.8	Bacteroidetes													Bacteria	4P4XS@976,COG0457@1,COG0457@2	NA|NA|NA	S	Protein of unknown function (DUF2911)
MAG.T21.45_01265	1034807.FBFL15_0868	3.2e-91	341.7	Flavobacterium													Bacteria	1IIAY@117743,2D63Q@1,2NTUB@237,32TKF@2,4NSJ4@976	NA|NA|NA		
MAG.T21.45_01266	1034807.FBFL15_0867	5.5e-33	147.5	Flavobacterium				ko:K07213	ko04978,map04978				ko00000,ko00001				Bacteria	1I1AA@117743,2NVZP@237,4NZ95@976,COG2608@1,COG2608@2	NA|NA|NA	P	Heavy-metal-associated domain
MAG.T21.45_01268	1121011.AUCB01000001_gene644	2.3e-98	367.5	Arenibacter	sbcC	GO:0000014,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1990238		ko:K03546					ko00000,ko03400				Bacteria	1HYCM@117743,23HXH@178469,4NH9H@976,COG0419@1,COG0419@2	NA|NA|NA	L	Putative exonuclease SbcCD, C subunit
MAG.T21.45_01269	1122226.AUHX01000005_gene2467	5.6e-79	301.6	Flavobacteriia	sbcD			ko:K03547					ko00000,ko03400				Bacteria	1HYF2@117743,4NEET@976,COG0420@1,COG0420@2	NA|NA|NA	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MAG.T21.45_01270	1267211.KI669560_gene1731	2.3e-55	221.9	Bacteroidetes													Bacteria	4NMAH@976,COG2335@1,COG2335@2	NA|NA|NA	M	Secreted and surface protein containing fasciclin-like repeats
MAG.T21.45_01271	760192.Halhy_6194	3e-139	501.9	Sphingobacteriia	dbpA	GO:0000027,GO:0000166,GO:0000339,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003729,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008135,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0010501,GO:0016043,GO:0016070,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0060255,GO:0065003,GO:0065007,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	3.6.4.13	ko:K05591,ko:K05592	ko03018,map03018				ko00000,ko00001,ko01000,ko03009,ko03019				Bacteria	1IQWW@117747,4NE4Z@976,COG0513@1,COG0513@2	NA|NA|NA	L	DEAD DEAH box helicase domain protein
MAG.T21.45_01272	504487.JCM19302_3544	8.2e-11	75.5	Flavobacteriia													Bacteria	1HZEZ@117743,4P0IA@976,COG0745@1,COG0745@2,COG3292@1,COG3292@2,COG5002@1,COG5002@2	NA|NA|NA	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MAG.T21.45_01273	1434325.AZQN01000004_gene1645	2.7e-06	60.5	Cytophagia	pdtaS		2.7.13.3	ko:K00936		M00839			ko00000,ko00002,ko01000,ko01001,ko02022				Bacteria	47N0D@768503,4NJ2Y@976,COG3292@1,COG3292@2,COG3920@1,COG3920@2	NA|NA|NA	T	Y_Y_Y domain
MAG.T21.45_01274	760192.Halhy_5493	4.5e-47	194.5	Bacteroidetes													Bacteria	2F17F@1,33U8J@2,4P2WT@976	NA|NA|NA		
MAG.T21.45_01275	760192.Halhy_0825	3e-60	238.0	Sphingobacteriia													Bacteria	1IXIJ@117747,4NN6Y@976,COG4430@1,COG4430@2	NA|NA|NA	S	Domain of unknown function (DUF1905)
MAG.T21.45_01276	1267211.KI669560_gene1390	6.8e-26	123.2	Sphingobacteriia			4.1.1.44,4.1.1.52	ko:K01607,ko:K22213	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220		R03470	RC00938	ko00000,ko00001,ko01000				Bacteria	1IVIK@117747,4NTAS@976,COG1359@1,COG1359@2	NA|NA|NA	S	Antibiotic biosynthesis monooxygenase
MAG.T21.45_01277	700598.Niako_0647	2.2e-48	198.4	Sphingobacteriia	yaeR			ko:K08234					ko00000				Bacteria	1IT2B@117747,4NQ7X@976,COG0346@1,COG0346@2	NA|NA|NA	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase
MAG.T21.45_01278	1121912.AUHD01000008_gene232	1.1e-186	659.8	Flavobacteriia			3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1HYSR@117743,4NFVX@976,COG2865@1,COG2865@2	NA|NA|NA	K	Putative ATP-dependent DNA helicase recG C-terminal
MAG.T21.45_01279	1121896.JMLU01000010_gene1348	1.3e-58	232.3	Flavobacterium				ko:K09959					ko00000				Bacteria	1I2VZ@117743,2NWA9@237,4NQEN@976,COG3564@1,COG3564@2	NA|NA|NA	S	Protein of unknown function (DUF779)
MAG.T21.45_01280	1121896.JMLU01000013_gene1273	9.5e-262	909.1	Flavobacterium	aldA			ko:K00138,ko:K18370	ko00010,ko00620,ko00640,ko01100,ko01110,ko01120,map00010,map00620,map00640,map01100,map01110,map01120		R00711,R10703	RC00047,RC00545	ko00000,ko00001,ko01000				Bacteria	1HWQG@117743,2P020@237,4NEB7@976,COG1012@1,COG1012@2	NA|NA|NA	C	Catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes
MAG.T21.45_01281	929562.Emtol_2717	1.5e-129	469.2	Cytophagia				ko:K07506					ko00000,ko03000				Bacteria	47Y3A@768503,4PKKC@976,COG4977@1,COG4977@2	NA|NA|NA	K	AraC-type transcriptional regulator N-terminus
MAG.T21.45_01282	1123278.KB893422_gene1600	3.1e-274	951.4	Cytophagia													Bacteria	47U7T@768503,4NG6P@976,COG0553@1,COG0553@2	NA|NA|NA	L	SNF2 family N-terminal domain
MAG.T21.45_01283	1122176.KB903539_gene1299	7.7e-45	188.7	Bacteroidetes													Bacteria	28IHG@1,2Z8IP@2,4NTKZ@976	NA|NA|NA		
MAG.T21.45_01284	1239962.C943_00433	1.3e-183	649.4	Cytophagia	cry2		4.1.99.3	ko:K01669					ko00000,ko01000,ko03400				Bacteria	47KG5@768503,4NH55@976,COG0415@1,COG0415@2	NA|NA|NA	L	PFAM FAD binding domain of DNA photolyase
MAG.T21.45_01285	997352.HMPREF9419_1034	1.7e-80	307.0	Bacteroidia													Bacteria	2G2PW@200643,4NJC9@976,COG1262@1,COG1262@2	NA|NA|NA	G	Sulfatase-modifying factor enzyme 1
MAG.T21.45_01287	1121012.AUKX01000074_gene36	3.1e-07	61.2	Arenibacter													Bacteria	1IC9Q@117743,23IHB@178469,4PA85@976,COG3668@1,COG3668@2	NA|NA|NA	S	Plasmid stabilization system
MAG.T21.45_01288	583355.Caka_0059	8.5e-50	204.1	Bacteria			3.2.1.83	ko:K20846					ko00000,ko01000		GH16		Bacteria	COG2273@1,COG2273@2	NA|NA|NA	G	xyloglucan:xyloglucosyl transferase activity
MAG.T21.45_01289	1122621.ATZA01000055_gene4189	1.2e-146	526.9	Sphingobacteriia			3.2.1.40	ko:K05989					ko00000,ko01000				Bacteria	1INYB@117747,4PMQ8@976,COG3408@1,COG3408@2	NA|NA|NA	G	Bacterial alpha-L-rhamnosidase C-terminal domain
MAG.T21.45_01290	870187.Thini_4326	7.3e-124	451.1	Thiotrichales													Bacteria	1N4VD@1224,1RXZT@1236,4620N@72273,COG1672@1,COG1672@2	NA|NA|NA	S	InterPro IPR018631 IPR012547
MAG.T21.45_01291	497964.CfE428DRAFT_1056	9.2e-96	357.5	Verrucomicrobia													Bacteria	46VGR@74201,COG3119@1,COG3119@2	NA|NA|NA	NP	Ig domain protein group 2 domain protein
MAG.T21.45_01292	485917.Phep_3489	5.2e-138	498.0	Sphingobacteriia			3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821		ko00000,ko00001,ko00002,ko01000				Bacteria	1IQA2@117747,4NFGI@976,COG3119@1,COG3119@2	NA|NA|NA	P	Sulfatase
MAG.T21.45_01293	1166018.FAES_3043	2.9e-104	385.6	Cytophagia													Bacteria	2DB8U@1,2Z7SW@2,47KH1@768503,4NEUK@976	NA|NA|NA	S	Alginate lyase
MAG.T21.45_01294	1123325.JHUV01000002_gene138	7.4e-16	90.9	Bacteria	yqiA	GO:0003674,GO:0003824,GO:0016787,GO:0016788		ko:K07000					ko00000				Bacteria	COG3150@1,COG3150@2	NA|NA|NA	G	esterase
MAG.T21.45_01295	1034807.FBFL15_2073	4e-100	371.3	Flavobacterium													Bacteria	1IDMC@117743,2NYR8@237,4NJT2@976,COG5464@1,COG5464@2	NA|NA|NA	S	to proteins from other organisms
MAG.T21.45_01297	1121373.KB903631_gene644	1.6e-37	162.5	Cytophagia													Bacteria	2C4GH@1,2ZFQN@2,47X38@768503,4P980@976	NA|NA|NA		
MAG.T21.45_01298	1121373.KB903631_gene645	7e-85	320.5	Bacteroidetes													Bacteria	2FBN7@1,343TB@2,4P61V@976	NA|NA|NA		
MAG.T21.45_01299	1121904.ARBP01000063_gene2828	1.5e-160	572.4	Cytophagia													Bacteria	47MK6@768503,4PN24@976,COG2152@1,COG2152@2	NA|NA|NA	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
MAG.T21.45_01300	929703.KE386491_gene1701	4.2e-168	597.8	Cytophagia				ko:K06926					ko00000				Bacteria	47NIN@768503,4NE5J@976,COG1106@1,COG1106@2	NA|NA|NA	S	AAA domain, putative AbiEii toxin, Type IV TA system
MAG.T21.45_01301	926556.Echvi_0466	4.9e-72	277.7	Cytophagia													Bacteria	2DMNB@1,32SNM@2,47QI4@768503,4NH88@976	NA|NA|NA	S	RloB-like protein
MAG.T21.45_01302	1408433.JHXV01000017_gene1551	1.5e-122	446.4	Cryomorphaceae													Bacteria	1HWQE@117743,2PA9A@246874,4NGND@976,COG1680@1,COG1680@2	NA|NA|NA	V	Beta-lactamase
MAG.T21.45_01303	1392488.JHZY01000004_gene1791	7.6e-207	726.5	Flavobacteriia				ko:K06926					ko00000				Bacteria	1I1VW@117743,4NE5J@976,COG1106@1,COG1106@2	NA|NA|NA	S	Psort location Cytoplasmic, score 8.96
MAG.T21.45_01304	313603.FB2170_06440	2.6e-133	481.9	Flavobacteriia													Bacteria	1I39H@117743,2CK9T@1,2Z7W9@2,4NH9E@976	NA|NA|NA		
MAG.T21.45_01305	1122621.ATZA01000059_gene4148	3.9e-49	201.4	Sphingobacteriia				ko:K06919					ko00000				Bacteria	1IT69@117747,4NM4B@976,COG5340@1,COG5340@2	NA|NA|NA	K	Psort location Cytoplasmic, score
MAG.T21.45_01306	1122621.ATZA01000059_gene4149	4.6e-71	275.0	Sphingobacteriia				ko:K09144					ko00000				Bacteria	1IS5Q@117747,4NMIN@976,COG2253@1,COG2253@2	NA|NA|NA	K	Nucleotidyl transferase AbiEii toxin, Type IV TA system
MAG.T21.45_01308	760192.Halhy_4739	3.5e-66	257.7	Sphingobacteriia	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113		ko:K02992	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IRJ7@117747,4NEEM@976,COG0049@1,COG0049@2	NA|NA|NA	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MAG.T21.45_01310	1122176.KB903535_gene1957	7.1e-57	226.5	Sphingobacteriia	rpsL	GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904		ko:K02950	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IS0J@117747,4NM3Y@976,COG0048@1,COG0048@2	NA|NA|NA	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MAG.T21.45_01311	760192.Halhy_4733	9.4e-53	213.8	Sphingobacteriia			3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100		R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004				Bacteria	1IUH8@117747,4NMMY@976,COG3884@1,COG3884@2	NA|NA|NA	I	Acyl-ACP thioesterase
MAG.T21.45_01312	1453505.JASY01000001_gene3579	4.2e-215	754.2	Flavobacterium	sglT			ko:K03307					ko00000	2.A.21			Bacteria	1HXMU@117743,2P028@237,4NE9S@976,COG4146@1,COG4146@2	NA|NA|NA	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MAG.T21.45_01313	929713.NIASO_01605	1.2e-139	502.7	Sphingobacteriia			1.13.99.1	ko:K00469	ko00053,ko00562,map00053,map00562		R01184	RC00465	ko00000,ko00001,ko01000				Bacteria	1IPN5@117747,2Z822@2,4NFQF@976,KOG1573@1	NA|NA|NA	S	Inositol oxygenase
MAG.T21.45_01314	1122176.KB903545_gene920	4.4e-73	280.8	Sphingobacteriia	dcd		3.5.4.13,3.6.1.23	ko:K01494,ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R00568,R02100,R02325,R11896	RC00002,RC00074	ko00000,ko00001,ko00002,ko01000,ko03400				Bacteria	1IPNT@117747,4NFRS@976,COG0717@1,COG0717@2	NA|NA|NA	F	Deoxycytidine triphosphate deaminase
MAG.T21.45_01315	760192.Halhy_1706	3.2e-286	991.1	Sphingobacteriia	csxA_2		3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142				ko00000,ko00001,ko01000				Bacteria	1INWW@117747,4NE7H@976,COG3250@1,COG3250@2	NA|NA|NA	G	PFAM Glycoside hydrolase family 2
MAG.T21.45_01316	313603.FB2170_14043	8.7e-140	503.8	Flavobacteriia			1.14.13.9,4.1.1.105,4.1.1.28	ko:K00486,ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00038,M00042	R00685,R00699,R00736,R01960,R02080,R02701,R04909	RC00046,RC00299	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1HZDC@117743,4NGZB@976,COG0076@1,COG0076@2	NA|NA|NA	E	Pyridoxal-dependent decarboxylase conserved domain
MAG.T21.45_01317	1122176.KB903536_gene1742	2e-263	915.6	Sphingobacteriia													Bacteria	1IQWB@117747,4NDU8@976,COG1629@1,COG4771@2	NA|NA|NA	P	TonB-dependent receptor plug
MAG.T21.45_01318	929703.KE386491_gene571	1.2e-101	377.1	Cytophagia													Bacteria	47M0U@768503,4NIN3@976,COG0521@1,COG0521@2	NA|NA|NA	H	Starch-binding associating with outer membrane
MAG.T21.45_01319	929703.KE386491_gene570	1.8e-08	65.9	Cytophagia													Bacteria	2FA5Y@1,342ER@2,47VFJ@768503,4P4D6@976	NA|NA|NA		
MAG.T21.45_01320	504472.Slin_0027	3.2e-132	478.8	Cytophagia													Bacteria	47RDI@768503,4NNWF@976,COG0657@1,COG0657@2,COG2755@1,COG2755@2	NA|NA|NA	I	Carboxylesterase family
MAG.T21.45_01321	1150600.ADIARSV_4246	1.8e-86	326.2	Sphingobacteriia				ko:K02529					ko00000,ko03000				Bacteria	1IP9G@117747,4NDW6@976,COG1609@1,COG1609@2	NA|NA|NA	K	PFAM periplasmic binding protein LacI transcriptional regulator
MAG.T21.45_01322	760192.Halhy_4240	2e-67	262.3	Sphingobacteriia	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100		R00966	RC00063	ko00000,ko00001,ko01000			iSB619.SA_RS11010	Bacteria	1IR1N@117747,4NFZM@976,COG0035@1,COG0035@2	NA|NA|NA	F	uracil phosphoribosyltransferase
MAG.T21.45_01323	1408473.JHXO01000010_gene3652	1.2e-68	267.3	Bacteroidia													Bacteria	2FR2H@200643,4NF79@976,COG0726@1,COG0726@2	NA|NA|NA	G	polysaccharide deacetylase
MAG.T21.45_01324	760192.Halhy_1890	5.2e-68	264.6	Sphingobacteriia													Bacteria	1IYAK@117747,28MPU@1,2ZAYW@2,4NXA9@976	NA|NA|NA		
MAG.T21.45_01325	1185876.BN8_00228	2.8e-133	481.5	Cytophagia	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100		R07767,R07768	RC01978	ko00000,ko00001,ko01000				Bacteria	47JGZ@768503,4NEB5@976,COG0320@1,COG0320@2	NA|NA|NA	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MAG.T21.45_01326	1122179.KB890436_gene1237	7.7e-72	277.7	Sphingobacteriia			3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147				Bacteria	1IPXF@117747,4NG3D@976,COG1785@1,COG1785@2	NA|NA|NA	P	Belongs to the alkaline phosphatase family
MAG.T21.45_01327	760192.Halhy_4228	2.8e-82	312.4	Sphingobacteriia	dprA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044424,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496		ko:K04096					ko00000				Bacteria	1IPSK@117747,4NF7T@976,COG0758@1,COG0758@2,COG1948@1,COG1948@2	NA|NA|NA	L	DNA protecting protein DprA
MAG.T21.45_01328	760192.Halhy_4317	2.9e-170	604.7	Sphingobacteriia	metC		2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K10764	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1INVN@117747,4NF0Q@976,COG0626@1,COG0626@2	NA|NA|NA	E	PFAM Cys Met metabolism
MAG.T21.45_01329	760192.Halhy_4162	5.2e-30	136.7	Sphingobacteriia	hupB			ko:K03530					ko00000,ko03032,ko03036,ko03400				Bacteria	1IYVW@117747,4NSK6@976,COG0776@1,COG0776@2	NA|NA|NA	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MAG.T21.45_01330	1122176.KB903539_gene1331	1.1e-71	277.3	Sphingobacteriia	appC			ko:K02034	ko02024,map02024	M00239			ko00000,ko00001,ko00002,ko02000	3.A.1.5			Bacteria	1IQI5@117747,4NGTQ@976,COG1173@1,COG1173@2	NA|NA|NA	EP	PFAM Binding-protein-dependent transport system inner membrane component
MAG.T21.45_01331	760192.Halhy_4223	6.2e-58	231.9	Sphingobacteriia	oppB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085		ko:K02033,ko:K02034,ko:K13894,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00349,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.21,3.A.1.5.24,3.A.1.5.25			Bacteria	1IRI6@117747,4NGIJ@976,COG0601@1,COG0601@2	NA|NA|NA	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MAG.T21.45_01332	760192.Halhy_4222	2.7e-135	489.2	Bacteria	oppA_5			ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24			Bacteria	COG0747@1,COG0747@2	NA|NA|NA	E	dipeptide transport
MAG.T21.45_01333	468059.AUHA01000002_gene1243	9.4e-63	247.3	Sphingobacteriia	yfcH			ko:K07071					ko00000				Bacteria	1IQB7@117747,4NINM@976,COG1090@1,COG1090@2	NA|NA|NA	S	PFAM NAD dependent epimerase dehydratase family
MAG.T21.45_01334	760192.Halhy_1881	6.3e-62	243.4	Bacteroidetes													Bacteria	4PP1D@976,COG0241@1,COG0241@2	NA|NA|NA	E	D,D-heptose 1,7-bisphosphate phosphatase
MAG.T21.45_01335	760192.Halhy_1882	4e-82	311.6	Sphingobacteriia	nlpD_1												Bacteria	1IT7G@117747,4NFZN@976,COG0739@1,COG0739@2	NA|NA|NA	M	peptidase M23
MAG.T21.45_01336	760192.Halhy_1883	4.5e-199	701.8	Sphingobacteriia													Bacteria	1J0PF@117747,4PKGA@976,COG1729@1,COG1729@2,COG3063@1,COG3063@2	NA|NA|NA	NU	Tetratricopeptide repeat
MAG.T21.45_01337	760192.Halhy_4308	3.1e-74	285.4	Sphingobacteriia	mltD_2												Bacteria	1IRYG@117747,4NH4W@976,COG0741@1,COG0741@2	NA|NA|NA	M	transglycosylase
MAG.T21.45_01338	760192.Halhy_4309	1.8e-47	195.7	Sphingobacteriia													Bacteria	1IS0K@117747,28NIX@1,2ZBK6@2,4NMEI@976	NA|NA|NA	S	Protein of unknown function (DUF2480)
MAG.T21.45_01339	760192.Halhy_4310	2.4e-56	225.3	Sphingobacteriia	scpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802		ko:K06024					ko00000,ko03036				Bacteria	1IS83@117747,4NPG3@976,COG1386@1,COG1386@2	NA|NA|NA	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MAG.T21.45_01340	926562.Oweho_0073	1.4e-28	134.4	Cryomorphaceae													Bacteria	1HY0A@117743,2PBF0@246874,4NE8J@976,COG2885@1,COG2885@2	NA|NA|NA	M	Belongs to the ompA family
MAG.T21.45_01341	1453498.LG45_11895	2.5e-56	224.9	Flavobacterium													Bacteria	1I4DA@117743,2NWRV@237,4NT0G@976,COG4319@1,COG4319@2	NA|NA|NA	S	ketosteroid isomerase
MAG.T21.45_01342	760192.Halhy_4120	4.4e-81	308.1	Sphingobacteriia				ko:K07214					ko00000				Bacteria	1IQ0H@117747,4NH62@976,COG0657@1,COG0657@2	NA|NA|NA	I	COG0657 Esterase lipase
MAG.T21.45_01343	1121104.AQXH01000006_gene2318	3.8e-80	305.1	Sphingobacteriia			3.1.4.55	ko:K06136,ko:K06167	ko00440,map00440		R10205	RC00296	ko00000,ko00001,ko01000				Bacteria	1IWBX@117747,4NGB4@976,COG1235@1,COG1235@2	NA|NA|NA	S	Beta-lactamase superfamily domain
MAG.T21.45_01344	1122176.KB903565_gene3413	2.1e-130	472.6	Bacteroidetes													Bacteria	4NF7U@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat protein
MAG.T21.45_01345	1122176.KB903567_gene3505	1.6e-101	376.7	Bacteria				ko:K19804					ko00000				Bacteria	COG2956@1,COG2956@2	NA|NA|NA	G	lipopolysaccharide metabolic process
MAG.T21.45_01346	1122176.KB903567_gene3506	1e-102	380.6	Sphingobacteriia													Bacteria	1IPB7@117747,4NEP1@976,COG2067@1,COG2067@2	NA|NA|NA	I	membrane
MAG.T21.45_01347	760192.Halhy_4283	1.1e-169	603.2	Sphingobacteriia	purH		2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1IP42@117747,4NEZD@976,COG0138@1,COG0138@2	NA|NA|NA	F	Bifunctional purine biosynthesis protein PurH
MAG.T21.45_01348	760192.Halhy_4179	2.3e-67	261.9	Sphingobacteriia	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100		R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000			iLJ478.TM0401	Bacteria	1IS2H@117747,4NE5R@976,COG1435@1,COG1435@2	NA|NA|NA	F	thymidine kinase
MAG.T21.45_01349	1313421.JHBV01000046_gene269	3e-11	75.9	Bacteroidetes													Bacteria	2EKSY@1,33EGP@2,4NXJC@976	NA|NA|NA	S	COG NOG23390 non supervised orthologous group
MAG.T21.45_01350	760192.Halhy_2810	3e-128	464.9	Sphingobacteriia	pfkA		2.7.1.11,2.7.1.90	ko:K00850,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019				Bacteria	1IPUF@117747,4NF8F@976,COG0205@1,COG0205@2	NA|NA|NA	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MAG.T21.45_01351	760192.Halhy_4157	1.8e-55	222.6	Sphingobacteriia	SEN0012												Bacteria	1IYDB@117747,4NGT3@976,COG0705@1,COG0705@2	NA|NA|NA	S	Rhomboid family
MAG.T21.45_01352	760192.Halhy_4345	7.1e-63	246.9	Sphingobacteriia	sigR_3			ko:K03088					ko00000,ko03021				Bacteria	1IPYA@117747,4NMM3@976,COG1595@1,COG1595@2	NA|NA|NA	K	Belongs to the sigma-70 factor family. ECF subfamily
MAG.T21.45_01353	760192.Halhy_4344	2.9e-26	125.2	Bacteroidetes				ko:K07726					ko00000,ko03000				Bacteria	4NY3C@976,COG1476@1,COG1476@2	NA|NA|NA	K	Helix-turn-helix XRE-family like proteins
MAG.T21.45_01354	909663.KI867150_gene1271	2.5e-30	139.8	Syntrophobacterales			3.4.22.15	ko:K01365,ko:K14475	ko04140,ko04142,ko04145,ko04210,ko04612,ko05143,ko05205,ko05323,ko05418,map04140,map04142,map04145,map04210,map04612,map05143,map05205,map05323,map05418				ko00000,ko00001,ko00537,ko01000,ko01002,ko03110				Bacteria	1RJ0M@1224,2MSFX@213462,2WRZX@28221,42V4Z@68525,COG4870@1,COG4870@2	NA|NA|NA	O	Papain family cysteine protease
MAG.T21.45_01355	1122176.KB903551_gene4256	2e-100	372.9	Sphingobacteriia													Bacteria	1IU97@117747,4NI5M@976,COG4409@1,COG4409@2	NA|NA|NA	G	exo-alpha-(2->6)-sialidase activity
MAG.T21.45_01356	743722.Sph21_0291	7.9e-20	103.6	Sphingobacteriia													Bacteria	1ITC9@117747,4NUTQ@976,COG2608@1,COG2608@2	NA|NA|NA	P	Heavy-metal-associated domain
MAG.T21.45_01357	760192.Halhy_2077	0.0	1386.3	Sphingobacteriia													Bacteria	1IVNR@117747,4NESU@976,COG4447@1,COG4447@2	NA|NA|NA	S	Sortilin, neurotensin receptor 3,
MAG.T21.45_01358	1121012.AUKX01000082_gene505	3.7e-18	96.7	Flavobacteriia													Bacteria	1I5I7@117743,4NRY6@976,COG1598@1,COG1598@2	NA|NA|NA	S	PFAM Uncharacterised protein family UPF0150
MAG.T21.45_01359	1121012.AUKX01000082_gene505	1e-17	95.5	Flavobacteriia													Bacteria	1I5I7@117743,4NRY6@976,COG1598@1,COG1598@2	NA|NA|NA	S	PFAM Uncharacterised protein family UPF0150
MAG.T21.45_01360	1239962.C943_00462	3.8e-116	424.5	Bacteroidetes													Bacteria	4NE39@976,COG1373@1,COG1373@2	NA|NA|NA	S	ATPase (AAA superfamily)
MAG.T21.45_01361	1353276.JADR01000002_gene2176	3.3e-10	70.9	Flavobacteriia	pglE		2.6.1.102,2.6.1.34	ko:K13010,ko:K15910,ko:K19430	ko00520,map00520		R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007				Bacteria	1HX99@117743,4NFAI@976,COG0399@1,COG0399@2	NA|NA|NA	E	Belongs to the DegT DnrJ EryC1 family
MAG.T21.45_01362	992406.RIA_0316	6.9e-40	169.5	Flavobacteriia	yoeB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006379,GO:0006401,GO:0006402,GO:0006417,GO:0006446,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016458,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0017148,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034655,GO:0042710,GO:0043021,GO:0043024,GO:0043170,GO:0044010,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044764,GO:0044877,GO:0045947,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0098795,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:2000112,GO:2000113		ko:K19158					ko00000,ko01000,ko02048				Bacteria	1I4GP@117743,4NSJD@976,COG4115@1,COG4115@2	NA|NA|NA	S	Toxin-antitoxin system, toxin component, Txe YoeB family
MAG.T21.45_01363	929556.Solca_2032	3.5e-28	130.6	Sphingobacteriia	yefM		2.3.1.15	ko:K08591,ko:K19158,ko:K19159	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004,ko02048				Bacteria	1IUAI@117747,4NT64@976,COG2161@1,COG2161@2	NA|NA|NA	D	Antitoxin component of a toxin-antitoxin (TA) module
MAG.T21.45_01365	1123248.KB893321_gene475	3.7e-51	208.4	Bacteroidetes													Bacteria	4NH6P@976,COG2159@1,COG2159@2	NA|NA|NA	S	Carbohydrate family 9 binding domain-like
MAG.T21.45_01366	760192.Halhy_3352	2.5e-134	485.7	Sphingobacteriia													Bacteria	1IQCS@117747,4NDXH@976,COG2866@1,COG2866@2	NA|NA|NA	E	Zinc carboxypeptidase
MAG.T21.45_01367	1178825.ALIH01000004_gene2923	5.9e-44	184.1	Flavobacteriia													Bacteria	1I23S@117743,4NP2C@976,COG2318@1,COG2318@2	NA|NA|NA	S	DinB superfamily
MAG.T21.45_01368	760192.Halhy_2076	2.5e-303	1048.1	Bacteroidetes													Bacteria	4NDXM@976,COG0612@1,COG0612@2	NA|NA|NA	S	Belongs to the peptidase M16 family
MAG.T21.45_01369	411154.GFO_0238	6.6e-51	208.0	Flavobacteriia	acdS		3.5.99.7,4.4.1.15	ko:K01505,ko:K05396	ko00270,map00270		R00997,R01874	RC00382,RC00419	ko00000,ko00001,ko01000				Bacteria	1HXPQ@117743,4NEP9@976,COG2515@1,COG2515@2	NA|NA|NA	E	1-aminocyclopropane-1-carboxylate deaminase
MAG.T21.45_01370	760192.Halhy_3501	2.5e-108	399.8	Sphingobacteriia			3.2.1.51	ko:K01206,ko:K07114,ko:K07126	ko00511,map00511				ko00000,ko00001,ko01000,ko02000,ko04147	1.A.13.2.2,1.A.13.2.3	GH29		Bacteria	1J0XA@117747,4PP1P@976,COG1729@1,COG1729@2	NA|NA|NA	S	Sporulation related domain
MAG.T21.45_01371	760192.Halhy_3500	3.3e-61	241.5	Sphingobacteriia	purN		2.1.2.2,6.3.2.6,6.3.4.13	ko:K11175,ko:K13713	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04144,R04325,R04326,R04591	RC00026,RC00064,RC00090,RC00162,RC00166,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQHJ@117747,4NNZP@976,COG0299@1,COG0299@2	NA|NA|NA	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MAG.T21.45_01372	1122176.KB903542_gene397	5.7e-33	149.1	Bacteroidetes													Bacteria	2DBNY@1,2ZA6F@2,4NTM4@976	NA|NA|NA		
MAG.T21.45_01373	1122176.KB903609_gene5217	5.1e-48	198.4	Sphingobacteriia													Bacteria	1IP87@117747,4NEE5@976,COG4485@1,COG4485@2	NA|NA|NA	S	Bacterial membrane protein YfhO
MAG.T21.45_01374	1191523.MROS_1148	2.8e-113	415.6	Bacteria													Bacteria	COG0438@1,COG0438@2	NA|NA|NA	M	transferase activity, transferring glycosyl groups
MAG.T21.45_01375	1286171.EAL2_c08000	1e-17	97.1	Clostridia													Bacteria	1VBV8@1239,24P5S@186801,COG5403@1,COG5403@2	NA|NA|NA	S	Bacterial protein of unknown function (DUF937)
MAG.T21.45_01376	1121904.ARBP01000050_gene4429	3.1e-143	515.4	Cytophagia	sacC	GO:0003674,GO:0003824,GO:0004553,GO:0004564,GO:0005975,GO:0005984,GO:0005985,GO:0005987,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016787,GO:0016798,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575	3.2.1.65,3.2.1.80	ko:K01212,ko:K03332	ko00051,ko00500,map00051,map00500		R00879,R05624,R11311	RC03278	ko00000,ko00001,ko01000		GH32		Bacteria	47KIP@768503,4NEYI@976,COG1621@1,COG1621@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 32 family
MAG.T21.45_01377	1356852.N008_15350	9.4e-103	380.2	Cytophagia													Bacteria	47K2I@768503,4NIZI@976,COG0535@1,COG0535@2	NA|NA|NA	S	4Fe-4S single cluster domain
MAG.T21.45_01378	391587.KAOT1_03682	3.2e-36	158.7	Flavobacteriia			5.4.99.23,5.4.99.24	ko:K06179,ko:K06180					ko00000,ko01000,ko03009				Bacteria	1HXRZ@117743,4NJNM@976,COG0564@1,COG0564@2	NA|NA|NA	J	RNA pseudouridylate synthase
MAG.T21.45_01379	760192.Halhy_2701	3.7e-29	134.0	Bacteroidetes													Bacteria	4NV5S@976,COG3255@1,COG3255@2	NA|NA|NA	I	SCP-2 sterol transfer family
MAG.T21.45_01380	760192.Halhy_3812	9.8e-64	250.0	Sphingobacteriia	hisI	GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.4.19,3.5.4.25,3.6.1.31,5.3.1.16	ko:K01496,ko:K01497,ko:K01523,ko:K01814,ko:K11755	ko00340,ko00740,ko00790,ko01100,ko01110,ko01230,ko02024,map00340,map00740,map00790,map01100,map01110,map01230,map02024	M00026,M00125	R00425,R04035,R04037,R04640	RC00002,RC00293,RC00945,RC01055,RC02504	ko00000,ko00001,ko00002,ko01000			iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iHN637.CLJU_RS05760,iSB619.SA_RS14110,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186	Bacteria	1INTS@117747,4NERE@976,COG0139@1,COG0139@2,COG0140@1,COG0140@2	NA|NA|NA	E	Histidine biosynthesis bifunctional protein hisIE
MAG.T21.45_01381	1122179.KB890427_gene3878	4e-104	384.4	Sphingobacteriia	hisF	GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	3.5.4.19,3.6.1.31	ko:K01663,ko:K02500,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037,R04558	RC00002,RC00010,RC01055,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000			iECO111_1330.ECO111_2749,iEcolC_1368.EcolC_1617,iHN637.CLJU_RS05755,iLJ478.TM1036,iSB619.SA_RS14115,iYL1228.KPN_02481	Bacteria	1INX3@117747,4NE16@976,COG0107@1,COG0107@2	NA|NA|NA	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MAG.T21.45_01382	760192.Halhy_2496	1.1e-96	359.8	Sphingobacteriia	punA		2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110		R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000				Bacteria	1IQGT@117747,4NE4J@976,COG0005@1,COG0005@2	NA|NA|NA	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MAG.T21.45_01383	760192.Halhy_3326	4.3e-174	617.5	Sphingobacteriia	mqnC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188	1.21.98.1,2.5.1.120,2.5.1.77	ko:K11779,ko:K11780,ko:K11781,ko:K11784,ko:K18285	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396,R10667	RC00021,RC01381,RC02329,RC03002,RC03007,RC03234	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQI2@117747,4NGTU@976,COG1060@1,COG1060@2	NA|NA|NA	H	Radical SAM
MAG.T21.45_01384	1122176.KB903544_gene813	1.6e-37	162.5	Sphingobacteriia	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576		ko:K09748					ko00000,ko03009				Bacteria	1IUA9@117747,4NQ32@976,COG0779@1,COG0779@2	NA|NA|NA	S	Required for maturation of 30S ribosomal subunits
MAG.T21.45_01385	760192.Halhy_3328	1.2e-185	656.0	Sphingobacteriia	nusA	GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141		ko:K02600					ko00000,ko03009,ko03021				Bacteria	1IQJC@117747,4NFGA@976,COG0195@1,COG0195@2	NA|NA|NA	K	Participates in both transcription termination and antitermination
MAG.T21.45_01386	760192.Halhy_3329	1.5e-301	1042.3	Sphingobacteriia	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464		ko:K02519					ko00000,ko03012,ko03029				Bacteria	1IQ0V@117747,4NGP3@976,COG0532@1,COG0532@2	NA|NA|NA	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MAG.T21.45_01387	1122179.KB890458_gene819	9.1e-36	156.4	Bacteroidetes													Bacteria	4NVY8@976,COG3339@1,COG3339@2	NA|NA|NA	S	Protein of unknown function (DUF1232)
MAG.T21.45_01388	760192.Halhy_2449	1.3e-208	733.4	Sphingobacteriia													Bacteria	1ITAS@117747,4NF1M@976,COG1404@1,COG1404@2	NA|NA|NA	O	Serine protease, subtilase family
MAG.T21.45_01389	760192.Halhy_4014	4.3e-188	664.8	Sphingobacteriia	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576		ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178			br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021				Bacteria	1IPNZ@117747,4NEFP@976,COG1158@1,COG1158@2	NA|NA|NA	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MAG.T21.45_01390	1122176.KB903565_gene3315	1.2e-153	549.7	Sphingobacteriia	serS		6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1IQMK@117747,4NED6@976,COG0172@1,COG0172@2	NA|NA|NA	J	seryl-tRNA synthetase
MAG.T21.45_01391	1122176.KB903565_gene3314	2.2e-72	278.9	Sphingobacteriia	yugP			ko:K06973					ko00000				Bacteria	1IRD0@117747,4NDWG@976,COG2738@1,COG2738@2	NA|NA|NA	S	PFAM Peptidase, membrane zinc metallopeptidase
MAG.T21.45_01392	760192.Halhy_4028	4.1e-61	241.1	Sphingobacteriia	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576		ko:K02838					ko00000,ko03012				Bacteria	1IRU0@117747,4NF95@976,COG0233@1,COG0233@2	NA|NA|NA	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MAG.T21.45_01393	760192.Halhy_4029	3.9e-14	83.2	Sphingobacteriia	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02914	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IU87@117747,4NUTV@976,COG0230@1,COG0230@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL34 family
MAG.T21.45_01394	760192.Halhy_4030	1.7e-172	612.8	Sphingobacteriia				ko:K20543					ko00000,ko02000	1.B.55.3			Bacteria	1J0XE@117747,4PKMW@976,COG1729@1,COG1729@2,COG4783@1,COG4783@2	NA|NA|NA	G	Tetratricopeptide repeat
MAG.T21.45_01395	1122179.KB890460_gene2131	2.2e-48	199.5	Sphingobacteriia	tonB			ko:K03832					ko00000,ko02000	2.C.1.1			Bacteria	1IY8A@117747,4NMG7@976,COG0810@1,COG0810@2	NA|NA|NA	M	Gram-negative bacterial TonB protein C-terminal
MAG.T21.45_01396	1122179.KB890460_gene2133	1.7e-42	178.7	Sphingobacteriia	gcvH			ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002				Bacteria	1IT1E@117747,4NQ35@976,COG0509@1,COG0509@2	NA|NA|NA	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MAG.T21.45_01397	760192.Halhy_1999	4e-192	677.6	Sphingobacteriia	gltA		2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1IQX9@117747,4NFXK@976,COG0372@1,COG0372@2	NA|NA|NA	C	Belongs to the citrate synthase family
MAG.T21.45_01398	760192.Halhy_1998	2.1e-68	265.4	Sphingobacteriia													Bacteria	1IQ2V@117747,4NEPX@976,COG0727@1,COG0727@2	NA|NA|NA	S	Protein of unknown function (DUF3109)
MAG.T21.45_01399	760192.Halhy_3240	1.1e-64	254.2	Sphingobacteriia													Bacteria	1IRU6@117747,4NEH3@976,COG1538@1,COG1538@2	NA|NA|NA	MU	Outer membrane efflux protein
MAG.T21.45_01400	1122176.KB903539_gene1402	3.5e-114	418.7	Sphingobacteriia	cvaA												Bacteria	1IR5J@117747,4NFEK@976,COG0845@1,COG0845@2	NA|NA|NA	M	Biotin-lipoyl like
MAG.T21.45_01401	760192.Halhy_3242	8.7e-147	527.3	Sphingobacteriia				ko:K02021					ko00000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21			Bacteria	1IQD5@117747,4NFJF@976,COG2274@1,COG2274@2	NA|NA|NA	V	ABC transporter transmembrane region
MAG.T21.45_01402	760192.Halhy_3244	5.2e-90	337.8	Sphingobacteriia	xerC			ko:K03733,ko:K04763					ko00000,ko03036				Bacteria	1IP1B@117747,4NE0E@976,COG4974@1,COG4974@2	NA|NA|NA	L	Tyrosine recombinase XerC
MAG.T21.45_01403	760192.Halhy_2465	4.3e-228	797.7	Sphingobacteriia			1.3.99.16	ko:K07303					ko00000,ko01000				Bacteria	1IPWF@117747,4NFFU@976,COG1529@1,COG1529@2	NA|NA|NA	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs
MAG.T21.45_01404	1123277.KB893179_gene3151	1.3e-57	229.2	Cytophagia			1.3.99.16	ko:K07302,ko:K07303					ko00000,ko01000				Bacteria	47XN3@768503,4NM72@976,COG2080@1,COG2080@2	NA|NA|NA	C	[2Fe-2S] binding domain
MAG.T21.45_01406	1122179.KB890432_gene4175	7.6e-36	157.5	Sphingobacteriia	recO	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360		ko:K03584	ko03440,map03440				ko00000,ko00001,ko03400				Bacteria	1IS4Q@117747,4NIBQ@976,COG1381@1,COG1381@2	NA|NA|NA	L	Involved in DNA repair and RecF pathway recombination
MAG.T21.45_01407	760192.Halhy_4176	2.4e-22	111.3	Sphingobacteriia													Bacteria	1IZ2F@117747,4NSB9@976,COG2963@1,COG2963@2	NA|NA|NA	L	Protein of unknown function (DUF2805)
MAG.T21.45_01408	760192.Halhy_2133	2.2e-101	375.9	Sphingobacteriia													Bacteria	1J0HU@117747,4PKIS@976,COG4339@1,COG4339@2	NA|NA|NA	S	SMART Metal-dependent phosphohydrolase, HD region
MAG.T21.45_01409	1150600.ADIARSV_2706	6.3e-122	444.1	Sphingobacteriia	gmd	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008446,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100		R00888	RC00402	ko00000,ko00001,ko01000				Bacteria	1IQAV@117747,4NEB6@976,COG1089@1,COG1089@2	NA|NA|NA	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MAG.T21.45_01410	760192.Halhy_2900	3.7e-107	394.8	Sphingobacteriia	fcl		1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100		R05692	RC01014	ko00000,ko00001,ko01000				Bacteria	1IQ44@117747,4NDV4@976,COG0451@1,COG0451@2	NA|NA|NA	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
MAG.T21.45_01411	760192.Halhy_3933	1.1e-11	75.5	Bacteroidetes													Bacteria	2ESEB@1,33JZ0@2,4NZ36@976	NA|NA|NA		
MAG.T21.45_01412	760192.Halhy_3934	4.3e-29	134.4	Bacteria													Bacteria	COG5378@1,COG5378@2	NA|NA|NA	S	PIN domain
MAG.T21.45_01413	761193.Runsl_4264	1.4e-16	92.4	Cytophagia			3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	47RZA@768503,4NGFJ@976,COG2865@1,COG2865@2	NA|NA|NA	K	Putative ATP-dependent DNA helicase recG C-terminal
MAG.T21.45_01414	938709.AUSH02000051_gene285	0.0	1301.2	Bacteria	ydaJ			ko:K20276,ko:K21449	ko02024,map02024				ko00000,ko00001,ko02000	1.B.40.2			Bacteria	COG1345@1,COG1345@2,COG1361@1,COG1361@2,COG3291@1,COG3291@2,COG3405@1,COG3405@2,COG4733@1,COG4733@2,COG5604@1,COG5604@2	NA|NA|NA	DZ	domain, Protein
MAG.T21.45_01415	1239962.C943_02268	1.6e-20	107.1	Cytophagia													Bacteria	47KE6@768503,4NEVD@976,COG3064@1,COG3064@2	NA|NA|NA	M	TIGRFAM Bacteroidetes-specific
MAG.T21.45_01416	760192.Halhy_4806	5.1e-180	637.5	Sphingobacteriia				ko:K21572					ko00000,ko02000	8.A.46.1,8.A.46.3			Bacteria	1INWG@117747,4NHFF@976,COG3193@1,COG3193@2	NA|NA|NA	S	Pfam:SusD
MAG.T21.45_01417	760192.Halhy_4807	0.0	1436.8	Sphingobacteriia													Bacteria	1INPM@117747,4P1Z5@976,COG1629@1,COG4771@2	NA|NA|NA	HP	TonB-dependent receptor plug
MAG.T21.45_01418	313603.FB2170_12386	1.1e-105	390.2	Maribacter	pat		2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1HXQE@117743,2PI2Y@252356,4NEW8@976,COG0079@1,COG0079@2	NA|NA|NA	E	Aminotransferase class-V
MAG.T21.45_01419	1123057.P872_16825	3.7e-81	308.1	Cytophagia													Bacteria	47NID@768503,4NJE8@976,COG5507@1,COG5507@2	NA|NA|NA	S	NIPSNAP
MAG.T21.45_01420	760192.Halhy_0222	1.6e-169	602.8	Sphingobacteriia													Bacteria	1IWUA@117747,4NG5Q@976,COG0308@1,COG0308@2	NA|NA|NA	E	Peptidase family M1 domain
MAG.T21.45_01421	1267211.KI669560_gene471	3.8e-200	704.5	Bacteroidetes													Bacteria	4NGUB@976,COG0308@1,COG0308@2	NA|NA|NA	E	peptidase M1
MAG.T21.45_01422	641524.ADICYQ_1978	4.6e-50	204.1	Cytophagia	ymaD												Bacteria	47S0N@768503,4P9T2@976,COG1764@1,COG1764@2	NA|NA|NA	O	OsmC-like protein
MAG.T21.45_01423	1086011.HJ01_00038	4.9e-31	140.2	Flavobacterium	pspE			ko:K03972					ko00000				Bacteria	1IMSI@117743,2NXC5@237,4PIDQ@976,COG0607@1,COG0607@2	NA|NA|NA	P	Rhodanese-like domain
MAG.T21.45_01424	929562.Emtol_0588	6.9e-19	99.4	Cytophagia	yibN		2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122		R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000				Bacteria	47SQ5@768503,4PA45@976,COG0607@1,COG0607@2	NA|NA|NA	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MAG.T21.45_01425	1506583.JQJY01000006_gene4437	4.1e-180	637.9	Flavobacterium	yhcX			ko:K11206					ko00000,ko01000				Bacteria	1HWST@117743,2NU5I@237,4NEAQ@976,COG0388@1,COG0388@2	NA|NA|NA	S	Carbon-nitrogen hydrolase
MAG.T21.45_01426	1041826.FCOL_06985	1.9e-113	415.6	Flavobacterium													Bacteria	1IDMC@117743,2NYR8@237,4NJT2@976,COG5464@1,COG5464@2	NA|NA|NA	S	to proteins from other organisms
MAG.T21.45_01427	1123276.KB893283_gene5128	2.1e-87	328.9	Bacteria				ko:K07018					ko00000				Bacteria	COG1073@1,COG1073@2	NA|NA|NA	S	thiolester hydrolase activity
MAG.T21.45_01428	927658.AJUM01000024_gene2616	8.2e-73	280.4	Bacteria													Bacteria	COG0726@1,COG0726@2	NA|NA|NA	G	polysaccharide deacetylase
MAG.T21.45_01429	761193.Runsl_1185	0.0	1925.2	Cytophagia				ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6			Bacteria	47K6B@768503,4NHMI@976,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2	NA|NA|NA	CG	Membrane-bound dehydrogenase domain protein
MAG.T21.45_01430	1121904.ARBP01000021_gene3576	5.2e-116	424.9	Cytophagia													Bacteria	47JKY@768503,4NFRB@976,COG3119@1,COG3119@2	NA|NA|NA	P	C-terminal region of aryl-sulfatase
MAG.T21.45_01432	760192.Halhy_2444	1.8e-135	489.6	Bacteroidetes													Bacteria	4P12U@976,COG1672@1,COG1672@2	NA|NA|NA	S	PD-(D/E)XK nuclease superfamily
MAG.T21.45_01433	388401.RB2150_07778	1.1e-91	343.6	Alphaproteobacteria			1.1.1.219	ko:K00091					ko00000,ko01000				Bacteria	1MW32@1224,2TTTU@28211,COG0451@1,COG0451@2	NA|NA|NA	GM	Nad-dependent epimerase dehydratase
MAG.T21.45_01434	1231626.CAHE_0179	5.5e-42	178.3	Cytophagia													Bacteria	47K3M@768503,4NJT2@976,COG5464@1,COG5464@2	NA|NA|NA	S	PD-(D/E)XK nuclease family transposase
MAG.T21.45_01435	1358423.N180_11055	1.2e-37	162.9	Sphingobacteriia													Bacteria	1IZGR@117747,4NJYW@976,COG3950@1,COG3950@2	NA|NA|NA	S	AAA domain, putative AbiEii toxin, Type IV TA system
MAG.T21.45_01436	1358423.N180_11055	1.5e-30	138.7	Sphingobacteriia													Bacteria	1IZGR@117747,4NJYW@976,COG3950@1,COG3950@2	NA|NA|NA	S	AAA domain, putative AbiEii toxin, Type IV TA system
MAG.T21.45_01437	1358423.N180_11055	2.5e-11	74.3	Sphingobacteriia													Bacteria	1IZGR@117747,4NJYW@976,COG3950@1,COG3950@2	NA|NA|NA	S	AAA domain, putative AbiEii toxin, Type IV TA system
MAG.T21.45_01438	1121897.AUGO01000009_gene2904	1.5e-45	189.9	Flavobacterium													Bacteria	1HYNZ@117743,2NX0F@237,4NR5M@976,COG2197@1,COG2197@2	NA|NA|NA	K	helix_turn_helix, Lux Regulon
MAG.T21.45_01439	1216967.L100_08719	1e-26	125.9	Elizabethkingia				ko:K19092					ko00000,ko02048				Bacteria	1ICQY@117743,34SD0@308865,4NQ43@976,COG3668@1,COG3668@2	NA|NA|NA	S	Belongs to the RelE toxin family
MAG.T21.45_01440	1216967.L100_08724	5.3e-21	106.7	Elizabethkingia				ko:K07746					ko00000,ko02048				Bacteria	1I46W@117743,34SD9@308865,4NSHD@976,COG3609@1,COG3609@2	NA|NA|NA	K	Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH
MAG.T21.45_01442	760192.Halhy_0611	5.1e-164	583.9	Sphingobacteriia			1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204		R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000				Bacteria	1IQ1G@117747,4NF83@976,COG1062@1,COG1062@2	NA|NA|NA	C	Alcohol dehydrogenase GroES-like domain
MAG.T21.45_01443	1123277.KB893239_gene1208	7.7e-123	446.8	Cytophagia													Bacteria	47MFK@768503,4NGMY@976,COG5285@1,COG5285@2	NA|NA|NA	Q	Phytanoyl-CoA dioxygenase (PhyH)
MAG.T21.45_01444	1123277.KB893239_gene1207	2.4e-73	282.3	Cytophagia	mltR												Bacteria	47MSY@768503,4NE6T@976,COG2207@1,COG2207@2	NA|NA|NA	K	helix_turn_helix, arabinose operon control protein
MAG.T21.45_01445	388413.ALPR1_14594	6.6e-243	846.7	Cytophagia				ko:K11085	ko02010,map02010				ko00000,ko00001,ko01000,ko02000	3.A.1.106			Bacteria	47MDS@768503,4NE19@976,COG2274@1,COG2274@2	NA|NA|NA	V	ABC transporter transmembrane region
MAG.T21.45_01446	761193.Runsl_0169	2e-198	699.1	Cytophagia			3.5.1.11,3.5.1.97	ko:K01434,ko:K07116	ko00311,ko01130,map00311,map01130		R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002				Bacteria	47K4Y@768503,4NGXQ@976,COG2366@1,COG2366@2	NA|NA|NA	S	Penicillin amidase
MAG.T21.45_01447	761193.Runsl_5542	1.6e-239	835.1	Cytophagia													Bacteria	47MMC@768503,4NGYE@976,COG3119@1,COG3119@2	NA|NA|NA	P	Protein of unknown function (DUF1501)
MAG.T21.45_01448	504472.Slin_0957	3.8e-215	754.6	Cytophagia													Bacteria	47K0Y@768503,4NG6K@976,COG4244@1,COG4244@2	NA|NA|NA	G	Protein of unknown function (DUF1549)
MAG.T21.45_01449	760192.Halhy_6170	9.5e-08	62.8	Bacteroidetes													Bacteria	2BF41@1,328W8@2,4P6H7@976	NA|NA|NA		
MAG.T21.45_01450	1158294.JOMI01000003_gene2141	2.7e-119	435.6	Bacteroidia			3.2.1.51	ko:K01206	ko00511,map00511				ko00000,ko00001,ko01000,ko04147		GH29		Bacteria	2FNFV@200643,4NEDX@976,COG3669@1,COG3669@2	NA|NA|NA	G	F5 8 type C domain protein
MAG.T21.45_01451	1122176.KB903544_gene781	7.6e-89	334.3	Bacteroidetes													Bacteria	4NG0X@976,COG3503@1,COG3503@2	NA|NA|NA	S	Protein of unknown function (DUF1624)
MAG.T21.45_01452	760192.Halhy_6385	3.6e-68	265.4	Bacteroidetes													Bacteria	2E7J5@1,3321E@2,4NWSR@976	NA|NA|NA		
MAG.T21.45_01453	760192.Halhy_6386	5.4e-157	561.2	Sphingobacteriia	gldG			ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1IR8V@117747,4NF62@976,COG3225@1,COG3225@2	NA|NA|NA	N	transport system involved in gliding motility, auxiliary component
MAG.T21.45_01454	760192.Halhy_6387	2.2e-70	272.3	Sphingobacteriia	gldF			ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1IRI4@117747,4NG5G@976,COG1277@1,COG1277@2	NA|NA|NA	S	TIGRFAM Gliding motility-associated ABC transporter permease protein GldF
MAG.T21.45_01456	760192.Halhy_6389	1.8e-98	365.9	Sphingobacteriia	gldA		3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115			Bacteria	1IQ87@117747,4NEH0@976,COG1131@1,COG1131@2	NA|NA|NA	V	COG1131 ABC-type multidrug transport system ATPase component
MAG.T21.45_01458	761193.Runsl_3512	1.1e-83	317.0	Cytophagia	ykfB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802			R10938	RC03309	ko00000,ko01000				Bacteria	47N8Q@768503,4NEBX@976,COG4948@1,COG4948@2	NA|NA|NA	M	mandelate racemase muconate lactonizing
MAG.T21.45_01461	760192.Halhy_4150	2.4e-271	941.8	Sphingobacteriia													Bacteria	1IR4H@117747,4NDVD@976,COG1506@1,COG1506@2	NA|NA|NA	E	peptidase S9 prolyl oligopeptidase active site domain protein
MAG.T21.45_01462	760192.Halhy_1868	4.1e-43	181.0	Sphingobacteriia				ko:K07071					ko00000				Bacteria	1ISKP@117747,4NQJG@976,COG4276@1,COG4276@2	NA|NA|NA	S	SRPBCC domain-containing protein
MAG.T21.45_01463	760192.Halhy_1866	2.9e-44	184.5	Sphingobacteriia	rnhA		3.1.1.24,3.1.26.4,4.1.1.44	ko:K01607,ko:K03469,ko:K14727	ko00362,ko01100,ko01120,ko01220,ko03030,map00362,map01100,map01120,map01220,map03030	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000,ko03032				Bacteria	1ISNQ@117747,4NNRB@976,COG0599@1,COG0599@2	NA|NA|NA	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MAG.T21.45_01464	760192.Halhy_1865	3.6e-265	921.0	Sphingobacteriia	pcrA		3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	1IP3C@117747,4NDWN@976,COG0210@1,COG0210@2	NA|NA|NA	L	DNA helicase
MAG.T21.45_01465	1121904.ARBP01000005_gene4837	3e-146	525.4	Cytophagia													Bacteria	47NFZ@768503,4NH6U@976,COG3356@1,COG3356@2	NA|NA|NA	S	PFAM Neutral alkaline nonlysosomal ceramidase
MAG.T21.45_01466	1250232.JQNJ01000001_gene238	1.1e-140	506.9	Flavobacteriia													Bacteria	1HYG1@117743,4NEA7@976,COG0624@1,COG0624@2	NA|NA|NA	E	Peptidase dimerisation domain
MAG.T21.45_01467	1123057.P872_19545	1.8e-148	532.3	Cytophagia			1.1.99.28	ko:K00118					ko00000,ko01000				Bacteria	47JGE@768503,4NE75@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase domain protein
MAG.T21.45_01468	760192.Halhy_1453	4.9e-16	90.1	Bacteria	feoA			ko:K04758					ko00000,ko02000				Bacteria	COG1918@1,COG1918@2	NA|NA|NA	P	iron ion homeostasis
MAG.T21.45_01469	760192.Halhy_1454	1.1e-226	793.1	Sphingobacteriia	feoB			ko:K04759					ko00000,ko02000	9.A.8.1			Bacteria	1IPAK@117747,4NEII@976,COG0370@1,COG0370@2	NA|NA|NA	P	transporter of a GTP-driven Fe(2 ) uptake system
MAG.T21.45_01470	760192.Halhy_4144	1.2e-198	699.5	Bacteroidetes													Bacteria	4NEWA@976,COG0664@1,COG0664@2	NA|NA|NA	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MAG.T21.45_01471	1237149.C900_00847	3.8e-20	103.6	Bacteria													Bacteria	COG1396@1,COG1396@2	NA|NA|NA	K	sequence-specific DNA binding
MAG.T21.45_01472	1237149.C900_00846	7.2e-12	75.9	Cytophagia			2.7.11.1	ko:K07154					ko00000,ko01000,ko01001,ko02048				Bacteria	47VW4@768503,4NTCR@976,COG3550@1,COG3550@2	NA|NA|NA	S	HipA N-terminal domain
MAG.T21.45_01473	1121896.JMLU01000022_gene2008	0.0	1414.1	Flavobacterium													Bacteria	1HZZE@117743,2NVDA@237,4NFKA@976,COG1002@1,COG1002@2	NA|NA|NA	V	Type II restriction enzyme, methylase subunits
MAG.T21.45_01475	929713.NIASO_17595	4.1e-106	391.7	Bacteroidetes													Bacteria	4NGY8@976,COG4804@1,COG4804@2	NA|NA|NA	S	Psort location Cytoplasmic, score 8.96
MAG.T21.45_01476	1235803.C825_02779	9.6e-115	420.2	Porphyromonadaceae													Bacteria	22WZQ@171551,2FN3T@200643,4NE0Q@976,COG4804@1,COG4804@2	NA|NA|NA	S	Protein of unknown function (DUF1016)
MAG.T21.45_01478	929562.Emtol_2970	1.7e-153	548.9	Bacteria													Bacteria	COG4249@1,COG4249@2	NA|NA|NA	S	B-1 B cell differentiation
MAG.T21.45_01479	411154.GFO_0922	2.3e-28	131.7	Flavobacteriia				ko:K18831					ko00000,ko02048,ko03000				Bacteria	1I2MM@117743,4NNXF@976,COG5499@1,COG5499@2	NA|NA|NA	K	transcription regulator containing HTH domain
MAG.T21.45_01480	929703.KE386491_gene1545	4.7e-106	391.3	Cytophagia													Bacteria	47KG1@768503,4NI2T@976,COG3292@1,COG3292@2	NA|NA|NA	T	PFAM Two component regulator propeller
MAG.T21.45_01481	391598.FBBAL38_11469	2.1e-53	216.9	Flavobacteriia													Bacteria	1I4NQ@117743,4NTMP@976,COG4704@1,COG4704@2,COG5295@1,COG5295@2	NA|NA|NA	UW	Hep Hag repeat protein
MAG.T21.45_01482	760192.Halhy_0880	9.6e-16	89.0	Bacteroidetes			4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230		R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000				Bacteria	4NJF4@976,COG1760@1,COG1760@2	NA|NA|NA	E	Serine dehydratase alpha chain
MAG.T21.45_01484	324925.Ppha_0057	2.2e-45	189.1	Bacteria	ps301												Bacteria	COG2944@1,COG2944@2	NA|NA|NA	K	sequence-specific DNA binding
MAG.T21.45_01485	471854.Dfer_5326	7.4e-30	136.3	Cytophagia	ps301												Bacteria	47PWI@768503,4NM9A@976,COG2944@1,COG2944@2,COG3600@1,COG3600@2	NA|NA|NA	K	Protein of unknown function (DUF4065)
MAG.T21.45_01486	760192.Halhy_1351	1.3e-33	149.4	Sphingobacteriia	fur			ko:K03711,ko:K09823,ko:K09825	ko02024,map02024				ko00000,ko00001,ko03000				Bacteria	1J0EB@117747,4NSES@976,COG0735@1,COG0735@2	NA|NA|NA	P	Ferric uptake regulator family
MAG.T21.45_01487	760192.Halhy_1353	3e-190	672.2	Sphingobacteriia				ko:K02014,ko:K16087					ko00000,ko02000	1.B.14,1.B.14.2			Bacteria	1IPUD@117747,4NFQD@976,COG1629@1,COG4771@2	NA|NA|NA	P	TonB-dependent receptor
MAG.T21.45_01488	760192.Halhy_1354	1.6e-41	176.0	Sphingobacteriia													Bacteria	1IZHS@117747,29TMV@1,30EVG@2,4NNPM@976	NA|NA|NA		
MAG.T21.45_01490	266748.HY04_13055	6.2e-12	77.4	Chryseobacterium													Bacteria	1I2MW@117743,2E78C@1,331S1@2,3ZUNK@59732,4NPWT@976	NA|NA|NA		
MAG.T21.45_01491	938709.AUSH02000020_gene1986	1.5e-54	220.7	Bacteroidetes													Bacteria	4NHDQ@976,COG3656@1,COG3656@2,COG5295@1,COG5295@2	NA|NA|NA	UW	fibronectin type III domain protein
MAG.T21.45_01492	1218103.CIN01S_07_01210	2.1e-124	452.2	Chryseobacterium			2.1.1.80,3.1.1.61,3.4.21.105	ko:K03631,ko:K13924,ko:K19225	ko02020,ko02030,map02020,map02030	M00506			ko00000,ko00001,ko00002,ko01000,ko01002,ko02022,ko02035,ko03400				Bacteria	1I80Q@117743,3ZP4B@59732,4NKAT@976,COG0497@1,COG0497@2	NA|NA|NA	L	DNA recombination
MAG.T21.45_01493	1218103.CIN01S_07_01200	7.2e-92	344.0	Chryseobacterium													Bacteria	1I7QU@117743,28NE3@1,2ZBGN@2,3ZR9V@59732,4NK1K@976	NA|NA|NA		
MAG.T21.45_01494	1229487.AMYW01000033_gene3413	2.5e-24	120.2	Flavobacteriia													Bacteria	1I8GX@117743,28VJ6@1,2ZHMM@2,4NMNU@976	NA|NA|NA		
MAG.T21.45_01496	1454007.JAUG01000020_gene1626	3.8e-236	824.3	Bacteria			3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	COG2865@1,COG2865@2	NA|NA|NA		
MAG.T21.45_01498	1094466.KQS_01325	1.6e-86	325.9	Flavobacteriia				ko:K07052					ko00000				Bacteria	1I24G@117743,4NPEG@976,COG1266@1,COG1266@2	NA|NA|NA	S	CAAX protease self-immunity
MAG.T21.45_01499	504487.JCM19302_3005	3.9e-67	261.9	Bacteria													Bacteria	COG2319@1,COG2319@2	NA|NA|NA	S	anaphase-promoting complex binding
MAG.T21.45_01500	761193.Runsl_4750	2e-149	535.4	Bacteroidetes				ko:K07148					ko00000				Bacteria	4NJDQ@976,COG2311@1,COG2311@2	NA|NA|NA	S	Protein of unknown function (DUF418)
MAG.T21.45_01501	1229487.AMYW01000024_gene375	2.5e-58	231.9	Flavobacteriia													Bacteria	1I3U0@117743,4NS67@976,COG0664@1,COG0664@2	NA|NA|NA	T	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MAG.T21.45_01502	1233950.IW22_01245	5.4e-154	550.8	Chryseobacterium													Bacteria	1HXN3@117743,3ZRAT@59732,4NGXR@976,COG1680@1,COG1680@2	NA|NA|NA	V	Beta-lactamase
MAG.T21.45_01503	1111730.ATTM01000002_gene966	1.1e-124	453.0	Flavobacteriia	xerC			ko:K04763					ko00000,ko03036				Bacteria	1IK4S@117743,4PM5A@976,COG0582@1,COG0582@2	NA|NA|NA	L	Phage integrase family
MAG.T21.45_01504	1111730.ATTM01000002_gene967	8.5e-154	550.1	Flavobacterium													Bacteria	1HYR8@117743,2NYJ5@237,4NHKP@976,COG0517@1,COG0517@2	NA|NA|NA	S	Putative transposase
MAG.T21.45_01505	1380600.AUYN01000009_gene2043	3.1e-10	72.0	Flavobacteriia													Bacteria	1I5US@117743,2DYGZ@1,32V5E@2,4NSGC@976	NA|NA|NA	S	Protein of unknown function (DUF3575)
MAG.T21.45_01506	1122179.KB890423_gene2300	1.1e-234	819.7	Sphingobacteriia			1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130		R06620	RC00066	ko00000,ko00001,ko01000				Bacteria	1IQUR@117747,4NFK0@976,COG4993@1,COG4993@2	NA|NA|NA	C	Pyrrolo-quinoline quinone
MAG.T21.45_01507	760192.Halhy_4717	1.6e-82	313.5	Sphingobacteriia													Bacteria	1IXHS@117747,4NEEP@976,COG1680@1,COG1680@2	NA|NA|NA	V	COG1680 Beta-lactamase class C and other penicillin binding
MAG.T21.45_01508	925409.KI911562_gene1393	2e-291	1008.1	Sphingobacteriia													Bacteria	1IPYF@117747,4NFG1@976,COG1554@1,COG1554@2	NA|NA|NA	G	Glycosyl hydrolase family 65 central catalytic domain
MAG.T21.45_01509	1178825.ALIH01000015_gene1875	4.5e-46	191.4	Flavobacteriia	yvaZ			ko:K06889					ko00000				Bacteria	1I1PF@117743,4NNCF@976,COG5658@1,COG5658@2	NA|NA|NA	S	SdpI/YhfL protein family
MAG.T21.45_01510	391598.FBBAL38_03745	7e-20	104.0	Flavobacteriia													Bacteria	1I9TI@117743,2E09A@1,32VWX@2,4NT9W@976	NA|NA|NA		
MAG.T21.45_01511	1121897.AUGO01000001_gene1300	8.5e-265	919.8	Flavobacterium				ko:K02014,ko:K16087					ko00000,ko02000	1.B.14,1.B.14.2			Bacteria	1HYJ3@117743,2NV1Z@237,4NFZY@976,COG1629@1,COG4771@2	NA|NA|NA	P	TonB dependent receptor
MAG.T21.45_01513	743722.Sph21_2573	5.7e-07	60.8	Sphingobacteriia													Bacteria	1ITZI@117747,2EGFG@1,33A7G@2,4P9MA@976	NA|NA|NA		
MAG.T21.45_01514	641524.ADICYQ_3314	6.3e-289	1000.0	Cytophagia				ko:K02014					ko00000,ko02000	1.B.14			Bacteria	47KSZ@768503,4NI3Y@976,COG4773@1,COG4773@2	NA|NA|NA	P	TonB dependent receptor
MAG.T21.45_01515	1506583.JQJY01000003_gene3702	3.4e-134	485.3	Flavobacterium													Bacteria	1ICKX@117743,2NSXJ@237,4NIWJ@976,COG3182@1,COG3182@2	NA|NA|NA	S	PepSY-associated TM region
MAG.T21.45_01516	760192.Halhy_3559	1.9e-204	718.8	Sphingobacteriia													Bacteria	1IWFX@117747,4NEZJ@976,COG3119@1,COG3119@2	NA|NA|NA	P	Sulfatase
MAG.T21.45_01517	471854.Dfer_4563	5.7e-239	833.6	Cytophagia			4.2.1.25	ko:K13875	ko00053,ko01100,map00053,map01100		R02522	RC00543	ko00000,ko00001,ko01000				Bacteria	47K3U@768503,4NEKY@976,COG0129@1,COG0129@2	NA|NA|NA	EG	Belongs to the IlvD Edd family
MAG.T21.45_01518	1122176.KB903576_gene4980	3.7e-193	681.4	Sphingobacteriia	yidK												Bacteria	1INRR@117747,4NEN8@976,COG0591@1,COG0591@2	NA|NA|NA	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MAG.T21.45_01520	1137281.D778_01222	1.9e-275	955.3	Flavobacteriia	mca			ko:K22136					ko00000				Bacteria	1HX7T@117743,4NE9K@976,COG2120@1,COG2120@2	NA|NA|NA	G	LmbE family
MAG.T21.45_01521	760192.Halhy_4486	3.6e-263	914.4	Bacteroidetes			5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995		ko00000,ko00001,ko00002,ko01000		GH13		Bacteria	4NFKK@976,COG1449@1,COG1449@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 57 family
MAG.T21.45_01522	700598.Niako_6810	5e-71	275.4	Bacteroidetes													Bacteria	4NDWS@976,COG4219@1,COG4219@2	NA|NA|NA	KT	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MAG.T21.45_01523	700598.Niako_6811	3.5e-37	161.0	Bacteroidetes													Bacteria	4NNVM@976,COG3682@1,COG3682@2	NA|NA|NA	K	transcriptional regulator
MAG.T21.45_01525	435590.BVU_3691	4.3e-18	97.4	Bacteroidaceae													Bacteria	293VH@1,2FYZ7@200643,2ZRAP@2,4AUAC@815,4PBF8@976	NA|NA|NA	S	STAS-like domain of unknown function (DUF4325)
MAG.T21.45_01526	485918.Cpin_2514	3.7e-51	208.0	Sphingobacteriia													Bacteria	1IUYT@117747,29TGV@1,30EQ4@2,4NQ0K@976	NA|NA|NA		
MAG.T21.45_01528	929562.Emtol_3641	1.8e-09	67.4	Cytophagia			3.5.1.88	ko:K01462					ko00000,ko01000				Bacteria	47PA5@768503,4NMRE@976,COG0242@1,COG0242@2	NA|NA|NA	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MAG.T21.45_01529	929703.KE386491_gene1885	9.2e-44	182.6	Cytophagia			3.5.1.88	ko:K01462					ko00000,ko01000				Bacteria	47PA5@768503,4NMRE@976,COG0242@1,COG0242@2	NA|NA|NA	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MAG.T21.45_01530	1122176.KB903532_gene2600	1.6e-41	176.8	Bacteroidetes													Bacteria	2E158@1,32WKA@2,4NZ2A@976	NA|NA|NA		
MAG.T21.45_01531	760192.Halhy_1562	1e-38	166.8	Sphingobacteriia				ko:K03088					ko00000,ko03021				Bacteria	1IT7R@117747,4NVCP@976,COG1595@1,COG1595@2	NA|NA|NA	K	Belongs to the sigma-70 factor family. ECF subfamily
MAG.T21.45_01532	760192.Halhy_1561	1.5e-29	136.0	Bacteroidetes													Bacteria	2AB14@1,339IP@2,4NZD5@976	NA|NA|NA		
MAG.T21.45_01533	313606.M23134_05108	8.4e-38	164.5	Cytophagia													Bacteria	47UMG@768503,4NPJT@976,COG3712@1,COG3712@2	NA|NA|NA	PT	Domain of unknown function (DUF4974)
MAG.T21.45_01534	760192.Halhy_1559	6.1e-142	511.9	Sphingobacteriia													Bacteria	1J0WJ@117747,4PM79@976,COG4206@1,COG4206@2	NA|NA|NA	H	TonB-dependent Receptor Plug Domain
MAG.T21.45_01535	760192.Halhy_1599	3.8e-100	371.3	Sphingobacteriia	lpxH		3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1IQAN@117747,4NFD8@976,COG2908@1,COG2908@2	NA|NA|NA	S	Phosphoesterase
MAG.T21.45_01537	760192.Halhy_1601	4.3e-95	354.8	Bacteroidetes				ko:K11312					ko00000				Bacteria	4PP19@976,COG1917@1,COG1917@2,COG4977@1,COG4977@2	NA|NA|NA	K	Cupin 2, conserved barrel domain protein
MAG.T21.45_01538	1121382.JQKG01000011_gene587	6e-43	181.8	Bacteria	ybjJ_3												Bacteria	COG2223@1,COG2223@2	NA|NA|NA	P	nitrite transmembrane transporter activity
MAG.T21.45_01540	760192.Halhy_4516	5.9e-102	378.6	Sphingobacteriia				ko:K02014					ko00000,ko02000	1.B.14			Bacteria	1ISVQ@117747,4NI2R@976,COG4206@1,COG4206@2	NA|NA|NA	H	Putative porin
MAG.T21.45_01541	760192.Halhy_4515	5.6e-120	437.2	Sphingobacteriia	fabI	GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1INTX@117747,4NEVE@976,COG0623@1,COG0623@2	NA|NA|NA	I	Enoyl- acyl-carrier-protein reductase NADH
MAG.T21.45_01542	760192.Halhy_4514	1.5e-167	596.3	Sphingobacteriia	recN			ko:K03631,ko:K07459					ko00000,ko03400				Bacteria	1IQ2B@117747,4NE3I@976,COG0497@1,COG0497@2	NA|NA|NA	L	May be involved in recombinational repair of damaged DNA
MAG.T21.45_01544	760192.Halhy_1387	5.7e-213	746.9	Sphingobacteriia	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPCY@117747,4NEQP@976,COG0114@1,COG0114@2	NA|NA|NA	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MAG.T21.45_01545	760192.Halhy_1388	6.2e-79	300.4	Sphingobacteriia	sodB		1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016				ko00000,ko00001,ko01000				Bacteria	1IQF9@117747,4NDZ4@976,COG0605@1,COG0605@2	NA|NA|NA	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MAG.T21.45_01546	760192.Halhy_1725	1.8e-27	129.0	Sphingobacteriia	rbpA												Bacteria	1ITMI@117747,4NT1J@976,COG0724@1,COG0724@2	NA|NA|NA	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MAG.T21.45_01547	760192.Halhy_1726	2.9e-212	745.3	Sphingobacteriia	pbpC		2.4.1.129	ko:K05367	ko00550,map00550				ko00000,ko00001,ko01000,ko01003,ko01011		GT51		Bacteria	1IP6N@117747,4NEG5@976,COG4953@1,COG4953@2	NA|NA|NA	M	Penicillin-binding Protein
MAG.T21.45_01548	760192.Halhy_4549	4.2e-150	538.5	Bacteroidetes													Bacteria	4NF45@976,COG0457@1,COG0457@2,COG2972@1,COG2972@2	NA|NA|NA	T	PFAM Signal transduction histidine kinase, internal region
MAG.T21.45_01550	760192.Halhy_4532	1.2e-95	356.3	Bacteroidetes				ko:K02477					ko00000,ko02022				Bacteria	4NNHE@976,COG3279@1,COG3279@2	NA|NA|NA	T	Response regulator of the LytR AlgR family
MAG.T21.45_01551	1122176.KB903531_gene3106	7.2e-39	166.8	Sphingobacteriia	doxX		1.6.99.3	ko:K03885,ko:K15977	ko00190,map00190				ko00000,ko00001,ko01000				Bacteria	1IZT9@117747,4NYPC@976,COG2259@1,COG2259@2	NA|NA|NA	S	SURF4 family
MAG.T21.45_01552	760192.Halhy_4530	3.2e-188	664.8	Sphingobacteriia	IV02_08645			ko:K07137					ko00000				Bacteria	1IQIE@117747,4NEUQ@976,COG2509@1,COG2509@2	NA|NA|NA	S	FAD-dependent dehydrogenase
MAG.T21.45_01554	760192.Halhy_4527	1.8e-122	446.0	Sphingobacteriia				ko:K07098					ko00000				Bacteria	1IPSC@117747,4NFCH@976,COG1408@1,COG1408@2	NA|NA|NA	S	DNA mismatch repair protein MutT
MAG.T21.45_01555	929562.Emtol_3917	1.6e-18	99.4	Cytophagia				ko:K09950					ko00000				Bacteria	47P8H@768503,4NMZ8@976,COG3495@1,COG3495@2	NA|NA|NA	S	Protein conserved in bacteria
MAG.T21.45_01556	760192.Halhy_1598	2.2e-281	974.5	Sphingobacteriia	lepA			ko:K03596	ko05134,map05134				ko00000,ko00001				Bacteria	1IQMU@117747,4NEJ9@976,COG0481@1,COG0481@2	NA|NA|NA	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MAG.T21.45_01557	760192.Halhy_4535	3.7e-26	125.6	Sphingobacteriia													Bacteria	1IZGS@117747,2DU3V@1,33NUP@2,4NYH7@976	NA|NA|NA		
MAG.T21.45_01558	1121896.JMLU01000009_gene1605	3.2e-109	401.7	Flavobacterium	sodA		1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016				ko00000,ko00001,ko01000				Bacteria	1I09P@117743,2NVJN@237,4NDZ4@976,COG0605@1,COG0605@2	NA|NA|NA	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MAG.T21.45_01559	929703.KE386491_gene3827	1.6e-23	115.9	Cytophagia													Bacteria	29WC5@1,30HXS@2,47SJP@768503,4NNWN@976	NA|NA|NA		
MAG.T21.45_01560	313595.P700755_003176	1.2e-69	270.0	Flavobacteriia													Bacteria	1I0S4@117743,4NGYF@976,COG0500@1,COG2226@2	NA|NA|NA	Q	Methyltransferase domain
MAG.T21.45_01561	1313421.JHBV01000016_gene5527	1.3e-70	273.9	Sphingobacteriia													Bacteria	1IWYM@117747,4NGRJ@976,COG3291@1,COG3291@2	NA|NA|NA	S	Pregnancy-associated plasma protein-A
MAG.T21.45_01562	929562.Emtol_3027	2.4e-129	469.2	Cytophagia			4.1.1.86	ko:K13745	ko00260,ko01120,map00260,map01120		R07650	RC00299	ko00000,ko00001,ko01000				Bacteria	47NKR@768503,4NFUP@976,COG0076@1,COG0076@2	NA|NA|NA	E	Pyridoxal-dependent decarboxylase conserved domain
MAG.T21.45_01563	929713.NIASO_00145	3e-192	677.9	Sphingobacteriia													Bacteria	1IWQT@117747,4NZSZ@976,COG0535@1,COG0535@2	NA|NA|NA	S	Elongator protein 3, MiaB family, Radical SAM
MAG.T21.45_01564	760192.Halhy_5962	2.8e-172	612.1	Sphingobacteriia	sppA	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564		ko:K04773					ko00000,ko01000,ko01002				Bacteria	1IP6H@117747,4NES1@976,COG0616@1,COG0616@2	NA|NA|NA	OU	signal peptide peptidase SppA, 67K type
MAG.T21.45_01565	760192.Halhy_0808	4.2e-104	384.4	Sphingobacteriia	soj			ko:K03496					ko00000,ko03036,ko04812				Bacteria	1IQ5V@117747,4NFEX@976,COG1192@1,COG1192@2	NA|NA|NA	D	CobQ CobB MinD ParA nucleotide binding domain
MAG.T21.45_01566	760192.Halhy_0807	8.8e-82	310.5	Sphingobacteriia	noc			ko:K03497					ko00000,ko03000,ko03036,ko04812				Bacteria	1IPCV@117747,4NFZ9@976,COG1475@1,COG1475@2	NA|NA|NA	K	Belongs to the ParB family
MAG.T21.45_01567	760192.Halhy_0806	1.4e-38	166.4	Sphingobacteriia													Bacteria	1ITDS@117747,28PR3@1,2ZCD0@2,4NMAF@976	NA|NA|NA		
MAG.T21.45_01568	984262.SGRA_3478	4e-131	474.6	Sphingobacteriia		GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008076,GO:0008150,GO:0008152,GO:0009117,GO:0009898,GO:0009987,GO:0010959,GO:0012505,GO:0012506,GO:0015459,GO:0016020,GO:0016021,GO:0016192,GO:0016247,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019637,GO:0019897,GO:0019898,GO:0030141,GO:0030424,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031226,GO:0031234,GO:0031410,GO:0031982,GO:0032879,GO:0032880,GO:0032940,GO:0032991,GO:0033267,GO:0034641,GO:0034702,GO:0034703,GO:0034705,GO:0034762,GO:0034765,GO:0035579,GO:0036230,GO:0042119,GO:0042581,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043266,GO:0043269,GO:0043299,GO:0043312,GO:0044224,GO:0044237,GO:0044238,GO:0044281,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046496,GO:0046903,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051179,GO:0051186,GO:0051234,GO:0055086,GO:0055114,GO:0060341,GO:0065007,GO:0065009,GO:0070820,GO:0070821,GO:0070995,GO:0071704,GO:0071944,GO:0072524,GO:0097458,GO:0097708,GO:0098552,GO:0098562,GO:0098588,GO:0098772,GO:0098796,GO:0098797,GO:0098805,GO:0099106,GO:0099503,GO:0120025,GO:0120038,GO:1901360,GO:1901379,GO:1901564,GO:1902495,GO:1903827,GO:1904062,GO:1990031,GO:1990351,GO:2000008											Bacteria	1IQIA@117747,4NFCN@976,COG0667@1,COG0667@2	NA|NA|NA	C	potassium channel beta subunit
MAG.T21.45_01569	1122176.KB903619_gene5409	1.5e-118	433.0	Sphingobacteriia	ilvE		2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007			iAF987.Gmet_2853,iYO844.BSU38550	Bacteria	1IP2X@117747,4NEJY@976,COG0115@1,COG0115@2	NA|NA|NA	EH	Branched-chain amino acid aminotransferase
MAG.T21.45_01570	760192.Halhy_4740	3.5e-87	327.8	Sphingobacteriia	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02355					ko00000,ko03012,ko03029				Bacteria	1INUJ@117747,4NE9X@976,COG0480@1,COG0480@2	NA|NA|NA	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MAG.T21.45_01571	760192.Halhy_4741	1.3e-48	198.7	Sphingobacteriia	rpsJ	GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141		ko:K02946	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1ISQN@117747,4NQ65@976,COG0051@1,COG0051@2	NA|NA|NA	J	Involved in the binding of tRNA to the ribosomes
MAG.T21.45_01572	760192.Halhy_4742	5.9e-85	320.5	Sphingobacteriia	rplC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234		ko:K02906	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IPGZ@117747,4NEAN@976,COG0087@1,COG0087@2	NA|NA|NA	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MAG.T21.45_01573	760192.Halhy_4743	4.4e-72	277.7	Sphingobacteriia	rplD	GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141		ko:K02926,ko:K16193	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IRTU@117747,4NEWZ@976,COG0088@1,COG0088@2	NA|NA|NA	J	Forms part of the polypeptide exit tunnel
MAG.T21.45_01574	1122176.KB903535_gene1951	5.7e-21	106.7	Sphingobacteriia	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02892	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1ITE2@117747,4NS7H@976,COG0089@1,COG0089@2	NA|NA|NA	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MAG.T21.45_01575	1122176.KB903535_gene1950	1.1e-118	433.0	Sphingobacteriia	rplB	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02886	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1INT6@117747,4NE8G@976,COG0090@1,COG0090@2	NA|NA|NA	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MAG.T21.45_01576	760192.Halhy_4746	8e-39	166.0	Sphingobacteriia	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02965	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1ISXF@117747,4NQ8T@976,COG0185@1,COG0185@2	NA|NA|NA	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MAG.T21.45_01577	760192.Halhy_4747	9.4e-41	172.9	Sphingobacteriia	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02890	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1ISMN@117747,4NQ8E@976,COG0091@1,COG0091@2	NA|NA|NA	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MAG.T21.45_01578	760192.Halhy_4748	1.2e-101	376.3	Sphingobacteriia	rpsC	GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02982	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IPKE@117747,4NE9F@976,COG0092@1,COG0092@2	NA|NA|NA	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MAG.T21.45_01579	1122179.KB890458_gene658	6.1e-54	216.9	Sphingobacteriia	rplP	GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02878	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IRSN@117747,4NM87@976,COG0197@1,COG0197@2	NA|NA|NA	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MAG.T21.45_01580	1122176.KB903535_gene1945	5.1e-14	83.6	Bacteria	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02904	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	COG0255@1,COG0255@2	NA|NA|NA	J	Belongs to the universal ribosomal protein uL29 family
MAG.T21.45_01581	485918.Cpin_1624	2.5e-29	134.4	Sphingobacteriia	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02961	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IT9T@117747,4NSB2@976,COG0186@1,COG0186@2	NA|NA|NA	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MAG.T21.45_01582	760192.Halhy_4752	5.7e-56	223.4	Sphingobacteriia	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02874	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1ISEA@117747,4NNM6@976,COG0093@1,COG0093@2	NA|NA|NA	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MAG.T21.45_01583	1122176.KB903535_gene1942	4e-30	137.5	Sphingobacteriia	rplX	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02895	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1ISXS@117747,4NSTI@976,COG0198@1,COG0198@2	NA|NA|NA	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MAG.T21.45_01584	760192.Halhy_4754	4.4e-79	300.8	Sphingobacteriia	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02931	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IPX4@117747,4NEGY@976,COG0094@1,COG0094@2	NA|NA|NA	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MAG.T21.45_01585	984262.SGRA_1832	7e-35	152.9	Sphingobacteriia	rpsN	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02954	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IY7E@117747,4NQ6N@976,COG0199@1,COG0199@2	NA|NA|NA	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MAG.T21.45_01586	760192.Halhy_4756	4.9e-56	223.8	Sphingobacteriia	rpsH	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904		ko:K02994	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IS0B@117747,4NNFW@976,COG0096@1,COG0096@2	NA|NA|NA	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MAG.T21.45_01587	760192.Halhy_4757	4.3e-71	274.2	Sphingobacteriia	rplF	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02933	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IRC9@117747,4NGJM@976,COG0097@1,COG0097@2	NA|NA|NA	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MAG.T21.45_01588	1121899.Q764_08165	6.2e-31	140.2	Flavobacterium	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02881	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1I2S3@117743,2NW83@237,4NQAS@976,COG0256@1,COG0256@2	NA|NA|NA	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MAG.T21.45_01589	760192.Halhy_4759	6e-75	287.0	Sphingobacteriia	rpsE	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904		ko:K02988	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IQ9B@117747,4NG1Z@976,COG0098@1,COG0098@2	NA|NA|NA	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MAG.T21.45_01590	1122176.KB903535_gene1935	5.1e-13	79.7	Sphingobacteriia	rpmD	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02907	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IUA3@117747,4NUXV@976,COG1841@1,COG1841@2	NA|NA|NA	J	Ribosomal protein L30
MAG.T21.45_01591	760192.Halhy_4761	8.6e-38	163.3	Sphingobacteriia	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904		ko:K02876	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IRSX@117747,4NNFQ@976,COG0200@1,COG0200@2	NA|NA|NA	J	binds to the 23S rRNA
MAG.T21.45_01592	760192.Halhy_4762	2.6e-173	615.1	Sphingobacteriia	secY	GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680		ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5			Bacteria	1IPEC@117747,4NEPU@976,COG0201@1,COG0201@2	NA|NA|NA	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MAG.T21.45_01593	760192.Halhy_4763	1.2e-82	313.2	Sphingobacteriia	map		3.4.11.18	ko:K01265					ko00000,ko01000,ko01002				Bacteria	1IP59@117747,4NERQ@976,COG0024@1,COG0024@2	NA|NA|NA	J	Methionine aminopeptidase
MAG.T21.45_01594	760192.Halhy_4764	1.4e-30	138.3	Sphingobacteriia	infA	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065		ko:K02518					ko00000,ko03012				Bacteria	1IT95@117747,4NS6S@976,COG0361@1,COG0361@2	NA|NA|NA	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MAG.T21.45_01595	760192.Halhy_4765	7.2e-46	189.9	Sphingobacteriia	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02952	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1ISH0@117747,4NNGZ@976,COG0099@1,COG0099@2	NA|NA|NA	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MAG.T21.45_01596	760192.Halhy_4766	2.9e-53	214.5	Sphingobacteriia	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02948	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1ISSN@117747,4NNHA@976,COG0100@1,COG0100@2	NA|NA|NA	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MAG.T21.45_01597	760192.Halhy_4767	5.6e-80	303.9	Sphingobacteriia	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112		ko:K02986	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1INSQ@117747,4NEMZ@976,COG0522@1,COG0522@2	NA|NA|NA	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MAG.T21.45_01598	760192.Halhy_4768	2.8e-161	574.7	Sphingobacteriia	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400				Bacteria	1IQ3D@117747,4NE8W@976,COG0202@1,COG0202@2	NA|NA|NA	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAG.T21.45_01599	1380384.JADN01000003_gene571	3.4e-46	191.4	Flavobacteriia	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904		ko:K02879	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1I1B5@117743,4NNW0@976,COG0203@1,COG0203@2	NA|NA|NA	J	ribosomal protein l17
MAG.T21.45_01600	760192.Halhy_4776	2.4e-145	521.9	Sphingobacteriia	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv1383	Bacteria	1IPSN@117747,4NEQI@976,COG0505@1,COG0505@2	NA|NA|NA	F	Belongs to the CarA family
MAG.T21.45_01601	760192.Halhy_4777	3.9e-192	677.6	Sphingobacteriia	eno	GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147				Bacteria	1IP9V@117747,4NF5M@976,COG0148@1,COG0148@2	NA|NA|NA	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MAG.T21.45_01602	760192.Halhy_4778	9.6e-17	92.8	Sphingobacteriia	divIC			ko:K05589,ko:K12065,ko:K13052					ko00000,ko02044,ko03036	3.A.7.11.1			Bacteria	1IU1T@117747,4NURQ@976,COG2919@1,COG2919@2	NA|NA|NA	D	Septum formation initiator
MAG.T21.45_01603	1122176.KB903532_gene2576	2.4e-137	495.0	Sphingobacteriia	sucD	GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009361,GO:0009987,GO:0016310,GO:0019538,GO:0032991,GO:0036211,GO:0040011,GO:0042709,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0046777,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071973,GO:0097588,GO:1901564,GO:1902494	6.2.1.5	ko:K01902,ko:K02381	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000			iE2348C_1286.E2348C_0608	Bacteria	1INZ1@117747,4NE6B@976,COG0074@1,COG0074@2	NA|NA|NA	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MAG.T21.45_01604	388413.ALPR1_10740	1.2e-109	403.7	Cytophagia													Bacteria	47M2K@768503,4NF9W@976,COG0671@1,COG0671@2	NA|NA|NA	I	PFAM Phosphatidic acid phosphatase type 2 haloperoxidase
MAG.T21.45_01605	760192.Halhy_1356	2.4e-172	612.5	Sphingobacteriia													Bacteria	1IPCG@117747,4NE6G@976,COG0457@1,COG0457@2,COG0823@1,COG0823@2,COG2885@1,COG2885@2	NA|NA|NA	MU	Belongs to the ompA family
MAG.T21.45_01607	202952.BBLI01000034_gene2373	3e-57	229.2	Moraxellaceae													Bacteria	1R4AR@1224,1RMPA@1236,28ISW@1,2Z8RZ@2,3NKVA@468	NA|NA|NA		
MAG.T21.45_01608	1250278.JQNQ01000001_gene1688	1.6e-12	79.3	Flavobacteriia													Bacteria	1I2KT@117743,4NQ0S@976,COG2207@1,COG2207@2	NA|NA|NA	K	Helix-turn-helix domain
MAG.T21.45_01609	1189612.A33Q_1093	2e-96	359.0	Cytophagia	MA20_14845		4.2.1.141	ko:K14259	ko00040,map00040		R09186	RC00429	ko00000,ko00001,ko01000				Bacteria	47MQU@768503,4NGTH@976,COG3970@1,COG3970@2	NA|NA|NA	S	PFAM fumarylacetoacetate (FAA) hydrolase
MAG.T21.45_01610	1250232.JQNJ01000001_gene2254	2.3e-149	535.8	Flavobacteriia	aldH		1.2.1.26,1.2.1.4	ko:K13877,ko:K14519	ko00040,ko00053,ko00930,ko01100,ko01120,ko01220,map00040,map00053,map00930,map01100,map01120,map01220		R00264,R05099	RC00080	ko00000,ko00001,ko01000				Bacteria	1HX1F@117743,4NEKG@976,COG1012@1,COG1012@2	NA|NA|NA	C	Aldehyde
MAG.T21.45_01611	1185876.BN8_04274	8.7e-35	153.7	Cytophagia				ko:K03088					ko00000,ko03021				Bacteria	47QM1@768503,4NRG1@976,COG1595@1,COG1595@2	NA|NA|NA	K	Sigma-70, region 4
MAG.T21.45_01612	945713.IALB_0846	1e-09	71.6	Bacteria													Bacteria	COG1520@1,COG1520@2,COG1572@1,COG1572@2,COG3291@1,COG3291@2,COG4733@1,COG4733@2	NA|NA|NA	NU	bacterial-type flagellum-dependent cell motility
MAG.T21.45_01613	700598.Niako_2244	4.6e-34	152.1	Sphingobacteriia				ko:K07165					ko00000				Bacteria	1ISMZ@117747,4NNSK@976,COG3712@1,COG3712@2	NA|NA|NA	PT	PFAM FecR protein
MAG.T21.45_01614	1123008.KB905718_gene3610	9.6e-222	777.3	Porphyromonadaceae													Bacteria	22X7J@171551,2FM2D@200643,4NDXS@976,COG1629@1,COG1629@2	NA|NA|NA	P	TonB dependent receptor
MAG.T21.45_01615	1123008.KB905718_gene3611	3.1e-93	349.4	Porphyromonadaceae	tdk		2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100		R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	22XKV@171551,2FMKG@200643,4NHCM@976,COG1435@1,COG1435@2	NA|NA|NA	F	Pfam:SusD
MAG.T21.45_01618	1279009.ADICEAN_02308	1.2e-87	330.9	Cytophagia													Bacteria	47UAR@768503,4NI9V@976,COG1649@1,COG1649@2	NA|NA|NA	E	protein conserved in bacteria
MAG.T21.45_01619	1443665.JACA01000013_gene4286	2.5e-46	192.6	Aquimarina	modC		3.6.3.29,3.6.3.30	ko:K02010,ko:K02017	ko02010,map02010	M00189,M00190			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.8			Bacteria	1I0DW@117743,2YHZB@290174,4NK56@976,COG3842@1,COG3842@2	NA|NA|NA	E	ATPases associated with a variety of cellular activities
MAG.T21.45_01620	1158338.JNLJ01000005_gene1441	3.1e-63	248.4	Aquificae	modB			ko:K02018,ko:K15496	ko02010,map02010	M00189,M00423			ko00000,ko00001,ko00002,ko02000	3.A.1.6.5,3.A.1.8			Bacteria	2G44N@200783,COG4149@1,COG4149@2	NA|NA|NA	P	TIGRFAM molybdate ABC transporter, inner membrane subunit
MAG.T21.45_01621	1158338.JNLJ01000005_gene1439	6.7e-46	191.0	Bacteria	modA			ko:K02020	ko02010,map02010	M00189			ko00000,ko00001,ko00002,ko02000	3.A.1.8			Bacteria	COG0725@1,COG0725@2	NA|NA|NA	P	tungstate binding
MAG.T21.45_01622	1313421.JHBV01000024_gene5027	5.9e-66	257.3	Sphingobacteriia	cysC	GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564	1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4	ko:K00390,ko:K00860,ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R02021,R04928,R04929	RC00002,RC00007,RC00078,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000				Bacteria	1ITQ0@117747,4NGCU@976,COG0529@1,COG0529@2	NA|NA|NA	P	Catalyzes the synthesis of activated sulfate
MAG.T21.45_01623	760192.Halhy_2967	8.5e-133	479.9	Sphingobacteriia	cysD	GO:0000103,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:1902494,GO:1902503,GO:1990234	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000				Bacteria	1INWY@117747,4NEPD@976,COG0175@1,COG0175@2	NA|NA|NA	EH	PFAM Phosphoadenosine phosphosulfate reductase
MAG.T21.45_01624	760192.Halhy_2966	2.6e-196	691.4	Sphingobacteriia	cysN	GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQ1H@117747,4NETI@976,COG2895@1,COG2895@2	NA|NA|NA	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
MAG.T21.45_01625	1121904.ARBP01000011_gene1559	5.1e-145	521.2	Cytophagia			3.2.1.40	ko:K05989					ko00000,ko01000				Bacteria	47NG8@768503,4NHH7@976,COG3119@1,COG3119@2,COG3408@1,COG3408@2	NA|NA|NA	GP	Domain of unknown function (DUF4976)
MAG.T21.45_01627	273121.WS1135	1.3e-85	323.2	Epsilonproteobacteria													Bacteria	1R51A@1224,2YNQ6@29547,42PGS@68525,COG1502@1,COG1502@2	NA|NA|NA	I	ORF6N domain
MAG.T21.45_01628	1239962.C943_03747	9.4e-36	156.4	Cytophagia				ko:K04750					ko00000				Bacteria	47XP0@768503,4NSNJ@976,COG2764@1,COG2764@2	NA|NA|NA	S	3-demethylubiquinone-9 3-methyltransferase
MAG.T21.45_01629	760192.Halhy_0880	8.2e-208	729.9	Bacteroidetes			4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230		R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000				Bacteria	4NJF4@976,COG1760@1,COG1760@2	NA|NA|NA	E	Serine dehydratase alpha chain
MAG.T21.45_01630	761193.Runsl_4230	2.2e-114	418.7	Cytophagia	XK27_00825			ko:K07090					ko00000				Bacteria	47UR9@768503,4NK54@976,COG0730@1,COG0730@2	NA|NA|NA	S	Sulfite exporter TauE/SafE
MAG.T21.45_01631	925409.KI911562_gene2711	1.1e-119	436.4	Sphingobacteriia	dapA2		3.5.4.22,4.3.3.7	ko:K01714,ko:K21062	ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02280,R10147	RC00679,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQRX@117747,4NF2Z@976,COG0329@1,COG0329@2	NA|NA|NA	EM	Belongs to the DapA family
MAG.T21.45_01632	1123057.P872_02175	2.4e-159	568.9	Cytophagia	tolB2												Bacteria	47KMG@768503,4NG4S@976,COG0823@1,COG0823@2	NA|NA|NA	U	WD40-like Beta Propeller Repeat
MAG.T21.45_01633	760192.Halhy_4098	9.9e-182	643.3	Bacteria													Bacteria	COG1672@1,COG1672@2	NA|NA|NA		
MAG.T21.45_01634	1313421.JHBV01000025_gene1046	2.4e-36	158.3	Sphingobacteriia	FolA												Bacteria	1IYRJ@117747,4NN8Y@976,COG0262@1,COG0262@2	NA|NA|NA	H	RibD C-terminal domain
MAG.T21.45_01635	714943.Mucpa_5980	8.5e-109	399.8	Sphingobacteriia				ko:K07043					ko00000				Bacteria	1IUYI@117747,4NIY4@976,COG1451@1,COG1451@2	NA|NA|NA	S	Protein of unknown function DUF45
MAG.T21.45_01636	714943.Mucpa_5981	0.0	1835.1	Sphingobacteriia	hsdR		3.1.21.3	ko:K01153					ko00000,ko01000,ko02048				Bacteria	1IVJ6@117747,4NFJ8@976,COG0610@1,COG0610@2	NA|NA|NA	F	Subunit R is required for both nuclease and ATPase activities, but not for modification
MAG.T21.45_01638	1305737.JAFX01000001_gene1423	1.6e-270	938.3	Bacteroidetes			3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	4NFVX@976,COG2865@1,COG2865@2	NA|NA|NA	K	transcriptional regulator containing an HTH domain and an
MAG.T21.45_01639	755732.Fluta_3970	4.9e-66	258.5	Flavobacteriia													Bacteria	1I5VW@117743,4NPN9@976,COG0515@1,COG0515@2	NA|NA|NA	KLT	PFAM Protein kinase domain
MAG.T21.45_01640	509635.N824_24985	3.3e-31	141.4	Bacteroidetes													Bacteria	2ASWM@1,32ZGF@2,4P897@976	NA|NA|NA	S	Protein of unknown function (DUF3010)
MAG.T21.45_01642	1313421.JHBV01000045_gene208	8.5e-77	294.3	Bacteroidetes	hsdS		3.1.21.3	ko:K01154					ko00000,ko01000,ko02048				Bacteria	4NNKR@976,COG0732@1,COG0732@2	NA|NA|NA	V	Type I restriction modification DNA specificity domain
MAG.T21.45_01643	36874.HQ34_07950	1.5e-115	422.5	Porphyromonadaceae	dinD	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496		ko:K07741,ko:K14623					ko00000,ko03400				Bacteria	22YCF@171551,2FNEB@200643,4NJ37@976,COG3645@1,COG3645@2	NA|NA|NA	S	BRO family, N-terminal domain
MAG.T21.45_01644	714943.Mucpa_5984	9.2e-268	929.1	Sphingobacteriia	hsdM		2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	1IQM3@117747,4NG0E@976,COG0286@1,COG0286@2	NA|NA|NA	V	COG0286 Type I restriction-modification system methyltransferase subunit
MAG.T21.45_01645	1158294.JOMI01000007_gene537	1.4e-33	149.1	Bacteroidia													Bacteria	2CCSR@1,2FU2H@200643,32RWC@2,4NSDM@976	NA|NA|NA	S	tigr02436
MAG.T21.45_01647	714943.Mucpa_5985	3.7e-70	271.2	Sphingobacteriia	hsdS2		2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	1IYQ8@117747,4NTFY@976,COG0732@1,COG0732@2	NA|NA|NA	V	Type I restriction modification DNA specificity domain
MAG.T21.45_01649	553174.HMPREF0659_A6259	1.1e-15	89.7	Bacteroidia			3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	2G2D4@200643,4NPC1@976,COG2865@1,COG2865@2	NA|NA|NA	K	Putative ATP-dependent DNA helicase recG C-terminal
MAG.T21.45_01650	694427.Palpr_0422	2.1e-84	318.9	Porphyromonadaceae													Bacteria	22WHD@171551,2FPNW@200643,4NNCZ@976,COG1409@1,COG1409@2	NA|NA|NA	S	Calcineurin-like phosphoesterase
MAG.T21.45_01651	1492738.FEM21_14570	2.2e-49	203.0	Flavobacterium				ko:K07011					ko00000				Bacteria	1IBUM@117743,2NT57@237,4NH8F@976,COG3206@1,COG3206@2	NA|NA|NA	M	Lipopolysaccharide biosynthesis protein
MAG.T21.45_01652	1122179.KB890424_gene3578	3.4e-108	399.8	Sphingobacteriia				ko:K01991	ko02026,map02026				ko00000,ko00001,ko02000	1.B.18			Bacteria	1IPNG@117747,4NEXJ@976,COG1596@1,COG1596@2	NA|NA|NA	M	export protein
MAG.T21.45_01653	509635.N824_13655	1.6e-141	510.0	Sphingobacteriia	capD		4.2.1.115,4.2.1.46	ko:K01710,ko:K15894	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	M00793	R06513,R09697	RC00402,RC02609	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPH4@117747,4NERY@976,COG1086@1,COG1086@2	NA|NA|NA	GM	Polysaccharide biosynthesis protein
MAG.T21.45_01655	760192.Halhy_5177	4.2e-41	174.1	Sphingobacteriia				ko:K04749					ko00000,ko03021				Bacteria	1ISU9@117747,4NTPB@976,COG1366@1,COG1366@2	NA|NA|NA	T	transporter antisigma-factor antagonist STAS
MAG.T21.45_01656	760192.Halhy_5176	0.0	1371.3	Sphingobacteriia	clpC			ko:K03696	ko01100,map01100				ko00000,ko03110				Bacteria	1IPYI@117747,4NE1J@976,COG0542@1,COG0542@2	NA|NA|NA	O	with chaperone activity ATP-binding subunit
MAG.T21.45_01657	760192.Halhy_5174	4.9e-81	307.4	Sphingobacteriia	infC	GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767		ko:K02520					ko00000,ko03012,ko03029				Bacteria	1IRGC@117747,4NIZ5@976,COG0290@1,COG0290@2	NA|NA|NA	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MAG.T21.45_01658	760192.Halhy_5158	4.3e-18	96.7	Sphingobacteriia	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904		ko:K02916	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IU0V@117747,4NUVR@976,COG0291@1,COG0291@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL35 family
MAG.T21.45_01659	760192.Halhy_5157	2.5e-37	161.4	Sphingobacteriia	rplT	GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141		ko:K02887	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1ISA4@117747,4NNKU@976,COG0292@1,COG0292@2	NA|NA|NA	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MAG.T21.45_01660	760192.Halhy_5156	1.4e-74	287.3	Bacteria				ko:K17733					ko00000,ko01000,ko01002,ko01011				Bacteria	COG3409@1,COG3409@2	NA|NA|NA	M	Peptidoglycan-binding domain 1 protein
MAG.T21.45_01661	926556.Echvi_3257	1.8e-13	84.0	Cytophagia													Bacteria	47MZH@768503,4NIJV@976,COG2207@1,COG2207@2	NA|NA|NA	K	helix_turn_helix, arabinose operon control protein
MAG.T21.45_01662	1223410.KN050846_gene1117	1.6e-279	971.5	Flavobacteriia													Bacteria	1IJ7S@117743,4PKBQ@976,COG1361@1,COG1361@2,COG3170@1,COG3170@2,COG3209@1,COG3209@2,COG3210@1,COG3210@2,COG5184@1,COG5184@2	NA|NA|NA	M	SPTR CHU large protein
MAG.T21.45_01663	1185876.BN8_00772	1.6e-90	341.3	Cytophagia				ko:K20276	ko02024,map02024				ko00000,ko00001				Bacteria	47MNQ@768503,4NDZC@976,COG3209@1,COG3209@2,COG3291@1,COG3291@2	NA|NA|NA	O	SprB repeat
MAG.T21.45_01664	1120966.AUBU01000016_gene3073	1.1e-16	94.7	Bacteroidetes													Bacteria	2AA00@1,30Z8H@2,4NPZI@976	NA|NA|NA		
MAG.T21.45_01665	1122176.KB903531_gene3050	3.7e-84	318.2	Sphingobacteriia	crt		4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200		R03026	RC00831	ko00000,ko00001,ko01000				Bacteria	1INKY@117747,4NFEM@976,COG1024@1,COG1024@2	NA|NA|NA	I	Belongs to the enoyl-CoA hydratase isomerase family
MAG.T21.45_01666	471854.Dfer_1586	1.9e-29	136.0	Bacteroidetes				ko:K03088					ko00000,ko03021				Bacteria	4NSRK@976,COG1595@1,COG1595@2	NA|NA|NA	K	RNA polymerase, sigma factor
MAG.T21.45_01667	509635.N824_00990	2.2e-61	243.0	Sphingobacteriia													Bacteria	1IUSA@117747,4NZSF@976,COG3712@1,COG3712@2	NA|NA|NA	PT	Domain of unknown function (DUF4974)
MAG.T21.45_01668	485917.Phep_0058	5.5e-223	781.6	Sphingobacteriia													Bacteria	1IV46@117747,4NDXS@976,COG1629@1,COG1629@2	NA|NA|NA	P	TonB-linked outer membrane protein, SusC RagA family
MAG.T21.45_01669	485917.Phep_0057	1.4e-76	293.9	Sphingobacteriia				ko:K07502,ko:K19804,ko:K21572					ko00000,ko02000	8.A.46.1,8.A.46.3			Bacteria	1IW33@117747,4NGAI@976,COG2956@1,COG2956@2	NA|NA|NA	G	RagB SusD domain protein
MAG.T21.45_01670	172045.KS04_22190	4.3e-44	185.7	Flavobacteriia													Bacteria	1HY1W@117743,4NEX3@976,COG0526@1,COG0526@2	NA|NA|NA	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MAG.T21.45_01671	760192.Halhy_4552	5.5e-19	102.1	Bacteroidetes													Bacteria	4NJ6B@976,COG5263@1,COG5263@2	NA|NA|NA	KLT	PFAM KWG Leptospira
MAG.T21.45_01673	1123057.P872_14630	7.1e-229	800.0	Cytophagia	lysS		6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	47M2W@768503,4NDZN@976,COG1190@1,COG1190@2	NA|NA|NA	J	Belongs to the class-II aminoacyl-tRNA synthetase family
MAG.T21.45_01674	1122176.KB903551_gene4209	1.1e-108	399.8	Sphingobacteriia	acuC												Bacteria	1IQR5@117747,4NF3X@976,COG0123@1,COG0123@2	NA|NA|NA	BQ	PFAM Histone deacetylase
MAG.T21.45_01675	1048983.EL17_21025	2.2e-97	362.5	Cytophagia													Bacteria	47K3M@768503,4NJT2@976,COG5464@1,COG5464@2	NA|NA|NA	S	PD-(D/E)XK nuclease family transposase
MAG.T21.45_01676	1122179.KB890431_gene4241	8.9e-210	736.5	Bacteroidetes													Bacteria	4NK1Q@976,COG4805@1,COG4805@2	NA|NA|NA	S	Protein conserved in bacteria
MAG.T21.45_01677	1122176.KB903598_gene4759	9.6e-41	172.9	Sphingobacteriia													Bacteria	1IU9P@117747,2ASD9@1,31HSR@2,4NQ71@976	NA|NA|NA	S	SMART PUR-alpha beta gamma DNA RNA-binding
MAG.T21.45_01678	760192.Halhy_1230	1.2e-158	567.0	Sphingobacteriia	xynX5												Bacteria	1IRAV@117747,4NER3@976,COG2304@1,COG2304@2	NA|NA|NA	S	oxidoreductase activity
MAG.T21.45_01679	760192.Halhy_1231	1.4e-184	652.5	Sphingobacteriia													Bacteria	1IPF3@117747,2CD20@1,2Z7SQ@2,4NEQ1@976	NA|NA|NA		
MAG.T21.45_01680	760192.Halhy_1233	7.2e-118	430.6	Sphingobacteriia	degP		1.3.1.74	ko:K08070					ko00000,ko01000				Bacteria	1INQ7@117747,4NFCS@976,COG0265@1,COG0265@2	NA|NA|NA	O	COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain
MAG.T21.45_01681	1034807.FBFL15_0962	1.1e-37	164.1	Bacteroidetes													Bacteria	2DZSH@1,32VHS@2,4NYRA@976	NA|NA|NA	S	to other proteins from the same organism
MAG.T21.45_01683	1086011.HJ01_03555	1.9e-93	349.4	Flavobacterium				ko:K07486					ko00000				Bacteria	1HXB1@117743,2NV7J@237,4NKDC@976,COG3547@1,COG3547@2	NA|NA|NA	L	Transposase IS116/IS110/IS902 family
MAG.T21.45_01684	649349.Lbys_0782	5.5e-180	637.1	Cytophagia				ko:K07133					ko00000				Bacteria	47MF2@768503,4NE39@976,COG1373@1,COG1373@2	NA|NA|NA	S	Domain of unknown function (DUF4143)
MAG.T21.45_01685	746697.Aeqsu_3101	2.7e-18	98.2	Flavobacteriia													Bacteria	1I48J@117743,4NX0K@976,COG1476@1,COG1476@2	NA|NA|NA	K	Helix-turn-helix XRE-family like proteins
MAG.T21.45_01686	1358423.N180_04900	1.6e-169	602.4	Sphingobacteriia			2.7.11.1	ko:K07154					ko00000,ko01000,ko01001,ko02048				Bacteria	1IUS6@117747,4NFYY@976,COG3550@1,COG3550@2	NA|NA|NA	S	Pfam:HipA_N
MAG.T21.45_01687	1123278.KB893589_gene508	7.1e-210	736.5	Cytophagia	hsdM		2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	47MHT@768503,4NG0E@976,COG0286@1,COG0286@2	NA|NA|NA	V	type I restriction-modification
MAG.T21.45_01688	1416760.AYMS01000039_gene1384	1.5e-109	402.9	Flavobacteriia													Bacteria	1I60D@117743,4NJJG@976,COG2110@1,COG2110@2	NA|NA|NA	S	Macro domain
MAG.T21.45_01690	1416760.AYMS01000039_gene1383	2.8e-07	60.8	Flavobacteriia			4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000				Bacteria	1I6AZ@117743,4NUSI@976,COG4948@1,COG4948@2	NA|NA|NA	M	Domain of unknown function (DUF4433)
MAG.T21.45_01691	1416760.AYMS01000039_gene1383	1.8e-13	81.6	Flavobacteriia			4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000				Bacteria	1I6AZ@117743,4NUSI@976,COG4948@1,COG4948@2	NA|NA|NA	M	Domain of unknown function (DUF4433)
MAG.T21.45_01692	1347392.CCEZ01000004_gene705	8.9e-69	267.7	Clostridia	hsdS		3.1.21.3	ko:K01154					ko00000,ko01000,ko02048				Bacteria	1TP5N@1239,24DRR@186801,COG0732@1,COG0732@2	NA|NA|NA	V	Type I restriction
MAG.T21.45_01693	883096.HMPREF9699_01720	2e-133	482.3	Flavobacteriia													Bacteria	1HZKE@117743,4NGY8@976,COG4804@1,COG4804@2	NA|NA|NA	S	Protein of unknown function (DUF1016)
MAG.T21.45_01694	1123278.KB893598_gene2678	0.0	1682.5	Cytophagia	hsdR		3.1.21.3	ko:K01153					ko00000,ko01000,ko02048				Bacteria	47K4E@768503,4NFJ8@976,COG0610@1,COG0610@2	NA|NA|NA	V	Subunit R is required for both nuclease and ATPase activities, but not for modification
MAG.T21.45_01695	1122226.AUHX01000022_gene2001	2.3e-21	107.5	Flavobacteriia				ko:K07467					ko00000				Bacteria	1I50U@117743,4PKTU@976,COG1476@1,COG1476@2	NA|NA|NA	K	PFAM Helix-turn-helix type 3
MAG.T21.45_01696	700598.Niako_0976	1.4e-38	165.6	Sphingobacteriia			4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016				Bacteria	1IT05@117747,4NRT5@976,COG0720@1,COG0720@2	NA|NA|NA	H	COG0720 6-pyruvoyl-tetrahydropterin synthase
MAG.T21.45_01697	1122176.KB903574_gene4816	9e-63	248.4	Sphingobacteriia	comEA			ko:K02237		M00429			ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2			Bacteria	1INMF@117747,4NE88@976,COG1555@1,COG1555@2	NA|NA|NA	L	Psort location OuterMembrane, score
MAG.T21.45_01698	1122176.KB903568_gene3470	3.7e-96	359.0	Sphingobacteriia													Bacteria	1IQVW@117747,4NEGK@976,COG0535@1,COG0535@2	NA|NA|NA	S	radical SAM domain protein
MAG.T21.45_01699	1122176.KB903568_gene3471	8.5e-38	162.9	Bacteroidetes	glnB			ko:K04751,ko:K04752	ko02020,map02020				ko00000,ko00001				Bacteria	4NQG9@976,COG0347@1,COG0347@2	NA|NA|NA	K	Belongs to the P(II) protein family
MAG.T21.45_01700	1122176.KB903568_gene3472	3.6e-166	591.3	Sphingobacteriia	amtB			ko:K03320					ko00000,ko02000	1.A.11		iJN678.amt2	Bacteria	1IR56@117747,4NDV2@976,COG0004@1,COG0004@2	NA|NA|NA	P	Ammonium Transporter Family
MAG.T21.45_01701	760192.Halhy_4850	1.7e-93	349.7	Sphingobacteriia													Bacteria	1IRCZ@117747,28IEX@1,2Z8GX@2,4NGBY@976	NA|NA|NA	S	Putative beta-barrel porin-2, OmpL-like. bbp2
MAG.T21.45_01702	471854.Dfer_0448	2.1e-169	601.7	Cytophagia	glnII		6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727		R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147				Bacteria	47JHR@768503,4NGG2@976,COG0174@1,COG0174@2	NA|NA|NA	E	PFAM glutamine synthetase catalytic region
MAG.T21.45_01703	929562.Emtol_0670	1.2e-148	533.1	Cytophagia	pepT	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.4	ko:K01258					ko00000,ko01000,ko01002				Bacteria	47K1G@768503,4NE7N@976,COG2195@1,COG2195@2	NA|NA|NA	E	Cleaves the N-terminal amino acid of tripeptides
MAG.T21.45_01704	760192.Halhy_4645	4.3e-92	345.1	Sphingobacteriia													Bacteria	1ITRX@117747,4NF0N@976,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.45_01705	760192.Halhy_4644	1.8e-87	329.3	Sphingobacteriia													Bacteria	1ISIV@117747,4NGVF@976,COG2227@1,COG2227@2	NA|NA|NA	H	PFAM Methyltransferase type 12
MAG.T21.45_01706	760192.Halhy_4643	4.2e-52	211.8	Bacteria				ko:K02660	ko02020,ko02025,map02020,map02025				ko00000,ko00001,ko02035,ko02044				Bacteria	COG1858@1,COG1858@2	NA|NA|NA	C	electron transfer activity
MAG.T21.45_01707	1122621.ATZA01000074_gene1835	1.1e-139	503.4	Sphingobacteriia	pepQ	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271					ko00000,ko01000,ko01002				Bacteria	1IPQC@117747,4NG40@976,COG0006@1,COG0006@2	NA|NA|NA	E	Peptidase M24B, X-Pro dipeptidase aminopeptidase
MAG.T21.45_01708	1219065.VPR01S_26_00270	9.5e-24	115.9	Vibrionales													Bacteria	1N0TK@1224,1S8V9@1236,1XXSA@135623,COG4327@1,COG4327@2	NA|NA|NA	S	membrane
MAG.T21.45_01709	1453500.AT05_10045	5.8e-268	929.9	Flavobacteriia	actP			ko:K14393					ko00000,ko02000	2.A.21.7			Bacteria	1HXQN@117743,4NHPT@976,COG4147@1,COG4147@2	NA|NA|NA	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MAG.T21.45_01710	760192.Halhy_6506	4.3e-58	231.5	Sphingobacteriia			5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29	ko:K06177,ko:K06179,ko:K06180					ko00000,ko01000,ko03009,ko03016				Bacteria	1IQTT@117747,4NHKH@976,COG0564@1,COG0564@2	NA|NA|NA	J	Pseudouridine synthase
MAG.T21.45_01711	760192.Halhy_6505	5.7e-206	724.2	Sphingobacteriia	ribF		2.7.1.26,2.7.7.2	ko:K07011,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1IP9Q@117747,4NFP0@976,COG0196@1,COG0196@2,COG1216@1,COG1216@2	NA|NA|NA	H	glycosyl transferase family 2
MAG.T21.45_01712	984262.SGRA_0352	3e-113	415.2	Sphingobacteriia	mrp			ko:K03593					ko00000,ko03029,ko03036				Bacteria	1IQKF@117747,4NF5I@976,COG0489@1,COG0489@2	NA|NA|NA	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MAG.T21.45_01713	1122176.KB903598_gene4667	1.7e-22	111.7	Sphingobacteriia	nifU												Bacteria	1IU7U@117747,4NSHJ@976,COG0694@1,COG0694@2	NA|NA|NA	O	NifU-like domain
MAG.T21.45_01714	153721.MYP_268	1.7e-92	345.9	Cytophagia	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.10,4.1.1.23	ko:K01591,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS17585	Bacteria	47JHC@768503,4NE12@976,COG0284@1,COG0284@2	NA|NA|NA	F	Orotidine 5''-phosphate decarboxylase
MAG.T21.45_01715	760192.Halhy_6118	2.3e-129	469.2	Sphingobacteriia	cho	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342,ko:K03703,ko:K03763,ko:K05984	ko00230,ko00240,ko01100,ko03030,ko03420,ko03430,ko03440,map00230,map00240,map01100,map03030,map03420,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1IQ4K@117747,4NEQX@976,COG0322@1,COG0322@2,COG0847@1,COG0847@2	NA|NA|NA	L	DNA polymerase III, epsilon subunit
MAG.T21.45_01716	1122176.KB903531_gene3045	1e-130	473.4	Sphingobacteriia													Bacteria	1IV2A@117747,4NEXD@976,COG3876@1,COG3876@2	NA|NA|NA	S	Protein of unknown function (DUF1343)
MAG.T21.45_01717	760192.Halhy_6306	3.1e-152	545.0	Sphingobacteriia	cefD												Bacteria	1IR6S@117747,4NF4G@976,COG0520@1,COG0520@2	NA|NA|NA	E	Aminotransferase class-V
MAG.T21.45_01718	760192.Halhy_6023	2e-45	188.3	Sphingobacteriia	nfuA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010467,GO:0015976,GO:0016043,GO:0016226,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564		ko:K07400,ko:K13628,ko:K15724					ko00000,ko03016				Bacteria	1ISU6@117747,4NS6K@976,COG0316@1,COG0316@2	NA|NA|NA	S	Belongs to the HesB IscA family
MAG.T21.45_01719	760192.Halhy_6124	4.1e-131	475.7	Bacteria			3.4.17.22	ko:K07752					ko00000,ko01000,ko01002				Bacteria	COG4412@1,COG4412@2	NA|NA|NA	S	peptidase activity, acting on L-amino acid peptides
MAG.T21.45_01720	760192.Halhy_6126	9.6e-207	726.1	Sphingobacteriia	icd	GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000			e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144	Bacteria	1IPFB@117747,4PKW6@976,COG0538@1,COG0538@2	NA|NA|NA	C	Isocitrate dehydrogenase
MAG.T21.45_01721	760192.Halhy_6127	3.6e-140	504.6	Sphingobacteriia	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1IR3Y@117747,4NEB9@976,COG2255@1,COG2255@2	NA|NA|NA	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MAG.T21.45_01722	760192.Halhy_0001	2.4e-190	671.8	Sphingobacteriia	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837		ko:K02313	ko02020,ko04112,map02020,map04112				ko00000,ko00001,ko03032,ko03036				Bacteria	1INXF@117747,4NE6Q@976,COG0593@1,COG0593@2	NA|NA|NA	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MAG.T21.45_01725	485918.Cpin_1909	2.2e-43	183.0	Sphingobacteriia													Bacteria	1IP54@117747,2CA60@1,2Z88P@2,4NJRW@976	NA|NA|NA		
MAG.T21.45_01726	1123037.AUDE01000014_gene409	2.9e-93	348.6	Flavobacteriia	hbdA		1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120		R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000				Bacteria	1HWQX@117743,4NGU8@976,COG1250@1,COG1250@2	NA|NA|NA	I	Dehydrogenase
MAG.T21.45_01727	485918.Cpin_6906	2.2e-75	289.3	Sphingobacteriia	rlmL	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.173,2.1.1.191,2.1.1.264,2.1.1.72	ko:K00571,ko:K06969,ko:K12297			R07234	RC00003	ko00000,ko01000,ko02048,ko03009				Bacteria	1IVC8@117747,4P1C0@976,COG1092@1,COG1092@2	NA|NA|NA	J	S-adenosylmethionine-dependent methyltransferase
MAG.T21.45_01728	760192.Halhy_5712	6.1e-189	667.5	Sphingobacteriia	dnaG	GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576		ko:K02316	ko03030,map03030				ko00000,ko00001,ko01000,ko03032				Bacteria	1IR9Y@117747,4NENT@976,COG0358@1,COG0358@2	NA|NA|NA	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MAG.T21.45_01729	760192.Halhy_5881	2.5e-160	571.6	Sphingobacteriia	fbaA	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPX5@117747,4NF5C@976,COG0191@1,COG0191@2	NA|NA|NA	G	Fructose-bisphosphate aldolase
MAG.T21.45_01730	760192.Halhy_5882	1.4e-133	482.6	Sphingobacteriia	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418		R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110			iNJ661.Rv3913	Bacteria	1IQ1P@117747,4NEVX@976,COG0492@1,COG0492@2	NA|NA|NA	C	Thioredoxin reductase
MAG.T21.45_01731	760192.Halhy_6426	5.3e-209	733.8	Sphingobacteriia													Bacteria	1IQE5@117747,4NF48@976,COG2939@1,COG2939@2	NA|NA|NA	E	PFAM peptidase S10 serine carboxypeptidase
MAG.T21.45_01732	760192.Halhy_5883	7.6e-86	324.7	Bacteroidetes			3.4.21.62,3.4.21.66	ko:K01342,ko:K08651,ko:K14645	ko02024,map02024				ko00000,ko00001,ko01000,ko01002,ko03110				Bacteria	4NSXZ@976,COG1404@1,COG1404@2	NA|NA|NA	O	Subtilase family
MAG.T21.45_01733	760192.Halhy_6048	2.6e-186	658.3	Sphingobacteriia	ffh	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9			Bacteria	1INMC@117747,4NDZ2@976,COG0541@1,COG0541@2	NA|NA|NA	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MAG.T21.45_01734	760192.Halhy_6156	3e-183	648.7	Sphingobacteriia	yidC	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150		ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9			Bacteria	1IQAZ@117747,4NESJ@976,COG0706@1,COG0706@2	NA|NA|NA	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
MAG.T21.45_01735	1122176.KB903609_gene5226	1.9e-38	165.6	Sphingobacteriia	pyrR	GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100		R00966	RC00063	ko00000,ko00001,ko01000,ko03000				Bacteria	1ISDB@117747,4NNRI@976,COG2065@1,COG2065@2	NA|NA|NA	F	Pyrimidine operon attenuation protein uracil phosphoribosyltransferase
MAG.T21.45_01736	760192.Halhy_5426	7.9e-156	557.0	Sphingobacteriia													Bacteria	1IQ7C@117747,4NF3K@976,COG1150@1,COG1150@2	NA|NA|NA	C	Fe-S oxidoreductase
MAG.T21.45_01737	760192.Halhy_5427	1.7e-105	389.0	Sphingobacteriia													Bacteria	1IP0Z@117747,4NDZS@976,COG0247@1,COG0247@2	NA|NA|NA	C	Fe-S oxidoreductase
MAG.T21.45_01738	485918.Cpin_5890	3.9e-23	114.8	Sphingobacteriia													Bacteria	1ITP3@117747,28NRS@1,2ZBQZ@2,4NMM5@976	NA|NA|NA		
MAG.T21.45_01739	760192.Halhy_0345	5.3e-30	137.5	Bacteroidetes													Bacteria	294GD@1,2ZRW7@2,4P6UK@976	NA|NA|NA	S	SpoOM protein
MAG.T21.45_01741	760192.Halhy_0344	3.6e-148	531.6	Sphingobacteriia	phr		4.1.99.3	ko:K01669					ko00000,ko01000,ko03400				Bacteria	1IQZJ@117747,4NEDW@976,COG0415@1,COG0415@2	NA|NA|NA	L	DNA photolyase
MAG.T21.45_01742	1538644.KO02_14555	3.4e-48	198.4	Sphingobacteriia	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24,2.7.7.87	ko:K00859,ko:K07566	ko00770,ko01100,map00770,map01100	M00120	R00130,R10463	RC00002,RC00078,RC00745	ko00000,ko00001,ko00002,ko01000,ko03009,ko03016				Bacteria	1IS97@117747,4NQKS@976,COG0237@1,COG0237@2	NA|NA|NA	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MAG.T21.45_01743	760192.Halhy_0071	1.8e-78	299.7	Sphingobacteriia	ribD	GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_1624,iLJ478.TM1828	Bacteria	1IP03@117747,4NFJE@976,COG0117@1,COG0117@2,COG1985@1,COG1985@2	NA|NA|NA	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MAG.T21.45_01744	760192.Halhy_0070	8.7e-51	206.8	Bacteroidetes													Bacteria	2EN6Q@1,33FUJ@2,4P4IW@976	NA|NA|NA	S	HNH endonuclease
MAG.T21.45_01745	985255.APHJ01000035_gene7	7.5e-49	200.7	Gillisia	mnmC		2.1.1.61,2.4.2.29,4.2.1.151	ko:K00773,ko:K11782,ko:K15461	ko00130,ko01110,map00130,map01110		R00601,R03789,R08702,R10209,R10666	RC00003,RC00053,RC00060,RC00063,RC01483,RC03232	ko00000,ko00001,ko01000,ko03016				Bacteria	1HZG3@117743,2P6HK@244698,4NE5S@976,COG4121@1,COG4121@2	NA|NA|NA	S	S-adenosyl-L-methionine-dependent methyltransferase
MAG.T21.45_01746	1122176.KB903609_gene5268	1e-163	582.8	Sphingobacteriia	pdhB		1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_2753	Bacteria	1IPGW@117747,4NE4N@976,COG0022@1,COG0022@2	NA|NA|NA	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MAG.T21.45_01747	1122179.KB890419_gene24	1.7e-310	1072.0	Bacteroidetes													Bacteria	4NI14@976,COG4447@1,COG4447@2	NA|NA|NA	S	cellulose binding
MAG.T21.45_01748	1296416.JACB01000040_gene1918	3.3e-39	170.6	Aquimarina													Bacteria	1HXNK@117743,2YKDW@290174,4NHCZ@976,COG0457@1,COG0457@2,COG4995@1,COG4995@2	NA|NA|NA	S	CHAT domain
MAG.T21.45_01749	760192.Halhy_5013	1.4e-35	156.4	Bacteria				ko:K03088,ko:K03091					ko00000,ko03021				Bacteria	COG1595@1,COG1595@2	NA|NA|NA	K	DNA-templated transcription, initiation
MAG.T21.45_01753	760192.Halhy_5741	1.8e-106	393.3	Sphingobacteriia													Bacteria	1IWTU@117747,4NS9R@976,COG4870@1,COG4870@2	NA|NA|NA	O	PFAM Papain family cysteine protease
MAG.T21.45_01754	760192.Halhy_5740	6.3e-100	372.5	Bacteria				ko:K07126					ko00000				Bacteria	COG4249@1,COG4249@2	NA|NA|NA	S	B-1 B cell differentiation
MAG.T21.45_01755	1008457.BAEX01000017_gene1667	2.4e-25	120.9	Myroides	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131				Bacteria	1I1AD@117743,47I5H@76831,4NM5B@976,COG0105@1,COG0105@2	NA|NA|NA	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MAG.T21.45_01756	760192.Halhy_0351	5.1e-254	884.0	Sphingobacteriia	mutS2			ko:K07456	ko03430,map03430				ko00000,ko00001,ko03400				Bacteria	1IP8R@117747,4NFE6@976,COG1193@1,COG1193@2	NA|NA|NA	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MAG.T21.45_01757	760192.Halhy_5525	2.2e-143	515.4	Sphingobacteriia	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000			iIT341.HP0663,iJN678.aroC	Bacteria	1IQ18@117747,4NDXJ@976,COG0082@1,COG0082@2	NA|NA|NA	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MAG.T21.45_01758	435591.BDI_2190	7.7e-48	196.8	Porphyromonadaceae				ko:K07095					ko00000				Bacteria	22XUV@171551,2FSMW@200643,4NM4G@976,COG0622@1,COG0622@2	NA|NA|NA	S	Phosphoesterase
MAG.T21.45_01759	760192.Halhy_6393	3.2e-47	195.7	Bacteroidetes													Bacteria	4NU9X@976,COG3595@1,COG3595@2	NA|NA|NA		
MAG.T21.45_01761	760192.Halhy_6395	1.6e-51	209.1	Sphingobacteriia				ko:K03088					ko00000,ko03021				Bacteria	1ISH7@117747,4NQCH@976,COG1595@1,COG1595@2	NA|NA|NA	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MAG.T21.45_01762	1121904.ARBP01000002_gene6734	2.2e-23	115.9	Cytophagia													Bacteria	47QZZ@768503,4PJMQ@976,COG3637@1,COG3637@2	NA|NA|NA	M	Outer membrane protein beta-barrel domain
MAG.T21.45_01763	760192.Halhy_6086	3.6e-63	248.1	Sphingobacteriia	engB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363		ko:K03978					ko00000,ko03036				Bacteria	1ISQ4@117747,4NEA9@976,COG0218@1,COG0218@2	NA|NA|NA	D	Necessary for normal cell division and for the maintenance of normal septation
MAG.T21.45_01764	760192.Halhy_6085	2.7e-193	681.8	Bacteroidetes	plsB		2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	4NK5H@976,COG2937@1,COG2937@2	NA|NA|NA	I	Belongs to the GPAT DAPAT family
MAG.T21.45_01765	760192.Halhy_6084	1.8e-53	215.7	Bacteria	exoN1												Bacteria	COG5018@1,COG5018@2	NA|NA|NA	L	Exonuclease
MAG.T21.45_01766	1122179.KB890423_gene2318	1.1e-228	799.3	Sphingobacteriia	pccB		2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQ23@117747,4NEMJ@976,COG4799@1,COG4799@2	NA|NA|NA	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MAG.T21.45_01767	760192.Halhy_0199	1e-149	536.6	Sphingobacteriia	aspB	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297	2.6.1.1,2.6.1.14	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230		R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052	RC00006,RC00025	ko00000,ko00001,ko01000,ko01007			iHN637.CLJU_RS06550	Bacteria	1INY0@117747,4NENS@976,COG0436@1,COG0436@2	NA|NA|NA	E	PFAM Aminotransferase class I and II
MAG.T21.45_01768	760192.Halhy_5400	7.1e-228	797.0	Sphingobacteriia	ptrB	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143				ko00000,ko00001,ko01000,ko01002				Bacteria	1IQQY@117747,4NEQS@976,COG1770@1,COG1770@2	NA|NA|NA	E	Peptidase S9, prolyl oligopeptidase, catalytic domain
MAG.T21.45_01769	1122176.KB903609_gene5145	2e-83	315.5	Sphingobacteriia	nth		4.2.99.18	ko:K10773	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1IPXY@117747,4NFF3@976,COG0177@1,COG0177@2	NA|NA|NA	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MAG.T21.45_01770	760192.Halhy_1083	9e-138	496.9	Sphingobacteriia	purM		6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQ5E@117747,4NE4E@976,COG0150@1,COG0150@2	NA|NA|NA	F	Phosphoribosylformylglycinamidine cyclo-ligase
MAG.T21.45_01771	760192.Halhy_1084	7.3e-111	407.5	Sphingobacteriia	yebA												Bacteria	1IRH5@117747,4NECF@976,COG0739@1,COG0739@2	NA|NA|NA	M	Peptidase family M23
MAG.T21.45_01772	760192.Halhy_1085	2e-52	212.2	Sphingobacteriia	yqgE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464		ko:K07735					ko00000,ko03000				Bacteria	1ISYC@117747,4NFQA@976,COG1678@1,COG1678@2	NA|NA|NA	K	acr, cog1678
MAG.T21.45_01773	760192.Halhy_1086	3.3e-105	388.3	Sphingobacteriia	fabD		2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1IQ02@117747,4NE1D@976,COG0331@1,COG0331@2	NA|NA|NA	I	malonyl CoA-acyl carrier protein transacylase
MAG.T21.45_01774	760192.Halhy_1087	8e-87	327.4	Sphingobacteriia													Bacteria	1ISFF@117747,4NH1Q@976,COG2972@1,COG2972@2	NA|NA|NA	T	Histidine kinase
MAG.T21.45_01775	760192.Halhy_1088	4.8e-94	350.9	Sphingobacteriia													Bacteria	1J04J@117747,4NNIK@976,COG3279@1,COG3279@2	NA|NA|NA	T	LytTr DNA-binding domain
MAG.T21.45_01776	760192.Halhy_1089	1.2e-96	361.3	Bacteria				ko:K21449					ko00000,ko02000	1.B.40.2			Bacteria	COG0384@1,COG0384@2,COG5295@1,COG5295@2	NA|NA|NA	S	isomerase activity
MAG.T21.45_01778	1123248.KB893337_gene2343	3.5e-65	255.0	Sphingobacteriia	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000			iLJ478.TM1520	Bacteria	1IP8Q@117747,4NDX2@976,COG0289@1,COG0289@2	NA|NA|NA	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MAG.T21.45_01779	760192.Halhy_1093	0.0	1190.3	Sphingobacteriia	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391		ko:K03555	ko03430,map03430				ko00000,ko00001,ko03400				Bacteria	1IR7Y@117747,4NEGB@976,COG0249@1,COG0249@2	NA|NA|NA	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MAG.T21.45_01780	760192.Halhy_1094	2.9e-49	201.1	Sphingobacteriia	fdx1			ko:K03522,ko:K05337					ko00000,ko04147				Bacteria	1ISEN@117747,4NNF9@976,COG1145@1,COG1145@2	NA|NA|NA	C	4Fe-4S binding domain
MAG.T21.45_01781	1305737.JAFX01000001_gene863	1.1e-77	296.6	Cytophagia													Bacteria	47MT3@768503,4NEUB@976,COG1028@1,COG1028@2	NA|NA|NA	IQ	KR domain
MAG.T21.45_01782	1250006.JHZZ01000001_gene1869	9.9e-76	290.4	Polaribacter			3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000				Bacteria	1IJQW@117743,3VVN2@52959,4PMBK@976,COG0596@1,COG0596@2	NA|NA|NA	S	Ndr family
MAG.T21.45_01783	700598.Niako_4356	4.3e-134	485.0	Sphingobacteriia													Bacteria	1IQ2M@117747,4NFDJ@976,COG2234@1,COG2234@2	NA|NA|NA	S	peptidase
MAG.T21.45_01784	391596.PBAL39_08584	3.3e-154	551.6	Sphingobacteriia	malT			ko:K16211					ko00000,ko02000	2.A.2.6			Bacteria	1IPIA@117747,4NE3F@976,COG2211@1,COG2211@2	NA|NA|NA	G	Major Facilitator
MAG.T21.45_01785	1121904.ARBP01000008_gene3340	3.3e-63	248.8	Cytophagia	yjiA	GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0033554,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716											Bacteria	47PR1@768503,4NENH@976,COG0523@1,COG0523@2	NA|NA|NA	S	Cobalamin synthesis protein cobW C-terminal domain
MAG.T21.45_01786	760192.Halhy_3452	9.6e-158	563.9	Bacteria													Bacteria	COG1195@1,COG1195@2	NA|NA|NA	L	single-stranded DNA binding
MAG.T21.45_01788	641143.HMPREF9331_01858	4.6e-194	684.9	Capnocytophaga				ko:K16089					ko00000,ko02000	1.B.14.1,1.B.14.10			Bacteria	1EQC5@1016,1HX6P@117743,4NF05@976,COG1629@1,COG4771@2	NA|NA|NA	M	TonB-dependent receptor
MAG.T21.45_01789	1434325.AZQN01000008_gene2864	1.2e-26	126.3	Cytophagia				ko:K09950					ko00000				Bacteria	47P8H@768503,4NMZ8@976,COG3495@1,COG3495@2	NA|NA|NA	S	Protein conserved in bacteria
MAG.T21.45_01790	1121904.ARBP01000002_gene6764	6.8e-222	776.9	Cytophagia			3.2.1.1,3.2.1.135	ko:K01176,ko:K21575	ko00500,ko01100,ko04973,map00500,map01100,map04973		R02108,R02112,R11262		ko00000,ko00001,ko01000		GH13		Bacteria	47MXA@768503,4NEXF@976,COG0366@1,COG0366@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 13 family
MAG.T21.45_01791	1122176.KB903531_gene2974	8.5e-81	307.4	Bacteroidetes			3.2.1.1,3.4.21.96	ko:K01176,ko:K01361,ko:K07004,ko:K21571	ko00500,ko01100,ko04973,map00500,map01100,map04973		R02108,R02112,R11262		ko00000,ko00001,ko01000,ko01002,ko03110		GH13		Bacteria	4PKH4@976,COG0366@1,COG0366@2	NA|NA|NA	G	SusE outer membrane protein
MAG.T21.45_01792	1122176.KB903531_gene2973	1.7e-251	875.5	Sphingobacteriia				ko:K21572					ko00000,ko02000	8.A.46.1,8.A.46.3			Bacteria	1IREB@117747,4NEA6@976,COG3637@1,COG3637@2	NA|NA|NA	M	RagB SusD domain protein
MAG.T21.45_01793	1122176.KB903531_gene2972	0.0	1088.6	Sphingobacteriia				ko:K21573					ko00000,ko02000	1.B.14.6.1			Bacteria	1INQB@117747,4P1Z5@976,COG1629@1,COG4771@2	NA|NA|NA	P	TonB dependent receptor
MAG.T21.45_01794	880073.Calab_1596	9.2e-53	215.7	unclassified Bacteria			2.7.13.3	ko:K07647,ko:K11527,ko:K20974	ko02020,ko02025,map02020,map02025	M00455,M00820			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	2NP58@2323,COG0642@1,COG0642@2	NA|NA|NA	T	His Kinase A (phosphoacceptor) domain
MAG.T21.45_01795	1122176.KB903554_gene3953	4.1e-73	281.6	Sphingobacteriia	ytnP												Bacteria	1INUA@117747,4NE98@976,COG0491@1,COG0491@2	NA|NA|NA	S	beta-lactamase
MAG.T21.45_01796	760192.Halhy_5566	1e-47	196.4	Sphingobacteriia	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000			iLJ478.TM1825,iSB619.SA_RS08940,iSFV_1184.SFV_0380	Bacteria	1ISBW@117747,4NNUC@976,COG0054@1,COG0054@2	NA|NA|NA	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MAG.T21.45_01797	760192.Halhy_5565	3.6e-51	208.4	Sphingobacteriia	cpoB		3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036				Bacteria	1IQ2D@117747,4NEM2@976,COG1729@1,COG1729@2	NA|NA|NA	S	Tetratricopeptide
MAG.T21.45_01798	760192.Halhy_5564	8.2e-151	540.0	Sphingobacteriia	pdhA		1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1IPU9@117747,4NF2J@976,COG1071@1,COG1071@2	NA|NA|NA	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MAG.T21.45_01799	760192.Halhy_5563	5.5e-94	351.3	Sphingobacteriia	recF	GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576		ko:K03629,ko:K07459	ko03440,map03440				ko00000,ko00001,ko03400				Bacteria	1IP1J@117747,4NFHN@976,COG1195@1,COG1195@2	NA|NA|NA	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MAG.T21.45_01800	1047013.AQSP01000106_gene1768	2.8e-72	279.6	unclassified Bacteria			2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100		R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002				Bacteria	2NP8H@2323,COG0405@1,COG0405@2	NA|NA|NA	E	Gamma-glutamyltranspeptidase
MAG.T21.45_01801	493475.GARC_4526	7.5e-50	204.1	Alteromonadaceae				ko:K07090					ko00000				Bacteria	1MVY3@1224,1S21M@1236,467A8@72275,COG0730@1,COG0730@2	NA|NA|NA	S	Sulfite exporter TauE/SafE
MAG.T21.45_01802	984262.SGRA_1428	3.4e-40	172.6	Bacteroidetes	bioF2	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	4NI7H@976,COG3146@1,COG3146@2	NA|NA|NA	S	Protein conserved in bacteria
MAG.T21.45_01803	1237149.C900_03399	1.3e-13	83.2	Bacteroidetes													Bacteria	28WK7@1,2ZIK7@2,4P8ND@976	NA|NA|NA		
MAG.T21.45_01804	1396418.BATQ01000048_gene6227	1.1e-08	68.2	Verrucomicrobiae													Bacteria	29WV6@1,2IVQM@203494,30IGP@2,46XF1@74201	NA|NA|NA		
MAG.T21.45_01805	929703.KE386491_gene2094	1.8e-68	265.8	Cytophagia	eda		4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000				Bacteria	47PM4@768503,4NEFY@976,COG0800@1,COG0800@2	NA|NA|NA	G	PFAM KDPG and KHG aldolase
MAG.T21.45_01806	760192.Halhy_0039	2.7e-120	438.3	Bacteroidetes	tesB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575		ko:K10805	ko01040,map01040				ko00000,ko00001,ko01000,ko01004			iAF1260.b0452,iB21_1397.B21_00408,iBWG_1329.BWG_0334,iEC55989_1330.EC55989_0466,iECBD_1354.ECBD_3203,iECB_1328.ECB_00404,iECDH10B_1368.ECDH10B_0408,iECDH1ME8569_1439.ECDH1ME8569_0437,iECD_1391.ECD_00404,iECH74115_1262.ECH74115_0541,iECIAI1_1343.ECIAI1_0456,iECIAI39_1322.ECIAI39_0221,iECO103_1326.ECO103_0429,iECO111_1330.ECO111_0485,iECO26_1355.ECO26_0487,iECSE_1348.ECSE_0478,iECSP_1301.ECSP_0520,iECUMN_1333.ECUMN_0492,iECW_1372.ECW_m0524,iECs_1301.ECs0506,iEKO11_1354.EKO11_3394,iETEC_1333.ETEC_0505,iEcDH1_1363.EcDH1_3157,iEcE24377_1341.EcE24377A_0488,iEcHS_1320.EcHS_A0529,iEcSMS35_1347.EcSMS35_0496,iEcolC_1368.EcolC_3163,iG2583_1286.G2583_0564,iJO1366.b0452,iSSON_1240.SSON_0440,iUMNK88_1353.UMNK88_505,iWFL_1372.ECW_m0524,iY75_1357.Y75_RS02335,iZ_1308.Z0564,ic_1306.c0571	Bacteria	4NEY8@976,COG1946@1,COG1946@2	NA|NA|NA	I	PFAM Acyl-CoA thioesterase
MAG.T21.45_01807	66692.ABC1225	1.2e-26	126.3	Bacillus	ybaK			ko:K03976					ko00000,ko01000,ko03016				Bacteria	1V6JF@1239,1ZGGN@1386,4HHFK@91061,COG2606@1,COG2606@2	NA|NA|NA	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MAG.T21.45_01808	760192.Halhy_0034	1.5e-21	109.0	Sphingobacteriia	ytxJ												Bacteria	1ITHB@117747,4NSE6@976,COG3118@1,COG3118@2	NA|NA|NA	O	Protein of unknown function (DUF2847)
MAG.T21.45_01809	760192.Halhy_4963	1.1e-82	314.3	Sphingobacteriia	aarF												Bacteria	1IRIK@117747,4NDUP@976,COG0661@1,COG0661@2	NA|NA|NA	S	ABC1 family
MAG.T21.45_01810	760192.Halhy_5053	7.1e-81	307.4	Bacteroidetes													Bacteria	4NFX6@976,COG0668@1,COG0668@2	NA|NA|NA	M	mechanosensitive ion channel
MAG.T21.45_01811	760192.Halhy_5052	1e-97	363.2	Sphingobacteriia	zupT			ko:K07238					ko00000,ko02000	2.A.5.5			Bacteria	1INMZ@117747,4NGQ8@976,COG0428@1,COG0428@2	NA|NA|NA	P	ZIP Zinc transporter
MAG.T21.45_01812	760192.Halhy_5051	6.6e-116	424.1	Sphingobacteriia													Bacteria	1IRNF@117747,4NH1Q@976,COG2972@1,COG2972@2	NA|NA|NA	T	PFAM histidine kinase
MAG.T21.45_01813	760192.Halhy_1105	5.7e-84	317.4	Sphingobacteriia													Bacteria	1IS4B@117747,4NI3K@976,COG3279@1,COG3279@2	NA|NA|NA	K	COG3279 Response regulator of the LytR AlgR family
MAG.T21.45_01814	468059.AUHA01000002_gene1369	3.8e-153	548.5	Sphingobacteriia	deaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.6.4.13	ko:K05592	ko03018,map03018				ko00000,ko00001,ko01000,ko03009,ko03019				Bacteria	1IQEP@117747,4NEJV@976,COG0513@1,COG0513@2	NA|NA|NA	L	Belongs to the DEAD box helicase family
MAG.T21.45_01815	880070.Cycma_1813	2.7e-49	201.8	Cytophagia	msrB		1.8.4.11,1.8.4.12	ko:K07305,ko:K12267					ko00000,ko01000				Bacteria	47PZ4@768503,4NQEY@976,COG0229@1,COG0229@2	NA|NA|NA	O	peptide methionine sulfoxide reductase
MAG.T21.45_01816	313603.FB2170_11651	0.0	1294.3	Maribacter													Bacteria	1HWS9@117743,2PI8X@252356,4NEZQ@976,COG4447@1,COG4447@2	NA|NA|NA	S	cellulose binding
MAG.T21.45_01819	468059.AUHA01000002_gene715	9.7e-43	180.6	Sphingobacteriia													Bacteria	1IRTS@117747,4NQZB@976,COG4632@1,COG4632@2	NA|NA|NA	G	Phosphodiester glycosidase
MAG.T21.45_01820	760192.Halhy_5122	1e-80	307.4	Sphingobacteriia	xseA		3.1.11.6	ko:K03601	ko03430,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	1IRPR@117747,4NE64@976,COG1570@1,COG1570@2	NA|NA|NA	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MAG.T21.45_01821	755732.Fluta_1522	4e-08	63.5	Flavobacteriia	xseB		3.1.11.6	ko:K03602	ko03430,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	1I6NE@117743,4PA4N@976,COG1722@1,COG1722@2	NA|NA|NA	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MAG.T21.45_01822	929562.Emtol_2021	8.8e-36	156.8	Cytophagia	folK		2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000			iLJ478.TM0041	Bacteria	47QG8@768503,4NGE8@976,COG0801@1,COG0801@2	NA|NA|NA	H	TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MAG.T21.45_01823	760192.Halhy_5126	1.2e-67	263.1	Sphingobacteriia	dgk		2.7.1.113	ko:K15518	ko00230,map00230		R01967	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	1IXF2@117747,4PM5R@976,COG1428@1,COG1428@2	NA|NA|NA	F	Thymidylate kinase
MAG.T21.45_01824	925409.KI911562_gene716	3e-29	134.4	Sphingobacteriia	rhaM		5.1.3.32	ko:K03534			R10819	RC00563	ko00000,ko01000				Bacteria	1ISVY@117747,4NSEM@976,COG3254@1,COG3254@2	NA|NA|NA	G	Involved in the anomeric conversion of L-rhamnose
MAG.T21.45_01825	1122176.KB903576_gene4934	4.4e-59	235.3	Sphingobacteriia			3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQD9@117747,4NE5W@976,COG0010@1,COG0010@2	NA|NA|NA	E	Belongs to the arginase family
MAG.T21.45_01826	760192.Halhy_4800	3.8e-134	485.0	Sphingobacteriia	murF		6.3.2.10,6.3.2.13	ko:K01928,ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502		R02788,R04573,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	1IQA5@117747,4NDWD@976,COG0770@1,COG0770@2	NA|NA|NA	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MAG.T21.45_01827	760192.Halhy_4799	2.3e-202	711.8	Sphingobacteriia	pkn1												Bacteria	1IQK8@117747,4NE51@976,COG1262@1,COG1262@2	NA|NA|NA	S	gliding motility-associated lipoprotein GldJ
MAG.T21.45_01828	760192.Halhy_4798	2.7e-58	232.6	Sphingobacteriia													Bacteria	1INP3@117747,4NG13@976,COG4772@1,COG4772@2	NA|NA|NA	P	Type IX secretion system membrane protein PorP/SprF
MAG.T21.45_01829	760192.Halhy_4797	0.0	1100.1	Sphingobacteriia	porU												Bacteria	1IW9T@117747,4NDY7@976,COG1572@1,COG1572@2	NA|NA|NA	S	Peptidase family C25
MAG.T21.45_01830	760192.Halhy_4796	4e-170	604.4	Sphingobacteriia	porV												Bacteria	1IPX7@117747,4NDZW@976,COG2067@1,COG2067@2	NA|NA|NA	I	long-chain fatty acid transport protein
MAG.T21.45_01831	616991.JPOO01000001_gene2879	8.8e-48	197.2	Arenibacter													Bacteria	1HZ05@117743,23GCP@178469,28HQQ@1,2Z7YB@2,4NJCY@976	NA|NA|NA		
MAG.T21.45_01832	929562.Emtol_3117	2e-98	365.9	Cytophagia	yhhX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	1.1.1.371	ko:K16044	ko00562,ko01120,map00562,map01120		R09954	RC00182	ko00000,ko00001,ko01000				Bacteria	47KWZ@768503,4NEQB@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_01833	143224.JQMD01000002_gene1380	5e-54	217.6	Flavobacteriia	maa		2.3.1.79	ko:K00661					ko00000,ko01000				Bacteria	1IIUF@117743,4NH27@976,COG0110@1,COG0110@2	NA|NA|NA	S	Hexapeptide repeat of succinyl-transferase
MAG.T21.45_01834	929562.Emtol_1373	4.8e-96	357.8	Cytophagia													Bacteria	47K27@768503,4NFMU@976,COG3828@1,COG3828@2	NA|NA|NA	S	Trehalose utilisation
MAG.T21.45_01835	761193.Runsl_3649	2.4e-169	602.4	Cytophagia			3.1.1.53	ko:K05970					ko00000,ko01000				Bacteria	47JV2@768503,4NEDP@976,COG3250@1,COG3250@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 2 family
MAG.T21.45_01836	545695.TREAZ_2513	2.3e-103	383.3	Spirochaetes			3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100		R06200,R11307,R11308		ko00000,ko00001,ko01000		GH5,GH9		Bacteria	2J89M@203691,COG2730@1,COG2730@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MAG.T21.45_01837	362418.IW19_21710	4.4e-88	331.6	Flavobacterium	yjjN	GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019520,GO:0019583,GO:0019584,GO:0019752,GO:0032787,GO:0034193,GO:0034195,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575										iSSON_1240.SSON_4504	Bacteria	1IIK7@117743,2NUME@237,4NHCK@976,COG1063@1,COG1063@2	NA|NA|NA	E	Alcohol dehydrogenase
MAG.T21.45_01838	1121897.AUGO01000001_gene1156	1.2e-48	199.5	Flavobacterium	yqgC			ko:K09793					ko00000				Bacteria	1IMGE@117743,2NVFI@237,4NP3I@976,COG2839@1,COG2839@2	NA|NA|NA	S	Protein of unknown function (DUF456)
MAG.T21.45_01840	700598.Niako_4822	4.9e-115	422.2	Bacteroidetes													Bacteria	4PMM6@976,COG0210@1,COG0210@2	NA|NA|NA	L	COGs COG0210 Superfamily I DNA and RNA helicase
MAG.T21.45_01841	760192.Halhy_0308	3.8e-269	934.5	Sphingobacteriia													Bacteria	1IQE0@117747,4NFWD@976,COG1452@1,COG1452@2	NA|NA|NA	M	Organic solvent tolerance protein OstA
MAG.T21.45_01842	760192.Halhy_0307	1.2e-91	343.6	Sphingobacteriia	amiA		3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036				Bacteria	1ISH9@117747,4NGKC@976,COG0860@1,COG0860@2	NA|NA|NA	M	Cell wall hydrolase autolysin
MAG.T21.45_01843	760192.Halhy_0306	1.5e-40	173.7	Sphingobacteriia	ttg2C			ko:K02067	ko02010,map02010	M00210,M00669,M00670			ko00000,ko00001,ko00002,ko02000	3.A.1.27			Bacteria	1IQZY@117747,4NHT9@976,COG1463@1,COG1463@2	NA|NA|NA	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component
MAG.T21.45_01844	760192.Halhy_5045	1.1e-200	706.4	Sphingobacteriia	msbA2			ko:K06147,ko:K11085	ko02010,map02010				ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	1IQ3V@117747,4PKCT@976,COG1132@1,COG1132@2	NA|NA|NA	V	ABC transporter
MAG.T21.45_01845	760192.Halhy_5044	9.3e-49	200.7	Bacteria				ko:K12976					ko00000,ko01000,ko01005				Bacteria	COG3637@1,COG3637@2	NA|NA|NA	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MAG.T21.45_01846	760192.Halhy_5960	4.2e-168	597.4	Sphingobacteriia	ilvC	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000			iEC042_1314.EC042_4152,iECABU_c1320.ECABU_c42560,iECED1_1282.ECED1_4460,iECO103_1326.ECO103_4390,iECO111_1330.ECO111_4600,iECO26_1355.ECO26_4812,iECP_1309.ECP_3967,iECSE_1348.ECSE_4057,iECUMN_1333.ECUMN_4300,iEcE24377_1341.EcE24377A_4285,iEcSMS35_1347.EcSMS35_4140,iIT341.HP0330,iLF82_1304.LF82_1103	Bacteria	1IQ69@117747,4NFYV@976,COG0059@1,COG0059@2	NA|NA|NA	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MAG.T21.45_01847	1122176.KB903547_gene1107	1.5e-151	542.7	Sphingobacteriia	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000				Bacteria	1INNU@117747,4NEY2@976,COG1171@1,COG1171@2	NA|NA|NA	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MAG.T21.45_01848	760192.Halhy_5054	3.8e-40	171.0	Sphingobacteriia	MA20_25125												Bacteria	1ISGG@117747,4NNQG@976,COG2947@1,COG2947@2	NA|NA|NA	S	EVE domain
MAG.T21.45_01849	929562.Emtol_4269	1.2e-114	419.9	Cytophagia													Bacteria	47NP1@768503,4NGXN@976,COG3367@1,COG3367@2	NA|NA|NA	S	Domain of unknown function (DUF1611_N) Rossmann-like domain
MAG.T21.45_01850	1189612.A33Q_2080	0.0	1632.8	Cytophagia				ko:K09992					ko00000				Bacteria	47MAT@768503,4NDVK@976,COG2133@1,COG2133@2,COG3291@1,COG3291@2,COG3828@1,COG3828@2,COG4654@1,COG4654@2	NA|NA|NA	CG	Cytochrome c, class I
MAG.T21.45_01851	1123278.KB893390_gene831	1.1e-171	609.8	Cytophagia													Bacteria	47MYW@768503,4NEPB@976,COG3119@1,COG3119@2	NA|NA|NA	P	Sulfatase
MAG.T21.45_01852	509635.N824_13805	2.1e-154	552.4	Sphingobacteriia				ko:K06921					ko00000				Bacteria	1IR0Q@117747,4NGWE@976,COG1672@1,COG1672@2	NA|NA|NA	S	PFAM Archaeal ATPase
MAG.T21.45_01854	700598.Niako_3636	1.6e-217	762.3	Sphingobacteriia	araB		2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100		R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000				Bacteria	1IQ36@117747,4NEFQ@976,COG1069@1,COG1069@2	NA|NA|NA	G	Belongs to the ribulokinase family
MAG.T21.45_01855	700598.Niako_3637	2e-97	362.1	Sphingobacteriia	araD		4.1.2.17,5.1.3.4	ko:K01628,ko:K03077	ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120	M00550	R02262,R05850	RC00603,RC00604,RC01479	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPP5@117747,4NGMP@976,COG0235@1,COG0235@2	NA|NA|NA	G	PFAM Class II aldolase adducin
MAG.T21.45_01856	714943.Mucpa_4125	9.7e-203	713.0	Sphingobacteriia	araA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100		R01761	RC00516	ko00000,ko00001,ko01000			iAPECO1_1312.APECO1_1922,iB21_1397.B21_00063,iBWG_1329.BWG_0058,iE2348C_1286.E2348C_0063,iECBD_1354.ECBD_3555,iECD_1391.ECD_00064,iECED1_1282.ECED1_0061,iECIAI1_1343.ECIAI1_0062,iECNA114_1301.ECNA114_0050,iECO103_1326.ECO103_0063,iECO26_1355.ECO26_0064,iECOK1_1307.ECOK1_0061,iECP_1309.ECP_0063,iECS88_1305.ECS88_0065,iECSE_1348.ECSE_0062,iECW_1372.ECW_m0060,iEKO11_1354.EKO11_3852,iEcE24377_1341.EcE24377A_0064,iEcHS_1320.EcHS_A0066,iEcSMS35_1347.EcSMS35_0064,iEcolC_1368.EcolC_3595,iLF82_1304.LF82_0105,iLJ478.TM0276,iNRG857_1313.NRG857_00320,iSBO_1134.SBO_0049,iSSON_1240.SSON_0068,iUMN146_1321.UM146_23095,iUTI89_1310.UTI89_C0067,iWFL_1372.ECW_m0060	Bacteria	1IPX0@117747,4NHGG@976,COG2160@1,COG2160@2	NA|NA|NA	G	Catalyzes the conversion of L-arabinose to L-ribulose
MAG.T21.45_01858	1123057.P872_01255	8.3e-141	507.3	Cytophagia													Bacteria	47KU0@768503,4NF48@976,COG2939@1,COG2939@2	NA|NA|NA	E	Serine carboxypeptidase
MAG.T21.45_01859	760192.Halhy_0223	0.0	1141.3	Bacteria													Bacteria	COG4447@1,COG4447@2	NA|NA|NA	S	cellulose binding
MAG.T21.45_01861	1279009.ADICEAN_02200	8.6e-12	76.6	Bacteria													Bacteria	COG3748@1,COG3748@2	NA|NA|NA	S	Urate oxidase N-terminal
MAG.T21.45_01862	616991.JPOO01000001_gene4514	1.5e-158	566.2	Arenibacter			3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600		R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000				Bacteria	1HZWB@117743,23G8D@178469,4NEM3@976,COG3119@1,COG3119@2	NA|NA|NA	P	Type I phosphodiesterase / nucleotide pyrophosphatase
MAG.T21.45_01863	760192.Halhy_0782	3.2e-100	372.1	Sphingobacteriia													Bacteria	1IPME@117747,4NFR2@976,COG1262@1,COG1262@2	NA|NA|NA	S	PFAM Formylglycine-generating sulfatase enzyme
MAG.T21.45_01864	1121904.ARBP01000004_gene790	1.3e-278	965.3	Cytophagia	MA20_01050		1.97.1.9	ko:K12527	ko00450,map00450		R07229	RC02420	ko00000,ko00001,ko01000				Bacteria	47KDW@768503,4NG9R@976,COG0493@1,COG0493@2,COG1143@1,COG1143@2	NA|NA|NA	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MAG.T21.45_01865	1288963.ADIS_2622	6.1e-247	860.1	Cytophagia	korA		1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	47KM5@768503,4NEP3@976,COG0674@1,COG0674@2,COG1014@1,COG1014@2	NA|NA|NA	C	Pyruvate ferredoxin/flavodoxin oxidoreductase
MAG.T21.45_01866	1239962.C943_04413	7e-155	553.5	Cytophagia	MA20_01040		1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	47KXJ@768503,4NIE0@976,COG1013@1,COG1013@2	NA|NA|NA	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
MAG.T21.45_01867	983544.Lacal_2708	3.8e-132	478.0	Flavobacteriia	sdr2		1.4.3.10,1.4.3.4	ko:K00274,ko:K03343	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R01151,R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000				Bacteria	1I09T@117743,4NGST@976,COG1231@1,COG1231@2	NA|NA|NA	E	Flavin containing amine oxidoreductase
MAG.T21.45_01868	760192.Halhy_5546	7.1e-279	966.5	Sphingobacteriia	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019				Bacteria	1INMK@117747,4NE4Q@976,COG1185@1,COG1185@2	NA|NA|NA	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MAG.T21.45_01870	760192.Halhy_5547	2.4e-30	137.9	Sphingobacteriia	rpsO	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02956	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1ITE1@117747,4NS7U@976,COG0184@1,COG0184@2	NA|NA|NA	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MAG.T21.45_01871	760192.Halhy_0359	8.7e-104	383.6	Sphingobacteriia	etfA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575		ko:K03522					ko00000,ko04147				Bacteria	1IPHN@117747,4NFSE@976,COG2025@1,COG2025@2	NA|NA|NA	C	Electron transfer flavoprotein
MAG.T21.45_01872	760192.Halhy_0360	5.8e-79	300.8	Sphingobacteriia	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114		ko:K03521					ko00000				Bacteria	1IQTX@117747,4NFWB@976,COG2086@1,COG2086@2	NA|NA|NA	C	Electron transfer flavoprotein
MAG.T21.45_01873	1122176.KB903562_gene3444	5.2e-16	90.5	Sphingobacteriia	hemY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02498					ko00000				Bacteria	1ITXW@117747,4NUU1@976,COG3071@1,COG3071@2	NA|NA|NA	H	Tetratricopeptide repeat
MAG.T21.45_01874	760192.Halhy_0364	1.5e-61	243.4	Sphingobacteriia	mutS2			ko:K07456	ko03430,map03430				ko00000,ko00001,ko03400				Bacteria	1IP9N@117747,4NNNV@976,COG1193@1,COG1193@2	NA|NA|NA	L	Smr domain
MAG.T21.45_01875	1408813.AYMG01000010_gene449	8.7e-115	420.2	Sphingobacteriia	arnC		2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100		R01009	RC00005	ko00000,ko00001,ko01000,ko01003		GT2		Bacteria	1IPAW@117747,4NEVT@976,COG0463@1,COG0463@2	NA|NA|NA	M	glycosyl transferase family 2
MAG.T21.45_01877	1434325.AZQN01000008_gene3018	1.8e-08	66.2	Cytophagia													Bacteria	2DM6B@1,31WK9@2,47QS1@768503,4NQK1@976	NA|NA|NA	S	Protein of unknown function (DUF4199)
MAG.T21.45_01878	760192.Halhy_0936	5.6e-98	364.8	Sphingobacteriia	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000				Bacteria	1IRB4@117747,4NDUZ@976,COG0044@1,COG0044@2	NA|NA|NA	F	Dihydroorotase, multifunctional complex type
MAG.T21.45_01879	1122176.KB903532_gene2607	3.3e-96	359.8	Bacteroidetes													Bacteria	4NUWQ@976,COG1287@1,COG1287@2	NA|NA|NA	S	oligosaccharyl transferase activity
MAG.T21.45_01880	760192.Halhy_0935	4.9e-165	588.2	Sphingobacteriia													Bacteria	1IQP4@117747,4NFQQ@976,COG2304@1,COG2304@2	NA|NA|NA	S	TIGRFAM N-terminal double-transmembrane domain
MAG.T21.45_01881	1122176.KB903532_gene2610	1.2e-77	296.2	Sphingobacteriia	queE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047	1.97.1.4,4.3.99.3	ko:K04068,ko:K10026	ko00790,ko01100,map00790,map01100		R04710,R10002	RC02989	ko00000,ko00001,ko01000,ko03016				Bacteria	1IQ8P@117747,4NESC@976,COG0602@1,COG0602@2	NA|NA|NA	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MAG.T21.45_01882	760192.Halhy_4557	0.0	1288.1	Sphingobacteriia													Bacteria	1J0XK@117747,4PKAS@976,COG1629@1,COG1629@2	NA|NA|NA	P	TonB-dependent Receptor Plug Domain
MAG.T21.45_01883	929703.KE386491_gene200	2.3e-132	479.2	Cytophagia													Bacteria	47MZ4@768503,4NFUK@976,COG4198@1,COG4198@2	NA|NA|NA	S	Starch-binding associating with outer membrane
MAG.T21.45_01884	760192.Halhy_1256	6.4e-210	738.0	Sphingobacteriia	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89,3.6.4.12	ko:K00982,ko:K10742	ko03030,map03030				ko00000,ko00001,ko01000,ko03032				Bacteria	1IWRJ@117747,4NGDS@976,COG0210@1,COG0210@2,COG1112@1,COG1112@2,COG1391@1,COG1391@2	NA|NA|NA	L	Superfamily I DNA and RNA
MAG.T21.45_01885	1122176.KB903587_gene4385	1.2e-84	319.7	Sphingobacteriia	ppm1		2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100		R01009	RC00005	ko00000,ko00001,ko01000,ko01003		GT2		Bacteria	1IRP1@117747,4NEHI@976,COG1216@1,COG1216@2	NA|NA|NA	S	PFAM Glycosyl transferase family 2
MAG.T21.45_01887	1123278.KB893400_gene4134	4.2e-143	514.6	Cytophagia	tetA			ko:K08151,ko:K08153		M00668,M00717			ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75,2.A.1.2.8			Bacteria	47N08@768503,4NFM7@976,COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
MAG.T21.45_01888	153721.MYP_211	2.1e-128	466.1	Cytophagia			3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728			ko00000,ko00001,ko00002,ko01000,ko01002,ko03110				Bacteria	47KF5@768503,4NFCS@976,COG0265@1,COG0265@2	NA|NA|NA	O	PDZ domain (Also known as DHR or GLGF)
MAG.T21.45_01889	760192.Halhy_4264	1.4e-146	526.2	Sphingobacteriia	pdhC		1.2.4.1,2.3.1.12	ko:K00162,ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R02569,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02857,RC02882	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1IPXC@117747,4NFB9@976,COG0508@1,COG0508@2	NA|NA|NA	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MAG.T21.45_01890	760192.Halhy_4263	2.4e-30	138.3	Sphingobacteriia				ko:K06929					ko00000				Bacteria	1ITJY@117747,4NSE8@976,COG1832@1,COG1832@2	NA|NA|NA	S	CoA binding domain
MAG.T21.45_01891	760192.Halhy_4261	5.6e-93	347.4	Sphingobacteriia	mazG	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66,3.6.1.9	ko:K02428,ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100		R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323	RC00002	ko00000,ko00001,ko01000,ko03036			iJN678.sll1005	Bacteria	1IR2F@117747,4NEA3@976,COG1694@1,COG3956@2	NA|NA|NA	S	PFAM MazG nucleotide pyrophosphohydrolase
MAG.T21.45_01892	760192.Halhy_4440	2.5e-64	251.9	Sphingobacteriia	yqdE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944		ko:K03617,ko:K08999					ko00000				Bacteria	1IRH8@117747,4NGSW@976,COG1259@1,COG1259@2	NA|NA|NA	S	PFAM Uncharacterised ACR, COG1259
MAG.T21.45_01893	760192.Halhy_1375	2.2e-129	468.8	Sphingobacteriia	ltaA		4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230		R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000				Bacteria	1IQZT@117747,4NEIH@976,COG2008@1,COG2008@2	NA|NA|NA	E	Threonine aldolase
MAG.T21.45_01896	755732.Fluta_2872	1.5e-63	249.6	Flavobacteriia	budA	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0047605	4.1.1.5	ko:K01575	ko00650,ko00660,map00650,map00660		R02948	RC00812	ko00000,ko00001,ko01000				Bacteria	1HX22@117743,4NKWJ@976,COG3527@1,COG3527@2	NA|NA|NA	Q	Alpha-acetolactate decarboxylase
MAG.T21.45_01897	760192.Halhy_1367	3.2e-70	271.9	Sphingobacteriia	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000			iIT341.HP0566,iLJ478.TM1522	Bacteria	1IP6C@117747,4NF26@976,COG0253@1,COG0253@2	NA|NA|NA	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MAG.T21.45_01899	1123248.KB893325_gene1177	1.3e-24	119.8	Sphingobacteriia													Bacteria	1ITBC@117747,4NQSN@976,COG0454@1,COG0456@2	NA|NA|NA	K	Acetyltransferase (GNAT) domain
MAG.T21.45_01900	1185876.BN8_06470	4e-229	801.2	Cytophagia			3.5.1.97	ko:K07116					ko00000,ko01000				Bacteria	47JE7@768503,4NGXQ@976,COG2366@1,COG2366@2	NA|NA|NA	S	Penicillin amidase
MAG.T21.45_01901	929562.Emtol_2583	1.7e-150	539.3	Cytophagia													Bacteria	47M48@768503,4NF4G@976,COG0520@1,COG0520@2	NA|NA|NA	E	Aminotransferase class-V
MAG.T21.45_01902	760192.Halhy_4149	1.4e-71	276.9	Sphingobacteriia													Bacteria	1IQP5@117747,4NETA@976,COG0438@1,COG0438@2	NA|NA|NA	M	PFAM Glycosyl transferase, group 1
MAG.T21.45_01903	760192.Halhy_1341	3.1e-45	187.6	Sphingobacteriia	iscA			ko:K13628					ko00000,ko03016				Bacteria	1IT1Q@117747,4NQC8@976,COG0316@1,COG0316@2	NA|NA|NA	S	Belongs to the HesB IscA family
MAG.T21.45_01904	760192.Halhy_1342	3.9e-61	240.7	Sphingobacteriia	iscU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0036455,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564		ko:K04488					ko00000			iAPECO1_1312.APECO1_3996,iB21_1397.B21_02385,iBWG_1329.BWG_2293,iE2348C_1286.E2348C_2812,iEC042_1314.EC042_2733,iEC55989_1330.EC55989_2814,iECABU_c1320.ECABU_c28350,iECBD_1354.ECBD_1155,iECB_1328.ECB_02421,iECDH10B_1368.ECDH10B_2696,iECDH1ME8569_1439.ECDH1ME8569_2456,iECD_1391.ECD_02421,iECED1_1282.ECED1_2960,iECH74115_1262.ECH74115_3761,iECIAI1_1343.ECIAI1_2581,iECIAI39_1322.ECIAI39_2730,iECNA114_1301.ECNA114_2608,iECO103_1326.ECO103_3046,iECO111_1330.ECO111_3253,iECO26_1355.ECO26_3576,iECOK1_1307.ECOK1_2878,iECP_1309.ECP_2534,iECS88_1305.ECS88_2705,iECSE_1348.ECSE_2815,iECSF_1327.ECSF_2373,iECSP_1301.ECSP_3473,iECUMN_1333.ECUMN_2849,iECW_1372.ECW_m2755,iECs_1301.ECs3395,iEKO11_1354.EKO11_1204,iETEC_1333.ETEC_2686,iEcDH1_1363.EcDH1_1139,iEcE24377_1341.EcE24377A_2814,iEcHS_1320.EcHS_A2680,iEcSMS35_1347.EcSMS35_2682,iEcolC_1368.EcolC_1148,iG2583_1286.G2583_3059,iJO1366.b2529,iSDY_1059.SDY_2725,iSFV_1184.SFV_2577,iSF_1195.SF2576,iSFxv_1172.SFxv_2832,iSSON_1240.SSON_2611,iS_1188.S2748,iUMN146_1321.UM146_04055,iUMNK88_1353.UMNK88_3182,iUTI89_1310.UTI89_C2851,iWFL_1372.ECW_m2755,iY75_1357.Y75_RS13200,iZ_1308.Z3796,ic_1306.c3055	Bacteria	1IS99@117747,4NM9Z@976,COG0822@1,COG0822@2	NA|NA|NA	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters
MAG.T21.45_01905	760192.Halhy_1343	6.5e-197	693.3	Sphingobacteriia	iscS	GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122		R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029			iPC815.YPO2896,iYL1228.KPN_02862	Bacteria	1IQ14@117747,4NG58@976,COG1104@1,COG1104@2	NA|NA|NA	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins
MAG.T21.45_01906	1122179.KB890423_gene2322	1.9e-15	90.1	Bacteroidetes	mutA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016999,GO:0017144,GO:0019541,GO:0019678,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046459,GO:0071704,GO:0071944	2.7.7.7,5.4.99.2,5.4.99.63	ko:K01847,ko:K03763,ko:K14447	ko00230,ko00240,ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,ko03030,ko03430,ko03440,map00230,map00240,map00280,map00630,map00640,map00720,map01100,map01120,map01200,map03030,map03430,map03440	M00260,M00373,M00376,M00741	R00375,R00376,R00377,R00378,R00833,R09292	RC00395,RC02795,RC02835	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	4NDVE@976,COG1884@1,COG1884@2	NA|NA|NA	I	Methylmalonyl-CoA mutase
MAG.T21.45_01907	760192.Halhy_1407	7.5e-91	340.9	Sphingobacteriia		GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944											Bacteria	1IZ4M@117747,4NFHZ@976,COG0628@1,COG0628@2	NA|NA|NA	S	AI-2E family transporter
MAG.T21.45_01908	760192.Halhy_4134	1.4e-109	402.9	Sphingobacteriia	queG	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979					ko00000,ko01000,ko03016				Bacteria	1IP9F@117747,4NFCJ@976,COG1600@1,COG1600@2	NA|NA|NA	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MAG.T21.45_01909	760192.Halhy_0841	8.4e-10	69.7	Sphingobacteriia													Bacteria	1IUES@117747,4P9X5@976,COG5512@1,COG5512@2	NA|NA|NA	S	Protein of unknown function (DUF721)
MAG.T21.45_01910	929703.KE386491_gene2742	9.2e-93	347.1	Cytophagia	aspG		3.4.19.5,3.5.1.1,3.5.1.26	ko:K01424,ko:K01444,ko:K13051	ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142		R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002				Bacteria	47JDT@768503,4NE3D@976,COG1446@1,COG1446@2	NA|NA|NA	E	PFAM peptidase T2 asparaginase 2
MAG.T21.45_01911	760192.Halhy_4715	4.8e-229	801.2	Bacteria			3.2.1.4,5.2.1.8	ko:K01179,ko:K03768,ko:K08738	ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko03110	3.D.4.6	GH5,GH9		Bacteria	COG3291@1,COG3291@2	NA|NA|NA	S	metallopeptidase activity
MAG.T21.45_01912	760192.Halhy_4716	5.3e-273	948.3	Bacteroidetes													Bacteria	28H9B@1,2Z7M3@2,4NGVQ@976	NA|NA|NA		
MAG.T21.45_01913	929703.KE386491_gene672	1.1e-54	219.9	Cytophagia	ccmA		3.6.3.41	ko:K01990,ko:K02193	ko02010,map02010	M00254,M00259			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.107			Bacteria	47PDC@768503,4NN9G@976,COG1131@1,COG1131@2	NA|NA|NA	V	PFAM ABC transporter
MAG.T21.45_01914	487796.Flav2ADRAFT_0355	2.2e-39	169.5	Flavobacteriia	lpxA		2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1HWK9@117743,4NEBA@976,COG1043@1,COG1043@2	NA|NA|NA	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MAG.T21.45_01915	760192.Halhy_4709	2.4e-150	538.9	Sphingobacteriia	fabZ	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171	3.5.1.108,4.2.1.59	ko:K02372,ko:K02535,ko:K13599,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020	M00060,M00083,M00498,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022				Bacteria	1IQB1@117747,4NEJ3@976,COG0764@1,COG0764@2,COG0774@1,COG0774@2	NA|NA|NA	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
MAG.T21.45_01916	743722.Sph21_1540	7e-59	234.6	Sphingobacteriia	lpxD		2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1IP38@117747,4NE5G@976,COG1044@1,COG1044@2	NA|NA|NA	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MAG.T21.45_01917	760192.Halhy_4711	1.5e-102	379.4	Sphingobacteriia	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.107,2.5.1.61,4.2.1.75	ko:K01749,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084,R03165,R03194	RC00003,RC00871,RC01861,RC02317	ko00000,ko00001,ko00002,ko01000			iEC55989_1330.EC55989_4275,iECH74115_1262.ECH74115_5243,iECIAI1_1343.ECIAI1_3991,iECO103_1326.ECO103_4362,iECO111_1330.ECO111_4628,iECO26_1355.ECO26_4784,iECSE_1348.ECSE_4086,iEKO11_1354.EKO11_4554,iHN637.CLJU_RS15760,iPC815.YPO3849	Bacteria	1IQUA@117747,4NHH4@976,COG0181@1,COG0181@2	NA|NA|NA	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MAG.T21.45_01918	760192.Halhy_4712	2.8e-35	155.6	Bacteria	hemD		2.1.1.107,4.2.1.75	ko:K01719,ko:K13542,ko:K13543	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000				Bacteria	COG1587@1,COG1587@2	NA|NA|NA	H	uroporphyrinogen-III synthase activity
MAG.T21.45_01920	997884.HMPREF1068_01121	1.8e-64	253.8	Bacteroidaceae				ko:K21571					ko00000				Bacteria	2FPTN@200643,4AW2R@815,4NGY2@976,COG1262@1,COG1262@2,COG3656@1,COG3656@2	NA|NA|NA	KLT	Sulfatase-modifying factor enzyme 1
MAG.T21.45_01921	760192.Halhy_0240	1.6e-254	885.9	Sphingobacteriia													Bacteria	1IQ6P@117747,4NHA4@976,COG1523@1,COG1523@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 13 family
MAG.T21.45_01922	760192.Halhy_0107	1.3e-120	439.9	Sphingobacteriia	rlmI	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.191	ko:K06969					ko00000,ko01000,ko03009				Bacteria	1INTU@117747,4NG9S@976,COG1092@1,COG1092@2	NA|NA|NA	J	PUA domain containing protein
MAG.T21.45_01923	1122176.KB903609_gene5259	1.8e-44	186.8	Bacteroidetes													Bacteria	4NPE1@976,COG5505@1,COG5505@2	NA|NA|NA	S	Protein of unknown function (DUF819)
MAG.T21.45_01924	1122176.KB903531_gene3134	1.2e-202	712.6	Sphingobacteriia	dapE		3.5.1.16,3.5.1.18	ko:K01436,ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	1IQ95@117747,4NFGE@976,COG0624@1,COG0624@2	NA|NA|NA	E	Peptidase, family M20 M25 M40
MAG.T21.45_01925	760192.Halhy_5703	5.2e-59	234.6	Sphingobacteriia	dacA	GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849	2.7.7.85	ko:K18672					ko00000,ko01000				Bacteria	1IQKY@117747,4NG3Z@976,COG1624@1,COG1624@2	NA|NA|NA	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MAG.T21.45_01927	760192.Halhy_0836	1.5e-75	289.3	Sphingobacteriia	miaE			ko:K06169					ko00000,ko01000,ko03016				Bacteria	1ISGF@117747,4NFY4@976,COG4445@1,COG4445@2	NA|NA|NA	FJ	COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA
MAG.T21.45_01928	1121890.AUDO01000010_gene273	2e-43	182.2	Flavobacterium	msrB		1.8.4.12	ko:K07305					ko00000,ko01000				Bacteria	1IG0P@117743,2NVKN@237,4NQEY@976,COG0229@1,COG0229@2	NA|NA|NA	O	SelR domain
MAG.T21.45_01930	760192.Halhy_0120	1.5e-183	649.0	Sphingobacteriia	rimO	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564	2.8.4.4	ko:K14441			R10652	RC00003,RC03217	ko00000,ko01000,ko03009				Bacteria	1IP0Q@117747,4NEJK@976,COG0621@1,COG0621@2	NA|NA|NA	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
MAG.T21.45_01932	1122176.KB903547_gene1118	4.3e-231	807.4	Sphingobacteriia	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPT9@117747,4NFHP@976,COG0129@1,COG0129@2	NA|NA|NA	EG	Belongs to the IlvD Edd family
MAG.T21.45_01933	1122176.KB903547_gene1117	1.1e-253	882.5	Sphingobacteriia	ilvB		2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPTP@117747,4NENG@976,COG0028@1,COG0028@2	NA|NA|NA	EH	Acetolactate synthase, large subunit
MAG.T21.45_01934	760192.Halhy_6524	2.1e-59	235.3	Sphingobacteriia	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000			iAF1260.b3670,iAPECO1_1312.APECO1_2782,iB21_1397.B21_03496,iBWG_1329.BWG_3361,iE2348C_1286.E2348C_3985,iEC042_1314.EC042_4025,iECABU_c1320.ECABU_c41570,iECBD_1354.ECBD_0033,iECB_1328.ECB_03554,iECDH10B_1368.ECDH10B_3853,iECDH1ME8569_1439.ECDH1ME8569_3555,iECD_1391.ECD_03554,iECED1_1282.ECED1_4366,iECH74115_1262.ECH74115_5103,iECIAI1_1343.ECIAI1_3846,iECIAI39_1322.ECIAI39_4272,iECNA114_1301.ECNA114_3825,iECO111_1330.ECO111_4494,iECO26_1355.ECO26_4913,iECOK1_1307.ECOK1_4123,iECP_1309.ECP_3877,iECS88_1305.ECS88_4095,iECSE_1348.ECSE_3954,iECSF_1327.ECSF_3518,iECSP_1301.ECSP_4721,iECUMN_1333.ECUMN_4201,iECW_1372.ECW_m3968,iECs_1301.ECs4611,iEKO11_1354.EKO11_0033,iETEC_1333.ETEC_3964,iEcDH1_1363.EcDH1_0033,iEcE24377_1341.EcE24377A_4179,iEcHS_1320.EcHS_A3883,iEcSMS35_1347.EcSMS35_4037,iEcolC_1368.EcolC_0029,iG2583_1286.G2583_4464,iJO1366.b3670,iJR904.b3670,iLF82_1304.LF82_1110,iNRG857_1313.NRG857_18305,iPC815.YPO2294,iSFV_1184.SFV_3839,iSF_1195.SF3791,iSFxv_1172.SFxv_4123,iSSON_1240.SSON_3624,iS_1188.S3977,iUMN146_1321.UM146_18560,iUMNK88_1353.UMNK88_4479,iUTI89_1310.UTI89_C4226,iWFL_1372.ECW_m3968,iY75_1357.Y75_RS18770,iYL1228.KPN_04073,iZ_1308.Z5164,ic_1306.c4595	Bacteria	1IP7C@117747,4NIDK@976,COG0440@1,COG0440@2	NA|NA|NA	E	synthase small subunit
MAG.T21.45_01935	1123277.KB893217_gene4436	0.0	1194.1	Cytophagia													Bacteria	47K6G@768503,4NDU8@976,COG1629@1,COG4771@2	NA|NA|NA	P	PFAM TonB-dependent Receptor Plug
MAG.T21.45_01936	760192.Halhy_5728	7.5e-171	607.1	Sphingobacteriia													Bacteria	1IP72@117747,4NHNF@976,COG0521@1,COG0521@2	NA|NA|NA	H	Starch-binding associating with outer membrane
MAG.T21.45_01937	1123278.KB893455_gene782	1.1e-24	120.6	Cytophagia													Bacteria	2A2ZH@1,30RE0@2,47Q4Z@768503,4NP88@976	NA|NA|NA	S	Domain of unknown function (DUF4397)
MAG.T21.45_01938	1121904.ARBP01000010_gene2359	6.2e-79	302.8	Cytophagia													Bacteria	47P6C@768503,4NK2V@976,COG4733@1,COG4733@2,COG4935@1,COG4935@2	NA|NA|NA	G	PFAM Fibronectin type III domain
MAG.T21.45_01939	760192.Halhy_5496	5.5e-276	956.8	Sphingobacteriia	yhgF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896		ko:K06959					ko00000				Bacteria	1IPB3@117747,4NETD@976,COG2183@1,COG2183@2	NA|NA|NA	K	Tex-like protein N-terminal domain
MAG.T21.45_01940	313606.M23134_03189	6.4e-35	154.1	Cytophagia	ksgA1												Bacteria	47RVM@768503,4NPMV@976,COG3963@1,COG3963@2	NA|NA|NA	I	Ribosomal RNA adenine dimethylase
MAG.T21.45_01941	760192.Halhy_3706	0.0	1134.8	Sphingobacteriia				ko:K03296					ko00000	2.A.6.2			Bacteria	1IPZZ@117747,4NDZG@976,COG0841@1,COG0841@2	NA|NA|NA	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MAG.T21.45_01942	760192.Halhy_3707	9.1e-78	297.4	Sphingobacteriia													Bacteria	1IQVF@117747,4NF23@976,COG0845@1,COG0845@2	NA|NA|NA	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAG.T21.45_01943	760192.Halhy_3708	7.1e-75	288.1	Sphingobacteriia													Bacteria	1INS3@117747,4NF4X@976,COG1538@1,COG1538@2	NA|NA|NA	MU	PFAM Outer membrane efflux protein
MAG.T21.45_01944	391598.FBBAL38_06345	1.6e-26	126.3	Flavobacteriia				ko:K09017					ko00000,ko03000				Bacteria	1I3T6@117743,4NQ99@976,COG1309@1,COG1309@2	NA|NA|NA	K	tetR family
MAG.T21.45_01946	760192.Halhy_4502	3.4e-103	381.3	Sphingobacteriia													Bacteria	1IPN9@117747,4NEAI@976,COG1028@1,COG1028@2	NA|NA|NA	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)
MAG.T21.45_01947	1120965.AUBV01000001_gene3537	3.3e-139	501.9	Cytophagia	rutC		4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130		R06602	RC01549,RC02148	ko00000,ko00001,ko01000				Bacteria	47XV2@768503,4P1NX@976,COG0251@1,COG0251@2,COG0667@1,COG0667@2	NA|NA|NA	CJ	Endoribonuclease L-PSP
MAG.T21.45_01948	1120965.AUBV01000001_gene3536	4.7e-141	508.1	Bacteria	steT			ko:K03294					ko00000	2.A.3.2			Bacteria	COG0531@1,COG0531@2	NA|NA|NA	E	amino acid
MAG.T21.45_01949	290512.Paes_1157	1.8e-27	129.4	Chlorobi													Bacteria	1FF7S@1090,COG4704@1,COG4704@2	NA|NA|NA	S	Fibrobacter succinogenes major domain (Fib_succ_major)
MAG.T21.45_01950	755732.Fluta_2560	0.0	1172.9	Flavobacteriia													Bacteria	1HX2H@117743,4NDZG@976,COG0841@1,COG0841@2	NA|NA|NA	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MAG.T21.45_01951	525373.HMPREF0766_13077	4.1e-70	271.9	Sphingobacteriia				ko:K18302		M00642			ko00000,ko00002,ko01504,ko02000	2.A.6.2,8.A.1			Bacteria	1IS62@117747,4NF23@976,COG0845@1,COG0845@2	NA|NA|NA	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAG.T21.45_01952	1239962.C943_01926	1.8e-78	300.1	Cytophagia													Bacteria	47KIE@768503,4NE4S@976,COG1538@1,COG1538@2	NA|NA|NA	MU	PFAM Outer membrane efflux protein
MAG.T21.45_01953	1123277.KB893243_gene227	2.2e-47	195.7	Cytophagia	ttgR												Bacteria	47MM9@768503,4NKU9@976,COG1309@1,COG1309@2	NA|NA|NA	K	WHG domain
MAG.T21.45_01954	760192.Halhy_3536	1.3e-38	166.4	Sphingobacteriia				ko:K03088					ko00000,ko03021				Bacteria	1ISGD@117747,4NMAK@976,COG1595@1,COG1595@2	NA|NA|NA	K	PFAM RNA polymerase sigma factor 70, region 4 type 2
MAG.T21.45_01955	1122176.KB903549_gene1228	8e-14	84.0	Sphingobacteriia													Bacteria	1ITH5@117747,2A95J@1,30YA2@2,4NP9E@976	NA|NA|NA		
MAG.T21.45_01956	1121898.Q766_06220	1.1e-17	97.8	Flavobacterium													Bacteria	1HYD6@117743,2NV26@237,4NEUW@976,COG3595@1,COG3595@2	NA|NA|NA		
MAG.T21.45_01957	1122176.KB903609_gene5254	8.8e-24	116.7	Bacteria													Bacteria	2EAE0@1,334HK@2	NA|NA|NA		
MAG.T21.45_01958	1313421.JHBV01000014_gene3962	8.5e-44	183.3	Sphingobacteriia	rlmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.177	ko:K00783					ko00000,ko01000,ko03009				Bacteria	1ISE3@117747,4NMFP@976,COG1576@1,COG1576@2	NA|NA|NA	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MAG.T21.45_01959	1122176.KB903531_gene2949	9.6e-54	216.9	Sphingobacteriia													Bacteria	1IS27@117747,4NECA@976,COG0705@1,COG0705@2	NA|NA|NA	S	Rhomboid family
MAG.T21.45_01960	760192.Halhy_0646	1e-38	167.2	Sphingobacteriia													Bacteria	1ITFE@117747,4NNYV@976,COG1434@1,COG1434@2	NA|NA|NA	S	DUF218 domain
MAG.T21.45_01961	1122223.KB890696_gene92	5.7e-52	210.7	Deinococcus-Thermus	nudF		3.6.1.13	ko:K01515	ko00230,map00230		R01054	RC00002	ko00000,ko00001,ko01000				Bacteria	1WIME@1297,COG0494@1,COG0494@2	NA|NA|NA	L	PFAM NUDIX hydrolase
MAG.T21.45_01962	760192.Halhy_0133	2.2e-85	322.0	Sphingobacteriia	ftsE	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363		ko:K09812	ko02010,map02010	M00256			ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140			Bacteria	1IQ4U@117747,4NEP2@976,COG2884@1,COG2884@2	NA|NA|NA	D	ABC transporter
MAG.T21.45_01963	1123277.KB893239_gene1118	1.3e-90	340.5	Cytophagia	add		3.5.4.2,3.5.4.4	ko:K01488,ko:K19572,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340		R01244,R01560,R02556	RC00477	ko00000,ko00001,ko01000				Bacteria	47TPF@768503,4NG5W@976,COG1816@1,COG1816@2	NA|NA|NA	F	Adenosine/AMP deaminase
MAG.T21.45_01964	1054213.HMPREF9946_03165	1.5e-30	139.4	Proteobacteria			3.1.31.1	ko:K01174					ko00000,ko01000				Bacteria	1N145@1224,COG1525@1,COG1525@2	NA|NA|NA	L	nuclease
MAG.T21.45_01965	1122176.KB903550_gene4290	6.8e-26	125.2	Bacteria	hom		1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS06610	Bacteria	COG0460@1,COG0460@2	NA|NA|NA	E	homoserine dehydrogenase activity
MAG.T21.45_01966	1122179.KB890449_gene132	9e-205	721.5	Sphingobacteriia			3.1.4.46,3.2.1.8	ko:K01126,ko:K01181	ko00564,map00564		R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000				Bacteria	1IPFX@117747,4NJ47@976,COG3291@1,COG3291@2	NA|NA|NA	N	C-terminal domain of CHU protein family
MAG.T21.45_01971	1122179.KB890449_gene132	1.4e-50	208.8	Sphingobacteriia			3.1.4.46,3.2.1.8	ko:K01126,ko:K01181	ko00564,map00564		R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000				Bacteria	1IPFX@117747,4NJ47@976,COG3291@1,COG3291@2	NA|NA|NA	N	C-terminal domain of CHU protein family
MAG.T21.45_01972	760192.Halhy_5638	4.2e-112	411.8	Bacteria				ko:K20543					ko00000,ko02000	1.B.55.3			Bacteria	COG4783@1,COG4783@2	NA|NA|NA	L	chaperone-mediated protein folding
MAG.T21.45_01973	760192.Halhy_5639	0.0	1140.6	Sphingobacteriia	gyrA		5.99.1.3	ko:K02469,ko:K02621					ko00000,ko01000,ko02048,ko03032,ko03036,ko03400				Bacteria	1IQJH@117747,4NDWQ@976,COG0188@1,COG0188@2	NA|NA|NA	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MAG.T21.45_01974	1313421.JHBV01000043_gene3042	2.3e-75	288.9	Sphingobacteriia	menG		2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQ48@117747,4NEDR@976,COG0500@1,COG2226@2	NA|NA|NA	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MAG.T21.45_01975	760192.Halhy_6315	2e-76	292.4	Sphingobacteriia	porT												Bacteria	1ISMS@117747,2C52N@1,2Z7U1@2,4NEZW@976	NA|NA|NA	S	Outer membrane protein beta-barrel domain
MAG.T21.45_01976	865937.Gilli_0741	1.1e-32	146.7	Gillisia	acpH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0008770,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0032787,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:0140096,GO:1901576	3.1.4.14	ko:K08682	ko00770,map00770		R01623		ko00000,ko00001,ko01000			iAPECO1_1312.APECO1_1606,iE2348C_1286.E2348C_0339,iECNA114_1301.ECNA114_0381,iECOK1_1307.ECOK1_0384,iECS88_1305.ECS88_0399,iECSF_1327.ECSF_0364,iPC815.YPO3193,iUMN146_1321.UM146_15340,iUTI89_1310.UTI89_C0426	Bacteria	1I1CI@117743,2P6KS@244698,4NHQK@976,COG3124@1,COG3124@2	NA|NA|NA	S	Acyl carrier protein phosphodiesterase
MAG.T21.45_01977	760192.Halhy_6082	1e-156	559.7	Sphingobacteriia	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464		ko:K06942					ko00000,ko03009				Bacteria	1IPTY@117747,4NF7N@976,COG0012@1,COG0012@2	NA|NA|NA	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MAG.T21.45_01978	504472.Slin_5650	3.5e-145	521.9	Cytophagia			1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000				Bacteria	47MET@768503,4NI42@976,COG2303@1,COG2303@2	NA|NA|NA	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MAG.T21.45_01979	760192.Halhy_5524	6.2e-259	901.4	Sphingobacteriia													Bacteria	1IPAB@117747,4NF7F@976,COG2911@1,COG2911@2	NA|NA|NA	S	TamB, inner membrane protein subunit of TAM complex
MAG.T21.45_01980	760192.Halhy_5257	4.4e-69	268.5	Bacteroidetes				ko:K07019					ko00000				Bacteria	4NFGZ@976,COG0429@1,COG0429@2	NA|NA|NA	S	hydrolase of the alpha beta-hydrolase fold
MAG.T21.45_01981	760192.Halhy_4829	8e-85	320.5	Sphingobacteriia	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPC6@117747,4NEYJ@976,COG0294@1,COG0294@2	NA|NA|NA	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MAG.T21.45_01982	760192.Halhy_4827	2.7e-48	198.7	Bacteroidetes	narL												Bacteria	4NN2R@976,COG2197@1,COG2197@2	NA|NA|NA	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MAG.T21.45_01983	761193.Runsl_3481	1.7e-145	523.5	Cytophagia													Bacteria	47K3W@768503,4PKVH@976,COG1629@1,COG1629@2	NA|NA|NA	P	PFAM TonB-dependent Receptor Plug
MAG.T21.45_01984	1122176.KB903538_gene1495	1e-14	88.6	Sphingobacteriia	ratA												Bacteria	1IZPT@117747,4PPJ6@976,COG1388@1,COG1388@2	NA|NA|NA	M	Lysin motif
MAG.T21.45_01985	1122176.KB903609_gene5227	8.4e-57	227.3	Sphingobacteriia				ko:K07001					ko00000				Bacteria	1ISRT@117747,4NERH@976,COG1752@1,COG1752@2	NA|NA|NA	S	esterase of the alpha-beta hydrolase superfamily
MAG.T21.45_01986	1519464.HY22_07225	2.5e-307	1061.6	Bacteria													Bacteria	COG1629@1,COG4771@2	NA|NA|NA	P	transport
MAG.T21.45_01987	760192.Halhy_4853	6.6e-80	304.3	Sphingobacteriia													Bacteria	1IQ05@117747,4NFG3@976,COG4874@1,COG4874@2	NA|NA|NA	S	Amidinotransferase
MAG.T21.45_01988	926549.KI421517_gene1568	2.1e-31	141.7	Cytophagia	yciH	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K03113	ko03013,map03013				ko00000,ko00001,ko03012				Bacteria	47R38@768503,4NS6M@976,COG0023@1,COG0023@2	NA|NA|NA	J	PFAM translation initiation factor SUI1
MAG.T21.45_01989	760192.Halhy_5832	8.9e-206	723.4	Sphingobacteriia	hscA	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010467,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051604,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070417,GO:0070887,GO:0071310,GO:0071704,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0097428,GO:0140110,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1903506,GO:1990230,GO:1990234,GO:2001141		ko:K04043,ko:K04044	ko03018,ko04212,ko05152,map03018,map04212,map05152				ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33,1.A.33.1			Bacteria	1IQ1C@117747,4NEHZ@976,COG0443@1,COG0443@2	NA|NA|NA	O	heat shock protein 70
MAG.T21.45_01990	1122176.KB903562_gene3431	9e-94	350.1	Sphingobacteriia	CP_0807			ko:K09125					ko00000				Bacteria	1IQJP@117747,4NFP3@976,COG1738@1,COG1738@2	NA|NA|NA	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MAG.T21.45_01991	760192.Halhy_0277	2.3e-52	213.0	Sphingobacteriia													Bacteria	1ISCP@117747,28HHD@1,2Z7T3@2,4NGWB@976	NA|NA|NA	S	Protein of unknown function (DUF3810)
MAG.T21.45_01992	1122179.KB890497_gene2804	5.3e-37	160.2	Sphingobacteriia	trxA			ko:K03671	ko04621,ko05418,map04621,map05418				ko00000,ko00001,ko03110				Bacteria	1ISZS@117747,4NQ5B@976,COG3118@1,COG3118@2	NA|NA|NA	O	Belongs to the thioredoxin family
MAG.T21.45_01993	760192.Halhy_0279	1.1e-119	436.4	Sphingobacteriia													Bacteria	1IRJS@117747,4NG0C@976,COG1721@1,COG1721@2	NA|NA|NA	S	protein (some members contain a von Willebrand factor type A (vWA) domain)
MAG.T21.45_01994	760192.Halhy_0282	4.3e-39	167.5	Sphingobacteriia	hslR	GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	5.4.99.23,5.4.99.24	ko:K04762,ko:K06179,ko:K06180					ko00000,ko01000,ko03009,ko03110				Bacteria	1ISBI@117747,4NP8I@976,COG1188@1,COG1188@2	NA|NA|NA	J	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MAG.T21.45_01995	1122176.KB903531_gene2832	8.7e-64	250.8	Sphingobacteriia													Bacteria	1IRUJ@117747,28P29@1,2ZBYD@2,4NMK6@976	NA|NA|NA		
MAG.T21.45_01996	760192.Halhy_0861	5.8e-160	570.5	Sphingobacteriia		GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K07114					ko00000,ko02000	1.A.13.2.2,1.A.13.2.3			Bacteria	1INMN@117747,4NFMA@976,COG4867@1,COG4867@2	NA|NA|NA	S	von Willebrand factor, type A
MAG.T21.45_01997	760192.Halhy_0860	4.5e-57	227.6	Bacteroidetes			1.11.1.15,2.7.13.3	ko:K03564,ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	4P4YA@976,COG1225@1,COG1225@2	NA|NA|NA	O	AhpC/TSA family
MAG.T21.45_01998	1122176.KB903554_gene4012	1.4e-135	489.2	Sphingobacteriia	mdh		1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000				Bacteria	1IP11@117747,4NEJ7@976,COG0039@1,COG0039@2	NA|NA|NA	C	Catalyzes the reversible oxidation of malate to oxaloacetate
MAG.T21.45_01999	1122176.KB903554_gene4014	4e-63	249.2	Bacteria													Bacteria	COG1572@1,COG1572@2	NA|NA|NA	NU	bacterial-type flagellum-dependent cell motility
MAG.T21.45_02000	760192.Halhy_0089	6.1e-190	672.5	Bacteroidetes													Bacteria	4NEZQ@976,COG4447@1,COG4447@2	NA|NA|NA	DZ	Hep Hag repeat protein
MAG.T21.45_02001	864073.HFRIS_012469	3.5e-36	159.1	Bacteria													Bacteria	COG0463@1,COG0463@2	NA|NA|NA	M	Glycosyl transferase, family 2
MAG.T21.45_02002	926562.Oweho_3300	1e-148	533.1	Cryomorphaceae	wecB		5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1HXDA@117743,2PBEZ@246874,4NGBD@976,COG0381@1,COG0381@2	NA|NA|NA	M	UDP-N-acetylglucosamine 2-epimerase
MAG.T21.45_02003	869213.JCM21142_93667	1.9e-34	153.3	Cytophagia													Bacteria	47SJI@768503,4NKAZ@976,COG1216@1,COG1216@2	NA|NA|NA	S	Glycosyltransferase like family 2
MAG.T21.45_02004	1122176.KB903609_gene5217	3.9e-81	309.3	Sphingobacteriia													Bacteria	1IP87@117747,4NEE5@976,COG4485@1,COG4485@2	NA|NA|NA	S	Bacterial membrane protein YfhO
MAG.T21.45_02005	376686.Fjoh_0345	7.5e-130	470.7	Flavobacteriia													Bacteria	1I2EC@117743,4NIX1@976,COG2244@1,COG2244@2	NA|NA|NA	S	Polysaccharide biosynthesis protein
MAG.T21.45_02006	468059.AUHA01000002_gene1154	2.1e-97	363.2	Sphingobacteriia													Bacteria	1IUXP@117747,29SIY@1,30DQ4@2,4NE5P@976	NA|NA|NA	S	Capsule assembly protein Wzi
MAG.T21.45_02007	468059.AUHA01000002_gene1154	5.9e-92	345.1	Sphingobacteriia													Bacteria	1IUXP@117747,29SIY@1,30DQ4@2,4NE5P@976	NA|NA|NA	S	Capsule assembly protein Wzi
MAG.T21.45_02008	290512.Paes_0204	1.1e-46	193.4	Bacteria				ko:K20333	ko02024,map02024				ko00000,ko00001				Bacteria	COG1262@1,COG1262@2,COG1680@1,COG1680@2	NA|NA|NA	T	PFAM Formylglycine-generating sulfatase enzyme
MAG.T21.45_02009	641524.ADICYQ_3615	1.3e-119	436.8	Cytophagia				ko:K03307					ko00000	2.A.21			Bacteria	47TSV@768503,4P15S@976,COG0591@1,COG0591@2	NA|NA|NA	E	Sodium:solute symporter family
MAG.T21.45_02011	1123248.KB893318_gene4121	1.1e-88	333.2	Sphingobacteriia													Bacteria	1IVSN@117747,4NHVK@976,COG1028@1,COG1028@2	NA|NA|NA	IQ	KR domain
MAG.T21.45_02012	880070.Cycma_4969	8.3e-178	629.8	Cytophagia	MA20_16885												Bacteria	47JK9@768503,4NKJ1@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_02013	760192.Halhy_3735	1.4e-102	379.4	Sphingobacteriia	MA20_16875											iECBD_1354.ECBD_3826,iECB_1328.ECB_04075,iECS88_1305.ECS88_4797	Bacteria	1IWGQ@117747,4NHJE@976,COG1082@1,COG1082@2	NA|NA|NA	G	Xylose isomerase-like TIM barrel
MAG.T21.45_02014	929562.Emtol_1151	2e-194	685.3	Cytophagia													Bacteria	47MFS@768503,4NJYK@976,COG4225@1,COG4225@2	NA|NA|NA	S	Glycosyl Hydrolase Family 88
MAG.T21.45_02015	929562.Emtol_0722	2.8e-96	358.6	Cytophagia													Bacteria	47NJ6@768503,4NJ3Z@976,COG1082@1,COG1082@2	NA|NA|NA	G	Xylose isomerase domain protein TIM barrel
MAG.T21.45_02016	760192.Halhy_1942	8.3e-78	297.0	Sphingobacteriia													Bacteria	1IPN9@117747,4NEAI@976,COG1028@1,COG1028@2	NA|NA|NA	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)
MAG.T21.45_02017	760192.Halhy_0613	1.5e-54	219.5	Sphingobacteriia													Bacteria	1IXSM@117747,2E0SZ@1,32WAT@2,4NIDB@976	NA|NA|NA	S	Protein of unknown function (DUF2490)
MAG.T21.45_02018	485918.Cpin_1834	5.9e-70	271.6	Sphingobacteriia													Bacteria	1INSA@117747,4NEX3@976,COG0526@1,COG0526@2	NA|NA|NA	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MAG.T21.45_02020	880070.Cycma_2707	9.8e-76	290.4	Cytophagia			3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110		GH20		Bacteria	47N9K@768503,4NKFY@976,COG1082@1,COG1082@2	NA|NA|NA	G	Xylose isomerase domain protein TIM barrel
MAG.T21.45_02021	760192.Halhy_6147	2.2e-227	795.0	Sphingobacteriia	pepP	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9	ko:K01262					ko00000,ko01000,ko01002				Bacteria	1IWD5@117747,4NI0S@976,COG0006@1,COG0006@2	NA|NA|NA	E	Aminopeptidase P, N-terminal domain
MAG.T21.45_02022	485917.Phep_0776	5.4e-181	640.6	Sphingobacteriia				ko:K02429					ko00000,ko02000	2.A.1.7			Bacteria	1IR81@117747,4NEYR@976,COG0738@1,COG0738@2	NA|NA|NA	G	glucose galactose transporter
MAG.T21.45_02023	1288963.ADIS_2850	2e-106	392.5	Cytophagia													Bacteria	47MBN@768503,4NHFK@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_02024	485917.Phep_0778	3.5e-155	554.7	Sphingobacteriia			3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130		R02059	RC00166,RC00300	ko00000,ko00001,ko01000				Bacteria	1IPWP@117747,4NJ35@976,COG1820@1,COG1820@2	NA|NA|NA	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MAG.T21.45_02025	761193.Runsl_2608	2.3e-88	332.0	Cytophagia	nagB		3.1.1.31,3.5.99.6	ko:K01057,ko:K02564	ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000				Bacteria	47PHR@768503,4NFCM@976,COG0363@1,COG0363@2	NA|NA|NA	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
MAG.T21.45_02026	1123248.KB893370_gene5011	1.9e-121	442.6	Sphingobacteriia													Bacteria	1IQII@117747,4NGKU@976,COG4299@1,COG4299@2	NA|NA|NA	S	COGs COG4299 conserved
MAG.T21.45_02027	762903.Pedsa_0739	1.8e-192	678.7	Sphingobacteriia													Bacteria	1IQ5B@117747,4NF96@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase domain protein
MAG.T21.45_02028	927658.AJUM01000037_gene2109	1.3e-14	86.7	Bacteroidetes													Bacteria	2C5RI@1,333DB@2,4NV7H@976	NA|NA|NA		
MAG.T21.45_02029	1270196.JCKI01000002_gene383	1.1e-150	540.4	Sphingobacteriia													Bacteria	1IPTZ@117747,4NH7Q@976,COG5492@1,COG5492@2	NA|NA|NA	N	domain, Protein
MAG.T21.45_02030	761193.Runsl_2017	3.9e-261	907.9	Cytophagia													Bacteria	47JSW@768503,4NEIE@976,COG1629@1,COG4771@2	NA|NA|NA	P	PFAM TonB-dependent Receptor Plug
MAG.T21.45_02031	1233951.IO90_05030	2.5e-25	120.9	Flavobacteriia													Bacteria	1I5HN@117743,2DNM0@1,32Y1X@2,4NWJ4@976	NA|NA|NA		
MAG.T21.45_02032	1233951.IO90_05025	1.5e-57	228.8	Flavobacteriia	vapC												Bacteria	1I1PD@117743,4NNGQ@976,COG1848@1,COG1848@2	NA|NA|NA	S	PIN domain
MAG.T21.45_02034	760192.Halhy_4547	3.8e-124	451.8	Sphingobacteriia													Bacteria	1IQCY@117747,4NF9W@976,COG0671@1,COG0671@2	NA|NA|NA	I	Phosphoesterase PA-phosphatase related
MAG.T21.45_02035	641524.ADICYQ_0562	1.5e-74	286.6	Cytophagia													Bacteria	47Y9R@768503,4PKDQ@976,COG0657@1,COG0657@2	NA|NA|NA	I	Carboxylesterase family
MAG.T21.45_02036	760192.Halhy_6547	1.5e-267	928.7	Sphingobacteriia	nagB		3.1.1.31,3.5.99.6	ko:K01057,ko:K02080,ko:K02564	ko00030,ko00052,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00052,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035,R08365	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPSI@117747,4NDUN@976,COG0363@1,COG0363@2,COG2120@1,COG2120@2	NA|NA|NA	G	Glucosamine-6-phosphate
MAG.T21.45_02037	760192.Halhy_6546	1.2e-196	693.3	Sphingobacteriia			3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110		GH20		Bacteria	1IPND@117747,4NE08@976,COG3525@1,COG3525@2	NA|NA|NA	G	Glycosyl hydrolase family 20, catalytic domain
MAG.T21.45_02038	1189612.A33Q_2611	1.8e-227	795.4	Cytophagia	putP												Bacteria	47MV2@768503,4PKHI@976,COG0591@1,COG0591@2	NA|NA|NA	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MAG.T21.45_02039	760192.Halhy_6498	5.8e-208	731.1	Sphingobacteriia	fixI	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016		R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5			Bacteria	1IPQU@117747,4NEI1@976,COG2217@1,COG2217@2,COG2608@1,COG2608@2	NA|NA|NA	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC
MAG.T21.45_02040	760192.Halhy_0010	0.0	1259.6	Sphingobacteriia	ccoO	GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600	1.9.3.1	ko:K00404,ko:K00405,ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156			ko00000,ko00001,ko00002,ko01000	3.D.4.3		iIT341.HP0144,iIT341.HP0145	Bacteria	1IP6D@117747,4NEGM@976,COG2993@1,COG2993@2,COG3278@1,COG3278@2	NA|NA|NA	C	Belongs to the heme-copper respiratory oxidase family
MAG.T21.45_02042	760192.Halhy_0008	4.4e-78	298.1	Sphingobacteriia	ccoP			ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156			ko00000,ko00001,ko00002	3.D.4.3			Bacteria	1IRZW@117747,4NFMJ@976,COG2010@1,COG2010@2	NA|NA|NA	C	PFAM Cytochrome c, class I
MAG.T21.45_02043	1121904.ARBP01000002_gene7145	4.4e-144	518.1	Cytophagia	ccoG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944											Bacteria	47KT1@768503,4NFDN@976,COG0348@1,COG0348@2	NA|NA|NA	C	TIGRFAM cytochrome c oxidase accessory protein
MAG.T21.45_02044	760192.Halhy_0006	1.8e-19	102.4	Sphingobacteriia	fixH												Bacteria	1J13K@117747,4NUZC@976,COG5456@1,COG5456@2	NA|NA|NA	P	FixH
MAG.T21.45_02045	760192.Halhy_0005	4.7e-38	164.9	Sphingobacteriia	braZ			ko:K09792					ko00000				Bacteria	1ISVK@117747,4NF84@976,COG2836@1,COG2836@2	NA|NA|NA	S	Cytochrome C biogenesis protein transmembrane region
MAG.T21.45_02046	1122176.KB903547_gene1100	0.0	1371.7	Sphingobacteriia													Bacteria	1J0JI@117747,4NDXS@976,COG1629@1,COG1629@2,COG4771@2	NA|NA|NA	P	TonB dependent receptor
MAG.T21.45_02047	1122176.KB903547_gene1099	8e-178	630.2	Bacteroidetes				ko:K21572					ko00000,ko02000	8.A.46.1,8.A.46.3			Bacteria	4PMHA@976,COG3637@1,COG3637@2	NA|NA|NA	M	SusD family
MAG.T21.45_02048	1122176.KB903547_gene1098	1.7e-294	1018.8	Sphingobacteriia			3.4.21.96	ko:K01361,ko:K20276	ko02024,map02024				ko00000,ko00001,ko01000,ko01002,ko03110				Bacteria	1J0XS@117747,4PP23@976,COG4733@1,COG4733@2	NA|NA|NA	S	Concanavalin A-like lectin/glucanases superfamily
MAG.T21.45_02049	1122176.KB903547_gene1097	0.0	1416.4	Sphingobacteriia			3.2.1.18,3.2.1.82	ko:K01186,ko:K18650	ko00511,ko00600,ko04142,map00511,map00600,map04142		R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042		GH28,GH33		Bacteria	1IV35@117747,4NPYJ@976,COG4733@1,COG4733@2	NA|NA|NA	S	Concanavalin A-like lectin/glucanases superfamily
MAG.T21.45_02050	1122176.KB903547_gene1096	7.1e-139	500.4	Sphingobacteriia			2.4.1.339,2.4.1.340	ko:K20885			R11397,R11398	RC00049,RC02748	ko00000,ko01000		GH130		Bacteria	1IPMU@117747,4NGI7@976,COG2152@1,COG2152@2	NA|NA|NA	G	beta-1,4-mannooligosaccharide phosphorylase
MAG.T21.45_02051	1408473.JHXO01000011_gene3130	1.5e-151	542.7	Bacteroidia	yqgE			ko:K03762,ko:K08222					ko00000,ko02000	2.A.1.33,2.A.1.6.4			Bacteria	2G15G@200643,4NGD7@976,COG0477@1,COG0477@2	NA|NA|NA	EGP	Major facilitator Superfamily
MAG.T21.45_02052	1121012.AUKX01000010_gene2034	2.8e-164	585.5	Arenibacter													Bacteria	1I7N5@117743,23GT5@178469,2DBD9@1,2Z8J6@2,4NHNA@976	NA|NA|NA		
MAG.T21.45_02053	641524.ADICYQ_2258	0.0	1199.9	Cytophagia			3.6.3.8	ko:K01537					ko00000,ko01000	3.A.3.2			Bacteria	47JYI@768503,4NERM@976,COG0474@1,COG0474@2	NA|NA|NA	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC
MAG.T21.45_02054	1406840.Q763_14335	3.6e-84	318.5	Flavobacterium	yrbG			ko:K07301					ko00000,ko02000	2.A.19.5			Bacteria	1IC39@117743,2NY56@237,4NFBC@976,COG0530@1,COG0530@2	NA|NA|NA	P	Sodium/calcium exchanger protein
MAG.T21.45_02055	468059.AUHA01000003_gene1712	1.9e-296	1025.0	Sphingobacteriia	ppsA		2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000				Bacteria	1INV9@117747,4NEHE@976,COG0574@1,COG0574@2,COG1080@1,COG1080@2	NA|NA|NA	G	Belongs to the PEP-utilizing enzyme family
MAG.T21.45_02057	485917.Phep_2982	2.6e-16	92.8	Sphingobacteriia													Bacteria	1IXMS@117747,4NTZ2@976,COG2207@1,COG2207@2	NA|NA|NA	K	PFAM Bacterial regulatory helix-turn-helix proteins, AraC family
MAG.T21.45_02058	485917.Phep_2982	8.9e-26	124.8	Sphingobacteriia													Bacteria	1IXMS@117747,4NTZ2@976,COG2207@1,COG2207@2	NA|NA|NA	K	PFAM Bacterial regulatory helix-turn-helix proteins, AraC family
MAG.T21.45_02059	319224.Sputcn32_3550	7.5e-29	135.6	Shewanellaceae	oprH		3.1.3.8	ko:K01083,ko:K02014,ko:K16087	ko00562,map00562		R03371	RC00078	ko00000,ko00001,ko01000,ko02000	1.B.14,1.B.14.2			Bacteria	1MU7T@1224,1RNK8@1236,2QA62@267890,COG2931@1,COG2931@2,COG3637@1,COG3637@2	NA|NA|NA	MQ	Dystroglycan-type cadherin domain protein
MAG.T21.45_02061	760192.Halhy_0688	3e-40	171.4	Sphingobacteriia	CP_0991			ko:K07117					ko00000				Bacteria	1IYW5@117747,4P66M@976,COG2940@1,COG2940@2	NA|NA|NA	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
MAG.T21.45_02062	760192.Halhy_1161	9.9e-54	216.5	Sphingobacteriia	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141		ko:K03925					ko00000				Bacteria	1IY8G@117747,4NM4X@976,COG2001@1,COG2001@2	NA|NA|NA	K	MraZ protein, putative antitoxin-like
MAG.T21.45_02063	760192.Halhy_1160	8.8e-90	337.0	Sphingobacteriia	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438					ko00000,ko01000,ko03009				Bacteria	1INNA@117747,4NFQB@976,COG0275@1,COG0275@2	NA|NA|NA	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MAG.T21.45_02064	760192.Halhy_1159	8.6e-19	99.8	Sphingobacteriia													Bacteria	1ITVW@117747,2ADW1@1,313N1@2,4P9FS@976	NA|NA|NA		
MAG.T21.45_02065	760192.Halhy_1158	2.6e-212	745.3	Sphingobacteriia	ftsI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681	2.7.11.1,3.4.16.4	ko:K03587,ko:K08384,ko:K08724,ko:K12132,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501				ko00000,ko00001,ko01000,ko01001,ko01011,ko03036			iSSON_1240.SSON_0092	Bacteria	1IQ79@117747,4NERV@976,COG0768@1,COG0768@2,COG2815@1,COG2815@2	NA|NA|NA	M	Cell division protein FtsI penicillin-binding protein 2
MAG.T21.45_02066	760192.Halhy_1157	1.5e-155	556.2	Sphingobacteriia	murE		6.3.2.10,6.3.2.13	ko:K01928,ko:K15792	ko00300,ko00550,map00300,map00550		R02788,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	1INW4@117747,4NE9W@976,COG0769@1,COG0769@2	NA|NA|NA	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MAG.T21.45_02067	760192.Halhy_1156	2.7e-161	575.1	Sphingobacteriia	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502		R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146		iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Bacteria	1IQU9@117747,4NE0T@976,COG0472@1,COG0472@2	NA|NA|NA	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MAG.T21.45_02068	760192.Halhy_1155	3e-131	475.3	Sphingobacteriia	murD		6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100		R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	1INPJ@117747,4NEFF@976,COG0771@1,COG0771@2	NA|NA|NA	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MAG.T21.45_02069	760192.Halhy_1154	3.3e-121	441.8	Sphingobacteriia	ftsW			ko:K03588	ko04112,map04112				ko00000,ko00001,ko02000,ko03036	2.A.103.1			Bacteria	1IPWG@117747,4NFIM@976,COG0772@1,COG0772@2	NA|NA|NA	D	Belongs to the SEDS family
MAG.T21.45_02070	1122176.KB903576_gene4960	3.5e-107	395.2	Sphingobacteriia	murG	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.227,6.3.2.8	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112		R03193,R05032,R05662	RC00005,RC00049,RC00064,RC00141	ko00000,ko00001,ko01000,ko01011		GT28	iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089	Bacteria	1IPF4@117747,4NE6D@976,COG0707@1,COG0707@2	NA|NA|NA	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MAG.T21.45_02071	760192.Halhy_1152	7.5e-141	507.3	Sphingobacteriia	murC		6.3.2.4,6.3.2.8	ko:K01921,ko:K01924	ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502		R01150,R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	1INTF@117747,4NE1V@976,COG0773@1,COG0773@2	NA|NA|NA	M	Belongs to the MurCDEF family
MAG.T21.45_02072	760192.Halhy_1151	1.3e-52	213.4	Sphingobacteriia	ftsQ			ko:K03589	ko04112,map04112				ko00000,ko00001,ko03036				Bacteria	1IRV2@117747,4NGPN@976,COG1589@1,COG1589@2	NA|NA|NA	M	Cell division protein
MAG.T21.45_02073	760192.Halhy_1150	2.1e-177	628.6	Sphingobacteriia	ftsA	GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363		ko:K03590	ko04112,map04112				ko00000,ko00001,ko03036,ko04812				Bacteria	1IQJQ@117747,4NE0V@976,COG0849@1,COG0849@2	NA|NA|NA	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MAG.T21.45_02074	1122176.KB903576_gene4964	2.7e-168	598.6	Sphingobacteriia	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363		ko:K03531	ko04112,map04112				ko00000,ko00001,ko02048,ko03036,ko04812				Bacteria	1IR5B@117747,4NF8N@976,COG0206@1,COG0206@2	NA|NA|NA	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MAG.T21.45_02076	1034807.FBFL15_2692	8.1e-250	869.8	Flavobacterium			3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	1HWYD@117743,2NSEZ@237,4NDWN@976,COG0210@1,COG0210@2	NA|NA|NA	L	Helicase
MAG.T21.45_02077	1034807.FBFL15_0837	9.9e-34	149.8	Flavobacterium	dam		2.1.1.72	ko:K06223,ko:K07318	ko03430,map03430				ko00000,ko00001,ko01000,ko02048,ko03032,ko03400				Bacteria	1HZED@117743,2NYFR@237,4NIHU@976,COG3392@1,COG3392@2	NA|NA|NA	L	D12 class N6 adenine-specific DNA methyltransferase
MAG.T21.45_02080	1034807.FBFL15_0836	5.8e-192	676.8	Flavobacterium													Bacteria	1II8P@117743,28HP3@1,2NYN7@237,2Z7X8@2,4NKF8@976	NA|NA|NA		
MAG.T21.45_02081	1034807.FBFL15_0837	1.5e-169	602.1	Flavobacterium	dam		2.1.1.72	ko:K06223,ko:K07318	ko03430,map03430				ko00000,ko00001,ko01000,ko02048,ko03032,ko03400				Bacteria	1HZED@117743,2NYFR@237,4NIHU@976,COG3392@1,COG3392@2	NA|NA|NA	L	D12 class N6 adenine-specific DNA methyltransferase
MAG.T21.45_02084	1120966.AUBU01000001_gene1173	0.0	1170.2	Cytophagia													Bacteria	47M35@768503,4NDU8@976,COG1629@1,COG4771@2	NA|NA|NA	P	PFAM TonB-dependent Receptor Plug
MAG.T21.45_02085	1120966.AUBU01000001_gene1174	1.2e-198	699.5	Cytophagia													Bacteria	47JVY@768503,4PKAT@976,COG0521@1,COG0521@2	NA|NA|NA	H	Starch-binding associating with outer membrane
MAG.T21.45_02086	926549.KI421517_gene1088	1e-297	1029.6	Cytophagia													Bacteria	47N6G@768503,4NEE8@976,COG4888@1,COG4888@2	NA|NA|NA	S	ASPIC and UnbV
MAG.T21.45_02087	926549.KI421517_gene1087	5.1e-107	394.8	Cytophagia													Bacteria	47JAV@768503,4NF9W@976,COG0671@1,COG0671@2	NA|NA|NA	I	PAP2 superfamily
MAG.T21.45_02088	1305737.JAFX01000001_gene55	8e-17	95.1	Cytophagia													Bacteria	47TA7@768503,4NTZ2@976,COG2207@1,COG2207@2	NA|NA|NA	K	Helix-turn-helix domain
MAG.T21.45_02089	929562.Emtol_4065	1.4e-38	166.4	Cytophagia													Bacteria	2DVGX@1,33VUC@2,47UX8@768503,4P36S@976	NA|NA|NA		
MAG.T21.45_02090	946077.W5A_08442	1.9e-46	191.8	Flavobacteriia				ko:K09922					ko00000				Bacteria	1I2VM@117743,4NQH4@976,COG3169@1,COG3169@2	NA|NA|NA	S	Putative member of DMT superfamily (DUF486)
MAG.T21.45_02091	1313421.JHBV01000029_gene1873	1e-15	90.9	Sphingobacteriia													Bacteria	1IXHW@117747,4PHX4@976,COG3291@1,COG3291@2	NA|NA|NA	N	Pkd domain containing protein
MAG.T21.45_02092	504487.JCM19302_2169	5.3e-40	171.4	Flavobacteriia													Bacteria	1I4Y5@117743,2DICN@1,32UAX@2,4NU78@976	NA|NA|NA		
MAG.T21.45_02093	1178825.ALIH01000005_gene159	9.6e-120	437.2	Flavobacteriia													Bacteria	1HY2C@117743,4NJKZ@976,COG4102@1,COG4102@2	NA|NA|NA	S	Protein of unknown function (DUF1501)
MAG.T21.45_02094	1178825.ALIH01000005_gene158	8.6e-121	441.0	Flavobacteriia													Bacteria	1I0QW@117743,4NJBN@976,COG5267@1,COG5267@2	NA|NA|NA	S	Protein of unknown function (DUF1800)
MAG.T21.45_02095	1250232.JQNJ01000001_gene3848	3.5e-17	96.7	Flavobacteriia													Bacteria	1HZFE@117743,4NDXU@976,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
MAG.T21.45_02096	1048983.EL17_12050	1.3e-12	80.9	Cytophagia				ko:K07011					ko00000				Bacteria	47N66@768503,4NH8F@976,COG3206@1,COG3206@2	NA|NA|NA	M	lipopolysaccharide biosynthesis protein
MAG.T21.45_02097	1122179.KB890424_gene3578	8.2e-74	285.4	Sphingobacteriia				ko:K01991	ko02026,map02026				ko00000,ko00001,ko02000	1.B.18			Bacteria	1IPNG@117747,4NEXJ@976,COG1596@1,COG1596@2	NA|NA|NA	M	export protein
MAG.T21.45_02098	760192.Halhy_2622	3.7e-128	464.5	Sphingobacteriia	mak		2.7.1.4,2.7.1.59	ko:K00847,ko:K00884	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100		R00760,R00867,R01201,R03920	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	1IURS@117747,4NGC1@976,COG1940@1,COG1940@2	NA|NA|NA	GK	COGs COG1940 Transcriptional regulator sugar kinase
MAG.T21.45_02099	760192.Halhy_2623	5.3e-108	398.3	Sphingobacteriia	pepA		3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100		R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002				Bacteria	1IVT9@117747,4NDWT@976,COG0260@1,COG0260@2	NA|NA|NA	E	Belongs to the peptidase M17 family
MAG.T21.45_02100	1089547.KB913013_gene323	3.1e-182	644.8	Cytophagia	baeB		3.1.2.6,3.4.21.102	ko:K01069,ko:K03797	ko00620,map00620		R01736	RC00004,RC00137	ko00000,ko00001,ko01000,ko01002				Bacteria	47MX5@768503,4NE2Y@976,COG0491@1,COG0491@2,COG0607@1,COG0607@2	NA|NA|NA	P	Zn-dependent hydrolase
MAG.T21.45_02101	760192.Halhy_2070	1.6e-149	536.6	Sphingobacteriia													Bacteria	1IPCG@117747,4NE6G@976,COG0457@1,COG0457@2,COG0823@1,COG0823@2,COG2885@1,COG2885@2	NA|NA|NA	MU	Belongs to the ompA family
MAG.T21.45_02102	760192.Halhy_2808	5.6e-175	620.5	Sphingobacteriia	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQYP@117747,4NGRZ@976,COG0104@1,COG0104@2	NA|NA|NA	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MAG.T21.45_02103	760192.Halhy_3220	1.9e-60	238.8	Sphingobacteriia	dapH												Bacteria	1IS18@117747,4NG6R@976,COG0663@1,COG0663@2	NA|NA|NA	S	COGs COG0663 Carbonic anhydrase acetyltransferase isoleucine patch superfamily
MAG.T21.45_02104	760192.Halhy_3447	3.7e-140	505.0	Sphingobacteriia	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.98.3	ko:K02495	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R06895	RC00884	ko00000,ko00001,ko00002,ko01000			iECIAI39_1322.ECIAI39_3134,iZ_1308.Z5403	Bacteria	1IPSZ@117747,4NEY5@976,COG0635@1,COG0635@2	NA|NA|NA	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family
MAG.T21.45_02105	760192.Halhy_2606	1.4e-55	223.4	Sphingobacteriia													Bacteria	1IU6A@117747,4NER9@976,COG0589@1,COG0589@2	NA|NA|NA	T	Universal stress protein family
MAG.T21.45_02106	760192.Halhy_2916	1.6e-97	362.8	Bacteroidetes	aphA												Bacteria	4NF3X@976,COG0123@1,COG0123@2	NA|NA|NA	BQ	including yeast histone deacetylase and acetoin utilization protein
MAG.T21.45_02107	391598.FBBAL38_11469	1.2e-25	124.0	Flavobacteriia													Bacteria	1I4NQ@117743,4NTMP@976,COG4704@1,COG4704@2,COG5295@1,COG5295@2	NA|NA|NA	UW	Hep Hag repeat protein
MAG.T21.45_02108	762903.Pedsa_2028	2e-20	107.1	Sphingobacteriia													Bacteria	1IXMS@117747,4NTZ2@976,COG2207@1,COG2207@2	NA|NA|NA	K	PFAM Bacterial regulatory helix-turn-helix proteins, AraC family
MAG.T21.45_02109	760192.Halhy_2491	2e-66	258.8	Sphingobacteriia	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360		ko:K03553	ko03440,map03440	M00729			ko00000,ko00001,ko00002,ko03400				Bacteria	1INW2@117747,4NEXT@976,COG0468@1,COG0468@2	NA|NA|NA	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MAG.T21.45_02110	760192.Halhy_3038	6.2e-159	567.4	Sphingobacteriia	rumA		2.1.1.190	ko:K03215					ko00000,ko01000,ko03009				Bacteria	1IQPD@117747,4NFP1@976,COG2265@1,COG2265@2	NA|NA|NA	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MAG.T21.45_02111	760192.Halhy_3039	1.8e-27	128.6	Sphingobacteriia													Bacteria	1ISYI@117747,2BXI1@1,32R1C@2,4NR9I@976	NA|NA|NA		
MAG.T21.45_02112	760192.Halhy_3040	3.9e-23	114.4	Sphingobacteriia													Bacteria	1IZUX@117747,4PK0R@976,COG0745@1,COG0745@2	NA|NA|NA	T	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MAG.T21.45_02113	1122176.KB903542_gene430	3.4e-131	474.6	Sphingobacteriia	rfbA	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv0334	Bacteria	1IPV3@117747,4NE1U@976,COG1209@1,COG1209@2	NA|NA|NA	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MAG.T21.45_02114	1123248.KB893321_gene543	2.4e-193	682.6	Sphingobacteriia				ko:K16089					ko00000,ko02000	1.B.14.1,1.B.14.10			Bacteria	1IP85@117747,4NE7A@976,COG1629@1,COG2608@1,COG2608@2,COG4771@2	NA|NA|NA	P	TonB-dependent receptor
MAG.T21.45_02115	888059.HMPREF9071_0703	8.9e-46	190.3	Capnocytophaga	ddpX	GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009046,GO:0009605,GO:0009991,GO:0016787,GO:0019538,GO:0031667,GO:0042594,GO:0043170,GO:0044238,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.13.22	ko:K07282,ko:K08641	ko01502,ko02020,map01502,map02020	M00651			ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504				Bacteria	1EQFD@1016,1I1V9@117743,4NE2K@976,COG2173@1,COG2173@2	NA|NA|NA	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MAG.T21.45_02116	929562.Emtol_3851	1.4e-84	319.7	Cytophagia	lipG												Bacteria	47R8C@768503,4NTHK@976,COG2267@1,COG2267@2	NA|NA|NA	I	Serine aminopeptidase, S33
MAG.T21.45_02117	1443665.JACA01000006_gene71	1.8e-09	69.7	Aquimarina													Bacteria	1I1PP@117743,2DBMF@1,2YJ1F@290174,2Z9YG@2,4NPRW@976	NA|NA|NA		
MAG.T21.45_02118	760192.Halhy_2123	1.1e-78	300.4	Sphingobacteriia	mltD			ko:K08307,ko:K12204					ko00000,ko01000,ko01011,ko02044	3.A.7.10.1,3.A.7.9.1			Bacteria	1IRNH@117747,4NEKW@976,COG0741@1,COG0741@2,COG1388@1,COG1388@2	NA|NA|NA	M	PFAM Transglycosylase SLT domain
MAG.T21.45_02119	1122176.KB903534_gene2070	1.6e-63	249.6	Sphingobacteriia	murI	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100		R00260	RC00302	ko00000,ko00001,ko01000,ko01011				Bacteria	1IPZH@117747,4NG1C@976,COG0796@1,COG0796@2	NA|NA|NA	M	Provides the (R)-glutamate required for cell wall biosynthesis
MAG.T21.45_02120	1122179.KB890413_gene4670	6.4e-37	160.6	Sphingobacteriia	ompH			ko:K06142					ko00000				Bacteria	1ITN8@117747,4NSCM@976,COG2825@1,COG2825@2	NA|NA|NA	M	PFAM outer membrane chaperone Skp (OmpH)
MAG.T21.45_02121	760192.Halhy_3183	1.7e-51	209.1	Sphingobacteriia	ompH			ko:K06142					ko00000				Bacteria	1IS3M@117747,4NH46@976,COG2825@1,COG2825@2	NA|NA|NA	M	outer membrane chaperone Skp (OmpH)
MAG.T21.45_02122	760192.Halhy_3186	6.1e-56	224.2	Sphingobacteriia			3.6.1.27	ko:K12977,ko:K19302	ko00550,map00550		R05627	RC00002	ko00000,ko00001,ko01000,ko01005,ko01011				Bacteria	1IUI6@117747,4NUPJ@976,COG0671@1,COG0671@2	NA|NA|NA	I	phosphoesterase, PA-phosphatase related
MAG.T21.45_02123	760192.Halhy_3432	5e-76	292.0	Bacteria													Bacteria	COG0457@1,COG0457@2,COG2304@1,COG2304@2	NA|NA|NA	IU	oxidoreductase activity
MAG.T21.45_02124	760192.Halhy_2919	1.7e-145	522.3	Sphingobacteriia	thiL		2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000			iYO844.BSU05900	Bacteria	1IQ84@117747,4NDUT@976,COG0611@1,COG0611@2	NA|NA|NA	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MAG.T21.45_02125	760192.Halhy_2944	4e-112	411.4	Sphingobacteriia	ywaD												Bacteria	1IS59@117747,4NG2A@976,COG2234@1,COG2234@2	NA|NA|NA	S	Peptidase family M28
MAG.T21.45_02126	1121897.AUGO01000008_gene2740	8e-52	211.8	Bacteroidetes													Bacteria	4NKVZ@976,COG0457@1,COG0457@2,COG2207@1,COG2207@2	NA|NA|NA	K	helix_turn_helix, arabinose operon control protein
MAG.T21.45_02127	760192.Halhy_3443	3.8e-143	515.0	Sphingobacteriia	hipB			ko:K07110,ko:K22299					ko00000,ko03000				Bacteria	1IWMC@117747,4NDVH@976,COG1396@1,COG1396@2,COG3800@1,COG3800@2	NA|NA|NA	K	Helix-turn-helix XRE-family like proteins
MAG.T21.45_02128	760192.Halhy_3444	1.2e-236	826.2	Sphingobacteriia	dpp		3.4.14.5	ko:K01278	ko04974,map04974				ko00000,ko00001,ko01000,ko01002,ko04090,ko04147				Bacteria	1IR71@117747,4NETS@976,COG0823@1,COG0823@2,COG1506@1,COG1506@2	NA|NA|NA	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region
MAG.T21.45_02129	760192.Halhy_3445	1e-47	196.4	Sphingobacteriia	smpB	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564		ko:K03664					ko00000				Bacteria	1ISGQ@117747,4NNJU@976,COG0691@1,COG0691@2	NA|NA|NA	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MAG.T21.45_02130	760192.Halhy_3457	3.1e-120	438.3	Sphingobacteriia	galE		5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000				Bacteria	1INXE@117747,4NEM9@976,COG1087@1,COG1087@2	NA|NA|NA	M	PFAM NAD dependent epimerase dehydratase family
MAG.T21.45_02131	760192.Halhy_3456	2.3e-73	282.3	Sphingobacteriia	cysQ		3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130		R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016				Bacteria	1ISXY@117747,4NFHY@976,COG1218@1,COG1218@2	NA|NA|NA	P	COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase
MAG.T21.45_02132	760192.Halhy_3250	1.9e-175	622.1	Sphingobacteriia	cat2		3.1.2.1	ko:K01067	ko00620,map00620		R00227	RC00004,RC00012	ko00000,ko00001,ko01000				Bacteria	1IPAZ@117747,4NFS3@976,COG0427@1,COG0427@2	NA|NA|NA	C	acetyl-CoA hydrolase
MAG.T21.45_02134	760192.Halhy_3097	4.4e-81	307.8	Sphingobacteriia				ko:K02014					ko00000,ko02000	1.B.14			Bacteria	1J0MG@117747,4PN7E@976,COG1629@1,COG4771@2	NA|NA|NA	P	CarboxypepD_reg-like domain
MAG.T21.45_02135	760192.Halhy_3275	1.1e-307	1062.4	Sphingobacteriia	lon		3.4.21.53	ko:K01338	ko04112,map04112				ko00000,ko00001,ko01000,ko01002				Bacteria	1IQDQ@117747,4NE1G@976,COG0466@1,COG0466@2	NA|NA|NA	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MAG.T21.45_02136	760192.Halhy_2067	7.3e-272	943.0	Sphingobacteriia	parE		5.99.1.3	ko:K02470,ko:K02622					ko00000,ko01000,ko02048,ko03032,ko03036,ko03400				Bacteria	1IQV0@117747,4NF18@976,COG0187@1,COG0187@2	NA|NA|NA	L	Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit
MAG.T21.45_02137	1408473.JHXO01000010_gene3757	2.2e-113	416.0	Bacteroidia													Bacteria	2FS76@200643,4NE6S@976,COG0438@1,COG0438@2	NA|NA|NA	M	glycosyl transferase
MAG.T21.45_02138	760192.Halhy_3045	8.1e-103	380.6	Sphingobacteriia	ldcA		3.4.17.13	ko:K01297					ko00000,ko01000,ko01002,ko01011				Bacteria	1ISFK@117747,4NF5Q@976,COG1619@1,COG1619@2	NA|NA|NA	V	PFAM Peptidase S66, LD-carboxypeptidase A
MAG.T21.45_02139	1121481.AUAS01000003_gene4050	3.6e-116	424.9	Cytophagia	ykfB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802			R10938	RC03309	ko00000,ko01000				Bacteria	47K7T@768503,4NG8N@976,COG4948@1,COG4948@2	NA|NA|NA	M	mandelate racemase muconate lactonizing
MAG.T21.45_02140	760192.Halhy_2086	5.7e-72	278.1	Sphingobacteriia													Bacteria	1IS9B@117747,4NKC1@976,COG0156@1,COG0156@2	NA|NA|NA	H	PFAM Aminotransferase class I and II
MAG.T21.45_02141	760192.Halhy_2614	1.7e-156	559.3	Sphingobacteriia	putP			ko:K03307,ko:K14387	ko04725,ko05231,map04725,map05231				ko00000,ko00001,ko02000	2.A.21,2.A.21.8			Bacteria	1IZ8B@117747,4NH7H@976,COG0591@1,COG0591@2	NA|NA|NA	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MAG.T21.45_02142	1408473.JHXO01000011_gene3058	3.4e-122	444.9	Bacteroidia	hddA		2.7.1.168	ko:K07031	ko00540,map00540		R09770	RC00002,RC00078	ko00000,ko00001,ko01000				Bacteria	2G38R@200643,4NHEN@976,COG2605@1,COG2605@2	NA|NA|NA	S	GHMP kinase, N-terminal domain protein
MAG.T21.45_02143	1122179.KB890491_gene4424	2.5e-102	379.0	Sphingobacteriia													Bacteria	1IPPF@117747,4NEZI@976,COG0438@1,COG0438@2	NA|NA|NA	M	PFAM Glycosyl transferase, group 1
MAG.T21.45_02144	700598.Niako_2548	7.3e-53	213.8	Sphingobacteriia	gmhA		5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1IRJQ@117747,4NJX7@976,COG0279@1,COG0279@2	NA|NA|NA	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate
MAG.T21.45_02145	760192.Halhy_2136	3e-246	857.8	Sphingobacteriia	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391		ko:K03703	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	1IPMR@117747,4NE61@976,COG0322@1,COG0322@2	NA|NA|NA	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MAG.T21.45_02146	760192.Halhy_2684	6.6e-81	307.4	Sphingobacteriia													Bacteria	1IRUS@117747,4NICN@976,COG1028@1,COG1028@2	NA|NA|NA	IQ	PFAM Short-chain dehydrogenase reductase SDR
MAG.T21.45_02147	926562.Oweho_2422	1.5e-82	312.8	Cryomorphaceae	lpxH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005			iE2348C_1286.E2348C_0457	Bacteria	1HWZZ@117743,2PADT@246874,4NEF1@976,COG2908@1,COG2908@2	NA|NA|NA	S	Calcineurin-like phosphoesterase
MAG.T21.45_02148	760192.Halhy_2686	3.4e-21	109.0	Sphingobacteriia													Bacteria	1IUF2@117747,2CGN1@1,3348T@2,4NX4E@976	NA|NA|NA		
MAG.T21.45_02149	760192.Halhy_4547	4.1e-126	458.4	Sphingobacteriia													Bacteria	1IQCY@117747,4NF9W@976,COG0671@1,COG0671@2	NA|NA|NA	I	Phosphoesterase PA-phosphatase related
MAG.T21.45_02150	760192.Halhy_3323	1.6e-130	472.6	Sphingobacteriia	pdxA		1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000				Bacteria	1IP2F@117747,4NEUR@976,COG1995@1,COG1995@2	NA|NA|NA	H	Belongs to the PdxA family
MAG.T21.45_02151	760192.Halhy_3324	4e-49	201.4	Sphingobacteriia	lspA		3.4.23.36	ko:K03101	ko03060,map03060				ko00000,ko00001,ko01000,ko01002				Bacteria	1IQPW@117747,4NEZN@976,COG0597@1,COG0597@2	NA|NA|NA	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MAG.T21.45_02152	760192.Halhy_1993	3.4e-28	131.0	Bacteria				ko:K03892					ko00000,ko03000				Bacteria	COG0640@1,COG0640@2	NA|NA|NA	K	DNA-binding transcription factor activity
MAG.T21.45_02154	760192.Halhy_1992	1.5e-42	178.7	Sphingobacteriia	bigR			ko:K03892,ko:K07721,ko:K22042,ko:K22491					ko00000,ko03000				Bacteria	1IYKV@117747,4P4RQ@976,COG0640@1,COG0640@2	NA|NA|NA	K	helix_turn_helix, Arsenical Resistance Operon Repressor
MAG.T21.45_02155	1122176.KB903541_gene216	3.2e-20	104.8	Sphingobacteriia	bigR			ko:K03892,ko:K07721,ko:K22042,ko:K22491					ko00000,ko03000				Bacteria	1IYKV@117747,4P4RQ@976,COG0640@1,COG0640@2	NA|NA|NA	K	helix_turn_helix, Arsenical Resistance Operon Repressor
MAG.T21.45_02156	760192.Halhy_1991	1.9e-36	159.5	Sphingobacteriia	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564		ko:K14742					ko00000,ko03016				Bacteria	1IXRG@117747,4NDUR@976,COG1214@1,COG1214@2	NA|NA|NA	O	Glycoprotease family
MAG.T21.45_02157	1122179.KB890435_gene927	7.6e-133	480.3	Sphingobacteriia	prfA	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02835					ko00000,ko03012				Bacteria	1IPKJ@117747,4NF72@976,COG0216@1,COG0216@2	NA|NA|NA	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MAG.T21.45_02158	760192.Halhy_1994	6.7e-34	152.1	Bacteroidetes													Bacteria	2E821@1,332G3@2,4NVE5@976	NA|NA|NA		
MAG.T21.45_02159	760192.Halhy_3061	1.7e-33	150.6	Bacteroidetes													Bacteria	4NG4A@976,COG2067@1,COG2067@2	NA|NA|NA	I	long-chain fatty acid transport protein
MAG.T21.45_02160	118173.KB235914_gene450	6.1e-93	347.8	Oscillatoriales													Bacteria	1G2M9@1117,1H9MM@1150,COG2425@1,COG2425@2	NA|NA|NA	S	VWA domain containing CoxE-like protein
MAG.T21.45_02161	760192.Halhy_3054	3.5e-80	305.4	Sphingobacteriia	mprF			ko:K07027					ko00000,ko02000	4.D.2			Bacteria	1IYUH@117747,4NIWG@976,COG0392@1,COG0392@2	NA|NA|NA	S	Lysylphosphatidylglycerol synthase TM region
MAG.T21.45_02162	760192.Halhy_3644	0.0	1159.4	Sphingobacteriia				ko:K03641,ko:K11016	ko03070,map03070				ko00000,ko00001,ko02000,ko02042,ko02044	2.C.1.2			Bacteria	1IV8M@117747,4PNV1@976,COG0823@1,COG0823@2,COG2831@1,COG2831@2	NA|NA|NA	U	hemolysin activation secretion protein
MAG.T21.45_02163	760192.Halhy_3645	8.6e-71	273.5	Sphingobacteriia	ycbL	GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615	3.1.2.6	ko:K01069	ko00620,map00620		R01736	RC00004,RC00137	ko00000,ko00001,ko01000				Bacteria	1J079@117747,4NE2Y@976,COG0491@1,COG0491@2	NA|NA|NA	P	beta-lactamase domain protein
MAG.T21.45_02164	1122176.KB903540_gene130	5.3e-18	98.2	Sphingobacteriia													Bacteria	1J0RR@117747,4PMCF@976,COG3595@1,COG3595@2	NA|NA|NA	S	Putative auto-transporter adhesin, head GIN domain
MAG.T21.45_02165	760192.Halhy_3454	6.6e-234	816.6	Sphingobacteriia	glyQS	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029			iSB619.SA_RS07880	Bacteria	1IPE0@117747,4NE1C@976,COG0423@1,COG0423@2	NA|NA|NA	J	Catalyzes the attachment of glycine to tRNA(Gly)
MAG.T21.45_02166	760192.Halhy_2739	2.9e-152	545.0	Sphingobacteriia	ald		1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100		R00396	RC00008	ko00000,ko00001,ko01000				Bacteria	1INRN@117747,4NE8F@976,COG0686@1,COG0686@2	NA|NA|NA	E	alanine dehydrogenase
MAG.T21.45_02167	760192.Halhy_3967	4.5e-48	198.0	Sphingobacteriia	nudL	GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818											Bacteria	1IT9X@117747,4NM6C@976,COG0494@1,COG0494@2	NA|NA|NA	L	NUDIX domain
MAG.T21.45_02168	760192.Halhy_3583	8.8e-97	360.1	Sphingobacteriia	hemD		2.1.1.107,2.5.1.61,4.2.1.75	ko:K01719,ko:K01749,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084,R03165,R03194	RC00003,RC00871,RC01861,RC02317	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPP4@117747,4NEQ3@976,COG1587@1,COG1587@2	NA|NA|NA	H	Uroporphyrinogen-III synthase
MAG.T21.45_02169	1122179.KB890414_gene1841	6.1e-16	91.7	Bacteroidetes													Bacteria	2CEK0@1,321UV@2,4NUC9@976	NA|NA|NA	S	Psort location CytoplasmicMembrane, score
MAG.T21.45_02170	760192.Halhy_3192	4.3e-114	418.3	Sphingobacteriia													Bacteria	1IXEP@117747,4NEFW@976,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
MAG.T21.45_02171	760192.Halhy_3191	4.3e-60	238.0	Sphingobacteriia													Bacteria	1IXKQ@117747,4NM5Q@976,COG0745@1,COG0745@2	NA|NA|NA	K	Two component transcriptional regulator, winged helix family
MAG.T21.45_02172	760192.Halhy_3384	1.7e-189	669.5	Sphingobacteriia	ppiD		5.2.1.8	ko:K01802,ko:K03769,ko:K03770					ko00000,ko01000,ko03110				Bacteria	1INT0@117747,4NDZZ@976,COG0760@1,COG0760@2	NA|NA|NA	O	peptidylprolyl isomerase
MAG.T21.45_02174	760192.Halhy_3335	2e-237	828.6	Sphingobacteriia	fadD		6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1			Bacteria	1IQD6@117747,4NEA4@976,COG1022@1,COG1022@2	NA|NA|NA	I	AMP-dependent synthetase
MAG.T21.45_02175	760192.Halhy_2911	2.2e-93	349.0	Sphingobacteriia	ycgE			ko:K21089,ko:K21972,ko:K22491	ko02026,map02026				ko00000,ko00001,ko03000				Bacteria	1IS5U@117747,4NERC@976,COG0789@1,COG0789@2,COG5012@1,COG5012@2	NA|NA|NA	K	MerR family
MAG.T21.45_02176	760192.Halhy_2912	4.9e-203	714.9	Bacteroidetes			3.2.1.4,5.2.1.8	ko:K01179,ko:K03768,ko:K08738	ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko03110	3.D.4.6	GH5,GH9		Bacteria	4NJU9@976,COG1361@1,COG1361@2,COG3291@1,COG3291@2	NA|NA|NA	MU	calcium- and calmodulin-responsive adenylate cyclase activity
MAG.T21.45_02177	760192.Halhy_3188	7.8e-160	570.1	Sphingobacteriia	bshA	GO:0003674,GO:0003824,GO:0016740,GO:0016757		ko:K00754					ko00000,ko01000		GT4		Bacteria	1IPP6@117747,4NFPA@976,COG0438@1,COG0438@2	NA|NA|NA	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase
MAG.T21.45_02178	760192.Halhy_3373	2.7e-223	781.9	Sphingobacteriia													Bacteria	1IVTD@117747,4NDWE@976,COG3292@1,COG3292@2	NA|NA|NA	T	Two component regulator propeller domain protein
MAG.T21.45_02179	1122176.KB903550_gene4342	3.8e-62	244.6	Sphingobacteriia	nadD		2.7.7.18,3.6.1.55	ko:K00969,ko:K03574	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400				Bacteria	1IRZ1@117747,4NFQI@976,COG1057@1,COG1057@2	NA|NA|NA	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MAG.T21.45_02181	760192.Halhy_3376	2.4e-137	495.4	Sphingobacteriia	dnaN		2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1IP8C@117747,4NESB@976,COG0592@1,COG0592@2	NA|NA|NA	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MAG.T21.45_02182	760192.Halhy_3558	3.6e-81	308.9	Sphingobacteriia				ko:K07263					ko00000,ko01000,ko01002				Bacteria	1IQAH@117747,4NEPT@976,COG0612@1,COG0612@2	NA|NA|NA	S	Peptidase M16
MAG.T21.45_02183	760192.Halhy_3557	3.1e-163	581.3	Sphingobacteriia	mreB			ko:K03569					ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1			Bacteria	1IPMZ@117747,4NETQ@976,COG1077@1,COG1077@2	NA|NA|NA	D	Cell shape determining protein MreB Mrl
MAG.T21.45_02184	1168289.AJKI01000011_gene652	3.7e-42	178.7	Marinilabiliaceae	mreC			ko:K03570					ko00000,ko03036	9.B.157.1			Bacteria	2FMWS@200643,3XIT1@558415,4NF14@976,COG1792@1,COG1792@2	NA|NA|NA	M	rod shape-determining protein MreC
MAG.T21.45_02185	1122176.KB903550_gene4336	1.2e-25	123.2	Sphingobacteriia	mreD												Bacteria	1ISUS@117747,2AFDM@1,315DF@2,4NQ5K@976	NA|NA|NA	S	rod shape-determining protein MreD
MAG.T21.45_02186	760192.Halhy_3554	4.5e-197	694.5	Sphingobacteriia	mrdA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501				ko00000,ko00001,ko01000,ko01011			iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604	Bacteria	1IQ2C@117747,4NE47@976,COG0768@1,COG0768@2	NA|NA|NA	M	Penicillin-binding protein 2
MAG.T21.45_02187	760192.Halhy_3553	6e-107	394.4	Bacteroidetes	capA			ko:K07282					ko00000				Bacteria	4NI5N@976,COG2843@1,COG2843@2	NA|NA|NA	M	Bacterial capsule synthesis protein
MAG.T21.45_02188	760192.Halhy_3552	2.4e-41	175.3	Sphingobacteriia	folA		1.1.1.262,1.5.1.3	ko:K00097,ko:K00287,ko:K18589	ko00670,ko00750,ko00790,ko01100,ko01523,map00670,map00750,map00790,map01100,map01523	M00124,M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R05681,R05837,R07406,R11765	RC00089,RC00109,RC00110,RC00158,RC00675,RC01475	br01600,ko00000,ko00001,ko00002,ko01000,ko01504				Bacteria	1ISG3@117747,4NQ2Y@976,COG0262@1,COG0262@2	NA|NA|NA	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MAG.T21.45_02189	929562.Emtol_3076	1.1e-138	500.0	Cytophagia													Bacteria	47MJG@768503,4NFWX@976,COG3000@1,COG3000@2	NA|NA|NA	I	Fatty acid hydroxylase superfamily
MAG.T21.45_02190	760192.Halhy_5074	6e-56	224.2	Sphingobacteriia													Bacteria	1IS95@117747,4NG89@976,COG0702@1,COG0702@2	NA|NA|NA	GM	epimerase
MAG.T21.45_02191	760192.Halhy_3551	1.2e-100	373.6	Sphingobacteriia													Bacteria	1INN1@117747,28HQ3@1,2Z7XW@2,4NF9H@976	NA|NA|NA	S	Protein of unknown function (DUF2851)
MAG.T21.45_02192	760192.Halhy_3479	3.9e-67	261.5	Sphingobacteriia	hddC		2.7.7.13,2.7.7.24	ko:K00966,ko:K00973	ko00051,ko00520,ko00521,ko00523,ko00525,ko01100,ko01110,ko01130,map00051,map00520,map00521,map00523,map00525,map01100,map01110,map01130	M00114,M00361,M00362,M00793	R00885,R02328	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	1IXAV@117747,4NMJ5@976,COG1208@1,COG1208@2	NA|NA|NA	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)
MAG.T21.45_02193	760192.Halhy_2005	2.3e-97	362.5	Sphingobacteriia	lpxK	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005			iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396	Bacteria	1IQ8A@117747,4NE2I@976,COG1663@1,COG1663@2	NA|NA|NA	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
MAG.T21.45_02194	760192.Halhy_4010	0.0	1241.5	Sphingobacteriia				ko:K08676					ko00000,ko01000,ko01002				Bacteria	1IR3P@117747,4NGU2@976,COG0793@1,COG0793@2,COG4946@1,COG4946@2	NA|NA|NA	M	Tricorn protease homolog
MAG.T21.45_02195	1380600.AUYN01000009_gene1957	1.9e-253	882.1	Flavobacteriia													Bacteria	1I057@117743,4NG60@976,COG1554@1,COG1554@2	NA|NA|NA	G	hydrolase, family 65, central catalytic
MAG.T21.45_02196	1122176.KB903548_gene1141	2.1e-47	196.8	Bacteroidetes	plsB		2.3.1.15	ko:K00630,ko:K00631,ko:K14598	ko00561,ko00564,ko00906,ko01100,ko01110,map00561,map00564,map00906,map01100,map01110	M00089	R00851,R07545,R07547,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	4NK8Z@976,COG0204@1,COG0204@2	NA|NA|NA	I	Phosphate acyltransferases
MAG.T21.45_02197	929556.Solca_2271	9.1e-65	254.2	Sphingobacteriia				ko:K20541					ko00000,ko02000	4.D.3.1.6			Bacteria	1IQGQ@117747,4NESG@976,COG1215@1,COG1215@2	NA|NA|NA	M	PFAM Glycosyl transferase family 2
MAG.T21.45_02198	1086011.HJ01_02282	2.3e-134	485.7	Flavobacterium													Bacteria	1HYWP@117743,2NUIZ@237,4NHSX@976,COG0348@1,COG0348@2	NA|NA|NA	C	4Fe-4S dicluster domain
MAG.T21.45_02199	1122176.KB903550_gene4348	4.9e-102	378.3	Sphingobacteriia	norW	GO:0000166,GO:0000302,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010035,GO:0015044,GO:0016491,GO:0016730,GO:0016731,GO:0017144,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042493,GO:0042737,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0044270,GO:0044424,GO:0044464,GO:0046209,GO:0046210,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071241,GO:0071731,GO:0071732,GO:0072593,GO:0097159,GO:0097366,GO:1901265,GO:1901363,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:2001057	1.18.1.1,1.7.1.15	ko:K00362,ko:K05297,ko:K12265	ko00071,ko00910,ko01120,ko05132,map00071,map00910,map01120,map05132	M00530	R00787,R02000	RC00176	ko00000,ko00001,ko00002,ko01000			iEcHS_1320.EcHS_A2847,iSSON_1240.SSON_2855	Bacteria	1IUVE@117747,4NET1@976,COG0446@1,COG0446@2	NA|NA|NA	S	Pyridine nucleotide-disulphide oxidoreductase
MAG.T21.45_02201	1121904.ARBP01000017_gene5093	6.7e-110	404.8	Cytophagia													Bacteria	47V4E@768503,4NFAP@976,COG1409@1,COG1409@2	NA|NA|NA	S	Calcineurin-like phosphoesterase
MAG.T21.45_02202	760192.Halhy_2907	3.6e-62	245.0	Sphingobacteriia	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030		R01066	RC00436,RC00437	ko00000,ko00001,ko01000				Bacteria	1IXCK@117747,4NGE3@976,COG0274@1,COG0274@2	NA|NA|NA	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MAG.T21.45_02203	929562.Emtol_3357	2.1e-61	241.9	Cytophagia			1.3.99.16	ko:K07302,ko:K07303					ko00000,ko01000				Bacteria	47Q3P@768503,4NMVV@976,COG2080@1,COG2080@2	NA|NA|NA	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs
MAG.T21.45_02204	929562.Emtol_3356	0.0	1125.5	Cytophagia			1.3.99.16	ko:K07303					ko00000,ko01000				Bacteria	47N2K@768503,4NFFU@976,COG1529@1,COG1529@2	NA|NA|NA	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
MAG.T21.45_02206	1120965.AUBV01000012_gene1401	8.5e-146	523.1	Cytophagia	yghX		3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130		R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000				Bacteria	47JGG@768503,4NEUX@976,COG0412@1,COG0412@2	NA|NA|NA	Q	dienelactone hydrolase
MAG.T21.45_02207	880070.Cycma_0935	1.2e-170	606.3	Bacteroidetes													Bacteria	4NEN5@976,COG0673@1,COG0673@2	NA|NA|NA	S	Pfam Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_02209	760192.Halhy_3611	0.0	1597.0	Sphingobacteriia	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_0661	Bacteria	1INWJ@117747,4NEQ0@976,COG0458@1,COG0458@2	NA|NA|NA	EF	Carbamoyl-phosphate synthase
MAG.T21.45_02210	1122176.KB903540_gene21	1.7e-18	99.4	Sphingobacteriia	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575											Bacteria	1IU3P@117747,2ADSH@1,313I2@2,4NQMU@976	NA|NA|NA	S	GldH lipoprotein
MAG.T21.45_02211	760192.Halhy_3807	2.7e-136	491.9	Sphingobacteriia	dnaJ	GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141		ko:K03686					ko00000,ko03029,ko03110				Bacteria	1IQ7V@117747,4NF41@976,COG0484@1,COG0484@2	NA|NA|NA	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MAG.T21.45_02212	1122176.KB903540_gene23	9.6e-47	193.4	Sphingobacteriia	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363		ko:K02652,ko:K03687					ko00000,ko02035,ko02044,ko03029,ko03110	3.A.15.2			Bacteria	1ISPN@117747,4NQ6M@976,COG0576@1,COG0576@2	NA|NA|NA	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MAG.T21.45_02213	760192.Halhy_3809	4.1e-42	177.9	Bacteroidetes													Bacteria	4NUFI@976,COG0526@1,COG0526@2	NA|NA|NA	CO	Thioredoxin-like
MAG.T21.45_02214	1122179.KB890448_gene2992	3.4e-111	408.3	Sphingobacteriia			2.3.1.157,2.7.7.13,2.7.7.23,2.7.7.24,5.4.2.8	ko:K00973,ko:K04042,ko:K16881	ko00051,ko00520,ko00521,ko00523,ko00525,ko01100,ko01110,ko01130,map00051,map00520,map00521,map00523,map00525,map01100,map01110,map01130	M00114,M00362,M00793	R00416,R00885,R01818,R02328,R05332	RC00002,RC00004,RC00166,RC00408	ko00000,ko00001,ko00002,ko01000				Bacteria	1IVAZ@117747,4NIRW@976,COG1208@1,COG1208@2	NA|NA|NA	JM	Nucleotidyl transferase
MAG.T21.45_02215	760192.Halhy_3260	5.1e-106	391.0	Sphingobacteriia	atpG	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138	Bacteria	1IQEQ@117747,4NECM@976,COG0224@1,COG0224@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MAG.T21.45_02216	760192.Halhy_3259	5.7e-257	893.3	Sphingobacteriia	atpA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1		iSB619.SA_RS10975	Bacteria	1IP4E@117747,4NFZW@976,COG0056@1,COG0056@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MAG.T21.45_02217	760192.Halhy_3258	2.3e-35	155.6	Sphingobacteriia	atpH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		iSF_1195.SF3815,iSFxv_1172.SFxv_4157,iS_1188.S3953	Bacteria	1ITDM@117747,4NSNF@976,COG0712@1,COG0712@2	NA|NA|NA	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MAG.T21.45_02218	984262.SGRA_2337	4.6e-26	124.8	Bacteria	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		e_coli_core.b3736,iAF1260.b3736,iB21_1397.B21_03564,iBWG_1329.BWG_3427,iE2348C_1286.E2348C_4046,iEC042_1314.EC042_4123,iEC55989_1330.EC55989_4211,iECABU_c1320.ECABU_c42210,iECBD_1354.ECBD_4296,iECB_1328.ECB_03620,iECDH10B_1368.ECDH10B_3923,iECDH1ME8569_1439.ECDH1ME8569_3624,iECD_1391.ECD_03620,iECED1_1282.ECED1_4426,iECH74115_1262.ECH74115_5172,iECIAI1_1343.ECIAI1_3920,iECIAI39_1322.ECIAI39_4340,iECO103_1326.ECO103_4422,iECO111_1330.ECO111_4570,iECO26_1355.ECO26_4842,iECOK1_1307.ECOK1_4185,iECP_1309.ECP_3935,iECS88_1305.ECS88_4158,iECSE_1348.ECSE_4026,iECSF_1327.ECSF_3584,iECSP_1301.ECSP_4786,iECUMN_1333.ECUMN_4266,iECW_1372.ECW_m4039,iECs_1301.ECs4678,iEKO11_1354.EKO11_4609,iETEC_1333.ETEC_4027,iEcDH1_1363.EcDH1_4231,iEcE24377_1341.EcE24377A_4252,iEcHS_1320.EcHS_A3952,iEcSMS35_1347.EcSMS35_4104,iEcolC_1368.EcolC_4258,iG2583_1286.G2583_4532,iJO1366.b3736,iJR904.b3736,iSDY_1059.SDY_4012,iSFV_1184.SFV_3762,iSF_1195.SF3816,iSFxv_1172.SFxv_4159,iSSON_1240.SSON_3883,iS_1188.S3952,iSbBS512_1146.SbBS512_E4185,iUMN146_1321.UM146_18870,iUMNK88_1353.UMNK88_4548,iUTI89_1310.UTI89_C4291,iWFL_1372.ECW_m4039,iY75_1357.Y75_RS18390,iZ_1308.Z5234,ic_1306.c4664	Bacteria	COG0711@1,COG0711@2	NA|NA|NA	C	ATP synthesis coupled proton transport
MAG.T21.45_02219	762903.Pedsa_2510	8.9e-14	82.4	Bacteroidetes	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		iHN637.CLJU_RS01165	Bacteria	4NURW@976,COG0636@1,COG0636@2	NA|NA|NA	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MAG.T21.45_02220	760192.Halhy_3255	9.4e-101	374.0	Sphingobacteriia	atpB			ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1			Bacteria	1IPTF@117747,4NEPK@976,COG0356@1,COG0356@2	NA|NA|NA	C	it plays a direct role in the translocation of protons across the membrane
MAG.T21.45_02221	760192.Halhy_3513	5.9e-238	830.1	Sphingobacteriia	nadB	GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.3.5.4,1.4.3.16	ko:K00244,ko:K00278	ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00115,M00150,M00173	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000			iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJN678.nadB,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iSbBS512_1146.nadB,iY75_1357.Y75_RS13445,iYL1228.KPN_02899	Bacteria	1IQPX@117747,4NGUE@976,COG0029@1,COG0029@2	NA|NA|NA	H	Catalyzes the oxidation of L-aspartate to iminoaspartate
MAG.T21.45_02222	1122176.KB903550_gene4276	1.2e-95	356.3	Sphingobacteriia													Bacteria	1J0X6@117747,4PNB1@976,COG1216@1,COG1216@2	NA|NA|NA	S	Glycosyl transferase family 2
MAG.T21.45_02223	1313421.JHBV01000029_gene1946	4.1e-35	154.5	Sphingobacteriia													Bacteria	1ISSQ@117747,2DEYG@1,2ZPSM@2,4NNJW@976	NA|NA|NA		
MAG.T21.45_02224	760192.Halhy_3056	1.5e-262	912.1	Sphingobacteriia	bfmBA		1.2.4.1,1.2.4.4	ko:K00161,ko:K00167,ko:K11381,ko:K21416,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1IP3Q@117747,4NE71@976,COG0022@1,COG0022@2,COG1071@1,COG1071@2	NA|NA|NA	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type
MAG.T21.45_02225	1392489.JPOL01000002_gene2064	5.2e-24	118.6	Leeuwenhoekiella													Bacteria	1HWN0@117743,2XIUU@283735,4NH36@976,COG2885@1,COG2885@2	NA|NA|NA	M	Type IX secretion system membrane protein PorP/SprF
MAG.T21.45_02226	1131812.JQMS01000001_gene1787	7.6e-89	334.0	Flavobacteriia													Bacteria	1I15E@117743,4NN89@976,COG4823@1,COG4823@2	NA|NA|NA	V	Abi-like protein
MAG.T21.45_02227	869213.JCM21142_72539	7.9e-45	188.7	Bacteria			3.2.1.78	ko:K01218,ko:K12287,ko:K12548	ko00051,ko02024,map00051,map02024		R01332	RC00467	ko00000,ko00001,ko01000,ko02044		GH26		Bacteria	COG2911@1,COG2911@2,COG3210@1,COG3210@2,COG3386@1,COG3386@2	NA|NA|NA	S	protein secretion
MAG.T21.45_02228	1237149.C900_00138	1.1e-37	162.9	Cytophagia													Bacteria	29AZZ@1,2ZXYX@2,47Q19@768503,4NP6M@976	NA|NA|NA		
MAG.T21.45_02229	760192.Halhy_3205	1.9e-280	971.5	Sphingobacteriia	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363		ko:K03495			R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036				Bacteria	1INTV@117747,4NFNH@976,COG0445@1,COG0445@2	NA|NA|NA	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MAG.T21.45_02230	1122176.KB903550_gene4306	7.3e-71	273.5	Sphingobacteriia													Bacteria	1IXGV@117747,4PKKF@976,COG0526@1,COG0526@2	NA|NA|NA	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MAG.T21.45_02231	760192.Halhy_3509	4.2e-201	707.6	Sphingobacteriia	gpmI	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000			iECSE_1348.ECSE_3895,iJN678.yibO,iJN746.PP_5056	Bacteria	1INQA@117747,4NEQT@976,COG0696@1,COG0696@2	NA|NA|NA	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MAG.T21.45_02232	760192.Halhy_3507	4e-20	104.4	Sphingobacteriia													Bacteria	1IUPS@117747,2E4AG@1,32Z66@2,4NUXA@976	NA|NA|NA	S	Domain of unknown function (DUF4783)
MAG.T21.45_02233	1492737.FEM08_35140	5.9e-95	354.0	Flavobacterium	nth		4.2.99.18	ko:K10773	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1HWQK@117743,2NT1F@237,4NE7K@976,COG0177@1,COG0177@2	NA|NA|NA	L	Protein of unknown function (DUF2400)
MAG.T21.45_02236	760192.Halhy_0886	0.0	1287.3	Sphingobacteriia				ko:K08676					ko00000,ko01000,ko01002				Bacteria	1IWHI@117747,4NGU2@976,COG0793@1,COG0793@2,COG4946@1,COG4946@2	NA|NA|NA	M	Tricorn protease PDZ domain
MAG.T21.45_02237	760192.Halhy_6041	6e-34	150.6	Sphingobacteriia	recX	GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496	2.4.1.337	ko:K03565,ko:K19002	ko00561,ko01100,map00561,map01100		R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03400		GT4		Bacteria	1IT8A@117747,4NSAS@976,COG2137@1,COG2137@2	NA|NA|NA	S	Modulates RecA activity
MAG.T21.45_02239	760192.Halhy_4443	3.5e-171	608.2	Bacteroidetes													Bacteria	4NIJ4@976,COG1672@1,COG1672@2	NA|NA|NA	S	Psort location Cytoplasmic, score 8.96
MAG.T21.45_02240	471854.Dfer_1016	6.3e-58	230.7	Cytophagia			4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000				Bacteria	47MP6@768503,4NHVV@976,COG0800@1,COG0800@2	NA|NA|NA	G	KDPG and KHG aldolase
MAG.T21.45_02241	926549.KI421517_gene3140	1.1e-61	243.8	Cytophagia	dgoK		2.7.1.58	ko:K00883	ko00052,ko01100,map00052,map01100	M00552	R03387	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	47NSE@768503,4NIGZ@976,COG3734@1,COG3734@2	NA|NA|NA	G	2-keto-3-deoxy-galactonokinase
MAG.T21.45_02242	761193.Runsl_1881	2.9e-31	141.7	Bacteroidetes													Bacteria	291SY@1,2ZPCW@2,4P6UE@976	NA|NA|NA		
MAG.T21.45_02244	335543.Sfum_2310	6.6e-99	367.5	Syntrophobacterales	qmcA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944											Bacteria	1MUM8@1224,2MQ9P@213462,2WISZ@28221,42NX0@68525,COG0330@1,COG0330@2	NA|NA|NA	O	PFAM Band 7 protein
MAG.T21.45_02245	335543.Sfum_2309	3.4e-23	114.8	Bacteria	nfeD			ko:K07340					ko00000				Bacteria	COG1585@1,COG1585@2	NA|NA|NA	OU	cellular response to DNA damage stimulus
MAG.T21.45_02246	888743.HMPREF9141_2297	1.8e-27	129.4	Bacteria			3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	COG0210@1,COG0210@2	NA|NA|NA	L	ATP-dependent DNA helicase activity
MAG.T21.45_02247	869213.JCM21142_104490	4e-62	244.6	Cytophagia													Bacteria	28KWY@1,2ZAD1@2,47SKN@768503,4NM1H@976	NA|NA|NA		
MAG.T21.45_02248	1189620.AJXL01000062_gene254	4.1e-15	87.8	Flavobacterium													Bacteria	1INF1@117743,2AQE1@1,2NZDV@237,31FKF@2,4PIZJ@976	NA|NA|NA		
MAG.T21.45_02249	485918.Cpin_1948	1.2e-143	516.5	Sphingobacteriia				ko:K06926					ko00000				Bacteria	1IRPC@117747,4NE5J@976,COG1106@1,COG1106@2	NA|NA|NA	S	AAA domain, putative AbiEii toxin, Type IV TA system
MAG.T21.45_02250	485918.Cpin_1949	7e-33	146.7	Sphingobacteriia													Bacteria	1ITSW@117747,2EX0P@1,33QBW@2,4NTCE@976	NA|NA|NA	S	RloB-like protein
MAG.T21.45_02252	869213.JCM21142_52300	9.3e-56	223.4	Cytophagia			2.7.7.7,3.6.4.12	ko:K02337,ko:K02342,ko:K03654	ko00230,ko00240,ko01100,ko03018,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03018,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	47RG4@768503,4NP7B@976,COG0847@1,COG0847@2	NA|NA|NA	L	Exonuclease
MAG.T21.45_02253	493475.GARC_1198	5.2e-11	74.3	Proteobacteria													Bacteria	1NHMM@1224,COG3428@1,COG3428@2	NA|NA|NA	S	Bacterial PH domain
MAG.T21.45_02259	1304284.L21TH_2026	4e-63	248.8	Clostridia	sbcD			ko:K03547					ko00000,ko03400				Bacteria	1V3MP@1239,24J4M@186801,COG0420@1,COG0420@2	NA|NA|NA	L	Calcineurin-like phosphoesterase superfamily domain
MAG.T21.45_02260	1031288.AXAA01000010_gene469	1.8e-49	204.5	Clostridia	CP_0646			ko:K03546					ko00000,ko03400				Bacteria	1UQNY@1239,24UHC@186801,COG0419@1,COG0419@2,COG1196@1,COG1196@2	NA|NA|NA	L	AAA domain
MAG.T21.45_02262	1433126.BN938_1848	4.8e-162	577.8	Bacteroidia													Bacteria	2FQ8Q@200643,4NGM8@976,COG0323@1,COG0323@2	NA|NA|NA	L	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MAG.T21.45_02263	760192.Halhy_2570	3.8e-277	961.1	Sphingobacteriia													Bacteria	1IUF7@117747,4NHD1@976,COG1100@1,COG1100@2	NA|NA|NA	L	Z1 domain
MAG.T21.45_02264	203275.BFO_0626	6.8e-75	287.7	Porphyromonadaceae													Bacteria	22Z4J@171551,2FPYV@200643,2Z9WJ@2,4NM2Z@976,arCOG12551@1	NA|NA|NA	S	Putative  PD-(D/E)XK family member, (DUF4420)
MAG.T21.45_02265	1515615.HQ41_03185	1.3e-278	965.7	Porphyromonadaceae													Bacteria	22ZSK@171551,2FR8U@200643,2Z7VT@2,4NFYT@976,arCOG06613@1	NA|NA|NA	S	AIPR protein
MAG.T21.45_02266	56110.Oscil6304_2387	7.6e-14	82.8	Cyanobacteria													Bacteria	1GGNK@1117,2EIT4@1,33CIF@2	NA|NA|NA	S	Protein of unknown function (DUF2442)
MAG.T21.45_02267	1034807.FBFL15_2509	2.1e-55	222.2	Bacteroidetes													Bacteria	2E7TR@1,3328U@2,4P2HC@976	NA|NA|NA		
MAG.T21.45_02268	1123277.KB893172_gene850	1.3e-128	466.8	Cytophagia													Bacteria	47MKM@768503,4NH8G@976,COG4935@1,COG4935@2	NA|NA|NA	O	PFAM Spore coat protein CotH
MAG.T21.45_02269	388413.ALPR1_17963	1.2e-139	503.1	Cytophagia			3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142		R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042		GH33		Bacteria	47JRH@768503,4NFNK@976,COG4409@1,COG4409@2	NA|NA|NA	G	BNR repeat-like domain
MAG.T21.45_02270	1267211.KI669560_gene610	6.6e-74	284.3	Bacteria													Bacteria	COG1082@1,COG1082@2	NA|NA|NA	G	myo-inosose-2 dehydratase activity
MAG.T21.45_02271	1233951.IO90_16000	3e-28	130.6	Flavobacteriia													Bacteria	1I2P5@117743,4NNKA@976,COG4185@1,COG4185@2	NA|NA|NA	S	Zeta toxin
MAG.T21.45_02272	755732.Fluta_2657	5.3e-09	66.2	Flavobacteriia													Bacteria	1I6J8@117743,2EGVN@1,33AMV@2,4NYC6@976	NA|NA|NA		
MAG.T21.45_02273	1122179.KB890433_gene4075	1e-157	563.9	Sphingobacteriia	chiA	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.2.1.14,3.2.1.17	ko:K03933,ko:K13381	ko00520,ko01100,map00520,map01100		R01206,R02334	RC00467	ko00000,ko00001,ko01000		AA10,CBM15,CBM73,GH18		Bacteria	1IX1I@117747,4PPP7@976,COG3979@1,COG3979@2,COG4935@1,COG4935@2	NA|NA|NA	O	chitinase
MAG.T21.45_02274	1122176.KB903543_gene544	6.4e-204	718.4	Sphingobacteriia													Bacteria	1J0JM@117747,4P0IA@976,COG0745@1,COG0745@2,COG3292@1,COG3292@2,COG5002@1,COG5002@2	NA|NA|NA	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MAG.T21.45_02275	1122176.KB903543_gene541	4e-122	444.9	Sphingobacteriia													Bacteria	1J0W0@117747,4NDYS@976,COG4225@1,COG4225@2	NA|NA|NA	S	Glycosyl Hydrolase Family 88
MAG.T21.45_02276	1122176.KB903543_gene542	4.5e-132	478.4	Sphingobacteriia													Bacteria	1IZYF@117747,2EBBZ@1,335CQ@2,4NXF2@976	NA|NA|NA		
MAG.T21.45_02277	1122176.KB903543_gene543	1.9e-295	1021.9	Sphingobacteriia													Bacteria	1IWAD@117747,4PN3N@976,COG1629@1,COG1629@2	NA|NA|NA	P	TonB dependent receptor
MAG.T21.45_02278	756272.Plabr_3173	7.1e-134	484.2	Planctomycetes													Bacteria	2IXHT@203682,COG3119@1,COG3119@2	NA|NA|NA	P	COG3119 Arylsulfatase A
MAG.T21.45_02279	929556.Solca_0767	1.6e-25	122.9	Sphingobacteriia													Bacteria	1IUDR@117747,4NUTN@976,COG2318@1,COG2318@2	NA|NA|NA	S	DinB superfamily
MAG.T21.45_02280	999419.HMPREF1077_00464	1.9e-205	721.8	Bacteroidia													Bacteria	2G2S5@200643,4NH96@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_02281	449673.BACSTE_01641	9.9e-199	699.5	Bacteroidaceae				ko:K06921					ko00000				Bacteria	2FPC6@200643,4AMU7@815,4NJ2E@976,COG1672@1,COG1672@2	NA|NA|NA	S	ATPase (AAA superfamily)
MAG.T21.45_02282	929703.KE386491_gene416	1.9e-142	512.3	Cytophagia			3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110		GH20		Bacteria	47TJT@768503,4NGV2@976,COG3525@1,COG3525@2	NA|NA|NA	G	Glycosyl hydrolase family 20, catalytic domain
MAG.T21.45_02283	1120968.AUBX01000011_gene3266	0.0	1131.7	Cytophagia													Bacteria	47JGS@768503,4NEIG@976,COG1629@1,COG4771@2	NA|NA|NA	P	TonB-dependent Receptor Plug
MAG.T21.45_02284	1121286.AUMT01000003_gene2027	3.4e-107	395.2	Chryseobacterium				ko:K15727					ko00000,ko02000	8.A.1.2.1			Bacteria	1HXZJ@117743,3ZQXB@59732,4NDW5@976,COG0845@1,COG0845@2	NA|NA|NA	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAG.T21.45_02285	929562.Emtol_2590	0.0	1746.9	Cytophagia	czcC			ko:K15725,ko:K15726					ko00000,ko02000	1.B.17.2.2,2.A.6.1.2			Bacteria	47JC4@768503,4P36A@976,COG1538@1,COG1538@2,COG3696@1,COG3696@2	NA|NA|NA	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MAG.T21.45_02286	402612.FP0879	1.6e-08	65.9	Flavobacterium													Bacteria	1IGI9@117743,2EAT9@1,2NX2D@237,334V5@2,4NUP8@976	NA|NA|NA		
MAG.T21.45_02288	760192.Halhy_2756	6e-65	254.2	Sphingobacteriia	yegX			ko:K07273					ko00000				Bacteria	1ISMY@117747,4NKHF@976,COG3757@1,COG3757@2	NA|NA|NA	M	PFAM Glycosyl hydrolases family 25
MAG.T21.45_02289	760192.Halhy_2755	7.2e-140	503.8	Sphingobacteriia	argD		2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1IQCC@117747,4NFMC@976,COG4992@1,COG4992@2	NA|NA|NA	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MAG.T21.45_02290	760192.Halhy_2589	2.4e-172	612.1	Sphingobacteriia	rpoN			ko:K03092	ko02020,ko05111,map02020,map05111				ko00000,ko00001,ko03021				Bacteria	1IQIK@117747,4NE5B@976,COG1508@1,COG1508@2	NA|NA|NA	K	RNA polymerase, sigma-54 factor
MAG.T21.45_02291	1122176.KB903542_gene360	1.1e-165	590.1	Sphingobacteriia	pepP		3.4.11.9	ko:K01262,ko:K02027		M00207			ko00000,ko00002,ko01000,ko01002,ko02000	3.A.1.1			Bacteria	1IPAF@117747,4NI1J@976,COG0006@1,COG0006@2	NA|NA|NA	E	Xaa-Pro aminopeptidase
MAG.T21.45_02292	1122176.KB903544_gene754	6.7e-126	457.2	Sphingobacteriia	rlmN		2.1.1.192	ko:K06941					ko00000,ko01000,ko03009				Bacteria	1IQMY@117747,4NFH5@976,COG0820@1,COG0820@2	NA|NA|NA	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MAG.T21.45_02293	1122176.KB903544_gene726	3.5e-126	458.0	Sphingobacteriia	adoK	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100		R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000			iAF987.Gmet_2683	Bacteria	1INMS@117747,4NFJ9@976,COG0524@1,COG0524@2	NA|NA|NA	G	PFAM pfkB family carbohydrate kinase
MAG.T21.45_02295	938709.AUSH02000021_gene1950	3e-18	100.1	Bacteroidetes													Bacteria	2CEJP@1,33JRU@2,4NZ54@976	NA|NA|NA		
MAG.T21.45_02296	1122176.KB903551_gene4228	1.7e-24	118.6	Sphingobacteriia	clpS	GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087		ko:K06891					ko00000				Bacteria	1IUIV@117747,4NS8R@976,COG2127@1,COG2127@2	NA|NA|NA	S	Clp protease adaptor protein ClpS
MAG.T21.45_02297	649349.Lbys_2887	6.8e-54	216.9	Cytophagia			1.11.1.15	ko:K03564					ko00000,ko01000				Bacteria	47PTD@768503,4NNHI@976,COG1225@1,COG1225@2	NA|NA|NA	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MAG.T21.45_02298	760192.Halhy_3992	1.2e-67	263.5	Sphingobacteriia													Bacteria	1IP6X@117747,4NE8D@976,COG0697@1,COG0697@2	NA|NA|NA	EG	PFAM EamA-like transporter family
MAG.T21.45_02299	760192.Halhy_3582	5.4e-273	946.8	Sphingobacteriia	ftsH			ko:K03798		M00742			ko00000,ko00002,ko01000,ko01002,ko03110				Bacteria	1IQ2Z@117747,4NF0E@976,COG0465@1,COG0465@2	NA|NA|NA	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MAG.T21.45_02300	1122176.KB903565_gene3296	3.3e-33	147.9	Sphingobacteriia	rsfS	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	2.7.7.18	ko:K00969,ko:K09710	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009				Bacteria	1ISS0@117747,4NSKK@976,COG0799@1,COG0799@2	NA|NA|NA	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MAG.T21.45_02301	1313421.JHBV01000013_gene3757	6.9e-35	154.5	Sphingobacteriia	birA		6.3.4.15	ko:K03523,ko:K03524	ko00780,ko01100,ko02010,map00780,map01100,map02010	M00581,M00582	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	2.A.88.1,2.A.88.2			Bacteria	1IS0E@117747,4NHCH@976,COG0340@1,COG0340@2	NA|NA|NA	H	PFAM Biotin lipoate A B protein ligase
MAG.T21.45_02302	760192.Halhy_3579	9.3e-106	390.6	Sphingobacteriia	cinA		3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760		R02322	RC00100	ko00000,ko00001,ko01000				Bacteria	1INYU@117747,4NDVV@976,COG1058@1,COG1058@2,COG1546@1,COG1546@2	NA|NA|NA	S	Belongs to the CinA family
MAG.T21.45_02303	760192.Halhy_3578	4.5e-140	504.6	Sphingobacteriia	bfmBB		2.3.1.168,2.3.1.61	ko:K00658,ko:K09699	ko00020,ko00280,ko00310,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00280,map00310,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00036	R02570,R02571,R02662,R03174,R04097,R08549,R10998	RC00004,RC02727,RC02833,RC02870	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1IP3U@117747,4NED0@976,COG0508@1,COG0508@2	NA|NA|NA	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MAG.T21.45_02304	760192.Halhy_3266	3.4e-86	326.2	Sphingobacteriia													Bacteria	1J19F@117747,4P298@976,COG0457@1,COG0457@2	NA|NA|NA	S	WD40-like Beta Propeller Repeat
MAG.T21.45_02305	760192.Halhy_2757	3e-159	568.2	Sphingobacteriia													Bacteria	1ISZC@117747,4NDV1@976,COG2133@1,COG2133@2	NA|NA|NA	G	Glucose / Sorbosone dehydrogenase
MAG.T21.45_02306	760192.Halhy_3371	5.8e-183	647.1	Sphingobacteriia	ugd		1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQ5C@117747,4NE00@976,COG1004@1,COG1004@2	NA|NA|NA	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MAG.T21.45_02307	760192.Halhy_3370	6.1e-07	61.2	Sphingobacteriia													Bacteria	1IUCU@117747,4NMDX@976,COG2849@1,COG2849@2	NA|NA|NA	S	MORN repeat variant
MAG.T21.45_02308	1177179.A11A3_12368	7.2e-24	116.3	Oceanospirillales													Bacteria	1MZK1@1224,1S9TU@1236,1XPWS@135619,2D2Z4@1,32TDX@2	NA|NA|NA	S	Protein of unknown function (DUF3024)
MAG.T21.45_02309	497965.Cyan7822_2451	2.5e-22	110.9	Cyanothece													Bacteria	1GA2B@1117,3KJ0I@43988,COG1598@1,COG1598@2	NA|NA|NA	S	PFAM Uncharacterised protein family UPF0150
MAG.T21.45_02310	103690.17133498	8.6e-22	109.4	Nostocales													Bacteria	1GAC3@1117,1HPNS@1161,COG1724@1,COG1724@2	NA|NA|NA	N	mRNA binding
MAG.T21.45_02312	760192.Halhy_3369	2.5e-84	319.3	Sphingobacteriia	porQ												Bacteria	1IXQD@117747,4NHNC@976,COG2067@1,COG2067@2	NA|NA|NA	I	penicillin-binding protein
MAG.T21.45_02313	313598.MED152_03035	8.2e-67	260.4	Polaribacter	ermC												Bacteria	1HZ4P@117743,3VX33@52959,4PM6H@976,COG0500@1,COG2226@2	NA|NA|NA	Q	O-methyltransferase
MAG.T21.45_02314	760192.Halhy_2990	0.0	1075.1	Sphingobacteriia	thrA	GO:0003674,GO:0003824,GO:0004072,GO:0004412,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009090,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.3,2.7.2.4	ko:K00003,ko:K00928,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000			iECDH1ME8569_1439.ECDH1ME8569_0002,iEcDH1_1363.EcDH1_3594,iSFV_1184.SFV_0001	Bacteria	1IQEK@117747,4NFGR@976,COG0460@1,COG0460@2,COG0527@1,COG0527@2	NA|NA|NA	E	homoserine dehydrogenase
MAG.T21.45_02315	760192.Halhy_2991	2.1e-99	369.0	Sphingobacteriia	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000			iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545,iSB619.SA_RS06620	Bacteria	1IP1D@117747,4NE2M@976,COG0083@1,COG0083@2	NA|NA|NA	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MAG.T21.45_02316	1122179.KB890491_gene4380	2.6e-146	525.4	Sphingobacteriia	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000			iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025	Bacteria	1IPDH@117747,4NEAA@976,COG0498@1,COG0498@2	NA|NA|NA	E	Threonine synthase
MAG.T21.45_02317	1313421.JHBV01000042_gene3372	8.7e-82	310.8	Sphingobacteriia			2.4.1.52	ko:K00712,ko:K13004					ko00000,ko01000,ko01003,ko01005		GT4		Bacteria	1IT3G@117747,4NEX8@976,COG0438@1,COG0438@2	NA|NA|NA	M	COG0438 Glycosyltransferase
MAG.T21.45_02318	485918.Cpin_4745	2.8e-24	119.8	Sphingobacteriia													Bacteria	1IUGI@117747,4NNXT@976,COG1835@1,COG1835@2	NA|NA|NA	I	Acyltransferase family
MAG.T21.45_02319	714943.Mucpa_1111	2e-19	102.4	Sphingobacteriia													Bacteria	1IUDI@117747,4NQAY@976,COG4270@1,COG4270@2	NA|NA|NA	S	COGs COG4270 membrane protein
MAG.T21.45_02320	1122605.KB893649_gene3740	9.7e-142	510.4	Sphingobacteriia			3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1IZN8@117747,4PIVJ@976,COG3540@1,COG3540@2	NA|NA|NA	P	PhoD-like phosphatase
MAG.T21.45_02321	760192.Halhy_3691	4e-43	182.6	Bacteria													Bacteria	COG0438@1,COG0438@2	NA|NA|NA	M	transferase activity, transferring glycosyl groups
MAG.T21.45_02322	6669.EFX74634	8.5e-12	77.8	Arthropoda			2.4.1.50	ko:K11703	ko00310,ko00514,map00310,map00514		R03380	RC00005,RC00397	ko00000,ko00001,ko01000,ko01003		GT25		Arthropoda	38BZB@33154,3BB9G@33208,3CT83@33213,41Y8I@6656,KOG4179@1,KOG4179@2759	NA|NA|NA	O	Glycosyltransferase 25 family
MAG.T21.45_02323	56110.Oscil6304_3541	9e-26	124.4	Oscillatoriales				ko:K20444					ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4		Bacteria	1G09N@1117,1H8HE@1150,COG1216@1,COG1216@2	NA|NA|NA	S	PFAM Glycosyl transferase family 2
MAG.T21.45_02324	525257.HMPREF0204_10627	8.1e-30	137.9	Chryseobacterium													Bacteria	1I8D0@117743,3ZQ24@59732,4NU2D@976,COG1215@1,COG1215@2	NA|NA|NA	M	Capsular biosynthesis protein CpsI
MAG.T21.45_02325	869213.JCM21142_93667	2.6e-41	176.0	Cytophagia													Bacteria	47SJI@768503,4NKAZ@976,COG1216@1,COG1216@2	NA|NA|NA	S	Glycosyltransferase like family 2
MAG.T21.45_02326	1340493.JNIF01000004_gene99	1.9e-84	319.7	Acidobacteria	gltP			ko:K03309,ko:K11102					ko00000,ko02000	2.A.23,2.A.23.1.1,2.A.23.1.2			Bacteria	3Y2G6@57723,COG1301@1,COG1301@2	NA|NA|NA	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MAG.T21.45_02327	760192.Halhy_2995	5.1e-307	1060.1	Sphingobacteriia													Bacteria	1INVS@117747,4NE13@976,COG0308@1,COG0308@2	NA|NA|NA	E	COG0308 Aminopeptidase N
MAG.T21.45_02328	760192.Halhy_2997	2.5e-99	369.0	Bacteroidetes	mvaD		4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000				Bacteria	4NDYX@976,COG3407@1,COG3407@2	NA|NA|NA	I	diphosphomevalonate decarboxylase
MAG.T21.45_02329	1166018.FAES_0862	4.8e-35	154.5	Cytophagia													Bacteria	47Q3A@768503,4NQ61@976,COG0607@1,COG0607@2	NA|NA|NA	P	Rhodanese Homology Domain
MAG.T21.45_02330	760192.Halhy_2998	3.8e-184	651.0	Sphingobacteriia	kbl		2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1IQY7@117747,4NFRY@976,COG0156@1,COG0156@2	NA|NA|NA	E	PFAM Aminotransferase class I and II
MAG.T21.45_02331	1121887.AUDK01000021_gene964	3.6e-106	391.0	Flavobacterium			3.1.21.4	ko:K01155					ko00000,ko01000,ko02048				Bacteria	1I7F0@117743,2BYXQ@1,2NYK9@237,2Z8ZA@2,4NJGY@976	NA|NA|NA	L	ApaLI-like restriction endonuclease
MAG.T21.45_02332	1121887.AUDK01000021_gene965	1.2e-204	719.2	Flavobacterium			2.1.1.72	ko:K00571,ko:K07316					ko00000,ko01000,ko02048				Bacteria	1I9UF@117743,2NXV7@237,4NHTG@976,COG2189@1,COG2189@2	NA|NA|NA	L	DNA methylase
MAG.T21.45_02333	1233951.IO90_05255	3.7e-29	134.0	Flavobacteriia		GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0045926,GO:0045927,GO:0046483,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0065007,GO:0070482,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360											Bacteria	1I24W@117743,4NPPR@976,COG4679@1,COG4679@2	NA|NA|NA	S	Phage derived protein Gp49-like (DUF891)
MAG.T21.45_02334	1288963.ADIS_1578	3.9e-42	177.2	Cytophagia													Bacteria	47XUU@768503,4NTK9@976,COG1396@1,COG1396@2	NA|NA|NA	K	Helix-turn-helix XRE-family like proteins
MAG.T21.45_02337	388413.ALPR1_18083	0.0	1305.8	Cytophagia													Bacteria	47JPK@768503,4NESU@976,COG4447@1,COG4447@2	NA|NA|NA	S	Sortilin, neurotensin receptor 3,
MAG.T21.45_02338	880070.Cycma_5031	5.2e-59	234.2	Cytophagia													Bacteria	47PJ0@768503,4NFEG@976,COG3145@1,COG3145@2	NA|NA|NA	L	Alkylated DNA repair protein
MAG.T21.45_02339	1443665.JACA01000001_gene2654	5.6e-22	111.7	Aquimarina													Bacteria	1I1KI@117743,28S9Y@1,2YGHP@290174,2ZEM4@2,4NN2V@976	NA|NA|NA		
MAG.T21.45_02341	938709.AUSH02000067_gene2022	7.6e-60	236.9	Bacteroidetes	btuE		1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918		R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000				Bacteria	4NM6G@976,COG0386@1,COG0386@2	NA|NA|NA	O	Belongs to the glutathione peroxidase family
MAG.T21.45_02342	1123276.KB893249_gene420	2.4e-135	488.8	Cytophagia				ko:K05820					ko00000,ko02000	2.A.1.27			Bacteria	47M36@768503,4PKJD@976,COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
MAG.T21.45_02343	1185876.BN8_02492	7.3e-116	423.7	Cytophagia													Bacteria	47JT2@768503,4NG75@976,COG1082@1,COG1082@2	NA|NA|NA	G	Xylose isomerase domain protein TIM barrel
MAG.T21.45_02344	929703.KE386491_gene2777	4.4e-114	418.3	Cytophagia													Bacteria	28N7K@1,2ZBC9@2,47N9I@768503,4NHU8@976	NA|NA|NA	S	Copper type II ascorbate-dependent monooxygenase, C-terminal domain
MAG.T21.45_02345	760192.Halhy_6348	3.5e-98	365.2	Sphingobacteriia													Bacteria	1IQ3K@117747,4NEEZ@976,COG1012@1,COG1012@2	NA|NA|NA	C	acyl-CoA reductase
MAG.T21.45_02346	62928.azo3132	1.6e-33	149.4	Rhodocyclales				ko:K09941					ko00000				Bacteria	1RDE0@1224,2KW6Y@206389,2VQ9D@28216,COG3310@1,COG3310@2	NA|NA|NA	S	Protein of unknown function (DUF1415)
MAG.T21.45_02347	760192.Halhy_6347	2.2e-121	442.2	Sphingobacteriia	rluD	GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180					ko00000,ko01000,ko03009,ko03016			iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432	Bacteria	1IP51@117747,4NEV3@976,COG0564@1,COG0564@2	NA|NA|NA	J	Responsible for synthesis of pseudouridine from uracil
MAG.T21.45_02348	1453500.AT05_00755	4.5e-92	344.4	Flavobacteriia	XK27_05675												Bacteria	1IKKB@117743,4PN8M@976,COG4947@1,COG4947@2	NA|NA|NA	S	Putative esterase
MAG.T21.45_02349	1121904.ARBP01000018_gene2605	5.8e-210	737.3	Cytophagia	acd		1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212		R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000				Bacteria	47MIF@768503,4NEM4@976,COG1960@1,COG1960@2	NA|NA|NA	I	Acetyl-CoA dehydrogenase C-terminal like
MAG.T21.45_02350	760192.Halhy_4640	8.1e-219	766.5	Sphingobacteriia	pruA		1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100		R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000				Bacteria	1IQEH@117747,4NFTW@976,COG1012@1,COG1012@2	NA|NA|NA	C	Aldehyde dehydrogenase family
MAG.T21.45_02351	1122179.KB890497_gene2856	1.1e-59	236.1	Sphingobacteriia	coaD		2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	1ISUA@117747,4NM84@976,COG0669@1,COG0669@2	NA|NA|NA	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MAG.T21.45_02352	760192.Halhy_0090	7.8e-28	130.6	Bacteroidetes													Bacteria	2BZC9@1,32R4S@2,4NQX4@976	NA|NA|NA		
MAG.T21.45_02353	1165841.SULAR_09584	3.8e-58	231.1	Epsilonproteobacteria	purE	GO:0008150,GO:0040007	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000			iJN678.purE,iNJ661.Rv3275c	Bacteria	1RCWJ@1224,2YNW0@29547,42QTK@68525,COG0041@1,COG0041@2	NA|NA|NA	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MAG.T21.45_02354	509635.N824_19115	8.2e-62	243.8	Sphingobacteriia	neuA		2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100		R01117,R04215	RC00152	ko00000,ko00001,ko01000				Bacteria	1ISWB@117747,4NHBT@976,COG2755@1,COG2755@2	NA|NA|NA	E	GDSL-like Lipase/Acylhydrolase
MAG.T21.45_02355	760192.Halhy_0857	1.2e-114	419.9	Sphingobacteriia	yjfJ	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464		ko:K03969					ko00000				Bacteria	1IZFV@117747,4NIZP@976,COG1842@1,COG1842@2	NA|NA|NA	KT	Phage shock protein A
MAG.T21.45_02356	1122176.KB903619_gene5327	1.9e-29	136.0	Sphingobacteriia													Bacteria	1IZIZ@117747,2AF9A@1,3158F@2,4PJGJ@976	NA|NA|NA		
MAG.T21.45_02357	1122176.KB903540_gene87	1.2e-74	287.0	Sphingobacteriia													Bacteria	1IWXV@117747,4NH6C@976,COG2819@1,COG2819@2	NA|NA|NA	S	Putative esterase
MAG.T21.45_02358	1089547.KB913013_gene3110	1.6e-107	396.4	Cytophagia	hsvB		6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502		R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	47MVS@768503,4NGM6@976,COG1181@1,COG1181@2	NA|NA|NA	M	ATP-grasp domain
MAG.T21.45_02359	760192.Halhy_5129	4.2e-175	621.7	Sphingobacteriia													Bacteria	1IQD7@117747,4NEPT@976,COG0612@1,COG0612@2	NA|NA|NA	S	Peptidase M16 inactive domain
MAG.T21.45_02360	760192.Halhy_5130	6.4e-152	543.9	Sphingobacteriia				ko:K07263					ko00000,ko01000,ko01002				Bacteria	1IPY5@117747,4NEDZ@976,COG0612@1,COG0612@2	NA|NA|NA	S	PFAM Peptidase M16 inactive domain
MAG.T21.45_02361	760192.Halhy_2469	2.6e-304	1050.8	Sphingobacteriia	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1IPWX@117747,4NEFT@976,COG0441@1,COG0441@2	NA|NA|NA	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MAG.T21.45_02362	760192.Halhy_3094	1.5e-172	612.8	Sphingobacteriia	prc		3.4.21.102	ko:K03797					ko00000,ko01000,ko01002				Bacteria	1IQA9@117747,4NDWU@976,COG0793@1,COG0793@2	NA|NA|NA	M	Belongs to the peptidase S41A family
MAG.T21.45_02363	1122176.KB903548_gene1206	1.2e-63	250.0	Sphingobacteriia	ybfF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0016790,GO:0044424,GO:0044444,GO:0044464,GO:0052689		ko:K01175					ko00000,ko01000				Bacteria	1IX9D@117747,4NDZI@976,COG0596@1,COG0596@2	NA|NA|NA	S	Alpha beta hydrolase
MAG.T21.45_02364	760192.Halhy_3092	4.3e-52	211.5	Sphingobacteriia	crtA		1.14.15.9	ko:K09847	ko00906,ko01100,map00906,map01100		R07525,R07526,R07537,R07538	RC02084	ko00000,ko00001,ko01000				Bacteria	1IS42@117747,29UQ5@1,30G1W@2,4NKX5@976	NA|NA|NA	Q	spheroidene monooxygenase
MAG.T21.45_02365	760192.Halhy_6293	1.9e-177	630.9	Sphingobacteriia													Bacteria	1IYSQ@117747,4P8KP@976,COG3210@1,COG3210@2	NA|NA|NA	U	IMG reference gene
MAG.T21.45_02366	1121904.ARBP01000015_gene173	1.8e-136	492.7	Cytophagia													Bacteria	47K7H@768503,4NGHJ@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_02367	760192.Halhy_3115	5.9e-296	1023.1	Sphingobacteriia	uvrB	GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391		ko:K03702	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	1INSY@117747,4NE6E@976,COG0556@1,COG0556@2	NA|NA|NA	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MAG.T21.45_02368	56107.Cylst_4668	6.2e-37	160.2	Nostocales													Bacteria	1G79B@1117,1HNFV@1161,COG0614@1,COG0614@2	NA|NA|NA	P	PD-(D/E)XK nuclease superfamily
MAG.T21.45_02369	760192.Halhy_3537	4.1e-115	421.0	Sphingobacteriia													Bacteria	1IW51@117747,4NFNA@976,COG2013@1,COG2013@2	NA|NA|NA	S	Mitochondrial biogenesis AIM24
MAG.T21.45_02370	1122176.KB903540_gene94	6.8e-84	317.8	Sphingobacteriia			2.4.1.349	ko:K12994					ko00000,ko01000,ko01003,ko01005		GT4		Bacteria	1ITGA@117747,4NETA@976,COG0438@1,COG0438@2	NA|NA|NA	M	PFAM Glycosyl transferase, group 1
MAG.T21.45_02371	1122176.KB903571_gene4791	3.3e-178	631.3	Sphingobacteriia	yqeV	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707			R10649	RC00003,RC03221	ko00000,ko01000,ko03016				Bacteria	1INWM@117747,4NE0R@976,COG0621@1,COG0621@2	NA|NA|NA	J	2-methylthioadenine synthetase
MAG.T21.45_02372	1250278.JQNQ01000001_gene3728	2.5e-76	292.4	Flavobacteriia			3.4.11.2,3.5.2.6	ko:K01256,ko:K17836	ko00311,ko00480,ko01100,ko01130,ko01501,map00311,map00480,map01100,map01130,map01501	M00627,M00628	R00899,R04951,R06363	RC00096,RC00141,RC01499	ko00000,ko00001,ko00002,ko01000,ko01002,ko01504				Bacteria	1I0I0@117743,4PDG3@976,COG2367@1,COG2367@2	NA|NA|NA	V	Beta-lactamase enzyme family
MAG.T21.45_02373	760192.Halhy_2688	1.6e-210	740.0	Sphingobacteriia	dnaQ2		3.6.4.12	ko:K03657,ko:K07465	ko03420,ko03430,map03420,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	1IPF7@117747,4NIIR@976,COG0210@1,COG0210@2,COG2887@1,COG2887@2	NA|NA|NA	L	Belongs to the helicase family. UvrD subfamily
MAG.T21.45_02374	760192.Halhy_3596	7.7e-167	594.0	Sphingobacteriia	dnaX		2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1IQ35@117747,4NE8A@976,COG2812@1,COG2812@2	NA|NA|NA	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MAG.T21.45_02375	760192.Halhy_3598	7.4e-228	796.6	Sphingobacteriia	nadE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPN6@117747,4NEXG@976,COG0171@1,COG0171@2,COG0388@1,COG0388@2	NA|NA|NA	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MAG.T21.45_02376	1358423.N180_14520	8.7e-09	66.6	Sphingobacteriia													Bacteria	1IZZY@117747,2CGNP@1,31TDH@2,4PJC7@976	NA|NA|NA		
MAG.T21.45_02377	760192.Halhy_3100	8.8e-269	932.6	Sphingobacteriia	yjjK	GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	3.6.3.25	ko:K06020					ko00000,ko01000				Bacteria	1IQQ4@117747,4NES5@976,COG0488@1,COG0488@2	NA|NA|NA	S	ABC transporter
MAG.T21.45_02379	1089547.KB913013_gene4136	2.6e-167	595.1	Cytophagia	dctA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K11103	ko02020,map02020				ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7			Bacteria	47JTF@768503,4NDUU@976,COG1301@1,COG1301@2	NA|NA|NA	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MAG.T21.45_02380	760192.Halhy_0649	2.3e-163	582.0	Sphingobacteriia													Bacteria	1IRE2@117747,4NF9W@976,COG0671@1,COG0671@2	NA|NA|NA	I	PAP2 superfamily
MAG.T21.45_02381	760192.Halhy_0650	0.0	1509.2	Sphingobacteriia													Bacteria	1IP40@117747,4NEE8@976,COG4888@1,COG4888@2	NA|NA|NA	S	SPTR ASPIC UnbV domain protein
MAG.T21.45_02382	760192.Halhy_0651	1.3e-302	1045.0	Sphingobacteriia	tdk		2.7.1.21	ko:K00857,ko:K21572	ko00240,ko00983,ko01100,map00240,map00983,map01100		R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000,ko02000	8.A.46.1,8.A.46.3			Bacteria	1INRJ@117747,4NE0A@976,COG1435@1,COG1435@2	NA|NA|NA	F	PFAM RagB SusD
MAG.T21.45_02383	760192.Halhy_0652	0.0	1793.1	Sphingobacteriia													Bacteria	1INPI@117747,4NDXS@976,COG1629@1,COG1629@2	NA|NA|NA	P	PFAM TonB-dependent Receptor Plug
MAG.T21.45_02384	313596.RB2501_00976	8e-84	317.0	Flavobacteriia													Bacteria	1I22H@117743,4NF64@976,COG1028@1,COG1028@2	NA|NA|NA	IQ	KR domain
MAG.T21.45_02385	657309.BXY_31950	4.2e-11	73.2	Bacteroidaceae				ko:K07133					ko00000				Bacteria	2FQM0@200643,4AQ8M@815,4NHQG@976,COG1373@1,COG1373@2	NA|NA|NA	S	Domain of unknown function (DUF4143)
MAG.T21.45_02386	1123234.AUKI01000011_gene1286	1.2e-189	669.5	Flavobacteriia	ybjT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944											Bacteria	1HY1N@117743,4NEJF@976,COG0702@1,COG0702@2	NA|NA|NA	GM	epimerase
MAG.T21.45_02387	761193.Runsl_3847	0.0	1243.4	Cytophagia	hyuA	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016885,GO:0017144,GO:0018710,GO:0042180,GO:0043443,GO:0044237,GO:0044281,GO:0071704,GO:1901568,GO:1902224	3.5.2.14,3.5.2.9,6.4.1.6,6.4.1.8	ko:K01469,ko:K01473,ko:K01474,ko:K10701,ko:K10855	ko00330,ko00480,ko00642,ko01100,ko01120,ko01220,map00330,map00480,map00642,map01100,map01120,map01220		R00251,R03187,R05453	RC00040,RC00553,RC00632	ko00000,ko00001,ko01000			iNJ661.Rv0266c	Bacteria	47K85@768503,4NFBV@976,COG0145@1,COG0145@2,COG0146@1,COG0146@2	NA|NA|NA	EQ	Hydantoinase/oxoprolinase
MAG.T21.45_02388	1449353.JQMQ01000005_gene2307	7.9e-11	74.7	Streptacidiphilus													Bacteria	2GJED@201174,2NH1A@228398,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat
MAG.T21.45_02389	760192.Halhy_2965	1.4e-85	323.6	Sphingobacteriia	hemY												Bacteria	1IX8H@117747,4NEPC@976,COG1232@1,COG1232@2	NA|NA|NA	H	Flavin containing amine oxidoreductase
MAG.T21.45_02390	1123278.KB893567_gene2051	0.0	1285.4	Cytophagia													Bacteria	47JJS@768503,4NDXS@976,COG1629@1,COG1629@2,COG4206@1,COG4206@2	NA|NA|NA	P	TonB-dependent Receptor Plug
MAG.T21.45_02391	1185876.BN8_01507	5.9e-200	703.7	Cytophagia				ko:K21572					ko00000,ko02000	8.A.46.1,8.A.46.3			Bacteria	47MFF@768503,4NFQ7@976,COG1834@1,COG1834@2	NA|NA|NA	E	SusD family
MAG.T21.45_02392	929703.KE386491_gene476	6.6e-59	234.2	Cytophagia	yfiH	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944		ko:K05810					ko00000,ko01000				Bacteria	47JW0@768503,4NM9H@976,COG1496@1,COG1496@2	NA|NA|NA	S	Belongs to the multicopper oxidase YfiH RL5 family
MAG.T21.45_02393	1121875.KB907551_gene959	5.9e-175	621.3	Flavobacteriia				ko:K03306					ko00000	2.A.20			Bacteria	1HYA8@117743,4NFCB@976,COG0306@1,COG0306@2	NA|NA|NA	U	phosphate transporter
MAG.T21.45_02394	760192.Halhy_3600	1.5e-38	166.4	Bacteroidetes			2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000				Bacteria	4PNQP@976,COG1208@1,COG1208@2	NA|NA|NA	JM	Hexapeptide repeat of succinyl-transferase
MAG.T21.45_02395	211586.SO_4343	3.7e-141	508.1	Shewanellaceae	spt		2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1MWHJ@1224,1RMNR@1236,2Q9HJ@267890,COG0075@1,COG0075@2	NA|NA|NA	E	PFAM aminotransferase class V
MAG.T21.45_02396	1406840.Q763_08945	3.2e-158	565.1	Flavobacterium			3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142		R01498	RC00059,RC00451	ko00000,ko00001,ko01000		GH30		Bacteria	1HZ2G@117743,2NSZB@237,4NF4C@976,COG5520@1,COG5520@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 30 family
MAG.T21.45_02397	1121481.AUAS01000005_gene2037	2.9e-118	431.8	Cytophagia													Bacteria	47Y99@768503,4PMA9@976,COG2010@1,COG2010@2	NA|NA|NA	C	Domain of Unknown Function (DUF1080)
MAG.T21.45_02398	1111730.ATTM01000006_gene2572	1.2e-48	199.9	Flavobacterium													Bacteria	1ID6J@117743,2NXHH@237,4PAWG@976,COG2304@1,COG2304@2	NA|NA|NA	S	von Willebrand factor (vWF) type A domain
MAG.T21.45_02399	1111730.ATTM01000006_gene2573	4.7e-50	205.3	Flavobacterium													Bacteria	1IN8E@117743,2BK13@1,2NYFB@237,32EE8@2,4PA86@976	NA|NA|NA		
MAG.T21.45_02400	1122179.KB890416_gene2726	2.1e-148	532.3	Sphingobacteriia	nhaD												Bacteria	1IVHN@117747,4NGP4@976,COG1055@1,COG1055@2	NA|NA|NA	P	COG1055 Na H antiporter NhaD and related arsenite
MAG.T21.45_02401	485917.Phep_3489	5.5e-172	610.9	Sphingobacteriia			3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821		ko00000,ko00001,ko00002,ko01000				Bacteria	1IQA2@117747,4NFGI@976,COG3119@1,COG3119@2	NA|NA|NA	P	Sulfatase
MAG.T21.45_02402	756272.Plabr_0079	1e-166	593.6	Planctomycetes	atsA		3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600		R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000				Bacteria	2IWVY@203682,COG3119@1,COG3119@2	NA|NA|NA	P	COG3119 Arylsulfatase A and related enzymes
MAG.T21.45_02403	1492737.FEM08_09530	5.1e-114	417.9	Flavobacterium													Bacteria	1HYCD@117743,2NV7P@237,4NF12@976,COG4677@1,COG4677@2	NA|NA|NA	G	Domain of unknown function (DUF4861)
MAG.T21.45_02404	688270.Celal_1430	2.5e-79	302.8	Cellulophaga													Bacteria	1F9X3@104264,1IEN9@117743,2DB7P@1,2Z7MR@2,4NKTK@976	NA|NA|NA		
MAG.T21.45_02405	641524.ADICYQ_2559	2.7e-73	283.1	Bacteroidetes	lppC	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944		ko:K06910					ko00000				Bacteria	4NKRU@976,COG1881@1,COG1881@2	NA|NA|NA	S	YHYH protein
MAG.T21.45_02406	1278307.KB906975_gene1849	1.4e-31	144.1	Gammaproteobacteria			2.7.11.1	ko:K12132					ko00000,ko01000,ko01001				Bacteria	1R6GS@1224,1S5ET@1236,COG1262@1,COG1262@2	NA|NA|NA	C	Protein of unknown function (DUF1566)
MAG.T21.45_02407	1229487.AMYW01000011_gene3568	8.8e-50	203.0	Flavobacterium	vapC			ko:K18828					ko00000,ko01000,ko02048,ko03016				Bacteria	1I9W7@117743,2NYUF@237,4NSBY@976,COG1487@1,COG1487@2	NA|NA|NA	S	DNA-binding protein
MAG.T21.45_02408	866536.Belba_2966	1.5e-15	88.6	Cytophagia													Bacteria	2ED1Y@1,336YW@2,47T3J@768503,4NWIN@976	NA|NA|NA		
MAG.T21.45_02409	236814.IX39_19880	5.5e-17	95.5	Bacteria				ko:K21449					ko00000,ko02000	1.B.40.2			Bacteria	COG1511@1,COG1511@2	NA|NA|NA	Q	domain protein
MAG.T21.45_02410	269798.CHU_2926	3.8e-22	112.5	Cytophagia													Bacteria	47P6I@768503,4NM6Q@976,COG3064@1,COG3064@2	NA|NA|NA	M	Type IX secretion system membrane protein PorP/SprF
MAG.T21.45_02411	1237149.C900_04169	1.6e-66	261.5	Cytophagia				ko:K21571					ko00000				Bacteria	47PJR@768503,4NHDQ@976,COG3656@1,COG3656@2,COG5563@1,COG5563@2	NA|NA|NA	G	Fibronectin type III domain protein
MAG.T21.45_02412	1443665.JACA01000056_gene3204	3.5e-47	195.3	Flavobacteriia	cah		4.2.1.1	ko:K01674	ko00910,map00910		R00132,R10092	RC02807	ko00000,ko00001,ko01000				Bacteria	1I11S@117743,4NK9J@976,COG3338@1,COG3338@2	NA|NA|NA	P	Eukaryotic-type carbonic anhydrase
MAG.T21.45_02414	1236976.JCM16418_4253	5.4e-49	202.2	Paenibacillaceae	phoX		3.2.1.4,3.2.1.78,3.2.1.8	ko:K01179,ko:K01181,ko:K01218,ko:K07093	ko00051,ko00500,ko01100,ko02024,map00051,map00500,map01100,map02024		R01332,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000		GH26,GH5,GH9		Bacteria	1V7PQ@1239,277JF@186822,4IUC5@91061,COG1409@1,COG1409@2,COG2041@1,COG2041@2,COG3211@1,COG3211@2,COG4733@1,COG4733@2	NA|NA|NA	G	Fibronectin type III domain
MAG.T21.45_02415	1250278.JQNQ01000001_gene2191	3.5e-06	60.1	Bacteria													Bacteria	COG4974@1,COG4974@2	NA|NA|NA	L	Belongs to the 'phage' integrase family
MAG.T21.45_02417	1300143.CCAV010000010_gene3087	3.5e-13	82.0	Chryseobacterium			2.1.1.113,2.1.1.72	ko:K00571,ko:K00590					ko00000,ko01000,ko02048				Bacteria	1IKZP@117743,3ZTE4@59732,4PIRI@976,COG0863@1,COG0863@2	NA|NA|NA	L	DNA methylase
MAG.T21.45_02418	760192.Halhy_2811	7.1e-102	377.5	Sphingobacteriia	yfiQ	GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120		R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004				Bacteria	1IVTU@117747,4NFTI@976,COG0045@1,COG0045@2,COG1042@1,COG1042@2,COG1670@1,COG1670@2	NA|NA|NA	C	CoA binding domain
MAG.T21.45_02419	760192.Halhy_2139	2.8e-159	568.2	Sphingobacteriia													Bacteria	1IWYY@117747,4NG9U@976,COG2159@1,COG2159@2	NA|NA|NA	S	Amidohydrolase
MAG.T21.45_02420	760192.Halhy_4055	1.1e-63	250.8	Sphingobacteriia				ko:K06872					ko00000				Bacteria	1IR79@117747,4NHBG@976,COG1512@1,COG1512@2	NA|NA|NA	S	TPM domain
MAG.T21.45_02421	760192.Halhy_3413	1.3e-108	399.8	Sphingobacteriia	pyrD	GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000			iEC042_1314.EC042_1029,iECIAI39_1322.ECIAI39_2202,iECUMN_1333.ECUMN_1134,iEcSMS35_1347.EcSMS35_2174,iPC815.YPO1415,iYL1228.KPN_00974	Bacteria	1IPRM@117747,4NDVB@976,COG0167@1,COG0167@2	NA|NA|NA	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
MAG.T21.45_02422	760192.Halhy_3330	3.5e-81	308.1	Sphingobacteriia													Bacteria	1IP15@117747,4NF1I@976,COG0745@1,COG0745@2	NA|NA|NA	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MAG.T21.45_02423	760192.Halhy_3331	3.7e-124	451.8	Sphingobacteriia													Bacteria	1IS7E@117747,4NEFW@976,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
MAG.T21.45_02424	760192.Halhy_1986	0.0	2934.4	Sphingobacteriia	greA												Bacteria	1INS4@117747,4NEB8@976,COG1747@1,COG1747@2	NA|NA|NA	S	Motility related/secretion protein
MAG.T21.45_02425	1122176.KB903543_gene689	1.9e-61	242.3	Sphingobacteriia	ruvA	GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03550	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1IQBR@117747,4NF4E@976,COG0632@1,COG0632@2	NA|NA|NA	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MAG.T21.45_02426	1202532.FF52_12001	1.9e-138	499.2	Flavobacterium	purD		6.3.4.13,6.3.5.3	ko:K01945,ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04463	RC00010,RC00090,RC00166,RC01160	ko00000,ko00001,ko00002,ko01000				Bacteria	1HXGE@117743,2NT4N@237,4NEUN@976,COG0151@1,COG0151@2	NA|NA|NA	F	Belongs to the GARS family
MAG.T21.45_02427	760192.Halhy_3971	2.6e-179	635.6	Sphingobacteriia			5.2.1.8	ko:K03769,ko:K03771					ko00000,ko01000,ko03110				Bacteria	1IPZ1@117747,4NGIR@976,COG0760@1,COG0760@2	NA|NA|NA	O	PPIC-type PPIASE domain
MAG.T21.45_02428	760192.Halhy_3972	7.1e-57	227.6	Sphingobacteriia	epsD		5.2.1.8	ko:K03771					ko00000,ko01000,ko03110				Bacteria	1IYQF@117747,4NG2P@976,COG0760@1,COG0760@2	NA|NA|NA	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MAG.T21.45_02429	760192.Halhy_3973	1.6e-164	585.9	Sphingobacteriia	surA		5.2.1.8	ko:K03771					ko00000,ko01000,ko03110				Bacteria	1IQB4@117747,4NEW0@976,COG0760@1,COG0760@2	NA|NA|NA	O	peptidylprolyl isomerase
MAG.T21.45_02430	1150600.ADIARSV_2574	6.2e-173	614.4	Sphingobacteriia													Bacteria	1IP8J@117747,4NEIY@976,COG1297@1,COG1297@2	NA|NA|NA	S	OPT oligopeptide transporter protein
MAG.T21.45_02431	555500.I215_15003	2.4e-151	542.3	Flavobacteriia				ko:K03305					ko00000	2.A.17			Bacteria	1HWTF@117743,4NE8R@976,COG3104@1,COG3104@2	NA|NA|NA	E	amino acid peptide transporter
MAG.T21.45_02432	760192.Halhy_2081	5.9e-53	214.2	Bacteroidetes													Bacteria	28JKT@1,2Z9DG@2,4NJJK@976	NA|NA|NA	S	Protein of unknown function (DUF4230)
MAG.T21.45_02433	485918.Cpin_5581	9.1e-198	696.4	Sphingobacteriia	gcs2												Bacteria	1INRP@117747,4NFMN@976,COG2308@1,COG2308@2	NA|NA|NA	S	Circularly permuted ATP-grasp type 2
MAG.T21.45_02434	1144313.PMI10_02610	6.2e-70	271.2	Flavobacterium	MA20_32425												Bacteria	1I040@117743,2NUS5@237,4NHIB@976,COG2307@1,COG2307@2	NA|NA|NA	S	A predicted alpha-helical domain with a conserved ER motif.
MAG.T21.45_02435	485918.Cpin_5583	6.8e-101	374.0	Sphingobacteriia	MA20_32430												Bacteria	1IPWA@117747,4NF4N@976,COG1305@1,COG1305@2	NA|NA|NA	E	COGs COG1305 Transglutaminase-like protein
MAG.T21.45_02436	1185876.BN8_03199	1.1e-102	379.8	Cytophagia													Bacteria	47NTV@768503,4NEH9@976,COG5285@1,COG5285@2	NA|NA|NA	Q	Phytanoyl-CoA dioxygenase (PhyH)
MAG.T21.45_02437	929562.Emtol_1200	8.4e-197	693.0	Cytophagia													Bacteria	47MAS@768503,4NJ92@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_02438	761193.Runsl_4256	3.2e-282	977.6	Cytophagia													Bacteria	47MUU@768503,4NFQ6@976,COG2091@1,COG2091@2	NA|NA|NA	H	Carbohydrate family 9 binding domain-like
MAG.T21.45_02439	1150600.ADIARSV_1580	1.7e-117	431.0	Sphingobacteriia			4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024		R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000				Bacteria	1ISWY@117747,4NHDQ@976,COG3656@1,COG3656@2,COG4677@1,COG4677@2	NA|NA|NA	G	Fibronectin type 3 domain
MAG.T21.45_02440	1137281.D778_01370	1.1e-24	120.9	Flavobacteriia													Bacteria	1HWKC@117743,4NEVD@976,COG3064@1,COG3064@2	NA|NA|NA	M	membrane
MAG.T21.45_02441	1121286.AUMT01000025_gene2539	2.5e-25	123.2	Bacteria													Bacteria	COG5295@1,COG5295@2	NA|NA|NA	UW	Hep Hag repeat protein
MAG.T21.45_02443	929556.Solca_3541	1.2e-28	133.3	Sphingobacteriia				ko:K03088					ko00000,ko03021				Bacteria	1ISKR@117747,4NKHT@976,COG1595@1,COG1595@2	NA|NA|NA	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family
MAG.T21.45_02444	1121904.ARBP01000018_gene2706	2.1e-157	562.4	Cytophagia				ko:K03307					ko00000	2.A.21			Bacteria	47KPI@768503,4NEN8@976,COG0591@1,COG0591@2	NA|NA|NA	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MAG.T21.45_02445	1048983.EL17_09065	1.3e-64	253.4	Cytophagia			4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000				Bacteria	47TB8@768503,4NFIH@976,COG0329@1,COG0329@2	NA|NA|NA	EM	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MAG.T21.45_02446	761193.Runsl_0088	8.6e-89	334.0	Cytophagia			3.2.1.51	ko:K01206	ko00511,map00511				ko00000,ko00001,ko01000,ko04147		GH29		Bacteria	47JNA@768503,4NEDX@976,COG3669@1,COG3669@2,COG4409@1,COG4409@2,COG4692@1,COG4692@2	NA|NA|NA	G	Coagulation factor 5 8 type domain protein
MAG.T21.45_02447	760192.Halhy_2083	9.4e-42	177.6	Bacteroidetes	mprF			ko:K07027					ko00000,ko02000	4.D.2			Bacteria	4NI8Y@976,COG0392@1,COG0392@2	NA|NA|NA	S	PFAM Uncharacterised protein family (UPF0104)
MAG.T21.45_02448	1122605.KB893643_gene694	1.5e-129	469.9	Sphingobacteriia	nnrD		4.2.1.136,5.1.99.6	ko:K17758,ko:K17759					ko00000,ko01000				Bacteria	1IR01@117747,4NG2F@976,COG0062@1,COG0062@2,COG0063@1,COG0063@2	NA|NA|NA	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MAG.T21.45_02449	929703.KE386491_gene2223	4.8e-114	418.7	Cytophagia			3.2.1.51	ko:K01206	ko00511,map00511				ko00000,ko00001,ko01000,ko04147		GH29		Bacteria	47NVV@768503,4NEJ0@976,COG2010@1,COG2010@2,COG2133@1,COG2133@2	NA|NA|NA	C	Domain of Unknown Function (DUF1080)
MAG.T21.45_02450	760192.Halhy_5136	5.3e-220	770.8	Sphingobacteriia													Bacteria	1IUR8@117747,4NEMM@976,COG2133@1,COG2133@2,COG3241@1,COG3241@2	NA|NA|NA	CG	Copper binding proteins, plastocyanin/azurin family
MAG.T21.45_02451	1168289.AJKI01000053_gene761	9.6e-185	653.3	Bacteroidia													Bacteria	2FMGA@200643,4NF1X@976,COG3119@1,COG3119@2	NA|NA|NA	P	COG COG3119 Arylsulfatase A and related enzymes
MAG.T21.45_02452	1380384.JADN01000003_gene384	4e-30	137.5	Bacteria													Bacteria	COG4270@1,COG4270@2	NA|NA|NA		
MAG.T21.45_02453	78898.MVEG_10657T0	3.5e-72	279.3	Fungi incertae sedis			1.13.11.52	ko:K00463	ko00380,ko01100,ko05143,map00380,map01100,map05143	M00038	R00678,R02702,R02909,R03628	RC00356	ko00000,ko00001,ko00002,ko01000				Fungi	1GSWA@112252,28JZM@1,2QSE1@2759,38I4B@33154,3NUI1@4751	NA|NA|NA	E	Indoleamine 2,3-dioxygenase
MAG.T21.45_02454	1122176.KB903565_gene3249	1.7e-54	219.2	Sphingobacteriia	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1ISJU@117747,4NDV6@976,COG0817@1,COG0817@2	NA|NA|NA	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MAG.T21.45_02455	1237149.C900_03069	6.2e-89	334.0	Cytophagia													Bacteria	47M76@768503,4NGQY@976,COG1028@1,COG1028@2	NA|NA|NA	IQ	KR domain
MAG.T21.45_02456	886379.AEWI01000023_gene19	6.1e-43	180.3	Marinilabiliaceae	hit			ko:K02503					ko00000,ko04147				Bacteria	2FSRY@200643,3XK4J@558415,4NQ4X@976,COG0537@1,COG0537@2	NA|NA|NA	FG	HIT domain
MAG.T21.45_02457	760192.Halhy_3179	2.5e-56	224.9	Sphingobacteriia	greA			ko:K03624					ko00000,ko03021				Bacteria	1IS01@117747,4NNH6@976,COG0782@1,COG0782@2	NA|NA|NA	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MAG.T21.45_02458	760192.Halhy_4035	7.8e-106	390.6	Sphingobacteriia													Bacteria	1IYUI@117747,4NWE8@976,COG2067@1,COG2067@2	NA|NA|NA	I	long-chain fatty acid transport protein
MAG.T21.45_02459	760192.Halhy_4034	0.0	1921.7	Sphingobacteriia													Bacteria	1J03H@117747,2E09V@1,32VXB@2,4NY12@976	NA|NA|NA		
MAG.T21.45_02460	760192.Halhy_4033	0.0	1665.2	Sphingobacteriia													Bacteria	1J0XF@117747,4NTQD@976,COG1629@1,COG4206@1,COG4206@2,COG4771@2	NA|NA|NA	P	Carboxypeptidase regulatory-like domain
MAG.T21.45_02461	313603.FB2170_03995	2.5e-91	342.4	Flavobacteriia			1.14.15.7	ko:K00499	ko00260,map00260		R07409	RC00087	ko00000,ko00001,ko01000				Bacteria	1HZFM@117743,4NJ33@976,COG4638@1,COG4638@2	NA|NA|NA	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit
MAG.T21.45_02462	1122176.KB903548_gene1180	3e-238	831.6	Sphingobacteriia													Bacteria	1IPM9@117747,4NFQ6@976,COG2091@1,COG2091@2	NA|NA|NA	H	Carbohydrate family 9 binding domain-like
MAG.T21.45_02464	760192.Halhy_3025	9.8e-173	614.8	Sphingobacteriia			4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000				Bacteria	1IZ0P@117747,4NUFW@976,COG0457@1,COG0457@2,COG2114@1,COG2114@2,COG3899@1,COG3899@2	NA|NA|NA	T	AAA ATPase domain
MAG.T21.45_02465	760192.Halhy_3299	1.1e-174	619.8	Sphingobacteriia	gatA		6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100		R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029				Bacteria	1IQR9@117747,4NF8C@976,COG0154@1,COG0154@2	NA|NA|NA	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MAG.T21.45_02466	1185876.BN8_04438	4.7e-44	184.5	Cytophagia			1.5.1.38	ko:K00299,ko:K11811	ko00740,ko00920,ko01100,map00740,map00920,map01100		R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000				Bacteria	47PJD@768503,4NMRM@976,COG0431@1,COG0431@2	NA|NA|NA	S	NADPH-dependent FMN reductase
MAG.T21.45_02467	1041826.FCOL_11560	2.1e-96	359.0	Flavobacterium													Bacteria	1IDM6@117743,2NYQW@237,4NJT2@976,COG5464@1,COG5464@2	NA|NA|NA	S	PD-(D/E)XK nuclease family transposase
MAG.T21.45_02468	760192.Halhy_2616	3.2e-54	218.0	Sphingobacteriia	comM			ko:K07391					ko00000				Bacteria	1INNX@117747,4NE0G@976,COG0606@1,COG0606@2	NA|NA|NA	O	chelatase, subunit chli
MAG.T21.45_02470	1144313.PMI10_03773	5.6e-51	208.4	Flavobacterium				ko:K07504					ko00000				Bacteria	1HXGR@117743,2NVKQ@237,4NDZX@976,COG4748@1,COG4748@2	NA|NA|NA	L	Type I restriction enzyme R protein N terminus (HSDR_N)
MAG.T21.45_02473	1492737.FEM08_36480	5.9e-59	234.2	Flavobacteriia													Bacteria	1I1M8@117743,4NK59@976,COG1961@1,COG1961@2	NA|NA|NA	L	Resolvase, N terminal domain
MAG.T21.45_02474	558152.IQ37_06685	3.7e-28	131.7	Chryseobacterium	radC			ko:K03630					ko00000				Bacteria	1HXJ3@117743,3ZQ9M@59732,4NFBF@976,COG2003@1,COG2003@2	NA|NA|NA	E	Belongs to the UPF0758 family
MAG.T21.45_02478	938709.AUSH02000045_gene398	1.8e-232	812.0	Bacteroidetes	hsdM		2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	4NG0E@976,COG0286@1,COG0286@2	NA|NA|NA	V	type I restriction-modification system
MAG.T21.45_02479	880070.Cycma_3431	1.5e-81	309.7	Cytophagia													Bacteria	47VPD@768503,4NERW@976,COG3586@1,COG3586@2	NA|NA|NA	L	endonuclease activity
MAG.T21.45_02480	1123401.JHYQ01000012_gene2822	7.5e-98	364.4	Thiotrichales	hsdS		3.1.21.3	ko:K01154					ko00000,ko01000,ko02048				Bacteria	1Q4FB@1224,1RS7D@1236,4615T@72273,COG0732@1,COG0732@2	NA|NA|NA	V	Type I restriction modification DNA specificity domain
MAG.T21.45_02481	938709.AUSH02000045_gene395	0.0	1127.1	Bacteroidetes	hsdR		3.1.21.3	ko:K01153					ko00000,ko01000,ko02048				Bacteria	4NFJ8@976,COG0610@1,COG0610@2	NA|NA|NA	L	Subunit R is required for both nuclease and ATPase activities, but not for modification
MAG.T21.45_02485	1250278.JQNQ01000001_gene2191	4.5e-15	89.7	Bacteria													Bacteria	COG4974@1,COG4974@2	NA|NA|NA	L	Belongs to the 'phage' integrase family
MAG.T21.45_02486	760192.Halhy_2616	6.9e-153	547.0	Sphingobacteriia	comM			ko:K07391					ko00000				Bacteria	1INNX@117747,4NE0G@976,COG0606@1,COG0606@2	NA|NA|NA	O	chelatase, subunit chli
MAG.T21.45_02487	1131812.JQMS01000001_gene783	3.3e-12	77.8	Flavobacterium													Bacteria	1I425@117743,2C9BK@1,2NWMY@237,32RP1@2,4NSPA@976	NA|NA|NA	S	Domain of unknown function (DUF4286)
MAG.T21.45_02488	760192.Halhy_2630	9.8e-47	193.7	Sphingobacteriia													Bacteria	1IQZH@117747,28H5J@1,2Z7I5@2,4NHK6@976	NA|NA|NA	S	Domain of unknown function (DUF4290)
MAG.T21.45_02489	760192.Halhy_4602	3.1e-88	334.3	Bacteroidetes													Bacteria	4NTMJ@976,COG3210@1,COG3210@2,COG3591@1,COG3591@2	NA|NA|NA	U	Putative binding domain, N-terminal
MAG.T21.45_02490	1122176.KB903540_gene129	3.6e-110	405.2	Sphingobacteriia	lolE			ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255			ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5			Bacteria	1IPJE@117747,4NG04@976,COG4591@1,COG4591@2	NA|NA|NA	M	ABC-type transport system involved in lipoprotein release permease component
MAG.T21.45_02491	641526.ADIWIN_3244	1.1e-62	247.7	Flavobacteriia				ko:K21572					ko00000,ko02000	8.A.46.1,8.A.46.3			Bacteria	1I1IP@117743,4NHC0@976,COG3193@1,COG3193@2	NA|NA|NA	S	SusD family
MAG.T21.45_02492	1356852.N008_13155	2.6e-67	261.9	Cytophagia													Bacteria	47YE9@768503,4P1Z5@976,COG1629@1,COG4771@2	NA|NA|NA	P	PFAM TonB-dependent Receptor Plug Domain
MAG.T21.45_02493	1122176.KB903548_gene1154	3.3e-15	88.6	Bacteroidetes													Bacteria	2E7JF@1,3321M@2,4NWMH@976	NA|NA|NA		
MAG.T21.45_02494	760192.Halhy_2636	0.0	1109.7	Sphingobacteriia	parC	GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363	5.99.1.3	ko:K02469,ko:K02621					ko00000,ko01000,ko02048,ko03032,ko03036,ko03400				Bacteria	1IQ9E@117747,4NERI@976,COG0188@1,COG0188@2	NA|NA|NA	L	COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit
MAG.T21.45_02495	760192.Halhy_0934	6.4e-178	631.3	Sphingobacteriia													Bacteria	1IP87@117747,4NEE5@976,COG4485@1,COG4485@2	NA|NA|NA	S	Bacterial membrane protein YfhO
MAG.T21.45_02496	886377.Murru_0564	5.1e-95	354.8	Flavobacteriia	galK		2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1HWZC@117743,4NE0C@976,COG0153@1,COG0153@2	NA|NA|NA	G	Belongs to the GHMP kinase family. GalK subfamily
MAG.T21.45_02497	760192.Halhy_2838	2.1e-263	915.2	Sphingobacteriia	pheT	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iG2583_1286.G2583_2160,iPC815.YPO2428	Bacteria	1IPW0@117747,4NF5B@976,COG0072@1,COG0072@2,COG0073@1,COG0073@2	NA|NA|NA	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MAG.T21.45_02498	760192.Halhy_2841	7.2e-194	683.7	Sphingobacteriia	rny			ko:K05802,ko:K18682	ko03018,map03018				ko00000,ko00001,ko01000,ko02000,ko03019	1.A.23.1.1			Bacteria	1IQZ1@117747,4NE3V@976,COG1418@1,COG1418@2,COG4372@1,COG4372@2	NA|NA|NA	M	Endoribonuclease that initiates mRNA decay
MAG.T21.45_02499	760192.Halhy_4737	2.2e-39	169.1	Sphingobacteriia													Bacteria	1IS8E@117747,4NNM9@976,COG4636@1,COG4636@2	NA|NA|NA	S	Putative restriction endonuclease
MAG.T21.45_02500	760192.Halhy_4737	3e-41	175.3	Sphingobacteriia													Bacteria	1IS8E@117747,4NNM9@976,COG4636@1,COG4636@2	NA|NA|NA	S	Putative restriction endonuclease
MAG.T21.45_02501	760192.Halhy_4737	9.5e-40	170.2	Sphingobacteriia													Bacteria	1IS8E@117747,4NNM9@976,COG4636@1,COG4636@2	NA|NA|NA	S	Putative restriction endonuclease
MAG.T21.45_02502	1150864.MILUP08_46842	8.3e-48	198.0	Micromonosporales													Bacteria	2I4VD@201174,4DHGI@85008,COG2247@1,COG2247@2,COG4733@1,COG4733@2	NA|NA|NA	M	Fibronectin type 3 domain
MAG.T21.45_02503	509635.N824_14475	6.3e-80	304.7	Bacteroidetes													Bacteria	28HEJ@1,2Z7QZ@2,4NV7J@976	NA|NA|NA		
MAG.T21.45_02504	485917.Phep_0758	1.4e-33	150.2	Bacteroidetes													Bacteria	2ES5Y@1,33JQQ@2,4NYMK@976	NA|NA|NA		
MAG.T21.45_02505	688270.Celal_0757	4e-164	585.9	Cellulophaga													Bacteria	1FA4R@104264,1HX4C@117743,4NEE8@976,COG4888@1,COG4888@2	NA|NA|NA	S	PFAM ASPIC and UnbV
MAG.T21.45_02506	700598.Niako_0532	4.7e-260	904.0	Sphingobacteriia													Bacteria	1IRB7@117747,4NDYB@976,COG3537@1,COG3537@2	NA|NA|NA	G	PFAM Glycosyl hydrolase family 92
MAG.T21.45_02507	1121481.AUAS01000016_gene2629	7.7e-138	497.3	Cytophagia	araE	GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600		ko:K02100					ko00000,ko02000	2.A.1.1.2			Bacteria	47MBV@768503,4NE09@976,COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
MAG.T21.45_02508	1121101.HMPREF1532_02879	9.1e-184	650.2	Bacteroidaceae													Bacteria	2FNY1@200643,4AMYT@815,4NF9A@976,COG1482@1,COG1482@2	NA|NA|NA	G	Psort location Cytoplasmic, score 8.96
MAG.T21.45_02509	1121481.AUAS01000016_gene2628	7.1e-66	257.7	Cytophagia			2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	47TDB@768503,4NKSF@976,COG1940@1,COG1940@2	NA|NA|NA	GK	ROK family
MAG.T21.45_02510	485917.Phep_0755	1e-138	500.4	Sphingobacteriia			1.14.14.47	ko:K00491,ko:K21572	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110		R11711,R11712,R11713	RC00177,RC00330,RC01044	ko00000,ko00001,ko01000,ko02000	8.A.46.1,8.A.46.3			Bacteria	1INZ5@117747,4NEDB@976,COG0702@1,COG0702@2	NA|NA|NA	GM	PFAM RagB SusD
MAG.T21.45_02511	485917.Phep_0754	5.1e-270	937.6	Sphingobacteriia													Bacteria	1J0JI@117747,4NDXS@976,COG1629@1,COG1629@2	NA|NA|NA	P	TonB dependent receptor
MAG.T21.45_02512	869213.JCM21142_173	8.2e-54	217.2	Cytophagia	yvoA			ko:K03710					ko00000,ko03000				Bacteria	47P7I@768503,4NFVY@976,COG2188@1,COG2188@2	NA|NA|NA	K	UTRA
MAG.T21.45_02513	485917.Phep_0760	2.6e-150	539.3	Sphingobacteriia			3.1.1.53	ko:K05970					ko00000,ko01000				Bacteria	1IP3A@117747,4NEDP@976,COG3250@1,COG3250@2	NA|NA|NA	G	Glycosyl hydrolases family 2, sugar binding domain
MAG.T21.45_02514	1279009.ADICEAN_03908	1.1e-98	367.1	Bacteria													Bacteria	28HEJ@1,2Z7QZ@2	NA|NA|NA		
MAG.T21.45_02515	1338011.BD94_3165	5.5e-54	217.2	Elizabethkingia													Bacteria	1IG1T@117743,34S70@308865,4NE0Q@976,COG4804@1,COG4804@2	NA|NA|NA	S	Protein of unknown function (DUF1016)
MAG.T21.45_02516	471853.Bcav_1414	3.2e-54	218.8	Bacteria			3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	COG3386@1,COG3386@2	NA|NA|NA	G	gluconolactonase activity
MAG.T21.45_02517	411902.CLOBOL_02418	5.7e-53	214.9	Lachnoclostridium													Bacteria	1UEJW@1239,222S6@1506553,25JI2@186801,COG2017@1,COG2017@2	NA|NA|NA	G	Domain of unknown function (DUF4432)
MAG.T21.45_02518	313603.FB2170_03875	1.2e-109	403.3	Maribacter	uxuA		4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000				Bacteria	1HWT6@117743,2PHWZ@252356,4NF30@976,COG1312@1,COG1312@2	NA|NA|NA	G	D-mannonate dehydratase (UxuA)
MAG.T21.45_02519	1123073.KB899241_gene3102	2.3e-62	245.7	Gammaproteobacteria													Bacteria	1MVQW@1224,1RNY1@1236,COG1028@1,COG1028@2	NA|NA|NA	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MAG.T21.45_02520	1346330.M472_08380	1.2e-172	612.8	Bacteroidetes				ko:K06921					ko00000				Bacteria	4NJ2E@976,COG1672@1,COG1672@2	NA|NA|NA	S	ATPase (AAA superfamily)
MAG.T21.45_02521	714943.Mucpa_0897	2.5e-205	721.5	Sphingobacteriia				ko:K07133					ko00000				Bacteria	1IUTK@117747,4NHQG@976,COG1373@1,COG1373@2	NA|NA|NA	S	Domain of unknown function (DUF4143)
MAG.T21.45_02522	1197477.IA57_07555	9.5e-42	176.0	Flavobacteriia				ko:K07133					ko00000				Bacteria	1HYK8@117743,4NE3E@976,COG1373@1,COG1373@2	NA|NA|NA	S	AAA domain
MAG.T21.45_02523	313595.P700755_001654	1e-87	329.7	Flavobacteriia				ko:K07133					ko00000				Bacteria	1HYK8@117743,4NE3E@976,COG1373@1,COG1373@2	NA|NA|NA	S	AAA domain
MAG.T21.45_02524	1121481.AUAS01000001_gene4461	1.8e-138	499.2	Cytophagia													Bacteria	47Y7M@768503,4PKVJ@976,COG3458@1,COG3458@2	NA|NA|NA	Q	Acetyl xylan esterase (AXE1)
MAG.T21.45_02525	365044.Pnap_3123	1.5e-82	312.8	Comamonadaceae	hisF2			ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000				Bacteria	1MUS0@1224,2VHY0@28216,4AA0X@80864,COG0107@1,COG0107@2	NA|NA|NA	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MAG.T21.45_02526	1408312.JNJS01000002_gene4	4.8e-47	194.5	Pseudobutyrivibrio	hisH			ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQT0@1239,248SH@186801,3NHJD@46205,COG0118@1,COG0118@2	NA|NA|NA	E	SNO glutamine amidotransferase family
MAG.T21.45_02527	365044.Pnap_3122	2.2e-119	435.6	Betaproteobacteria	tilS		6.3.4.19	ko:K04075,ko:K14058			R09597	RC02633,RC02634	ko00000,ko01000,ko03016				Bacteria	1NKHX@1224,2VJ4Q@28216,COG0037@1,COG0037@2	NA|NA|NA	D	ATPase of the PP-loop superfamily implicated in cell cycle control
MAG.T21.45_02528	469381.Dpep_0789	2.9e-77	295.8	Bacteria													Bacteria	COG0438@1,COG0438@2	NA|NA|NA	M	transferase activity, transferring glycosyl groups
MAG.T21.45_02529	1268239.PALB_11590	3.6e-154	552.0	Pseudoalteromonadaceae			6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110		R00578	RC00010	ko00000,ko00001,ko01000,ko01002				Bacteria	1MW4E@1224,1RQ7D@1236,2Q2EA@267888,COG0367@1,COG0367@2	NA|NA|NA	E	asparagine synthase (glutamine-hydrolyzing)
MAG.T21.45_02530	856793.MICA_1025	2.4e-55	223.0	unclassified Alphaproteobacteria													Bacteria	1MYJ6@1224,2UMC7@28211,4BSR6@82117,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferase group 1
MAG.T21.45_02531	335284.Pcryo_0622	2.2e-159	569.3	Gammaproteobacteria			6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110		R00578	RC00010	ko00000,ko00001,ko01000,ko01002				Bacteria	1MW4E@1224,1RQ7D@1236,COG0367@1,COG0367@2	NA|NA|NA	E	asparagine synthase, glutamine-hydrolyzing
MAG.T21.45_02532	1174528.JH992898_gene4055	2.1e-16	93.6	Stigonemataceae			2.4.1.60	ko:K13005					ko00000,ko01000,ko01003,ko01005				Bacteria	1GD6J@1117,1JH69@1189,COG0463@1,COG0463@2	NA|NA|NA	M	Glycosyltransferase like family 2
MAG.T21.45_02533	1131812.JQMS01000001_gene284	5.7e-223	780.0	Flavobacterium	rfbH		1.17.1.1,4.2.1.164	ko:K12452,ko:K13328	ko00520,ko00523,ko01130,map00520,map00523,map01130	M00802	R03391,R03392,R08930	RC00230,RC00704	ko00000,ko00001,ko00002,ko01000				Bacteria	1HZDU@117743,2NTSW@237,4NG9W@976,COG0399@1,COG0399@2	NA|NA|NA	E	DegT/DnrJ/EryC1/StrS aminotransferase family
MAG.T21.45_02534	388467.A19Y_0927	1.6e-73	283.1	Bacteria	XK27_03530												Bacteria	COG2520@1,COG2520@2	NA|NA|NA	J	tRNA (guanine(37)-N(1))-methyltransferase activity
MAG.T21.45_02535	1270193.JARP01000003_gene1926	8.6e-137	493.4	Bacteroidetes			4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000				Bacteria	4NHAK@976,COG0451@1,COG0451@2	NA|NA|NA	M	NAD dependent epimerase dehydratase family
MAG.T21.45_02536	1270193.JARP01000003_gene1925	5.5e-157	560.5	Flavobacteriia	mhpE		4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000				Bacteria	1HZQE@117743,4NHR2@976,COG0119@1,COG0119@2	NA|NA|NA	E	HMGL-like
MAG.T21.45_02537	1270193.JARP01000003_gene1924	7.8e-136	490.0	Bacteroidetes	mhpF	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008774,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.10	ko:K04073	ko00360,ko00362,ko00620,ko00621,ko00622,ko00650,ko01100,ko01120,ko01220,map00360,map00362,map00620,map00621,map00622,map00650,map01100,map01120,map01220	M00545,M00569	R00228,R01172	RC00004,RC00184,RC01195	br01602,ko00000,ko00001,ko00002,ko01000				Bacteria	4P2FQ@976,COG4569@1,COG4569@2	NA|NA|NA	Q	Prokaryotic acetaldehyde dehydrogenase, dimerisation
MAG.T21.45_02538	1198452.Jab_2c35020	1.4e-209	736.1	Oxalobacteraceae	ilvB2		2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000				Bacteria	1MU6U@1224,2VJ55@28216,472GV@75682,COG0028@1,COG0028@2	NA|NA|NA	H	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
MAG.T21.45_02539	388467.A19Y_0928	1.5e-112	412.9	Oscillatoriales			4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000				Bacteria	1G3VX@1117,1HE17@1150,COG0451@1,COG0451@2	NA|NA|NA	GM	3-beta hydroxysteroid dehydrogenase/isomerase family
MAG.T21.45_02540	1131812.JQMS01000001_gene287	1.2e-157	562.8	Flavobacterium	rfbG		4.2.1.45	ko:K01709	ko00520,map00520		R02426	RC00402	ko00000,ko00001,ko01000				Bacteria	1I7V2@117743,2NUN1@237,4NFHJ@976,COG0451@1,COG0451@2	NA|NA|NA	M	Polysaccharide biosynthesis protein
MAG.T21.45_02541	1270193.JARP01000003_gene1919	4.4e-130	470.7	Flavobacterium	rfbF		2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100		R00956	RC00002	ko00000,ko00001,ko01000				Bacteria	1ING9@117743,2NUY1@237,4NG3V@976,COG1208@1,COG1208@2	NA|NA|NA	JM	MobA-like NTP transferase domain
MAG.T21.45_02542	1131812.JQMS01000001_gene289	1.1e-96	360.1	Flavobacterium	paaE			ko:K02613	ko00360,ko01120,map00360,map01120		R09838	RC02690	ko00000,ko00001				Bacteria	1IG1V@117743,2NVJW@237,4NF24@976,COG1018@1,COG1018@2	NA|NA|NA	C	Oxidoreductase FAD-binding domain
MAG.T21.45_02543	395494.Galf_2843	4.6e-167	594.7	Betaproteobacteria	pglK	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0008643,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015772,GO:0015920,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0022804,GO:0022857,GO:0022884,GO:0033036,GO:0034040,GO:0034645,GO:0036211,GO:0042623,GO:0042626,GO:0043170,GO:0043412,GO:0043413,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0051179,GO:0051234,GO:0055085,GO:0070085,GO:0071702,GO:0071704,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576		ko:K06147,ko:K06148					ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	1MVJD@1224,2VMV8@28216,COG1132@1,COG1132@2	NA|NA|NA	V	Pfam ABC transporter
MAG.T21.45_02544	925409.KI911562_gene155	9.9e-57	226.5	Sphingobacteriia				ko:K07075					ko00000				Bacteria	1IT8B@117747,4NS23@976,COG0640@1,COG0640@2	NA|NA|NA	K	Transcriptional regulator
MAG.T21.45_02545	1189612.A33Q_0326	2.9e-54	218.0	Bacteroidetes				ko:K07133					ko00000				Bacteria	4NED3@976,COG1373@1,COG1373@2	NA|NA|NA	S	ATPase (AAA superfamily)
MAG.T21.45_02546	1121896.JMLU01000029_gene2957	6.3e-34	150.2	Flavobacterium				ko:K07133					ko00000				Bacteria	1HZVJ@117743,2NZWT@237,4NED3@976,COG1373@1,COG1373@2	NA|NA|NA	S	AAA domain
MAG.T21.45_02547	1189619.pgond44_14748	3.4e-17	94.0	Psychroflexus				ko:K07133					ko00000				Bacteria	1HZVJ@117743,4C45N@83612,4NED3@976,COG1373@1,COG1373@2	NA|NA|NA	S	AAA domain
MAG.T21.45_02548	385682.AFSL01000048_gene512	3.5e-17	94.4	Bacteroidia													Bacteria	2FSGR@200643,4NPW4@976,COG2253@1,COG2253@2	NA|NA|NA	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system
MAG.T21.45_02549	866536.Belba_2371	4.6e-19	100.5	Cytophagia													Bacteria	47RNQ@768503,4NUAF@976,COG2253@1,COG2253@2	NA|NA|NA	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system
MAG.T21.45_02550	1122931.AUAE01000031_gene2909	4.1e-18	97.4	Bacteroidia													Bacteria	2DPBF@1,2FU2U@200643,331D6@2,4NV6I@976	NA|NA|NA		
MAG.T21.45_02551	533240.CRC_00318	8.2e-120	437.2	Cyanobacteria													Bacteria	1GC3Q@1117,COG1672@1,COG1672@2	NA|NA|NA	S	PD-(D/E)XK nuclease superfamily
MAG.T21.45_02552	385682.AFSL01000048_gene511	5.1e-09	66.6	Marinilabiliaceae													Bacteria	2DPBF@1,2FU2U@200643,331D6@2,3XKXT@558415,4NV6I@976	NA|NA|NA		
MAG.T21.45_02553	768671.ThimaDRAFT_0480	7.3e-48	196.8	Chromatiales													Bacteria	1NBPF@1224,1S7DZ@1236,1WZDT@135613,2C4WJ@1,32Z4K@2	NA|NA|NA		
MAG.T21.45_02554	768671.ThimaDRAFT_0481	3.8e-27	127.5	Chromatiales													Bacteria	1N7SN@1224,1SGAJ@1236,1X2N1@135613,COG1708@1,COG1708@2	NA|NA|NA	L	PFAM DNA polymerase, beta domain protein region
MAG.T21.45_02555	1269813.ATUL01000002_gene972	5.7e-27	126.7	Gammaproteobacteria				ko:K07076					ko00000				Bacteria	1N9QY@1224,1SE01@1236,COG1708@1,COG1708@2	NA|NA|NA	S	Nucleotidyltransferase domain
MAG.T21.45_02557	760192.Halhy_4443	7.9e-147	527.3	Bacteroidetes													Bacteria	4NIJ4@976,COG1672@1,COG1672@2	NA|NA|NA	S	Psort location Cytoplasmic, score 8.96
MAG.T21.45_02558	1124780.ANNU01000005_gene2421	6.7e-133	480.3	Cytophagia	wbpB		1.1.1.335	ko:K13016	ko00520,map00520		R10140	RC00182	ko00000,ko00001,ko01000,ko01005				Bacteria	47KDG@768503,4PITU@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, C-terminal alpha/beta domain
MAG.T21.45_02559	1250005.PHEL85_1550	2.9e-54	218.4	Polaribacter	cysG		1.3.1.76,4.99.1.4	ko:K02304,ko:K07090	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000				Bacteria	1HYI1@117743,3VVM4@52959,4NI81@976,COG1648@1,COG1648@2	NA|NA|NA	H	Sirohaem biosynthesis protein central
MAG.T21.45_02560	388413.ALPR1_01570	5.8e-58	231.1	Cytophagia	cobA		1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000				Bacteria	47JQG@768503,4NFVR@976,COG0007@1,COG0007@2	NA|NA|NA	H	TIGRFAM Uroporphyrin-III C-methyltransferase
MAG.T21.45_02561	1122176.KB903587_gene4367	1.2e-222	779.6	Sphingobacteriia	cysI		1.7.1.15,1.7.7.1,1.8.1.2,1.8.7.1	ko:K00362,ko:K00366,ko:K00381,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00530,M00531	R00787,R00790,R00858,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000				Bacteria	1INY4@117747,4NENW@976,COG0155@1,COG0155@2	NA|NA|NA	C	Nitrite and sulphite reductase 4Fe-4S
MAG.T21.45_02562	926549.KI421517_gene1257	1.6e-111	411.0	Cytophagia				ko:K07004					ko00000				Bacteria	47M74@768503,4NHFV@976,COG2374@1,COG2374@2,COG4932@1,COG4932@2	NA|NA|NA	M	endonuclease I
MAG.T21.45_02563	929703.KE386491_gene140	3.3e-126	458.0	Cytophagia	fieF												Bacteria	47MS6@768503,4NEID@976,COG0053@1,COG0053@2	NA|NA|NA	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MAG.T21.45_02564	760192.Halhy_4737	6.5e-57	227.3	Sphingobacteriia													Bacteria	1IS8E@117747,4NNM9@976,COG4636@1,COG4636@2	NA|NA|NA	S	Putative restriction endonuclease
MAG.T21.45_02565	760192.Halhy_4737	2.5e-56	225.3	Sphingobacteriia													Bacteria	1IS8E@117747,4NNM9@976,COG4636@1,COG4636@2	NA|NA|NA	S	Putative restriction endonuclease
MAG.T21.45_02566	926556.Echvi_4613	2e-12	77.8	Cytophagia													Bacteria	47S1D@768503,4NXSU@976,COG4877@1,COG4877@2	NA|NA|NA		
MAG.T21.45_02567	1123037.AUDE01000019_gene3237	5e-77	294.7	Flavobacteriia	f42a												Bacteria	1HZ2R@117743,4NEBV@976,COG0330@1,COG0330@2	NA|NA|NA	O	Membrane protease subunits, stomatin prohibitin homologs
MAG.T21.45_02568	1317122.ATO12_21640	1.2e-33	149.1	Aquimarina													Bacteria	1I3Q8@117743,2YJVC@290174,4NRR5@976,COG1917@1,COG1917@2	NA|NA|NA	S	Cupin domain
MAG.T21.45_02569	1121875.KB907547_gene3492	8e-93	347.4	Flavobacteriia													Bacteria	1HZV3@117743,4NH8T@976,COG4299@1,COG4299@2	NA|NA|NA	S	Domain of unknown function (DUF5009)
MAG.T21.45_02571	760192.Halhy_2988	1.1e-136	494.2	Sphingobacteriia													Bacteria	1IQSN@117747,4NEV1@976,COG1916@1,COG1916@2	NA|NA|NA		
MAG.T21.45_02572	1122176.KB903542_gene338	4.4e-128	464.5	Sphingobacteriia	yehL												Bacteria	1IRHM@117747,4NI8D@976,COG0714@1,COG0714@2	NA|NA|NA	S	PFAM ATPase associated with various cellular activities
MAG.T21.45_02573	760192.Halhy_2775	5.9e-51	207.2	Sphingobacteriia				ko:K09950					ko00000				Bacteria	1J0DJ@117747,4NTUM@976,COG3495@1,COG3495@2	NA|NA|NA	S	Protein conserved in bacteria
MAG.T21.45_02574	760192.Halhy_3661	1.4e-126	459.9	Sphingobacteriia				ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1J0VQ@117747,4NF60@976,COG0577@1,COG0577@2	NA|NA|NA	V	FtsX-like permease family
MAG.T21.45_02575	760192.Halhy_3662	1.1e-57	229.9	Sphingobacteriia				ko:K02003		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1J088@117747,4NNS2@976,COG1136@1,COG1136@2	NA|NA|NA	V	AAA domain, putative AbiEii toxin, Type IV TA system
MAG.T21.45_02577	1250278.JQNQ01000001_gene3352	5.8e-207	727.2	Flavobacteriia	ggt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100		R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002			iAPECO1_1312.APECO1_3012,iECOK1_1307.ECOK1_3869,iECS88_1305.ECS88_3844,iECW_1372.ECW_m3706,iEKO11_1354.EKO11_0296,iETEC_1333.ETEC_3693,iUMN146_1321.UM146_17325,iUTI89_1310.UTI89_C3954,iWFL_1372.ECW_m3706	Bacteria	1HXTC@117743,4NF2H@976,COG0405@1,COG0405@2	NA|NA|NA	E	gamma-glutamyltranspeptidase
MAG.T21.45_02578	309799.DICTH_0359	1.4e-90	340.1	Bacteria	bglA		3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110		R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000				Bacteria	COG2723@1,COG2723@2	NA|NA|NA	G	beta-glucosidase activity
MAG.T21.45_02580	1122176.KB903532_gene2745	4.2e-23	114.8	Sphingobacteriia				ko:K13993	ko04141,map04141				ko00000,ko00001,ko03110				Bacteria	1IT7T@117747,4NQXY@976,COG0071@1,COG0071@2	NA|NA|NA	O	Belongs to the small heat shock protein (HSP20) family
MAG.T21.45_02581	760192.Halhy_2845	2.5e-48	199.5	Bacteria				ko:K02660	ko02020,ko02025,map02020,map02025				ko00000,ko00001,ko02035,ko02044				Bacteria	COG1858@1,COG1858@2	NA|NA|NA	C	electron transfer activity
MAG.T21.45_02582	468059.AUHA01000002_gene1339	2.8e-239	835.1	Sphingobacteriia													Bacteria	1IRKN@117747,4NE60@976,COG1506@1,COG1506@2	NA|NA|NA	E	Prolyl oligopeptidase family
MAG.T21.45_02583	760192.Halhy_3358	0.0	1338.2	Sphingobacteriia	clpB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030312,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0040007,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564		ko:K03694,ko:K03695	ko04213,map04213				ko00000,ko00001,ko03110				Bacteria	1IQP6@117747,4NGEM@976,COG0542@1,COG0542@2	NA|NA|NA	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MAG.T21.45_02584	925409.KI911562_gene2266	2.9e-76	292.0	Bacteroidetes													Bacteria	4NJ5I@976,COG2227@1,COG2227@2	NA|NA|NA	H	Methyltransferase domain
MAG.T21.45_02585	1122176.KB903565_gene3219	2.1e-59	236.1	Sphingobacteriia	gppA-2		3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230		R03409	RC00002	ko00000,ko00001,ko01000				Bacteria	1IQTS@117747,4NH03@976,COG0248@1,COG0248@2	NA|NA|NA	FP	PFAM Ppx GppA phosphatase
MAG.T21.45_02586	760192.Halhy_4131	3.6e-174	617.8	Sphingobacteriia	glgC		2.7.7.27,3.2.1.68	ko:K00975,ko:K01214	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948,R09995,R11261	RC00002	ko00000,ko00001,ko00002,ko01000		CBM48,GH13	iJN678.agp,iSbBS512_1146.agp	Bacteria	1IP6Q@117747,4NDVJ@976,COG0448@1,COG0448@2	NA|NA|NA	G	glucose-1-phosphate adenylyltransferase
MAG.T21.45_02587	760192.Halhy_4132	7.1e-158	563.9	Sphingobacteriia	glgA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003		GT5		Bacteria	1IQCB@117747,4NET6@976,COG0297@1,COG0297@2	NA|NA|NA	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose
MAG.T21.45_02589	760192.Halhy_1705	8.9e-212	743.0	Sphingobacteriia													Bacteria	1J0MB@117747,4NDYR@976,COG0318@1,COG0318@2	NA|NA|NA	IQ	PFAM GH3 auxin-responsive promoter
MAG.T21.45_02590	760192.Halhy_1704	6.6e-53	214.2	Sphingobacteriia	ydcC												Bacteria	1ISAH@117747,4NFGN@976,COG2834@1,COG2834@2	NA|NA|NA	M	PFAM Outer membrane lipoprotein carrier protein LolA
MAG.T21.45_02591	929562.Emtol_1098	6.6e-78	297.7	Cytophagia				ko:K02529					ko00000,ko03000				Bacteria	47MGC@768503,4NDW6@976,COG1609@1,COG1609@2	NA|NA|NA	K	PFAM Periplasmic binding protein LacI transcriptional regulator
MAG.T21.45_02592	1005048.CFU_0231	1.3e-21	109.4	Oxalobacteraceae	MA20_44825												Bacteria	1NCJR@1224,2VURJ@28216,477EQ@75682,COG4319@1,COG4319@2	NA|NA|NA	S	Domain of unknown function (DUF4440)
MAG.T21.45_02593	714943.Mucpa_3661	1.2e-109	403.7	Sphingobacteriia	uxaB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009026,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	1.1.1.17,1.1.1.58	ko:K00009,ko:K00041	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00631	R02555,R02703	RC00085	ko00000,ko00001,ko00002,ko01000			iECABU_c1320.ECABU_c17480	Bacteria	1INT3@117747,4NEMT@976,COG0246@1,COG0246@2	NA|NA|NA	G	Mannitol dehydrogenase domain protein
MAG.T21.45_02595	760192.Halhy_3408	2.4e-41	175.6	Sphingobacteriia	nusG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141		ko:K02601,ko:K05785					ko00000,ko03000,ko03009,ko03021				Bacteria	1ITZ8@117747,4NSVU@976,COG0250@1,COG0250@2	NA|NA|NA	K	Transcription termination factor nusG
MAG.T21.45_02596	525257.HMPREF0204_12129	2e-55	222.2	Chryseobacterium	wbpD		2.3.1.201	ko:K13018	ko00520,map00520		R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005				Bacteria	1HZ0I@117743,3ZS2S@59732,4NENC@976,COG0110@1,COG0110@2	NA|NA|NA	S	Hexapeptide repeat of succinyl-transferase
MAG.T21.45_02597	760192.Halhy_3409	1.9e-134	485.7	Sphingobacteriia	degT												Bacteria	1IQH3@117747,4NEBI@976,COG0399@1,COG0399@2	NA|NA|NA	E	Belongs to the DegT DnrJ EryC1 family
MAG.T21.45_02598	760192.Halhy_3410	8e-155	553.5	Sphingobacteriia	lhgO		1.1.99.2	ko:K00109,ko:K15736	ko00650,map00650		R03534	RC00031	ko00000,ko00001,ko01000				Bacteria	1IQ3I@117747,4NE0B@976,COG0579@1,COG0579@2	NA|NA|NA	S	FAD dependent oxidoreductase
MAG.T21.45_02599	1122176.KB903546_gene1006	5.6e-86	324.3	Sphingobacteriia	nadC	GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_1988	Bacteria	1INNF@117747,4NDXF@976,COG0157@1,COG0157@2	NA|NA|NA	H	Belongs to the NadC ModD family
MAG.T21.45_02600	760192.Halhy_2930	2.3e-94	352.4	Sphingobacteriia	gldB												Bacteria	1IPUT@117747,4NFZP@976,COG5504@1,COG5504@2	NA|NA|NA	O	Gliding motility protein, GldB
MAG.T21.45_02601	760192.Halhy_2931	4.8e-120	437.6	Sphingobacteriia													Bacteria	1IR2B@117747,4NED5@976,COG3491@1,COG3491@2	NA|NA|NA	C	Belongs to the iron ascorbate-dependent oxidoreductase family
MAG.T21.45_02602	1434325.AZQN01000005_gene3558	2e-297	1028.1	Cytophagia			3.4.14.5	ko:K01278	ko04974,map04974				ko00000,ko00001,ko01000,ko01002,ko04090,ko04147				Bacteria	47KF8@768503,4NETS@976,COG0823@1,COG0823@2,COG1506@1,COG1506@2	NA|NA|NA	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region
MAG.T21.45_02603	760192.Halhy_6405	4.5e-128	464.9	Sphingobacteriia				ko:K03294					ko00000	2.A.3.2			Bacteria	1IRQU@117747,4NJPZ@976,COG0531@1,COG0531@2	NA|NA|NA	E	Amino acid permease
MAG.T21.45_02604	1122176.KB903546_gene976	1.7e-102	379.0	Sphingobacteriia	xth		3.1.11.2	ko:K01142	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1INQC@117747,4NEY3@976,COG0708@1,COG0708@2	NA|NA|NA	L	exodeoxyribonuclease III
MAG.T21.45_02605	1122176.KB903542_gene363	7.1e-44	184.5	Bacteroidetes													Bacteria	2AZ5E@1,31RC3@2,4NYUC@976	NA|NA|NA	S	Outer membrane protein beta-barrel domain
MAG.T21.45_02606	760192.Halhy_2600	1.8e-94	353.6	Sphingobacteriia				ko:K07278					ko00000,ko02000	1.B.33.2.4			Bacteria	1IS7K@117747,4PKYQ@976,COG0729@1,COG0729@2	NA|NA|NA	M	Surface antigen
MAG.T21.45_02607	1122179.KB890417_gene3224	2.9e-310	1071.2	Sphingobacteriia	dnaE-2		2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1IQSQ@117747,4NE2R@976,COG0587@1,COG0587@2	NA|NA|NA	L	DNA polymerase
MAG.T21.45_02608	760192.Halhy_3838	5e-30	137.5	Bacteroidetes													Bacteria	2E5FG@1,33075@2,4NWB7@976	NA|NA|NA		
MAG.T21.45_02609	1123248.KB893315_gene3186	4.3e-88	331.6	Sphingobacteriia	murB		1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100		R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011				Bacteria	1IQP9@117747,4NE78@976,COG0812@1,COG0812@2	NA|NA|NA	M	Cell wall formation
MAG.T21.45_02610	1123248.KB893348_gene228	1.3e-174	619.4	Sphingobacteriia	murA		2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100		R00660	RC00350	ko00000,ko00001,ko01000,ko01011				Bacteria	1IPZR@117747,4NDV8@976,COG0766@1,COG0766@2	NA|NA|NA	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MAG.T21.45_02611	760192.Halhy_1732	4.4e-12	77.4	Bacteroidetes													Bacteria	2EF83@1,33912@2,4NWNU@976	NA|NA|NA	S	Cysteine-rich CWC
MAG.T21.45_02612	760192.Halhy_0386	3.5e-80	305.4	Sphingobacteriia	glxK		2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130		R08572	RC00002,RC00428	ko00000,ko00001,ko01000				Bacteria	1IS9Q@117747,4NFK8@976,COG1929@1,COG1929@2	NA|NA|NA	G	Belongs to the glycerate kinase type-1 family
MAG.T21.45_02613	760192.Halhy_2313	1.9e-220	771.9	Sphingobacteriia				ko:K03308					ko00000	2.A.22.4,2.A.22.5			Bacteria	1IY88@117747,4NGQ5@976,COG0733@1,COG0733@2	NA|NA|NA	S	Sodium:neurotransmitter symporter family
MAG.T21.45_02614	1121897.AUGO01000005_gene113	5.4e-25	122.1	Flavobacterium													Bacteria	1HX17@117743,2NUI0@237,4NGQH@976,COG4198@1,COG4198@2	NA|NA|NA	S	Protein of unknown function (DUF1015)
MAG.T21.45_02615	760192.Halhy_2406	2.1e-115	422.5	Sphingobacteriia	ssnA		3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110		R10695	RC00477	ko00000,ko00001,ko01000				Bacteria	1IPAQ@117747,4NJVU@976,COG0402@1,COG0402@2	NA|NA|NA	F	amidohydrolase
MAG.T21.45_02616	760192.Halhy_1970	1.9e-110	406.4	Sphingobacteriia													Bacteria	1IUAN@117747,4PM54@976,COG1073@1,COG1073@2	NA|NA|NA	S	alpha beta
MAG.T21.45_02617	547042.BACCOPRO_02460	1.2e-68	266.9	Bacteroidaceae													Bacteria	2FKZ2@200643,4AKGA@815,4NFN6@976,COG2755@1,COG2755@2	NA|NA|NA	E	GSCFA family
MAG.T21.45_02618	1349785.BAUG01000040_gene2121	1.2e-82	313.5	Flavobacteriia	argK	GO:0003674,GO:0003824,GO:0003924,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111		ko:K07588					ko00000,ko01000				Bacteria	1HWNS@117743,4NE7Y@976,COG1703@1,COG1703@2	NA|NA|NA	E	periplasmic protein kinase ArgK and related
MAG.T21.45_02619	760192.Halhy_2426	5.6e-77	293.9	Sphingobacteriia	lemA			ko:K03744					ko00000				Bacteria	1IS2G@117747,4NMD3@976,COG1704@1,COG1704@2	NA|NA|NA	S	LemA family
MAG.T21.45_02620	376686.Fjoh_1890	2.9e-30	138.3	Flavobacterium	Z012_08985			ko:K08988					ko00000				Bacteria	1I266@117743,2NW09@237,4NQIT@976,COG3762@1,COG3762@2	NA|NA|NA	S	TPM domain
MAG.T21.45_02621	760192.Halhy_2428	3.4e-34	152.1	Sphingobacteriia	Z012_08980		3.4.24.3	ko:K01387,ko:K06872					ko00000,ko01000,ko01002,ko02042				Bacteria	1IQMF@117747,4NF4P@976,COG1512@1,COG1512@2	NA|NA|NA	S	COG1512 Beta-propeller domains of methanol dehydrogenase type
MAG.T21.45_02622	1453505.JASY01000007_gene1031	7e-60	237.3	Flavobacterium													Bacteria	1IJ7F@117743,2NUCT@237,4NGWZ@976,COG2067@1,COG2067@2	NA|NA|NA	I	Protein of unknown function (DUF2490)
MAG.T21.45_02623	504487.JCM19302_2703	1e-11	77.0	Flavobacteriia													Bacteria	1I3F7@117743,2DJI5@1,32UD2@2,4NT32@976	NA|NA|NA		
MAG.T21.45_02625	760192.Halhy_1829	1.2e-49	204.5	Bacteroidetes													Bacteria	4NNMV@976,COG0457@1,COG0457@2	NA|NA|NA	S	IMG reference gene
MAG.T21.45_02626	760192.Halhy_2408	3.1e-287	994.2	Sphingobacteriia	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10,6.1.1.20	ko:K01874,ko:K01890,ko:K06878	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R03660,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iEC042_1314.EC042_2346,iECUMN_1333.ECUMN_2446	Bacteria	1IPA1@117747,4NECB@976,COG0073@1,COG0073@2,COG0143@1,COG0143@2	NA|NA|NA	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MAG.T21.45_02627	760192.Halhy_2405	6.7e-57	227.3	Bacteria													Bacteria	COG3063@1,COG3063@2	NA|NA|NA	NU	photosynthesis
MAG.T21.45_02628	760192.Halhy_2420	7.6e-58	231.1	Bacteroidetes													Bacteria	28M5H@1,2ZAJ9@2,4NESS@976	NA|NA|NA		
MAG.T21.45_02629	760192.Halhy_2311	1.7e-252	879.0	Sphingobacteriia													Bacteria	1IP00@117747,4NEIG@976,COG1629@1,COG4771@2	NA|NA|NA	P	PFAM TonB-dependent Receptor Plug
MAG.T21.45_02630	760192.Halhy_2286	5.3e-278	963.4	Sphingobacteriia	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576	2.4.1.18,3.2.1.141	ko:K00700,ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110,R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000,ko04147		CBM48,GH13		Bacteria	1IQIR@117747,4NECZ@976,COG0296@1,COG0296@2	NA|NA|NA	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MAG.T21.45_02631	760192.Halhy_2389	2.2e-42	178.3	Sphingobacteriia	rbfA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360		ko:K02834					ko00000,ko03009				Bacteria	1ISV5@117747,4NSQJ@976,COG0858@1,COG0858@2	NA|NA|NA	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MAG.T21.45_02632	760192.Halhy_2390	5.9e-254	883.6	Sphingobacteriia	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1IP0N@117747,4NDZV@976,COG1200@1,COG1200@2	NA|NA|NA	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MAG.T21.45_02633	760192.Halhy_1326	5.7e-24	117.9	Sphingobacteriia													Bacteria	1IT3R@117747,4NTB0@976,COG2353@1,COG2353@2	NA|NA|NA	S	PFAM YceI-like domain
MAG.T21.45_02634	760192.Halhy_1327	1e-142	513.5	Sphingobacteriia													Bacteria	1INQ0@117747,2DBAQ@1,2Z848@2,4NFR9@976	NA|NA|NA		
MAG.T21.45_02635	1122176.KB903543_gene499	3e-35	155.2	Sphingobacteriia													Bacteria	1IT9I@117747,4NQKY@976,COG2353@1,COG2353@2	NA|NA|NA	S	PFAM YceI-like domain
MAG.T21.45_02636	1122176.KB903541_gene272	7.4e-30	137.5	Sphingobacteriia	acpT	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006553,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0019878,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.8.7	ko:K00997,ko:K06133	ko00770,map00770		R01625	RC00002	ko00000,ko00001,ko01000			iECNA114_1301.ECNA114_3584	Bacteria	1IRVW@117747,4NSBI@976,COG2091@1,COG2091@2	NA|NA|NA	H	Belongs to the P-Pant transferase superfamily
MAG.T21.45_02637	1122176.KB903541_gene276	2.6e-57	229.2	Sphingobacteriia			2.7.11.1	ko:K12132					ko00000,ko01000,ko01001				Bacteria	1IQXJ@117747,4NH20@976,COG2319@1,COG2319@2	NA|NA|NA	B	PFAM WD domain, G-beta repeat
MAG.T21.45_02638	290315.Clim_1284	1.9e-41	176.0	Chlorobi													Bacteria	1FF7S@1090,COG4704@1,COG4704@2	NA|NA|NA	S	Fibrobacter succinogenes major domain (Fib_succ_major)
MAG.T21.45_02639	760192.Halhy_5887	3.4e-70	271.6	Sphingobacteriia	cysH		1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQ9Q@117747,4NGVI@976,COG0175@1,COG0175@2	NA|NA|NA	EH	Reduction of activated sulfate into sulfite
MAG.T21.45_02640	760192.Halhy_2008	9.2e-186	656.8	Sphingobacteriia			3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100		R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002				Bacteria	1IQZU@117747,4NGUB@976,COG0308@1,COG0308@2	NA|NA|NA	E	Peptidase M1
MAG.T21.45_02641	1122176.KB903542_gene397	1.2e-11	78.2	Bacteroidetes													Bacteria	2DBNY@1,2ZA6F@2,4NTM4@976	NA|NA|NA		
MAG.T21.45_02642	760192.Halhy_2009	5.2e-166	590.5	Sphingobacteriia													Bacteria	1IQDJ@117747,4NGBE@976,COG1082@1,COG1082@2	NA|NA|NA	G	AP endonuclease
MAG.T21.45_02643	929562.Emtol_3366	6.1e-127	461.8	Cytophagia													Bacteria	47K3W@768503,4PKVH@976,COG1629@1,COG1629@2	NA|NA|NA	P	PFAM TonB-dependent Receptor Plug
MAG.T21.45_02644	760192.Halhy_3522	3.7e-13	81.3	Sphingobacteriia													Bacteria	1IUJT@117747,2DZQQ@1,32VGE@2,4NTQG@976	NA|NA|NA	S	Transmembrane family 220, helix
MAG.T21.45_02645	1185876.BN8_00164	1.2e-75	290.0	Cytophagia													Bacteria	47NJ6@768503,4NJ3Z@976,COG1082@1,COG1082@2	NA|NA|NA	G	Xylose isomerase domain protein TIM barrel
MAG.T21.45_02646	1237149.C900_05703	3.1e-112	411.8	Cytophagia				ko:K07577					ko00000				Bacteria	47JDM@768503,4NFN7@976,COG1236@1,COG1236@2	NA|NA|NA	J	exonuclease of the beta-lactamase fold involved in RNA processing
MAG.T21.45_02647	1530186.JQEY01000022_gene535	1.4e-175	622.9	Alphaproteobacteria	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430		R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400				Bacteria	1MV3S@1224,2TRQ9@28211,COG1793@1,COG1793@2	NA|NA|NA	L	DNA ligase
MAG.T21.45_02648	760192.Halhy_2292	3.9e-157	561.6	Sphingobacteriia													Bacteria	1IRN9@117747,4NG5Q@976,COG0308@1,COG0308@2	NA|NA|NA	M	PFAM Peptidase M1 membrane alanine aminopeptidase
MAG.T21.45_02649	760192.Halhy_6231	1.7e-164	585.9	Sphingobacteriia													Bacteria	1J0AW@117747,4P0XE@976,COG2211@1,COG2211@2	NA|NA|NA	G	MFS/sugar transport protein
MAG.T21.45_02650	760192.Halhy_0444	1.7e-38	165.2	Sphingobacteriia	maeB	GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114	1.1.1.38,1.1.1.40,2.3.1.8	ko:K00027,ko:K00029,ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,ko02020,map00430,map00620,map00640,map00680,map00710,map00720,map01100,map01120,map01200,map02020	M00169,M00172,M00357,M00579	R00214,R00216,R00230,R00921	RC00004,RC00105,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_1637	Bacteria	1IP28@117747,4NFUJ@976,COG0280@1,COG0280@2,COG0281@1,COG0281@2	NA|NA|NA	C	malic enzyme
MAG.T21.45_02652	388413.ALPR1_18633	1.1e-121	443.0	Cytophagia													Bacteria	47JDK@768503,4NDYY@976,COG2207@1,COG2207@2	NA|NA|NA	K	Transcriptional regulator, AraC family
MAG.T21.45_02653	1408473.JHXO01000002_gene4014	8.1e-84	317.0	Bacteroidia			1.1.1.100	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	2FRZY@200643,4NIAI@976,COG0300@1,COG0300@2	NA|NA|NA	S	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAG.T21.45_02654	2850.Phatr35460	1.3e-64	253.4	Eukaryota			1.1.1.2	ko:K00002	ko00010,ko00040,ko00561,ko00930,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00561,map00930,map01100,map01110,map01120,map01130,map01220	M00014	R00746,R01041,R01481,R05231	RC00087,RC00088,RC00099,RC00108	ko00000,ko00001,ko00002,ko01000,ko04147				Eukaryota	COG1028@1,KOG1208@2759	NA|NA|NA	IQ	oxidation-reduction process
MAG.T21.45_02656	1353276.JADR01000011_gene1593	2.9e-60	238.4	Flavobacteriia													Bacteria	1I1M8@117743,4NK59@976,COG1961@1,COG1961@2	NA|NA|NA	L	Resolvase, N terminal domain
MAG.T21.45_02658	880071.Fleli_0313	2.3e-35	155.2	Cytophagia													Bacteria	2DN0N@1,32URX@2,47S3N@768503,4NUM8@976	NA|NA|NA	S	Putative beta-lactamase-inhibitor-like, PepSY-like
MAG.T21.45_02659	709991.Odosp_2586	1.2e-18	99.4	Bacteroidia													Bacteria	2E6NI@1,2FRI9@200643,33190@2,4P5FB@976	NA|NA|NA	S	Psort location Cytoplasmic, score
MAG.T21.45_02660	1416760.AYMS01000018_gene1481	3.6e-118	431.8	Flavobacteriia													Bacteria	1II7U@117743,4NJYW@976,COG3950@1,COG3950@2	NA|NA|NA	S	AAA domain, putative AbiEii toxin, Type IV TA system
MAG.T21.45_02661	1416760.AYMS01000018_gene1482	1.2e-29	136.7	Flavobacteriia													Bacteria	1I9NG@117743,2CG3I@1,315GI@2,4NQVD@976	NA|NA|NA	S	Psort location Cytoplasmic, score 8.96
MAG.T21.45_02662	1121889.AUDM01000026_gene18	3.5e-25	120.6	Flavobacterium													Bacteria	1I32Z@117743,2NWSX@237,4NR5F@976,COG1396@1,COG1396@2	NA|NA|NA	K	Helix-turn-helix domain
MAG.T21.45_02663	340177.Cag_0912	5e-24	117.1	Bacteria													Bacteria	COG1848@1,COG1848@2	NA|NA|NA	G	Toxic component of a toxin-antitoxin (TA) module. An RNase
MAG.T21.45_02665	929562.Emtol_0970	1.7e-162	579.3	Cytophagia													Bacteria	47JSS@768503,4NEA7@976,COG0624@1,COG0624@2	NA|NA|NA	E	Peptidase dimerisation domain
MAG.T21.45_02668	997353.HMPREF9144_1782	9.1e-74	284.6	Bacteroidia													Bacteria	2G2PW@200643,4NJC9@976,COG1262@1,COG1262@2	NA|NA|NA	G	Sulfatase-modifying factor enzyme 1
MAG.T21.45_02670	1453498.LG45_01305	7.8e-255	886.3	Flavobacterium			1.13.12.16	ko:K00459	ko00910,map00910		R00025	RC02541,RC02759	ko00000,ko00001,ko01000				Bacteria	1HZ2A@117743,2NT89@237,4NEGW@976,COG2070@1,COG2070@2	NA|NA|NA	S	2-Nitropropane dioxygenase
MAG.T21.45_02671	1318628.MARLIPOL_07204	5e-11	75.5	Alteromonadaceae													Bacteria	1MU7P@1224,1RPVZ@1236,464QH@72275,COG0123@1,COG0123@2	NA|NA|NA	BQ	COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein
MAG.T21.45_02672	864073.HFRIS_021748	2.9e-114	418.7	Oxalobacteraceae	metK	GO:0000096,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006556,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009069,GO:0009108,GO:0009116,GO:0009119,GO:0009987,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0030554,GO:0030955,GO:0031420,GO:0032553,GO:0032555,GO:0032559,GO:0033353,GO:0034641,GO:0035639,GO:0036094,GO:0042278,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046872,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901605,GO:1901657	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000			iJN746.PP_4967,iYL1228.KPN_03375	Bacteria	1MUFQ@1224,2VH7U@28216,472RU@75682,COG0192@1,COG0192@2	NA|NA|NA	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MAG.T21.45_02673	509635.N824_02160	3.1e-55	222.2	Bacteroidetes													Bacteria	4PNC4@976,COG0596@1,COG0596@2	NA|NA|NA	S	Alpha/beta hydrolase family
MAG.T21.45_02674	1122605.KB893645_gene1191	0.0	1075.1	Sphingobacteriia													Bacteria	1IQ4S@117747,4NER2@976,COG3391@1,COG3391@2	NA|NA|NA	M	40-residue YVTN family beta-propeller repeat
MAG.T21.45_02675	641524.ADICYQ_1807	6.2e-10	69.3	Cytophagia													Bacteria	2DZK1@1,31FQC@2,47V6Q@768503,4NS1G@976	NA|NA|NA		
MAG.T21.45_02676	641524.ADICYQ_1814	3.4e-15	87.4	Cytophagia													Bacteria	2DZK1@1,31FQC@2,47V6Q@768503,4NS1G@976	NA|NA|NA		
MAG.T21.45_02677	1122176.KB903536_gene1761	2.3e-149	535.8	Bacteroidetes													Bacteria	28KN2@1,2ZA6D@2,4NG7P@976	NA|NA|NA		
MAG.T21.45_02678	1168034.FH5T_10310	4.9e-234	818.1	Bacteroidia													Bacteria	2FPRF@200643,4NEZ7@976,COG1413@1,COG1413@2	NA|NA|NA	C	Domain of Unknown Function (DUF1080)
MAG.T21.45_02679	1168034.FH5T_10315	9.8e-196	689.5	Bacteroidia													Bacteria	2FPMK@200643,4NGHJ@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_02680	760192.Halhy_4119	5.4e-99	367.9	Sphingobacteriia													Bacteria	1IRGS@117747,2DBNR@1,2ZA54@2,4NHW9@976	NA|NA|NA	S	Methane oxygenase PmoA
MAG.T21.45_02681	761193.Runsl_2283	2.6e-189	668.3	Cytophagia	uxaC	GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019585,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000			iPC815.YPO0579,iSbBS512_1146.SbBS512_E3528	Bacteria	47KAP@768503,4NFHS@976,COG1904@1,COG1904@2	NA|NA|NA	G	Glucuronate isomerase
MAG.T21.45_02682	1120968.AUBX01000009_gene717	0.0	1352.4	Cytophagia													Bacteria	47JHW@768503,4P1Z5@976,COG1629@1,COG4771@2	NA|NA|NA	P	PFAM TonB-dependent Receptor Plug
MAG.T21.45_02683	388413.ALPR1_10415	8.6e-232	809.7	Cytophagia				ko:K21572					ko00000,ko02000	8.A.46.1,8.A.46.3			Bacteria	47MR5@768503,4NEN3@976,COG0436@1,COG0436@2	NA|NA|NA	E	RagB SusD
MAG.T21.45_02684	760192.Halhy_2777	2.5e-55	221.9	Bacteroidetes													Bacteria	4NNKV@976,COG3828@1,COG3828@2	NA|NA|NA	S	Domain of Unknown Function (DUF1080)
MAG.T21.45_02685	929703.KE386491_gene2122	1.9e-179	635.6	Cytophagia													Bacteria	47KUI@768503,4NGDZ@976,COG1082@1,COG1082@2,COG2152@1,COG2152@2	NA|NA|NA	G	Domain of Unknown Function (DUF1080)
MAG.T21.45_02686	760192.Halhy_5869	1.9e-221	775.0	Sphingobacteriia													Bacteria	1IQ1R@117747,4NHDS@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase domain protein
MAG.T21.45_02687	1131812.JQMS01000001_gene2511	2e-25	122.1	Flavobacterium	yuxK												Bacteria	1I30U@117743,2NW8W@237,4NQ93@976,COG3011@1,COG3011@2	NA|NA|NA	S	Thiol-disulfide oxidoreductase
MAG.T21.45_02688	760192.Halhy_2384	4.8e-196	690.6	Sphingobacteriia	radA			ko:K04485					ko00000,ko03400				Bacteria	1IQC6@117747,4NEYA@976,COG1066@1,COG1066@2	NA|NA|NA	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MAG.T21.45_02689	1121957.ATVL01000006_gene3429	2.1e-42	179.1	Cytophagia	ywrF												Bacteria	47PFI@768503,4NG6I@976,COG1853@1,COG1853@2	NA|NA|NA	S	Flavin reductase like domain
MAG.T21.45_02690	760192.Halhy_2446	1.9e-62	246.1	Sphingobacteriia	dat		2.6.1.21,2.6.1.42	ko:K00824,ko:K00826	ko00270,ko00280,ko00290,ko00310,ko00330,ko00360,ko00472,ko00473,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00310,map00330,map00360,map00472,map00473,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01148,R01214,R01582,R02199,R02459,R02851,R02924,R05053,R10991	RC00006,RC00008,RC00025,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1IS3V@117747,4PFUA@976,COG0115@1,COG0115@2	NA|NA|NA	EH	Amino-transferase class IV
MAG.T21.45_02691	760192.Halhy_2334	0.0	1326.6	Sphingobacteriia	nrd		1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400				Bacteria	1IQ28@117747,4NEHQ@976,COG0209@1,COG0209@2	NA|NA|NA	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
MAG.T21.45_02692	760192.Halhy_2321	1.2e-34	153.3	Sphingobacteriia				ko:K06142					ko00000				Bacteria	1IS8U@117747,4NQGG@976,COG2825@1,COG2825@2	NA|NA|NA	M	PFAM outer membrane chaperone Skp (OmpH)
MAG.T21.45_02693	929562.Emtol_0864	8.4e-167	593.6	Cytophagia			3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600		R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000				Bacteria	47JKY@768503,4NFRB@976,COG3119@1,COG3119@2	NA|NA|NA	P	C-terminal region of aryl-sulfatase
MAG.T21.45_02694	1280001.BAOA01000126_gene1158	1.1e-12	80.1	Vibrionales	fcbC			ko:K07107					ko00000,ko01000				Bacteria	1RHCN@1224,1S4PS@1236,1XXBU@135623,COG0824@1,COG0824@2	NA|NA|NA	S	Thioesterase-like superfamily
MAG.T21.45_02695	760192.Halhy_1953	2.1e-108	398.7	Sphingobacteriia				ko:K03496					ko00000,ko03036,ko04812				Bacteria	1IW93@117747,4NGFE@976,COG1192@1,COG1192@2	NA|NA|NA	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family
MAG.T21.45_02697	643867.Ftrac_3376	6.8e-08	63.9	Cytophagia													Bacteria	2EG8H@1,33A0B@2,47SNZ@768503,4NY1M@976	NA|NA|NA		
MAG.T21.45_02698	760192.Halhy_1863	1e-55	223.4	Sphingobacteriia	ypmQ			ko:K07152,ko:K08976					ko00000,ko03029				Bacteria	1IT0K@117747,4NFH2@976,COG1999@1,COG1999@2	NA|NA|NA	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems
MAG.T21.45_02699	1122179.KB890425_gene3331	6.5e-95	354.0	Sphingobacteriia													Bacteria	1IQR6@117747,4NFNB@976,COG0330@1,COG0330@2	NA|NA|NA	O	COG0330 Membrane protease subunits stomatin prohibitin homologs
MAG.T21.45_02700	760192.Halhy_2291	4.7e-25	120.6	Bacteria				ko:K00406,ko:K12263	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156			ko00000,ko00001,ko00002	3.D.4.3			Bacteria	COG2010@1,COG2010@2	NA|NA|NA	C	Cytochrome c
MAG.T21.45_02701	760192.Halhy_2290	6.1e-79	301.2	Sphingobacteriia			1.1.1.219	ko:K00091					ko00000,ko01000				Bacteria	1IQ5S@117747,4NFZH@976,COG0451@1,COG0451@2	NA|NA|NA	M	NAD dependent epimerase dehydratase family
MAG.T21.45_02702	1122176.KB903565_gene3355	3.5e-159	568.5	Sphingobacteriia				ko:K03321					ko00000,ko02000	2.A.53.3			Bacteria	1IW25@117747,4NFX2@976,COG0659@1,COG0659@2	NA|NA|NA	P	COG0659 Sulfate permease and related
MAG.T21.45_02703	1250278.JQNQ01000001_gene415	2.3e-17	94.7	Flavobacteriia	yibN		2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122		R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000				Bacteria	1I53P@117743,4NSD1@976,COG0607@1,COG0607@2	NA|NA|NA	P	Sulfurtransferase
MAG.T21.45_02704	760192.Halhy_4818	2.4e-98	367.9	Sphingobacteriia													Bacteria	1IYSQ@117747,4P8KP@976,COG3210@1,COG3210@2	NA|NA|NA	U	IMG reference gene
MAG.T21.45_02705	1122176.KB903565_gene3350	7.8e-30	136.3	Sphingobacteriia	trxA			ko:K03671	ko04621,ko05418,map04621,map05418				ko00000,ko00001,ko03110				Bacteria	1ITPA@117747,4PKQI@976,COG0526@1,COG0526@2	NA|NA|NA	O	Thioredoxin
MAG.T21.45_02706	1122176.KB903565_gene3351	1.6e-52	212.6	Sphingobacteriia				ko:K07112					ko00000				Bacteria	1ITPY@117747,4NM6E@976,COG2391@1,COG2391@2	NA|NA|NA	S	Sulphur transport
MAG.T21.45_02707	1122176.KB903565_gene3352	1.1e-44	186.0	Sphingobacteriia				ko:K07112					ko00000				Bacteria	1IYBR@117747,4NQ9C@976,COG2391@1,COG2391@2	NA|NA|NA	S	Sulphur transport
MAG.T21.45_02708	760192.Halhy_2294	2.1e-97	362.8	Bacteroidetes													Bacteria	4P3MR@976,COG3746@1,COG3746@2	NA|NA|NA	P	phosphate-selective porin O and P
MAG.T21.45_02709	760192.Halhy_3689	2e-52	212.2	Sphingobacteriia				ko:K08973					ko00000				Bacteria	1IS6G@117747,4NEWG@976,COG1981@1,COG1981@2	NA|NA|NA	S	PFAM Uncharacterised protein family (UPF0093)
MAG.T21.45_02710	1121904.ARBP01000002_gene6687	3.5e-114	418.7	Cytophagia				ko:K02429					ko00000,ko02000	2.A.1.7			Bacteria	47M0J@768503,4NEYR@976,COG0738@1,COG0738@2	NA|NA|NA	G	Pfam Major Facilitator Superfamily
MAG.T21.45_02711	760192.Halhy_4190	3.2e-69	268.1	Sphingobacteriia			2.3.1.178,2.3.1.57,2.3.1.82	ko:K00657,ko:K06718,ko:K18816	ko00260,ko00330,ko01100,ko01120,ko04216,map00260,map00330,map01100,map01120,map04216	M00033,M00135	R01154,R06978	RC00004,RC00096	br01600,ko00000,ko00001,ko00002,ko01000,ko01504				Bacteria	1IR6P@117747,4PKMC@976,COG1670@1,COG1670@2	NA|NA|NA	J	acetyltransferase
MAG.T21.45_02712	760192.Halhy_4191	8.8e-170	603.2	Sphingobacteriia	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1INXV@117747,4NE3R@976,COG0137@1,COG0137@2	NA|NA|NA	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MAG.T21.45_02713	760192.Halhy_4192	2.4e-106	392.1	Sphingobacteriia	argC		1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPHE@117747,4NEQR@976,COG0002@1,COG0002@2	NA|NA|NA	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MAG.T21.45_02714	760192.Halhy_4193	1.9e-137	495.7	Sphingobacteriia	argD		2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1IQUC@117747,4NE0Z@976,COG4992@1,COG4992@2	NA|NA|NA	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MAG.T21.45_02715	760192.Halhy_4194	4.2e-119	434.5	Sphingobacteriia	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.11,2.1.3.3,2.1.3.9	ko:K00611,ko:K09065,ko:K13043	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245,R08937	RC00096	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQ2H@117747,4NEYX@976,COG0078@1,COG0078@2	NA|NA|NA	E	Belongs to the ATCase OTCase family
MAG.T21.45_02716	760192.Halhy_2042	4.7e-76	291.2	Sphingobacteriia	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0033554,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000			iAPECO1_1312.APECO1_2508,iB21_1397.B21_03793,iEC55989_1330.EC55989_4441,iECB_1328.ECB_03844,iECDH10B_1368.ECDH10B_4147,iECDH1ME8569_1439.ECDH1ME8569_3827,iECD_1391.ECD_03844,iECH74115_1262.ECH74115_5419,iECIAI1_1343.ECIAI1_4167,iECO103_1326.ECO103_4715,iECOK1_1307.ECOK1_4431,iECS88_1305.ECS88_4414,iECSE_1348.ECSE_4252,iETEC_1333.ETEC_4227,iEcE24377_1341.EcE24377A_4498,iEcHS_1320.EcHS_A4193,iEcolC_1368.EcolC_4057,iSbBS512_1146.SbBS512_E4445,iUMN146_1321.UM146_20050,iUMNK88_1353.UMNK88_4797,iUTI89_1310.UTI89_C4550,iY75_1357.Y75_RS17255	Bacteria	1IPBE@117747,4NDY8@976,COG0548@1,COG0548@2	NA|NA|NA	E	Belongs to the acetylglutamate kinase family. ArgB subfamily
MAG.T21.45_02717	760192.Halhy_2041	4.1e-110	404.8	Sphingobacteriia	argE		3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQBT@117747,4NE2G@976,COG0624@1,COG0624@2	NA|NA|NA	E	PFAM Peptidase family M20 M25 M40
MAG.T21.45_02718	760192.Halhy_2040	1.2e-159	569.7	Sphingobacteriia	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1INUE@117747,4NFCY@976,COG0165@1,COG0165@2	NA|NA|NA	E	argininosuccinate lyase
MAG.T21.45_02719	1239962.C943_02440	1.4e-34	152.5	Bacteroidetes			3.1.21.7	ko:K05982,ko:K07452					ko00000,ko01000,ko02048,ko03400				Bacteria	4NZHS@976,COG3695@1,COG3695@2	NA|NA|NA	L	enzyme binding
MAG.T21.45_02720	1346330.M472_06480	1.5e-99	369.8	Sphingobacteriia	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576										iNJ661.Rv2388c	Bacteria	1IR75@117747,4NFEE@976,COG0635@1,COG0635@2	NA|NA|NA	H	Involved in the biosynthesis of porphyrin-containing compound
MAG.T21.45_02721	760192.Halhy_4276	0.0	1247.6	Sphingobacteriia	sucA	GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000			iNJ661.Rv1248c,iSSON_1240.SSON_0677,iYL1228.KPN_00732	Bacteria	1IQYB@117747,4NEU9@976,COG0567@1,COG0567@2	NA|NA|NA	C	2-oxoglutarate dehydrogenase, E1
MAG.T21.45_02722	1122176.KB903532_gene2702	1.7e-22	111.7	Sphingobacteriia	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02968	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1ITAU@117747,4NSB1@976,COG0268@1,COG0268@2	NA|NA|NA	J	Binds directly to 16S ribosomal RNA
MAG.T21.45_02723	760192.Halhy_4325	1.3e-127	463.0	Sphingobacteriia				ko:K06076					ko00000,ko02000	1.B.9			Bacteria	1IQ3Y@117747,4NIU4@976,COG2067@1,COG2067@2	NA|NA|NA	I	protein CHP03519, membrane, Bacteroidetes
MAG.T21.45_02724	760192.Halhy_4324	2.1e-29	135.2	Bacteroidetes													Bacteria	4NUZA@976,COG1664@1,COG1664@2	NA|NA|NA	M	Integral membrane protein CcmA involved in cell shape determination
MAG.T21.45_02726	1270196.JCKI01000001_gene3991	1.3e-23	116.3	Sphingobacteriia	pccA		6.4.1.3	ko:K01965,ko:K02160	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000				Bacteria	1ITD7@117747,4NQ86@976,COG4770@1,COG4770@2	NA|NA|NA	I	Biotin lipoyl attachment domain-containing protein
MAG.T21.45_02727	760192.Halhy_4320	4.2e-204	718.0	Sphingobacteriia	dsbD		1.8.1.8	ko:K04084					ko00000,ko01000,ko03110	5.A.1.1			Bacteria	1IQXN@117747,4NEW6@976,COG4232@1,COG4232@2	NA|NA|NA	CO	Cytochrome c biogenesis protein transmembrane region
MAG.T21.45_02728	1122176.KB903540_gene39	9.9e-89	333.2	Sphingobacteriia	purQ	GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000				Bacteria	1IRA4@117747,4NFER@976,COG0047@1,COG0047@2	NA|NA|NA	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MAG.T21.45_02729	714943.Mucpa_3035	8.7e-12	78.2	Sphingobacteriia													Bacteria	1IPQD@117747,28H89@1,2Z7K8@2,4NEKX@976	NA|NA|NA		
MAG.T21.45_02730	760192.Halhy_4231	3.7e-123	448.4	Sphingobacteriia	ywfO	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576		ko:K06885					ko00000				Bacteria	1IQIS@117747,4NE1T@976,COG1078@1,COG1078@2	NA|NA|NA	S	phosphohydrolase
MAG.T21.45_02731	760192.Halhy_4232	2.3e-226	791.6	Sphingobacteriia	porX			ko:K03413	ko02020,ko02030,map02020,map02030	M00506			ko00000,ko00001,ko00002,ko02022,ko02035				Bacteria	1IP34@117747,4NE72@976,COG2204@1,COG2204@2	NA|NA|NA	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
MAG.T21.45_02733	760192.Halhy_4279	1.5e-89	336.3	Sphingobacteriia	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680		ko:K03118	ko03060,ko03070,map03060,map03070	M00336			ko00000,ko00001,ko00002,ko02044	2.A.64			Bacteria	1INR5@117747,4NEKM@976,COG0805@1,COG0805@2	NA|NA|NA	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MAG.T21.45_02735	760192.Halhy_4277	1.2e-92	347.1	Bacteria			3.2.1.4,5.2.1.8	ko:K01179,ko:K03768,ko:K08738	ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko03110	3.D.4.6	GH5,GH9		Bacteria	COG3291@1,COG3291@2,COG3866@1,COG3866@2	NA|NA|NA	G	Pectate lyase
MAG.T21.45_02736	760192.Halhy_4342	6.8e-266	924.5	Bacteroidetes													Bacteria	4PKBQ@976,COG3209@1,COG3209@2,COG4886@1,COG4886@2	NA|NA|NA	M	SPTR CHU large protein
MAG.T21.45_02737	760192.Halhy_4343	5.4e-16	91.7	Bacteria	dacA1		3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100				ko00000,ko00001,ko01000,ko01002,ko01011				Bacteria	COG3087@1,COG3087@2,COG4232@1,COG4232@2	NA|NA|NA	CO	protein-disulfide reductase activity
MAG.T21.45_02739	760192.Halhy_2514	2.3e-158	565.8	Sphingobacteriia	msbA			ko:K02021,ko:K06147,ko:K06148,ko:K11085	ko02010,map02010				ko00000,ko00001,ko01000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21			Bacteria	1IQ58@117747,4NE2D@976,COG1132@1,COG1132@2	NA|NA|NA	V	ABC transporter
MAG.T21.45_02740	760192.Halhy_2515	1.9e-221	775.0	Sphingobacteriia	accC		6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000				Bacteria	1INM0@117747,4NFEQ@976,COG0439@1,COG0439@2	NA|NA|NA	I	acetyl-CoA carboxylase, biotin carboxylase
MAG.T21.45_02741	760192.Halhy_2516	8.4e-45	186.8	Sphingobacteriia	accB		2.3.1.12,4.1.1.3	ko:K00627,ko:K01571,ko:K02160	ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00307,M00376	R00209,R00217,R00742,R02569	RC00004,RC00040,RC00367,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1			Bacteria	1ISET@117747,4NM8U@976,COG0511@1,COG0511@2	NA|NA|NA	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MAG.T21.45_02742	760192.Halhy_2517	5.7e-71	273.9	Sphingobacteriia	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02356					ko00000,ko03012				Bacteria	1IP45@117747,4NDXA@976,COG0231@1,COG0231@2	NA|NA|NA	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MAG.T21.45_02743	760192.Halhy_2518	4.9e-142	510.8	Sphingobacteriia	fabH		2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1IPRR@117747,4NEYH@976,COG0332@1,COG0332@2	NA|NA|NA	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MAG.T21.45_02744	1122176.KB903542_gene329	9.5e-158	563.5	Sphingobacteriia													Bacteria	1IQ8J@117747,4NEF3@976,COG0591@1,COG0591@2	NA|NA|NA	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MAG.T21.45_02745	760192.Halhy_2520	1.3e-41	176.4	Sphingobacteriia	lspA		3.4.23.36	ko:K03101	ko03060,map03060				ko00000,ko00001,ko01000,ko01002				Bacteria	1ISWW@117747,4NNP3@976,COG0597@1,COG0597@2	NA|NA|NA	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MAG.T21.45_02746	1122176.KB903561_gene3572	2.9e-139	501.9	Sphingobacteriia													Bacteria	1IPAU@117747,4NE2H@976,COG5505@1,COG5505@2	NA|NA|NA	S	Protein of unknown function (DUF819)
MAG.T21.45_02747	1122176.KB903532_gene2559	3.8e-62	245.7	Sphingobacteriia	XK27_09805												Bacteria	1IYYK@117747,4NJPY@976,COG4249@1,COG4249@2,COG4642@1,COG4642@2	NA|NA|NA	S	Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases.
MAG.T21.45_02748	760192.Halhy_3312	3.2e-69	269.6	Sphingobacteriia	XK27_09805												Bacteria	1IZAN@117747,4NKYQ@976,COG4249@1,COG4249@2,COG4642@1,COG4642@2	NA|NA|NA	L	Caspase domain
MAG.T21.45_02749	1122176.KB903560_gene3561	4.4e-36	157.5	Sphingobacteriia	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904		ko:K02990	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011,ko03029				Bacteria	1ISJI@117747,4NQ9W@976,COG0360@1,COG0360@2	NA|NA|NA	J	Binds together with S18 to 16S ribosomal RNA
MAG.T21.45_02750	760192.Halhy_3310	9.3e-40	169.1	Sphingobacteriia	rpsR	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02963	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1ISSH@117747,4NSAR@976,COG0238@1,COG0238@2	NA|NA|NA	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MAG.T21.45_02751	760192.Halhy_3309	5.7e-42	177.2	Sphingobacteriia	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02939	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IRUM@117747,4NNRP@976,COG0359@1,COG0359@2	NA|NA|NA	J	binds to the 23S rRNA
MAG.T21.45_02752	760192.Halhy_3494	1.2e-44	186.8	Sphingobacteriia				ko:K07043					ko00000				Bacteria	1IUYI@117747,4NIY4@976,COG1451@1,COG1451@2	NA|NA|NA	S	Protein of unknown function DUF45
MAG.T21.45_02753	760192.Halhy_3493	4.5e-133	481.1	Sphingobacteriia	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1IP7N@117747,4NE06@976,COG1932@1,COG1932@2	NA|NA|NA	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MAG.T21.45_02756	525897.Dbac_0130	5.7e-12	77.4	Bacteria													Bacteria	COG0138@1,COG0138@2	NA|NA|NA	F	bifunctional purine biosynthesis protein purh
MAG.T21.45_02757	1120980.JQKH01000020_gene2452	1.8e-10	72.0	Bacteria	Z012_00950		3.1.21.3	ko:K01154,ko:K07076					ko00000,ko01000,ko02048				Bacteria	COG1708@1,COG1708@2	NA|NA|NA	S	nucleotidyltransferase activity
MAG.T21.45_02758	1415755.JQLV01000001_gene1109	1.5e-38	166.0	Gammaproteobacteria													Bacteria	1NBPF@1224,1S7DZ@1236,2C4WJ@1,32Z4K@2	NA|NA|NA		
MAG.T21.45_02759	748658.KB907313_gene2299	2.6e-25	121.3	Chromatiales													Bacteria	1N7SN@1224,1SCCH@1236,1WZEJ@135613,COG1708@1,COG1708@2	NA|NA|NA	S	PFAM DNA polymerase, beta domain protein region
MAG.T21.45_02760	1305737.JAFX01000001_gene1344	1.8e-13	81.3	Cytophagia													Bacteria	2AE47@1,313XF@2,47WB2@768503,4NYMZ@976	NA|NA|NA	S	Domain of unknown function (DUF4160)
MAG.T21.45_02761	1305737.JAFX01000001_gene1343	3.6e-51	208.0	Bacteroidetes	merR												Bacteria	4NQCR@976,COG3620@1,COG3620@2	NA|NA|NA	K	transcriptional regulator
MAG.T21.45_02763	533240.CRC_02129	1.5e-190	672.5	Cyanobacteria													Bacteria	1GC3Q@1117,COG1672@1,COG1672@2	NA|NA|NA	S	PD-(D/E)XK nuclease superfamily
MAG.T21.45_02764	533240.CRC_02129	5.5e-49	200.7	Cyanobacteria													Bacteria	1GC3Q@1117,COG1672@1,COG1672@2	NA|NA|NA	S	PD-(D/E)XK nuclease superfamily
MAG.T21.45_02765	1218103.CIN01S_02_01460	6.4e-145	520.4	Chryseobacterium													Bacteria	1HXKG@117743,3ZPJM@59732,4NH44@976,COG0464@1,COG0464@2	NA|NA|NA	O	Protein of unknown function (DUF815)
MAG.T21.45_02766	1121896.JMLU01000009_gene1659	2.5e-12	78.2	Flavobacterium			3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1HYN7@117743,2NXRI@237,4NGFJ@976,COG2865@1,COG2865@2	NA|NA|NA	K	Putative ATP-dependent DNA helicase recG C-terminal
MAG.T21.45_02767	421531.IX38_09730	1.5e-122	446.0	Chryseobacterium													Bacteria	1HZKE@117743,3ZR3M@59732,4NGY8@976,COG4804@1,COG4804@2	NA|NA|NA	S	Protein of unknown function (DUF1016)
MAG.T21.45_02769	1121098.HMPREF1534_01643	1.6e-243	850.1	Bacteroidaceae	recQ		3.6.4.12	ko:K03654	ko03018,map03018				ko00000,ko00001,ko01000,ko03400				Bacteria	2FPYY@200643,4ASXM@815,4NIG1@976,COG0514@1,COG0514@2	NA|NA|NA	L	helicase superfamily c-terminal domain
MAG.T21.45_02771	338966.Ppro_0181	2.1e-17	94.7	Proteobacteria													Bacteria	1NGYR@1224,2E37J@1,32Y79@2	NA|NA|NA		
MAG.T21.45_02772	1267211.KI669560_gene2129	5e-103	380.6	Bacteroidetes													Bacteria	4NJT3@976,COG1002@1,COG1002@2	NA|NA|NA	V	Psort location Cytoplasmic, score 8.96
MAG.T21.45_02774	761193.Runsl_3841	2.2e-189	668.7	Bacteroidetes			2.1.1.72,3.1.21.4	ko:K00571,ko:K01155,ko:K03427					ko00000,ko01000,ko02048				Bacteria	4NGGH@976,COG0286@1,COG0286@2	NA|NA|NA	L	Eco57I restriction endonuclease
MAG.T21.45_02775	991.IW20_17410	2.8e-122	444.9	Flavobacterium													Bacteria	1IJ7P@117743,2NV2N@237,4NIG0@976,COG3617@1,COG3617@2	NA|NA|NA	K	BRO family, N-terminal domain
MAG.T21.45_02776	1267211.KI669560_gene2132	0.0	1474.5	Bacteroidetes													Bacteria	4NE28@976,COG1061@1,COG1061@2	NA|NA|NA	L	restriction
MAG.T21.45_02777	153948.NAL212_2557	1.4e-288	998.4	Betaproteobacteria	yfjM												Bacteria	1R5X1@1224,2VQ73@28216,COG1479@1,COG1479@2,COG3472@1,COG3472@2	NA|NA|NA	S	Protein of unknown function DUF262
MAG.T21.45_02778	926559.JoomaDRAFT_1100	3e-36	157.9	Flavobacteriia													Bacteria	1I4NA@117743,2E08H@1,32VW5@2,4NT92@976	NA|NA|NA		
MAG.T21.45_02780	1121904.ARBP01000001_gene6011	1.9e-74	286.6	Bacteroidetes													Bacteria	2DM8V@1,3274K@2,4NM1U@976	NA|NA|NA	S	Bacteriophage abortive infection AbiH
MAG.T21.45_02781	1233951.IO90_12000	1.2e-34	154.1	Flavobacteriia													Bacteria	1I6YI@117743,2E7TQ@1,3328T@2,4NUN1@976	NA|NA|NA		
MAG.T21.45_02783	761193.Runsl_5903	4.7e-109	401.0	Cytophagia	M1-769												Bacteria	47M4W@768503,4NE62@976,COG1533@1,COG1533@2	NA|NA|NA	L	SMART Elongator protein 3 MiaB NifB
MAG.T21.45_02784	1120966.AUBU01000003_gene1482	2.3e-217	762.3	Cytophagia			3.6.4.12	ko:K16899					ko00000,ko01000,ko03400				Bacteria	47TJS@768503,4NJXU@976,COG0210@1,COG0210@2	NA|NA|NA	L	UvrD/REP helicase N-terminal domain
MAG.T21.45_02785	1121098.HMPREF1534_01645	4.9e-27	127.5	Bacteroidaceae													Bacteria	2A8DN@1,2FXWF@200643,30XFD@2,4AUS5@815,4PAW8@976	NA|NA|NA		
MAG.T21.45_02786	1408473.JHXO01000002_gene3926	9.1e-138	496.9	Bacteroidia													Bacteria	2FMGI@200643,4NEB2@976,COG0738@1,COG0738@2	NA|NA|NA	G	Transporter, major facilitator family protein
MAG.T21.45_02787	880073.Calab_3081	3.4e-80	305.1	Bacteria			2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	COG1940@1,COG1940@2	NA|NA|NA	GK	ROK family
MAG.T21.45_02788	1122176.KB903619_gene5399	1e-39	170.2	Sphingobacteriia	yhcW	GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0044237,GO:0050308,GO:0050309	3.1.3.96,5.4.2.6	ko:K01838,ko:K07025,ko:K17623	ko00500,map00500		R02728,R11180,R11310	RC00017,RC00408	ko00000,ko00001,ko01000,ko01009				Bacteria	1IZ8D@117747,4NMJT@976,COG0637@1,COG0637@2	NA|NA|NA	S	Haloacid dehalogenase-like hydrolase
MAG.T21.45_02789	760192.Halhy_5356	3e-26	125.2	Bacteroidetes													Bacteria	2DDTY@1,2ZJ9C@2,4P7MU@976	NA|NA|NA		
MAG.T21.45_02790	1121957.ATVL01000011_gene3930	2.4e-13	83.6	Bacteroidetes													Bacteria	2F9D3@1,341PZ@2,4P3ZH@976	NA|NA|NA		
MAG.T21.45_02791	760192.Halhy_4234	1e-15	89.0	Sphingobacteriia				ko:K03929					ko00000,ko01000		CE10		Bacteria	1IRFR@117747,4NF5N@976,COG2272@1,COG2272@2	NA|NA|NA	I	Belongs to the type-B carboxylesterase lipase family
MAG.T21.45_02792	760192.Halhy_0760	9.2e-55	219.9	Sphingobacteriia													Bacteria	1IZ3F@117747,298PG@1,2ZVTY@2,4PJH3@976	NA|NA|NA		
MAG.T21.45_02793	1178825.ALIH01000004_gene2923	2e-57	228.8	Flavobacteriia													Bacteria	1I23S@117743,4NP2C@976,COG2318@1,COG2318@2	NA|NA|NA	S	DinB superfamily
MAG.T21.45_02794	755732.Fluta_3954	3.1e-151	541.2	Bacteroidetes		GO:0003674,GO:0003824,GO:0016787											Bacteria	4NM26@976,COG0596@1,COG0596@2	NA|NA|NA	S	Hydrolase or acyltransferase (Alpha beta hydrolase superfamily)-like protein
MAG.T21.45_02795	714943.Mucpa_2444	1e-92	347.1	Bacteria													Bacteria	COG4637@1,COG4637@2	NA|NA|NA	L	Psort location Cytoplasmic, score
MAG.T21.45_02797	313595.P700755_004059	4.3e-65	254.2	Bacteroidetes													Bacteria	2BFRA@1,329K3@2,4PPXW@976	NA|NA|NA		
MAG.T21.45_02798	1123277.KB893172_gene764	2.1e-10	70.9	Bacteroidetes													Bacteria	2DCN7@1,2ZEQM@2,4P8AT@976	NA|NA|NA		
MAG.T21.45_02799	938709.AUSH02000018_gene1138	1.8e-88	332.4	Bacteroidetes													Bacteria	4NFNB@976,COG0330@1,COG0330@2	NA|NA|NA	O	COG0330 Membrane protease subunits stomatin prohibitin homologs
MAG.T21.45_02800	1122176.KB903555_gene3777	3.8e-81	308.5	Bacteroidetes													Bacteria	4NI2T@976,COG3292@1,COG3292@2	NA|NA|NA	T	Two component regulator propeller
MAG.T21.45_02801	760192.Halhy_6788	7.5e-176	623.2	Sphingobacteriia	fic												Bacteria	1IWWY@117747,4NF0H@976,COG3177@1,COG3177@2	NA|NA|NA	S	Domain of unknown function (DUF4172)
MAG.T21.45_02802	1144313.PMI10_02213	3.9e-74	284.3	Flavobacterium													Bacteria	1IAQW@117743,2CMS6@1,2NWVT@237,32SFE@2,4NWI0@976	NA|NA|NA		
MAG.T21.45_02803	1450525.JATV01000016_gene3014	3.8e-36	157.9	Flavobacterium													Bacteria	1IE5A@117743,2NZVY@237,4PJFH@976,COG4430@1,COG4430@2	NA|NA|NA	S	Bacteriocin-protection, YdeI or OmpD-Associated
MAG.T21.45_02804	761193.Runsl_3844	1.3e-35	155.2	Cytophagia				ko:K06996					ko00000				Bacteria	47S1F@768503,4NMFV@976,COG3324@1,COG3324@2	NA|NA|NA	S	Glyoxalase-like domain
MAG.T21.45_02805	1157490.EL26_05100	2.8e-155	555.1	Bacilli			3.6.4.12,3.6.4.13	ko:K03655,ko:K05592	ko03018,ko03440,map03018,map03440				ko00000,ko00001,ko01000,ko03009,ko03019,ko03400				Bacteria	1TSPK@1239,4HF0C@91061,COG0724@1,COG0724@2,COG2865@1,COG2865@2	NA|NA|NA	K	Putative ATP-dependent DNA helicase recG C-terminal
MAG.T21.45_02806	1123276.KB893245_gene1318	8.8e-159	566.6	Cytophagia													Bacteria	47KFM@768503,4NF61@976,COG2133@1,COG2133@2	NA|NA|NA	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
MAG.T21.45_02807	1089547.KB913013_gene1834	0.0	1302.7	Cytophagia													Bacteria	47K6B@768503,4NHMI@976,COG1413@1,COG1413@2,COG2133@1,COG2133@2,COG3794@1,COG3794@2	NA|NA|NA	CG	Membrane-bound dehydrogenase domain protein
MAG.T21.45_02808	616991.JPOO01000001_gene4016	2e-72	278.9	Bacteroidetes			1.1.9.1	ko:K17760					ko00000,ko01000				Bacteria	4NN0I@976,COG2010@1,COG2010@2	NA|NA|NA	C	Domain of Unknown Function (DUF1080)
MAG.T21.45_02809	1089547.KB913013_gene3720	6e-92	344.7	Cytophagia	mntH												Bacteria	47MUM@768503,4NENE@976,COG1914@1,COG1914@2	NA|NA|NA	P	PFAM natural resistance-associated macrophage protein
MAG.T21.45_02810	760192.Halhy_3338	5.9e-46	191.4	Bacteroidetes	mvk		1.1.1.88,2.3.3.10,2.7.1.36	ko:K00054,ko:K00869,ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,ko04146,map00072,map00280,map00650,map00900,map01100,map01110,map01130,map04146	M00088,M00095	R01978,R02081,R02245	RC00002,RC00004,RC00017,RC00503,RC00644	ko00000,ko00001,ko00002,ko01000				Bacteria	4NDYJ@976,COG1577@1,COG1577@2	NA|NA|NA	I	mevalonate kinase
MAG.T21.45_02812	760192.Halhy_3160	6.1e-112	410.6	Sphingobacteriia	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100		R00104	RC00002,RC00078	ko00000,ko00001,ko01000			iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895	Bacteria	1IPBF@117747,4NFG5@976,COG0061@1,COG0061@2	NA|NA|NA	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MAG.T21.45_02813	1122176.KB903542_gene337	4.3e-83	315.5	Sphingobacteriia													Bacteria	1IWQ4@117747,4NF9Y@976,COG4775@1,COG4775@2	NA|NA|NA	M	COG4775 Outer membrane protein protective antigen OMA87
MAG.T21.45_02814	760192.Halhy_3171	3.9e-47	194.9	Sphingobacteriia													Bacteria	1IRUD@117747,4NF8G@976,COG0517@1,COG0517@2	NA|NA|NA	S	CBS domain
MAG.T21.45_02815	1122176.KB903549_gene1278	3.4e-47	195.3	Bacteroidetes	yozV												Bacteria	4NW91@976,COG0457@1,COG0457@2,COG2314@1,COG2314@2	NA|NA|NA	S	TM2 domain
MAG.T21.45_02816	760192.Halhy_3173	7.7e-132	477.2	Sphingobacteriia	rsbU		3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021				Bacteria	1IR5G@117747,4NI98@976,COG2208@1,COG2208@2	NA|NA|NA	KT	Serine phosphatase RsbU regulator of sigma subunit
MAG.T21.45_02817	313606.M23134_08101	3.9e-35	154.1	Cytophagia	ypjD		2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000				Bacteria	47QEV@768503,4NQ3H@976,COG1694@1,COG1694@2	NA|NA|NA	S	PFAM MazG nucleotide pyrophosphohydrolase
MAG.T21.45_02818	1270193.JARP01000001_gene3390	9.3e-48	196.4	Flavobacterium	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360		ko:K07560					ko00000,ko01000,ko03016				Bacteria	1I1XN@117743,2NW14@237,4NNFF@976,COG1490@1,COG1490@2	NA|NA|NA	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MAG.T21.45_02819	1122176.KB903555_gene3759	2e-33	149.4	Sphingobacteriia	yoqW												Bacteria	1IYGZ@117747,4NKPN@976,COG2135@1,COG2135@2	NA|NA|NA	S	Belongs to the SOS response-associated peptidase family
MAG.T21.45_02820	760192.Halhy_3001	2.4e-110	405.6	Sphingobacteriia	ctaA			ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4			Bacteria	1IQDH@117747,4NIT1@976,COG1612@1,COG1612@2	NA|NA|NA	O	protein required for cytochrome oxidase assembly
MAG.T21.45_02821	760192.Halhy_3002	5.8e-78	297.4	Sphingobacteriia	aat	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096	2.3.2.6	ko:K00684			R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000				Bacteria	1IP1V@117747,4NG3A@976,COG2360@1,COG2360@2	NA|NA|NA	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MAG.T21.45_02822	760192.Halhy_3003	8.5e-91	341.3	Sphingobacteriia													Bacteria	1INUW@117747,4NED7@976,COG0739@1,COG0739@2	NA|NA|NA	M	Peptidase, M23
MAG.T21.45_02823	1121904.ARBP01000002_gene7166	9.2e-43	179.9	Cytophagia	bcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.11.1.15	ko:K03564					ko00000,ko01000				Bacteria	47PUA@768503,4NNGK@976,COG1225@1,COG1225@2	NA|NA|NA	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MAG.T21.45_02824	1123277.KB893179_gene3116	1.2e-91	343.2	Cytophagia													Bacteria	47KF3@768503,4NG49@976,COG0647@1,COG0647@2	NA|NA|NA	G	Haloacid dehalogenase-like hydrolase
MAG.T21.45_02825	1123248.KB893385_gene4848	1.2e-135	489.6	Sphingobacteriia													Bacteria	1IRG4@117747,4NITA@976,COG2334@1,COG2334@2	NA|NA|NA	S	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MAG.T21.45_02826	153721.MYP_1075	5.5e-85	320.9	Cytophagia	map2		3.4.11.18	ko:K01265					ko00000,ko01000,ko01002				Bacteria	47KJV@768503,4NEAT@976,COG0024@1,COG0024@2	NA|NA|NA	E	TIGRFAM methionine aminopeptidase, type I
MAG.T21.45_02827	1237149.C900_04396	1.9e-12	78.2	Cytophagia	moaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.12	ko:K03636,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122		R09395	RC02507	ko00000,ko00001,ko01000				Bacteria	47RZY@768503,4NUVK@976,COG1977@1,COG1977@2	NA|NA|NA	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MAG.T21.45_02828	1122176.KB903550_gene4323	2.2e-33	148.7	Sphingobacteriia	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	2.1.1.63	ko:K00567					ko00000,ko01000,ko03400				Bacteria	1IUBZ@117747,4NFYC@976,COG0350@1,COG0350@2	NA|NA|NA	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MAG.T21.45_02829	929703.KE386491_gene506	2.6e-79	302.4	Cytophagia				ko:K02557	ko02030,ko02040,map02030,map02040				ko00000,ko00001,ko02000,ko02035	1.A.30.1			Bacteria	47XQX@768503,4NF2Y@976,COG1360@1,COG1360@2	NA|NA|NA	N	OmpA MotB domain protein
MAG.T21.45_02830	760192.Halhy_0592	1.3e-256	892.5	Sphingobacteriia													Bacteria	1IPMK@117747,4NFQ6@976,COG2091@1,COG2091@2	NA|NA|NA	H	lysine biosynthetic process via aminoadipic acid
MAG.T21.45_02831	760192.Halhy_2700	1.2e-84	320.9	Sphingobacteriia													Bacteria	1IR9Z@117747,4NERG@976,COG0457@1,COG0457@2	NA|NA|NA	S	Oxygen tolerance
MAG.T21.45_02832	760192.Halhy_2697	3.2e-69	269.6	Sphingobacteriia	batB			ko:K07114					ko00000,ko02000	1.A.13.2.2,1.A.13.2.3			Bacteria	1IR1C@117747,4NF7Y@976,COG2304@1,COG2304@2	NA|NA|NA	S	von Willebrand factor, type A
MAG.T21.45_02833	1122176.KB903555_gene3784	4.1e-88	331.6	Sphingobacteriia	batA			ko:K07114					ko00000,ko02000	1.A.13.2.2,1.A.13.2.3			Bacteria	1IP6P@117747,4NDUC@976,COG2304@1,COG2304@2	NA|NA|NA	S	von Willebrand factor, type A
MAG.T21.45_02834	641143.HMPREF9331_00691	2.5e-18	99.8	Capnocytophaga	ccmH	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564		ko:K02198,ko:K02200,ko:K04016,ko:K04017,ko:K04018			R05712	RC00176	ko00000,ko02000	9.B.14.1			Bacteria	1EQSU@1016,1HY3G@117743,4NGHU@976,COG3088@1,COG3088@2	NA|NA|NA	O	Psort location CytoplasmicMembrane, score
MAG.T21.45_02835	1122176.KB903555_gene3786	5.7e-102	377.5	Sphingobacteriia		GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944											Bacteria	1IR6K@117747,4NE2N@976,COG1721@1,COG1721@2	NA|NA|NA	S	protein (some members contain a von Willebrand factor type A (vWA) domain)
MAG.T21.45_02836	760192.Halhy_2693	4.6e-140	504.2	Sphingobacteriia	moxR			ko:K03924					ko00000,ko01000				Bacteria	1IPXJ@117747,4NDVZ@976,COG0714@1,COG0714@2	NA|NA|NA	S	PFAM ATPase family associated with various cellular activities (AAA)
MAG.T21.45_02839	760192.Halhy_2557	7.6e-103	380.2	Sphingobacteriia	lptB	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351		ko:K01990,ko:K06861	ko02010,map02010	M00254,M00320			ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1,3.A.1			Bacteria	1IQQ1@117747,4NDUG@976,COG1137@1,COG1137@2	NA|NA|NA	S	ABC transporter
MAG.T21.45_02841	1122176.KB903548_gene1213	3.1e-60	239.2	Sphingobacteriia	lytG			ko:K02395,ko:K14196	ko05150,map05150				ko00000,ko00001,ko02035				Bacteria	1IP5H@117747,4NEER@976,COG1388@1,COG1388@2,COG1705@1,COG1705@2	NA|NA|NA	NU	COG1705 Muramidase (flagellum-specific)
MAG.T21.45_02842	926550.CLDAP_14260	9.5e-96	357.1	Chloroflexi													Bacteria	2G5RM@200795,COG3173@1,COG3173@2	NA|NA|NA	S	Phosphotransferase enzyme family
MAG.T21.45_02843	1121904.ARBP01000003_gene6425	1.6e-134	486.1	Cytophagia	fadE1		1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000				Bacteria	47MEG@768503,4NH3I@976,COG1960@1,COG1960@2	NA|NA|NA	I	Acyl-CoA dehydrogenase, C-terminal domain
MAG.T21.45_02844	760192.Halhy_3523	1.2e-64	253.1	Sphingobacteriia	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501					ko00000,ko01000,ko03009,ko03036				Bacteria	1IR77@117747,4NEJG@976,COG0357@1,COG0357@2	NA|NA|NA	J	Specifically methylates the N7 position of a guanine in 16S rRNA
MAG.T21.45_02845	886377.Murru_3199	2e-69	268.9	Flavobacteriia	ydeI												Bacteria	1HXYY@117743,4NG4C@976,COG4430@1,COG4430@2	NA|NA|NA	S	Bacteriocin-protection, YdeI or OmpD-Associated
MAG.T21.45_02846	1121897.AUGO01000005_gene140	9.7e-138	496.9	Flavobacterium	ykbA			ko:K03294					ko00000	2.A.3.2			Bacteria	1HY25@117743,2NSIM@237,4NH7J@976,COG0531@1,COG0531@2	NA|NA|NA	E	amino acid
MAG.T21.45_02847	1122176.KB903531_gene3102	8.1e-90	337.8	Bacteroidetes													Bacteria	28IIT@1,2Z8JU@2,4NJ1B@976	NA|NA|NA		
MAG.T21.45_02848	1124780.ANNU01000030_gene1145	3.2e-80	305.1	Cytophagia													Bacteria	47M6H@768503,4NGZI@976,COG1028@1,COG1028@2	NA|NA|NA	IQ	Enoyl-(Acyl carrier protein) reductase
MAG.T21.45_02849	760192.Halhy_5189	6e-152	544.3	Bacteroidetes				ko:K11928,ko:K14392					ko00000,ko02000	2.A.21.1,2.A.21.2			Bacteria	4NIXN@976,COG0591@1,COG0591@2	NA|NA|NA	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MAG.T21.45_02850	760192.Halhy_1938	2.7e-119	435.3	Bacteroidetes	fabH		2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	4NKVP@976,COG0332@1,COG0332@2	NA|NA|NA	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal
MAG.T21.45_02851	1122176.KB903531_gene3096	7.2e-150	537.3	Bacteroidetes	MA20_22985		6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1			Bacteria	4NFPF@976,COG0318@1,COG0318@2	NA|NA|NA	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II
MAG.T21.45_02852	1453500.AT05_05905	1.3e-27	129.8	Bacteria													Bacteria	2CS90@1,32SQN@2	NA|NA|NA		
MAG.T21.45_02853	880073.Calab_0160	4.2e-156	558.1	Bacteria													Bacteria	28NE8@1,2ZBGT@2	NA|NA|NA		
MAG.T21.45_02854	880073.Calab_0161	4.1e-82	311.6	unclassified Bacteria													Bacteria	2NQ6U@2323,COG2267@1,COG2267@2	NA|NA|NA	I	Alpha/beta hydrolase family
MAG.T21.45_02855	1230343.CANP01000042_gene3124	8.4e-98	364.0	Gammaproteobacteria													Bacteria	1MVPR@1224,1RYK4@1236,COG1680@1,COG1680@2	NA|NA|NA	V	Beta-lactamase
MAG.T21.45_02856	1189612.A33Q_2767	3.3e-123	448.0	Cytophagia	dinD			ko:K07741,ko:K14623					ko00000,ko03400				Bacteria	47TBU@768503,4NJ37@976,COG3645@1,COG3645@2	NA|NA|NA	S	DNA-damage-inducible protein D
MAG.T21.45_02857	1123057.P872_08845	6.8e-153	547.4	Cytophagia	M1-1044												Bacteria	47M1T@768503,4NEIV@976,COG0397@1,COG0397@2	NA|NA|NA	S	Belongs to the UPF0061 (SELO) family
MAG.T21.45_02858	504472.Slin_6604	3.8e-63	248.4	Cytophagia	ugpQ		3.1.4.46	ko:K01126	ko00564,map00564		R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000				Bacteria	47XAH@768503,4NW6B@976,COG0584@1,COG0584@2	NA|NA|NA	C	Glycerophosphoryl diester phosphodiesterase family
MAG.T21.45_02859	504472.Slin_6242	4.5e-276	957.2	Cytophagia			1.3.99.16	ko:K07303					ko00000,ko01000				Bacteria	47KPV@768503,4NFFU@976,COG1529@1,COG1529@2	NA|NA|NA	C	Aldehyde oxidase and xanthine dehydrogenase molybdopterin binding
MAG.T21.45_02860	655815.ZPR_1940	5.9e-58	230.3	Flavobacteriia			1.3.99.16	ko:K07302,ko:K07303					ko00000,ko01000				Bacteria	1I17D@117743,4NM72@976,COG2080@1,COG2080@2	NA|NA|NA	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS
MAG.T21.45_02861	1123276.KB893269_gene4784	1.4e-40	172.6	Bacteroidetes													Bacteria	4NR0K@976,COG1917@1,COG1917@2	NA|NA|NA	S	Domain of unknown function (DUF4440)
MAG.T21.45_02862	929703.KE386491_gene3677	1.8e-119	435.6	Cytophagia													Bacteria	47JHN@768503,4NDYY@976,COG2207@1,COG2207@2	NA|NA|NA	K	PFAM helix-turn-helix- domain containing protein AraC type
MAG.T21.45_02863	1239962.C943_04606	1.1e-41	175.6	Cytophagia	higA			ko:K21498					ko00000,ko02048				Bacteria	47R1U@768503,4NSBZ@976,COG3093@1,COG3093@2	NA|NA|NA	K	TIGRFAM addiction module antidote protein, HigA family
MAG.T21.45_02864	1239962.C943_04607	1.2e-34	152.1	Cytophagia				ko:K07334					ko00000,ko02048				Bacteria	47RJA@768503,4NSZ2@976,COG3549@1,COG3549@2	NA|NA|NA	S	PFAM Plasmid maintenance system killer
MAG.T21.45_02865	709991.Odosp_0676	2.5e-15	88.2	Porphyromonadaceae													Bacteria	2319A@171551,2FNA6@200643,4NJS6@976,COG5421@1,COG5421@2	NA|NA|NA	L	PFAM Transposase DDE domain
MAG.T21.45_02866	761193.Runsl_2741	0.0	1713.0	Cytophagia													Bacteria	47M5Q@768503,4NDU8@976,COG1629@1,COG4771@2	NA|NA|NA	P	PFAM TonB-dependent Receptor Plug
MAG.T21.45_02867	761193.Runsl_2742	2.1e-230	805.1	Cytophagia													Bacteria	47MQ9@768503,4PKID@976,COG0521@1,COG0521@2	NA|NA|NA	H	Starch-binding associating with outer membrane
MAG.T21.45_02868	760192.Halhy_6017	1.4e-187	662.5	Sphingobacteriia	pqaA												Bacteria	1IQGJ@117747,4NI0U@976,COG4287@1,COG4287@2	NA|NA|NA	C	PFAM PhoPQ-activated pathogenicity-related protein, PqaA type
MAG.T21.45_02869	761193.Runsl_4623	6.7e-82	311.2	Bacteria				ko:K07052					ko00000				Bacteria	COG1266@1,COG1266@2	NA|NA|NA	V	CAAX protease self-immunity
MAG.T21.45_02870	760192.Halhy_3005	9.1e-23	113.2	Sphingobacteriia													Bacteria	1IU5E@117747,4PGRJ@976,COG0629@1,COG0629@2	NA|NA|NA	L	Domain of unknown function (DUF3127)
MAG.T21.45_02871	760192.Halhy_5787	1.6e-134	485.7	Sphingobacteriia													Bacteria	1IR39@117747,4NFK1@976,COG0189@1,COG0189@2	NA|NA|NA	HJ	Glutathione synthase
MAG.T21.45_02872	929562.Emtol_4070	1.4e-81	309.7	Cytophagia			6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	47NFG@768503,4NGC3@976,COG0518@1,COG0518@2	NA|NA|NA	F	Glutamine amidotransferase class-I
MAG.T21.45_02873	760192.Halhy_2737	1.2e-296	1025.4	Sphingobacteriia	gyrB	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02470					ko00000,ko01000,ko03032,ko03400				Bacteria	1IP1Y@117747,4NE0P@976,COG0187@1,COG0187@2	NA|NA|NA	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MAG.T21.45_02874	525373.HMPREF0766_10543	2.3e-30	138.7	Sphingobacteriia	yjeE		2.7.1.221	ko:K06925,ko:K07102	ko00520,ko01100,map00520,map01100		R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000,ko03016				Bacteria	1ISTA@117747,4NS89@976,COG0802@1,COG0802@2	NA|NA|NA	S	PFAM Uncharacterised protein family UPF0079, ATPase
MAG.T21.45_02875	760192.Halhy_4638	4.6e-253	880.6	Sphingobacteriia				ko:K09955					ko00000				Bacteria	1IRCX@117747,4NFW3@976,COG3533@1,COG3533@2	NA|NA|NA	S	Beta-L-arabinofuranosidase, GH127
MAG.T21.45_02876	760192.Halhy_3696	6.5e-150	537.3	Sphingobacteriia	kynU	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQ2Y@117747,4NECS@976,COG3844@1,COG3844@2	NA|NA|NA	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively
MAG.T21.45_02877	760192.Halhy_3276	0.0	1550.0	Sphingobacteriia	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680		ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4			Bacteria	1IPHM@117747,4NF7C@976,COG0653@1,COG0653@2	NA|NA|NA	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MAG.T21.45_02880	760192.Halhy_3940	2.3e-112	412.1	Sphingobacteriia	terC			ko:K05794					ko00000				Bacteria	1IQW6@117747,4NH7P@976,COG0861@1,COG0861@2	NA|NA|NA	P	Integral membrane protein TerC
MAG.T21.45_02881	760192.Halhy_3939	2.3e-28	132.9	Bacteroidetes													Bacteria	4NPIV@976,COG0589@1,COG0589@2	NA|NA|NA	T	Universal stress protein family
MAG.T21.45_02882	1286632.P278_16270	4.4e-90	337.8	Flavobacteriia	rluF		5.4.99.19,5.4.99.21,5.4.99.22	ko:K06178,ko:K06182,ko:K06183					ko00000,ko01000,ko03009				Bacteria	1HY0B@117743,4NFE1@976,COG1187@1,COG1187@2	NA|NA|NA	J	Belongs to the pseudouridine synthase RsuA family
MAG.T21.45_02883	1392498.JQLH01000001_gene2778	1.4e-226	793.1	Maribacter				ko:K02014					ko00000,ko02000	1.B.14			Bacteria	1HY9Q@117743,2PGHH@252356,4NDX3@976,COG1629@1,COG4771@2	NA|NA|NA	P	TonB dependent receptor
MAG.T21.45_02884	760192.Halhy_3340	3.3e-84	318.9	Sphingobacteriia	nupG	GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009987,GO:0015211,GO:0015212,GO:0015213,GO:0015214,GO:0015553,GO:0015858,GO:0015860,GO:0015861,GO:0015862,GO:0015863,GO:0015864,GO:0015893,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0032238,GO:0034641,GO:0042221,GO:0042493,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046483,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072530,GO:0072531,GO:1901264,GO:1901360,GO:1901505,GO:1901642		ko:K03289,ko:K03301,ko:K08218,ko:K11537	ko01501,map01501	M00628			ko00000,ko00001,ko00002,ko02000	2.A.1.10.1,2.A.1.10.2,2.A.1.25,2.A.12		iECS88_1305.ECS88_2595,iECW_1372.ECW_m2299,iEcSMS35_1347.EcSMS35_3108,iWFL_1372.ECW_m2299	Bacteria	1J0SK@117747,4NE0X@976,COG2211@1,COG2211@2	NA|NA|NA	G	Nucleoside H+ symporter
MAG.T21.45_02885	709991.Odosp_1196	2.3e-81	308.9	Porphyromonadaceae													Bacteria	231VA@171551,2FS1J@200643,4NF6D@976,COG2227@1,COG2227@2	NA|NA|NA	H	Methyltransferase domain protein
MAG.T21.45_02888	215803.DB30_1767	1.1e-72	280.4	Myxococcales	ydhF												Bacteria	1MY3G@1224,2X34H@28221,2YU7T@29,437V0@68525,COG4989@1,COG4989@2	NA|NA|NA	S	Aldo/keto reductase family
MAG.T21.45_02889	760192.Halhy_1490	3.6e-70	271.6	Sphingobacteriia													Bacteria	1IXSV@117747,4NIT2@976,COG0398@1,COG0398@2	NA|NA|NA	S	Protein of unknown function, DUF547
MAG.T21.45_02890	929562.Emtol_2610	2.8e-59	235.0	Cytophagia	mog	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0032324,GO:0034641,GO:0042278,GO:0042802,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.7.7.75,2.8.1.12	ko:K03635,ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122		R09395,R09726	RC00002,RC02507	ko00000,ko00001,ko01000			iAPECO1_1312.APECO1_1969,iECABU_c1320.ECABU_c00100,iECED1_1282.ECED1_0009,iECNA114_1301.ECNA114_4653,iECP_1309.ECP_0010,iECS88_1305.ECS88_0010,iECSF_1327.ECSF_0009,iECUMN_1333.ECUMN_0010,iEcSMS35_1347.EcSMS35_0008,iLF82_1304.LF82_1379,iNRG857_1313.NRG857_00050,iUMN146_1321.UM146_22820	Bacteria	47KA4@768503,4PIS5@976,COG0521@1,COG0521@2	NA|NA|NA	H	Probable molybdopterin binding domain
MAG.T21.45_02891	760192.Halhy_2056	2.9e-255	888.3	Sphingobacteriia	pepN		3.4.11.2,3.5.2.6	ko:K01256,ko:K17836	ko00311,ko00480,ko01100,ko01130,ko01501,map00311,map00480,map01100,map01130,map01501	M00627,M00628	R00899,R04951,R06363	RC00096,RC00141,RC01499	ko00000,ko00001,ko00002,ko01000,ko01002,ko01504				Bacteria	1IRKM@117747,4NGTZ@976,COG0308@1,COG0308@2,COG2367@1,COG2367@2	NA|NA|NA	E	Peptidase M1, membrane alanine aminopeptidase
MAG.T21.45_02892	700598.Niako_1363	6.1e-61	241.1	Bacteroidetes													Bacteria	2DBS0@1,2ZANT@2,4NQP3@976	NA|NA|NA		
MAG.T21.45_02893	760192.Halhy_3152	1.2e-184	652.9	Sphingobacteriia													Bacteria	1IQ0C@117747,4NEFN@976,COG3119@1,COG3119@2	NA|NA|NA	P	Sulfatase
MAG.T21.45_02894	1122605.KB893649_gene3750	1.9e-112	412.9	Sphingobacteriia													Bacteria	1IS5G@117747,4NF1X@976,COG3119@1,COG3119@2	NA|NA|NA	P	Sulfatase
MAG.T21.45_02895	269798.CHU_1297	2.1e-71	276.2	Cytophagia			1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000				Bacteria	47PT4@768503,4NQK0@976,COG0262@1,COG0262@2	NA|NA|NA	H	PFAM RibD C-terminal domain
MAG.T21.45_02896	1185876.BN8_02923	1.9e-39	169.5	Cytophagia													Bacteria	2C25Y@1,3399H@2,47SDB@768503,4NXDI@976	NA|NA|NA		
MAG.T21.45_02898	1218103.CIN01S_07_00750	1.5e-31	142.1	Chryseobacterium				ko:K22299					ko00000,ko03000				Bacteria	1I2V9@117743,3ZSWB@59732,4NQQJ@976,COG1396@1,COG1396@2	NA|NA|NA	K	Helix-turn-helix domain
MAG.T21.45_02899	908937.Prede_1226	2.2e-105	388.7	Bacteroidia			2.1.1.72	ko:K00571					ko00000,ko01000,ko02048				Bacteria	2G31R@200643,4NZ6D@976,COG0863@1,COG0863@2	NA|NA|NA	L	Belongs to the N(4) N(6)-methyltransferase family
MAG.T21.45_02900	443143.GM18_2920	5.2e-43	181.8	Deltaproteobacteria				ko:K07448					ko00000,ko02048				Bacteria	1Q2VY@1224,2WN9Y@28221,42RZI@68525,COG1715@1,COG1715@2	NA|NA|NA	L	Mrr N-terminal domain
MAG.T21.45_02902	397287.C807_03323	2.3e-30	139.0	Firmicutes			2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	1VU5X@1239,COG0286@1,COG0286@2	NA|NA|NA	V	site-specific DNA-methyltransferase (adenine-specific) activity
MAG.T21.45_02903	340177.Cag_0513	8.3e-122	443.4	Bacteria													Bacteria	COG3943@1,COG3943@2	NA|NA|NA		
MAG.T21.45_02904	933262.AXAM01000026_gene3073	1.5e-102	380.2	Deltaproteobacteria													Bacteria	1R4NN@1224,2WM2Z@28221,42NMV@68525,COG1672@1,COG1672@2	NA|NA|NA	S	PFAM Archaeal ATPase
MAG.T21.45_02905	1123248.KB893320_gene3912	1.1e-112	413.7	Sphingobacteriia			5.1.3.11	ko:K16213			R01445,R10810	RC00289	ko00000,ko01000				Bacteria	1IVKJ@117747,4NEH7@976,COG2942@1,COG2942@2	NA|NA|NA	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
MAG.T21.45_02906	760192.Halhy_0192	2.9e-238	831.6	Sphingobacteriia													Bacteria	1IXCR@117747,4NKDS@976,COG1629@1,COG1629@2	NA|NA|NA	P	Carboxypeptidase regulatory-like domain
MAG.T21.45_02907	929556.Solca_1279	4.8e-55	221.1	Sphingobacteriia	yciO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.7.7.87	ko:K07566			R10463	RC00745	ko00000,ko01000,ko03009,ko03016				Bacteria	1IQWM@117747,4NDZR@976,COG0009@1,COG0009@2	NA|NA|NA	J	Belongs to the SUA5 family
MAG.T21.45_02908	760192.Halhy_4602	4.7e-94	353.2	Bacteroidetes													Bacteria	4NTMJ@976,COG3210@1,COG3210@2,COG3591@1,COG3591@2	NA|NA|NA	U	Putative binding domain, N-terminal
MAG.T21.45_02909	1288963.ADIS_2205	4.8e-104	384.4	Cytophagia			3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	47JC9@768503,4NF4A@976,COG3386@1,COG3386@2	NA|NA|NA	G	PFAM SMP-30 Gluconolaconase
MAG.T21.45_02910	1122176.KB903609_gene5256	5.6e-187	660.6	Sphingobacteriia	chlI		6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110		R03877	RC01012	ko00000,ko00001,ko01000			iNJ661.Rv0958	Bacteria	1IQK5@117747,4NF1J@976,COG1239@1,COG1239@2	NA|NA|NA	H	Sigma-54 interaction domain
MAG.T21.45_02911	1122176.KB903587_gene4434	2.4e-75	288.9	Sphingobacteriia			3.4.15.6	ko:K13282			R09722	RC00064,RC00141	ko00000,ko01000,ko01002				Bacteria	1IWDD@117747,4NHDE@976,COG4242@1,COG4242@2	NA|NA|NA	PQ	Peptidase family S51
MAG.T21.45_02912	1048983.EL17_20195	7.5e-58	230.7	Cytophagia	phoA		3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147				Bacteria	47JGJ@768503,4NG3D@976,COG1785@1,COG1785@2	NA|NA|NA	P	Belongs to the alkaline phosphatase family
MAG.T21.45_02913	504472.Slin_5006	9.7e-307	1059.3	Cytophagia			2.4.1.8,3.2.1.51	ko:K00691,ko:K15923	ko00500,ko00511,ko01100,map00500,map00511,map01100		R01555	RC00049	ko00000,ko00001,ko01000		GH65,GH95		Bacteria	47JFT@768503,4NEWW@976,COG1554@1,COG1554@2	NA|NA|NA	G	Glycosyl hydrolase family 65, N-terminal domain
MAG.T21.45_02914	1089547.KB913013_gene1198	1.1e-225	789.6	Cytophagia			3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603		R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000				Bacteria	47NXT@768503,4PKHN@976,COG1501@1,COG1501@2	NA|NA|NA	G	Alpha galactosidase A
MAG.T21.45_02916	946077.W5A_12336	8.6e-20	103.6	Flavobacteriia													Bacteria	1I5J8@117743,2BTXK@1,32P5R@2,4NSMQ@976	NA|NA|NA		
MAG.T21.45_02917	1121929.KB898681_gene2035	1.2e-13	82.0	Gracilibacillus				ko:K07729					ko00000,ko03000				Bacteria	1VEGF@1239,4720G@74385,4HNVM@91061,COG1476@1,COG1476@2	NA|NA|NA	K	Helix-turn-helix XRE-family like proteins
MAG.T21.45_02918	906888.JCM19314_346	1e-21	109.8	Nonlabens	ygdD												Bacteria	1I3ZS@117743,3HKJG@363408,4NS8F@976,COG2363@1,COG2363@2	NA|NA|NA	S	Protein of unknown function (DUF423)
MAG.T21.45_02919	760192.Halhy_4883	1.1e-17	95.5	Sphingobacteriia													Bacteria	1IUFE@117747,2ACEV@1,3120D@2,4PGV7@976	NA|NA|NA		
MAG.T21.45_02920	760192.Halhy_4882	7.8e-60	236.9	Sphingobacteriia	yozB			ko:K07152,ko:K08976					ko00000,ko03029				Bacteria	1ISYD@117747,4NM5N@976,COG2322@1,COG2322@2	NA|NA|NA	S	Protein of unknown function (DUF420)
MAG.T21.45_02922	1122179.KB890435_gene911	1.9e-23	115.5	Sphingobacteriia	coxQ												Bacteria	1IU6V@117747,4PGS2@976,COG5605@1,COG5605@2	NA|NA|NA	S	Prokaryotic Cytochrome C oxidase subunit IV
MAG.T21.45_02923	760192.Halhy_4879	2e-118	432.2	Sphingobacteriia	coxP		1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6			Bacteria	1INPX@117747,4NDYG@976,COG1845@1,COG1845@2	NA|NA|NA	C	oxidase subunit III
MAG.T21.45_02924	760192.Halhy_4878	1.7e-54	219.2	Sphingobacteriia	ctaE		1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6			Bacteria	1IST1@117747,4NFA7@976,COG1845@1,COG1845@2	NA|NA|NA	C	cytochrome c oxidase subunit III
MAG.T21.45_02925	760192.Halhy_4877	2.7e-70	272.3	Sphingobacteriia	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029				Bacteria	1IRUR@117747,4NF5A@976,COG0109@1,COG0109@2	NA|NA|NA	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MAG.T21.45_02926	760192.Halhy_4876	0.0	1080.1	Sphingobacteriia	coxN		1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6			Bacteria	1IPZE@117747,4NEH8@976,COG0843@1,COG0843@2	NA|NA|NA	C	Belongs to the heme-copper respiratory oxidase family
MAG.T21.45_02927	760192.Halhy_4875	1e-143	516.9	Sphingobacteriia	coxM	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6			Bacteria	1IPEE@117747,4NFNF@976,COG1622@1,COG1622@2,COG2885@1,COG2885@2	NA|NA|NA	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MAG.T21.45_02928	760192.Halhy_4874	2.9e-163	581.6	Sphingobacteriia	actF												Bacteria	1IPBN@117747,4NF0R@976,COG4531@1,COG4531@2	NA|NA|NA	P	Quinol cytochrome c oxidoreductase
MAG.T21.45_02929	760192.Halhy_4873	4e-81	308.1	Sphingobacteriia	actE												Bacteria	1IRVN@117747,4NKQI@976,COG2010@1,COG2010@2	NA|NA|NA	C	cytochrome C
MAG.T21.45_02930	1122176.KB903531_gene2801	4.7e-67	260.8	Sphingobacteriia	actD												Bacteria	1ITKW@117747,4NEX9@976,COG2010@1,COG2010@2	NA|NA|NA	C	Quinol cytochrome c oxidoreductase
MAG.T21.45_02931	760192.Halhy_4871	1.8e-243	848.2	Sphingobacteriia	actC			ko:K00185					ko00000	5.A.3			Bacteria	1INKZ@117747,4NE3X@976,COG5557@1,COG5557@2	NA|NA|NA	C	PFAM Polysulphide reductase, NrfD
MAG.T21.45_02932	760192.Halhy_4870	0.0	1526.1	Sphingobacteriia	actB			ko:K00184					ko00000	5.A.3			Bacteria	1IPWZ@117747,4NE5M@976,COG0243@1,COG0243@2,COG0437@1,COG0437@2	NA|NA|NA	C	Oxidoreductase
MAG.T21.45_02933	1122176.KB903531_gene2804	2.4e-169	602.1	Sphingobacteriia	psbV	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797		ko:K02720	ko00195,ko01100,map00195,map01100				ko00000,ko00001,ko00194			iJN678.psbV	Bacteria	1IPBV@117747,4NF0A@976,COG2010@1,COG2010@2	NA|NA|NA	C	PFAM Cytochrome c, class I
MAG.T21.45_02934	1122176.KB903531_gene2805	2.5e-121	441.8	Sphingobacteriia	thyA		2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000				Bacteria	1IRAS@117747,4NEC2@976,COG0207@1,COG0207@2	NA|NA|NA	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MAG.T21.45_02935	760192.Halhy_1186	4.2e-109	401.7	Sphingobacteriia	hipO			ko:K01436,ko:K12941					ko00000,ko01000,ko01002				Bacteria	1IVTA@117747,4NGBI@976,COG1473@1,COG1473@2	NA|NA|NA	S	COGs COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MAG.T21.45_02936	1124780.ANNU01000016_gene1861	2.1e-08	65.9	Cytophagia													Bacteria	2AE6H@1,3140B@2,47RV6@768503,4NSDV@976	NA|NA|NA		
MAG.T21.45_02937	1122176.KB903532_gene2515	1.8e-156	559.3	Sphingobacteriia	gabD		1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQTP@117747,4NEB7@976,COG1012@1,COG1012@2	NA|NA|NA	C	Belongs to the aldehyde dehydrogenase family
MAG.T21.45_02938	1004785.AMBLS11_15865	2e-62	246.1	Alteromonadaceae													Bacteria	1R48K@1224,1SAGZ@1236,469XF@72275,COG3000@1,COG3000@2	NA|NA|NA	I	Fatty acid hydroxylase superfamily
MAG.T21.45_02939	760192.Halhy_5708	1e-171	610.5	Sphingobacteriia			1.11.1.7	ko:K19511,ko:K20276	ko02024,map02024				ko00000,ko00001,ko01000				Bacteria	1IYME@117747,4NFV5@976,COG2931@1,COG2931@2	NA|NA|NA	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
MAG.T21.45_02940	1122179.KB890497_gene2758	2.5e-59	235.3	Bacteroidetes	ctaE		1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6			Bacteria	4NU0C@976,COG1845@1,COG1845@2	NA|NA|NA	C	heme copper-type cytochrome quinol oxidase, subunit 3
MAG.T21.45_02941	760192.Halhy_5196	0.0	1137.1	Sphingobacteriia	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000				Bacteria	1IR8F@117747,4NETY@976,COG0046@1,COG0046@2	NA|NA|NA	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MAG.T21.45_02942	760192.Halhy_5195	4.1e-105	388.3	Bacteroidetes													Bacteria	4NEX3@976,COG0526@1,COG0526@2	NA|NA|NA	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MAG.T21.45_02943	760192.Halhy_2156	3.2e-290	1003.8	Sphingobacteriia													Bacteria	1IPAY@117747,4NEHP@976,COG2303@1,COG2303@2	NA|NA|NA	E	Oxidoreductase
MAG.T21.45_02944	760192.Halhy_2155	1.5e-69	269.2	Sphingobacteriia													Bacteria	1ISGE@117747,2CISN@1,2Z7MB@2,4NFJX@976	NA|NA|NA	S	Gluconate 2-dehydrogenase subunit 3
MAG.T21.45_02945	1380600.AUYN01000006_gene770	1.2e-299	1035.4	Flavobacteriia	rhaD		1.1.1.1,4.1.2.19	ko:K00001,ko:K01629	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220		R00623,R00754,R01785,R02124,R02263,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00438,RC00599,RC00603,RC00604,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000				Bacteria	1HXU6@117743,4NEM0@976,COG1028@1,COG1028@2,COG3347@1,COG3347@2	NA|NA|NA	IQ	short-chain dehydrogenase
MAG.T21.45_02946	926556.Echvi_1573	3.8e-163	581.3	Cytophagia	rhaI		5.3.1.14	ko:K01820	ko00040,ko00051,ko01120,map00040,map00051,map01120		R01906,R02437,R06589	RC00376,RC00434,RC00516	ko00000,ko00001,ko01000				Bacteria	47KMM@768503,4NFWW@976,COG4952@1,COG4952@2	NA|NA|NA	M	TIGRFAM L-rhamnose catabolism isomerase, Pseudomonas stutzeri subtype
MAG.T21.45_02947	1121285.AUFK01000009_gene1135	4.5e-111	408.3	Chryseobacterium	fucK		2.7.1.189	ko:K11216	ko02024,map02024		R11183	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	1HYQ6@117743,3ZPFQ@59732,4NE3S@976,COG1070@1,COG1070@2	NA|NA|NA	G	FGGY family of carbohydrate kinases, N-terminal domain
MAG.T21.45_02948	1166018.FAES_4381	6.7e-77	293.9	Cytophagia	lutA			ko:K18928					ko00000				Bacteria	47KGV@768503,4NIMP@976,COG0247@1,COG0247@2	NA|NA|NA	C	Fe-S oxidoreductase
MAG.T21.45_02949	1121904.ARBP01000002_gene7044	4.5e-170	604.4	Cytophagia	lldF			ko:K18929					ko00000				Bacteria	47K0Z@768503,4NEBT@976,COG1139@1,COG1139@2	NA|NA|NA	C	LUD domain
MAG.T21.45_02950	1121957.ATVL01000009_gene869	2.4e-35	155.6	Cytophagia	lldG			ko:K00782					ko00000				Bacteria	47QGX@768503,4NQSF@976,COG1556@1,COG1556@2	NA|NA|NA	S	LUD domain
MAG.T21.45_02951	1121904.ARBP01000005_gene4749	5.6e-176	624.0	Cytophagia				ko:K03457					ko00000	2.A.39			Bacteria	47KQF@768503,4NHHC@976,COG1457@1,COG1457@2	NA|NA|NA	F	Belongs to the purine-cytosine permease (2.A.39) family
MAG.T21.45_02953	517418.Ctha_2168	1.4e-37	163.7	Bacteria													Bacteria	2DZSH@1,32VHS@2	NA|NA|NA	S	to other proteins from the same organism
MAG.T21.45_02954	1034807.FBFL15_0522	7.1e-58	230.7	Bacteroidetes													Bacteria	2DZSH@1,32VHS@2,4NYRA@976	NA|NA|NA	S	to other proteins from the same organism
MAG.T21.45_02955	880071.Fleli_2816	1.4e-63	249.6	Bacteroidetes													Bacteria	28WYZ@1,2ZIXZ@2,4NR8Y@976	NA|NA|NA		
MAG.T21.45_02956	880071.Fleli_2815	2.3e-87	329.3	Bacteroidetes													Bacteria	4NS4E@976,COG4637@1,COG4637@2	NA|NA|NA	S	AAA domain, putative AbiEii toxin, Type IV TA system
MAG.T21.45_02957	880070.Cycma_0604	6.3e-262	909.8	Cytophagia	XK27_08510			ko:K06919					ko00000				Bacteria	47TY1@768503,4NI8N@976,COG1061@1,COG1061@2,COG4951@1,COG4951@2	NA|NA|NA	L	Type III restriction enzyme, res subunit
MAG.T21.45_02958	880070.Cycma_0604	8.4e-136	490.0	Cytophagia	XK27_08510			ko:K06919					ko00000				Bacteria	47TY1@768503,4NI8N@976,COG1061@1,COG1061@2,COG4951@1,COG4951@2	NA|NA|NA	L	Type III restriction enzyme, res subunit
MAG.T21.45_02959	1168034.FH5T_10425	3.4e-36	157.5	Bacteroidia	mazF			ko:K07171					ko00000,ko01000,ko02048				Bacteria	2FU6W@200643,4NQA9@976,COG2337@1,COG2337@2	NA|NA|NA	L	Toxic component of a toxin-antitoxin (TA) module
MAG.T21.45_02960	1124780.ANNU01000044_gene479	9.8e-28	129.0	Cytophagia	mazE			ko:K07172,ko:K18842					ko00000,ko02048				Bacteria	47SRJ@768503,4NSWY@976,COG2336@1,COG2336@2	NA|NA|NA	T	SpoVT / AbrB like domain
MAG.T21.45_02961	1122176.KB903554_gene3990	9.9e-50	203.4	Sphingobacteriia	yceI												Bacteria	1IT7F@117747,4NMWH@976,COG2353@1,COG2353@2	NA|NA|NA	S	Belongs to the UPF0312 family
MAG.T21.45_02962	760192.Halhy_5048	1.8e-33	149.1	Sphingobacteriia													Bacteria	1IT21@117747,4NQ5T@976,COG1846@1,COG1846@2	NA|NA|NA	K	Transcriptional regulator
MAG.T21.45_02963	760192.Halhy_5049	3.2e-102	378.3	Sphingobacteriia	proC	GO:0003674,GO:0003824,GO:0004735,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000				Bacteria	1IXBC@117747,4NGIG@976,COG0345@1,COG0345@2	NA|NA|NA	E	Pyrroline-5-carboxylate reductase dimerisation
MAG.T21.45_02964	760192.Halhy_5050	9.9e-106	390.6	Sphingobacteriia	rmuC			ko:K09760					ko00000				Bacteria	1INWB@117747,4NE04@976,COG1322@1,COG1322@2	NA|NA|NA	S	PFAM RmuC family
MAG.T21.45_02965	1089547.KB913013_gene770	2e-86	325.9	Cytophagia													Bacteria	47JA9@768503,4NFMD@976,COG1082@1,COG1082@2	NA|NA|NA	G	Xylose isomerase domain protein TIM barrel
MAG.T21.45_02966	760192.Halhy_3104	1e-243	849.4	Sphingobacteriia													Bacteria	1IQH0@117747,4NEF2@976,COG2303@1,COG2303@2	NA|NA|NA	E	Oxidoreductase
MAG.T21.45_02967	760192.Halhy_1071	7.3e-17	94.0	Bacteroidetes													Bacteria	2CDAN@1,309X8@2,4NRN2@976	NA|NA|NA	S	Gluconate 2-dehydrogenase subunit 3
MAG.T21.45_02968	760192.Halhy_0297	2e-294	1018.5	Sphingobacteriia													Bacteria	1IQMT@117747,4NFP6@976,COG2010@1,COG2010@2	NA|NA|NA	C	Protein of unknown function (DUF1553)
MAG.T21.45_02969	760192.Halhy_0298	8e-229	799.7	Sphingobacteriia													Bacteria	1INVW@117747,4PN6J@976,COG4102@1,COG4102@2	NA|NA|NA	S	Protein of unknown function (DUF1501)
MAG.T21.45_02970	760192.Halhy_0299	2.4e-103	382.1	Sphingobacteriia													Bacteria	1INZG@117747,4NFEA@976,COG1082@1,COG1082@2	NA|NA|NA	G	Pfam Xylose
MAG.T21.45_02971	929713.NIASO_15835	4.9e-52	212.2	Sphingobacteriia													Bacteria	1IPVN@117747,4NFES@976,COG4886@1,COG4886@2	NA|NA|NA	S	Planctomycete cytochrome C
MAG.T21.45_02972	760192.Halhy_3998	1.2e-255	889.0	Sphingobacteriia			2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100		R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002				Bacteria	1IPXR@117747,4NG3X@976,COG0405@1,COG0405@2	NA|NA|NA	E	Gamma-glutamyltranspeptidase
MAG.T21.45_02973	700598.Niako_5153	1.7e-122	446.0	Sphingobacteriia	xdhC												Bacteria	1IQT3@117747,4NG02@976,COG1975@1,COG1975@2	NA|NA|NA	O	COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family
MAG.T21.45_02974	760192.Halhy_6121	2.9e-156	558.1	Sphingobacteriia	fabH		2.3.1.180,2.3.1.262	ko:K00648,ko:K18003	ko00061,ko00405,ko01100,ko01130,ko01212,ko02024,ko02025,map00061,map00405,map01100,map01130,map01212,map02024,map02025	M00082,M00083	R10707,R11586,R11587,R11588	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1IRA1@117747,4NFIN@976,COG0332@1,COG0332@2	NA|NA|NA	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MAG.T21.45_02975	760192.Halhy_6043	6.6e-213	747.3	Sphingobacteriia	recQ	GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008270,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0017117,GO:0030894,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033202,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043142,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1904949	3.6.4.12	ko:K03654	ko03018,map03018				ko00000,ko00001,ko01000,ko03400				Bacteria	1IQU0@117747,4NG10@976,COG0514@1,COG0514@2	NA|NA|NA	L	RQC
MAG.T21.45_02976	760192.Halhy_6029	8.4e-77	293.9	Sphingobacteriia	glpQ		3.1.4.46	ko:K01126	ko00564,map00564		R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000				Bacteria	1ISHR@117747,4NGI1@976,COG0584@1,COG0584@2	NA|NA|NA	C	PFAM Glycerophosphoryl diester phosphodiesterase
MAG.T21.45_02977	760192.Halhy_6028	2.8e-130	472.6	Sphingobacteriia	prcA												Bacteria	1IWKE@117747,4NF1M@976,COG1404@1,COG1404@2	NA|NA|NA	O	Subtilase family
MAG.T21.45_02978	760192.Halhy_1605	0.0	1327.0	Sphingobacteriia													Bacteria	1IVPS@117747,4NESU@976,COG4447@1,COG4447@2	NA|NA|NA	M	Sortilin, neurotensin receptor 3,
MAG.T21.45_02979	1122176.KB903541_gene252	1.2e-33	150.2	Sphingobacteriia	waaM		2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1IRHE@117747,4NGQU@976,COG1560@1,COG1560@2	NA|NA|NA	M	PFAM Bacterial lipid A biosynthesis acyltransferase
MAG.T21.45_02980	760192.Halhy_6398	1.8e-182	647.1	Bacteria	pal			ko:K03640					ko00000,ko02000	2.C.1.2			Bacteria	COG2885@1,COG2885@2,COG3292@1,COG3292@2	NA|NA|NA	M	chlorophyll binding
MAG.T21.45_02981	760192.Halhy_0169	0.0	1457.2	Bacteroidetes													Bacteria	4NJFX@976,COG4447@1,COG4447@2	NA|NA|NA	S	Sortilin, neurotensin receptor 3,
MAG.T21.45_02983	760192.Halhy_0286	4.3e-125	454.5	Sphingobacteriia	selD	GO:0000287,GO:0001887,GO:0003674,GO:0003824,GO:0004756,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009451,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019752,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0070329,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100		R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016			iPC815.YPO2164,iSFV_1184.SFV_1453,iSF_1195.SF1459,iSFxv_1172.SFxv_1645,iS_1188.S1574	Bacteria	1INUS@117747,4NI4R@976,COG0709@1,COG0709@2	NA|NA|NA	E	Synthesizes selenophosphate from selenide and ATP
MAG.T21.45_02984	760192.Halhy_0287	7.2e-99	367.5	Sphingobacteriia	selU	GO:0001887,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016785,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043828,GO:0044237,GO:0044238,GO:0046483,GO:0070329,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360		ko:K06917					ko00000,ko01000,ko03016				Bacteria	1IRWP@117747,4NH7W@976,COG2603@1,COG2603@2	NA|NA|NA	S	Rhodanese Homology Domain
MAG.T21.45_02985	1122179.KB890455_gene3031	2.7e-119	435.3	Sphingobacteriia													Bacteria	1IU4R@117747,4NEYE@976,COG3000@1,COG3000@2	NA|NA|NA	I	Fatty acid hydroxylase superfamily
MAG.T21.45_02986	760192.Halhy_5953	1.5e-206	725.7	Sphingobacteriia													Bacteria	1IQVW@117747,4NEGK@976,COG0535@1,COG0535@2	NA|NA|NA	S	radical SAM domain protein
MAG.T21.45_02987	760192.Halhy_5952	8.2e-173	613.2	Sphingobacteriia	leuA	GO:0003674,GO:0003824,GO:0003852,GO:0003985,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046912,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000			iSFV_1184.SFV_0066	Bacteria	1INXS@117747,4NEIT@976,COG0119@1,COG0119@2	NA|NA|NA	E	Belongs to the alpha-IPM synthase homocitrate synthase family
MAG.T21.45_02988	926549.KI421517_gene739	8.8e-198	696.4	Cytophagia	leuC	GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000			iEcE24377_1341.EcE24377A_0075,iPC815.YPO0531,iSB619.SA_RS10700	Bacteria	47JAE@768503,4NG7E@976,COG0065@1,COG0065@2	NA|NA|NA	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MAG.T21.45_02989	1121904.ARBP01000015_gene237	2.2e-76	292.0	Cytophagia	leuD		4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	47NNG@768503,4NDVY@976,COG0066@1,COG0066@2	NA|NA|NA	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MAG.T21.45_02990	929556.Solca_4146	1.2e-135	489.6	Sphingobacteriia	leuB		1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1INYR@117747,4NEBE@976,COG0473@1,COG0473@2	NA|NA|NA	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MAG.T21.45_02991	1122176.KB903536_gene1811	2.2e-181	641.7	Sphingobacteriia	mqnE	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188	2.5.1.120,2.5.1.77	ko:K11779,ko:K11780,ko:K11781,ko:K18285	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R09396,R10667	RC00021,RC01381,RC03002,RC03007,RC03234	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_3391	Bacteria	1IPM7@117747,4NGDN@976,COG1060@1,COG1060@2	NA|NA|NA	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
MAG.T21.45_02992	760192.Halhy_5957	1.9e-54	219.2	Sphingobacteriia	gpm		5.4.2.11,5.4.2.12	ko:K01834,ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147				Bacteria	1IS36@117747,4NFX5@976,COG0406@1,COG0406@2	NA|NA|NA	G	phosphoglycerate mutase family
MAG.T21.45_02993	760192.Halhy_5956	8.3e-68	263.8	Sphingobacteriia	mqnA		1.21.98.1,4.2.1.151	ko:K07081,ko:K11782,ko:K11784	ko00130,ko01110,map00130,map01110		R08588,R10666	RC02329,RC03232	ko00000,ko00001,ko01000				Bacteria	1ISCN@117747,4NN4W@976,COG1427@1,COG1427@2	NA|NA|NA	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
MAG.T21.45_02994	760192.Halhy_5955	3e-53	214.9	Sphingobacteriia	msrA		1.8.4.11,1.8.4.12	ko:K07304,ko:K12267					ko00000,ko01000				Bacteria	1IXAW@117747,4NMAJ@976,COG0225@1,COG0225@2	NA|NA|NA	O	Peptide methionine sulfoxide reductase
MAG.T21.45_02995	1121904.ARBP01000010_gene2238	4.1e-110	404.8	Cytophagia	pntA	GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0097159,GO:1901265,GO:1901363	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100		R00112	RC00001	ko00000,ko00001,ko01000				Bacteria	47KX8@768503,4NGH1@976,COG3288@1,COG3288@2	NA|NA|NA	C	Alanine dehydrogenase/PNT, C-terminal domain
MAG.T21.45_02996	1121904.ARBP01000010_gene2239	3.3e-28	131.0	Cytophagia	pntAA		1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100		R00112	RC00001	ko00000,ko00001,ko01000				Bacteria	47RF1@768503,4NT78@976,COG3288@1,COG3288@2	NA|NA|NA	C	4TM region of pyridine nucleotide transhydrogenase, mitoch
MAG.T21.45_02997	1122176.KB903543_gene574	1.1e-155	556.6	Sphingobacteriia	pntB		1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100		R00112	RC00001	ko00000,ko00001,ko01000				Bacteria	1IPVT@117747,4NHGZ@976,COG1282@1,COG1282@2	NA|NA|NA	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MAG.T21.45_02998	760192.Halhy_0751	3.7e-115	421.4	Sphingobacteriia	XK27_08050												Bacteria	1IQTZ@117747,4NEP5@976,COG0330@1,COG0330@2	NA|NA|NA	O	COG0330 Membrane protease subunits stomatin prohibitin homologs
MAG.T21.45_02999	643867.Ftrac_2650	5.7e-264	917.1	Cytophagia													Bacteria	47JCM@768503,4NEA0@976,COG5549@1,COG5549@2	NA|NA|NA	O	Domain of unknown function (DUF5118)
MAG.T21.45_03000	983544.Lacal_2514	1.8e-17	96.3	Flavobacteriia	phaD												Bacteria	1II5D@117743,4NN5I@976,COG1309@1,COG1309@2	NA|NA|NA	K	Bacterial transcriptional repressor
MAG.T21.45_03001	760192.Halhy_4269	1.4e-166	592.8	Sphingobacteriia													Bacteria	1IVP1@117747,4NFUP@976,COG0076@1,COG0076@2	NA|NA|NA	E	COGs COG0076 Glutamate decarboxylase and related PLP-dependent protein
MAG.T21.45_03002	1122176.KB903534_gene2206	2e-155	555.4	Sphingobacteriia	mnmA		2.8.1.13	ko:K00566	ko04122,map04122		R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016				Bacteria	1IR3X@117747,4NFXZ@976,COG0482@1,COG0482@2	NA|NA|NA	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MAG.T21.45_03003	1122176.KB903534_gene2204	2.9e-29	135.2	Sphingobacteriia	rimM	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360		ko:K02860					ko00000,ko03009				Bacteria	1ISWU@117747,4NQF0@976,COG0806@1,COG0806@2	NA|NA|NA	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MAG.T21.45_03004	760192.Halhy_5758	2.9e-245	854.4	Sphingobacteriia			3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000				Bacteria	1IR48@117747,4NG0U@976,COG1228@1,COG1228@2	NA|NA|NA	Q	Amidohydrolase family
MAG.T21.45_03005	760192.Halhy_5966	8.4e-21	107.5	Sphingobacteriia													Bacteria	1IS8G@117747,4NQ2C@976,COG1280@1,COG1280@2	NA|NA|NA	E	Lysine exporter protein (LYSE YGGA)
MAG.T21.45_03006	1313421.JHBV01000016_gene5396	2.8e-29	136.0	Sphingobacteriia	rlpA			ko:K02451,ko:K03642		M00331			ko00000,ko00002,ko02044	9.B.42			Bacteria	1ITKY@117747,4NSF1@976,COG0797@1,COG0797@2,COG3266@1,COG3266@2	NA|NA|NA	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MAG.T21.45_03007	760192.Halhy_5424	5e-39	167.5	Bacteria													Bacteria	COG4886@1,COG4886@2	NA|NA|NA	S	regulation of response to stimulus
MAG.T21.45_03008	760192.Halhy_0097	1.5e-243	849.0	Sphingobacteriia	yheS			ko:K06158					ko00000,ko03012				Bacteria	1IPB4@117747,4NG1W@976,COG0488@1,COG0488@2	NA|NA|NA	S	ABC transporter
MAG.T21.45_03009	760192.Halhy_0096	3.9e-113	414.8	Sphingobacteriia	phoR		2.7.13.3	ko:K07636	ko02020,map02020	M00434			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	1IQ3E@117747,4NETP@976,COG5002@1,COG5002@2	NA|NA|NA	T	Histidine kinase
MAG.T21.45_03010	1122176.KB903532_gene2614	1.3e-82	312.8	Sphingobacteriia													Bacteria	1IPM8@117747,4NG7D@976,COG0745@1,COG0745@2	NA|NA|NA	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MAG.T21.45_03012	1499967.BAYZ01000111_gene2960	2.6e-19	102.1	Bacteria	sixA			ko:K08296					ko00000,ko01000				Bacteria	COG2062@1,COG2062@2	NA|NA|NA	T	phosphohistidine phosphatase, SixA
MAG.T21.45_03013	1122176.KB903553_gene3621	2.3e-132	479.2	Sphingobacteriia				ko:K03671	ko04621,ko05418,map04621,map05418				ko00000,ko00001,ko03110				Bacteria	1IXCQ@117747,4NHEC@976,COG0526@1,COG0526@2	NA|NA|NA	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MAG.T21.45_03014	1122176.KB903554_gene3940	4.3e-132	477.6	Sphingobacteriia	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00608,ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000			iYO844.BSU15490	Bacteria	1IP8Y@117747,4NFIU@976,COG0540@1,COG0540@2	NA|NA|NA	F	Belongs to the ATCase OTCase family
MAG.T21.45_03015	1122176.KB903554_gene3941	9.9e-55	219.9	Sphingobacteriia	pyrR	GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100		R00966	RC00063	ko00000,ko00001,ko01000,ko03000				Bacteria	1IQWE@117747,4NFI1@976,COG2065@1,COG2065@2	NA|NA|NA	F	uracil phosphoribosyltransferase
MAG.T21.45_03016	760192.Halhy_0990	3.4e-228	797.7	Sphingobacteriia	glnS	GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iECIAI39_1322.ECIAI39_0637	Bacteria	1IQC9@117747,4NFCC@976,COG0008@1,COG0008@2	NA|NA|NA	J	Glutaminyl-tRNA synthetase
MAG.T21.45_03017	760192.Halhy_0989	2.3e-217	761.9	Sphingobacteriia	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	1IQGR@117747,4NE7Q@976,COG0018@1,COG0018@2	NA|NA|NA	J	Arginyl-tRNA synthetase
MAG.T21.45_03018	760192.Halhy_0987	2e-65	255.4	Sphingobacteriia	rsmD		2.1.1.171	ko:K08316,ko:K15257			R07234	RC00003	ko00000,ko01000,ko03009,ko03016				Bacteria	1ISB1@117747,4NM7J@976,COG0742@1,COG0742@2	NA|NA|NA	L	RNA methyltransferase, RsmD
MAG.T21.45_03019	762984.HMPREF9445_02898	1.3e-10	73.9	Bacteroidaceae													Bacteria	2DNC5@1,2G3AT@200643,32WQD@2,4AWCR@815,4NU4Q@976	NA|NA|NA	S	Psort location Cytoplasmic, score 8.96
MAG.T21.45_03020	1168289.AJKI01000042_gene3718	4.3e-13	81.6	Marinilabiliaceae													Bacteria	2C0G9@1,2FN0C@200643,310GM@2,3XIJG@558415,4NHU0@976	NA|NA|NA	S	COG NOG19144 non supervised orthologous group
MAG.T21.45_03021	760192.Halhy_0984	8.8e-118	430.3	Sphingobacteriia	tsaD	GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	R10648	RC00070,RC00416	ko00000,ko00001,ko00002,ko01000,ko02044,ko03016	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4			Bacteria	1INZZ@117747,4NE8E@976,COG0533@1,COG0533@2	NA|NA|NA	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MAG.T21.45_03022	760192.Halhy_5628	2.9e-64	251.9	Bacteroidetes													Bacteria	4NSI8@976,COG3597@1,COG3597@2	NA|NA|NA	S	Domain of unknown function (DUF697)
MAG.T21.45_03023	760192.Halhy_5215	0.0	1099.3	Sphingobacteriia													Bacteria	1IQPG@117747,4NED2@976,COG2373@1,COG2373@2	NA|NA|NA	S	COG2373 Large extracellular alpha-helical protein
MAG.T21.45_03024	760192.Halhy_5216	9e-78	297.4	Sphingobacteriia	mnmC	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363	2.1.1.61	ko:K15461			R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016				Bacteria	1IXHP@117747,4NFCD@976,COG0665@1,COG0665@2	NA|NA|NA	E	FAD dependent oxidoreductase
MAG.T21.45_03025	509635.N824_26705	1.2e-39	170.2	Bacteria													Bacteria	2DNH9@1,32XHM@2	NA|NA|NA		
MAG.T21.45_03026	760192.Halhy_1315	6.6e-53	214.5	Bacteroidetes													Bacteria	2FG80@1,3484C@2,4P5E2@976	NA|NA|NA		
MAG.T21.45_03027	760192.Halhy_1314	2.7e-165	588.6	Sphingobacteriia	wcaJ	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016780,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046402,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.187,2.7.8.40	ko:K05946,ko:K21303	ko05111,map05111				ko00000,ko00001,ko01000,ko01003,ko01005		GT26		Bacteria	1IS31@117747,4NFIA@976,COG1086@1,COG1086@2,COG2148@1,COG2148@2	NA|NA|NA	M	Bacterial sugar transferase
MAG.T21.45_03028	1121286.AUMT01000025_gene2539	8.6e-24	118.6	Bacteria													Bacteria	COG5295@1,COG5295@2	NA|NA|NA	UW	Hep Hag repeat protein
MAG.T21.45_03030	945713.IALB_0186	1.4e-15	90.9	Bacteria			3.4.24.40	ko:K01406,ko:K21449	ko01503,map01503				ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2			Bacteria	COG4675@1,COG4675@2,COG5276@1,COG5276@2	NA|NA|NA	M	tail collar domain protein
MAG.T21.45_03031	945713.IALB_0186	2.1e-14	87.0	Bacteria			3.4.24.40	ko:K01406,ko:K21449	ko01503,map01503				ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2			Bacteria	COG4675@1,COG4675@2,COG5276@1,COG5276@2	NA|NA|NA	M	tail collar domain protein
MAG.T21.45_03032	945713.IALB_0186	9.6e-10	71.6	Bacteria			3.4.24.40	ko:K01406,ko:K21449	ko01503,map01503				ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2			Bacteria	COG4675@1,COG4675@2,COG5276@1,COG5276@2	NA|NA|NA	M	tail collar domain protein
MAG.T21.45_03033	1122176.KB903554_gene4015	3.3e-191	674.5	Sphingobacteriia	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000				Bacteria	1INXM@117747,4NG7Y@976,COG0192@1,COG0192@2	NA|NA|NA	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MAG.T21.45_03034	760192.Halhy_4476	1.4e-78	299.3	Sphingobacteriia	ycgM												Bacteria	1INU6@117747,4NGCT@976,COG0179@1,COG0179@2	NA|NA|NA	Q	PFAM fumarylacetoacetate (FAA) hydrolase
MAG.T21.45_03035	1313421.JHBV01000019_gene5381	1e-126	459.9	Sphingobacteriia	trpS		6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1INYI@117747,4NETX@976,COG0180@1,COG0180@2	NA|NA|NA	J	Tryptophanyl-tRNA synthetase
MAG.T21.45_03036	1341155.FSS13T_18060	2.3e-39	168.3	Flavobacterium	tdcF		3.5.99.10	ko:K09022			R11098,R11099	RC03275,RC03354	ko00000,ko01000				Bacteria	1I2YH@117743,2NWBM@237,4NQ8M@976,COG0251@1,COG0251@2	NA|NA|NA	J	Endoribonuclease L-PSP
MAG.T21.45_03037	1122176.KB903587_gene4528	4.7e-17	93.2	Sphingobacteriia	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904		ko:K02911	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011,ko03029				Bacteria	1IU0H@117747,4NUXU@976,COG0333@1,COG0333@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL32 family
MAG.T21.45_03038	1122176.KB903587_gene4529	1.4e-29	136.3	Sphingobacteriia	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464		ko:K07040					ko00000				Bacteria	1ISWG@117747,4NMQT@976,COG1399@1,COG1399@2	NA|NA|NA	S	acr, cog1399
MAG.T21.45_03039	1122176.KB903531_gene3070	1.2e-15	90.9	Bacteria			2.7.7.7,5.4.99.21	ko:K02343,ko:K06182,ko:K08372,ko:K12065,ko:K16291	ko00230,ko00240,ko01100,ko02020,ko03030,ko03430,ko03440,map00230,map00240,map01100,map02020,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02044,ko03009,ko03032,ko03400	3.A.7.11.1			Bacteria	COG3087@1,COG3087@2	NA|NA|NA	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MAG.T21.45_03040	760192.Halhy_4539	4.5e-175	620.9	Sphingobacteriia	hemL	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007			iSB619.SA_RS08395,iUMNK88_1353.UMNK88_158	Bacteria	1INWD@117747,4NDXG@976,COG0001@1,COG0001@2	NA|NA|NA	H	Glutamate-1-semialdehyde aminotransferase
MAG.T21.45_03041	760192.Halhy_4538	1.1e-90	340.1	Sphingobacteriia													Bacteria	1IPNM@117747,4NK58@976,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
MAG.T21.45_03042	760192.Halhy_4537	2.1e-99	368.6	Sphingobacteriia													Bacteria	1INQ4@117747,4NGXP@976,COG0745@1,COG0745@2	NA|NA|NA	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MAG.T21.45_03043	760192.Halhy_3877	6.6e-256	890.2	Sphingobacteriia	otsB	GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0046872,GO:0050896,GO:0051716,GO:0070413,GO:0070415,GO:0070417,GO:0071704,GO:1901576	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K01087,ko:K16055	ko00500,ko01100,map00500,map01100		R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003		GT20	iE2348C_1286.E2348C_2018,iECED1_1282.ECED1_2163,iECIAI39_1322.ECIAI39_1155,iECS88_1305.ECS88_1952,iLF82_1304.LF82_1582,iNRG857_1313.NRG857_09495	Bacteria	1IPE7@117747,4NGJ4@976,COG0380@1,COG0380@2,COG1877@1,COG1877@2	NA|NA|NA	G	HAD-superfamily hydrolase, subfamily IIB
MAG.T21.45_03045	760192.Halhy_3879	1.3e-44	186.0	Sphingobacteriia	rpsP	GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02959	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011,ko03029				Bacteria	1IRXR@117747,4NNY8@976,COG0228@1,COG0228@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bS16 family
MAG.T21.45_03046	760192.Halhy_1843	0.0	1140.9	Sphingobacteriia													Bacteria	1J0WW@117747,4NFFN@976,COG1629@1,COG1629@2	NA|NA|NA	P	TonB-dependent Receptor Plug Domain
MAG.T21.45_03047	1122176.KB903554_gene3847	4.8e-64	251.1	Sphingobacteriia	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000			iLJ478.TM1718	Bacteria	1IPVS@117747,4NDXB@976,COG0036@1,COG0036@2	NA|NA|NA	G	Belongs to the ribulose-phosphate 3-epimerase family
MAG.T21.45_03048	929562.Emtol_3700	7.9e-37	160.2	Cytophagia	elaA	GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564		ko:K02348					ko00000				Bacteria	47QVM@768503,4NQPR@976,COG2153@1,COG2153@2	NA|NA|NA	S	Acetyltransferase (GNAT) domain
MAG.T21.45_03049	760192.Halhy_0625	5.9e-149	533.9	Sphingobacteriia	aroF		2.5.1.54,5.4.99.5	ko:K03856,ko:K04092,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQIZ@117747,4NDU4@976,COG1605@1,COG1605@2,COG2876@1,COG2876@2	NA|NA|NA	E	Dahp synthetase i kdsa
MAG.T21.45_03050	760192.Halhy_0624	3.2e-94	351.7	Sphingobacteriia	tyrA		1.3.1.12,1.3.1.43	ko:K00210,ko:K00220,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025,M00040	R00732,R01728	RC00125	ko00000,ko00001,ko00002,ko01000				Bacteria	1IPH1@117747,4NEKF@976,COG0287@1,COG0287@2	NA|NA|NA	E	Prephenate dehydrogenase
MAG.T21.45_03051	760192.Halhy_0623	2.9e-141	508.4	Sphingobacteriia	dapL		2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1IPSJ@117747,4NF2E@976,COG0436@1,COG0436@2	NA|NA|NA	E	PFAM Aminotransferase, class I
MAG.T21.45_03052	760192.Halhy_0622	1e-90	340.1	Sphingobacteriia	pheA		4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQJU@117747,4NEEK@976,COG0077@1,COG0077@2	NA|NA|NA	E	Prephenate dehydratase
MAG.T21.45_03053	760192.Halhy_0588	2.7e-46	192.6	Sphingobacteriia													Bacteria	1IZ29@117747,4NITC@976,COG0823@1,COG0823@2	NA|NA|NA	U	Involved in the tonB-independent uptake of proteins
MAG.T21.45_03054	1121481.AUAS01000012_gene293	8.1e-42	177.2	Cytophagia				ko:K09164					ko00000				Bacteria	47PZB@768503,4NNWJ@976,COG3358@1,COG3358@2	NA|NA|NA	S	Protein of unknown function (DUF1684)
MAG.T21.45_03055	760192.Halhy_5730	4.6e-39	166.8	Sphingobacteriia	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220		ko:K04078					ko00000,ko03029,ko03110				Bacteria	1ITF1@117747,4NS7D@976,COG0234@1,COG0234@2	NA|NA|NA	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MAG.T21.45_03056	760192.Halhy_5731	8.4e-248	862.8	Sphingobacteriia	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535		ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152				ko00000,ko00001,ko03019,ko03029,ko03110,ko04147				Bacteria	1INP2@117747,4NDZM@976,COG0459@1,COG0459@2	NA|NA|NA	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MAG.T21.45_03057	760192.Halhy_5804	1.5e-23	116.7	Sphingobacteriia	zupT			ko:K07238,ko:K11021,ko:K16267					ko00000,ko02000,ko02042	2.A.5.4.11,2.A.5.5			Bacteria	1ITHR@117747,4NG1R@976,COG0428@1,COG0428@2	NA|NA|NA	P	PFAM zinc iron permease
MAG.T21.45_03058	760192.Halhy_5805	2.6e-34	152.1	Sphingobacteriia	ybjG		3.6.1.27	ko:K19302	ko00550,map00550		R05627	RC00002	ko00000,ko00001,ko01000,ko01011				Bacteria	1ISC5@117747,4NNVQ@976,COG0671@1,COG0671@2	NA|NA|NA	I	Phosphoesterase PA-phosphatase related
MAG.T21.45_03059	1267211.KI669560_gene1995	1.1e-150	540.0	Sphingobacteriia	glmM		5.4.2.10,5.4.2.2,5.4.2.8	ko:K01840,ko:K03431,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R02060,R08639	RC00408	ko00000,ko00001,ko00002,ko01000				Bacteria	1IP3X@117747,4NG3H@976,COG1109@1,COG1109@2	NA|NA|NA	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I
MAG.T21.45_03060	1122176.KB903538_gene1469	2.2e-191	675.2	Bacteroidetes	csdA		2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122		R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029				Bacteria	4NERR@976,COG0520@1,COG0520@2	NA|NA|NA	E	Selenocysteine lyase
MAG.T21.45_03061	1122179.KB890428_gene2935	2.3e-111	409.1	Sphingobacteriia	iscS		2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122		R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029				Bacteria	1INRF@117747,4NFF6@976,COG1104@1,COG1104@2	NA|NA|NA	E	Cysteine desulfurase
MAG.T21.45_03062	760192.Halhy_5552	1.8e-72	279.6	Sphingobacteriia	serA		1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1IX35@117747,4NEMQ@976,COG0111@1,COG0111@2	NA|NA|NA	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MAG.T21.45_03063	760192.Halhy_5553	4.6e-305	1053.9	Sphingobacteriia			2.7.11.1	ko:K08282					ko00000,ko01000				Bacteria	1IPUE@117747,4NG6P@976,COG0553@1,COG0553@2	NA|NA|NA	L	PFAM Helicase conserved C-terminal domain
MAG.T21.45_03064	929562.Emtol_3076	5.6e-138	497.7	Cytophagia													Bacteria	47MJG@768503,4NFWX@976,COG3000@1,COG3000@2	NA|NA|NA	I	Fatty acid hydroxylase superfamily
MAG.T21.45_03065	760192.Halhy_1026	3.4e-78	298.1	Sphingobacteriia	ung	GO:0003674,GO:0003824,GO:0004844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340				ko00000,ko00001,ko01000,ko03400				Bacteria	1IQ5P@117747,4NE2B@976,COG0692@1,COG0692@2	NA|NA|NA	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MAG.T21.45_03066	760192.Halhy_2039	2.6e-84	322.0	Bacteroidetes			3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100		R01206,R02334	RC00467	ko00000,ko00001,ko01000		GH18		Bacteria	4NHTI@976,COG2931@1,COG2931@2,COG3227@1,COG3227@2,COG3292@1,COG3292@2	NA|NA|NA	T	zinc metalloprotease
MAG.T21.45_03067	760192.Halhy_0260	2.2e-158	565.8	Sphingobacteriia	recQ2		3.6.4.12	ko:K03654	ko03018,map03018				ko00000,ko00001,ko01000,ko03400				Bacteria	1IPAP@117747,4NEFD@976,COG0514@1,COG0514@2	NA|NA|NA	L	ATP-dependent DNA helicase RecQ
MAG.T21.45_03068	1122176.KB903531_gene2829	1.6e-72	280.0	Sphingobacteriia													Bacteria	1IWXG@117747,4NH7K@976,COG0438@1,COG0438@2	NA|NA|NA	M	PFAM Glycosyl transferases group 1
MAG.T21.45_03069	376686.Fjoh_2244	9.6e-49	200.7	Flavobacterium													Bacteria	1I05T@117743,2NT61@237,4NQ7P@976,COG1216@1,COG1216@2	NA|NA|NA	S	glycosyl transferase
MAG.T21.45_03070	760192.Halhy_6491	7.6e-143	513.8	Sphingobacteriia													Bacteria	1ISPB@117747,4NGZR@976,COG1680@1,COG1680@2	NA|NA|NA	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein
MAG.T21.45_03072	925409.KI911562_gene1741	2.7e-222	778.5	Sphingobacteriia	ychM		4.2.1.1	ko:K01673,ko:K03321	ko00910,map00910		R00132,R10092	RC02807	ko00000,ko00001,ko01000,ko02000	2.A.53.3		iNJ661.Rv3273	Bacteria	1INYY@117747,4NE9G@976,COG0288@1,COG0288@2,COG0659@1,COG0659@2	NA|NA|NA	P	COGs COG0659 Sulfate permease and related transporter (MFS superfamily)
MAG.T21.45_03073	1121904.ARBP01000005_gene4607	1.9e-98	365.9	Cytophagia	gnl	GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	47KMQ@768503,4NIMX@976,COG3386@1,COG3386@2	NA|NA|NA	G	PFAM SMP-30 Gluconolaconase
MAG.T21.45_03074	1267211.KI669560_gene412	1.5e-77	296.2	Sphingobacteriia			3.4.15.6	ko:K13282			R09722	RC00064,RC00141	ko00000,ko01000,ko01002				Bacteria	1ISHI@117747,4NMM9@976,COG4242@1,COG4242@2	NA|NA|NA	PQ	Belongs to the peptidase S51 family
MAG.T21.45_03075	761193.Runsl_0494	1.2e-121	443.0	Cytophagia			4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120		R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000				Bacteria	47KP7@768503,4NFQY@976,COG1082@1,COG1082@2	NA|NA|NA	G	Xylose isomerase domain protein TIM barrel
MAG.T21.45_03076	153721.MYP_579	5.1e-170	604.4	Cytophagia	yjgR			ko:K06915					ko00000				Bacteria	47M2I@768503,4NF3P@976,COG0433@1,COG0433@2	NA|NA|NA	S	Bacterial protein of unknown function (DUF853)
MAG.T21.45_03077	760192.Halhy_4706	3e-164	585.1	Sphingobacteriia	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.12,6.3.5.6,6.3.5.7	ko:K01876,ko:K02434	ko00970,ko01100,map00970,map01100	M00359,M00360	R03905,R04212,R05577	RC00010,RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	1INQU@117747,4NF3B@976,COG0064@1,COG0064@2	NA|NA|NA	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MAG.T21.45_03078	720555.BATR1942_01765	2.1e-41	175.6	Bacillus	yfiT												Bacteria	1V2BI@1239,1ZG53@1386,4HF8B@91061,COG2318@1,COG2318@2	NA|NA|NA	S	Belongs to the metal hydrolase YfiT family
MAG.T21.45_03079	760192.Halhy_0388	0.0	1150.6	Sphingobacteriia													Bacteria	1ISRU@117747,4NE4M@976,COG1629@1,COG4771@2	NA|NA|NA	P	Carboxypeptidase regulatory-like domain
MAG.T21.45_03080	509635.N824_00475	4.4e-51	208.4	Sphingobacteriia	fdhD	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0043085,GO:0043546,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050790,GO:0065007,GO:0065009,GO:0097159,GO:0097163,GO:0140104,GO:1901363		ko:K02379,ko:K18360	ko00360,map00360		R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001				Bacteria	1IS41@117747,4NFJB@976,COG1526@1,COG1526@2	NA|NA|NA	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MAG.T21.45_03081	929703.KE386491_gene20	2.3e-130	473.0	Cytophagia				ko:K02014					ko00000,ko02000	1.B.14			Bacteria	47M2B@768503,4NE9I@976,COG4772@1,COG4772@2	NA|NA|NA	P	TonB-dependent receptor
MAG.T21.45_03082	760192.Halhy_4669	7.7e-237	827.0	Sphingobacteriia	ptpA_1		3.4.14.5	ko:K01278	ko04974,map04974				ko00000,ko00001,ko01000,ko01002,ko04090,ko04147				Bacteria	1IPE8@117747,4NF70@976,COG0823@1,COG0823@2,COG1506@1,COG1506@2	NA|NA|NA	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region
MAG.T21.45_03084	1122176.KB903554_gene3871	1.7e-63	248.8	Sphingobacteriia				ko:K03719					ko00000,ko03000,ko03036				Bacteria	1IS24@117747,4NMYA@976,COG1522@1,COG1522@2	NA|NA|NA	K	Transcriptional regulator, asnc family
MAG.T21.45_03085	760192.Halhy_6301	1.7e-204	718.8	Sphingobacteriia	gdhA		1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1IPRA@117747,4NEBH@976,COG0334@1,COG0334@2	NA|NA|NA	E	Belongs to the Glu Leu Phe Val dehydrogenases family
MAG.T21.45_03087	760192.Halhy_6299	1.6e-106	392.9	Sphingobacteriia	ccmC	GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748		ko:K02195	ko02010,map02010	M00259			ko00000,ko00001,ko00002,ko02000	3.A.1.107		iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736	Bacteria	1INSK@117747,4NFUS@976,COG0755@1,COG0755@2	NA|NA|NA	O	PFAM Cytochrome c assembly protein
MAG.T21.45_03088	1122176.KB903554_gene3867	2.5e-57	228.8	Sphingobacteriia	ccmB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.41	ko:K02193,ko:K02194	ko02010,map02010	M00259			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107		iECO111_1330.ECO111_2936,iYL1228.KPN_02080	Bacteria	1IP2M@117747,4NFQV@976,COG2386@1,COG2386@2	NA|NA|NA	O	PFAM Cytochrome c-type biogenesis protein CcmB
MAG.T21.45_03089	760192.Halhy_6297	6.6e-95	354.4	Bacteroidetes			3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036				Bacteria	4NHZA@976,COG0860@1,COG0860@2	NA|NA|NA	M	N-acetylmuramoyl-L-alanine amidase
MAG.T21.45_03090	1122176.KB903531_gene2888	5.6e-47	196.8	Bacteria			3.6.1.55	ko:K03574,ko:K06919					ko00000,ko01000,ko03400				Bacteria	COG0467@1,COG0467@2,COG1112@1,COG1112@2	NA|NA|NA	T	regulation of circadian rhythm
MAG.T21.45_03091	760192.Halhy_6295	3.7e-57	228.4	Sphingobacteriia													Bacteria	1IZIE@117747,4PP26@976,COG2207@1,COG2207@2	NA|NA|NA	K	PAS fold
MAG.T21.45_03092	1239962.C943_04607	9.2e-38	162.5	Cytophagia				ko:K07334					ko00000,ko02048				Bacteria	47RJA@768503,4NSZ2@976,COG3549@1,COG3549@2	NA|NA|NA	S	PFAM Plasmid maintenance system killer
MAG.T21.45_03093	1239962.C943_04606	9.5e-42	176.0	Cytophagia	higA			ko:K21498					ko00000,ko02048				Bacteria	47R1U@768503,4NSBZ@976,COG3093@1,COG3093@2	NA|NA|NA	K	TIGRFAM addiction module antidote protein, HigA family
MAG.T21.45_03096	760192.Halhy_0418	6.2e-136	490.7	Sphingobacteriia	atoB		2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147			iJN746.PP_2215	Bacteria	1IP5F@117747,4NE3Q@976,COG0183@1,COG0183@2	NA|NA|NA	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
MAG.T21.45_03097	929562.Emtol_3305	1.1e-254	885.9	Cytophagia			3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603		R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000				Bacteria	47N3F@768503,4PKHN@976,COG1501@1,COG1501@2	NA|NA|NA	G	He_PIG associated, NEW1 domain of bacterial glycohydrolase
MAG.T21.45_03098	925409.KI911562_gene2345	7.2e-54	216.9	Sphingobacteriia	aspG		3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110		R00485	RC00010,RC02798	ko00000,ko00001,ko01000				Bacteria	1IXAX@117747,4NRB3@976,COG0252@1,COG0252@2	NA|NA|NA	EJ	Asparaginase, N-terminal
MAG.T21.45_03099	760192.Halhy_4728	8.5e-17	94.0	Sphingobacteriia	sua5		2.7.7.87,3.5.2.3	ko:K01465,ko:K07566	ko00240,ko01100,map00240,map01100	M00051	R01993,R10463	RC00632,RC00745	ko00000,ko00001,ko00002,ko01000,ko03009,ko03016				Bacteria	1IRXH@117747,4NM43@976,COG0009@1,COG0009@2	NA|NA|NA	J	Belongs to the SUA5 family
MAG.T21.45_03100	1122176.KB903531_gene3077	1.4e-123	450.7	Sphingobacteriia													Bacteria	1IXKI@117747,4NICC@976,COG3291@1,COG3291@2	NA|NA|NA	S	PKD domain containing protein
MAG.T21.45_03101	760192.Halhy_4730	4e-256	891.0	Sphingobacteriia			3.2.1.4,5.2.1.8	ko:K01179,ko:K03768,ko:K08738	ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko03110	3.D.4.6	GH5,GH9		Bacteria	1IXKI@117747,4NICC@976,COG3291@1,COG3291@2	NA|NA|NA	S	PKD domain containing protein
MAG.T21.45_03102	760192.Halhy_4731	7e-43	179.9	Sphingobacteriia	rplS	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02884	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1ISQ9@117747,4NNPW@976,COG0335@1,COG0335@2	NA|NA|NA	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MAG.T21.45_03104	760192.Halhy_0419	0.0	1275.0	Sphingobacteriia	gcvP	GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016638,GO:0016642,GO:0030312,GO:0040007,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.4.4.2	ko:K00281,ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000			iECIAI39_1322.ECIAI39_3318	Bacteria	1INQX@117747,4NEDE@976,COG0403@1,COG0403@2,COG1003@1,COG1003@2	NA|NA|NA	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MAG.T21.45_03105	290315.Clim_1284	1.4e-38	166.8	Chlorobi													Bacteria	1FF7S@1090,COG4704@1,COG4704@2	NA|NA|NA	S	Fibrobacter succinogenes major domain (Fib_succ_major)
MAG.T21.45_03106	313606.M23134_00039	2.2e-199	702.2	Cytophagia													Bacteria	47XJG@768503,4NRE3@976,COG1479@1,COG1479@2,COG3472@1,COG3472@2	NA|NA|NA	S	Protein of unknown function DUF262
MAG.T21.45_03107	1433126.BN938_2528	8.9e-296	1022.7	Rikenellaceae													Bacteria	22UVP@171550,2FMAJ@200643,4NE28@976,COG1061@1,COG1061@2	NA|NA|NA	L	Eco57I restriction-modification methylase
MAG.T21.45_03108	391598.FBBAL38_11469	5.9e-36	157.9	Flavobacteriia													Bacteria	1I4NQ@117743,4NTMP@976,COG4704@1,COG4704@2,COG5295@1,COG5295@2	NA|NA|NA	UW	Hep Hag repeat protein
MAG.T21.45_03109	1305737.JAFX01000001_gene2308	2.9e-214	751.5	Cytophagia			3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100		R06200,R11307,R11308		ko00000,ko00001,ko01000		GH5,GH9		Bacteria	47JTA@768503,4NFJP@976,COG0726@1,COG0726@2	NA|NA|NA	G	Glycosyl hydrolase family 9
MAG.T21.45_03110	865937.Gilli_1362	4.9e-45	188.0	Flavobacteriia													Bacteria	1IBIK@117743,29T8J@1,30EFE@2,4PAB0@976	NA|NA|NA		
MAG.T21.45_03111	865937.Gilli_1363	7.4e-46	190.3	Flavobacteriia	rpoE5			ko:K03088					ko00000,ko03021				Bacteria	1I3SE@117743,4NETF@976,COG1595@1,COG1595@2	NA|NA|NA	K	DNA-directed RNA polymerase specialized sigma subunit sigma24
MAG.T21.45_03112	468059.AUHA01000002_gene1279	1.2e-78	299.7	Sphingobacteriia													Bacteria	1IXZD@117747,4NQCJ@976,COG0346@1,COG0346@2	NA|NA|NA	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase
MAG.T21.45_03113	595460.RRSWK_02626	1.5e-131	476.5	Bacteria													Bacteria	COG3119@1,COG3119@2	NA|NA|NA	P	arylsulfatase activity
MAG.T21.45_03114	1123276.KB893271_gene3976	6.9e-98	364.0	Cytophagia													Bacteria	47TDQ@768503,4NHIY@976,COG3828@1,COG3828@2	NA|NA|NA	S	Trehalose utilisation
MAG.T21.45_03116	866536.Belba_2722	4.5e-26	123.6	Cytophagia				ko:K07487					ko00000				Bacteria	47NCX@768503,4NEDD@976,COG3666@1,COG3666@2	NA|NA|NA	L	PFAM Transposase DDE domain
MAG.T21.45_03117	709991.Odosp_0174	8.5e-63	246.9	Porphyromonadaceae				ko:K07487					ko00000				Bacteria	22WUY@171551,2FNIQ@200643,4NEDD@976,COG3666@1,COG3666@2	NA|NA|NA	L	COG3666 Transposase and inactivated derivatives
MAG.T21.45_03118	1288963.ADIS_3711	2.3e-16	93.2	Cytophagia													Bacteria	2DS33@1,33EB2@2,47WAT@768503,4NYSE@976	NA|NA|NA		
MAG.T21.45_03119	929556.Solca_2420	2.7e-138	498.4	Sphingobacteriia	fpaP		3.4.11.5	ko:K01259	ko00330,map00330		R00135		ko00000,ko00001,ko01000,ko01002				Bacteria	1IQBD@117747,4NFIJ@976,COG2267@1,COG2267@2	NA|NA|NA	I	Serine aminopeptidase, S33
MAG.T21.45_03121	866536.Belba_2615	7.3e-220	770.4	Cytophagia			3.4.17.21	ko:K01301					ko00000,ko01000,ko01002				Bacteria	47MK3@768503,4NI5W@976,COG2234@1,COG2234@2	NA|NA|NA	S	glutamate carboxypeptidase
MAG.T21.45_03122	760192.Halhy_6488	3.8e-289	1000.7	Sphingobacteriia	pdhB		1.2.4.4,2.2.1.1	ko:K00615,ko:K11381	ko00030,ko00280,ko00640,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00280,map00640,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00036,M00165,M00167	R01067,R01641,R01830,R06590,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00032,RC00226,RC00571,RC00627,RC01560,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1IQ4X@117747,4NE4A@976,COG0022@1,COG0022@2,COG1071@1,COG1071@2	NA|NA|NA	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type
MAG.T21.45_03123	760192.Halhy_6487	4.3e-37	161.0	Bacteroidetes				ko:K20276	ko02024,map02024				ko00000,ko00001				Bacteria	4NS8S@976,COG2885@1,COG2885@2	NA|NA|NA	M	Protein of unknown function (DUF1573)
MAG.T21.45_03124	1443665.JACA01000050_gene2098	1.3e-64	253.8	Aquimarina	ampC		3.5.2.6	ko:K01467	ko01501,ko02020,map01501,map02020	M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000				Bacteria	1HWMZ@117743,2YI59@290174,4NFUI@976,COG1680@1,COG1680@2	NA|NA|NA	V	Beta-lactamase
MAG.T21.45_03125	760192.Halhy_4265	1.9e-75	288.9	Sphingobacteriia	recR	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576		ko:K06187	ko03440,map03440				ko00000,ko00001,ko03400				Bacteria	1INZ4@117747,4NEWI@976,COG0353@1,COG0353@2	NA|NA|NA	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MAG.T21.45_03126	1122176.KB903538_gene1506	8e-168	597.4	Sphingobacteriia	wbbL			ko:K07011					ko00000				Bacteria	1IV9F@117747,4NFW5@976,COG1216@1,COG1216@2	NA|NA|NA	M	Glycosyltransferase like family 2
MAG.T21.45_03127	760192.Halhy_5379	6e-15	86.7	Sphingobacteriia	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680		ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2			Bacteria	1IZQE@117747,4PJ7H@976,COG1314@1,COG1314@2	NA|NA|NA	U	Preprotein translocase SecG subunit
MAG.T21.45_03128	1122179.KB890449_gene121	6.8e-07	61.2	Bacteria													Bacteria	2EKU3@1,33EHU@2	NA|NA|NA		
MAG.T21.45_03129	1168034.FH5T_08380	1.1e-43	183.3	Bacteroidia	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66,5.1.1.3	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100		R00260,R00426,R00720,R01855,R02100,R02720,R03531	RC00002,RC00302	ko00000,ko00001,ko01000,ko01011				Bacteria	2FP46@200643,4NM42@976,COG0127@1,COG0127@2	NA|NA|NA	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MAG.T21.45_03131	340177.Cag_0912	1.2e-74	285.8	Bacteria													Bacteria	COG1848@1,COG1848@2	NA|NA|NA	G	Toxic component of a toxin-antitoxin (TA) module. An RNase
MAG.T21.45_03132	714943.Mucpa_2373	3.5e-12	77.0	Sphingobacteriia			3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1IU9E@117747,4NHJM@976,COG2865@1,COG2865@2	NA|NA|NA	K	COGs COG2865 transcriptional regulator protein
MAG.T21.45_03135	290315.Clim_1284	1.1e-16	93.2	Chlorobi													Bacteria	1FF7S@1090,COG4704@1,COG4704@2	NA|NA|NA	S	Fibrobacter succinogenes major domain (Fib_succ_major)
MAG.T21.45_03136	649761.HMPREF0973_02343	3.8e-22	112.1	Bacteroidia													Bacteria	2CEAV@1,2FW0A@200643,32RZH@2,4P333@976	NA|NA|NA		
MAG.T21.45_03138	649761.HMPREF0973_02341	2.9e-07	62.4	Bacteroidia													Bacteria	2C4US@1,2FWYI@200643,33SJ9@2,4P0BH@976	NA|NA|NA	S	Psort location Cytoplasmic, score 8.96
MAG.T21.45_03139	211165.AJLN01000094_gene1131	4.2e-34	151.8	Cyanobacteria													Bacteria	1G60Z@1117,29Z27@1,30KZN@2	NA|NA|NA		
MAG.T21.45_03141	760192.Halhy_3337	2.7e-285	987.6	Sphingobacteriia	rpsA	GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011				Bacteria	1INSH@117747,4NDW9@976,COG0539@1,COG0539@2	NA|NA|NA	J	Ribosomal protein S1
MAG.T21.45_03142	313603.FB2170_08759	2.8e-26	125.6	Flavobacteriia													Bacteria	1I2Z5@117743,4NQKY@976,COG2353@1,COG2353@2	NA|NA|NA	S	Belongs to the UPF0312 family
MAG.T21.45_03143	1121904.ARBP01000018_gene2627	1.5e-103	382.9	Cytophagia													Bacteria	47MAP@768503,4NEUZ@976,COG1262@1,COG1262@2	NA|NA|NA	C	PFAM Formylglycine-generating sulfatase enzyme
MAG.T21.45_03144	1121904.ARBP01000018_gene2626	1.8e-155	555.8	Cytophagia													Bacteria	47JCP@768503,4NF9M@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_03145	929562.Emtol_3101	1.5e-42	180.3	Cytophagia	apbE		2.7.1.180	ko:K03734					ko00000,ko01000				Bacteria	47XH6@768503,4NGEK@976,COG1477@1,COG1477@2	NA|NA|NA	H	ApbE family
MAG.T21.45_03146	760192.Halhy_4300	2.9e-155	556.2	Sphingobacteriia			3.4.21.50	ko:K01337,ko:K07004					ko00000,ko01000,ko01002				Bacteria	1IY1U@117747,4NG2K@976,COG3591@1,COG3591@2	NA|NA|NA	E	Belongs to the peptidase S1B family
MAG.T21.45_03147	760192.Halhy_2643	3.2e-254	884.8	Sphingobacteriia				ko:K14054					ko00000				Bacteria	1IQWN@117747,4NEJA@976,COG2866@1,COG2866@2	NA|NA|NA	E	PFAM Zinc carboxypeptidase
MAG.T21.45_03148	760192.Halhy_2644	1.8e-146	525.4	Sphingobacteriia	metF		1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQZ5@117747,4NDY0@976,COG0685@1,COG0685@2	NA|NA|NA	E	Methylenetetrahydrofolate reductase
MAG.T21.45_03149	1122176.KB903543_gene666	4.4e-73	281.6	Sphingobacteriia	fjo11												Bacteria	1ITHJ@117747,4NEHX@976,COG0697@1,COG0697@2	NA|NA|NA	EG	EamA-like transporter family
MAG.T21.45_03150	760192.Halhy_2807	4.5e-64	250.8	Sphingobacteriia	fur	GO:0000976,GO:0001067,GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141		ko:K03711					ko00000,ko03000				Bacteria	1IRT0@117747,4NM8S@976,COG0735@1,COG0735@2	NA|NA|NA	P	Belongs to the Fur family
MAG.T21.45_03151	1122176.KB903565_gene3282	3.7e-283	980.7	Sphingobacteriia	relA		2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230		R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009				Bacteria	1IQ2F@117747,4NESY@976,COG0317@1,COG0317@2	NA|NA|NA	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MAG.T21.45_03153	1122176.KB903565_gene3397	1.8e-68	266.9	Sphingobacteriia	tig	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564		ko:K03545					ko00000				Bacteria	1ISDW@117747,4NE99@976,COG0544@1,COG0544@2	NA|NA|NA	O	COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)
MAG.T21.45_03154	1122176.KB903565_gene3398	6.3e-99	367.1	Sphingobacteriia	clpP		3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212				ko00000,ko00001,ko01000,ko01002				Bacteria	1IPWN@117747,4NE20@976,COG0740@1,COG0740@2	NA|NA|NA	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MAG.T21.45_03155	1122176.KB903565_gene3399	2.8e-174	618.2	Sphingobacteriia	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575		ko:K03544	ko04112,map04112				ko00000,ko00001,ko03110				Bacteria	1IP06@117747,4NE1B@976,COG1219@1,COG1219@2	NA|NA|NA	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MAG.T21.45_03156	760192.Halhy_3462	7.7e-71	273.9	Sphingobacteriia	truA	GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363	5.4.99.12	ko:K06173					ko00000,ko01000,ko03016				Bacteria	1IPUQ@117747,4NFDC@976,COG0101@1,COG0101@2	NA|NA|NA	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MAG.T21.45_03158	760192.Halhy_2632	3e-49	203.0	Sphingobacteriia													Bacteria	1IRXG@117747,2A79D@1,30W5Z@2,4NN88@976	NA|NA|NA	S	Domain of unknown function (DUF4270)
MAG.T21.45_03159	1122176.KB903560_gene3549	3.2e-91	341.7	Sphingobacteriia	glgA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003		GT5		Bacteria	1IPR7@117747,4NFP8@976,COG0297@1,COG0297@2	NA|NA|NA	G	PFAM Starch synthase, catalytic domain
MAG.T21.45_03160	533240.CRC_02129	5.5e-49	200.7	Cyanobacteria													Bacteria	1GC3Q@1117,COG1672@1,COG1672@2	NA|NA|NA	S	PD-(D/E)XK nuclease superfamily
MAG.T21.45_03161	1217652.F954_00187	1.2e-36	158.7	Moraxellaceae				ko:K07726					ko00000,ko03000				Bacteria	1MZGM@1224,1S97H@1236,3NNZT@468,COG2944@1,COG2944@2	NA|NA|NA	K	Helix-turn-helix
MAG.T21.45_03162	1263831.F543_22760	9.8e-272	942.2	Pasteurellales	yheS_2			ko:K18231	ko02010,map02010				br01600,ko00000,ko00001,ko01504,ko02000	3.A.1.121.1,3.A.1.121.3			Bacteria	1MU37@1224,1RPCU@1236,1Y7FS@135625,COG0488@1,COG0488@2	NA|NA|NA	S	ABC transporter, ATP-binding protein
MAG.T21.45_03163	1263831.F543_22750	8.2e-165	586.3	Gammaproteobacteria	ycbJ			ko:K06979		M00760			br01600,ko00000,ko00002,ko01504				Bacteria	1RBVX@1224,1S39J@1236,COG3173@1,COG3173@2	NA|NA|NA	S	Phosphotransferase enzyme family
MAG.T21.45_03164	40215.BBOS01000099_gene217	1.3e-100	372.5	Moraxellaceae													Bacteria	1MVK6@1224,1S3GZ@1236,3NSN4@468,COG1961@1,COG1961@2	NA|NA|NA	L	Resolvase, N terminal domain
MAG.T21.45_03165	760192.Halhy_3752	2.2e-143	515.8	Sphingobacteriia													Bacteria	1IW1W@117747,4NGJU@976,COG3119@1,COG3119@2	NA|NA|NA	P	Sulfatase
MAG.T21.45_03166	1296415.JACC01000025_gene1632	1.4e-167	596.7	Flavobacteriia			1.11.1.7,1.6.3.1	ko:K13411,ko:K19511	ko04013,ko04624,map04013,map04624				ko00000,ko00001,ko01000,ko04131	5.B.1.2			Bacteria	1I8K4@117743,4NIKN@976,COG2931@1,COG2931@2	NA|NA|NA	Q	Animal haem peroxidase
MAG.T21.45_03167	649349.Lbys_1034	3.2e-47	194.5	Cytophagia				ko:K07032					ko00000				Bacteria	47XTH@768503,4NRTG@976,COG3607@1,COG3607@2	NA|NA|NA	S	Glyoxalase-like domain
MAG.T21.45_03168	761193.Runsl_5478	3.1e-224	785.0	Cytophagia				ko:K02014					ko00000,ko02000	1.B.14			Bacteria	47Y24@768503,4PKCR@976,COG4206@1,COG4206@2	NA|NA|NA	H	TonB dependent receptor
MAG.T21.45_03169	760192.Halhy_4627	0.0	1348.6	Sphingobacteriia													Bacteria	1INSF@117747,4P1Z5@976,COG1629@1,COG4771@2	NA|NA|NA	P	TonB-linked outer membrane protein, SusC RagA family
MAG.T21.45_03170	761193.Runsl_2475	9e-229	799.7	Cytophagia				ko:K21572					ko00000,ko02000	8.A.46.1,8.A.46.3			Bacteria	2DBBU@1,2Z8AF@2,47JIC@768503,4NFUM@976	NA|NA|NA	S	SusD family
MAG.T21.45_03171	760192.Halhy_2204	0.0	1419.4	Sphingobacteriia													Bacteria	1INUZ@117747,4NH6W@976,COG2010@1,COG2010@2,COG2133@1,COG2133@2	NA|NA|NA	C	Cytochrome c
MAG.T21.45_03172	1122176.KB903542_gene389	6.6e-42	177.2	Bacteroidetes	cyaB		4.6.1.1	ko:K01768,ko:K05873	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000				Bacteria	4NQQK@976,COG1437@1,COG1437@2	NA|NA|NA	F	CYTH domain
MAG.T21.45_03173	760192.Halhy_3014	2.2e-79	302.8	Bacteria													Bacteria	COG3173@1,COG3173@2	NA|NA|NA	S	very-long-chain-acyl-CoA dehydrogenase activity
MAG.T21.45_03174	1122176.KB903560_gene3555	1e-224	786.6	Sphingobacteriia													Bacteria	1IPMK@117747,4NFQ6@976,COG2091@1,COG2091@2	NA|NA|NA	H	lysine biosynthetic process via aminoadipic acid
MAG.T21.45_03175	760192.Halhy_1977	1.1e-255	889.0	Sphingobacteriia													Bacteria	1IY44@117747,4NGBK@976,COG2382@1,COG2382@2	NA|NA|NA	P	Putative esterase
MAG.T21.45_03176	760192.Halhy_1976	6.7e-131	473.8	Sphingobacteriia	moaA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0030312,GO:0040007,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0071944,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.22,4.6.1.17	ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122		R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000				Bacteria	1IPUJ@117747,4NFS9@976,COG2896@1,COG2896@2	NA|NA|NA	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MAG.T21.45_03177	760192.Halhy_1975	3.9e-243	847.8	Sphingobacteriia	fdhF												Bacteria	1IRDJ@117747,4NF6W@976,COG0243@1,COG0243@2	NA|NA|NA	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MAG.T21.45_03178	760192.Halhy_6364	7.3e-100	370.9	Sphingobacteriia	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100		R09735	RC03462	ko00000,ko00001,ko01000				Bacteria	1IQAR@117747,4NDYD@976,COG0303@1,COG0303@2	NA|NA|NA	H	MoeA N-terminal region (domain I and II)
MAG.T21.45_03179	929703.KE386491_gene267	3.3e-43	181.4	Cytophagia	moaC	GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122		R11372	RC03425	ko00000,ko00001,ko01000				Bacteria	47PU9@768503,4NHA0@976,COG0315@1,COG0315@2	NA|NA|NA	H	MoaC family
MAG.T21.45_03180	1356852.N008_09175	6.1e-39	167.5	Cytophagia	mobA		2.7.7.77,4.6.1.17	ko:K03637,ko:K03752,ko:K13818	ko00790,ko01100,ko04122,map00790,map01100,map04122		R11372,R11581	RC03425	ko00000,ko00001,ko01000				Bacteria	47NQP@768503,4NMYW@976,COG0746@1,COG0746@2	NA|NA|NA	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MAG.T21.45_03181	760192.Halhy_2220	5.1e-116	424.5	Sphingobacteriia													Bacteria	1IWI9@117747,4NGWY@976,COG0535@1,COG0535@2	NA|NA|NA	C	Radical SAM domain protein
MAG.T21.45_03182	760192.Halhy_2740	1.6e-89	337.0	Sphingobacteriia													Bacteria	1IS3H@117747,4NE6G@976,COG2885@1,COG2885@2	NA|NA|NA	M	Belongs to the ompA family
MAG.T21.45_03183	760192.Halhy_2741	2.1e-81	309.3	Sphingobacteriia													Bacteria	1IPUG@117747,4NEVD@976,COG3064@1,COG3064@2	NA|NA|NA	M	Type IX secretion system membrane protein PorP/SprF
MAG.T21.45_03184	760192.Halhy_2742	1.3e-298	1033.5	Bacteroidetes			3.2.1.4,5.2.1.8	ko:K01179,ko:K03768,ko:K08738	ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko03110	3.D.4.6	GH5,GH9		Bacteria	4P3B4@976,COG2304@1,COG2304@2,COG3291@1,COG3291@2,COG4386@1,COG4386@2,COG4935@1,COG4935@2	NA|NA|NA	O	Immunoglobulin like
MAG.T21.45_03185	760192.Halhy_2751	7.6e-95	354.0	Bacteroidetes			5.5.1.24	ko:K09834	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07502,R07503,R10623,R10624	RC01911	ko00000,ko00001,ko00002,ko01000				Bacteria	2Z7HP@2,4P10P@976,arCOG12964@1	NA|NA|NA	S	Tocopherol cyclase
MAG.T21.45_03186	760192.Halhy_2745	9.2e-73	280.0	Sphingobacteriia	pgdA_1												Bacteria	1IRUN@117747,4NM7D@976,COG0726@1,COG0726@2	NA|NA|NA	G	polysaccharide deacetylase
MAG.T21.45_03187	760192.Halhy_2744	2.5e-177	628.6	Sphingobacteriia	gltX		6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016				Bacteria	1IPV4@117747,4NEED@976,COG0008@1,COG0008@2	NA|NA|NA	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MAG.T21.45_03188	760192.Halhy_3071	1.1e-61	243.4	Bacteroidetes													Bacteria	4NFXM@976,COG1878@1,COG1878@2	NA|NA|NA	S	Metal-dependent hydrolase
MAG.T21.45_03189	760192.Halhy_5784	1.9e-116	426.0	Sphingobacteriia													Bacteria	1IRDC@117747,4NG4D@976,COG2308@1,COG2308@2	NA|NA|NA	S	Evidence 4 Homologs of previously reported genes of
MAG.T21.45_03190	760192.Halhy_2127	6.4e-59	234.2	Sphingobacteriia			5.4.99.23	ko:K06180					ko00000,ko01000,ko03009				Bacteria	1IR96@117747,4NFS8@976,COG0564@1,COG0564@2	NA|NA|NA	J	PFAM Pseudouridine synthase, RsuA and RluB C D E F
MAG.T21.45_03192	760192.Halhy_2125	0.0	1332.8	Sphingobacteriia				ko:K07090					ko00000				Bacteria	1J0WY@117747,4PP1E@976,COG0730@1,COG0730@2	NA|NA|NA	S	Protein of unknown function (DUF2723)
MAG.T21.45_03193	760192.Halhy_3049	1.5e-47	195.7	Sphingobacteriia	rpiB		5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000				Bacteria	1IS85@117747,4NNSU@976,COG0698@1,COG0698@2	NA|NA|NA	G	Ribose 5-phosphate isomerase
MAG.T21.45_03194	1267211.KI669560_gene2098	4.8e-103	381.3	Sphingobacteriia	lys		1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000				Bacteria	1IRKS@117747,4NHDM@976,COG3268@1,COG3268@2	NA|NA|NA	S	Saccharopine dehydrogenase NADP binding domain
MAG.T21.45_03195	1185876.BN8_00103	4.2e-67	261.5	Cytophagia	acdS		1.1.1.401	ko:K21883	ko00051,ko01120,map00051,map01120		R11339	RC00089	ko00000,ko00001,ko01000				Bacteria	47KYX@768503,4NJF6@976,COG4221@1,COG4221@2	NA|NA|NA	S	KR domain
MAG.T21.45_03196	1434325.AZQN01000005_gene3566	1.2e-189	669.5	Cytophagia													Bacteria	47KWC@768503,4NFC9@976,COG3119@1,COG3119@2	NA|NA|NA	P	Domain of unknown function
MAG.T21.45_03197	761193.Runsl_2560	2.8e-128	464.9	Cytophagia													Bacteria	47NTF@768503,4PNCT@976,COG3828@1,COG3828@2	NA|NA|NA	S	Methane oxygenase PmoA
MAG.T21.45_03198	761193.Runsl_2559	1e-170	606.3	Cytophagia													Bacteria	47JXQ@768503,4NIH0@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, C-terminal alpha/beta domain
MAG.T21.45_03199	761193.Runsl_2557	4.4e-234	817.0	Cytophagia													Bacteria	47NH0@768503,4NGHJ@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_03200	760192.Halhy_5872	2e-298	1031.2	Sphingobacteriia				ko:K21572					ko00000,ko02000	8.A.46.1,8.A.46.3			Bacteria	1IP43@117747,4NHQT@976,COG1395@1,COG1395@2	NA|NA|NA	K	RagB SusD domain protein
MAG.T21.45_03201	760192.Halhy_5873	0.0	1662.1	Sphingobacteriia													Bacteria	1IQ56@117747,4NDXS@976,COG1629@1,COG1629@2	NA|NA|NA	P	TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region
MAG.T21.45_03202	760192.Halhy_2364	7.8e-173	613.2	Sphingobacteriia			1.14.17.3	ko:K00504					ko00000,ko01000				Bacteria	1IQ1F@117747,4NH92@976,COG3391@1,COG3391@2	NA|NA|NA	S	NHL repeat containing protein
MAG.T21.45_03203	760192.Halhy_2365	4.1e-241	840.5	Sphingobacteriia													Bacteria	1J0X0@117747,4PKKW@976,COG3119@1,COG3119@2	NA|NA|NA	P	Protein of unknown function (DUF1501)
MAG.T21.45_03204	760192.Halhy_2366	0.0	1401.0	Sphingobacteriia													Bacteria	1IPAR@117747,4NEPV@976,COG2010@1,COG2010@2	NA|NA|NA	C	Protein of unknown function (DUF1553)
MAG.T21.45_03205	1121859.KB890739_gene2802	2.5e-147	529.6	Cytophagia													Bacteria	47NNS@768503,4NEIG@976,COG1629@1,COG4771@2	NA|NA|NA	P	Outer membrane protein beta-barrel family
MAG.T21.45_03206	760192.Halhy_3755	0.0	1112.1	Sphingobacteriia													Bacteria	1IQHX@117747,4NE96@976,COG1434@1,COG1434@2	NA|NA|NA	S	Gram-negative-bacterium-type cell wall biogenesis
MAG.T21.45_03207	1237149.C900_03168	5.8e-21	107.1	Cytophagia													Bacteria	47WJK@768503,4NVXH@976,COG4270@1,COG4270@2	NA|NA|NA	S	Membrane
MAG.T21.45_03208	1123057.P872_19810	3.4e-76	292.4	Cytophagia				ko:K15495	ko02010,map02010	M00423			ko00000,ko00001,ko00002,ko02000	3.A.1.6.5			Bacteria	47NAB@768503,4NHP5@976,COG0725@1,COG0725@2,COG2273@1,COG2273@2	NA|NA|NA	G	Glycosyl hydrolases family 16
MAG.T21.45_03209	1124780.ANNU01000030_gene1122	1.4e-85	322.8	Cytophagia													Bacteria	47JXY@768503,4NHP5@976,COG2273@1,COG2273@2	NA|NA|NA	G	Glycoside hydrolase family 16
MAG.T21.45_03210	1158294.JOMI01000001_gene1924	1.7e-10	73.6	Bacteroidia													Bacteria	2FQYI@200643,4NJAF@976,COG3291@1,COG3291@2	NA|NA|NA	G	Pkd domain containing protein
MAG.T21.45_03211	153721.MYP_2457	1.5e-89	337.0	Cytophagia			1.14.14.47	ko:K00491,ko:K21572	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110		R11711,R11712,R11713	RC00177,RC00330,RC01044	ko00000,ko00001,ko01000,ko02000	8.A.46.1,8.A.46.3			Bacteria	47XXB@768503,4PKHQ@976,COG0702@1,COG0702@2	NA|NA|NA	GM	SusD family
MAG.T21.45_03212	1408813.AYMG01000037_gene38	1.5e-210	740.0	Sphingobacteriia													Bacteria	1IP9H@117747,4NDXS@976,COG1629@1,COG1629@2	NA|NA|NA	P	TonB dependent receptor
MAG.T21.45_03213	391587.KAOT1_06662	1.9e-35	157.9	Bacteria	dexB		2.4.1.7,3.2.1.20,3.2.1.51,3.2.1.70,3.2.1.93,3.2.1.97	ko:K00690,ko:K01187,ko:K01206,ko:K01215,ko:K01226,ko:K17624	ko00052,ko00500,ko00511,ko01100,map00052,map00500,map00511,map01100		R00028,R00801,R00802,R00803,R00837,R06087,R06088,R06113	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000,ko04147		GH101,GH13,GH29,GH31		Bacteria	COG0366@1,COG0366@2	NA|NA|NA	G	hydrolase activity, hydrolyzing O-glycosyl compounds
MAG.T21.45_03214	1120965.AUBV01000003_gene613	1.9e-157	563.5	Cytophagia				ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475			ko00000,ko00001,ko00002,ko02022				Bacteria	47YHS@768503,4PP6K@976,COG2197@1,COG2197@2	NA|NA|NA	KT	Y_Y_Y domain
MAG.T21.45_03215	760192.Halhy_3757	6.6e-146	523.9	Sphingobacteriia													Bacteria	1IP0I@117747,2DB8U@1,2Z7SW@2,4NEUK@976	NA|NA|NA	S	PFAM Alginate lyase
MAG.T21.45_03216	1089547.KB913013_gene1132	1.2e-115	422.5	Cytophagia	hxlA		4.1.2.43,5.3.1.27	ko:K08093,ko:K13831	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05338,R05339,R09780	RC00377,RC00421,RC00422	ko00000,ko00001,ko00002,ko01000				Bacteria	47P5V@768503,4NHBV@976,COG0269@1,COG0269@2	NA|NA|NA	G	Orotidine 5'-phosphate decarboxylase / HUMPS family
MAG.T21.45_03217	240016.ABIZ01000001_gene1929	8.6e-166	589.7	Verrucomicrobiae	gutB		1.1.1.1,1.1.1.14	ko:K00001,ko:K00008	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	M00014	R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko00002,ko01000				Bacteria	2ITRM@203494,46YXT@74201,COG1063@1,COG1063@2	NA|NA|NA	E	Alcohol dehydrogenase GroES-like domain
MAG.T21.45_03218	641524.ADICYQ_0740	1e-102	379.8	Cytophagia													Bacteria	47XQG@768503,4NI0G@976,COG1028@1,COG1028@2	NA|NA|NA	IQ	Enoyl-(Acyl carrier protein) reductase
MAG.T21.45_03219	1123248.KB893381_gene999	3.1e-140	504.6	Bacteroidetes													Bacteria	4NK9X@976,COG1082@1,COG1082@2	NA|NA|NA	G	Xylose isomerase-like TIM barrel
MAG.T21.45_03220	243090.RB9828	2.4e-104	386.0	Planctomycetes													Bacteria	2IWTS@203682,COG1914@1,COG1914@2	NA|NA|NA	P	COG1914 Mn2 and Fe2 transporters of the NRAMP family
MAG.T21.45_03221	1450525.JATV01000013_gene2841	1.6e-67	262.3	Flavobacterium													Bacteria	1I5JZ@117743,2BFRA@1,2P0CA@237,329K3@2,4NR20@976	NA|NA|NA		
MAG.T21.45_03223	1239962.C943_00442	7.6e-162	576.6	Cytophagia													Bacteria	47MJ4@768503,4NHGI@976,COG2141@1,COG2141@2	NA|NA|NA	C	Luciferase-like monooxygenase
MAG.T21.45_03224	983544.Lacal_1809	1.3e-37	162.9	Flavobacteriia													Bacteria	1I4E9@117743,2EA67@1,334B2@2,4NSI0@976	NA|NA|NA		
MAG.T21.45_03225	44060.JODL01000004_gene2662	4.9e-50	204.5	Actinobacteria													Bacteria	2CA5Q@1,2IG9R@201174,2ZV7C@2	NA|NA|NA		
MAG.T21.45_03226	1122975.AQVC01000052_gene1073	9.2e-43	181.4	Bacteria				ko:K07114					ko00000,ko02000	1.A.13.2.2,1.A.13.2.3			Bacteria	COG2304@1,COG2304@2	NA|NA|NA	IU	oxidoreductase activity
MAG.T21.45_03230	397291.C804_04937	6e-25	120.9	Clostridia													Bacteria	1V77T@1239,24JXK@186801,2DM9Z@1,32AR2@2	NA|NA|NA		
MAG.T21.45_03231	1121896.JMLU01000037_gene1906	5.8e-105	387.5	Bacteroidetes	nucS			ko:K07448,ko:K07503					ko00000,ko01000,ko02048				Bacteria	4P1ZR@976,COG1637@1,COG1637@2	NA|NA|NA	L	Pfam:DUF91
MAG.T21.45_03232	886379.AEWI01000057_gene2646	1.7e-289	1002.3	Bacteroidia			2.1.1.72	ko:K07317					ko00000,ko01000,ko02048				Bacteria	2FQ1D@200643,4NEHR@976,COG0827@1,COG0827@2,COG1002@1,COG1002@2	NA|NA|NA	L	COG1002 Type II restriction enzyme methylase subunits
MAG.T21.45_03233	388467.A19Y_3309	0.0	1529.6	Oscillatoriales													Bacteria	1FZVD@1117,1HA6C@1150,COG0553@1,COG0553@2,COG3886@1,COG3886@2	NA|NA|NA	KL	snf2 family
MAG.T21.45_03238	865938.Weevi_0086	6.4e-164	583.6	Flavobacteriia			3.4.16.4	ko:K01286					ko00000,ko01000				Bacteria	1HZWU@117743,4NHA7@976,COG1680@1,COG1680@2	NA|NA|NA	V	Beta-lactamase
MAG.T21.45_03239	1107311.Q767_07370	2.6e-20	104.4	Bacteroidetes													Bacteria	2E0GI@1,32W2H@2,4P3UH@976	NA|NA|NA		
MAG.T21.45_03240	647113.Metok_1381	6.1e-26	124.0	Methanococci			3.1.21.3	ko:K01154					ko00000,ko01000,ko02048				Archaea	23RE6@183939,2XZ3W@28890,COG0732@1,arCOG02628@2157	NA|NA|NA	L	Restriction modification system DNA specificity domain
MAG.T21.45_03241	1120951.AUBG01000013_gene2647	6.9e-17	92.8	Flavobacteriia				ko:K21572					ko00000,ko02000	8.A.46.1,8.A.46.3			Bacteria	1I6P4@117743,4NVCB@976,COG1395@1,COG1395@2	NA|NA|NA	K	Helix-turn-helix XRE-family like proteins
MAG.T21.45_03242	1461577.CCMH01000005_gene1907	3.9e-32	144.1	Flavobacteriia			2.7.11.1	ko:K07154					ko00000,ko01000,ko01001,ko02048				Bacteria	1I43U@117743,4NTCR@976,COG3550@1,COG3550@2	NA|NA|NA	S	HipA N-terminal domain
MAG.T21.45_03243	1150600.ADIARSV_2372	8.3e-118	430.3	Sphingobacteriia			2.7.11.1	ko:K07154					ko00000,ko01000,ko01001,ko02048				Bacteria	1INUF@117747,4NG6N@976,COG3550@1,COG3550@2	NA|NA|NA	S	Pfam:HipA_N
MAG.T21.45_03245	1449350.OCH239_17495	2e-43	183.0	Roseivivax													Bacteria	1RF1J@1224,29IES@1,2UZ7R@28211,305BZ@2,4KNNS@93682	NA|NA|NA		
MAG.T21.45_03246	113355.CM001775_gene3042	5.4e-08	65.1	Cyanobacteria													Bacteria	1G43M@1117,COG2931@1,COG2931@2	NA|NA|NA	Q	calcium- and calmodulin-responsive adenylate cyclase activity
MAG.T21.45_03247	1089547.KB913013_gene3863	1.1e-07	63.9	Cytophagia													Bacteria	29BN2@1,2ZYKD@2,47Q1I@768503,4NQ1N@976	NA|NA|NA		
MAG.T21.45_03249	714943.Mucpa_1732	1.3e-35	156.4	Sphingobacteriia													Bacteria	1IYI6@117747,4NTNZ@976,COG0664@1,COG0664@2	NA|NA|NA	T	Cyclic nucleotide-monophosphate binding domain
MAG.T21.45_03251	1120968.AUBX01000009_gene494	2.1e-121	442.2	Cytophagia				ko:K07341					ko00000,ko02048				Bacteria	47SMD@768503,4NEGN@976,COG3654@1,COG3654@2,COG3943@1,COG3943@2	NA|NA|NA	S	Virulence protein RhuM family
MAG.T21.45_03254	755732.Fluta_1043	2.5e-56	224.9	Flavobacteriia													Bacteria	1IIC8@117743,4NPC8@976,COG0454@1,COG0454@2	NA|NA|NA	K	Psort location Cytoplasmic, score 8.96
MAG.T21.45_03257	153721.MYP_1045	2.5e-121	442.6	Cytophagia	yliI		1.1.5.2	ko:K00117,ko:K21430	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130		R06620	RC00066	ko00000,ko00001,ko01000				Bacteria	47KSC@768503,4NEZC@976,COG2133@1,COG2133@2	NA|NA|NA	G	PFAM Glucose Sorbosone dehydrogenase
MAG.T21.45_03258	760192.Halhy_4098	4e-80	304.7	Bacteria													Bacteria	COG1672@1,COG1672@2	NA|NA|NA		
MAG.T21.45_03259	1461577.CCMH01000003_gene926	1.7e-99	369.4	Flavobacteriia	higA			ko:K18831,ko:K21498					ko00000,ko02048,ko03000				Bacteria	1I1A8@117743,4NHNX@976,COG2856@1,COG2856@2,COG3093@1,COG3093@2	NA|NA|NA	K	Plasmid maintenance system antidote protein
MAG.T21.45_03260	1461577.CCMH01000003_gene927	8.6e-35	152.9	Flavobacteriia													Bacteria	1I6MK@117743,4NT4R@976,COG3549@1,COG3549@2	NA|NA|NA	S	Plasmid maintenance system killer
MAG.T21.45_03261	421531.IX38_07160	9.2e-37	159.5	Chryseobacterium	phnA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464		ko:K06193	ko01120,map01120				ko00000				Bacteria	1I37M@117743,3ZS14@59732,4NEFZ@976,COG2824@1,COG2824@2	NA|NA|NA	P	Phosphonoacetate hydrolase
MAG.T21.45_03262	504487.JCM19302_3544	1.3e-09	71.6	Flavobacteriia													Bacteria	1HZEZ@117743,4P0IA@976,COG0745@1,COG0745@2,COG3292@1,COG3292@2,COG5002@1,COG5002@2	NA|NA|NA	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MAG.T21.45_03263	869213.JCM21142_41883	8.4e-29	134.8	Cytophagia				ko:K21440					ko00000,ko04131				Bacteria	47SYD@768503,4NUMP@976,COG0666@1,COG0666@2,COG4704@1,COG4704@2	NA|NA|NA	S	Fibrobacter succinogenes major domain (Fib_succ_major)
MAG.T21.45_03264	760192.Halhy_2382	1.1e-203	716.1	Sphingobacteriia	asnS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iSDY_1059.SDY_2327	Bacteria	1IPJK@117747,4NDY4@976,COG0017@1,COG0017@2	NA|NA|NA	J	Asparaginyl-tRNA synthetase
MAG.T21.45_03265	471854.Dfer_3461	1.6e-190	673.3	Cytophagia													Bacteria	47M3M@768503,4NGZH@976,COG3250@1,COG3250@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 2 family
MAG.T21.45_03266	760192.Halhy_2934	2.4e-37	161.8	Sphingobacteriia													Bacteria	1J07P@117747,4NNHX@976,COG0526@1,COG0526@2	NA|NA|NA	CO	Thioredoxin
MAG.T21.45_03267	760192.Halhy_2933	2.3e-155	555.8	Bacteroidetes													Bacteria	2CIBF@1,2Z85N@2,4NF0J@976	NA|NA|NA		
MAG.T21.45_03268	760192.Halhy_4007	1.5e-48	199.9	Bacteroidetes													Bacteria	2DMY7@1,32UCK@2,4NSK3@976	NA|NA|NA	S	Outer membrane protein Omp28
MAG.T21.45_03269	909663.KI867150_gene1271	2.3e-26	126.7	Syntrophobacterales			3.4.22.15	ko:K01365,ko:K14475	ko04140,ko04142,ko04145,ko04210,ko04612,ko05143,ko05205,ko05323,ko05418,map04140,map04142,map04145,map04210,map04612,map05143,map05205,map05323,map05418				ko00000,ko00001,ko00537,ko01000,ko01002,ko03110				Bacteria	1RJ0M@1224,2MSFX@213462,2WRZX@28221,42V4Z@68525,COG4870@1,COG4870@2	NA|NA|NA	O	Papain family cysteine protease
MAG.T21.45_03271	760192.Halhy_5781	2e-117	429.1	Sphingobacteriia	dinB	GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904	2.7.7.7	ko:K02346,ko:K03502					ko00000,ko01000,ko03400				Bacteria	1IP49@117747,4NF1Y@976,COG0389@1,COG0389@2	NA|NA|NA	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MAG.T21.45_03272	1250232.JQNJ01000001_gene1564	7.9e-188	663.3	Flavobacteriia	xylA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100		R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000			iECO26_1355.ECO26_5036,iHN637.CLJU_RS08960,iPC815.YPO4038	Bacteria	1HXW8@117743,4NEBQ@976,COG2115@1,COG2115@2	NA|NA|NA	G	Catalyzes the interconversion of D-xylose to D-xylulose
MAG.T21.45_03273	760192.Halhy_3319	7.5e-155	553.9	Sphingobacteriia	xylB	GO:0003674,GO:0003824,GO:0004856,GO:0005975,GO:0005996,GO:0005997,GO:0005998,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:1901575	1.1.1.57,2.7.1.12,2.7.1.17	ko:K00040,ko:K00851,ko:K00854,ko:K19168	ko00030,ko00040,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map01100,map01110,map01120,map01130,map01200	M00014,M00061	R01639,R01737,R02454	RC00002,RC00017,RC00085,RC00538	ko00000,ko00001,ko00002,ko01000,ko02048			iAPECO1_1312.APECO1_2885,iEC55989_1330.EC55989_4019,iECIAI1_1343.ECIAI1_3729,iECO103_1326.ECO103_4670,iECO111_1330.ECO111_4384,iECO26_1355.ECO26_5037,iECOK1_1307.ECOK1_4011,iECP_1309.ECP_3667,iECS88_1305.ECS88_3982,iECSE_1348.ECSE_3838,iECW_1372.ECW_m3838,iEKO11_1354.EKO11_0162,iUMN146_1321.UM146_17990,iUTI89_1310.UTI89_C4105,iWFL_1372.ECW_m3838,iYO844.BSU17610	Bacteria	1IQMH@117747,4NFBZ@976,COG1070@1,COG1070@2	NA|NA|NA	G	PFAM FGGY family of carbohydrate kinases, N-terminal domain
MAG.T21.45_03274	1122176.KB903546_gene997	2.3e-53	215.3	Sphingobacteriia	yorS		3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110		R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000				Bacteria	1ISGT@117747,4NQDT@976,COG4502@1,COG4502@2	NA|NA|NA	S	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MAG.T21.45_03275	760192.Halhy_3496	2.6e-99	368.6	Sphingobacteriia				ko:K06911					ko00000				Bacteria	1ISFC@117747,4NFZD@976,COG1741@1,COG1741@2	NA|NA|NA	S	Pirin C-terminal cupin domain
MAG.T21.45_03276	760192.Halhy_3497	1.3e-26	125.6	Bacteria	catC		5.3.3.4	ko:K03464	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R06990	RC01109	ko00000,ko00001,ko00002,ko01000				Bacteria	COG4829@1,COG4829@2	NA|NA|NA	Q	muconolactone delta-isomerase
MAG.T21.45_03277	1122176.KB903550_gene4292	3.5e-52	213.0	Bacteria													Bacteria	COG3409@1,COG3409@2	NA|NA|NA	M	Peptidoglycan-binding domain 1 protein
MAG.T21.45_03278	760192.Halhy_3948	3.8e-256	891.0	Sphingobacteriia	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430		R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400				Bacteria	1IQAI@117747,4NE2X@976,COG0272@1,COG0272@2	NA|NA|NA	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MAG.T21.45_03279	1313421.JHBV01000027_gene1827	9e-28	131.0	Sphingobacteriia													Bacteria	1IXHW@117747,4PHX4@976,COG3291@1,COG3291@2	NA|NA|NA	N	Pkd domain containing protein
MAG.T21.45_03280	760192.Halhy_2034	6.2e-70	271.6	Sphingobacteriia				ko:K02847	ko00540,ko01100,map00540,map01100	M00080			ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5			Bacteria	1IUM4@117747,4NU0S@976,COG3307@1,COG3307@2	NA|NA|NA	M	O-antigen ligase like membrane protein
MAG.T21.45_03281	760192.Halhy_2035	2.7e-159	568.2	Sphingobacteriia	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1IPG1@117747,4NF8I@976,COG0016@1,COG0016@2	NA|NA|NA	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MAG.T21.45_03282	760192.Halhy_2036	5e-147	527.7	Sphingobacteriia	hisS		6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1IW4I@117747,4NE8N@976,COG0124@1,COG0124@2	NA|NA|NA	J	Histidyl-tRNA synthetase
MAG.T21.45_03283	760192.Halhy_0402	3.2e-76	292.0	Sphingobacteriia			3.5.2.6	ko:K17837	ko01501,map01501		R06363	RC01499	ko00000,ko00001,ko01000				Bacteria	1IV1T@117747,4NHG1@976,COG0491@1,COG0491@2	NA|NA|NA	S	Metallo-beta-lactamase superfamily
MAG.T21.45_03284	626887.J057_21235	3.6e-112	411.8	Alteromonadaceae	mro		5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000				Bacteria	1MVMN@1224,1RNZN@1236,464QA@72275,COG2017@1,COG2017@2	NA|NA|NA	G	Converts alpha-aldose to the beta-anomer
MAG.T21.45_03285	1191523.MROS_0031	4.3e-242	844.0	Bacteria				ko:K03307					ko00000	2.A.21			Bacteria	COG4146@1,COG4146@2	NA|NA|NA	S	symporter activity
MAG.T21.45_03286	392499.Swit_1629	3.7e-27	127.5	Sphingomonadales													Bacteria	1N2W2@1224,2C85M@1,2K6FM@204457,2UD7A@28211,31482@2	NA|NA|NA	S	Stress responsive A/B Barrel Domain
MAG.T21.45_03287	926562.Oweho_2629	8.3e-40	170.6	Flavobacteriia	MA20_22045			ko:K06953					ko00000				Bacteria	1I1BT@117743,4NMCE@976,COG1407@1,COG1407@2	NA|NA|NA	S	metallophosphoesterase
MAG.T21.45_03288	1237149.C900_05690	3.3e-280	971.1	Cytophagia	lhr			ko:K03724					ko00000,ko01000,ko03400				Bacteria	47NAU@768503,4NGQ0@976,COG1201@1,COG1201@2	NA|NA|NA	L	DEAD DEAH box helicase
MAG.T21.45_03289	760192.Halhy_2510	3e-128	465.3	Sphingobacteriia													Bacteria	1IRBZ@117747,4PMAZ@976,COG1913@1,COG1913@2	NA|NA|NA	S	Domain of unknown function (DUF5117)
MAG.T21.45_03290	1168034.FH5T_16190	8.6e-240	836.3	Bacteroidia													Bacteria	2FMAJ@200643,4NE28@976,COG1061@1,COG1061@2	NA|NA|NA	L	restriction endonuclease
MAG.T21.45_03291	1168034.FH5T_16185	9.6e-130	469.9	Bacteroidia			3.1.21.4	ko:K01155					ko00000,ko01000,ko02048				Bacteria	2FQV9@200643,4NIMJ@976,COG1002@1,COG1002@2	NA|NA|NA	L	restriction
MAG.T21.45_03292	1454007.JAUG01000008_gene2097	4.2e-176	624.4	Sphingobacteriia				ko:K07133					ko00000				Bacteria	1IUTK@117747,4NHQG@976,COG1373@1,COG1373@2	NA|NA|NA	S	Domain of unknown function (DUF4143)
MAG.T21.45_03293	1168289.AJKI01000012_gene276	8.4e-142	510.4	Bacteroidia				ko:K07133					ko00000				Bacteria	2FNSN@200643,4NHQG@976,COG1373@1,COG1373@2	NA|NA|NA	S	Psort location Cytoplasmic, score
MAG.T21.45_03294	1123248.KB893333_gene2808	2.2e-109	402.5	Bacteroidetes													Bacteria	4NHD5@976,COG2128@1,COG2128@2	NA|NA|NA	S	Protein of unknown function (DUF3179)
MAG.T21.45_03296	760192.Halhy_3302	3.4e-104	385.2	Sphingobacteriia	paaE			ko:K02613	ko00360,ko01120,map00360,map01120		R09838	RC02690	ko00000,ko00001				Bacteria	1IR7M@117747,4NF24@976,COG1018@1,COG1018@2	NA|NA|NA	C	2Fe-2S iron-sulfur cluster binding domain
MAG.T21.45_03297	1434325.AZQN01000001_gene86	2.5e-22	114.4	Cytophagia													Bacteria	47KG7@768503,4NEND@976,COG2885@1,COG2885@2	NA|NA|NA	M	Belongs to the ompA family
MAG.T21.45_03298	760192.Halhy_2783	6e-276	956.4	Sphingobacteriia	aspS	GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029			iJN678.aspS,iSFV_1184.SFV_1868	Bacteria	1IR7B@117747,4NECY@976,COG0173@1,COG0173@2	NA|NA|NA	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MAG.T21.45_03299	760192.Halhy_2780	1.2e-97	363.6	Sphingobacteriia	hemA	GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040	1.2.1.70	ko:K02407,ko:K02492	ko00860,ko01100,ko01110,ko01120,ko02040,map00860,map01100,map01110,map01120,map02040	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000,ko02035				Bacteria	1IQ3B@117747,4NFTY@976,COG0373@1,COG0373@2	NA|NA|NA	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MAG.T21.45_03300	1127692.HMPREF9075_02364	1.1e-50	206.1	Capnocytophaga	aroQ	GO:0003674,GO:0003824,GO:0003855,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576	3.4.13.9,4.2.1.10	ko:K01271,ko:K03785,ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000,ko01002			iIT341.HP1038,iJN746.PP_0560	Bacteria	1ERZ6@1016,1I20S@117743,4NNHU@976,COG0757@1,COG0757@2	NA|NA|NA	E	Belongs to the type-II 3-dehydroquinase family
MAG.T21.45_03301	1122176.KB903569_gene3481	2.4e-298	1031.2	Sphingobacteriia	recQ		3.6.4.12	ko:K03654	ko03018,map03018				ko00000,ko00001,ko01000,ko03400				Bacteria	1IQ8E@117747,4NEB4@976,COG0514@1,COG0514@2	NA|NA|NA	L	ATP-dependent DNA helicase RecQ
MAG.T21.45_03302	760192.Halhy_3694	6.9e-118	430.6	Sphingobacteriia	manC		2.7.7.13,5.3.1.8,5.4.2.8	ko:K00971,ko:K01840,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01818,R01819	RC00002,RC00376,RC00408	ko00000,ko00001,ko00002,ko01000				Bacteria	1INM4@117747,4NE1Y@976,COG0836@1,COG0836@2	NA|NA|NA	M	mannose-1-phosphate guanylyltransferase
MAG.T21.45_03303	760192.Halhy_3084	2e-96	359.8	Sphingobacteriia	mltD			ko:K08307,ko:K12204					ko00000,ko01000,ko01011,ko02044	3.A.7.10.1,3.A.7.9.1			Bacteria	1IRNH@117747,4NEKW@976,COG0741@1,COG0741@2,COG1388@1,COG1388@2	NA|NA|NA	M	PFAM Transglycosylase SLT domain
MAG.T21.45_03304	760192.Halhy_2932	1.9e-14	84.7	Sphingobacteriia	tatA			ko:K03116	ko03060,ko03070,map03060,map03070	M00336			ko00000,ko00001,ko00002,ko02044	2.A.64			Bacteria	1IUFV@117747,4NUNH@976,COG1826@1,COG1826@2	NA|NA|NA	U	Sec-independent protein translocase protein TatA
MAG.T21.45_03305	1121481.AUAS01000005_gene2067	3.4e-63	248.4	Cytophagia	plsC		2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	47JIM@768503,4NHC8@976,COG0204@1,COG0204@2	NA|NA|NA	I	PFAM Phospholipid glycerol acyltransferase
MAG.T21.45_03306	761193.Runsl_2492	3.7e-142	511.1	Cytophagia	desA1	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0030312,GO:0040007,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071944,GO:0075136	1.14.19.11,1.14.19.2,1.14.19.26	ko:K03921	ko00061,ko01040,ko01212,map00061,map01040,map01212		R03370,R08161,R11108,R11109	RC00917	ko00000,ko00001,ko01000,ko01004				Bacteria	47K8R@768503,4NE91@976,COG0208@1,COG0208@2	NA|NA|NA	F	PFAM Fatty acid desaturase
MAG.T21.45_03307	1121904.ARBP01000003_gene6255	3.5e-201	708.8	Cytophagia													Bacteria	47Y2Y@768503,4PKFW@976,COG4206@1,COG4206@2	NA|NA|NA	H	Outer membrane protein beta-barrel family
MAG.T21.45_03308	1121904.ARBP01000006_gene3739	4.4e-53	215.3	Cytophagia													Bacteria	47M46@768503,4NK1H@976,COG2972@1,COG2972@2	NA|NA|NA	T	Histidine kinase
MAG.T21.45_03309	1121904.ARBP01000006_gene3738	2.4e-58	232.3	Cytophagia													Bacteria	47XE1@768503,4NNIK@976,COG3279@1,COG3279@2	NA|NA|NA	K	PFAM response regulator receiver
MAG.T21.45_03310	760192.Halhy_2749	2.5e-212	745.3	Sphingobacteriia	prc		3.4.21.102	ko:K03797					ko00000,ko01000,ko01002				Bacteria	1IP25@117747,4NFK4@976,COG0793@1,COG0793@2	NA|NA|NA	M	Belongs to the peptidase S41A family
MAG.T21.45_03311	760192.Halhy_2450	2.2e-228	798.5	Sphingobacteriia	yfmR			ko:K15738					ko00000,ko02000	3.A.1.120.6			Bacteria	1IPI4@117747,4NES5@976,COG0488@1,COG0488@2	NA|NA|NA	S	ABC transporter
MAG.T21.45_03312	1454007.JAUG01000012_gene2422	2.7e-118	431.8	Sphingobacteriia			5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100		R01394	RC00511	ko00000,ko00001,ko01000				Bacteria	1IQ15@117747,4NG74@976,COG3622@1,COG3622@2	NA|NA|NA	G	Xylose isomerase
MAG.T21.45_03313	760192.Halhy_3634	6.4e-165	587.4	Sphingobacteriia	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112				ko00000,ko00001,ko01000,ko03032				Bacteria	1IPIQ@117747,4NF8P@976,COG0305@1,COG0305@2,COG1372@1,COG1372@2	NA|NA|NA	L	Participates in initiation and elongation during chromosome replication
MAG.T21.45_03314	760192.Halhy_3502	5.1e-90	337.8	Sphingobacteriia	rluB		5.4.99.19,5.4.99.20,5.4.99.22	ko:K06178,ko:K06181,ko:K06183					ko00000,ko01000,ko03009				Bacteria	1INNI@117747,4NEE1@976,COG1187@1,COG1187@2	NA|NA|NA	J	Belongs to the pseudouridine synthase RsuA family
MAG.T21.45_03315	760192.Halhy_2379	4.1e-27	128.3	Sphingobacteriia													Bacteria	1IZH7@117747,2EN4P@1,32NV8@2,4P9Y2@976	NA|NA|NA		
MAG.T21.45_03316	1122176.KB903548_gene1185	1.4e-67	263.1	Bacteroidetes				ko:K07090					ko00000				Bacteria	4NKPI@976,COG0730@1,COG0730@2	NA|NA|NA	S	membrane transporter protein
MAG.T21.45_03317	984262.SGRA_0556	1.7e-45	188.7	Sphingobacteriia	mce		5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000				Bacteria	1ISVM@117747,4NNGG@976,COG0346@1,COG0346@2	NA|NA|NA	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase
MAG.T21.45_03318	760192.Halhy_2045	1.9e-62	245.7	Sphingobacteriia	yrrM		2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000				Bacteria	1IRTF@117747,4NH42@976,COG4122@1,COG4122@2	NA|NA|NA	S	O-methyltransferase
MAG.T21.45_03319	760192.Halhy_2105	5.4e-60	240.4	Sphingobacteriia													Bacteria	1IYSQ@117747,4P8KP@976,COG3210@1,COG3210@2	NA|NA|NA	U	IMG reference gene
MAG.T21.45_03320	760192.Halhy_1970	4e-61	243.8	Sphingobacteriia													Bacteria	1IUAN@117747,4PM54@976,COG1073@1,COG1073@2	NA|NA|NA	S	alpha beta
MAG.T21.45_03321	1122176.KB903609_gene5264	1.5e-76	292.7	Sphingobacteriia	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464											Bacteria	1IQCX@117747,4NE8Y@976,COG0217@1,COG0217@2	NA|NA|NA	K	transcriptional regulatory protein
MAG.T21.45_03322	760192.Halhy_0134	4.5e-38	164.1	Sphingobacteriia	ccmE			ko:K02197					ko00000				Bacteria	1IT63@117747,4NN85@976,COG2332@1,COG2332@2	NA|NA|NA	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
MAG.T21.45_03323	760192.Halhy_0135	1.6e-302	1045.4	Sphingobacteriia	ccmF			ko:K02198					ko00000,ko02000	9.B.14.1			Bacteria	1IQAC@117747,4NGXI@976,COG1138@1,COG1138@2	NA|NA|NA	O	PFAM Cytochrome c assembly protein
MAG.T21.45_03324	1122176.KB903619_gene5466	6.4e-07	60.1	Sphingobacteriia													Bacteria	1IU6S@117747,2E35A@1,32Y59@2,4NVFH@976	NA|NA|NA		
MAG.T21.45_03325	984262.SGRA_0314	3.3e-78	298.1	Sphingobacteriia	lolD			ko:K09810	ko02010,map02010	M00255			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125			Bacteria	1IPBQ@117747,4NGDU@976,COG1136@1,COG1136@2	NA|NA|NA	V	Part of the ABC transporter complex LolCDE involved in the translocation of
MAG.T21.45_03326	1203554.HMPREF1476_00995	3.3e-24	118.6	Sutterellaceae	pncA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.11.1,3.5.1.19	ko:K08281,ko:K12132	ko00760,ko01100,map00760,map01100		R01268	RC00100	ko00000,ko00001,ko01000,ko01001			iE2348C_1286.E2348C_1895,iECs_1301.ECs2475,iZ_1308.Z2802	Bacteria	1MUGW@1224,2VIMK@28216,4PR2Y@995019,COG1335@1,COG1335@2	NA|NA|NA	Q	Isochorismatase family
MAG.T21.45_03327	880071.Fleli_2954	5.5e-167	594.0	Cytophagia	rocD	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007			iYO844.BSU40340	Bacteria	47K80@768503,4NE93@976,COG4992@1,COG4992@2	NA|NA|NA	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MAG.T21.45_03328	760192.Halhy_5706	2.7e-175	622.9	Sphingobacteriia													Bacteria	1IPPH@117747,4NE4W@976,COG0457@1,COG0457@2,COG1729@1,COG1729@2	NA|NA|NA	S	PFAM Tetratricopeptide
MAG.T21.45_03329	760192.Halhy_5707	1.8e-93	350.1	Sphingobacteriia													Bacteria	1J0XR@117747,4NGYD@976,COG4206@1,COG4206@2	NA|NA|NA	H	Psort location OuterMembrane, score
MAG.T21.45_03330	1538644.KO02_00955	1.2e-103	382.9	Sphingobacteriia													Bacteria	1IQ4Z@117747,4NFDX@976,COG1028@1,COG1028@2	NA|NA|NA	IQ	PFAM Short-chain dehydrogenase reductase SDR
MAG.T21.45_03331	925409.KI911562_gene2481	3.8e-95	354.8	Sphingobacteriia													Bacteria	1IP6Y@117747,4NDUV@976,COG3717@1,COG3717@2	NA|NA|NA	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MAG.T21.45_03332	929562.Emtol_3283	6.3e-236	823.9	Cytophagia													Bacteria	47K3W@768503,4PKVH@976,COG1629@1,COG1629@2	NA|NA|NA	P	PFAM TonB-dependent Receptor Plug
MAG.T21.45_03333	471854.Dfer_0591	9e-44	183.7	Cytophagia				ko:K03088					ko00000,ko03021				Bacteria	47QS7@768503,4NRYN@976,COG1595@1,COG1595@2	NA|NA|NA	K	RNA polymerase sigma factor, sigma-70 family
MAG.T21.45_03334	1434325.AZQN01000003_gene2655	2.4e-48	199.5	Cytophagia				ko:K07165					ko00000				Bacteria	47P7B@768503,4NMDR@976,COG3712@1,COG3712@2	NA|NA|NA	PT	Domain of unknown function (DUF4974)
MAG.T21.45_03335	761193.Runsl_4202	0.0	1582.0	Cytophagia													Bacteria	47YFY@768503,4P258@976,COG4206@1,COG4206@2	NA|NA|NA	H	TonB dependent receptor
MAG.T21.45_03336	761193.Runsl_4203	0.0	1081.2	Cytophagia				ko:K21572					ko00000,ko02000	8.A.46.1,8.A.46.3			Bacteria	47MJH@768503,4NEN3@976,COG0436@1,COG0436@2	NA|NA|NA	E	Pfam:SusD
MAG.T21.45_03337	929562.Emtol_3310	2.2e-227	795.0	Cytophagia													Bacteria	2CD2X@1,2Z7RW@2,47M77@768503,4NI6Q@976	NA|NA|NA		
MAG.T21.45_03338	929562.Emtol_3309	0.0	1360.9	Cytophagia													Bacteria	47N61@768503,4NDYB@976,COG3537@1,COG3537@2	NA|NA|NA	G	Glycosyl hydrolase family 92
MAG.T21.45_03339	1121930.AQXG01000004_gene2889	7.3e-17	94.4	Sphingobacteriia													Bacteria	1IT9D@117747,4NF5P@976,COG2197@1,COG2197@2	NA|NA|NA	T	helix_turn_helix, Lux Regulon
MAG.T21.45_03341	1121930.AQXG01000003_gene2621	1.3e-18	100.1	Bacteroidetes													Bacteria	4NR4G@976,COG2197@1,COG2197@2	NA|NA|NA	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MAG.T21.45_03342	616991.JPOO01000001_gene3174	6.5e-10	72.0	Flavobacteriia													Bacteria	1I2KT@117743,4NQ0S@976,COG2207@1,COG2207@2	NA|NA|NA	K	Helix-turn-helix domain
MAG.T21.45_03343	760192.Halhy_5307	3.9e-138	498.0	Sphingobacteriia	pheS		3.6.4.12,6.1.1.20	ko:K01889,ko:K03655	ko00970,ko03440,map00970,map03440	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03400				Bacteria	1IQ0I@117747,4NFZ1@976,COG1940@1,COG1940@2,COG3398@1,COG3398@2	NA|NA|NA	GK	PFAM ROK family
MAG.T21.45_03344	985255.APHJ01000018_gene3031	1.1e-31	143.3	Flavobacteriia													Bacteria	1I5WC@117743,4NUMP@976,COG4704@1,COG4704@2	NA|NA|NA	S	Fibrobacter succinogenes major domain (Fib_succ_major)
MAG.T21.45_03345	760192.Halhy_0145	2e-184	652.1	Sphingobacteriia	miaB	GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	2.8.4.3	ko:K06168			R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016				Bacteria	1IPSP@117747,4NDU6@976,COG0621@1,COG0621@2	NA|NA|NA	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MAG.T21.45_03346	760192.Halhy_0146	1.3e-142	513.1	Sphingobacteriia	nifA			ko:K03413,ko:K13589	ko02020,ko02030,ko04112,map02020,map02030,map04112	M00506,M00512			ko00000,ko00001,ko00002,ko02022,ko02035				Bacteria	1IPGA@117747,4NDWI@976,COG2204@1,COG2204@2	NA|NA|NA	K	ATPase (AAA
MAG.T21.45_03347	1122176.KB903609_gene5253	2.3e-34	152.1	Sphingobacteriia	lptE												Bacteria	1ISX2@117747,2CADI@1,32RR7@2,4NP51@976	NA|NA|NA	S	Lipopolysaccharide-assembly
MAG.T21.45_03348	1123277.KB893210_gene2879	1.3e-170	606.7	Cytophagia			6.2.1.1,6.2.1.16	ko:K01895,ko:K01907	ko00010,ko00280,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00280,map00620,map00640,map00650,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354,R01357	RC00004,RC00012,RC00014,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	47MVK@768503,4NINZ@976,COG0365@1,COG0365@2	NA|NA|NA	I	AMP-binding enzyme
MAG.T21.45_03350	760192.Halhy_0786	3.6e-27	128.3	Bacteroidetes													Bacteria	2E7UT@1,3329Q@2,4NUQ3@976	NA|NA|NA		
MAG.T21.45_03351	388413.ALPR1_06240	9.1e-145	520.4	Cytophagia				ko:K12941					ko00000,ko01002				Bacteria	47N92@768503,4NEKH@976,COG1473@1,COG1473@2	NA|NA|NA	S	Peptidase dimerisation domain
MAG.T21.45_03352	1122176.KB903554_gene3841	1.8e-80	306.2	Sphingobacteriia	yjfJ	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464		ko:K03969					ko00000				Bacteria	1IZFV@117747,4NIZP@976,COG1842@1,COG1842@2	NA|NA|NA	KT	Phage shock protein A
MAG.T21.45_03353	760192.Halhy_0800	5.1e-152	544.3	Sphingobacteriia	arcA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0008218,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0016990,GO:0018101,GO:0018193,GO:0018195,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130		R00552	RC00177	ko00000,ko00001,ko01000				Bacteria	1IP21@117747,4NHKZ@976,COG2235@1,COG2235@2	NA|NA|NA	E	Arginine deiminase
MAG.T21.45_03354	760192.Halhy_0801	5.8e-49	200.3	Sphingobacteriia	ybgC			ko:K07107					ko00000,ko01000				Bacteria	1IT5E@117747,4NQGW@976,COG0824@1,COG0824@2	NA|NA|NA	S	thioesterase
MAG.T21.45_03355	760192.Halhy_0802	2.2e-86	325.9	Sphingobacteriia	rbn			ko:K03466,ko:K07058					ko00000,ko03036	3.A.12			Bacteria	1IPC8@117747,4NFY6@976,COG1295@1,COG1295@2	NA|NA|NA	S	ribonuclease BN
MAG.T21.45_03356	760192.Halhy_0803	3.4e-96	358.6	Sphingobacteriia													Bacteria	1IR38@117747,4NE43@976,COG2067@1,COG2067@2	NA|NA|NA	I	long-chain fatty acid transport protein
MAG.T21.45_03357	1166018.FAES_0964	1.4e-41	176.4	Cytophagia	lonD		3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112				ko00000,ko00001,ko01000,ko01002				Bacteria	47NJ0@768503,4NEJU@976,COG2802@1,COG2802@2	NA|NA|NA	S	Peptidase S16, lon domain protein
MAG.T21.45_03358	760192.Halhy_0204	0.0	1438.7	Sphingobacteriia				ko:K06894					ko00000				Bacteria	1INMI@117747,4NEW9@976,COG2373@1,COG2373@2	NA|NA|NA	S	alpha-2-macroglobulin domain protein
MAG.T21.45_03359	525373.HMPREF0766_12211	9.2e-97	360.1	Sphingobacteriia													Bacteria	1IQ38@117747,2BZ6M@1,2Z7HW@2,4NDZE@976	NA|NA|NA	S	Domain of Unknown Function (DUF1080)
MAG.T21.45_03360	1122176.KB903609_gene5214	3.8e-68	264.6	Sphingobacteriia	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100		R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000			iSBO_1134.SBO_0893	Bacteria	1IRQM@117747,4NEEC@976,COG0572@1,COG0572@2	NA|NA|NA	F	uridine kinase
MAG.T21.45_03361	760192.Halhy_5138	2.2e-158	565.5	Sphingobacteriia	yeiM			ko:K03317					ko00000	2.A.41			Bacteria	1IRNQ@117747,4NEYN@976,COG1972@1,COG1972@2	NA|NA|NA	F	Na dependent nucleoside transporter
MAG.T21.45_03362	760192.Halhy_0255	2e-42	178.3	Sphingobacteriia	fdx	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840		ko:K04755					ko00000				Bacteria	1ITJK@117747,4NTVJ@976,COG0633@1,COG0633@2	NA|NA|NA	C	2Fe-2S iron-sulfur cluster binding domain
MAG.T21.45_03363	760192.Halhy_0256	7.8e-33	146.0	Sphingobacteriia	iscX	GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772											Bacteria	1ITCB@117747,4NSUG@976,COG2975@1,COG2975@2	NA|NA|NA	S	FeS assembly protein IscX
MAG.T21.45_03364	760192.Halhy_0257	8.6e-50	203.4	Sphingobacteriia	kdsC		3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005				Bacteria	1ISY0@117747,4NMHD@976,COG1778@1,COG1778@2	NA|NA|NA	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase
MAG.T21.45_03365	1046627.BZARG_2476	1e-29	137.5	Flavobacteriia	ubiA		2.5.1.39,2.5.1.42	ko:K03179,ko:K17105	ko00130,ko00564,ko01100,ko01110,map00130,map00564,map01100,map01110	M00117	R04520,R05000,R05615	RC00209,RC01171,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006				Bacteria	1HYXA@117743,4NFRM@976,COG0382@1,COG0382@2	NA|NA|NA	H	UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin
MAG.T21.45_03366	760192.Halhy_0259	3.1e-51	208.4	Sphingobacteriia	maf	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0022402,GO:0022607,GO:0030145,GO:0030312,GO:0030428,GO:0032506,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044085,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047	1.1.1.25,2.1.1.190	ko:K00014,ko:K03215,ko:K06287	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000,ko03009				Bacteria	1ISD6@117747,4NNXV@976,COG0424@1,COG0424@2	NA|NA|NA	D	Maf-like protein
MAG.T21.45_03367	760192.Halhy_5291	3.1e-08	65.1	Sphingobacteriia				ko:K09386					ko00000				Bacteria	1IYK2@117747,4NRMQ@976,COG3427@1,COG3427@2	NA|NA|NA	S	PFAM Carbon monoxide dehydrogenase subunit G (CoxG)
MAG.T21.45_03368	880070.Cycma_1013	2.3e-91	342.4	Bacteroidetes				ko:K03547					ko00000,ko03400				Bacteria	4NG2Q@976,COG0420@1,COG0420@2	NA|NA|NA	L	Calcineurin-like phosphoesterase
MAG.T21.45_03369	388413.ALPR1_15364	6.4e-34	151.0	Cytophagia				ko:K03811					ko00000,ko02000	4.B.1.1			Bacteria	47R6S@768503,4NFJI@976,COG3201@1,COG3201@2	NA|NA|NA	H	TIGRFAM Nicotinamide mononucleotide transporter PnuC
MAG.T21.45_03370	468059.AUHA01000004_gene2200	6.6e-289	1000.0	Sphingobacteriia	quiP		3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130		R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002				Bacteria	1IPU7@117747,4NEIX@976,COG2366@1,COG2366@2	NA|NA|NA	S	COG2366 Protein related to penicillin acylase
MAG.T21.45_03371	468059.AUHA01000004_gene2199	2.8e-20	104.8	Sphingobacteriia													Bacteria	1IU43@117747,2DTGN@1,33K97@2,4NZIF@976	NA|NA|NA		
MAG.T21.45_03372	313596.RB2501_13154	0.0	1354.7	Flavobacteriia													Bacteria	1IJ92@117743,4P258@976,COG4206@1,COG4206@2	NA|NA|NA	H	Outer membrane receptor
MAG.T21.45_03373	1121875.KB907555_gene349	7.8e-236	823.2	Flavobacteriia				ko:K21572					ko00000,ko02000	8.A.46.1,8.A.46.3			Bacteria	1IJC5@117743,4NE3A@976,COG0446@1,COG0446@2	NA|NA|NA	S	SusD family
MAG.T21.45_03374	1121875.KB907555_gene348	0.0	1273.1	Flavobacteriia													Bacteria	1HX4C@117743,4NEE8@976,COG4888@1,COG4888@2	NA|NA|NA	S	PFAM ASPIC and UnbV
MAG.T21.45_03375	760192.Halhy_5256	8.1e-79	301.6	Bacteria													Bacteria	COG1520@1,COG1520@2	NA|NA|NA	S	amino acid activation for nonribosomal peptide biosynthetic process
MAG.T21.45_03376	755732.Fluta_2865	8.6e-59	233.8	Cryomorphaceae	ytpP	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	2.7.1.180,2.7.7.80,2.8.1.11,5.3.4.1	ko:K01829,ko:K03671,ko:K03734,ko:K06196,ko:K21147	ko04122,ko04621,ko05418,map04122,map04621,map05418		R07459,R07461	RC00043	ko00000,ko00001,ko01000,ko02000,ko03110	5.A.1.2			Bacteria	1I51Q@117743,2PC0A@246874,4NUPH@976,COG0526@1,COG0526@2,COG0607@1,COG0607@2	NA|NA|NA	COP	COGs COG0607 Rhodanese-related sulfurtransferase
MAG.T21.45_03377	1278073.MYSTI_04082	2.2e-82	312.4	Proteobacteria	yocS			ko:K03453,ko:K14347					ko00000,ko02000,ko04147	2.A.28,2.A.93.1			Bacteria	1MXF3@1224,COG0385@1,COG0385@2	NA|NA|NA	S	Bile acid sodium symporter
MAG.T21.45_03378	765910.MARPU_08090	1e-20	106.3	Chromatiales				ko:K14673					ko00000,ko01008				Bacteria	1N00P@1224,1S759@1236,1WYP8@135613,COG0662@1,COG0662@2	NA|NA|NA	G	PFAM Cupin
MAG.T21.45_03379	929562.Emtol_4268	3.3e-243	848.2	Cytophagia			3.5.1.81	ko:K06015			R02192	RC00064,RC00328	ko00000,ko01000				Bacteria	47NHH@768503,4NI1Z@976,COG1680@1,COG1680@2,COG3653@1,COG3653@2	NA|NA|NA	QV	Beta-lactamase
MAG.T21.45_03380	1122176.KB903609_gene5258	7.3e-41	173.7	Sphingobacteriia													Bacteria	1ITCQ@117747,4NPQC@976,COG1670@1,COG1670@2	NA|NA|NA	J	Acetyltransferase (GNAT) domain
MAG.T21.45_03381	1123057.P872_18735	1.4e-230	805.4	Cytophagia													Bacteria	47JNX@768503,4NEN5@976,COG0673@1,COG0673@2	NA|NA|NA	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_03382	980584.AFPB01000135_gene3085	4.7e-16	90.5	unclassified Flavobacteriaceae				ko:K19092					ko00000,ko02048				Bacteria	1I3IS@117743,40790@61432,4NQ43@976,COG3668@1,COG3668@2	NA|NA|NA	S	ParE toxin of type II toxin-antitoxin system, parDE
MAG.T21.45_03383	641524.ADICYQ_0655	3.4e-20	104.0	Cytophagia				ko:K07746					ko00000,ko02048				Bacteria	47R4Z@768503,4NSHD@976,COG3609@1,COG3609@2	NA|NA|NA	K	addiction module antidote protein, CC2985 family
MAG.T21.45_03385	435590.BVU_1575	6.6e-33	147.9	Bacteroidaceae													Bacteria	2FNA7@200643,4AP8Z@815,4P14X@976,COG2195@1,COG2195@2	NA|NA|NA	E	Psort location Cytoplasmic, score 8.96
MAG.T21.45_03386	1237149.C900_02754	2.2e-139	502.3	Cytophagia				ko:K06926					ko00000				Bacteria	47NIN@768503,4NE5J@976,COG1106@1,COG1106@2	NA|NA|NA	S	AAA domain, putative AbiEii toxin, Type IV TA system
MAG.T21.45_03387	313595.P700755_003959	1.8e-12	78.2	Flavobacteriia													Bacteria	1I8FE@117743,2DKX2@1,30PJE@2,4NP4Z@976	NA|NA|NA	S	RloB-like protein
MAG.T21.45_03388	760192.Halhy_1950	4.2e-133	481.5	Sphingobacteriia				ko:K07133					ko00000				Bacteria	1IS38@117747,4NHQG@976,COG1373@1,COG1373@2	NA|NA|NA	S	Domain of unknown function (DUF4143)
MAG.T21.45_03389	1122621.ATZA01000025_gene2367	1.4e-68	266.2	Sphingobacteriia				ko:K07133					ko00000				Bacteria	1IQPU@117747,4NE3E@976,COG1373@1,COG1373@2	NA|NA|NA	S	AAA domain
MAG.T21.45_03390	1168289.AJKI01000027_gene1344	6.1e-49	200.3	Marinilabiliaceae				ko:K07133					ko00000				Bacteria	2FP33@200643,3XKNX@558415,4NE3E@976,COG1373@1,COG1373@2	NA|NA|NA	S	AAA domain
MAG.T21.45_03391	1121098.HMPREF1534_01166	4.1e-94	351.3	Bacteroidaceae	tcaR	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141		ko:K21454					ko00000,ko03000				Bacteria	2FNQ5@200643,4AMZ8@815,4NGIN@976,COG1846@1,COG1846@2,COG2184@1,COG2184@2	NA|NA|NA	DK	Fic/DOC family
MAG.T21.45_03392	926551.KB900711_gene1816	5.8e-167	594.0	Bacteroidetes				ko:K06921					ko00000				Bacteria	4NJ2E@976,COG1672@1,COG1672@2	NA|NA|NA	S	ATPase (AAA superfamily)
MAG.T21.45_03393	886379.AEWI01000065_gene2310	2.3e-15	87.8	Bacteroidia													Bacteria	2FTDE@200643,4NQII@976,COG3620@1,COG3620@2	NA|NA|NA	K	DNA-binding helix-turn-helix protein
MAG.T21.45_03394	397291.C804_05108	6.2e-40	171.8	Bacteria													Bacteria	28NVF@1,2ZBTI@2	NA|NA|NA		
MAG.T21.45_03396	655815.ZPR_3981	2.5e-27	128.3	Flavobacteriia				ko:K07484					ko00000				Bacteria	1IK6N@117743,4NEK2@976,COG4974@1,COG4974@2	NA|NA|NA	L	Transposase IS66 family
MAG.T21.45_03397	1123057.P872_20755	9e-58	229.9	Cytophagia	hipA_2		2.7.11.1	ko:K07154					ko00000,ko01000,ko01001,ko02048				Bacteria	47MIR@768503,4NG6N@976,COG3550@1,COG3550@2	NA|NA|NA	S	Pfam:HipA_N
MAG.T21.45_03398	1237149.C900_00688	1.2e-114	419.9	Cytophagia													Bacteria	47TWH@768503,4NSD2@976,COG3177@1,COG3177@2	NA|NA|NA	S	Fic/DOC family
MAG.T21.45_03400	929556.Solca_1967	2.1e-29	134.4	Sphingobacteriia													Bacteria	1IPNN@117747,4NEGN@976,COG3943@1,COG3943@2	NA|NA|NA	S	Virulence protein RhuM family
MAG.T21.45_03401	880071.Fleli_2495	1.9e-37	161.8	Cytophagia				ko:K19166					ko00000,ko01000,ko02048				Bacteria	47RSV@768503,4NTY5@976,COG4680@1,COG4680@2	NA|NA|NA	S	HigB_toxin, RelE-like toxic component of a toxin-antitoxin system
MAG.T21.45_03402	269798.CHU_3507	1e-59	236.5	Cytophagia													Bacteria	47RIS@768503,4NTHF@976,COG3093@1,COG3093@2	NA|NA|NA	K	Helix-turn-helix XRE-family like proteins
MAG.T21.45_03403	1189612.A33Q_1654	7.5e-19	100.1	Cytophagia													Bacteria	28J1N@1,2Z8YI@2,47Q2H@768503,4NH1X@976	NA|NA|NA	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system
MAG.T21.45_03404	313595.P700755_001760	7.9e-47	194.1	Psychroflexus													Bacteria	1HZBX@117743,28KWY@1,2ZAD1@2,4C47G@83612,4NM1H@976	NA|NA|NA		
MAG.T21.45_03405	1118060.CAGZ01000025_gene940	3e-17	94.7	Coriobacteriia													Bacteria	2B28Z@1,2HW4Y@201174,31USS@2,4CY09@84998	NA|NA|NA		
MAG.T21.45_03407	888059.HMPREF9071_0193	1.3e-13	82.0	Capnocytophaga													Bacteria	1EQFF@1016,1HYIM@117743,4NEGN@976,COG3943@1,COG3943@2	NA|NA|NA	S	Toxin-antitoxin system, toxin component, Fic family
MAG.T21.45_03408	1434325.AZQN01000003_gene2569	3.8e-81	308.1	Cytophagia													Bacteria	47TRT@768503,4NJ9G@976,COG5340@1,COG5340@2	NA|NA|NA	K	Transcriptional regulator, AbiEi antitoxin N-terminal domain
MAG.T21.45_03409	616991.JPOO01000001_gene4024	1.5e-83	316.2	Flavobacteriia				ko:K09144					ko00000				Bacteria	1HYWJ@117743,4NFVW@976,COG2253@1,COG2253@2	NA|NA|NA	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system
MAG.T21.45_03410	1433126.BN938_1778	1.5e-60	239.2	Rikenellaceae				ko:K07133					ko00000				Bacteria	22V3S@171550,2G31T@200643,4NED3@976,COG1373@1,COG1373@2	NA|NA|NA	S	AAA domain
MAG.T21.45_03411	1048983.EL17_00710	2.3e-26	124.8	Cytophagia													Bacteria	47VBS@768503,4NQNC@976,COG3657@1,COG3657@2	NA|NA|NA	S	Phage derived protein Gp49-like (DUF891)
MAG.T21.45_03412	504487.JCM19302_3352	2.9e-31	141.0	Flavobacteriia													Bacteria	1I46N@117743,4NSIW@976,COG3636@1,COG3636@2	NA|NA|NA	K	Addiction module
MAG.T21.45_03413	1189612.A33Q_3265	2e-20	104.8	Bacteroidetes				ko:K07729					ko00000,ko03000				Bacteria	4NRXY@976,COG1476@1,COG1476@2	NA|NA|NA	K	Helix-turn-helix
MAG.T21.45_03414	471870.BACINT_00303	1.1e-145	523.1	Bacteroidaceae				ko:K07133					ko00000				Bacteria	2FME1@200643,4ANMQ@815,4NE39@976,COG1373@1,COG1373@2	NA|NA|NA	S	Psort location Cytoplasmic, score 8.96
MAG.T21.45_03415	313595.P700755_002359	6.7e-126	456.8	Flavobacteriia	draG												Bacteria	1I51T@117743,4NNUH@976,COG1397@1,COG1397@2	NA|NA|NA	O	ADP-ribosylglycohydrolase
MAG.T21.45_03417	877411.JMMA01000002_gene603	4.4e-92	345.1	Ruminococcaceae				ko:K07133					ko00000				Bacteria	1TP7X@1239,247ZX@186801,3WGAI@541000,COG1373@1,COG1373@2	NA|NA|NA	S	Psort location Cytoplasmic, score
MAG.T21.45_03419	385682.AFSL01000073_gene1379	4.7e-09	67.4	Bacteroidia													Bacteria	2EJGQ@1,2FZAF@200643,33D7M@2,4NZNE@976	NA|NA|NA		
MAG.T21.45_03420	760192.Halhy_2280	3.3e-263	914.8	Sphingobacteriia													Bacteria	1IYUX@117747,4PIZU@976,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2	NA|NA|NA	C	Cytochrome c
MAG.T21.45_03421	760192.Halhy_2281	1.4e-81	309.7	Sphingobacteriia			5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQY9@117747,4NGKX@976,COG1082@1,COG1082@2	NA|NA|NA	G	Xylose isomerase domain protein TIM barrel
MAG.T21.45_03422	926559.JoomaDRAFT_1106	6.9e-16	89.7	Flavobacteriia													Bacteria	1I586@117743,4NW90@976,COG3093@1,COG3093@2	NA|NA|NA	K	Helix-turn-helix XRE-family like proteins
MAG.T21.45_03423	761193.Runsl_0634	3.1e-18	97.8	Cytophagia													Bacteria	47S62@768503,4NVKN@976,COG1708@1,COG1708@2	NA|NA|NA	L	Nucleotidyltransferase domain
MAG.T21.45_03424	761193.Runsl_0635	4.5e-27	127.5	Cytophagia				ko:K09132					ko00000				Bacteria	47SIT@768503,4NVCM@976,COG1895@1,COG1895@2	NA|NA|NA	S	HEPN domain
MAG.T21.45_03425	1034807.FBFL15_2654	2e-138	499.2	Flavobacteriia				ko:K07133					ko00000				Bacteria	1I2E3@117743,4NHQG@976,COG1373@1,COG1373@2	NA|NA|NA	S	Domain of unknown function (DUF4143)
MAG.T21.45_03426	445683.E3SJZ5_9CAUD	1.2e-53	218.0	Myoviridae													Viruses	4QBUC@10239,4QHY3@10662,4QQGQ@28883	NA|NA|NA		
MAG.T21.45_03427	391587.KAOT1_08398	4.3e-10	70.1	Flavobacteriia													Bacteria	1I6CK@117743,2DZK1@1,32VCS@2,4NTZ5@976	NA|NA|NA		
MAG.T21.45_03428	1267211.KI669560_gene1668	1.1e-49	203.0	Sphingobacteriia			6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1IUQX@117747,4NMB7@976,COG1670@1,COG1670@2	NA|NA|NA	J	Acetyltransferase (GNAT) domain
MAG.T21.45_03429	760192.Halhy_3745	2.7e-180	638.6	Sphingobacteriia	nirS	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000				Bacteria	1IWUH@117747,4NIKG@976,COG2010@1,COG2010@2,COG2133@1,COG2133@2	NA|NA|NA	C	Glucose / Sorbosone dehydrogenase
MAG.T21.45_03430	1131812.JQMS01000001_gene988	3.3e-56	224.2	Flavobacterium													Bacteria	1I6FE@117743,2NWFZ@237,31TV8@2,4NQJ7@976,COG2259@1	NA|NA|NA	S	DoxX-like family
MAG.T21.45_03431	1120965.AUBV01000006_gene2195	3.1e-138	498.0	Cytophagia													Bacteria	47P2Y@768503,4PKKH@976,COG0657@1,COG0657@2	NA|NA|NA	I	alpha/beta hydrolase fold
MAG.T21.45_03432	1336803.PHEL49_2579	1.9e-128	466.5	Polaribacter													Bacteria	1HYYH@117743,3VWJ7@52959,4NF1X@976,COG3119@1,COG3119@2	NA|NA|NA	P	Sulfatase
MAG.T21.45_03433	439292.Bsel_0593	4.2e-29	134.0	Bacteria													Bacteria	2CWZM@1,32T0R@2	NA|NA|NA	S	DoxX-like family
MAG.T21.45_03434	1189620.AJXL01000015_gene955	2.2e-14	84.7	Flavobacterium													Bacteria	1IDVK@117743,2E4HW@1,2NZBD@237,302B1@2,4PJBA@976	NA|NA|NA	S	DoxX-like family
MAG.T21.45_03435	929562.Emtol_3096	1.4e-131	476.5	Cytophagia			1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000				Bacteria	47NSQ@768503,4NKW2@976,COG1231@1,COG1231@2	NA|NA|NA	E	Flavin containing amine oxidoreductase
MAG.T21.45_03436	938709.AUSH02000051_gene242	7.9e-103	380.2	Bacteroidetes													Bacteria	4NEMK@976,COG0300@1,COG0300@2	NA|NA|NA	S	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAG.T21.45_03440	395493.BegalDRAFT_3303	9.3e-08	62.4	Bacteria													Bacteria	2EB3G@1,33547@2	NA|NA|NA		
MAG.T21.45_03441	1121870.AUAA01000054_gene1138	6.7e-126	456.8	Flavobacteriia													Bacteria	1HZKX@117743,4NEWM@976,COG0384@1,COG0384@2	NA|NA|NA	S	phenazine biosynthesis protein, PhzF family
MAG.T21.45_03442	1121481.AUAS01000013_gene4136	2.7e-200	705.3	Cytophagia			3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142		R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042		GH33		Bacteria	47NCK@768503,4PKM0@976,COG1073@1,COG1073@2	NA|NA|NA	S	alpha beta
MAG.T21.45_03444	1288963.ADIS_3502	4.9e-100	370.9	Cytophagia													Bacteria	28PB4@1,2ZC42@2,47P4V@768503,4NJ4V@976	NA|NA|NA		
MAG.T21.45_03445	1227739.Hsw_PA0075	7.1e-41	174.9	Cytophagia													Bacteria	47KG1@768503,4NI2T@976,COG3292@1,COG3292@2	NA|NA|NA	T	PFAM Two component regulator propeller
MAG.T21.45_03446	1107311.Q767_00230	9.7e-40	169.5	Bacteria				ko:K07032					ko00000				Bacteria	COG0346@1,COG0346@2	NA|NA|NA	E	lactoylglutathione lyase activity
MAG.T21.45_03447	866536.Belba_3131	3.1e-149	534.6	Cytophagia	rhuM												Bacteria	47PMW@768503,4NEGN@976,COG3943@1,COG3943@2	NA|NA|NA	S	Virulence protein RhuM family
MAG.T21.45_03448	1270196.JCKI01000010_gene818	1e-100	373.2	Bacteroidetes													Bacteria	4NIG0@976,COG3617@1,COG3617@2	NA|NA|NA	K	BRO family, N-terminal domain
MAG.T21.45_03449	1279009.ADICEAN_02725	9.1e-12	75.9	Cytophagia													Bacteria	47S8E@768503,4NYD2@976,COG2886@1,COG2886@2	NA|NA|NA	S	Uncharacterised protein family (UPF0175)
MAG.T21.45_03450	867902.Ornrh_1353	9.1e-66	257.3	Bacteroidetes													Bacteria	28QUT@1,2ZDA3@2,4NMZZ@976	NA|NA|NA		
MAG.T21.45_03451	866536.Belba_2986	5.4e-84	317.4	Cytophagia				ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	47QRT@768503,4NIVX@976,COG1131@1,COG1131@2	NA|NA|NA	V	ABC-type multidrug transport system ATPase component
MAG.T21.45_03452	760192.Halhy_0549	9.1e-234	816.2	Sphingobacteriia													Bacteria	1IVSV@117747,28JP4@1,2Z9F6@2,4NDYM@976	NA|NA|NA		
MAG.T21.45_03453	1121012.AUKX01000089_gene988	1.5e-105	389.0	Flavobacteriia													Bacteria	1I21H@117743,4NK81@976,COG0300@1,COG0300@2	NA|NA|NA	S	Enoyl-(Acyl carrier protein) reductase
MAG.T21.45_03454	1189612.A33Q_0593	2e-62	245.4	Cytophagia			1.8.4.11,1.8.4.12	ko:K12267					ko00000,ko01000				Bacteria	47X6F@768503,4NRQ5@976,COG2320@1,COG2320@2	NA|NA|NA	S	GrpB protein
MAG.T21.45_03456	760192.Halhy_3222	3e-66	259.2	Sphingobacteriia	Z012_00180		3.1.1.5	ko:K10804	ko01040,map01040				ko00000,ko00001,ko01000,ko01004				Bacteria	1IRWS@117747,4NK39@976,COG2755@1,COG2755@2	NA|NA|NA	E	COG2755 Lysophospholipase L1 and related esterases
MAG.T21.45_03457	1267211.KI669560_gene465	1.4e-141	509.6	Bacteroidetes			1.13.12.3	ko:K00466	ko00380,map00380		R00679	RC00213	ko00000,ko00001,ko01000				Bacteria	4NFI3@976,COG1228@1,COG1228@2	NA|NA|NA	Q	COG1228 Imidazolonepropionase and related
MAG.T21.45_03458	1379858.N508_01014	1.1e-93	350.5	Deferribacteres				ko:K07133					ko00000				Bacteria	2GFTD@200930,COG1373@1,COG1373@2	NA|NA|NA	S	AAA domain
MAG.T21.45_03460	929562.Emtol_2232	0.0	1194.1	Cytophagia			1.3.99.16	ko:K07303					ko00000,ko01000				Bacteria	47KPV@768503,4NFFU@976,COG1529@1,COG1529@2	NA|NA|NA	C	Aldehyde oxidase and xanthine dehydrogenase molybdopterin binding
MAG.T21.45_03461	929562.Emtol_2231	3e-70	271.2	Cytophagia			1.3.99.16	ko:K07302,ko:K07303					ko00000,ko01000				Bacteria	47PA8@768503,4NM72@976,COG2080@1,COG2080@2	NA|NA|NA	C	2Fe-2S -binding domain
MAG.T21.45_03462	866536.Belba_2374	1.9e-20	104.8	Cytophagia													Bacteria	2EA6H@1,334B9@2,47X36@768503,4NUWX@976	NA|NA|NA		
MAG.T21.45_03463	866536.Belba_2375	8.7e-38	162.9	Bacteroidetes				ko:K07171					ko00000,ko01000,ko02048				Bacteria	4NRIX@976,COG2337@1,COG2337@2	NA|NA|NA	L	Toxic component of a toxin-antitoxin (TA) module
MAG.T21.45_03464	929562.Emtol_0692	1.9e-72	279.6	Cytophagia			3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	47RTI@768503,4NNEW@976,COG3386@1,COG3386@2	NA|NA|NA	G	Arylesterase
MAG.T21.45_03465	1122176.KB903532_gene2712	5.2e-124	451.1	Sphingobacteriia			3.1.3.97	ko:K07053			R00188,R11188	RC00078	ko00000,ko01000				Bacteria	1ISEJ@117747,4NHZ5@976,COG0613@1,COG0613@2	NA|NA|NA	S	Domain of unknown function
MAG.T21.45_03466	1408473.JHXO01000004_gene109	7.1e-195	687.6	Bacteroidia			2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501				ko00000,ko00001,ko01000,ko01003,ko01011		GT51		Bacteria	2FNBG@200643,4NECJ@976,COG5009@1,COG5009@2	NA|NA|NA	M	transglycosylase
MAG.T21.45_03467	760192.Halhy_3306	5.4e-223	780.4	Sphingobacteriia	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535		ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152				ko00000,ko00001,ko03019,ko03029,ko03110,ko04147				Bacteria	1INP2@117747,4NDZM@976,COG0459@1,COG0459@2	NA|NA|NA	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MAG.T21.45_03468	1122179.KB890422_gene2196	8e-34	149.4	Sphingobacteriia	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220		ko:K04078					ko00000,ko03029,ko03110				Bacteria	1ITF1@117747,4NS7D@976,COG0234@1,COG0234@2	NA|NA|NA	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MAG.T21.45_03469	1453500.AT05_01875	1.8e-213	749.2	Flavobacteriia	fecA			ko:K16091					ko00000,ko02000	1.B.14.1.14			Bacteria	1HZ6R@117743,4NH5V@976,COG4772@1,COG4772@2	NA|NA|NA	P	Outer membrane receptor for Fe3 -dicitrate
MAG.T21.45_03470	1313421.JHBV01000039_gene2646	1.5e-29	136.3	Sphingobacteriia	ushA		3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45	ko:K01081,ko:K01119,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110		R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135	RC00017,RC00078,RC00296	ko00000,ko00001,ko01000				Bacteria	1ITBW@117747,4NR6D@976,COG0737@1,COG0737@2	NA|NA|NA	F	5'-nucleotidase
MAG.T21.45_03471	1122179.KB890497_gene2773	1.2e-94	353.2	Sphingobacteriia			3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110		R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000				Bacteria	1IQB8@117747,4NESM@976,COG0737@1,COG0737@2	NA|NA|NA	F	Belongs to the 5'-nucleotidase family
MAG.T21.45_03472	269798.CHU_0236	4.5e-56	224.2	Cytophagia				ko:K07491					ko00000				Bacteria	47Q23@768503,4NQTF@976,COG1943@1,COG1943@2	NA|NA|NA	L	transposase IS200-family protein
MAG.T21.45_03473	929703.KE386491_gene4244	4.4e-60	238.0	Cytophagia	radC			ko:K03630					ko00000				Bacteria	47KTY@768503,4NFBF@976,COG2003@1,COG2003@2	NA|NA|NA	E	Belongs to the UPF0758 family
MAG.T21.45_03474	760192.Halhy_2765	1e-21	109.8	Sphingobacteriia	rnpA	GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536,ko:K08998					ko00000,ko01000,ko03016				Bacteria	1IT9C@117747,4NUMM@976,COG0594@1,COG0594@2	NA|NA|NA	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MAG.T21.45_03476	760192.Halhy_0337	8.9e-263	912.9	Sphingobacteriia	tkt	GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030312,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000			iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,iYL1228.KPN_02799,ic_1306.c2990	Bacteria	1INZ8@117747,4P14U@976,COG0021@1,COG0021@2	NA|NA|NA	G	Belongs to the transketolase family
MAG.T21.45_03477	760192.Halhy_0294	1.4e-89	335.9	Sphingobacteriia	tal	GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000				Bacteria	1IP8P@117747,4NFVZ@976,COG0176@1,COG0176@2	NA|NA|NA	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MAG.T21.45_03478	1173027.Mic7113_4223	1.9e-38	165.2	Oscillatoriales													Bacteria	1G71C@1117,1HBXK@1150,COG0614@1,COG0614@2	NA|NA|NA	P	PD-(D/E)XK nuclease superfamily
MAG.T21.45_03479	1122176.KB903543_gene641	1.1e-172	612.8	Sphingobacteriia	bcd		1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212		R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000				Bacteria	1IPN4@117747,4NEHA@976,COG1960@1,COG1960@2	NA|NA|NA	I	acyl-CoA dehydrogenase
MAG.T21.45_03480	866536.Belba_0411	0.0	1128.2	Cytophagia				ko:K02014					ko00000,ko02000	1.B.14			Bacteria	47MJ2@768503,4NFJJ@976,COG1629@1,COG4771@2	NA|NA|NA	P	TonB dependent receptor
MAG.T21.45_03481	760192.Halhy_1949	0.0	1622.8	Sphingobacteriia	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iG2583_1286.G2583_0027,iPC815.YPO0475	Bacteria	1IPPT@117747,4NEYT@976,COG0060@1,COG0060@2	NA|NA|NA	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MAG.T21.45_03482	984262.SGRA_1945	3e-68	265.4	Sphingobacteriia													Bacteria	1INUG@117747,4NF25@976,COG0204@1,COG0204@2	NA|NA|NA	I	Acyltransferase
MAG.T21.45_03483	760192.Halhy_0016	4.2e-145	521.5	Sphingobacteriia	betT												Bacteria	1IS8T@117747,4NEIW@976,COG1292@1,COG1292@2	NA|NA|NA	U	Belongs to the BCCT transporter (TC 2.A.15) family
MAG.T21.45_03484	329726.AM1_2681	9.2e-07	62.0	Cyanobacteria													Bacteria	1G59D@1117,COG5094@1,COG5094@2	NA|NA|NA	K	RNA polymerase II transcriptional preinitiation complex assembly
MAG.T21.45_03485	760192.Halhy_3215	4.9e-160	570.9	Sphingobacteriia	sucB	GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_2766,iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722	Bacteria	1IP4Q@117747,4NF33@976,COG0508@1,COG0508@2	NA|NA|NA	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MAG.T21.45_03486	760192.Halhy_3193	4e-110	404.4	Sphingobacteriia	lgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.1.1.199	ko:K03438,ko:K13292					ko00000,ko01000,ko03009				Bacteria	1IQYZ@117747,4NFP7@976,COG0682@1,COG0682@2	NA|NA|NA	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MAG.T21.45_03487	1122176.KB903542_gene336	1.9e-85	322.8	Bacteroidetes	ftcD		2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100		R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147				Bacteria	4NFE3@976,COG3404@1,COG3404@2,COG3643@1,COG3643@2	NA|NA|NA	E	Glutamate formimidoyltransferase
MAG.T21.45_03488	760192.Halhy_3095	4.2e-154	551.2	Sphingobacteriia	yhdP			ko:K03699,ko:K06189					ko00000,ko02000,ko02042	9.A.40.1.2			Bacteria	1IQ0A@117747,4NDZ7@976,COG1253@1,COG1253@2	NA|NA|NA	S	PFAM CBS domain
MAG.T21.45_03489	926556.Echvi_3865	0.0	1130.2	Cytophagia	MA20_43170			ko:K06911					ko00000				Bacteria	47JNC@768503,4NEK3@976,COG0247@1,COG0247@2,COG0277@1,COG0277@2	NA|NA|NA	C	FAD linked oxidases, C-terminal domain
MAG.T21.45_03491	760192.Halhy_2779	4.7e-45	188.0	Sphingobacteriia													Bacteria	1ISFV@117747,2CI1G@1,2Z7JA@2,4NF1T@976	NA|NA|NA	S	Domain of unknown function (DUF4294)
MAG.T21.45_03492	760192.Halhy_3693	4e-47	195.7	Sphingobacteriia			2.4.1.52	ko:K00712,ko:K13004					ko00000,ko01000,ko01003,ko01005		GT4		Bacteria	1IT3G@117747,4NEX8@976,COG0438@1,COG0438@2	NA|NA|NA	M	COG0438 Glycosyltransferase
MAG.T21.45_03493	760192.Halhy_3691	3.8e-46	192.6	Bacteria													Bacteria	COG0438@1,COG0438@2	NA|NA|NA	M	transferase activity, transferring glycosyl groups
MAG.T21.45_03494	760192.Halhy_1996	2.7e-163	582.0	Sphingobacteriia													Bacteria	1INYG@117747,4PKJY@976,COG0318@1,COG0318@2	NA|NA|NA	IQ	PFAM GH3 auxin-responsive promoter
MAG.T21.45_03495	760192.Halhy_2588	0.0	1357.8	Sphingobacteriia	uvrA			ko:K03701	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	1INYW@117747,4NFQU@976,COG0178@1,COG0178@2	NA|NA|NA	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MAG.T21.45_03496	362418.IW19_03075	1.6e-81	309.3	Flavobacterium	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_0388	Bacteria	1HWQ2@117743,2NSIF@237,4NEEX@976,COG0106@1,COG0106@2	NA|NA|NA	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MAG.T21.45_03497	547042.BACCOPRO_01267	1.2e-66	259.6	Bacteroidaceae	hisH	GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234		ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000			iECED1_1282.ECED1_2372,iPC815.YPO1545,iYL1228.KPN_02479	Bacteria	2FPAY@200643,4AK6D@815,4NF4J@976,COG0118@1,COG0118@2	NA|NA|NA	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MAG.T21.45_03498	760192.Halhy_3420	6.2e-141	507.3	Sphingobacteriia	hisB	GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034200,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,2.6.1.9,3.1.3.15,3.1.3.82,3.1.3.83,4.2.1.19	ko:K00013,ko:K00817,ko:K01089,ko:K01693,ko:K03273	ko00340,ko00350,ko00360,ko00400,ko00401,ko00540,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00540,map00960,map01100,map01110,map01130,map01230	M00026,M00064	R00694,R00734,R01158,R01163,R03012,R03013,R03243,R03457,R05647,R09771	RC00006,RC00017,RC00099,RC00242,RC00463,RC00888,RC00932	ko00000,ko00001,ko00002,ko01000,ko01005,ko01007			iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iLJ478.TM1039,iSB619.SA_RS14130,iUMNK88_1353.UMNK88_2570	Bacteria	1IP4B@117747,4NENP@976,COG0131@1,COG0131@2,COG0241@1,COG0241@2	NA|NA|NA	E	belongs to the imidazoleglycerol-phosphate dehydratase family
MAG.T21.45_03499	509635.N824_17950	3.8e-108	398.3	Sphingobacteriia	hisC		1.1.1.23,2.6.1.9	ko:K00013,ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R01158,R01163,R03012,R03243	RC00006,RC00099,RC00242,RC00463,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1IVB1@117747,4NEDI@976,COG0079@1,COG0079@2	NA|NA|NA	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MAG.T21.45_03500	1379270.AUXF01000005_gene748	1.2e-65	257.3	Gemmatimonadetes													Bacteria	1ZTN0@142182,2DI2U@1,301UZ@2	NA|NA|NA		
MAG.T21.45_03501	760192.Halhy_3418	1.7e-139	502.7	Sphingobacteriia	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,1.1.1.308	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQWR@117747,4NFPZ@976,COG0141@1,COG0141@2	NA|NA|NA	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MAG.T21.45_03502	760192.Halhy_3417	3e-108	398.3	Sphingobacteriia	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000			iECSF_1327.ECSF_1909	Bacteria	1IQIJ@117747,4NDW8@976,COG0040@1,COG0040@2	NA|NA|NA	E	ATP phosphoribosyltransferase
MAG.T21.45_03504	760192.Halhy_2563	8.8e-41	174.1	Bacteria				ko:K09933					ko00000,ko01002				Bacteria	COG3228@1,COG3228@2	NA|NA|NA	S	metallopeptidase activity
MAG.T21.45_03506	398720.MED217_02845	6.4e-39	167.5	Leeuwenhoekiella	cutC	GO:0006873,GO:0006875,GO:0006878,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0019725,GO:0030003,GO:0042221,GO:0042592,GO:0046688,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771		ko:K06201					ko00000				Bacteria	1I1FE@117743,2XK33@283735,4NINY@976,COG3142@1,COG3142@2	NA|NA|NA	P	CutC family
MAG.T21.45_03507	760192.Halhy_4180	8.8e-207	726.5	Sphingobacteriia	PGCP												Bacteria	1INWN@117747,4NE66@976,COG2234@1,COG2234@2	NA|NA|NA	S	Peptidase family M28
MAG.T21.45_03508	760192.Halhy_1931	3.6e-108	398.7	Sphingobacteriia	tolC												Bacteria	1INTW@117747,4NEMI@976,COG1538@1,COG1538@2	NA|NA|NA	MU	PFAM Outer membrane efflux protein
MAG.T21.45_03509	760192.Halhy_1930	0.0	1416.7	Sphingobacteriia	bepE_4			ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718			ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2			Bacteria	1IP63@117747,4NDZG@976,COG0841@1,COG0841@2	NA|NA|NA	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MAG.T21.45_03510	760192.Halhy_1929	9.7e-99	367.1	Sphingobacteriia				ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718			ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6			Bacteria	1IQN0@117747,4NERP@976,COG0845@1,COG0845@2	NA|NA|NA	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAG.T21.45_03511	985255.APHJ01000037_gene2895	3.5e-38	164.5	Gillisia				ko:K13643					ko00000,ko03000				Bacteria	1I1Z9@117743,2P7IM@244698,4NNN2@976,COG1959@1,COG1959@2	NA|NA|NA	K	Transcriptional regulator
MAG.T21.45_03512	760192.Halhy_1810	2.7e-67	262.3	Sphingobacteriia	ytnM			ko:K07090					ko00000				Bacteria	1ISPZ@117747,4PKBI@976,COG0730@1,COG0730@2	NA|NA|NA	S	membrane transporter protein
MAG.T21.45_03513	760192.Halhy_4170	5.3e-109	401.7	Sphingobacteriia													Bacteria	1IQZP@117747,4NGPF@976,COG4704@1,COG4704@2	NA|NA|NA	S	Bacterial Ig-like domain
MAG.T21.45_03514	760192.Halhy_3783	2.5e-222	778.1	Sphingobacteriia	pcd	GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000				Bacteria	1INP0@117747,4NFPJ@976,COG1012@1,COG1012@2	NA|NA|NA	C	Belongs to the aldehyde dehydrogenase family
MAG.T21.45_03515	1122176.KB903541_gene211	4.6e-39	167.5	Sphingobacteriia	yqeY			ko:K09117					ko00000				Bacteria	1IT3W@117747,4NQFI@976,COG1610@1,COG1610@2	NA|NA|NA	S	PFAM Yqey-like protein
MAG.T21.45_03516	760192.Halhy_3322	1.7e-84	319.3	Sphingobacteriia	ksgA	GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363	2.1.1.182	ko:K02528			R10716	RC00003,RC03257	ko00000,ko01000,ko03009				Bacteria	1IR07@117747,4NERB@976,COG0030@1,COG0030@2	NA|NA|NA	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MAG.T21.45_03519	760192.Halhy_2021	1.9e-89	335.9	Bacteroidetes													Bacteria	4NHSE@976,COG1028@1,COG1028@2	NA|NA|NA	IQ	PFAM Short-chain dehydrogenase reductase SDR
MAG.T21.45_03520	760192.Halhy_3399	5e-68	264.6	Sphingobacteriia				ko:K07124					ko00000				Bacteria	1J078@117747,4NKNE@976,COG0300@1,COG0300@2	NA|NA|NA	S	KR domain
MAG.T21.45_03521	760192.Halhy_3400	8.5e-122	444.1	Sphingobacteriia	cap												Bacteria	1IPM6@117747,4NDZ0@976,COG2244@1,COG2244@2	NA|NA|NA	S	Polysaccharide biosynthesis protein
MAG.T21.45_03522	661478.OP10G_2803	5.7e-96	358.2	Bacteria			4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	COG0076@1,COG0076@2	NA|NA|NA	E	glutamate decarboxylase activity
MAG.T21.45_03523	153721.MYP_1114	5.3e-21	106.7	Cytophagia	phhB		4.2.1.96	ko:K01724	ko00790,map00790		R04734	RC01208	ko00000,ko00001,ko01000,ko04147				Bacteria	47RW0@768503,4NS9U@976,COG2154@1,COG2154@2	NA|NA|NA	H	PFAM Pterin 4 alpha carbinolamine dehydratase
MAG.T21.45_03524	760192.Halhy_3120	1.2e-136	493.0	Sphingobacteriia	ybdL	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008483,GO:0010326,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363	2.6.1.17,2.6.1.88	ko:K14267,ko:K14287	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475,R08618	RC00006,RC00025	ko00000,ko00001,ko00002,ko01000,ko01007			iNJ661.Rv0858c	Bacteria	1IP0R@117747,4NES3@976,COG0436@1,COG0436@2	NA|NA|NA	E	PFAM Aminotransferase class I and II
MAG.T21.45_03525	760192.Halhy_2662	1.8e-273	948.3	Sphingobacteriia	purF		2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	1INR4@117747,4NFSM@976,COG0034@1,COG0034@2	NA|NA|NA	F	Amidophosphoribosyltransferase
MAG.T21.45_03527	1122176.KB903548_gene1190	4.5e-186	657.9	Sphingobacteriia	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391		ko:K03572	ko03430,map03430				ko00000,ko00001,ko03400				Bacteria	1IPN2@117747,4NDWJ@976,COG0323@1,COG0323@2	NA|NA|NA	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MAG.T21.45_03528	760192.Halhy_3343	4e-54	218.0	Sphingobacteriia			3.4.21.105	ko:K09650					ko00000,ko01000,ko01002,ko03029				Bacteria	1IYD7@117747,4NIYR@976,COG0705@1,COG0705@2	NA|NA|NA	S	Eukaryotic integral membrane protein (DUF1751)
MAG.T21.45_03529	760192.Halhy_3344	2.6e-68	265.8	Sphingobacteriia													Bacteria	1IS2B@117747,4NGVJ@976,COG0705@1,COG0705@2	NA|NA|NA	S	Rhomboid family
MAG.T21.45_03530	760192.Halhy_3345	9.2e-51	207.6	Sphingobacteriia													Bacteria	1J0X9@117747,4PKDH@976,COG3021@1,COG3021@2	NA|NA|NA	S	Endonuclease/Exonuclease/phosphatase family
MAG.T21.45_03531	760192.Halhy_3346	2.3e-191	675.2	Sphingobacteriia	cysS	GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iECUMN_1333.ECUMN_0566,iJN746.PP_2905,iNJ661.Rv2130c	Bacteria	1INZ2@117747,4NE3Y@976,COG0215@1,COG0215@2	NA|NA|NA	J	Belongs to the class-I aminoacyl-tRNA synthetase family
MAG.T21.45_03532	760192.Halhy_3264	9.9e-30	137.5	Sphingobacteriia	motB			ko:K02557	ko02030,ko02040,map02030,map02040				ko00000,ko00001,ko02000,ko02035	1.A.30.1			Bacteria	1IQDS@117747,4NGHP@976,COG1360@1,COG1360@2	NA|NA|NA	N	OmpA MotB domain protein
MAG.T21.45_03533	760192.Halhy_3265	2.4e-53	216.1	Bacteroidetes	zapB	GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044424,GO:0044444,GO:0044464,GO:0051301	2.1.1.80,3.1.1.61	ko:K09892,ko:K13924	ko02020,ko02030,map02020,map02030	M00506			ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko03036				Bacteria	4NQ7C@976,COG3074@1,COG3074@2	NA|NA|NA	D	FtsZ-dependent cytokinesis
MAG.T21.45_03534	760192.Halhy_5021	0.0	1591.6	Sphingobacteriia				ko:K02014					ko00000,ko02000	1.B.14			Bacteria	1J0SS@117747,4P258@976,COG4206@1,COG4206@2,COG4774@1,COG4774@2	NA|NA|NA	H	TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region
MAG.T21.45_03535	760192.Halhy_5020	1.1e-221	775.8	Sphingobacteriia				ko:K21572					ko00000,ko02000	8.A.46.1,8.A.46.3			Bacteria	1IRA3@117747,28II1@1,2Z8J7@2,4NFJH@976	NA|NA|NA	S	SusD family
MAG.T21.45_03536	1166018.FAES_2905	2.8e-147	528.5	Cytophagia													Bacteria	47JBV@768503,4NHJN@976,COG1680@1,COG1680@2	NA|NA|NA	V	Beta-lactamase
MAG.T21.45_03539	468059.AUHA01000002_gene604	1.4e-31	142.1	Bacteroidetes													Bacteria	294EW@1,2ZRUR@2,4NPA3@976	NA|NA|NA	S	Protein of unknown function (DUF1569)
MAG.T21.45_03540	761193.Runsl_1463	4.4e-56	225.7	Cytophagia													Bacteria	47UTI@768503,4NXWD@976,COG4938@1,COG4938@2	NA|NA|NA	S	AAA ATPase domain
MAG.T21.45_03542	394503.Ccel_2974	5.2e-44	184.9	Clostridia													Bacteria	1VVH5@1239,25176@186801,2E7G4@1,331Z0@2	NA|NA|NA		
MAG.T21.45_03544	373903.Hore_01870	1.3e-36	160.2	Clostridia	lgt_2			ko:K13292					ko00000,ko01000				Bacteria	1TPAK@1239,24BK7@186801,COG0682@1,COG0682@2	NA|NA|NA	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MAG.T21.45_03545	1121288.AULL01000016_gene728	2e-18	97.8	Chryseobacterium													Bacteria	1IHKV@117743,3ZTXU@59732,4NR5F@976,COG1396@1,COG1396@2	NA|NA|NA	K	Helix-turn-helix domain
MAG.T21.45_03546	1121889.AUDM01000004_gene2494	5.6e-146	524.2	Flavobacterium	nhaA			ko:K03313					ko00000,ko02000	2.A.33.1			Bacteria	1HXXZ@117743,2NS9U@237,4NFC4@976,COG3004@1,COG3004@2	NA|NA|NA	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MAG.T21.45_03547	865937.Gilli_1426	3.1e-42	178.3	Flavobacteriia													Bacteria	1I3Q9@117743,2ANDI@1,31DC5@2,4NSSW@976	NA|NA|NA	S	Protein of unknown function (DUF2975)
MAG.T21.45_03548	485918.Cpin_5711	2.9e-26	124.0	Sphingobacteriia	yozG			ko:K07727					ko00000,ko03000				Bacteria	1IT96@117747,4NUP7@976,COG3655@1,COG3655@2	NA|NA|NA	K	Cro/C1-type HTH DNA-binding domain
MAG.T21.45_03549	1123057.P872_13660	1.4e-14	84.7	Cytophagia	fic												Bacteria	47JUU@768503,4NF0H@976,COG3177@1,COG3177@2	NA|NA|NA	S	Domain of unknown function (DUF4172)
MAG.T21.45_03550	1123057.P872_13660	1.8e-19	101.3	Cytophagia	fic												Bacteria	47JUU@768503,4NF0H@976,COG3177@1,COG3177@2	NA|NA|NA	S	Domain of unknown function (DUF4172)
MAG.T21.45_03551	929562.Emtol_1087	3.2e-30	139.4	Cytophagia													Bacteria	47KG1@768503,4NI2T@976,COG3292@1,COG3292@2	NA|NA|NA	T	PFAM Two component regulator propeller
MAG.T21.45_03552	760192.Halhy_3046	5.2e-213	747.3	Bacteroidetes	fadD		6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1			Bacteria	4NFPF@976,COG0318@1,COG0318@2	NA|NA|NA	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II
MAG.T21.45_03553	376686.Fjoh_0466	2.9e-20	104.8	Flavobacterium				ko:K13638,ko:K19591		M00769			ko00000,ko00002,ko01504,ko03000				Bacteria	1I9N7@117743,2NXPU@237,4NZ7Z@976,COG0789@1,COG0789@2	NA|NA|NA	K	MerR, DNA binding
MAG.T21.45_03554	99598.Cal7507_5814	3.8e-92	344.7	Nostocales													Bacteria	1G2X4@1117,1HRY9@1161,COG4221@1,COG4221@2	NA|NA|NA	S	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAG.T21.45_03555	746697.Aeqsu_0197	1.9e-08	65.1	Flavobacteriia													Bacteria	1IABG@117743,2BAT5@1,3248D@2,4P6MV@976	NA|NA|NA		
MAG.T21.45_03556	1122176.KB903543_gene436	5.8e-57	226.9	Sphingobacteriia	sscR		4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016				Bacteria	1IXPD@117747,4NNIS@976,COG0720@1,COG0720@2	NA|NA|NA	H	6-pyruvoyl tetrahydropterin synthase
MAG.T21.45_03557	760192.Halhy_3218	3.4e-77	295.0	Sphingobacteriia	suhB		3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQ46@117747,4NI6D@976,COG0483@1,COG0483@2	NA|NA|NA	G	Inositol monophosphatase
MAG.T21.45_03558	760192.Halhy_3217	1.7e-38	166.0	Sphingobacteriia	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.8,2.7.4.3,6.3.4.19	ko:K00760,ko:K00939,ko:K15780	ko00230,ko00730,ko00983,ko01100,ko01110,ko01130,map00230,map00730,map00983,map01100,map01110,map01130	M00049	R00127,R00190,R01132,R01229,R01547,R02142,R08237,R08238,R08245,R11319	RC00002,RC00063,RC00122	ko00000,ko00001,ko00002,ko01000,ko03016,ko04147			iHN637.CLJU_RS16720	Bacteria	1ISTD@117747,4NNIB@976,COG0634@1,COG0634@2	NA|NA|NA	F	Belongs to the purine pyrimidine phosphoribosyltransferase family
MAG.T21.45_03559	760192.Halhy_3586	1.9e-171	609.0	Sphingobacteriia	pgcp												Bacteria	1IP9S@117747,4NE66@976,COG2234@1,COG2234@2	NA|NA|NA	S	Peptidase family M28
MAG.T21.45_03560	1122176.KB903544_gene751	1.8e-14	85.9	Sphingobacteriia													Bacteria	1ITMC@117747,2DNJW@1,32XVJ@2,4NSCE@976	NA|NA|NA		
MAG.T21.45_03561	760192.Halhy_3966	2.3e-149	535.4	Sphingobacteriia				ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1IR3W@117747,4NEBD@976,COG0577@1,COG0577@2	NA|NA|NA	V	ABC-type antimicrobial peptide transport system, permease component
MAG.T21.45_03562	1122176.KB903550_gene4324	8.8e-63	248.1	Sphingobacteriia													Bacteria	1IUD0@117747,4NPGZ@976,COG2244@1,COG2244@2	NA|NA|NA	S	Polysaccharide biosynthesis C-terminal domain
MAG.T21.45_03563	760192.Halhy_3066	9.5e-62	244.2	Sphingobacteriia			3.1.21.3	ko:K01153,ko:K05789,ko:K07011,ko:K16554	ko05111,map05111				ko00000,ko00001,ko01000,ko01005,ko02000,ko02048	8.A.3.1			Bacteria	1IZTF@117747,4NWAG@976,COG3206@1,COG3206@2	NA|NA|NA	M	Chain length determinant protein
MAG.T21.45_03564	1122176.KB903550_gene4326	6.3e-106	391.3	Bacteroidetes				ko:K16705					ko00000				Bacteria	4NMYT@976,COG3307@1,COG3307@2	NA|NA|NA	M	O-Antigen ligase
MAG.T21.45_03565	1121007.AUML01000003_gene2640	1.1e-16	92.8	Aquimarina	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425		ko:K06199					ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3			Bacteria	1I4DC@117743,2YJRR@290174,4NV3N@976,COG0239@1,COG0239@2	NA|NA|NA	D	CrcB-like protein, Camphor Resistance (CrcB)
MAG.T21.45_03566	1313421.JHBV01000002_gene522	2.2e-87	328.9	Sphingobacteriia	uppS	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.86,2.5.1.88	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110		R06447,R09244,R09731	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006			iLJ478.TM1398	Bacteria	1IPRJ@117747,4NF2B@976,COG0020@1,COG0020@2	NA|NA|NA	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MAG.T21.45_03567	760192.Halhy_3123	0.0	1147.9	Sphingobacteriia	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063		ko:K07277					ko00000,ko02000,ko03029	1.B.33			Bacteria	1IR22@117747,4NE6Z@976,COG4775@1,COG4775@2	NA|NA|NA	M	Outer membrane protein assembly complex, YaeT protein
MAG.T21.45_03568	760192.Halhy_2027	8.9e-109	400.2	Sphingobacteriia	rsgA		3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100		R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009				Bacteria	1IQE6@117747,4NE5H@976,COG1162@1,COG1162@2	NA|NA|NA	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MAG.T21.45_03569	485918.Cpin_0373	1.4e-64	253.1	Sphingobacteriia	pcrB	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576		ko:K07094					ko00000,ko01000				Bacteria	1IW5Q@117747,4NER8@976,COG1646@1,COG1646@2	NA|NA|NA	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)
MAG.T21.45_03570	760192.Halhy_2949	3.1e-37	161.8	Sphingobacteriia	lptC			ko:K09774,ko:K11719					ko00000,ko02000	1.B.42.1			Bacteria	1IU6N@117747,4NV8G@976,COG3117@1,COG3117@2	NA|NA|NA	S	Lipopolysaccharide-assembly, LptC-related
MAG.T21.45_03571	760192.Halhy_2948	4e-259	901.4	Sphingobacteriia			3.2.1.4,5.2.1.8	ko:K01179,ko:K03768,ko:K08738	ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko03110	3.D.4.6	GH5,GH9		Bacteria	1J19E@117747,4NDZC@976,COG3291@1,COG3291@2	NA|NA|NA	S	C-terminal domain of CHU protein family
MAG.T21.45_03572	760192.Halhy_2947	7.8e-49	200.7	Sphingobacteriia	pssA		2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000				Bacteria	1ISNC@117747,4NNUZ@976,COG1183@1,COG1183@2	NA|NA|NA	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MAG.T21.45_03573	1122176.KB903544_gene803	5.8e-23	113.2	Bacteroidetes	purS		6.3.2.6,6.3.5.3	ko:K01923,ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463,R04591	RC00010,RC00064,RC00162,RC01160	ko00000,ko00001,ko00002,ko01000			iYO844.BSU06460	Bacteria	4NV1M@976,COG1828@1,COG1828@2	NA|NA|NA	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MAG.T21.45_03574	760192.Halhy_2945	2e-83	315.5	Sphingobacteriia	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.198	ko:K07056					ko00000,ko01000,ko03009				Bacteria	1IPC1@117747,4NFQM@976,COG0313@1,COG0313@2	NA|NA|NA	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MAG.T21.45_03575	760192.Halhy_3353	9.2e-195	686.4	Sphingobacteriia	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009507,GO:0009536,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0035639,GO:0036094,GO:0036211,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045271,GO:0046390,GO:0046483,GO:0046496,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0070469,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0106077,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147			iE2348C_1286.E2348C_4372,iJN746.PP_4187	Bacteria	1IP5K@117747,4NDVC@976,COG1249@1,COG1249@2	NA|NA|NA	C	Dihydrolipoyl dehydrogenase
MAG.T21.45_03576	1122176.KB903543_gene438	5.1e-133	481.5	Sphingobacteriia	yaaT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464											Bacteria	1IQGD@117747,4NENX@976,COG1774@1,COG1774@2	NA|NA|NA	S	PFAM PSP1 C-terminal conserved region
MAG.T21.45_03577	760192.Halhy_3176	1.1e-94	353.6	Sphingobacteriia	holB		2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1INPG@117747,4NEYF@976,COG0470@1,COG0470@2	NA|NA|NA	L	COG2812 DNA polymerase III, gamma tau subunits
MAG.T21.45_03578	760192.Halhy_3156	0.0	1151.7	Sphingobacteriia	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440		R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400				Bacteria	1IPFU@117747,4NDVA@976,COG0258@1,COG0258@2,COG0749@1,COG0749@2	NA|NA|NA	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MAG.T21.45_03579	760192.Halhy_3088	6.6e-73	281.2	Sphingobacteriia	ydiY			ko:K07283					ko00000				Bacteria	1IPAT@117747,4NGB2@976,COG3137@1,COG3137@2	NA|NA|NA	M	Protein of unknown function (DUF3078)
MAG.T21.45_03580	760192.Halhy_3089	7.5e-54	217.6	Bacteroidetes	cmpX												Bacteria	4NH76@976,COG0668@1,COG0668@2	NA|NA|NA	M	Pfam Mechanosensitive ion channel
MAG.T21.45_03582	760192.Halhy_3091	2.5e-53	215.3	Bacteroidetes	sigX			ko:K03088					ko00000,ko03021				Bacteria	4NNP4@976,COG1595@1,COG1595@2	NA|NA|NA	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family
MAG.T21.45_03584	1280380.KR100_03235	2.4e-33	148.7	Synechococcus	mcrA												Bacteria	1G180@1117,1GYQG@1129,COG1403@1,COG1403@2	NA|NA|NA	L	HNH endonuclease
MAG.T21.45_03586	398720.MED217_13259	8.5e-140	503.8	Leeuwenhoekiella													Bacteria	1HXRM@117743,2XI9Z@283735,4NEN5@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, NAD-binding Rossmann fold
MAG.T21.45_03587	760192.Halhy_5265	3.8e-122	444.5	Sphingobacteriia	mltR												Bacteria	1IVSU@117747,4NGE5@976,COG0662@1,COG0662@2,COG2207@1,COG2207@2	NA|NA|NA	K	helix_turn_helix, arabinose operon control protein
MAG.T21.45_03588	760192.Halhy_5266	4.9e-116	424.1	Sphingobacteriia			5.1.3.30,5.1.3.31	ko:K18910			R10817,R10818	RC03111,RC03283	ko00000,ko01000				Bacteria	1ITB5@117747,4NHGW@976,COG1082@1,COG1082@2	NA|NA|NA	G	PFAM Xylose isomerase-like TIM barrel
MAG.T21.45_03589	760192.Halhy_5267	7.1e-206	723.0	Sphingobacteriia													Bacteria	1IPXS@117747,4NEJM@976,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase
MAG.T21.45_03590	760192.Halhy_5268	0.0	1920.2	Sphingobacteriia				ko:K09992					ko00000				Bacteria	1IVZS@117747,4NFYI@976,COG1413@1,COG1413@2,COG1572@1,COG1572@2,COG2133@1,COG2133@2,COG3241@1,COG3241@2,COG3828@1,COG3828@2	NA|NA|NA	CG	Copper binding proteins, plastocyanin/azurin family
MAG.T21.45_03591	938709.AUSH02000016_gene761	1.7e-120	439.1	Bacteroidetes				ko:K21703,ko:K21711					ko00000,ko03000				Bacteria	4NGHS@976,COG0583@1,COG0583@2	NA|NA|NA	K	LysR substrate binding domain
MAG.T21.45_03593	592029.DDD_3233	1.9e-86	325.9	Flavobacteriia													Bacteria	1HZSU@117743,2DBB9@1,2Z86U@2,4NI91@976	NA|NA|NA		
MAG.T21.45_03594	929703.KE386491_gene1355	3.5e-137	494.6	Cytophagia	sbtA			ko:K07086					ko00000				Bacteria	47JXC@768503,4NIR4@976,COG3329@1,COG3329@2	NA|NA|NA	S	Na+-dependent bicarbonate transporter superfamily
MAG.T21.45_03595	760192.Halhy_1228	2.5e-205	721.8	Sphingobacteriia	mdlA			ko:K06147,ko:K18889	ko02010,map02010	M00707			ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21			Bacteria	1IPDM@117747,4NDY6@976,COG1132@1,COG1132@2	NA|NA|NA	V	ABC transporter
MAG.T21.45_03598	760192.Halhy_4356	1.3e-100	372.9	Sphingobacteriia	murQ		4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100		R08555	RC00397,RC00746	ko00000,ko00001,ko01000				Bacteria	1INX0@117747,4NEPY@976,COG2103@1,COG2103@2	NA|NA|NA	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MAG.T21.45_03599	760192.Halhy_4355	1.4e-55	223.4	Bacteroidetes	gspK	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047931	2.7.1.8	ko:K18676	ko00520,ko01100,map00520,map01100		R01961	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	4NEV4@976,COG2971@1,COG2971@2	NA|NA|NA	G	N-acetylglucosamine kinase
MAG.T21.45_03600	1122176.KB903534_gene2179	1.2e-87	329.7	Sphingobacteriia			3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1IPYC@117747,4NE7U@976,COG1349@1,COG1349@2	NA|NA|NA	K	Bacterial regulatory proteins, deoR family
MAG.T21.45_03601	760192.Halhy_0381	2e-253	882.1	Sphingobacteriia	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576		ko:K04066,ko:K07037,ko:K17266	ko03440,map03440				ko00000,ko00001,ko01000,ko03400,ko04147				Bacteria	1IQGH@117747,4NFHB@976,COG0330@1,COG0330@2,COG1198@1,COG1198@2	NA|NA|NA	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MAG.T21.45_03602	760192.Halhy_4618	7.2e-130	470.7	Bacteroidetes													Bacteria	4PMC8@976,COG3420@1,COG3420@2	NA|NA|NA	CP	Periplasmic copper-binding protein (NosD)
MAG.T21.45_03603	760192.Halhy_4619	1.1e-102	380.2	Sphingobacteriia	MA20_15840												Bacteria	1IQZZ@117747,4NFZJ@976,COG5434@1,COG5434@2	NA|NA|NA	M	Belongs to the glycosyl hydrolase 28 family
MAG.T21.45_03605	760192.Halhy_4621	8.6e-11	72.4	Bacteroidetes													Bacteria	2E715@1,331JW@2,4NZAN@976	NA|NA|NA	S	Domain of unknown function (DUF4177)
MAG.T21.45_03606	760192.Halhy_4622	8.6e-166	590.1	Sphingobacteriia													Bacteria	1IV0D@117747,4NF0F@976,COG0006@1,COG0006@2	NA|NA|NA	E	Metallopeptidase family M24
MAG.T21.45_03607	760192.Halhy_4623	3.4e-89	335.5	Sphingobacteriia													Bacteria	1INWC@117747,4NEUU@976,COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
MAG.T21.45_03608	1121859.KB890757_gene1607	9.7e-95	353.6	Cytophagia	sua5	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566			R10463	RC00745	ko00000,ko01000,ko03009,ko03016				Bacteria	47KX9@768503,4NF5U@976,COG0009@1,COG0009@2	NA|NA|NA	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MAG.T21.45_03609	1150600.ADIARSV_0427	7e-39	167.2	Sphingobacteriia													Bacteria	1J10M@117747,4PKP4@976,COG4319@1,COG4319@2	NA|NA|NA	S	Protein of unknown function (DUF2911)
MAG.T21.45_03611	760192.Halhy_0631	3.8e-110	404.8	Sphingobacteriia	ypdA		1.18.1.2,1.19.1.1,1.8.1.9	ko:K00384,ko:K21567	ko00450,map00450		R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000				Bacteria	1INU1@117747,4NDVS@976,COG0492@1,COG0492@2	NA|NA|NA	O	Pyridine nucleotide-disulphide oxidoreductase
MAG.T21.45_03612	760192.Halhy_0630	1.5e-79	303.1	Sphingobacteriia	idsA		2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006				Bacteria	1INSC@117747,4NEGQ@976,COG0142@1,COG0142@2	NA|NA|NA	H	Belongs to the FPP GGPP synthase family
MAG.T21.45_03613	1313421.JHBV01000004_gene686	5.1e-104	384.8	Sphingobacteriia			3.2.1.78	ko:K19355	ko00051,map00051		R01332	RC00467	ko00000,ko00001,ko01000				Bacteria	1IRN6@117747,4NH10@976,COG3934@1,COG3934@2	NA|NA|NA	G	Cellulase (glycosyl hydrolase family 5)
MAG.T21.45_03614	1123057.P872_19720	8.5e-43	180.3	Cytophagia													Bacteria	47PWB@768503,4NP3F@976,COG2353@1,COG2353@2	NA|NA|NA	S	YceI-like domain
MAG.T21.45_03615	1123057.P872_19715	4.7e-58	231.1	Cytophagia													Bacteria	2CKSA@1,2ZC1U@2,47P79@768503,4NMGH@976	NA|NA|NA		
MAG.T21.45_03616	509635.N824_26310	1.1e-60	240.0	Sphingobacteriia													Bacteria	1IS56@117747,4NNS3@976,COG5587@1,COG5587@2	NA|NA|NA	S	Conserved hypothetical protein (DUF2461)
MAG.T21.45_03617	760192.Halhy_5403	4e-82	311.6	Sphingobacteriia	XK27_04815			ko:K07088					ko00000				Bacteria	1IQQF@117747,4NIQF@976,COG0679@1,COG0679@2	NA|NA|NA	S	Membrane transport protein
MAG.T21.45_03619	1121897.AUGO01000009_gene2904	1e-46	193.7	Flavobacterium													Bacteria	1HYNZ@117743,2NX0F@237,4NR5M@976,COG2197@1,COG2197@2	NA|NA|NA	K	helix_turn_helix, Lux Regulon
MAG.T21.45_03620	925409.KI911562_gene301	1.5e-169	602.8	Sphingobacteriia													Bacteria	1IQ7Y@117747,4NIG6@976,COG1680@1,COG1680@2	NA|NA|NA	V	Beta-lactamase
MAG.T21.45_03621	755732.Fluta_1804	9.9e-97	360.1	Flavobacteriia													Bacteria	1IAY2@117743,4NJXA@976,COG3752@1,COG3752@2	NA|NA|NA	S	Protein of unknown function (DUF1295)
MAG.T21.45_03622	1453498.LG45_09535	3.1e-75	288.5	Flavobacterium													Bacteria	1HXYT@117743,2NVBU@237,4NIC4@976,COG0558@1,COG0558@2	NA|NA|NA	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MAG.T21.45_03623	391598.FBBAL38_00070	5.3e-47	194.9	Flavobacteriia													Bacteria	1IAE5@117743,4NN6R@976,COG2378@1,COG2378@2	NA|NA|NA	K	WYL domain
MAG.T21.45_03624	925409.KI911562_gene2298	3.2e-26	124.8	Sphingobacteriia			1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120		R07177		ko00000,ko00001,ko01000	3.D.4.9			Bacteria	1IU1X@117747,4NX7G@976,COG2146@1,COG2146@2	NA|NA|NA	P	Rieske [2Fe-2S] domain
MAG.T21.45_03625	761193.Runsl_4194	8.3e-77	293.5	Cytophagia			5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000				Bacteria	47NUD@768503,4NK5D@976,COG0135@1,COG0135@2	NA|NA|NA	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
MAG.T21.45_03626	1408473.JHXO01000001_gene1972	0.0	1129.4	Bacteroidia													Bacteria	2FQ0E@200643,4NER2@976,COG2133@1,COG2133@2,COG3391@1,COG3391@2,COG3511@1,COG3511@2	NA|NA|NA	M	Phosphoesterase family
MAG.T21.45_03627	616991.JPOO01000003_gene792	3.1e-146	525.8	Arenibacter				ko:K02014,ko:K16087					ko00000,ko02000	1.B.14,1.B.14.2			Bacteria	1HYJ3@117743,23FMF@178469,4NFZY@976,COG1629@1,COG4771@2	NA|NA|NA	P	TonB dependent receptor
MAG.T21.45_03628	760192.Halhy_0777	1e-196	693.3	Bacteroidetes	dMI1		3.1.4.46	ko:K01126,ko:K10716	ko00564,map00564		R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6			Bacteria	4NMQN@976,COG1226@1,COG1226@2	NA|NA|NA	P	secreted protein
MAG.T21.45_03629	1237149.C900_04215	6.4e-114	417.5	Cytophagia	arsM		2.1.1.137,2.1.1.79	ko:K00574,ko:K07755					ko00000,ko01000				Bacteria	47MVN@768503,4NEUC@976,COG0500@1,COG2226@2	NA|NA|NA	Q	Hypothetical methyltransferase
MAG.T21.45_03630	929703.KE386491_gene3554	9.8e-296	1022.3	Cytophagia	cyt			ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6			Bacteria	47KPY@768503,4NEMM@976,COG2133@1,COG2133@2,COG4654@1,COG4654@2	NA|NA|NA	CG	PFAM Cytochrome c, class I
MAG.T21.45_03631	929703.KE386491_gene3555	1.9e-184	652.5	Cytophagia													Bacteria	47JEV@768503,4NEJ0@976,COG2010@1,COG2010@2	NA|NA|NA	C	Domain of Unknown Function (DUF1080)
MAG.T21.45_03632	1267211.KI669560_gene1020	1.4e-173	616.7	Sphingobacteriia													Bacteria	1IWT6@117747,4NESU@976,COG4447@1,COG4447@2	NA|NA|NA	S	Sortilin, neurotensin receptor 3,
MAG.T21.45_03633	760192.Halhy_4727	1.5e-78	300.4	Sphingobacteriia	ctp		3.4.21.102	ko:K03797					ko00000,ko01000,ko01002				Bacteria	1IP8V@117747,4NEGV@976,COG0793@1,COG0793@2	NA|NA|NA	M	Belongs to the peptidase S41A family
MAG.T21.45_03634	760192.Halhy_4725	1.2e-51	209.5	Sphingobacteriia				ko:K03718					ko00000,ko03000				Bacteria	1J0DI@117747,4NHG9@976,COG1522@1,COG1522@2	NA|NA|NA	K	helix_turn_helix ASNC type
MAG.T21.45_03635	760192.Halhy_4724	2.7e-144	518.1	Sphingobacteriia	rpoD			ko:K03086					ko00000,ko03021				Bacteria	1INNM@117747,4NEBF@976,COG0568@1,COG0568@2	NA|NA|NA	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MAG.T21.45_03636	760192.Halhy_4723	5.4e-33	147.1	Sphingobacteriia													Bacteria	1ISF1@117747,4NNY1@976,COG3832@1,COG3832@2	NA|NA|NA	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein
MAG.T21.45_03637	760192.Halhy_4722	4.7e-155	555.4	Bacteroidetes													Bacteria	4P0HS@976,COG2887@1,COG2887@2	NA|NA|NA	L	Belongs to the helicase family. UvrD subfamily
MAG.T21.45_03638	760192.Halhy_4721	2e-178	633.3	Bacteroidetes			3.2.1.4,5.2.1.8	ko:K01179,ko:K03768,ko:K08738,ko:K13276	ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	3.D.4.6	GH5,GH9		Bacteria	4NVRP@976,COG1404@1,COG1404@2,COG3291@1,COG3291@2	NA|NA|NA	E	Carboxypeptidase
MAG.T21.45_03639	760192.Halhy_0416	3.8e-43	180.6	Sphingobacteriia	fdxB			ko:K04755					ko00000				Bacteria	1IU16@117747,4NQ4P@976,COG0633@1,COG0633@2	NA|NA|NA	C	2Fe-2S iron-sulfur cluster binding domain
MAG.T21.45_03640	760192.Halhy_6292	8.1e-50	203.8	Sphingobacteriia			3.6.1.55	ko:K03574					ko00000,ko01000,ko03400				Bacteria	1ITRK@117747,4NS9I@976,COG1051@1,COG1051@2	NA|NA|NA	F	Belongs to the Nudix hydrolase family
MAG.T21.45_03641	760192.Halhy_6291	4.8e-61	241.1	Sphingobacteriia	pyrE		2.4.2.10,4.1.1.23	ko:K00762,ko:K01591,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000			iYO844.BSU15560	Bacteria	1IPI8@117747,4NEF8@976,COG0461@1,COG0461@2	NA|NA|NA	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MAG.T21.45_03642	1122176.KB903531_gene3118	6.9e-166	590.1	Sphingobacteriia	frvX		3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100		R06200,R11307,R11308		ko00000,ko00001,ko01000		GH5,GH9		Bacteria	1INSP@117747,4NG97@976,COG1363@1,COG1363@2	NA|NA|NA	G	peptidase M42
MAG.T21.45_03643	760192.Halhy_4260	6.2e-86	323.9	Sphingobacteriia				ko:K01463					ko00000,ko01000				Bacteria	1INQT@117747,4NEDJ@976,COG2120@1,COG2120@2	NA|NA|NA	S	GlcNAc-PI de-N-acetylase
MAG.T21.45_03644	760192.Halhy_1263	8.8e-216	756.5	Sphingobacteriia													Bacteria	1IPIC@117747,4NFMV@976,COG1574@1,COG1574@2	NA|NA|NA	S	Amidohydrolase family
MAG.T21.45_03645	760192.Halhy_1262	1.1e-48	199.5	Sphingobacteriia													Bacteria	1J0WI@117747,4NNJS@976,COG0454@1,COG0456@2	NA|NA|NA	K	Acetyltransferase (GNAT) domain
MAG.T21.45_03646	760192.Halhy_4705	4.8e-29	135.6	Sphingobacteriia													Bacteria	1IT7E@117747,4NH7M@976,COG1566@1,COG1566@2	NA|NA|NA	V	Protein of unknown function (DUF3667)
MAG.T21.45_03647	760192.Halhy_4698	6.2e-97	360.9	Sphingobacteriia				ko:K21471					ko00000,ko01000,ko01002,ko01011				Bacteria	1IRSG@117747,4NGHH@976,COG0739@1,COG0739@2	NA|NA|NA	M	PFAM Peptidase family M23
MAG.T21.45_03648	760192.Halhy_4697	0.0	1105.1	Sphingobacteriia	alaS		6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1INPU@117747,4NFHW@976,COG0013@1,COG0013@2	NA|NA|NA	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MAG.T21.45_03649	1492738.FEM21_19540	3.9e-178	631.7	Flavobacterium													Bacteria	1HWZE@117743,2NSQ6@237,4NF11@976,COG0475@1,COG0475@2	NA|NA|NA	PT	Sodium hydrogen exchanger
MAG.T21.45_03650	760192.Halhy_4575	0.0	2365.1	Sphingobacteriia	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400				Bacteria	1IP5J@117747,4NEMW@976,COG0086@1,COG0086@2	NA|NA|NA	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAG.T21.45_03651	760192.Halhy_4574	0.0	2210.3	Sphingobacteriia	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400				Bacteria	1INW0@117747,4NF8D@976,COG0085@1,COG0085@2	NA|NA|NA	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAG.T21.45_03652	1313301.AUGC01000001_gene1760	9.5e-38	162.9	Bacteroidetes	rplL			ko:K02935	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	4NQAQ@976,COG0222@1,COG0222@2	NA|NA|NA	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MAG.T21.45_03653	760192.Halhy_4572	2.6e-57	228.4	Sphingobacteriia	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113		ko:K02864,ko:K02935	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IS1J@117747,4NFFK@976,COG0244@1,COG0244@2	NA|NA|NA	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MAG.T21.45_03654	1122176.KB903532_gene2540	4.3e-95	354.4	Sphingobacteriia	rplA	GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113		ko:K02863	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1IPE4@117747,4NEIC@976,COG0081@1,COG0081@2	NA|NA|NA	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MAG.T21.45_03655	471854.Dfer_3453	3e-62	244.6	Cytophagia	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02867	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	47PEZ@768503,4NM60@976,COG0080@1,COG0080@2	NA|NA|NA	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MAG.T21.45_03656	1122176.KB903532_gene2542	4.4e-76	290.8	Sphingobacteriia	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141		ko:K02601					ko00000,ko03009,ko03021				Bacteria	1INR8@117747,4NF2X@976,COG0250@1,COG0250@2	NA|NA|NA	K	Participates in transcription elongation, termination and antitermination
MAG.T21.45_03658	760192.Halhy_4567	4.3e-193	680.6	Sphingobacteriia	tuf	GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0016020,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484		ko:K02358,ko:K15771	ko02010,map02010	M00491			ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	3.A.1.1.16,3.A.1.1.2		iSB619.SA_RS02960	Bacteria	1IPDP@117747,4NEWS@976,COG0050@1,COG0050@2	NA|NA|NA	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MAG.T21.45_03663	760192.Halhy_4566	7.6e-19	99.8	Sphingobacteriia	hpf			ko:K03733,ko:K05808,ko:K05809					ko00000,ko03009,ko03036				Bacteria	1ITNJ@117747,4NUME@976,COG1544@1,COG1544@2	NA|NA|NA	J	PFAM Sigma 54 modulation protein S30EA ribosomal protein
MAG.T21.45_03664	1123248.KB893314_gene3629	9.1e-66	257.3	Sphingobacteriia	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03733,ko:K04763					ko00000,ko03036				Bacteria	1IP2Y@117747,4NGQW@976,COG4974@1,COG4974@2	NA|NA|NA	L	Belongs to the 'phage' integrase family. XerC subfamily
MAG.T21.45_03665	1123277.KB893174_gene5914	1.6e-12	80.1	Cytophagia													Bacteria	2DBXN@1,2ZBQR@2,47PK0@768503,4NN54@976	NA|NA|NA		
MAG.T21.45_03666	929562.Emtol_3064	2.1e-97	362.8	Cytophagia													Bacteria	47YAI@768503,4PNAP@976,COG0526@1,COG0526@2	NA|NA|NA	CO	Copper type II ascorbate-dependent monooxygenase, C-terminal domain
MAG.T21.45_03667	1185876.BN8_00596	6.5e-20	104.0	Cytophagia													Bacteria	47SBD@768503,4PNAN@976,COG1225@1,COG1225@2	NA|NA|NA	O	AhpC/TSA family
MAG.T21.45_03668	1123278.KB893389_gene4191	4.1e-24	119.0	Cytophagia													Bacteria	28P8P@1,2ZC2K@2,47PHV@768503,4NMXT@976	NA|NA|NA		
MAG.T21.45_03669	929562.Emtol_3062	8.7e-123	447.6	Cytophagia													Bacteria	47M7F@768503,4NFT1@976,COG0521@1,COG0521@2	NA|NA|NA	H	Starch-binding associating with outer membrane
MAG.T21.45_03670	929562.Emtol_3061	0.0	1115.1	Cytophagia													Bacteria	47K6G@768503,4NDU8@976,COG1629@1,COG4771@2	NA|NA|NA	P	PFAM TonB-dependent Receptor Plug
MAG.T21.45_03671	1166018.FAES_4430	1.3e-51	209.5	Cytophagia													Bacteria	2AM3F@1,31BXJ@2,47PK8@768503,4NPAN@976	NA|NA|NA		
MAG.T21.45_03672	1089547.KB913013_gene3676	1.7e-227	795.4	Cytophagia													Bacteria	47M7F@768503,4NFT1@976,COG0521@1,COG0521@2	NA|NA|NA	H	Starch-binding associating with outer membrane
MAG.T21.45_03673	761193.Runsl_1266	0.0	1508.0	Cytophagia													Bacteria	47K6G@768503,4NDU8@976,COG1629@1,COG1629@2,COG4771@2	NA|NA|NA	P	PFAM TonB-dependent Receptor Plug
MAG.T21.45_03674	760192.Halhy_4553	1.4e-60	239.6	Sphingobacteriia	psd		4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000				Bacteria	1INZC@117747,4NFU1@976,COG0688@1,COG0688@2	NA|NA|NA	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MAG.T21.45_03675	1122179.KB890432_gene4128	3.7e-47	195.3	Sphingobacteriia	cdsA		2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	1IQW1@117747,4NIPM@976,COG4589@1,COG4589@2	NA|NA|NA	S	Belongs to the CDS family
MAG.T21.45_03676	1122176.KB903547_gene1084	5.1e-34	151.8	Sphingobacteriia				ko:K07052					ko00000				Bacteria	1IT2K@117747,4NHE1@976,COG1266@1,COG1266@2	NA|NA|NA	S	CAAX amino terminal protease family
MAG.T21.45_03677	153721.MYP_4840	3.8e-80	304.7	Cytophagia	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000				Bacteria	47K7U@768503,4NF4Z@976,COG0854@1,COG0854@2	NA|NA|NA	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MAG.T21.45_03678	760192.Halhy_1170	0.0	1112.1	Sphingobacteriia	glgP		2.4.1.1,2.4.1.11,2.4.1.8	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931		R00292,R01555,R02111	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003		GH65,GT3,GT35		Bacteria	1IPKK@117747,4NGR1@976,COG0058@1,COG0058@2	NA|NA|NA	G	COGs COG0058 Glucan phosphorylase
MAG.T21.45_03679	760192.Halhy_1167	8.3e-212	743.0	Sphingobacteriia	lysA		4.1.1.19,4.1.1.20	ko:K01585,ko:K01586	ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00133,M00525,M00526,M00527	R00451,R00566	RC00299	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS18870	Bacteria	1IQUN@117747,4NFHV@976,COG0019@1,COG0019@2	NA|NA|NA	E	decarboxylase
MAG.T21.45_03681	1499967.BAYZ01000033_gene1097	1.6e-241	843.2	unclassified Bacteria			2.1.1.72	ko:K07317					ko00000,ko01000,ko02048				Bacteria	2NNXD@2323,COG0827@1,COG0827@2,COG1002@1,COG1002@2	NA|NA|NA	LV	Eco57I restriction-modification methylase
MAG.T21.45_03682	700598.Niako_1487	4e-105	388.3	Bacteroidetes													Bacteria	4NE0Q@976,COG4804@1,COG4804@2	NA|NA|NA	S	Psort location Cytoplasmic, score 8.96
MAG.T21.45_03683	888059.HMPREF9071_1750	4.6e-309	1067.4	Capnocytophaga													Bacteria	1ER99@1016,1HZ1X@117743,4NH3B@976,COG0553@1,COG0553@2	NA|NA|NA	KL	helicase
MAG.T21.45_03684	714943.Mucpa_2716	8.3e-167	594.0	Sphingobacteriia													Bacteria	1IQ1V@117747,4PMBP@976,COG0644@1,COG0644@2	NA|NA|NA	C	FAD dependent oxidoreductase
MAG.T21.45_03685	1296416.JACB01000001_gene3228	1e-246	859.4	Aquimarina													Bacteria	1HWTC@117743,2YIR0@290174,4PKHI@976,COG0591@1,COG0591@2	NA|NA|NA	E	Sodium:solute symporter family
MAG.T21.45_03686	929556.Solca_2698	3.5e-126	458.0	Sphingobacteriia													Bacteria	1IQJ4@117747,2DB9J@1,2Z7X1@2,4NGUY@976	NA|NA|NA	S	Domain of unknown function (DUF5109)
MAG.T21.45_03687	562970.Btus_3148	4.4e-11	73.9	Bacilli				ko:K07076					ko00000				Bacteria	1VF20@1239,4HP2A@91061,COG1708@1,COG1708@2	NA|NA|NA	S	Nucleotidyltransferase domain
MAG.T21.45_03689	700598.Niako_3218	5e-130	471.1	Sphingobacteriia													Bacteria	1INR1@117747,28HII@1,2Z7TZ@2,4NHR6@976	NA|NA|NA		
MAG.T21.45_03690	468059.AUHA01000005_gene2428	1.1e-138	500.0	Sphingobacteriia													Bacteria	1IV7P@117747,2CA5R@1,2Z81H@2,4NGSF@976	NA|NA|NA		
MAG.T21.45_03691	1121904.ARBP01000006_gene3923	1.3e-26	125.6	Cytophagia	MA20_23570			ko:K03892					ko00000,ko03000				Bacteria	47R9V@768503,4NSAV@976,COG0640@1,COG0640@2	NA|NA|NA	K	Winged helix DNA-binding domain
MAG.T21.45_03692	1124780.ANNU01000008_gene2712	1.9e-51	209.1	Cytophagia				ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	47P7G@768503,4NN8S@976,COG3127@1,COG3127@2	NA|NA|NA	Q	membrane
MAG.T21.45_03693	929562.Emtol_0414	3.5e-245	854.4	Cytophagia													Bacteria	47J9H@768503,4NG6C@976,COG4225@1,COG4225@2	NA|NA|NA	S	Heparinase II/III-like protein
MAG.T21.45_03694	761193.Runsl_4222	1.8e-136	492.3	Cytophagia													Bacteria	47YFZ@768503,4PNXV@976,COG2152@1,COG2152@2	NA|NA|NA	G	Glycosyl hydrolases family 32 N-terminal domain
MAG.T21.45_03695	929562.Emtol_0416	1.3e-220	772.7	Cytophagia													Bacteria	47K76@768503,4NF1N@976,COG4225@1,COG4225@2	NA|NA|NA	S	Heparinase II/III-like protein
MAG.T21.45_03696	761193.Runsl_0424	7.2e-216	756.9	Cytophagia													Bacteria	47K76@768503,4NF1N@976,COG4225@1,COG4225@2	NA|NA|NA	S	Heparinase II/III-like protein
MAG.T21.45_03697	929562.Emtol_0417	6.8e-250	869.8	Cytophagia													Bacteria	47K08@768503,4NDX0@976,COG0457@1,COG0457@2	NA|NA|NA	S	SusD family
MAG.T21.45_03698	929562.Emtol_0418	0.0	1516.1	Cytophagia													Bacteria	47JJX@768503,4NDXS@976,COG1629@1,COG1629@2	NA|NA|NA	P	TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region
MAG.T21.45_03699	1121904.ARBP01000017_gene5136	8.3e-147	526.6	Cytophagia													Bacteria	47N28@768503,4NG3B@976,COG5285@1,COG5285@2	NA|NA|NA	Q	Phytanoyl-CoA dioxygenase (PhyH)
MAG.T21.45_03700	641524.ADICYQ_3983	7.2e-67	260.0	Cytophagia	dps	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0042262,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360		ko:K04047					ko00000,ko03036				Bacteria	47QGP@768503,4NQDD@976,COG0783@1,COG0783@2	NA|NA|NA	P	Belongs to the Dps family
MAG.T21.45_03701	376686.Fjoh_3327	4.6e-103	380.9	Flavobacterium			1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000				Bacteria	1I01I@117743,2NUD8@237,4NJJI@976,COG0289@1,COG0289@2	NA|NA|NA	E	Belongs to the DapB family
MAG.T21.45_03702	929562.Emtol_2881	1.6e-123	449.5	Cytophagia	cdu2												Bacteria	47NVA@768503,4NK07@976,COG0025@1,COG0025@2	NA|NA|NA	P	PFAM sodium hydrogen exchanger
MAG.T21.45_03703	1239962.C943_00430	5.7e-151	540.8	Cytophagia	gbpD												Bacteria	47NYM@768503,4PJN0@976,COG4099@1,COG4099@2	NA|NA|NA	S	Phospholipase/Carboxylesterase
MAG.T21.45_03704	1313421.JHBV01000009_gene4137	3.4e-165	588.2	Bacteroidetes	femD		5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000				Bacteria	4NFU7@976,COG1109@1,COG1109@2	NA|NA|NA	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II
MAG.T21.45_03705	760192.Halhy_1273	9.9e-67	260.0	Sphingobacteriia	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573					ko00000,ko01000				Bacteria	1IQ1X@117747,4NFCU@976,COG2518@1,COG2518@2	NA|NA|NA	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MAG.T21.45_03706	1122179.KB890414_gene1740	7.3e-53	213.4	Sphingobacteriia	tadA	GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360	3.4.17.13,3.5.4.1,3.5.4.3,3.5.4.33,3.8.1.5,6.3.4.19	ko:K01297,ko:K01485,ko:K01487,ko:K01563,ko:K04075,ko:K11991	ko00230,ko00240,ko00330,ko00361,ko00625,ko01100,ko01120,map00230,map00240,map00330,map00361,map00625,map01100,map01120		R00974,R01411,R01676,R02922,R05284,R05367,R05368,R05369,R05370,R07669,R07670,R09597,R10223	RC00074,RC00204,RC00477,RC00514,RC00809,RC01317,RC01340,RC01341,RC02013,RC02633,RC02634	ko00000,ko00001,ko01000,ko01002,ko01011,ko03016				Bacteria	1ISDN@117747,4NNJ2@976,COG0590@1,COG0590@2	NA|NA|NA	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MAG.T21.45_03707	760192.Halhy_1322	1.1e-217	762.7	Sphingobacteriia	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147			iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027	Bacteria	1IPBW@117747,4NDXQ@976,COG0516@1,COG0516@2,COG0517@1,COG0517@2	NA|NA|NA	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MAG.T21.45_03708	1122176.KB903540_gene54	1.2e-87	330.5	Sphingobacteriia													Bacteria	1INW8@117747,28HE2@1,2Z7QJ@2,4NFBA@976	NA|NA|NA	S	Domain of unknown function (DUF5103)
MAG.T21.45_03709	760192.Halhy_1268	1e-116	427.2	Sphingobacteriia				ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821			ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2			Bacteria	1IP2E@117747,4NEEN@976,COG1538@1,COG1538@2	NA|NA|NA	MU	outer membrane efflux protein
MAG.T21.45_03710	760192.Halhy_1269	3.8e-132	478.4	Sphingobacteriia	macA			ko:K02005					ko00000				Bacteria	1IRGW@117747,4NFT4@976,COG0845@1,COG0845@2	NA|NA|NA	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAG.T21.45_03711	760192.Halhy_1270	4.9e-36	157.9	Sphingobacteriia				ko:K09931					ko00000				Bacteria	1IXRU@117747,4NM7F@976,COG3222@1,COG3222@2	NA|NA|NA	S	Guanylyl transferase CofC like
MAG.T21.45_03713	760192.Halhy_1313	1.8e-50	205.3	Sphingobacteriia	yqiW												Bacteria	1ISFT@117747,28NYH@1,2ZBVN@2,4NMB2@976	NA|NA|NA	S	Belongs to the UPF0403 family
MAG.T21.45_03714	1270196.JCKI01000004_gene1116	5.4e-65	254.2	Sphingobacteriia	pdxH	GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000				Bacteria	1IRWF@117747,4NFH7@976,COG0259@1,COG0259@2	NA|NA|NA	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
MAG.T21.45_03715	1122176.KB903543_gene452	4.1e-61	241.5	Sphingobacteriia													Bacteria	1IXS1@117747,2C8XG@1,2Z7PK@2,4NEU8@976	NA|NA|NA	S	Protein of unknown function (DUF4197)
MAG.T21.45_03716	504472.Slin_5706	1e-119	436.8	Cytophagia	dmpA		3.4.11.19	ko:K01266					ko00000,ko01000,ko01002				Bacteria	47K9S@768503,4NGDT@976,COG3191@1,COG3191@2	NA|NA|NA	EQ	Peptidase family S58
MAG.T21.45_03717	491205.JARQ01000002_gene80	6.3e-31	141.0	Chryseobacterium	pucB		1.1.1.328,1.17.1.4,2.7.7.76	ko:K00087,ko:K07141,ko:K07402,ko:K19190	ko00230,ko00760,ko00790,ko01100,ko01120,map00230,map00760,map00790,map01100,map01120	M00546	R01768,R02103,R10131,R10132,R11582	RC00143,RC03053	ko00000,ko00001,ko00002,ko01000				Bacteria	1I2S6@117743,3ZTUQ@59732,4NQNF@976,COG2068@1,COG2068@2	NA|NA|NA	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
MAG.T21.45_03718	760192.Halhy_4690	8.6e-62	244.2	Sphingobacteriia	yfiM			ko:K05811					ko00000				Bacteria	1IXKD@117747,4NGNB@976,COG5544@1,COG5544@2	NA|NA|NA	S	Predicted periplasmic lipoprotein (DUF2279)
MAG.T21.45_03719	1124780.ANNU01000073_gene711	1.9e-68	266.2	Cytophagia	rimK	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564	6.3.1.17,6.3.2.32,6.3.2.41	ko:K05844,ko:K14940,ko:K18310	ko00250,ko00680,ko01100,ko01120,map00250,map00680,map01100,map01120		R09401,R10677,R10678	RC00064,RC00090,RC00141,RC03233	ko00000,ko00001,ko01000,ko03009				Bacteria	47KJX@768503,4NED4@976,COG0189@1,COG0189@2	NA|NA|NA	HJ	Belongs to the RimK family
MAG.T21.45_03720	1122176.KB903554_gene3852	1.4e-117	429.9	Sphingobacteriia	yxiO			ko:K06902	ko04138,map04138				ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1			Bacteria	1INX9@117747,4NEKI@976,COG2270@1,COG2270@2	NA|NA|NA	S	COGs COG2270 Permease of the major facilitator superfamily
MAG.T21.45_03721	926549.KI421517_gene1122	8.7e-69	267.7	Cytophagia													Bacteria	28I3N@1,2Z87C@2,47M50@768503,4NE8P@976	NA|NA|NA	S	Domain of unknown function (DUF4105)
MAG.T21.45_03722	1034807.FBFL15_0522	1.1e-92	346.7	Bacteroidetes													Bacteria	2DZSH@1,32VHS@2,4NYRA@976	NA|NA|NA	S	to other proteins from the same organism
MAG.T21.45_03723	760192.Halhy_5090	1.1e-65	256.5	Sphingobacteriia			3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120		R05287	RC00697	ko00000,ko00001,ko01000				Bacteria	1IPZN@117747,4NIMR@976,COG1011@1,COG1011@2	NA|NA|NA	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3
MAG.T21.45_03724	925409.KI911562_gene59	8e-166	590.1	Sphingobacteriia	gltP			ko:K03309,ko:K11102					ko00000,ko02000	2.A.23,2.A.23.1.1,2.A.23.1.2			Bacteria	1INWV@117747,4NDUU@976,COG1301@1,COG1301@2	NA|NA|NA	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MAG.T21.45_03726	760192.Halhy_1461	0.0	1701.4	Sphingobacteriia	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1IR52@117747,4NFA0@976,COG0587@1,COG0587@2	NA|NA|NA	L	DNA polymerase III alpha subunit
MAG.T21.45_03727	1123277.KB893239_gene1211	1.9e-122	446.8	Cytophagia													Bacteria	47P4Q@768503,4NG07@976,COG4886@1,COG4886@2	NA|NA|NA	S	Chitobiase/beta-hexosaminidase C-terminal domain
MAG.T21.45_03728	929562.Emtol_2258	3.1e-222	777.7	Cytophagia													Bacteria	47KYW@768503,4NE73@976,COG4102@1,COG4102@2	NA|NA|NA	S	Protein of unknown function (DUF1501)
MAG.T21.45_03729	1089547.KB913013_gene4651	2.4e-280	971.5	Cytophagia													Bacteria	47P04@768503,4NEPV@976,COG2010@1,COG2010@2	NA|NA|NA	C	Protein of unknown function (DUF1549)
MAG.T21.45_03730	760192.Halhy_4790	8.9e-69	268.9	Sphingobacteriia	zraS_1												Bacteria	1INZH@117747,4NE49@976,COG5000@1,COG5000@2	NA|NA|NA	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MAG.T21.45_03731	760192.Halhy_4788	2.3e-180	638.6	Sphingobacteriia	crtD		1.3.99.26,1.3.99.27,1.3.99.28,1.3.99.29,1.3.99.31,5.4.99.9	ko:K01854,ko:K09845,ko:K10027	ko00052,ko00520,ko00906,ko01100,ko01110,map00052,map00520,map00906,map01100,map01110		R00505,R04787,R04798,R04800,R07517,R07520,R07523,R07534,R09009,R09691,R09692	RC00317,RC01214,RC02080,RC02088,RC02396,RC02605	ko00000,ko00001,ko01000				Bacteria	1IR1U@117747,4NG7V@976,COG1233@1,COG1233@2	NA|NA|NA	Q	Flavin containing amine oxidoreductase
MAG.T21.45_03732	760192.Halhy_4786	3e-57	228.0	Sphingobacteriia	crtZ		1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000				Bacteria	1ISJ5@117747,4NMA9@976,COG3000@1,COG3000@2	NA|NA|NA	I	Beta-carotene hydroxylase
MAG.T21.45_03734	760192.Halhy_4437	2.1e-185	655.2	Sphingobacteriia	nqrF		1.6.5.8	ko:K00351					ko00000,ko01000				Bacteria	1J0XH@117747,4NFKC@976,COG2871@1,COG2871@2	NA|NA|NA	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway
MAG.T21.45_03735	1122176.KB903545_gene939	2.9e-81	308.1	Bacteroidetes	nqrE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494	1.6.5.8	ko:K00350					ko00000,ko01000				Bacteria	4NEU0@976,COG2209@1,COG2209@2	NA|NA|NA	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MAG.T21.45_03736	1122176.KB903545_gene938	2.2e-88	332.0	Bacteroidetes	nqrD	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.6.5.8	ko:K00349					ko00000,ko01000				Bacteria	4NGD9@976,COG1347@1,COG1347@2	NA|NA|NA	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MAG.T21.45_03737	1122176.KB903545_gene937	1e-77	296.6	Bacteroidetes	nqrC	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363	1.6.5.8	ko:K00348					ko00000,ko01000				Bacteria	4NF7A@976,COG2869@1,COG2869@2	NA|NA|NA	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MAG.T21.45_03738	760192.Halhy_4433	4.8e-174	617.5	Bacteroidetes	nqrB		1.6.5.8	ko:K00347					ko00000,ko01000				Bacteria	4NFGW@976,COG4658@1,COG4658@2	NA|NA|NA	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MAG.T21.45_03739	1122176.KB903545_gene935	2.5e-151	542.3	Bacteroidetes	nqrA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494	1.6.5.8	ko:K00346					ko00000,ko01000				Bacteria	4NEDQ@976,COG1726@1,COG1726@2	NA|NA|NA	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MAG.T21.45_03740	760192.Halhy_1699	1.3e-234	819.7	Sphingobacteriia													Bacteria	1IPTT@117747,4NE6G@976,COG0457@1,COG0457@2,COG2885@1,COG2885@2	NA|NA|NA	M	OmpA MotB domain protein
MAG.T21.45_03741	1122176.KB903534_gene2217	2.8e-69	269.2	Bacteria				ko:K06076					ko00000,ko02000	1.B.9			Bacteria	COG2067@1,COG2067@2	NA|NA|NA	I	long-chain fatty acid transporting porin activity
MAG.T21.45_03742	760192.Halhy_1701	5.6e-77	294.7	Sphingobacteriia				ko:K02843	ko00540,ko01100,map00540,map01100	M00080			ko00000,ko00001,ko00002,ko01000,ko01003,ko01005		GT9		Bacteria	1INZA@117747,4NEPH@976,COG0859@1,COG0859@2	NA|NA|NA	M	Glycosyl transferase, family 9
MAG.T21.45_03743	1122176.KB903535_gene2005	4.3e-144	518.1	Bacteroidetes	phoD		3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	4NDUS@976,COG3540@1,COG3540@2	NA|NA|NA	P	COG3540 Phosphodiesterase alkaline phosphatase D
MAG.T21.45_03744	760192.Halhy_1702	2.1e-46	192.6	Bacteroidetes				ko:K07452					ko00000,ko01000,ko02048				Bacteria	4P8RG@976,COG5036@1,COG5036@2	NA|NA|NA	P	VTC domain
MAG.T21.45_03745	1122225.AULQ01000002_gene493	1.4e-110	406.4	Flavobacteriia	tas	GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928											Bacteria	1HY7T@117743,4NEDK@976,COG0667@1,COG0667@2	NA|NA|NA	C	aldo keto reductase
MAG.T21.45_03747	1122176.KB903542_gene299	1e-125	456.8	Sphingobacteriia	deaD												Bacteria	1IR44@117747,4NEVI@976,COG0513@1,COG0513@2	NA|NA|NA	L	Belongs to the DEAD box helicase family
MAG.T21.45_03748	926549.KI421517_gene793	2.7e-168	599.4	Cytophagia			2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501				ko00000,ko00001,ko01000,ko01003,ko01011		GT51		Bacteria	47MZQ@768503,4NECJ@976,COG5009@1,COG5009@2	NA|NA|NA	M	Transglycosylase
MAG.T21.45_03749	760192.Halhy_1686	1.8e-45	189.1	Sphingobacteriia	nudF												Bacteria	1IS81@117747,4NNGW@976,COG0494@1,COG0494@2	NA|NA|NA	L	pfam nudix
MAG.T21.45_03750	760192.Halhy_1685	7.5e-63	246.9	Sphingobacteriia				ko:K03088					ko00000,ko03021				Bacteria	1ISH7@117747,4NQCH@976,COG1595@1,COG1595@2	NA|NA|NA	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MAG.T21.45_03751	760192.Halhy_1684	3.3e-31	142.9	Sphingobacteriia													Bacteria	1J01W@117747,2CI2X@1,2ZR94@2,4P8NA@976	NA|NA|NA		
MAG.T21.45_03752	485918.Cpin_1991	1.3e-38	165.6	Sphingobacteriia			5.1.3.32	ko:K03534			R10819	RC00563	ko00000,ko01000				Bacteria	1ISWR@117747,4NQAA@976,COG3254@1,COG3254@2	NA|NA|NA	S	PFAM Rhamnose mutarotase
MAG.T21.45_03753	925409.KI911562_gene35	4.2e-86	324.7	Sphingobacteriia				ko:K07046	ko00051,ko01120,map00051,map01120		R10689	RC00537	ko00000,ko00001,ko01000				Bacteria	1INSJ@117747,4NFGB@976,COG3618@1,COG3618@2	NA|NA|NA	S	PFAM amidohydrolase
MAG.T21.45_03754	760192.Halhy_3450	1.7e-161	576.2	Sphingobacteriia													Bacteria	1IQ63@117747,4NFKQ@976,COG1649@1,COG1649@2	NA|NA|NA	F	Glycosyl hydrolase-like 10
MAG.T21.45_03755	760192.Halhy_3562	3.9e-109	401.4	Sphingobacteriia	lolI		5.3.99.11	ko:K06606	ko00562,ko01120,map00562,map01120		R09952	RC01513	ko00000,ko00001,ko01000				Bacteria	1ITFA@117747,4NEUS@976,COG1082@1,COG1082@2	NA|NA|NA	G	Xylose isomerase-like TIM barrel
MAG.T21.45_03758	1089547.KB913013_gene3920	1.2e-10	74.7	Cytophagia													Bacteria	2C2U1@1,2Z959@2,47MZ8@768503,4NGGF@976	NA|NA|NA		
MAG.T21.45_03760	1131812.JQMS01000001_gene1156	4.3e-19	103.2	Flavobacteriia													Bacteria	1IA2A@117743,2C2FV@1,337CM@2,4NX2Z@976	NA|NA|NA		
MAG.T21.45_03762	929703.KE386491_gene3160	7.2e-150	537.3	Cytophagia	aldH		1.2.1.26,1.2.1.4	ko:K13877,ko:K14519	ko00040,ko00053,ko00930,ko01100,ko01120,ko01220,map00040,map00053,map00930,map01100,map01120,map01220		R00264,R05099	RC00080	ko00000,ko00001,ko01000				Bacteria	47MQT@768503,4NEKG@976,COG1012@1,COG1012@2	NA|NA|NA	C	PFAM Aldehyde dehydrogenase
MAG.T21.45_03763	929562.Emtol_2268	1.6e-136	492.3	Cytophagia	kdgD		4.2.1.41	ko:K01707	ko00053,ko01100,map00053,map01100		R02279	RC00678	ko00000,ko00001,ko01000				Bacteria	47KI9@768503,4NHBA@976,COG0329@1,COG0329@2	NA|NA|NA	EM	Belongs to the DapA family
MAG.T21.45_03764	761193.Runsl_1200	7.7e-168	596.7	Cytophagia	uxuA		4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000				Bacteria	47JVK@768503,4NIMS@976,COG1312@1,COG1312@2	NA|NA|NA	G	D-mannonate dehydratase (UxuA)
MAG.T21.45_03765	761193.Runsl_1197	1.2e-213	749.2	Cytophagia	gntP			ko:K03299					ko00000,ko02000	2.A.8			Bacteria	47K2S@768503,4NJ5B@976,COG2610@1,COG2610@2	NA|NA|NA	EG	PFAM Gluconate transporter
MAG.T21.45_03766	929562.Emtol_2267	1.7e-214	751.9	Cytophagia	gudD		4.2.1.40	ko:K01706	ko00053,ko01100,map00053,map01100		R02752,R08056	RC00543	ko00000,ko00001,ko01000				Bacteria	47KJ8@768503,4NFHR@976,COG4948@1,COG4948@2	NA|NA|NA	M	PFAM Mandelate racemase muconate lactonizing
MAG.T21.45_03767	1185876.BN8_03568	1.3e-207	729.2	Cytophagia													Bacteria	47JMV@768503,4PKAT@976,COG0521@1,COG0521@2	NA|NA|NA	H	Starch-binding associating with outer membrane
MAG.T21.45_03768	1185876.BN8_03569	0.0	1537.3	Cytophagia													Bacteria	47MNM@768503,4PKAS@976,COG1629@1,COG1629@2	NA|NA|NA	P	Carboxypeptidase regulatory-like domain
MAG.T21.45_03769	761193.Runsl_0419	5.1e-100	371.3	Cytophagia													Bacteria	47MG6@768503,4NKZC@976,COG3712@1,COG3712@2	NA|NA|NA	PT	Domain of unknown function (DUF4974)
MAG.T21.45_03770	1185876.BN8_00152	3.5e-58	231.5	Cytophagia				ko:K03088					ko00000,ko03021				Bacteria	47PHA@768503,4NMEC@976,COG1595@1,COG1595@2	NA|NA|NA	K	Sigma-70, region 4
MAG.T21.45_03771	1450525.JATV01000006_gene1138	7.8e-99	367.1	Flavobacterium	corA			ko:K03284					ko00000,ko02000	1.A.35.1,1.A.35.3			Bacteria	1HXRX@117743,2NVAM@237,4NG3C@976,COG0598@1,COG0598@2	NA|NA|NA	P	CorA-like Mg2+ transporter protein
MAG.T21.45_03772	761193.Runsl_2719	2.7e-39	167.9	Cytophagia													Bacteria	47RTH@768503,4NQ5C@976,COG1733@1,COG1733@2	NA|NA|NA	K	HxlR-like helix-turn-helix
MAG.T21.45_03773	761193.Runsl_2718	3.8e-156	557.8	Cytophagia				ko:K10680	ko00633,ko01120,map00633,map01120		R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000				Bacteria	47M7J@768503,4NF98@976,COG1902@1,COG1902@2	NA|NA|NA	C	PFAM NADH flavin oxidoreductase NADH oxidase
MAG.T21.45_03774	1034807.FBFL15_3069	3.8e-39	167.5	Bacteria													Bacteria	COG3795@1,COG3795@2	NA|NA|NA	F	YCII-related domain
MAG.T21.45_03775	761193.Runsl_2717	1.5e-24	118.6	Cytophagia			5.3.3.4	ko:K03464	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R06990	RC01109	ko00000,ko00001,ko00002,ko01000				Bacteria	2EGEP@1,33A6N@2,47T7P@768503,4NXT1@976	NA|NA|NA		
MAG.T21.45_03776	694427.Palpr_3004	9.8e-26	122.5	Bacteroidia				ko:K06218,ko:K07334					ko00000,ko02048				Bacteria	2FW0W@200643,4PA2F@976,COG2026@1,COG2026@2	NA|NA|NA	DJ	Addiction module toxin, RelE StbE family
MAG.T21.45_03778	694427.Palpr_3005	3.5e-90	338.2	Bacteroidetes	gepA												Bacteria	4NN94@976,COG1476@1,COG1476@2,COG3600@1,COG3600@2	NA|NA|NA	K	Protein of unknown function (DUF4065)
MAG.T21.45_03779	946483.Cenrod_0576	1.4e-36	159.8	Betaproteobacteria													Bacteria	1R4NN@1224,2VXID@28216,COG1672@1,COG1672@2	NA|NA|NA	S	PFAM Archaeal ATPase
MAG.T21.45_03780	765911.Thivi_3887	4.3e-51	208.4	Chromatiales													Bacteria	1R4NN@1224,1RMA8@1236,1WXX1@135613,COG1672@1,COG1672@2	NA|NA|NA	S	PFAM Archaeal ATPase
MAG.T21.45_03781	761193.Runsl_1740	3.8e-179	634.4	Cytophagia	axe7A												Bacteria	47MHG@768503,4NGH5@976,COG3458@1,COG3458@2	NA|NA|NA	Q	PFAM Acetyl xylan esterase
MAG.T21.45_03782	1131812.JQMS01000001_gene2726	3e-233	815.8	Flavobacterium				ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100				ko00000,ko00001				Bacteria	1IJ7S@117743,2P0VG@237,4PKBQ@976,COG1470@1,COG1470@2,COG2304@1,COG2304@2,COG3209@1,COG3209@2,COG3391@1,COG3391@2	NA|NA|NA	M	C-terminal domain of CHU protein family
MAG.T21.45_03783	694427.Palpr_0095	2.3e-186	661.0	Bacteroidetes				ko:K12287					ko00000,ko02044				Bacteria	4NS69@976,COG1357@1,COG1357@2,COG1404@1,COG1404@2,COG3291@1,COG3291@2	NA|NA|NA	O	C-terminal domain of CHU protein family
MAG.T21.45_03784	1041826.FCOL_02190	1.5e-27	129.4	Flavobacterium	yneE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K08994					ko00000,ko02000	1.A.46.2			Bacteria	1HYDP@117743,2NSGY@237,4NEB1@976,COG3781@1,COG3781@2	NA|NA|NA	S	membrane
# 3361 queries scanned
# Total time (seconds): 6.08497905731
# Rate: 552.34 q/s