# emapper version: emapper-2.0.1 emapper DB: 2.0 # command: ./emapper.py -m diamond --seed_ortholog_evalue 0.00001 --data_dir /home/bayegy/Databases/emapper/data_dir2.0.1/ --cpu 30 --temp_dir /media/bayegy/disk2/bayegy/pipeline_demos/binning/share2/Bin_all/emapper//MAG.T22.3/_tmp -i /media/bayegy/disk2/bayegy/pipeline_demos/binning/share2/Bin_all/Bin_prokka//MAG.T22.3/MAG.T22.3.faa -o /media/bayegy/disk2/bayegy/pipeline_demos/binning/share2/Bin_all/emapper//MAG.T22.3/MAG.T22.3 --usemem --override # time: Wed Feb 25 23:47:27 2026 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction taxonomic scope eggNOG OGs best eggNOG OG COG Functional cat. eggNOG free text desc. MAG.T22.3_00001 1239962.C943_04061 1.1e-99 369.4 Cytophagia Bacteria 47S60@768503,4NVYW@976,COG0457@1,COG0457@2 NA|NA|NA S Protein of unknown function (DUF2911) MAG.T22.3_00002 1239962.C943_04062 0.0 8918.5 Cytophagia Bacteria 47JBY@768503,4NDV5@976,COG1020@1,COG1020@2 NA|NA|NA Q Amino acid adenylation domain MAG.T22.3_00003 1239962.C943_04063 5.6e-127 460.3 Cytophagia acpT GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006553,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0019878,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.8.7 ko:K00997,ko:K06133 ko00770,map00770 R01625 RC00002 ko00000,ko00001,ko01000 iECNA114_1301.ECNA114_3584 Bacteria 47S70@768503,4NSR9@976,COG2091@1,COG2091@2 NA|NA|NA H 4'-phosphopantetheinyl transferase superfamily MAG.T22.3_00005 1239962.C943_04065 3.7e-260 903.7 Cytophagia ko:K03457 ko00000 2.A.39 Bacteria 47KQF@768503,4NHHC@976,COG1457@1,COG1457@2 NA|NA|NA F Belongs to the purine-cytosine permease (2.A.39) family MAG.T22.3_00006 1239962.C943_04067 1.3e-215 755.4 Cytophagia ko:K07133 ko00000 Bacteria 47U35@768503,4NE39@976,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) MAG.T22.3_00007 1239962.C943_04068 5.5e-189 666.8 Cytophagia frlR3 ko:K03710,ko:K07979 ko00000,ko03000 Bacteria 47YD4@768503,4PMHY@976,COG2188@1,COG2188@2 NA|NA|NA K helix_turn_helix gluconate operon transcriptional repressor MAG.T22.3_00009 1239962.C943_04070 0.0 1379.0 Cytophagia rhaD 1.1.1.1,4.1.2.19 ko:K00001,ko:K01629 ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R01785,R02124,R02263,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00438,RC00599,RC00603,RC00604,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 47JKR@768503,4NEM0@976,COG1028@1,COG1028@2,COG3347@1,COG3347@2 NA|NA|NA IQ TIGRFAM rhamnulose-1-phosphate aldolase alcohol dehydrogenase MAG.T22.3_00010 1239962.C943_04071 4.9e-235 820.1 Cytophagia rhaI 5.3.1.14 ko:K01820 ko00040,ko00051,ko01120,map00040,map00051,map01120 R01906,R02437,R06589 RC00376,RC00434,RC00516 ko00000,ko00001,ko01000 Bacteria 47KMM@768503,4NFWW@976,COG4952@1,COG4952@2 NA|NA|NA M TIGRFAM L-rhamnose catabolism isomerase, Pseudomonas stutzeri subtype MAG.T22.3_00011 1239962.C943_04072 2.5e-250 870.9 Cytophagia fucK 2.7.1.189 ko:K11216 ko02024,map02024 R11183 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 47MWB@768503,4NE3S@976,COG1070@1,COG1070@2 NA|NA|NA G Sugar (Pentulose and hexulose) MAG.T22.3_00012 641524.ADICYQ_5409 4.7e-91 341.3 Cytophagia Bacteria 2DU8V@1,33PDV@2,47TN9@768503,4P22M@976 NA|NA|NA S Domain of unknown function (DUF4221) MAG.T22.3_00014 866536.Belba_1140 1.7e-24 120.6 Cytophagia Bacteria 2DMS2@1,32TA5@2,47RPV@768503,4NUAP@976 NA|NA|NA S Domain of unknown function (DUF4221) MAG.T22.3_00016 1239962.C943_04074 2.7e-81 308.9 Bacteria Bacteria COG3391@1,COG3391@2 NA|NA|NA CO amine dehydrogenase activity MAG.T22.3_00018 1048983.EL17_00775 3.7e-117 428.3 Cytophagia Bacteria 2EYQX@1,33RYA@2,47U8W@768503,4P0VX@976 NA|NA|NA MAG.T22.3_00020 1123057.P872_00535 1.6e-38 166.4 Cytophagia lptC ko:K09774,ko:K11719 ko00000,ko02000 1.B.42.1 Bacteria 47R6J@768503,4NRIN@976,COG3117@1,COG3117@2 NA|NA|NA S Lipopolysaccharide-assembly, LptC-related MAG.T22.3_00021 1189612.A33Q_0326 6.5e-173 613.6 Bacteroidetes ko:K07133 ko00000 Bacteria 4NED3@976,COG1373@1,COG1373@2 NA|NA|NA S ATPase (AAA superfamily) MAG.T22.3_00022 649349.Lbys_0531 3e-29 136.0 Cytophagia 3.4.21.66 ko:K08651 ko00000,ko01000,ko01002,ko03110 Bacteria 47NC9@768503,4NF1M@976,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family MAG.T22.3_00023 1453498.LG45_13525 4.1e-69 268.9 Flavobacterium 3.4.21.66 ko:K08651 ko00000,ko01000,ko01002,ko03110 Bacteria 1I0IG@117743,2NX7A@237,4NF1M@976,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family MAG.T22.3_00025 1239962.C943_04080 2e-143 515.0 Cytophagia lldE ko:K18928 ko00000 Bacteria 47KGV@768503,4NIMP@976,COG0247@1,COG0247@2 NA|NA|NA C Fe-S oxidoreductase MAG.T22.3_00026 1239962.C943_04081 4.1e-264 916.8 Cytophagia lldF ko:K18929 ko00000 Bacteria 47K0Z@768503,4NEBT@976,COG1139@1,COG1139@2 NA|NA|NA C LUD domain MAG.T22.3_00027 1239962.C943_04082 7.6e-92 343.2 Cytophagia lldG ko:K00782 ko00000 Bacteria 47QGX@768503,4NQSF@976,COG1556@1,COG1556@2 NA|NA|NA S LUD domain MAG.T22.3_00028 1123057.P872_16840 2.3e-14 84.3 Cytophagia Bacteria 2DFCS@1,2ZRCA@2,47W9D@768503,4P8EP@976 NA|NA|NA MAG.T22.3_00029 1123057.P872_16835 3.7e-24 117.5 Cytophagia Bacteria 47S2D@768503,4NUUE@976,COG3668@1,COG3668@2 NA|NA|NA S ParE toxin of type II toxin-antitoxin system, parDE MAG.T22.3_00030 1239962.C943_04084 2.2e-249 867.8 Cytophagia ko:K03444 ko00000,ko02000 2.A.1.1 Bacteria 47MBV@768503,4NE09@976,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T22.3_00031 1123057.P872_21470 3.4e-89 334.3 Cytophagia pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 Bacteria 47MTK@768503,4NFI1@976,COG2065@1,COG2065@2 NA|NA|NA F Pyrimidine operon attenuation protein uracil phosphoribosyltransferase MAG.T22.3_00032 1239962.C943_04087 9.4e-164 582.8 Cytophagia pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15490 Bacteria 47KS2@768503,4NFIU@976,COG0540@1,COG0540@2 NA|NA|NA F Belongs to the ATCase OTCase family MAG.T22.3_00036 871963.Desdi_0303 1.5e-18 98.6 Clostridia ko:K07448 ko00000,ko02048 Bacteria 1UYEP@1239,24A6P@186801,COG1715@1,COG1715@2 NA|NA|NA L Restriction endonuclease MAG.T22.3_00037 867900.Celly_3186 1.6e-12 79.7 Flavobacteriia Bacteria 1I71V@117743,4NYCT@976,COG1848@1,COG1848@2 NA|NA|NA S Large family of predicted nucleotide-binding domains MAG.T22.3_00039 867900.Celly_3184 1.5e-43 183.3 Flavobacteriia ko:K03406,ko:K21470 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01002,ko01011,ko02035 Bacteria 1IKA7@117743,4NR2S@976,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase MAG.T22.3_00040 211165.AJLN01000074_gene6347 4e-83 315.5 Cyanobacteria ko:K06926 ko00000 Bacteria 1G3K0@1117,COG1106@1,COG1106@2 NA|NA|NA S AAA domain, putative AbiEii toxin, Type IV TA system MAG.T22.3_00042 1408813.AYMG01000016_gene4913 2.3e-222 778.5 Sphingobacteriia Bacteria 1IVZ3@117747,4NNC7@976,COG4249@1,COG4249@2 NA|NA|NA S Peptidase C14 caspase catalytic subunit p20 MAG.T22.3_00043 457424.BFAG_04539 3e-112 412.1 Bacteroidetes Bacteria 2DBDI@1,2Z8M4@2,4NJ8I@976 NA|NA|NA MAG.T22.3_00044 765420.OSCT_0924 3.5e-34 153.3 Bacteria 2.7.7.80 ko:K21029 ko04122,map04122 R07459 RC00043 ko00000,ko00001,ko01000 Bacteria COG0476@1,COG0476@2 NA|NA|NA H Involved in molybdopterin and thiamine biosynthesis, family 2 MAG.T22.3_00045 373994.Riv7116_4985 6.4e-17 94.0 Bacteria Bacteria COG1310@1,COG1310@2 NA|NA|NA S proteolysis MAG.T22.3_00046 1239962.C943_03861 3.6e-64 250.8 Cytophagia 3.1.21.4 ko:K01155 ko00000,ko01000,ko02048 Bacteria 47UUD@768503,4P2W3@976,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins MAG.T22.3_00047 1239962.C943_03863 0.0 1232.2 Cytophagia ko:K03671,ko:K03673 ko01503,ko04621,ko05418,map01503,map04621,map05418 M00728 ko00000,ko00001,ko00002,ko03110 Bacteria 47XHH@768503,4NTH5@976,COG0526@1,COG0526@2 NA|NA|NA CO AhpC/TSA family MAG.T22.3_00048 1239962.C943_03864 0.0 2102.4 Cytophagia Bacteria 47YNJ@768503,4NDXS@976,COG1629@1,COG1629@2 NA|NA|NA P Carboxypeptidase regulatory-like domain MAG.T22.3_00049 1239962.C943_03865 4e-251 873.6 Cytophagia Bacteria 47P49@768503,4NE18@976,COG1834@1,COG1834@2 NA|NA|NA E PFAM SusD family MAG.T22.3_00051 1239962.C943_03867 6.7e-62 243.4 Cytophagia Bacteria 28K7H@1,330T5@2,47RDT@768503,4NVUN@976 NA|NA|NA S Methylamine utilisation protein MauE MAG.T22.3_00052 1239962.C943_03869 2.4e-101 374.8 Bacteria Bacteria COG0664@1,COG0664@2 NA|NA|NA T cyclic nucleotide binding MAG.T22.3_00053 1239962.C943_03870 5.2e-114 417.5 Bacteria ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 Bacteria COG0664@1,COG0664@2 NA|NA|NA T cyclic nucleotide binding MAG.T22.3_00054 1120968.AUBX01000010_gene1418 1.5e-10 71.6 Cytophagia Bacteria 2DNTT@1,32Z3E@2,47T82@768503,4NVJI@976 NA|NA|NA MAG.T22.3_00055 1250005.PHEL85_1710 7.6e-54 217.2 Bacteroidetes Bacteria 4NQWX@976,COG1403@1,COG1403@2 NA|NA|NA V HNH nucleases MAG.T22.3_00056 1250005.PHEL85_1709 1.3e-67 264.2 Flavobacteriia Bacteria 1IKTX@117743,4NYNT@976,COG4637@1,COG4637@2 NA|NA|NA S AAA ATPase domain MAG.T22.3_00057 1304885.AUEY01000002_gene305 0.0 1159.8 Desulfobacterales hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1MU96@1224,2MHMG@213118,2WIT1@28221,42M86@68525,COG0610@1,COG0610@2 NA|NA|NA L Subunit R is required for both nuclease and ATPase activities, but not for modification MAG.T22.3_00058 323850.Shew_2274 3.3e-117 429.1 Bacteria Bacteria COG4637@1,COG4637@2 NA|NA|NA L Psort location Cytoplasmic, score MAG.T22.3_00059 401526.TcarDRAFT_1193 1.2e-68 267.3 Negativicutes hsdS 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1V66H@1239,4H537@909932,COG0732@1,COG0732@2 NA|NA|NA V specificity MAG.T22.3_00060 1304885.AUEY01000002_gene308 1.2e-183 649.8 Desulfobacterales hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1MW3A@1224,2MJCW@213118,2WINH@28221,42N9K@68525,COG0286@1,COG0286@2 NA|NA|NA V PFAM N-6 DNA methylase MAG.T22.3_00061 926562.Oweho_0037 7.6e-07 61.2 Flavobacteriia Bacteria 1I8UD@117743,29CR1@1,2ZZP8@2,4PFV0@976 NA|NA|NA S Protein of unknown function (DUF2490) MAG.T22.3_00062 1239962.C943_03741 1.2e-95 355.9 Bacteroidetes Bacteria 2BVY1@1,32QYH@2,4NR2M@976 NA|NA|NA MAG.T22.3_00063 1267211.KI669560_gene2598 4.7e-31 140.2 Bacteroidetes 5.3.3.4 ko:K03464 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R06990 RC01109 ko00000,ko00001,ko00002,ko01000 Bacteria 2EGEP@1,33A6N@2,4NXT1@976 NA|NA|NA MAG.T22.3_00064 1239962.C943_03738 1.4e-75 288.9 Bacteroidetes Bacteria 29A0I@1,2ZX23@2,4NYBQ@976 NA|NA|NA S Uncharacterized protein family, UPF0114 MAG.T22.3_00065 1239962.C943_03737 0.0 1134.0 Cytophagia atsA 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 47J95@768503,4NEBN@976,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase MAG.T22.3_00066 1239962.C943_03736 7e-101 373.2 Cytophagia Bacteria 2C852@1,32YB2@2,47SHZ@768503,4NM63@976 NA|NA|NA S Domain of unknown function (DUF4136) MAG.T22.3_00068 1239962.C943_03733 2.5e-294 1017.3 Bacteroidetes 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 4P3P6@976,COG0457@1,COG0457@2,COG5616@1,COG5616@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.3_00069 860228.Ccan_23760 1.6e-148 532.3 Capnocytophaga Bacteria 1ETEC@1016,1HZ5U@117743,4NGY8@976,COG4804@1,COG4804@2 NA|NA|NA S Psort location Cytoplasmic, score 8.96 MAG.T22.3_00070 1239415.CM001837_gene1795 1.7e-29 135.6 Dokdonia Bacteria 1I4RZ@117743,2D02M@1,32T7M@2,37FI6@326319,4NT0X@976 NA|NA|NA MAG.T22.3_00071 1229487.AMYW01000016_gene2479 7.5e-39 167.5 Bacteria Bacteria 2CI9M@1,335Q7@2 NA|NA|NA MAG.T22.3_00073 1121098.HMPREF1534_02085 8.3e-23 112.8 Bacteroidaceae ko:K19158 ko00000,ko01000,ko02048 Bacteria 2FUIS@200643,4ASEK@815,4NUMR@976,COG4115@1,COG4115@2 NA|NA|NA S YoeB-like toxin of bacterial type II toxin-antitoxin system MAG.T22.3_00076 1239962.C943_03732 2.1e-79 301.6 Cytophagia XK27_03185 ko:K16785 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 47PPX@768503,4NNW2@976,COG4696@1,COG4696@2 NA|NA|NA S PFAM Phosphoribosyl-ATP pyrophosphohydrolase MAG.T22.3_00077 1239962.C943_03730 8.1e-140 503.1 Cytophagia sodA 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Bacteria 47N71@768503,4NK61@976,COG0605@1,COG0605@2 NA|NA|NA P Destroys radicals which are normally produced within the cells and which are toxic to biological systems MAG.T22.3_00078 1239962.C943_03729 9.4e-141 506.1 Cytophagia dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 iIT341.HP0566,iLJ478.TM1522 Bacteria 47KR3@768503,4NF26@976,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan MAG.T22.3_00079 1239962.C943_03728 0.0 2178.7 Cytophagia secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 47JTE@768503,4NF7C@976,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane MAG.T22.3_00080 1239962.C943_03727 3.6e-94 350.9 Cytophagia Bacteria 2EJD3@1,33D44@2,47PW7@768503,4NP3M@976 NA|NA|NA MAG.T22.3_00081 1239962.C943_03726 4.2e-220 770.4 Cytophagia ammA ko:K01436 ko00000,ko01000,ko01002 Bacteria 47KGA@768503,4NGBI@976,COG1473@1,COG1473@2 NA|NA|NA S PFAM Peptidase family M20 M25 M40 MAG.T22.3_00082 1239962.C943_03725 5.7e-146 523.5 Cytophagia Bacteria 28JIP@1,2Z82C@2,47PJT@768503,4NFN9@976 NA|NA|NA S S1 P1 nuclease MAG.T22.3_00083 1239962.C943_03724 2.1e-141 508.4 Cytophagia hisK 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 47Q20@768503,4NIJU@976,COG1387@1,COG1387@2 NA|NA|NA E PHP domain MAG.T22.3_00084 1239962.C943_03723 1.4e-134 485.7 Cytophagia mscS ko:K03442 ko00000,ko02000 1.A.23.2 Bacteria 47MG7@768503,4NEPW@976,COG0668@1,COG0668@2 NA|NA|NA M PFAM Mechanosensitive ion channel MAG.T22.3_00085 1239962.C943_03722 2e-71 275.0 Bacteroidetes Bacteria 2EHKQ@1,33BCG@2,4NZQK@976 NA|NA|NA MAG.T22.3_00086 1239962.C943_03721 0.0 1154.4 Cytophagia Bacteria 47NUP@768503,4NFUI@976,COG1680@1,COG1680@2 NA|NA|NA V Domain of unknown function (DUF3471) MAG.T22.3_00087 1239962.C943_03720 0.0 1335.5 Cytophagia recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 47JUE@768503,4NDZV@976,COG1200@1,COG1200@2 NA|NA|NA L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) MAG.T22.3_00088 1239962.C943_03719 3e-140 504.6 Cytophagia mscS ko:K03442 ko00000,ko02000 1.A.23.2 Bacteria 47MG7@768503,4NEPW@976,COG0668@1,COG0668@2 NA|NA|NA M PFAM Mechanosensitive ion channel MAG.T22.3_00089 1239962.C943_03718 5.2e-114 417.2 Cytophagia Bacteria 47PMX@768503,4NM9E@976,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase MAG.T22.3_00090 1239962.C943_03717 7.3e-192 676.4 Cytophagia bcsA Bacteria 47JU1@768503,4NDZU@976,COG3424@1,COG3424@2 NA|NA|NA Q PFAM chalcone and stilbene MAG.T22.3_00091 1239962.C943_03716 1.2e-163 582.4 Cytophagia 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 47N2W@768503,4NK26@976,COG0382@1,COG0382@2 NA|NA|NA H UbiA prenyltransferase family MAG.T22.3_00092 886379.AEWI01000010_gene609 3.5e-20 104.4 Marinilabiliaceae Bacteria 2G22Q@200643,3XM02@558415,4PIZT@976,COG1708@1,COG1708@2 NA|NA|NA S Nucleotidyltransferase domain MAG.T22.3_00093 471854.Dfer_2737 2e-41 175.3 Cytophagia Bacteria 47VY5@768503,4NYJS@976,COG2250@1,COG2250@2 NA|NA|NA S HEPN domain MAG.T22.3_00094 1239962.C943_03715 3.3e-195 687.6 Cytophagia fixC 1.3.99.38 ko:K21401 ko00000,ko01000 Bacteria 47M1U@768503,4NE67@976,COG0644@1,COG0644@2 NA|NA|NA C FAD binding domain MAG.T22.3_00095 1239962.C943_03714 0.0 1624.8 Cytophagia Bacteria 47JCM@768503,4NEA0@976,COG5549@1,COG5549@2 NA|NA|NA O Domain of unknown function (DUF5118) MAG.T22.3_00096 1123057.P872_01960 1.6e-51 208.8 Cytophagia fur ko:K03711,ko:K09825 ko00000,ko03000 Bacteria 47PU3@768503,4NSES@976,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family MAG.T22.3_00097 1239962.C943_03711 2.9e-29 134.0 Cytophagia Bacteria 2DX4P@1,343CF@2,47VVY@768503,4P648@976 NA|NA|NA MAG.T22.3_00098 1239962.C943_03710 7.1e-83 313.2 Cytophagia Bacteria 2C88U@1,2ZAHP@2,47NBI@768503,4NK63@976 NA|NA|NA MAG.T22.3_00099 1239962.C943_03709 1.3e-79 302.4 Cytophagia Bacteria 47QEC@768503,4NMAH@976,COG2335@1,COG2335@2 NA|NA|NA M Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. MAG.T22.3_00100 1239962.C943_03708 1.2e-77 295.8 Cytophagia rlmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 ko:K00783 ko00000,ko01000,ko03009 Bacteria 47Q9Z@768503,4NMFP@976,COG1576@1,COG1576@2 NA|NA|NA J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA MAG.T22.3_00101 1239962.C943_03705 3.3e-261 907.1 Bacteroidetes Bacteria 4NKSK@976,COG5361@1,COG5361@2 NA|NA|NA S Protein of unknown function (DUF1214) MAG.T22.3_00102 1239962.C943_03702 0.0 1228.0 Cytophagia Bacteria 47XA2@768503,4NNVK@976,COG3291@1,COG3291@2 NA|NA|NA S PKD domain MAG.T22.3_00103 1239962.C943_03701 3.6e-301 1040.0 Cytophagia phrB GO:0000166,GO:0000719,GO:0003674,GO:0003824,GO:0003913,GO:0003914,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363 ko:K06876 ko00000 Bacteria 47N6N@768503,4NECD@976,COG3046@1,COG3046@2 NA|NA|NA S Deoxyribodipyrimidine photo-lyase-related protein MAG.T22.3_00104 1239962.C943_03700 1.3e-202 712.2 Cytophagia dmpA 3.4.11.19 ko:K01266 ko00000,ko01000,ko01002 Bacteria 47K9S@768503,4NGDT@976,COG3191@1,COG3191@2 NA|NA|NA EQ Peptidase family S58 MAG.T22.3_00105 1239962.C943_03699 1.2e-258 898.7 Cytophagia alkH 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 47KZA@768503,4NGHD@976,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family MAG.T22.3_00108 1239962.C943_03696 0.0 2828.1 Bacteroidetes Bacteria 4NMB8@976,COG1361@1,COG1361@2 NA|NA|NA M Conserved repeat domain MAG.T22.3_00109 1239962.C943_03695 8.9e-181 639.4 Cytophagia Bacteria 47KE6@768503,4NEVD@976,COG3064@1,COG3064@2 NA|NA|NA M TIGRFAM Bacteroidetes-specific MAG.T22.3_00110 1239962.C943_03694 0.0 1446.4 Cytophagia Bacteria 47UJH@768503,4NE6G@976,COG2885@1,COG2885@2 NA|NA|NA M Belongs to the ompA family MAG.T22.3_00111 1239962.C943_03692 4.1e-234 817.0 Cytophagia yebA Bacteria 47MV0@768503,4NECF@976,COG0739@1,COG0739@2 NA|NA|NA M PFAM Peptidase family M23 MAG.T22.3_00112 1239962.C943_03690 0.0 1155.6 Cytophagia aspS GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iJN678.aspS,iSFV_1184.SFV_1868 Bacteria 47JC8@768503,4NECY@976,COG0173@1,COG0173@2 NA|NA|NA J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) MAG.T22.3_00113 1239962.C943_03689 0.0 1809.3 Cytophagia Bacteria 47JEF@768503,4NF88@976,COG1629@1,COG1629@2 NA|NA|NA P Outer membrane protein beta-barrel family MAG.T22.3_00114 1189612.A33Q_2418 7.2e-82 310.1 Cytophagia Bacteria 47PET@768503,4NMAH@976,COG2335@1,COG2335@2 NA|NA|NA M Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. MAG.T22.3_00115 1239962.C943_03683 2.1e-94 351.7 Bacteria 3.1.1.32,3.1.1.4 ko:K01058,ko:K07502 ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110 R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko01000 Bacteria COG0790@1,COG0790@2 NA|NA|NA S beta-lactamase activity MAG.T22.3_00116 637911.AM305_10975 3.1e-21 109.4 Pasteurellales Bacteria 1PY8F@1224,1TA9B@1236,1YA5T@135625,COG1502@1,COG1502@2 NA|NA|NA I Protein of unknown function (DUF1669) MAG.T22.3_00117 1239962.C943_03682 2.8e-232 810.8 Cytophagia lysA 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 47JBT@768503,4NE7X@976,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine MAG.T22.3_00118 1239962.C943_03681 0.0 1086.2 Cytophagia rprX 2.7.13.3 ko:K02484,ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 47MII@768503,4PKBV@976,COG5002@1,COG5002@2 NA|NA|NA T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MAG.T22.3_00119 1239962.C943_03680 2e-126 458.4 Cytophagia Bacteria 47KCE@768503,4NF1I@976,COG0745@1,COG0745@2 NA|NA|NA T PFAM response regulator receiver MAG.T22.3_00120 1239962.C943_03679 1e-213 749.2 Cytophagia Bacteria 47JYZ@768503,4NI5M@976,COG4409@1,COG4409@2 NA|NA|NA G exo-alpha-(2->6)-sialidase activity MAG.T22.3_00124 1239962.C943_03675 8.1e-282 975.7 Cytophagia Bacteria 47TZX@768503,4NF48@976,COG2939@1,COG2939@2 NA|NA|NA E Serine carboxypeptidase MAG.T22.3_00125 1239962.C943_03673 1e-252 879.0 Cytophagia rutC 4.2.99.21 ko:K04782 ko01053,ko01110,ko01130,map01053,map01110,map01130 R06602 RC01549,RC02148 ko00000,ko00001,ko01000 Bacteria 47XV2@768503,4P1NX@976,COG0251@1,COG0251@2,COG0667@1,COG0667@2 NA|NA|NA CJ Endoribonuclease L-PSP MAG.T22.3_00126 1239962.C943_03672 1e-244 852.4 Bacteria steT ko:K03294 ko00000 2.A.3.2 Bacteria COG0531@1,COG0531@2 NA|NA|NA E amino acid MAG.T22.3_00128 1239962.C943_03670 0.0 1832.8 Cytophagia 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 47JVA@768503,4NG6P@976,COG0553@1,COG0553@2 NA|NA|NA L PFAM Helicase conserved C-terminal domain MAG.T22.3_00129 1239962.C943_03669 1e-159 569.3 Cytophagia purU GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006753,GO:0006760,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008864,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009256,GO:0009257,GO:0009259,GO:0009260,GO:0009396,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0034641,GO:0034654,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.72,3.5.1.10 ko:K00974,ko:K01433 ko00630,ko00670,ko03013,map00630,map00670,map03013 R00944,R09382,R09383,R09384,R09386 RC00026,RC00078,RC00111 ko00000,ko00001,ko01000,ko03016 iSDY_1059.SDY_1284 Bacteria 47N6W@768503,4NEGJ@976,COG0788@1,COG0788@2 NA|NA|NA F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) MAG.T22.3_00130 83406.HDN1F_36300 4.5e-22 110.2 unclassified Gammaproteobacteria ko:K07746 ko00000,ko02048 Bacteria 1JBCT@118884,1N9NJ@1224,1S9Z4@1236,COG3609@1,COG3609@2 NA|NA|NA K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain MAG.T22.3_00132 485917.Phep_3599 2.1e-149 535.4 Sphingobacteriia Bacteria 1IW3F@117747,4NFBY@976,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family N-terminal MAG.T22.3_00133 1239962.C943_03667 1.2e-180 639.0 Cytophagia arsB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 ko:K03325 ko00000,ko02000 2.A.59 Bacteria 47M0B@768503,4NFG7@976,COG0798@1,COG0798@2 NA|NA|NA P PFAM Sodium Bile acid symporter family MAG.T22.3_00134 1239962.C943_03666 1.3e-105 389.0 Cytophagia arsC 1.20.4.1 ko:K03741 ko00000,ko01000 Bacteria 47PXK@768503,4NE8C@976,COG0394@1,COG0394@2 NA|NA|NA T PFAM Low molecular weight phosphotyrosine protein phosphatase MAG.T22.3_00135 1239962.C943_03665 2.4e-95 354.8 Cytophagia Bacteria 2DBYA@1,2ZBU9@2,47PHW@768503,4NPNW@976 NA|NA|NA MAG.T22.3_00136 1239962.C943_03664 3.3e-55 220.7 Cytophagia Bacteria 47R2A@768503,4NQK3@976,COG0640@1,COG0640@2 NA|NA|NA K PFAM Bacterial regulatory protein, arsR family MAG.T22.3_00137 1239962.C943_03663 1.5e-71 275.4 Cytophagia Bacteria 47RJ8@768503,4NNJ3@976,COG2318@1,COG2318@2 NA|NA|NA S DinB family MAG.T22.3_00138 1239962.C943_03658 0.0 1358.6 Cytophagia Bacteria 47KG6@768503,4NE96@976,COG1434@1,COG1434@2 NA|NA|NA S Gram-negative-bacterium-type cell wall biogenesis MAG.T22.3_00139 1239962.C943_03657 5.1e-148 530.4 Cytophagia 2.7.4.1 ko:K22468 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 47MY7@768503,4NFJ5@976,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate kinase 2 (PPK2) MAG.T22.3_00140 1239962.C943_03656 3e-134 484.6 Cytophagia 2.7.4.1 ko:K22468 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 47MY7@768503,4NFJ5@976,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate kinase 2 (PPK2) MAG.T22.3_00141 1239962.C943_03655 3.7e-266 923.7 Cytophagia 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 47T9Y@768503,4NGQX@976,COG0469@1,COG0469@2 NA|NA|NA G Pyruvate kinase, barrel domain MAG.T22.3_00142 1239962.C943_03654 1e-276 958.7 Cytophagia Bacteria 47NVH@768503,4NF9K@976,COG1409@1,COG1409@2 NA|NA|NA S N terminal of Calcineurin-like phosphoesterase MAG.T22.3_00143 1239962.C943_03648 4.8e-88 330.5 Cytophagia Bacteria 47SXX@768503,4NP71@976,COG2930@1,COG2930@2 NA|NA|NA S Las17-binding protein actin regulator MAG.T22.3_00144 1239962.C943_03647 5.4e-217 760.0 Cytophagia Bacteria 47VW0@768503,4NGFN@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 MAG.T22.3_00145 1239962.C943_03646 6.1e-205 719.9 Cytophagia wcoF Bacteria 47XD6@768503,4NKNB@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 MAG.T22.3_00146 1239962.C943_03645 3.4e-129 467.6 Cytophagia 2.3.1.79 ko:K00661 ko00000,ko01000 Bacteria 47PJX@768503,4NRD8@976,COG0110@1,COG0110@2 NA|NA|NA S Acetyltransferase (Isoleucine patch superfamily) MAG.T22.3_00147 1239962.C943_03644 4e-209 733.8 Cytophagia Bacteria 47KRN@768503,4NETA@976,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferases group 1 MAG.T22.3_00148 1239962.C943_03643 1e-230 805.8 Cytophagia Bacteria 28MQY@1,2ZAZN@2,47TUF@768503,4NNM1@976 NA|NA|NA MAG.T22.3_00150 880071.Fleli_3233 5.6e-32 144.1 Bacteroidetes Bacteria 2E8EC@1,332SS@2,4NX79@976 NA|NA|NA MAG.T22.3_00153 1239962.C943_03639 9.1e-176 622.9 Cytophagia pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 47JM1@768503,4NF8I@976,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily MAG.T22.3_00155 1239962.C943_03636 6.9e-136 490.0 Cytophagia pcrB GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 ko:K07094 ko00000,ko01000 Bacteria 47MXM@768503,4NER8@976,COG1646@1,COG1646@2 NA|NA|NA I Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P) MAG.T22.3_00156 1189612.A33Q_2421 7.3e-22 110.2 Cytophagia Bacteria 2FG2X@1,347ZK@2,47W7P@768503,4P6M8@976 NA|NA|NA MAG.T22.3_00157 866536.Belba_1056 2.1e-15 88.6 Cytophagia Bacteria 2DY43@1,3481M@2,47VUB@768503,4P57W@976 NA|NA|NA S Putative Actinobacterial Holin-X, holin superfamily III MAG.T22.3_00158 1239962.C943_03633 1.3e-106 392.5 Cytophagia Bacteria 47PTF@768503,4NMJ0@976,COG0727@1,COG0727@2 NA|NA|NA S Putative zinc- or iron-chelating domain MAG.T22.3_00159 1239962.C943_03632 2.7e-158 564.7 Cytophagia mltD_2 Bacteria 47MPP@768503,4NH4W@976,COG0741@1,COG0741@2 NA|NA|NA M Transglycosylase SLT domain MAG.T22.3_00160 1239962.C943_03631 0.0 1106.3 Cytophagia Bacteria 2C5U1@1,2Z80K@2,47RZF@768503,4NG4G@976 NA|NA|NA MAG.T22.3_00161 1239962.C943_03630 0.0 1857.8 Cytophagia uvrA ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 47K0C@768503,4NFQU@976,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate MAG.T22.3_00162 1239962.C943_03629 1.9e-181 641.7 Cytophagia Bacteria 47K66@768503,4NI09@976,COG2972@1,COG2972@2 NA|NA|NA T Histidine kinase MAG.T22.3_00163 1239962.C943_03628 5.2e-133 480.3 Cytophagia ko:K02477 ko00000,ko02022 Bacteria 47N62@768503,4NFWA@976,COG3279@1,COG3279@2 NA|NA|NA T Response regulator of the LytR AlgR family MAG.T22.3_00164 1239962.C943_03627 1.7e-134 485.3 Cytophagia ko:K07705 ko02020,map02020 M00492 ko00000,ko00001,ko00002,ko02022 Bacteria 47KZY@768503,4NF8A@976,COG3279@1,COG3279@2 NA|NA|NA K Response regulator of the LytR AlgR family MAG.T22.3_00165 1189612.A33Q_2431 3.9e-25 120.9 Cytophagia Bacteria 2DPHJ@1,3323Y@2,47SBG@768503,4NWI8@976 NA|NA|NA MAG.T22.3_00166 1239962.C943_03624 8.4e-254 882.5 Cytophagia phoH ko:K07175 ko00000 Bacteria 47M94@768503,4NDUI@976,COG1875@1,COG1875@2 NA|NA|NA T PIN domain MAG.T22.3_00167 1239962.C943_03622 3.7e-120 437.6 Cytophagia Z012_09595 1.6.5.2 ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 Bacteria 47PKG@768503,4NM3V@976,COG2249@1,COG2249@2 NA|NA|NA H NADPH-dependent FMN reductase MAG.T22.3_00168 1239962.C943_03621 3.5e-106 391.0 Cytophagia ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 47R15@768503,4PMKG@976,COG3258@1,COG3258@2 NA|NA|NA C Protein of unknown function (DUF3365) MAG.T22.3_00169 1239962.C943_03620 2.1e-251 875.5 Bacteroidetes Bacteria 4NRP7@976,COG4447@1,COG4447@2 NA|NA|NA UW protein related to plant photosystem II stability assembly factor MAG.T22.3_00170 1239962.C943_03619 3.2e-239 833.9 Cytophagia mdeA 2.5.1.48,4.4.1.11,4.4.1.8 ko:K01739,ko:K01760,ko:K01761 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 Bacteria 47P29@768503,4NIV1@976,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme MAG.T22.3_00173 1286632.P278_28230 6.1e-107 394.0 Flavobacteriia Bacteria 1I8ZF@117743,2DNBW@1,32UIP@2,4P3DX@976 NA|NA|NA S PD-(D/E)XK nuclease superfamily MAG.T22.3_00175 1123057.P872_06040 3e-51 209.5 Cytophagia Bacteria 29TTU@1,30F26@2,47RK6@768503,4NPF7@976 NA|NA|NA S PD-(D/E)XK nuclease superfamily MAG.T22.3_00177 1288963.ADIS_0878 2.1e-232 813.1 Bacteroidetes recQ 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 4NIG1@976,COG0514@1,COG0514@2 NA|NA|NA L helicase superfamily c-terminal domain MAG.T22.3_00178 391587.KAOT1_02044 6.6e-50 205.7 Flavobacteriia Bacteria 1I1IA@117743,4NN8D@976,COG0846@1,COG0846@2 NA|NA|NA K SIR2-like domain MAG.T22.3_00180 1239962.C943_04492 3.2e-109 401.0 Cytophagia hisB GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034200,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.6.1.9,3.1.3.15,3.1.3.82,3.1.3.83,4.2.1.19 ko:K00013,ko:K00817,ko:K01089,ko:K01693,ko:K03273 ko00340,ko00350,ko00360,ko00400,ko00401,ko00540,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00540,map00960,map01100,map01110,map01130,map01230 M00026,M00064 R00694,R00734,R01158,R01163,R03012,R03013,R03243,R03457,R05647,R09771 RC00006,RC00017,RC00099,RC00242,RC00463,RC00888,RC00932 ko00000,ko00001,ko00002,ko01000,ko01005,ko01007 iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iLJ478.TM1039,iSB619.SA_RS14130,iUMNK88_1353.UMNK88_2570 Bacteria 47J9I@768503,4NENP@976,COG0131@1,COG0131@2,COG0241@1,COG0241@2 NA|NA|NA E belongs to the imidazoleglycerol-phosphate dehydratase family MAG.T22.3_00181 1189612.A33Q_0997 5.2e-72 277.3 Cytophagia Bacteria 2C984@1,32U95@2,47TTJ@768503,4NSEJ@976 NA|NA|NA MAG.T22.3_00182 1123057.P872_10885 9.6e-23 113.2 Cytophagia Bacteria 2EK9Y@1,33E08@2,47V48@768503,4NXVI@976 NA|NA|NA MAG.T22.3_00183 1288963.ADIS_4712 1.2e-31 143.7 Cytophagia Bacteria 47SPW@768503,4NYBD@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.3_00184 1239962.C943_04489 4.4e-303 1046.6 Cytophagia sppA GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 ko:K04773 ko00000,ko01000,ko01002 Bacteria 47KQH@768503,4NES1@976,COG0616@1,COG0616@2 NA|NA|NA OU signal peptide peptidase SppA, 36K type MAG.T22.3_00185 1239962.C943_04488 2.3e-68 265.0 Cytophagia folK 2.7.6.3,4.1.2.25 ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503,R03504 RC00002,RC00017,RC00721,RC00943 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0041 Bacteria 47QG8@768503,4NGE8@976,COG0801@1,COG0801@2 NA|NA|NA H TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase MAG.T22.3_00186 1239962.C943_04487 6.6e-159 566.6 Cytophagia fabD 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 47JDE@768503,4NE1D@976,COG0331@1,COG0331@2 NA|NA|NA I malonyl CoA-acyl carrier protein transacylase MAG.T22.3_00187 1239962.C943_04486 0.0 1369.4 Cytophagia 3.5.1.97 ko:K07116 ko00000,ko01000 Bacteria 47JE7@768503,4NGXQ@976,COG2366@1,COG2366@2 NA|NA|NA S Penicillin amidase MAG.T22.3_00188 1239962.C943_04485 1.3e-88 332.4 Bacteria Bacteria 2DEMQ@1,2ZNHH@2 NA|NA|NA S Protein of unknown function (DUF2384) MAG.T22.3_00189 1239962.C943_04484 8.6e-73 279.6 Bacteria Bacteria COG5654@1,COG5654@2 NA|NA|NA S RES MAG.T22.3_00190 1239962.C943_04483 2e-104 385.2 Cytophagia Bacteria 47NRD@768503,4NH3F@976,COG1280@1,COG1280@2 NA|NA|NA E PFAM Lysine exporter protein (LYSE YGGA) MAG.T22.3_00191 1239962.C943_04482 3.3e-286 990.3 Cytophagia Bacteria 47K42@768503,4PKQG@976,COG0318@1,COG0318@2 NA|NA|NA IQ GH3 auxin-responsive promoter MAG.T22.3_00192 1239962.C943_04481 2.9e-109 401.4 Cytophagia yggS ko:K06997 ko00000 Bacteria 47M4Y@768503,4NE42@976,COG0325@1,COG0325@2 NA|NA|NA S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis MAG.T22.3_00193 1239962.C943_04480 2.9e-58 231.1 Cytophagia ygdD Bacteria 47RJW@768503,4NS8F@976,COG2363@1,COG2363@2 NA|NA|NA S small membrane protein MAG.T22.3_00194 1239962.C943_04479 3.6e-241 840.5 Cytophagia dacB GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006508,GO:0006807,GO:0007049,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009987,GO:0016043,GO:0016787,GO:0016998,GO:0017171,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0030203,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0032505,GO:0033218,GO:0033293,GO:0036094,GO:0042597,GO:0043093,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044464,GO:0045229,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0097159,GO:0140096,GO:1901135,GO:1901136,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901681 3.4.16.4 ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 iAPECO1_1312.APECO1_3250,iECOK1_1307.ECOK1_3603,iECS88_1305.ECS88_3564,iUMN146_1321.UM146_00470,iUTI89_1310.UTI89_C3615,iYL1228.KPN_03592 Bacteria 47JKB@768503,4NGIQ@976,COG2027@1,COG2027@2 NA|NA|NA M PFAM D-Ala-D-Ala carboxypeptidase 3 (S13) family MAG.T22.3_00196 1239962.C943_04478 3.3e-189 667.5 Cytophagia ldcA 3.4.17.13 ko:K01297 ko00000,ko01000,ko01002,ko01011 Bacteria 47KS4@768503,4NF5Q@976,COG1619@1,COG1619@2 NA|NA|NA V peptidase U61 LD-carboxypeptidase A MAG.T22.3_00197 1239962.C943_04477 4.9e-120 437.2 Cytophagia Bacteria 47PEW@768503,4NNIC@976,COG2755@1,COG2755@2 NA|NA|NA E PFAM GDSL-like Lipase Acylhydrolase MAG.T22.3_00198 1239962.C943_04476 2.9e-125 454.5 Cytophagia ko:K03668 ko00000 Bacteria 47SY5@768503,4PKCG@976,COG3187@1,COG3187@2 NA|NA|NA O Domain of unknown function (DUF4377) MAG.T22.3_00199 746697.Aeqsu_2767 1.9e-12 79.7 Flavobacteriia ko:K03668 ko00000 Bacteria 1I2I7@117743,4NNI9@976,COG3187@1,COG3187@2 NA|NA|NA O META domain MAG.T22.3_00200 1239962.C943_04475 1.7e-243 848.2 Cytophagia Bacteria 28HE2@1,2Z7QJ@2,47UN2@768503,4NFBA@976 NA|NA|NA S Domain of unknown function (DUF5103) MAG.T22.3_00201 1239962.C943_04470 2.2e-298 1030.8 Cytophagia PGCP Bacteria 47M14@768503,4NE66@976,COG2234@1,COG2234@2 NA|NA|NA G Peptidase, M28 MAG.T22.3_00202 1239962.C943_04469 1.6e-177 628.6 Cytophagia mtnK GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.100 ko:K00899 ko00270,ko01100,map00270,map01100 M00034 R04143 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 47JME@768503,4NHKI@976,COG4857@1,COG4857@2 NA|NA|NA S Phosphotransferase enzyme family MAG.T22.3_00203 1239962.C943_04467 1.3e-211 742.3 Cytophagia Bacteria 47U70@768503,4NISQ@976,COG1397@1,COG1397@2 NA|NA|NA O ADP-ribosylglycohydrolase MAG.T22.3_00204 1239962.C943_04466 1.1e-28 132.1 Bacteria Bacteria 2EFFN@1,3398D@2 NA|NA|NA MAG.T22.3_00205 1239962.C943_04465 5.7e-90 337.0 Cytophagia Bacteria 2EJ5R@1,33CWY@2,47SY4@768503,4NYJK@976 NA|NA|NA MAG.T22.3_00206 1239962.C943_04464 5.7e-94 350.1 Cytophagia ysmA ko:K07107,ko:K12500 ko00000,ko01000,ko01004 Bacteria 47N55@768503,4NK6Y@976,COG0824@1,COG0824@2 NA|NA|NA S Thioesterase-like superfamily MAG.T22.3_00207 1239962.C943_04463 3e-136 491.1 Cytophagia ybgL ko:K07160 ko00000 Bacteria 47JP6@768503,4NJ86@976,COG1540@1,COG1540@2 NA|NA|NA S Belongs to the UPF0271 (lamB) family MAG.T22.3_00208 1239962.C943_04462 1.8e-103 382.1 Cytophagia ybgJ 3.5.1.54 ko:K01457,ko:K06351,ko:K07160 ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120 R00005 RC02756 ko00000,ko00001,ko01000 Bacteria 47QUS@768503,4NMNT@976,COG2049@1,COG2049@2 NA|NA|NA E PFAM Allophanate hydrolase subunit 1 MAG.T22.3_00209 1239962.C943_04461 1.1e-158 565.8 Cytophagia kipA 6.3.4.6 ko:K01941,ko:K06350 ko00220,ko00791,ko01100,map00220,map00791,map01100 R00774 RC00378 ko00000,ko00001,ko01000 Bacteria 47RJD@768503,4NGIV@976,COG1984@1,COG1984@2 NA|NA|NA E PFAM Allophanate hydrolase subunit 2 MAG.T22.3_00210 1239962.C943_04460 9.7e-267 925.6 Cytophagia Bacteria 47KCU@768503,4NEQF@976,COG3172@1,COG3172@2 NA|NA|NA H Domain of unknown function (DUF4301) MAG.T22.3_00211 1239962.C943_04458 2.5e-47 194.5 Bacteria 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria COG1708@1,COG1708@2 NA|NA|NA S nucleotidyltransferase activity MAG.T22.3_00212 1239962.C943_04457 2.1e-67 261.5 Cytophagia Bacteria 47S9Z@768503,4NS8N@976,COG1669@1,COG1669@2 NA|NA|NA S Nucleotidyltransferase substrate binding protein like MAG.T22.3_00213 1239962.C943_04456 2.1e-163 581.6 Cytophagia Bacteria 47QC2@768503,4NN6R@976,COG2378@1,COG2378@2 NA|NA|NA K WYL domain MAG.T22.3_00214 1239962.C943_04455 1.2e-157 562.4 Cytophagia pagC ko:K07804 ko02020,map02020 ko00000,ko00001 Bacteria 47NZ9@768503,4NE33@976,COG3637@1,COG3637@2 NA|NA|NA M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety MAG.T22.3_00215 1239962.C943_04454 3.7e-67 261.2 Bacteria Bacteria COG2353@1,COG2353@2 NA|NA|NA O YceI-like domain MAG.T22.3_00216 1239962.C943_04452 2.7e-85 321.2 Cytophagia petC 1.10.9.1 ko:K02636 ko00195,ko01100,map00195,map01100 M00162 R03817,R08409 RC01002 ko00000,ko00001,ko00002,ko00194,ko01000 Bacteria 47XU4@768503,4NZM1@976,COG0723@1,COG0723@2 NA|NA|NA C Rieske [2Fe-2S] domain MAG.T22.3_00217 1189612.A33Q_1032 1.5e-25 122.9 Cytophagia Bacteria 2DRZJ@1,33DU7@2,47SXI@768503,4NXZF@976 NA|NA|NA MAG.T22.3_00218 1239962.C943_04450 0.0 2004.2 Cytophagia smc GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03529,ko:K19171 ko00000,ko02048,ko03036 Bacteria 47JHP@768503,4NHWQ@976,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning MAG.T22.3_00219 1239962.C943_04449 2.7e-255 887.5 Cytophagia Bacteria 47RPZ@768503,4NH2A@976,COG0526@1,COG0526@2 NA|NA|NA O Thiol-disulfide isomerase-like thioredoxin MAG.T22.3_00220 1121904.ARBP01000005_gene4823 2.5e-93 349.0 Cytophagia Bacteria 28MAS@1,2ZAPE@2,47TP8@768503,4NJ31@976 NA|NA|NA S Protein of unknown function, DUF481 MAG.T22.3_00221 1239962.C943_04448 5.8e-291 1006.1 Cytophagia Bacteria 47MU2@768503,4NFFC@976,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) MAG.T22.3_00222 1239962.C943_04447 0.0 1134.4 Cytophagia Bacteria 47MD4@768503,4NHSB@976,COG5267@1,COG5267@2 NA|NA|NA S Protein of unknown function (DUF1800) MAG.T22.3_00223 1239962.C943_04446 2.3e-223 781.2 Cytophagia yieL ko:K07214 ko00000 Bacteria 47PFY@768503,4NFVV@976,COG2382@1,COG2382@2 NA|NA|NA P Belongs to the glycosyl hydrolase 13 family MAG.T22.3_00224 1239962.C943_04445 2e-247 861.3 Cytophagia 5.1.3.11 ko:K16213 R01445,R10810 RC00289 ko00000,ko01000 Bacteria 47XH4@768503,4NEH7@976,COG2942@1,COG2942@2 NA|NA|NA G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) MAG.T22.3_00225 1305737.JAFX01000001_gene2637 3.8e-151 542.0 Cytophagia ko:K02014 ko00000,ko02000 1.B.14 Bacteria 47Y3N@768503,4PM72@976,COG1629@1,COG1629@2 NA|NA|NA P Domain of unknown function (DUF4139) MAG.T22.3_00226 1239962.C943_04443 1.9e-164 585.1 Bacteroidetes yicL Bacteria 4NJU1@976,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family MAG.T22.3_00227 1123057.P872_05055 1.7e-16 92.8 Cytophagia Bacteria 2DQHH@1,336VJ@2,47S0T@768503,4NWRV@976 NA|NA|NA MAG.T22.3_00228 1239962.C943_04436 6.8e-157 560.1 Cytophagia ecm27 ko:K07301 ko00000,ko02000 2.A.19.5 Bacteria 47K1Z@768503,4NFBC@976,COG0530@1,COG0530@2 NA|NA|NA P Sodium/calcium exchanger protein MAG.T22.3_00229 1239962.C943_04435 7.8e-197 693.0 Cytophagia dinB GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 ko:K02346 ko00000,ko01000,ko03400 Bacteria 47JB9@768503,4NF1Y@976,COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII MAG.T22.3_00230 1239962.C943_04434 4.6e-153 547.7 Cytophagia pabB 2.6.1.85,4.1.3.27,4.1.3.38 ko:K01657,ko:K01665,ko:K03342,ko:K13950 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716,R05553 RC00010,RC01418,RC01843,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 47K5D@768503,4NECR@976,COG0147@1,COG0147@2 NA|NA|NA EH Anthranilate para-aminobenzoate synthase component I MAG.T22.3_00231 1239962.C943_04433 2.9e-128 464.5 Bacteroidetes Bacteria 4NMFT@976,COG2353@1,COG2353@2 NA|NA|NA S Belongs to the UPF0312 family MAG.T22.3_00232 1239962.C943_04432 8.2e-64 250.0 Cytophagia dapH Bacteria 47PIB@768503,4NG6R@976,COG0663@1,COG0663@2 NA|NA|NA S carbonic anhydrase acetyltransferase MAG.T22.3_00233 1239962.C943_04431 2.6e-72 278.1 Cytophagia Bacteria 2DMXT@1,32UAK@2,47T4Y@768503,4NWD1@976 NA|NA|NA MAG.T22.3_00234 1239962.C943_04430 3.2e-143 514.2 Cytophagia ko:K07214 ko00000 Bacteria 47NH4@768503,4NGIA@976,COG2382@1,COG2382@2 NA|NA|NA P Putative esterase MAG.T22.3_00235 1239962.C943_04429 6.3e-187 659.8 Cytophagia Bacteria 47JY9@768503,4NFK1@976,COG0189@1,COG0189@2 NA|NA|NA HJ Glutathione synthase MAG.T22.3_00236 1239962.C943_04428 4.5e-213 746.9 Cytophagia ybdK GO:0003674,GO:0003824,GO:0016874,GO:0016879 ko:K06048 ko00000,ko01000 Bacteria 47KG2@768503,4NFFP@976,COG2170@1,COG2170@2 NA|NA|NA S ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity MAG.T22.3_00237 1239962.C943_04427 4.2e-155 553.9 Cytophagia 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 47NFG@768503,4NGC3@976,COG0518@1,COG0518@2 NA|NA|NA F Glutamine amidotransferase class-I MAG.T22.3_00238 1239962.C943_04426 6.2e-224 783.1 Cytophagia Bacteria 47K1S@768503,4NG4D@976,COG2308@1,COG2308@2 NA|NA|NA S Evidence 4 Homologs of previously reported genes of MAG.T22.3_00239 1239962.C943_04425 7.3e-141 506.5 Cytophagia Bacteria 47UUT@768503,4NNW5@976,COG3910@1,COG3910@2 NA|NA|NA S AAA ATPase domain MAG.T22.3_00242 1239962.C943_04422 2e-229 801.6 Cytophagia 3.4.13.19 ko:K01273 ko00000,ko00537,ko01000,ko01002,ko04147 Bacteria 47RS1@768503,4NI3V@976,COG2355@1,COG2355@2 NA|NA|NA E Membrane dipeptidase (Peptidase family M19) MAG.T22.3_00244 1239962.C943_04419 8.2e-269 932.6 Cytophagia ydaH ko:K12942 ko00000 Bacteria 47N1C@768503,4NH64@976,COG2978@1,COG2978@2 NA|NA|NA H AbgT putative transporter family MAG.T22.3_00245 1239962.C943_04417 1.8e-170 605.1 Cytophagia Bacteria 47SZ6@768503,4NI8T@976,COG2374@1,COG2374@2 NA|NA|NA L Endonuclease/Exonuclease/phosphatase family MAG.T22.3_00246 1239962.C943_04416 3.1e-167 594.3 Cytophagia 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47JC9@768503,4NF4A@976,COG3386@1,COG3386@2 NA|NA|NA G PFAM SMP-30 Gluconolaconase MAG.T22.3_00247 1239962.C943_04415 0.0 1223.8 Cytophagia MA20_01050 1.97.1.9 ko:K12527 ko00450,map00450 R07229 RC02420 ko00000,ko00001,ko01000 Bacteria 47KDW@768503,4NG9R@976,COG0493@1,COG0493@2,COG1143@1,COG1143@2 NA|NA|NA C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster MAG.T22.3_00248 1239962.C943_04414 0.0 1184.1 Cytophagia korA 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 47KM5@768503,4NEP3@976,COG0674@1,COG0674@2,COG1014@1,COG1014@2 NA|NA|NA C Pyruvate ferredoxin/flavodoxin oxidoreductase MAG.T22.3_00249 1239962.C943_04413 3e-198 697.6 Cytophagia MA20_01040 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 47KXJ@768503,4NIE0@976,COG1013@1,COG1013@2 NA|NA|NA C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MAG.T22.3_00250 1434325.AZQN01000005_gene3595 2.5e-30 137.9 Cytophagia ko:K19166 ko00000,ko01000,ko02048 Bacteria 47SBB@768503,4NVGW@976,COG4680@1,COG4680@2 NA|NA|NA S HigB_toxin, RelE-like toxic component of a toxin-antitoxin system MAG.T22.3_00251 1358423.N180_02935 2.4e-41 174.9 Sphingobacteriia ko:K18831 ko00000,ko02048,ko03000 Bacteria 1IYP6@117747,4NTXQ@976,COG5499@1,COG5499@2 NA|NA|NA K transcription regulator containing HTH domain MAG.T22.3_00252 1239962.C943_04412 3.4e-310 1070.1 Cytophagia Bacteria 47NIH@768503,4NIAB@976,COG0277@1,COG0277@2 NA|NA|NA C FAD binding domain MAG.T22.3_00253 1239962.C943_04411 6.2e-49 199.9 Cytophagia Bacteria 2DS5H@1,33EMJ@2,47T2A@768503,4NY2R@976 NA|NA|NA S Bor protein MAG.T22.3_00255 1239962.C943_04409 1.2e-104 386.0 Cytophagia Bacteria 47XFG@768503,4NNEU@976,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon MAG.T22.3_00256 1239962.C943_04408 7e-307 1059.3 Cytophagia Bacteria 47Q3Z@768503,4NI1V@976,COG0457@1,COG0457@2,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase MAG.T22.3_00257 1239962.C943_04406 7.4e-97 359.8 Cytophagia yfiT Bacteria 47QCG@768503,4NNQI@976,COG2318@1,COG2318@2 NA|NA|NA S DinB superfamily MAG.T22.3_00258 1189612.A33Q_2874 4.3e-67 261.9 Cytophagia Bacteria 2E29C@1,32XF2@2,47T1C@768503,4NSUT@976 NA|NA|NA MAG.T22.3_00259 1239962.C943_04403 0.0 1555.4 Cytophagia priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 47K5C@768503,4NFHB@976,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA MAG.T22.3_00260 1239962.C943_04402 0.0 1336.6 Cytophagia yyaL ko:K06888 ko00000 Bacteria 47M2A@768503,4NFE2@976,COG1331@1,COG1331@2 NA|NA|NA O COGs COG1331 Highly conserved protein containing a thioredoxin domain MAG.T22.3_00261 1239962.C943_04400 1.4e-184 652.1 Cytophagia Bacteria 47JI4@768503,4NFN6@976,COG2755@1,COG2755@2 NA|NA|NA E PFAM GSCFA family MAG.T22.3_00262 1235457.C404_02585 1e-11 76.6 Burkholderiaceae ko:K07274 ko00000,ko02000 9.B.99.1 Bacteria 1K7WY@119060,1N6RE@1224,2VW94@28216,COG4704@1,COG4704@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2141) MAG.T22.3_00263 1185876.BN8_01987 1.3e-87 329.7 Cytophagia ko:K07124 ko00000 Bacteria 47NIU@768503,4NK2T@976,COG0300@1,COG0300@2 NA|NA|NA S KR domain MAG.T22.3_00266 649349.Lbys_0134 9.8e-27 125.6 Cytophagia Bacteria 2DMVH@1,32TYD@2,47VWI@768503,4P54C@976 NA|NA|NA MAG.T22.3_00267 1239962.C943_04392 2.4e-107 394.8 Cytophagia fic ko:K04095 ko00000,ko03036 Bacteria 47SYE@768503,4NID4@976,COG2184@1,COG2184@2 NA|NA|NA D Fic/DOC family MAG.T22.3_00268 1239962.C943_04391 5.8e-174 616.7 Cytophagia 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 47MV6@768503,4NHPA@976,COG0451@1,COG0451@2 NA|NA|NA M Male sterility protein MAG.T22.3_00269 1239962.C943_04390 8.1e-166 589.7 Cytophagia Bacteria 47QEU@768503,4NIBZ@976,COG4461@1,COG4461@2 NA|NA|NA G 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process MAG.T22.3_00270 1239962.C943_04388 3e-109 401.4 Cytophagia Bacteria 47UWT@768503,4P3CI@976,COG5662@1,COG5662@2 NA|NA|NA K Domain of unknown function (DUF4349) MAG.T22.3_00271 1239962.C943_04387 1.5e-65 255.4 Cytophagia ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 47VB4@768503,4P3WU@976,COG2885@1,COG2885@2 NA|NA|NA M Protein of unknown function (DUF1573) MAG.T22.3_00272 1239962.C943_04386 8.5e-252 875.9 Cytophagia recD2_2 3.1.11.5 ko:K01144 ko00000,ko01000 Bacteria 47MBF@768503,4NDYK@976,COG0507@1,COG0507@2 NA|NA|NA L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member MAG.T22.3_00273 1239962.C943_04385 1.3e-90 339.0 Cytophagia FNV0100 Bacteria 47P7Y@768503,4NN73@976,COG1051@1,COG1051@2 NA|NA|NA F Nudix hydrolase MAG.T22.3_00274 1239962.C943_04384 1.1e-101 375.9 Cytophagia Bacteria 2C0G9@1,310GM@2,47NP8@768503,4NHU0@976 NA|NA|NA MAG.T22.3_00275 1239962.C943_04383 5.3e-136 490.3 Cytophagia Bacteria 2BUF6@1,32PR7@2,47UMT@768503,4PAVZ@976 NA|NA|NA S Protein of unknown function (DUF3822) MAG.T22.3_00276 1239962.C943_04382 3.2e-80 304.3 Cytophagia coaD 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 47PE3@768503,4NM84@976,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate MAG.T22.3_00277 1239962.C943_04381 2.1e-123 448.4 Cytophagia 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 47NQ9@768503,4NS9I@976,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain MAG.T22.3_00278 1239962.C943_04380 6.2e-114 416.8 Cytophagia pyrE 2.4.2.10,4.1.1.23 ko:K00762,ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15560 Bacteria 47JX7@768503,4NEF8@976,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) MAG.T22.3_00279 1239962.C943_04378 4.2e-141 507.3 Cytophagia nth 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 47K0Q@768503,4NE7K@976,COG0177@1,COG0177@2 NA|NA|NA L TIGRFAM TIGR02757 family protein MAG.T22.3_00280 1239962.C943_04377 2.2e-99 368.2 Cytophagia Bacteria 28PDU@1,2ZC5R@2,47PNQ@768503,4NND2@976 NA|NA|NA MAG.T22.3_00281 1239962.C943_04376 1.5e-187 662.1 Cytophagia ydjM 3.5.1.28 ko:K01448,ko:K01449,ko:K19223 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036 CBM50 Bacteria 47NR5@768503,4NG96@976,COG0797@1,COG0797@2,COG1388@1,COG1388@2 NA|NA|NA M PFAM LysM domain MAG.T22.3_00282 1239962.C943_04374 0.0 2021.5 Cytophagia Bacteria 47N25@768503,4NESU@976,COG4447@1,COG4447@2 NA|NA|NA S Sortilin, neurotensin receptor 3, MAG.T22.3_00284 1250232.JQNJ01000001_gene1553 8.9e-18 96.3 Flavobacteriia Bacteria 1I5MV@117743,4NUUE@976,COG3668@1,COG3668@2 NA|NA|NA S Pfam Plasmid stabilisation system protein MAG.T22.3_00285 1239962.C943_04373 9.3e-200 702.6 Cytophagia rfbB 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 47K3S@768503,4NE9V@976,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily MAG.T22.3_00286 1239962.C943_04372 2.7e-199 701.0 Cytophagia capI 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 R01385 RC00289 ko00000,ko00001,ko01000 Bacteria 47JU9@768503,4NEKA@976,COG0451@1,COG0451@2 NA|NA|NA M PFAM NAD dependent epimerase dehydratase family MAG.T22.3_00287 1239962.C943_04371 9.3e-217 759.2 Cytophagia Bacteria 47N4U@768503,4NEX8@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase 4-like MAG.T22.3_00288 1120965.AUBV01000010_gene2918 2.3e-22 110.9 Cytophagia ko:K07729 ko00000,ko03000 Bacteria 47S1R@768503,4NV53@976,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins MAG.T22.3_00289 1239962.C943_04369 2.1e-71 275.0 Bacteroidetes Bacteria 2BTXK@1,32P5R@2,4NSMQ@976 NA|NA|NA MAG.T22.3_00290 1239962.C943_04368 1.4e-58 232.3 Cytophagia Bacteria 2FKE3@1,34C1G@2,47W2F@768503,4P6C7@976 NA|NA|NA MAG.T22.3_00291 1239962.C943_04366 3.8e-145 520.8 Cytophagia proC GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0899,iIT341.HP1158,iSBO_1134.SBO_0282,ic_1306.c0493 Bacteria 47XP8@768503,4NE6F@976,COG0345@1,COG0345@2 NA|NA|NA E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline MAG.T22.3_00293 1239962.C943_04364 3.3e-124 451.1 Cytophagia hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0388 Bacteria 47M7D@768503,4NEEX@976,COG0106@1,COG0106@2 NA|NA|NA E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase MAG.T22.3_00294 1239962.C943_04363 6.7e-110 403.3 Cytophagia hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 iECED1_1282.ECED1_2372,iPC815.YPO1545,iYL1228.KPN_02479 Bacteria 47P9A@768503,4NF4J@976,COG0118@1,COG0118@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR MAG.T22.3_00295 1239962.C943_04362 1.8e-147 528.5 Cytophagia phhA GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0006082,GO:0006520,GO:0006558,GO:0006559,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016714,GO:0017144,GO:0019439,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222 1.14.16.1 ko:K00500 ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230 R01795,R07211 RC00490 ko00000,ko00001,ko01000 Bacteria 47KWF@768503,4NEX5@976,COG3186@1,COG3186@2 NA|NA|NA E PFAM Biopterin-dependent aromatic amino acid hydroxylase MAG.T22.3_00296 1239962.C943_04361 2.1e-188 664.8 Cytophagia aroF 2.5.1.54 ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 47KY7@768503,4NH82@976,COG2876@1,COG2876@2 NA|NA|NA E PFAM DAHP synthetase I family MAG.T22.3_00297 1239962.C943_04360 5e-126 457.2 Cytophagia trpA 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 47JYN@768503,4NE21@976,COG0159@1,COG0159@2 NA|NA|NA E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate MAG.T22.3_00298 1239962.C943_02067 5.7e-135 486.9 Cytophagia accD5 Bacteria 47JYJ@768503,4NEMJ@976,COG4799@1,COG4799@2 NA|NA|NA I Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) MAG.T22.3_00299 1239962.C943_02066 2.6e-152 544.7 Cytophagia Bacteria 47JJ3@768503,4NF8R@976,COG2912@1,COG2912@2 NA|NA|NA S Transglutaminase-like superfamily MAG.T22.3_00300 1239962.C943_02065 3.5e-92 344.4 Cytophagia Bacteria 47R9W@768503,4NSUU@976,COG0526@1,COG0526@2 NA|NA|NA CO AhpC/TSA family MAG.T22.3_00301 1239962.C943_00001 1.3e-114 419.1 Cytophagia acpT GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006553,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0019878,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.8.7 ko:K00997,ko:K06133 ko00770,map00770 R01625 RC00002 ko00000,ko00001,ko01000 iECNA114_1301.ECNA114_3584 Bacteria 47RPQ@768503,4NSBI@976,COG2091@1,COG2091@2 NA|NA|NA H Belongs to the P-Pant transferase superfamily MAG.T22.3_00302 1239962.C943_00002 2.9e-117 428.3 Cytophagia 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 47JUN@768503,4NH20@976,COG2319@1,COG2319@2 NA|NA|NA S PFAM WD domain, G-beta repeat MAG.T22.3_00303 1239962.C943_00003 1.8e-100 372.5 Cytophagia divIVA ko:K04074 ko00000,ko03036 Bacteria 47QRC@768503,4NQDF@976,COG3599@1,COG3599@2 NA|NA|NA D TIGRFAM DivIVA domain MAG.T22.3_00304 1239962.C943_00004 3.2e-59 234.2 Cytophagia folB 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01633,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503,R03504,R11037,R11073 RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 47QM5@768503,4NQ53@976,COG1539@1,COG1539@2 NA|NA|NA H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin MAG.T22.3_00305 1239962.C943_00005 1.8e-148 531.9 Cytophagia phuW Bacteria 47MCF@768503,4NEQ4@976,COG3016@1,COG3016@2 NA|NA|NA S Haem-binding uptake, Tiki superfamily, ChaN MAG.T22.3_00306 1239962.C943_00006 2.4e-83 314.7 Cytophagia Bacteria 2ATIR@1,31J2R@2,47QYN@768503,4NR1Z@976 NA|NA|NA S Domain of unknown function (DUF4268) MAG.T22.3_00307 1239962.C943_00010 6.1e-271 939.5 Bacteroidetes Bacteria 4NF3G@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase NAD-binding domain protein MAG.T22.3_00308 1239962.C943_00011 4e-22 110.2 Cytophagia Bacteria 2DI4K@1,3020V@2,47S4A@768503,4NV1J@976 NA|NA|NA S Protein of unknown function (DUF2892) MAG.T22.3_00309 1239962.C943_00012 3.9e-73 280.8 Bacteria ko:K09928 ko00000 Bacteria COG3216@1,COG3216@2 NA|NA|NA M Uncharacterized protein conserved in bacteria (DUF2062) MAG.T22.3_00310 1239962.C943_00013 1e-179 636.0 Cytophagia yjbM 2.7.6.5 ko:K07816 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 47P2Z@768503,4NFMF@976,COG2357@1,COG2357@2 NA|NA|NA S RelA SpoT domain protein MAG.T22.3_00311 1239962.C943_00014 1.8e-104 385.6 Cytophagia Bacteria 28JI1@1,2Z9BG@2,47Q2P@768503,4NMDW@976 NA|NA|NA MAG.T22.3_00312 1239962.C943_00016 9.2e-90 336.3 Cytophagia Bacteria 47XS3@768503,4NMPI@976,COG2335@1,COG2335@2 NA|NA|NA M Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. MAG.T22.3_00313 1239962.C943_00017 4.8e-74 283.9 Cytophagia Bacteria 47RNG@768503,4NQGU@976,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator MAG.T22.3_00314 1239962.C943_00018 1.1e-162 579.3 Cytophagia moaA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0030312,GO:0040007,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0071944,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22,4.6.1.17 ko:K03639,ko:K20967 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09394,R11372 RC03420,RC03425 ko00000,ko00001,ko01000 Bacteria 47K8J@768503,4NFS9@976,COG2896@1,COG2896@2 NA|NA|NA H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate MAG.T22.3_00315 1239962.C943_00019 1e-210 739.2 Cytophagia moeA 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 R09735 RC03462 ko00000,ko00001,ko01000 Bacteria 47M8R@768503,4NDYD@976,COG0303@1,COG0303@2 NA|NA|NA H Molybdenum cofactor synthesis domain protein MAG.T22.3_00316 1239962.C943_00020 1.9e-130 471.9 Cytophagia ko:K07090 ko00000 Bacteria 47P8A@768503,4NIJ9@976,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE MAG.T22.3_00317 1239962.C943_00021 7.3e-33 146.0 Cytophagia moaD ko:K03636 ko04122,map04122 ko00000,ko00001 Bacteria 47SRD@768503,4NXUN@976,COG1977@1,COG1977@2 NA|NA|NA H ThiS family MAG.T22.3_00318 1239962.C943_00022 4.2e-220 770.4 Cytophagia 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 R00552 RC00177 ko00000,ko00001,ko01000 Bacteria 47JM7@768503,4NHKZ@976,COG2235@1,COG2235@2 NA|NA|NA E Arginine deiminase MAG.T22.3_00319 1123057.P872_14820 1.4e-64 253.1 Cytophagia Bacteria 2DP33@1,330AX@2,47UFY@768503,4NX23@976 NA|NA|NA MAG.T22.3_00320 1239962.C943_00025 1.1e-310 1071.6 Bacteroidetes Bacteria 2DUH4@1,33QM8@2,4NPKV@976 NA|NA|NA MAG.T22.3_00321 1239962.C943_00026 6.5e-107 394.0 Cytophagia Bacteria 47RZH@768503,4NW8C@976,COG3595@1,COG3595@2 NA|NA|NA S Putative adhesin MAG.T22.3_00322 1239962.C943_00027 1.8e-63 248.4 Cytophagia Bacteria 47PUE@768503,4NWIC@976,COG2314@1,COG2314@2 NA|NA|NA S TM2 domain MAG.T22.3_00323 1189612.A33Q_1009 5.8e-47 193.4 Cytophagia Bacteria 2EBA7@1,32WYI@2,47X4Z@768503,4NTNU@976 NA|NA|NA S Protein of unknown function (DUF2752) MAG.T22.3_00324 1239962.C943_00029 6.8e-198 696.4 Cytophagia Bacteria 2DB8Y@1,2Z7TF@2,47MSP@768503,4NIJ2@976 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2236) MAG.T22.3_00325 1239962.C943_00030 4.9e-149 533.9 Cytophagia Bacteria 47R0N@768503,4NITC@976,COG0823@1,COG0823@2 NA|NA|NA U Involved in the tonB-independent uptake of proteins MAG.T22.3_00326 1239962.C943_00031 0.0 2443.3 Cytophagia purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 Bacteria 47NAM@768503,4NETY@976,COG0046@1,COG0046@2,COG0047@1,COG0047@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL MAG.T22.3_00327 1239962.C943_00032 0.0 1397.9 Cytophagia mrpA GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 ko:K05559,ko:K05565 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 47M8Q@768503,4NEBM@976,COG1009@1,COG1009@2,COG2111@1,COG2111@2 NA|NA|NA CP NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit MAG.T22.3_00328 1239962.C943_00033 6.8e-66 256.5 Cytophagia mnhB ko:K05559,ko:K05565,ko:K05566 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 47XSJ@768503,4NWKZ@976,COG2111@1,COG2111@2 NA|NA|NA P Domain related to MnhB subunit of Na+/H+ antiporter MAG.T22.3_00329 1239962.C943_00034 8.8e-54 216.1 Cytophagia mrpC ko:K05567 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 47R5U@768503,4NQ8N@976,COG1006@1,COG1006@2 NA|NA|NA P Multisubunit Na H antiporter MnhC subunit MAG.T22.3_00330 1239962.C943_00035 1.6e-272 944.9 Cytophagia mrpD GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 ko:K05568 ko00000,ko02000 2.A.63.1,2.A.63.2 iSB619.SA_RS04615 Bacteria 47YS2@768503,4PPTD@976,COG0651@1,COG0651@2 NA|NA|NA CP Proton-conducting membrane transporter MAG.T22.3_00331 1239962.C943_00036 8.8e-73 279.6 Cytophagia mrpE ko:K05569 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 47P8Q@768503,4NP56@976,COG1863@1,COG1863@2 NA|NA|NA P PFAM Na H ion antiporter subunit MAG.T22.3_00332 1239962.C943_00037 2e-37 161.4 Bacteria mnhF ko:K05570 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria COG2212@1,COG2212@2 NA|NA|NA P antiporter activity MAG.T22.3_00333 1239962.C943_00038 1.1e-55 222.6 Bacteroidetes mrpG ko:K05571 ko00000,ko02000 2.A.63.1,2.A.63.2 Bacteria 4NR0V@976,COG1320@1,COG1320@2 NA|NA|NA P monovalent cation proton antiporter, MnhG PhaG subunit MAG.T22.3_00334 1239962.C943_00039 1.3e-194 685.6 Cytophagia pgl 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 47KQB@768503,4NE87@976,COG2706@1,COG2706@2 NA|NA|NA G PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme MAG.T22.3_00335 1239962.C943_00040 9.2e-275 952.2 Cytophagia Bacteria 2BVKK@1,2Z8PC@2,47KVJ@768503,4NF9X@976 NA|NA|NA MAG.T22.3_00336 1239962.C943_00041 2.2e-27 127.9 Cytophagia cspB ko:K03704 ko00000,ko03000 Bacteria 47RX4@768503,4NURE@976,COG1278@1,COG1278@2 NA|NA|NA K Cold-shock protein MAG.T22.3_00337 1239962.C943_00042 1.9e-211 741.5 Cytophagia menC GO:0008150,GO:0040007 4.2.1.113 ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04031 RC01053 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0553 Bacteria 47KCD@768503,4NEBX@976,COG4948@1,COG4948@2 NA|NA|NA M PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal domain MAG.T22.3_00338 1239962.C943_00043 9.7e-233 812.4 Cytophagia queA 2.4.99.17 ko:K07568 ko00000,ko01000,ko03016 Bacteria 47KMT@768503,4NDZ5@976,COG0809@1,COG0809@2 NA|NA|NA J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) MAG.T22.3_00339 1239962.C943_00044 1.7e-72 278.5 Cytophagia ko:K07705 ko02020,map02020 M00492 ko00000,ko00001,ko00002,ko02022 Bacteria 47QJN@768503,4NQNB@976,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain MAG.T22.3_00340 1239962.C943_00045 6.5e-240 836.3 Bacteria Bacteria COG3829@1,COG3829@2 NA|NA|NA T transcription factor binding MAG.T22.3_00341 866536.Belba_3282 3.2e-14 84.3 Cytophagia Bacteria 2DY3Q@1,347Z3@2,47W00@768503,4P5A6@976 NA|NA|NA MAG.T22.3_00344 1517681.HW45_13060 5.1e-116 425.2 Vibrionales Bacteria 1MU82@1224,1RMHR@1236,1XWNT@135623,COG2015@1,COG2015@2 NA|NA|NA Q Alkyl sulfatase dimerisation MAG.T22.3_00346 1239962.C943_01037 5e-142 510.4 Cytophagia Bacteria 2EEX5@1,338QG@2,47W0B@768503,4NXEJ@976 NA|NA|NA S Protein of unknown function (DUF2490) MAG.T22.3_00347 1239962.C943_01036 5.6e-118 430.3 Cytophagia Bacteria 2ATWF@1,31JFP@2,47SD4@768503,4NQPB@976 NA|NA|NA MAG.T22.3_00348 1239962.C943_01035 8.7e-72 276.2 Bacteroidetes Bacteria 4NSEQ@976,COG3015@1,COG3015@2 NA|NA|NA MP lipoprotein NlpE involved in copper resistance MAG.T22.3_00349 1239962.C943_01034 0.0 1701.8 Cytophagia glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 R02111 ko00000,ko00001,ko01000 GT35 Bacteria 47JMN@768503,4NGR1@976,COG0058@1,COG0058@2 NA|NA|NA G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties MAG.T22.3_00350 1239962.C943_01032 1.9e-195 688.3 Cytophagia ko:K03668 ko00000 Bacteria 47K7R@768503,4NEY0@976,COG3187@1,COG3187@2 NA|NA|NA O Lipase (class 3) MAG.T22.3_00351 1239962.C943_01031 2e-101 375.2 Bacteroidetes Bacteria 4NQZ1@976,COG3247@1,COG3247@2 NA|NA|NA S Psort location CytoplasmicMembrane, score 10.00 MAG.T22.3_00352 1189612.A33Q_1132 3.5e-92 344.7 Cytophagia Bacteria 2DUYX@1,33T3A@2,47UD0@768503,4P1Y1@976 NA|NA|NA MAG.T22.3_00353 1239962.C943_01028 1e-154 552.7 Cytophagia gluQ 6.1.1.17 ko:K01885,ko:K01894 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Bacteria 47Q0Q@768503,4NP0Y@976,COG0008@1,COG0008@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family MAG.T22.3_00354 1239962.C943_01027 1.4e-69 268.9 Cytophagia Bacteria 47XTV@768503,4NN76@976,COG5642@1,COG5642@2 NA|NA|NA S Protein of unknown function (DUF2384) MAG.T22.3_00355 1239962.C943_01026 1.2e-79 302.4 Bacteria Bacteria COG5654@1,COG5654@2 NA|NA|NA S RES MAG.T22.3_00356 1239962.C943_01025 0.0 1230.7 Cytophagia serA GO:0003674,GO:0003824,GO:0004617,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008219,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0012501,GO:0016053,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0070905,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.399,1.1.1.95,3.1.3.3 ko:K00058,ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582,R01513 RC00017,RC00031 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 iYL1228.KPN_03348 Bacteria 47MQ2@768503,4NDVN@976,COG0111@1,COG0111@2,COG0560@1,COG0560@2 NA|NA|NA EH PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MAG.T22.3_00357 1239962.C943_01024 6.4e-79 300.1 Cytophagia 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 47PU7@768503,4NNUR@976,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain MAG.T22.3_00358 1239962.C943_01023 2.1e-98 365.2 Cytophagia 2.3.1.28 ko:K19271 br01600,ko00000,ko01000,ko01504 Bacteria 47PZ8@768503,4NPDG@976,COG4845@1,COG4845@2 NA|NA|NA V Chloramphenicol acetyltransferase MAG.T22.3_00359 1239962.C943_01022 6e-149 533.5 Cytophagia Bacteria 47PGN@768503,4P246@976,COG0457@1,COG0457@2 NA|NA|NA S Protein of unknown function (DUF2911) MAG.T22.3_00360 1239962.C943_01021 1.2e-145 522.7 Cytophagia ghrA 1.1.1.79,1.1.1.81 ko:K12972 ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120 R00465,R01388,R01392,R02527 RC00031,RC00042,RC00670 ko00000,ko00001,ko01000 Bacteria 47JBD@768503,4NE9J@976,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase MAG.T22.3_00361 1239962.C943_01020 9.9e-144 516.2 Cytophagia Bacteria 47Q8P@768503,4NQZP@976,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein family MAG.T22.3_00362 1239962.C943_01019 6.5e-24 117.9 Cytophagia Bacteria 47RDX@768503,4NSQG@976,COG0457@1,COG0457@2 NA|NA|NA S TPR repeat MAG.T22.3_00363 1239962.C943_01018 5.3e-184 650.2 Cytophagia holA 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 47M1Q@768503,4NEIB@976,COG1466@1,COG1466@2 NA|NA|NA L TIGRFAM DNA polymerase III, delta subunit MAG.T22.3_00364 1239962.C943_01017 0.0 1775.0 Cytophagia Bacteria 47JS4@768503,4NE4W@976,COG0457@1,COG0457@2,COG1729@1,COG1729@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.3_00365 1239962.C943_01016 0.0 1136.7 Cytophagia Bacteria 47Y4C@768503,4PKTX@976,COG4773@1,COG4773@2 NA|NA|NA P Receptor MAG.T22.3_00366 1239962.C943_01015 6e-132 476.9 Cytophagia rlpA ko:K03642 ko00000 Bacteria 47S99@768503,4NVU5@976,COG3087@1,COG3087@2 NA|NA|NA D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides MAG.T22.3_00367 1239962.C943_01014 6.1e-115 420.2 Cytophagia exbB ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 47N0M@768503,4NFIX@976,COG0811@1,COG0811@2 NA|NA|NA U PFAM MotA TolQ ExbB proton channel MAG.T22.3_00368 866536.Belba_3021 2e-54 218.4 Cytophagia exbD ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 47R2X@768503,4NNI6@976,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein ExbD TolR MAG.T22.3_00369 1239962.C943_01011 6e-113 414.1 Cytophagia tolA 2.7.13.3 ko:K03407,ko:K03646,ko:K06596,ko:K07277,ko:K12065,ko:K13593 ko02020,ko02025,ko02030,ko04112,map02020,map02025,map02030,map04112 M00506,M00507 ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035,ko02044,ko03029 1.B.33,2.C.1.2,3.A.7.11.1 Bacteria 47JDN@768503,4PKQP@976,COG3170@1,COG3170@2 NA|NA|NA NU Tfp pilus assembly protein FimV MAG.T22.3_00370 1239962.C943_01010 9e-221 772.7 Cytophagia folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0166,iSB619.SA_RS08370 Bacteria 47K0F@768503,4NES8@976,COG0285@1,COG0285@2 NA|NA|NA H Belongs to the folylpolyglutamate synthase family MAG.T22.3_00371 1239962.C943_01009 4.4e-115 420.6 Cytophagia trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33 ko:K02493,ko:K03439 R10806 RC00003,RC03279 ko00000,ko01000,ko03012,ko03016 Bacteria 47JY6@768503,4NG4V@976,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA MAG.T22.3_00372 1239962.C943_01008 6e-72 276.9 Cytophagia paiA Bacteria 47QAW@768503,4NQVT@976,COG0454@1,COG0456@2 NA|NA|NA K PFAM GCN5-related N-acetyltransferase MAG.T22.3_00373 1239962.C943_01006 0.0 1869.7 Bacteroidetes ko:K03931 ko00000 GH63 Bacteria 4NIK8@976,COG3408@1,COG3408@2 NA|NA|NA G Trehalase MAG.T22.3_00374 1239962.C943_01005 0.0 1743.8 Cytophagia Bacteria 47TU9@768503,4NJRT@976,COG1262@1,COG1262@2 NA|NA|NA S Sulfatase-modifying factor enzyme 1 MAG.T22.3_00375 1239962.C943_01004 3.7e-59 234.2 Cytophagia prfA GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02835,ko:K15034 ko00000,ko03012 Bacteria 47YSM@768503,4PPXH@976,COG0216@1,COG0216@2 NA|NA|NA J RF-1 domain MAG.T22.3_00376 1239962.C943_01003 1.6e-244 851.7 Cytophagia oprM ko:K18139 ko01501,ko02024,map01501,map02024 M00642,M00643,M00647,M00718,M00768,M00822 ko00000,ko00001,ko00002,ko01504,ko02000 1.B.17,2.A.6.2 Bacteria 47KN4@768503,4NDZK@976,COG1538@1,COG1538@2 NA|NA|NA MU TIGRFAM efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family MAG.T22.3_00377 1239962.C943_01002 0.0 1929.1 Cytophagia ko:K03296 ko00000 2.A.6.2 Bacteria 47JGB@768503,4NDZG@976,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T22.3_00378 1239962.C943_01001 5.1e-183 647.1 Cytophagia ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 Bacteria 47M9U@768503,4NIDC@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.3_00379 1239962.C943_01000 6.6e-136 490.0 Cytophagia 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003 GT2 Bacteria 47YQ5@768503,4PMSM@976,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 2 MAG.T22.3_00380 1239962.C943_00999 0.0 1346.3 Cytophagia 2.4.2.43 ko:K07264 ko01503,map01503 M00721 R09773,R09774,R09781 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Bacteria 47XJR@768503,4NE7V@976,COG1807@1,COG1807@2,COG3952@1,COG3952@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase MAG.T22.3_00381 1239962.C943_00998 1.3e-117 429.1 Cytophagia Bacteria 47NIM@768503,4NGI5@976,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal MAG.T22.3_00382 1239962.C943_00997 9e-227 792.7 Cytophagia Bacteria 47NRA@768503,4NEIS@976,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T22.3_00383 1239962.C943_00996 0.0 1908.3 Cytophagia ko:K15726 ko00000,ko02000 2.A.6.1.2 Bacteria 47JC4@768503,4P36A@976,COG3696@1,COG3696@2 NA|NA|NA P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T22.3_00384 1239962.C943_00995 4.5e-214 750.4 Cytophagia czcC ko:K15725,ko:K15726 ko00000,ko02000 1.B.17.2.2,2.A.6.1.2 Bacteria 47XCX@768503,4NNSZ@976,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein MAG.T22.3_00385 1239962.C943_00994 8.8e-196 689.5 Cytophagia ko:K15727 ko00000,ko02000 8.A.1.2.1 Bacteria 47JRK@768503,4NDW5@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.3_00386 1239962.C943_00993 0.0 1531.2 Cytophagia 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 47JYI@768503,4NERM@976,COG0474@1,COG0474@2 NA|NA|NA P ATPase, P-type (transporting), HAD superfamily, subfamily IC MAG.T22.3_00387 1239962.C943_00992 2.9e-99 367.9 Cytophagia Bacteria 2C852@1,32YB2@2,47S6T@768503,4NM63@976 NA|NA|NA S Domain of unknown function (DUF4136) MAG.T22.3_00388 1239962.C943_00991 1.2e-95 355.9 Bacteroidetes ko:K07275 ko00000 Bacteria 4NWCT@976,COG3047@1,COG3047@2 NA|NA|NA MAG.T22.3_00389 1202532.FF52_15667 3e-44 185.3 Flavobacterium Bacteria 1ID5S@117743,28N4A@1,2NXF4@237,2ZB9T@2,4PJ7Q@976 NA|NA|NA S Domain of unknown function (DUF4136) MAG.T22.3_00390 1239962.C943_00980 0.0 1388.6 Cytophagia ko:K02030,ko:K20971 ko02025,map02025 M00236 ko00000,ko00001,ko00002,ko01001,ko02000,ko02022 3.A.1.3 Bacteria 47TDR@768503,4NDXU@976,COG0642@1,COG0784@1,COG0784@2,COG2205@2 NA|NA|NA T 7TMR-DISM extracellular 2 MAG.T22.3_00391 1239962.C943_00979 8.4e-162 576.2 Cytophagia mmgB 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 Bacteria 47PSZ@768503,4NGU8@976,COG1250@1,COG1250@2 NA|NA|NA I 3-hydroxyacyl-CoA dehydrogenase MAG.T22.3_00392 1239962.C943_00978 3.1e-184 651.0 Cytophagia Bacteria 47KVW@768503,4NFE7@976,COG3173@1,COG3173@2 NA|NA|NA S Phosphotransferase enzyme family MAG.T22.3_00393 1239962.C943_00977 8.1e-224 782.7 Cytophagia fadE1 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 47MEG@768503,4NH3I@976,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA dehydrogenase, C-terminal domain MAG.T22.3_00394 1239962.C943_00976 6.9e-136 490.0 Cytophagia Bacteria 47MT3@768503,4NEUB@976,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T22.3_00395 1239962.C943_00974 9.2e-170 602.8 Cytophagia Bacteria 47KRH@768503,4NIQ5@976,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase MAG.T22.3_00396 1239962.C943_00973 5.6e-189 666.8 Cytophagia Bacteria 28H6T@1,2Z7J4@2,47K71@768503,4NE4C@976 NA|NA|NA MAG.T22.3_00397 1239962.C943_00972 4.4e-52 210.3 Cytophagia Bacteria 47S3H@768503,4NUYS@976,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T22.3_00398 866536.Belba_2645 8.9e-34 150.2 Cytophagia Bacteria 2DJUE@1,32UDV@2,47R9Q@768503,4NUBK@976 NA|NA|NA MAG.T22.3_00399 1239962.C943_00970 0.0 1923.3 Cytophagia ko:K07289,ko:K09800 ko00000,ko02000 Bacteria 47KBD@768503,4NEJQ@976,COG2982@1,COG2982@2 NA|NA|NA M AsmA-like C-terminal region MAG.T22.3_00400 1239962.C943_00969 2.2e-94 351.7 Cytophagia 5.2.1.8 ko:K03768 ko00000,ko01000,ko03110 Bacteria 47PB6@768503,4NMG5@976,COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides MAG.T22.3_00401 1288963.ADIS_2355 0.0 2543.5 Cytophagia cas9 ko:K09952 ko00000,ko01000,ko02048 Bacteria 47TU8@768503,4NFM9@976,COG3513@1,COG3513@2 NA|NA|NA L Bridge helix of CRISPR-associated endonuclease Cas9 MAG.T22.3_00402 866536.Belba_3200 1.9e-90 338.6 Cytophagia Bacteria 47RHZ@768503,4NPWC@976,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like MAG.T22.3_00403 1189612.A33Q_2776 6.8e-143 513.5 Cytophagia cas1 ko:K15342 ko00000,ko02048,ko03400 Bacteria 47PZS@768503,4NEKQ@976,COG1518@1,COG1518@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette MAG.T22.3_00404 1288963.ADIS_2358 6.2e-52 209.9 Cytophagia cas2 ko:K09951 ko00000,ko02048 Bacteria 47V8J@768503,4NQ8Z@976,COG3512@1,COG3512@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette MAG.T22.3_00405 641524.ADICYQ_4932 9.3e-133 479.9 Cytophagia ko:K07486 ko00000 Bacteria 47NU4@768503,4NKDC@976,COG3547@1,COG3547@2 NA|NA|NA L PFAM transposase IS116 IS110 IS902 family MAG.T22.3_00407 1239962.C943_02642 1.3e-148 532.3 Cytophagia ycbX GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009636,GO:0009987,GO:0019748,GO:0042221,GO:0044237,GO:0044248,GO:0050896,GO:0098754 ko:K07140 ko00000 Bacteria 47PMH@768503,4NG33@976,COG3217@1,COG3217@2 NA|NA|NA S beta barrel domain MAG.T22.3_00408 1239962.C943_02644 0.0 1936.4 Cytophagia Bacteria 47KKX@768503,4NDXS@976,COG1629@1,COG1629@2 NA|NA|NA P PFAM TonB-dependent Receptor Plug MAG.T22.3_00409 1239962.C943_02645 1.4e-281 974.9 Cytophagia ko:K21572 ko00000,ko02000 8.A.46.1,8.A.46.3 Bacteria 47M0V@768503,4NE4Y@976,COG3637@1,COG3637@2 NA|NA|NA M RagB SusD domain protein MAG.T22.3_00410 1239962.C943_02646 0.0 2184.5 Cytophagia Bacteria 47U55@768503,4NEE8@976,COG4888@1,COG4888@2 NA|NA|NA S ASPIC and UnbV MAG.T22.3_00411 1239962.C943_02647 2.5e-93 348.2 Cytophagia Bacteria 2BTVE@1,32P38@2,47PZ2@768503,4NRR1@976 NA|NA|NA MAG.T22.3_00412 1239962.C943_02648 0.0 2186.4 Cytophagia Bacteria 47M08@768503,4NEE8@976,COG4888@1,COG4888@2 NA|NA|NA S ASPIC UnbV domain protein MAG.T22.3_00413 1239962.C943_02650 0.0 2023.8 Cytophagia Bacteria 47MGE@768503,4NEE8@976,COG4888@1,COG4888@2 NA|NA|NA S ASPIC and UnbV MAG.T22.3_00414 1239962.C943_02652 7.9e-252 875.9 Cytophagia Bacteria 47JAV@768503,4NF9W@976,COG0671@1,COG0671@2 NA|NA|NA I PAP2 superfamily MAG.T22.3_00415 1239962.C943_02654 1.8e-113 415.2 Cytophagia rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 ko00000,ko01000,ko03009,ko03036 Bacteria 47KEA@768503,4NEJG@976,COG0357@1,COG0357@2 NA|NA|NA J Specifically methylates the N7 position of a guanine in 16S rRNA MAG.T22.3_00416 1239962.C943_02657 2.1e-173 615.1 Cytophagia MA20_41055 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 47UN9@768503,4NN3B@976,COG0628@1,COG0628@2 NA|NA|NA S Pfam:UPF0118 MAG.T22.3_00417 1239962.C943_02658 8.8e-182 642.9 Cytophagia 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria 47TDC@768503,4NE1P@976,COG4409@1,COG4409@2,COG4692@1,COG4692@2 NA|NA|NA G BNR repeat-like domain MAG.T22.3_00418 866536.Belba_0449 6.1e-163 580.5 Cytophagia ko:K07133 ko00000 Bacteria 47P2P@768503,4NE3E@976,COG1373@1,COG1373@2 NA|NA|NA S AAA domain MAG.T22.3_00419 1239962.C943_02659 0.0 2823.1 Cytophagia dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 47K9H@768503,4NFA0@976,COG0587@1,COG0587@2 NA|NA|NA L DNA-directed DNA polymerase MAG.T22.3_00420 1239962.C943_02660 3e-53 214.2 Cytophagia trxA ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 47QDT@768503,4NQ5B@976,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family MAG.T22.3_00421 1239962.C943_02661 1.8e-179 635.2 Cytophagia selU GO:0001887,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016785,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043828,GO:0044237,GO:0044238,GO:0046483,GO:0070329,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 ko:K06917 ko00000,ko01000,ko03016 Bacteria 47KFW@768503,4NH7W@976,COG2603@1,COG2603@2 NA|NA|NA S Rhodanese Homology Domain MAG.T22.3_00422 1239962.C943_02662 9e-179 632.9 Cytophagia selD GO:0000287,GO:0001887,GO:0003674,GO:0003824,GO:0004756,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009451,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019752,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0070329,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 iPC815.YPO2164,iSFV_1184.SFV_1453,iSF_1195.SF1459,iSFxv_1172.SFxv_1645,iS_1188.S1574 Bacteria 47JJA@768503,4NI4R@976,COG0709@1,COG0709@2 NA|NA|NA E Synthesizes selenophosphate from selenide and ATP MAG.T22.3_00423 1239962.C943_02663 6e-114 416.8 Cytophagia polX ko:K02347,ko:K04477 ko00000,ko03400 Bacteria 47PG3@768503,4NMBC@976,COG1387@1,COG1387@2 NA|NA|NA E Domain of Unknown Function (DUF1080) MAG.T22.3_00424 1239962.C943_02664 9.6e-95 352.8 Cytophagia YH67_14670 Bacteria 47QB1@768503,4NR4F@976,COG2928@1,COG2928@2 NA|NA|NA S Protein of unknown function (DUF502) MAG.T22.3_00425 1239962.C943_02665 3.4e-93 347.8 Cytophagia nqrE GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 ko:K00350 ko00000,ko01000 Bacteria 47KRI@768503,4NEU0@976,COG2209@1,COG2209@2 NA|NA|NA C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol MAG.T22.3_00426 1239962.C943_02666 4.6e-115 420.6 Bacteroidetes nqrD GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.8 ko:K00349 ko00000,ko01000 Bacteria 4NGD9@976,COG1347@1,COG1347@2 NA|NA|NA C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol MAG.T22.3_00427 1239962.C943_02667 1.7e-121 442.2 Bacteroidetes nqrC GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.6.5.8 ko:K00348 ko00000,ko01000 Bacteria 4NF7A@976,COG2869@1,COG2869@2 NA|NA|NA C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol MAG.T22.3_00428 1239962.C943_02668 8.7e-218 762.7 Cytophagia nqrB 1.6.5.8 ko:K00347 ko00000,ko01000 Bacteria 47ND4@768503,4NFGW@976,COG4658@1,COG4658@2 NA|NA|NA C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol MAG.T22.3_00429 1239962.C943_02669 2.2e-249 867.8 Cytophagia nqrA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 ko:K00346 ko00000,ko01000 Bacteria 47M23@768503,4NEDQ@976,COG1726@1,COG1726@2 NA|NA|NA C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol MAG.T22.3_00430 1239962.C943_02670 2.2e-165 588.2 Cytophagia ispH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.4,2.7.4.25 ko:K00945,ko:K02945,ko:K03527 ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010 M00052,M00096,M00178 R00158,R00512,R01665,R05884,R08210 RC00002,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 iECIAI1_1343.ECIAI1_0030,iECW_1372.ECW_m0028,iEKO11_1354.EKO11_3884,iEcHS_1320.EcHS_A0031,iEcolC_1368.EcolC_3626,iIT341.HP0400,iLJ478.TM1444,iPC815.YPO0477,iSFV_1184.SFV_0023,iSF_1195.SF0026,iSFxv_1172.SFxv_0027,iS_1188.S0028,iWFL_1372.ECW_m0028,iYL1228.KPN_00024 Bacteria 47KQ3@768503,4NDUX@976,COG0761@1,COG0761@2 NA|NA|NA IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis MAG.T22.3_00431 1239962.C943_02671 2.1e-112 411.8 Cytophagia cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.19,2.7.4.25,6.3.2.1 ko:K00800,ko:K00945,ko:K03977,ko:K13799 ko00240,ko00400,ko00410,ko00770,ko01100,ko01110,ko01130,ko01230,map00240,map00400,map00410,map00770,map01100,map01110,map01130,map01230 M00022,M00052,M00119 R00158,R00512,R01665,R02473,R03460 RC00002,RC00096,RC00141,RC00350 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 47K5Q@768503,4NEMB@976,COG0283@1,COG0283@2 NA|NA|NA F Belongs to the cytidylate kinase family. Type 1 subfamily MAG.T22.3_00432 1239962.C943_02673 7.2e-292 1009.2 Cytophagia ade GO:0000034,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005506,GO:0006040,GO:0006044,GO:0006046,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008448,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016787,GO:0016810,GO:0016811,GO:0016814,GO:0018130,GO:0019213,GO:0019239,GO:0019438,GO:0019439,GO:0030145,GO:0034641,GO:0042221,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046348,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055086,GO:0055114,GO:0070887,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0097237,GO:0098754,GO:0098869,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1990748 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 R01244 RC00477 ko00000,ko00001,ko01000 iECUMN_1333.ECUMN_4192,iSFV_1184.SFV_3844,iYO844.BSU14520 Bacteria 47KX0@768503,4NFD9@976,COG1001@1,COG1001@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family MAG.T22.3_00433 1094466.KQS_00565 8.5e-92 344.7 Flavobacterium Bacteria 1IDD4@117743,2NY1Z@237,4PAC5@976,COG5635@1,COG5635@2 NA|NA|NA T NACHT domain MAG.T22.3_00434 1239962.C943_02674 9.8e-61 239.2 Cytophagia yraN ko:K07460 ko00000 Bacteria 47QW9@768503,4NS7E@976,COG0792@1,COG0792@2 NA|NA|NA L Belongs to the UPF0102 family MAG.T22.3_00435 1239962.C943_02675 4.5e-129 467.2 Cytophagia lipB GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 ko:K03644,ko:K03801 ko00785,ko01100,map00785,map01100 R07766,R07767,R07768,R07769 RC00039,RC00992,RC01978,RC02867 ko00000,ko00001,ko01000 Bacteria 47KKV@768503,4NE14@976,COG0321@1,COG0321@2 NA|NA|NA H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate MAG.T22.3_00436 1239962.C943_02676 6.5e-69 266.5 Cytophagia Bacteria 2AGNU@1,316WB@2,47RK1@768503,4NSNZ@976 NA|NA|NA MAG.T22.3_00437 1239962.C943_02677 3.2e-138 497.7 Cytophagia polB 2.7.7.7 ko:K02336,ko:K07501 ko00000,ko01000,ko03400 Bacteria 47KCR@768503,4PKQ5@976,COG0417@1,COG0417@2 NA|NA|NA L 3'-5' exonuclease related to the exonuclease domain of PolB MAG.T22.3_00439 1239962.C943_02680 4.9e-64 250.4 Cytophagia vapC ko:K18828 ko00000,ko01000,ko02048,ko03016 Bacteria 47VW3@768503,4NSWG@976,COG1487@1,COG1487@2 NA|NA|NA S PIN domain MAG.T22.3_00440 1239962.C943_02681 0.0 1446.4 Cytophagia rnr ko:K12573,ko:K12585 ko03018,map03018 M00391 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 47JK7@768503,4NE7T@976,COG0557@1,COG0557@2 NA|NA|NA J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs MAG.T22.3_00441 1239962.C943_02682 1.2e-177 629.0 Cytophagia idsA 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13787,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00365,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 47JRS@768503,4NEGQ@976,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family MAG.T22.3_00442 1239962.C943_02683 2.8e-111 407.9 Cytophagia Bacteria 47N8U@768503,4NECA@976,COG0705@1,COG0705@2 NA|NA|NA S PFAM Rhomboid family MAG.T22.3_00443 1239962.C943_02684 1.2e-49 202.2 Bacteria hpf ko:K05808,ko:K05809 ko00000,ko03009 Bacteria COG1544@1,COG1544@2 NA|NA|NA J regulation of translation MAG.T22.3_00444 1239962.C943_02685 0.0 2056.2 Cytophagia Bacteria 47M5A@768503,4NESU@976,COG4447@1,COG4447@2 NA|NA|NA S Sortilin, neurotensin receptor 3, MAG.T22.3_00445 1120968.AUBX01000011_gene3318 1e-35 155.6 Cytophagia rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47R69@768503,4NS7T@976,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family MAG.T22.3_00446 1239962.C943_02687 5.8e-49 199.9 Cytophagia rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47R7R@768503,4NSHE@976,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 MAG.T22.3_00448 1239962.C943_02689 8.1e-190 669.5 Cytophagia nrdB 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iJN746.PP_1177 Bacteria 47MSG@768503,4NG18@976,COG0208@1,COG0208@2 NA|NA|NA F reductase, small chain MAG.T22.3_00449 1239962.C943_02690 0.0 1619.0 Cytophagia nrdA GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 47JEH@768503,4NEHQ@976,COG0209@1,COG0209@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides MAG.T22.3_00451 1239962.C943_01324 0.0 2205.3 Cytophagia Bacteria 47NMF@768503,4NESU@976,COG4447@1,COG4447@2 NA|NA|NA G Sortilin, neurotensin receptor 3, MAG.T22.3_00452 1239962.C943_01325 0.0 1122.8 Cytophagia ggt_1 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 Bacteria 47K06@768503,4NF2H@976,COG0405@1,COG0405@2 NA|NA|NA E Gamma-glutamyltranspeptidase MAG.T22.3_00453 1239962.C943_01326 9.3e-75 286.2 Bacteroidetes Bacteria 2APQJ@1,31EUD@2,4NNU5@976 NA|NA|NA MAG.T22.3_00454 1239962.C943_01327 2.4e-125 454.9 Cytophagia nagB 3.1.1.31,3.5.99.6 ko:K01057,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 47PHR@768503,4NFCM@976,COG0363@1,COG0363@2 NA|NA|NA G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase MAG.T22.3_00455 1239962.C943_01329 1.4e-229 802.0 Cytophagia Bacteria 47K89@768503,4NEYR@976,COG0738@1,COG0738@2 NA|NA|NA G TIGRFAM glucose galactose transporter MAG.T22.3_00456 1239962.C943_01330 2.1e-205 721.5 Cytophagia nagA 3.5.1.25,3.5.99.6 ko:K01443,ko:K02564 ko00520,ko01100,ko01130,map00520,map01100,map01130 R00765,R02059 RC00163,RC00166,RC00300 ko00000,ko00001,ko01000 Bacteria 47KJ5@768503,4NJ35@976,COG1820@1,COG1820@2 NA|NA|NA G Belongs to the metallo-dependent hydrolases superfamily. NagA family MAG.T22.3_00457 1239962.C943_01331 2.1e-249 867.8 Bacteroidetes Bacteria 4NF96@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase domain protein MAG.T22.3_00458 1239962.C943_01332 1.9e-129 468.8 Cytophagia Bacteria 47KTV@768503,4NGKU@976,COG4299@1,COG4299@2 NA|NA|NA S Domain of unknown function (DUF5009) MAG.T22.3_00459 1239962.C943_01333 1.6e-169 602.1 Cytophagia Bacteria 47MBN@768503,4NHFK@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.3_00460 1239962.C943_01334 0.0 1375.1 Cytophagia 3.4.14.5 ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Bacteria 47KF8@768503,4NETS@976,COG0823@1,COG0823@2,COG1506@1,COG1506@2 NA|NA|NA EU Dipeptidyl peptidase IV (DPP IV) N-terminal region MAG.T22.3_00462 1239962.C943_01638 8.5e-309 1065.4 Cytophagia Bacteria 47K4K@768503,4NGUB@976,COG0308@1,COG0308@2 NA|NA|NA E Peptidase M1, membrane alanine aminopeptidase MAG.T22.3_00463 1239962.C943_01639 1.3e-262 911.8 Cytophagia Bacteria 47M9C@768503,4NF4Q@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase domain protein MAG.T22.3_00464 1239962.C943_01640 2.6e-68 264.6 Bacteroidetes Bacteria 2FBET@1,343KB@2,4P57G@976 NA|NA|NA MAG.T22.3_00465 1239962.C943_01641 4.8e-61 240.4 Bacteroidetes Bacteria 2EG2A@1,339UA@2,4NY18@976 NA|NA|NA MAG.T22.3_00466 1239962.C943_01644 8.4e-99 366.3 Cytophagia Bacteria 28H95@1,2Z7KY@2,47KWH@768503,4NG37@976 NA|NA|NA S Protein of unknown function (DUF4256) MAG.T22.3_00467 1239962.C943_01645 2.2e-229 801.2 Cytophagia yciC Bacteria 47MHA@768503,4NENH@976,COG0523@1,COG0523@2 NA|NA|NA S Cobalamin synthesis protein cobW C-terminal domain MAG.T22.3_00468 1239962.C943_01646 1.2e-171 609.0 Bacteroidetes ndvB 2.4.1.12,3.2.1.58 ko:K00694,ko:K01210 ko00500,ko01100,ko02026,map00500,map01100,map02026 R00308,R02889,R03115 RC00005,RC00467 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.3.1.2,4.D.3.1.5,4.D.3.1.6 GT2 Bacteria 4NIVF@976,COG5309@1,COG5309@2 NA|NA|NA G Glycosyl hydrolases family 17 MAG.T22.3_00469 1239962.C943_01647 0.0 1485.7 Bacteroidetes ndvB 2.4.1.12,3.2.1.58 ko:K00694,ko:K01210,ko:K03292 ko00500,ko01100,ko02026,map00500,map01100,map02026 R00308,R02889,R03115 RC00005,RC00467 ko00000,ko00001,ko01000,ko01003,ko02000 2.A.2,4.D.3.1.2,4.D.3.1.5,4.D.3.1.6 GT2 Bacteria 4NE3B@976,COG2211@1,COG2211@2,COG5309@1,COG5309@2 NA|NA|NA G Transporter MAG.T22.3_00470 1239962.C943_01648 3e-240 837.4 Bacteroidetes Bacteria 4NFD7@976,COG5309@1,COG5309@2 NA|NA|NA G Glycosyl hydrolases family 17 MAG.T22.3_00471 1239962.C943_01649 7.2e-311 1072.4 Cytophagia 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 GH3 Bacteria 47XBT@768503,4NJGK@976,COG1472@1,COG1472@2 NA|NA|NA G Glycosyl hydrolase family 3 C-terminal domain MAG.T22.3_00472 1239962.C943_01650 0.0 2161.0 Bacteroidetes Bacteria 28HKI@1,2Z7VC@2,4NFS2@976 NA|NA|NA MAG.T22.3_00473 1239962.C943_01651 0.0 1567.7 Cytophagia chiA 3.2.1.73 ko:K01216 ko00000,ko01000 Bacteria 47YQN@768503,4PPR2@976,COG2273@1,COG2273@2,COG3291@1,COG3291@2,COG4257@1,COG4257@2 NA|NA|NA V antibiotic catabolic process MAG.T22.3_00474 1239962.C943_01652 3.6e-162 577.4 Cytophagia Bacteria 47URJ@768503,4NHP5@976,COG2273@1,COG2273@2 NA|NA|NA G Glycosyl hydrolases family 16 MAG.T22.3_00475 1239962.C943_01653 4e-262 910.2 Bacteroidetes Bacteria 4PM9P@976,COG5492@1,COG5492@2 NA|NA|NA N domain, Protein MAG.T22.3_00476 1239962.C943_01654 0.0 2104.3 Bacteroidetes 3.2.1.89 ko:K01224 ko00000,ko01000 Bacteria 4NGEN@976,COG3250@1,COG3250@2 NA|NA|NA G beta-galactosidase activity MAG.T22.3_00481 1239962.C943_02810 9.4e-105 386.3 Cytophagia batE Bacteria 47P4Z@768503,4NIH7@976,COG3103@1,COG3103@2 NA|NA|NA T Sh3 type 3 domain protein MAG.T22.3_00482 1239962.C943_02811 7.7e-109 399.8 Cytophagia lonD 3.4.21.53 ko:K01338,ko:K07157 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria 47NJ0@768503,4NEJU@976,COG2802@1,COG2802@2 NA|NA|NA S Peptidase S16, lon domain protein MAG.T22.3_00483 1239962.C943_02812 1.1e-189 669.1 Cytophagia gapA GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iAPECO1_1312.APECO1_847,iPC815.YPO2157,iUTI89_1310.UTI89_C1975,ic_1306.c2184 Bacteria 47N0V@768503,4NEMF@976,COG0057@1,COG0057@2 NA|NA|NA G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family MAG.T22.3_00484 1239962.C943_02813 2.4e-156 558.1 Cytophagia yicC ko:K03316 ko00000 2.A.36 Bacteria 47JXA@768503,4NEU4@976,COG1561@1,COG1561@2 NA|NA|NA S PFAM YicC-like family, N-terminal region MAG.T22.3_00485 1239962.C943_02814 0.0 2214.1 Cytophagia ko:K03641,ko:K07277 ko00000,ko02000,ko03029 1.B.33,2.C.1.2 Bacteria 47KAC@768503,4NERT@976,COG0823@1,COG0823@2,COG4775@1,COG4775@2 NA|NA|NA MU PFAM WD40-like beta Propeller MAG.T22.3_00486 1239962.C943_02815 4.8e-188 663.7 Cytophagia mnmC GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 ko:K15461 R00601,R08702 RC00003,RC00053,RC00060,RC01483 ko00000,ko01000,ko03016 Bacteria 47JI9@768503,4NFCD@976,COG0665@1,COG0665@2 NA|NA|NA E PFAM FAD dependent oxidoreductase MAG.T22.3_00487 1239962.C943_02816 3.2e-113 414.5 Cytophagia ycbL GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 ko:K01069 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000 Bacteria 47PA3@768503,4NE2Y@976,COG0491@1,COG0491@2 NA|NA|NA P PFAM Metallo-beta-lactamase superfamily MAG.T22.3_00488 1239962.C943_02817 3.6e-107 394.4 Cytophagia pssA 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 Bacteria 47PCF@768503,4NNUZ@976,COG1183@1,COG1183@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family MAG.T22.3_00489 1239962.C943_02818 0.0 1949.9 Bacteroidetes porU Bacteria 4NDY7@976,COG1572@1,COG1572@2 NA|NA|NA S Peptidase family C25 MAG.T22.3_00490 1239962.C943_02819 4.2e-228 797.0 Cytophagia porV Bacteria 47KQT@768503,4NDZW@976,COG2067@1,COG2067@2 NA|NA|NA I long-chain fatty acid transport protein MAG.T22.3_00491 1239962.C943_02820 5.9e-225 786.6 Cytophagia ko:K07263 ko00000,ko01000,ko01002 Bacteria 47JF1@768503,4NEPT@976,COG0612@1,COG0612@2 NA|NA|NA S PFAM Peptidase M16 inactive domain MAG.T22.3_00492 1239962.C943_02821 3.5e-169 600.9 Cytophagia Bacteria 47MWK@768503,4NJQR@976,COG1216@1,COG1216@2 NA|NA|NA S PFAM Glycosyl transferase family 2 MAG.T22.3_00493 1239962.C943_02822 1.5e-101 375.6 Cytophagia yigZ 2.1.1.45,3.4.13.9 ko:K00560,ko:K01271 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 47P9D@768503,4NF0D@976,COG1739@1,COG1739@2 NA|NA|NA S PFAM Uncharacterised protein family UPF0029, Impact, N-terminal MAG.T22.3_00494 1239962.C943_02823 1.9e-104 385.2 Cytophagia rnd 3.1.13.5,3.6.4.12 ko:K03466,ko:K03657,ko:K03684,ko:K03724 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03016,ko03036,ko03400 3.A.12 Bacteria 47QFS@768503,4NP3B@976,COG0349@1,COG0349@2 NA|NA|NA J 3'-5' exonuclease MAG.T22.3_00495 1239962.C943_02824 1.7e-260 904.8 Cytophagia nhaC ko:K03315 ko00000,ko02000 2.A.35 Bacteria 47KKY@768503,4NFQT@976,COG1757@1,COG1757@2 NA|NA|NA C TIGRFAM Na H antiporter NhaC MAG.T22.3_00496 1239962.C943_02825 1.5e-195 688.7 Cytophagia puuB ko:K09471 ko00330,ko01100,map00330,map01100 M00136 R07415 RC00062 ko00000,ko00001,ko00002,ko01000 Bacteria 47JUY@768503,4NEEY@976,COG0665@1,COG0665@2 NA|NA|NA E Glycine D-amino acid oxidase (deaminating) MAG.T22.3_00497 1239962.C943_02826 4.2e-83 313.9 Cytophagia Bacteria 47Q6B@768503,4NQIX@976,COG4539@1,COG4539@2 NA|NA|NA S Protein of unknown function (DUF962) MAG.T22.3_00498 1239962.C943_02827 7.1e-59 233.0 Cytophagia Bacteria 47QTI@768503,4NS6V@976,COG0662@1,COG0662@2 NA|NA|NA G mannose-6-phosphate isomerase MAG.T22.3_00499 1239962.C943_02828 0.0 1207.6 Bacteroidetes kefC ko:K03455 ko00000 2.A.37 Bacteria 4NGF6@976,COG0475@1,COG0475@2,COG1226@1,COG1226@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family MAG.T22.3_00500 1239962.C943_00231 0.0 1421.0 Cytophagia ko:K07001 ko00000 Bacteria 47KND@768503,4NF97@976,COG1752@1,COG1752@2 NA|NA|NA S Esterase of the alpha-beta hydrolase superfamily MAG.T22.3_00501 1239962.C943_00232 3.2e-92 344.4 Cytophagia Bacteria 2985A@1,2ZVB7@2,47QBF@768503,4NNTB@976 NA|NA|NA S Domain of unknown function (DUF4494) MAG.T22.3_00503 1239962.C943_00234 2.5e-104 384.8 Cytophagia ko:K06951 ko00000 Bacteria 47TAB@768503,4NIAC@976,COG2316@1,COG2316@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. MAG.T22.3_00504 1239962.C943_00235 1.8e-163 582.0 Cytophagia Bacteria 47YNK@768503,4PPHR@976,COG3829@1,COG3829@2 NA|NA|NA KT Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) MAG.T22.3_00505 1239962.C943_00236 2.1e-310 1070.8 Cytophagia cusB ko:K07798,ko:K15727 ko02020,map02020 ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1,8.A.1.2.1 Bacteria 47K97@768503,4NG8S@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.3_00506 1239962.C943_00237 5.2e-241 840.1 Cytophagia Bacteria 47NKF@768503,4NDXW@976,COG1538@1,COG1538@2 NA|NA|NA MU PFAM Outer membrane efflux protein MAG.T22.3_00507 1239962.C943_00238 0.0 2344.3 Bacteroidetes swrC ko:K03296,ko:K07787 ko02020,map02020 ko00000,ko00001,ko02000 2.A.6.1.4,2.A.6.2 Bacteria 4NDZG@976,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T22.3_00508 1239962.C943_00240 4.5e-166 590.5 Cytophagia ko:K21703,ko:K21711 ko00000,ko03000 Bacteria 47M6G@768503,4NGHS@976,COG0583@1,COG0583@2 NA|NA|NA K LysR family MAG.T22.3_00509 1239962.C943_00241 4.9e-58 230.7 Cytophagia Bacteria 2EEMG@1,338FD@2,47T2U@768503,4NW27@976 NA|NA|NA MAG.T22.3_00510 1239962.C943_00242 3e-165 587.8 Cytophagia sbtA ko:K07086 ko00000 Bacteria 47JXC@768503,4NIR4@976,COG3329@1,COG3329@2 NA|NA|NA S Na+-dependent bicarbonate transporter superfamily MAG.T22.3_00511 1048983.EL17_17100 4.2e-33 147.9 Cytophagia Bacteria 2DQQ3@1,33818@2,47VHM@768503,4NVCN@976 NA|NA|NA MAG.T22.3_00512 1239962.C943_00244 3.1e-156 557.8 Cytophagia Bacteria 47JX5@768503,4NE45@976,COG1028@1,COG1028@2 NA|NA|NA IQ Short-chain dehydrogenase reductase SDR MAG.T22.3_00513 1189612.A33Q_3167 1.3e-52 213.4 Cytophagia Bacteria 2DMZ1@1,32UGY@2,47RA8@768503,4NTGX@976 NA|NA|NA MAG.T22.3_00515 1239962.C943_00246 1.6e-249 868.2 Cytophagia ahcY GO:0000096,GO:0000097,GO:0000098,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0035375,GO:0035635,GO:0036094,GO:0036293,GO:0040007,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0070482,GO:0071268,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 Bacteria 47KGI@768503,4NEKE@976,COG0499@1,COG0499@2 NA|NA|NA H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine MAG.T22.3_00516 1239962.C943_00247 2.9e-139 501.1 Cytophagia birA 6.3.4.15 ko:K03523,ko:K03524 ko00780,ko01100,ko02010,map00780,map01100,map02010 M00581,M00582 R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 2.A.88.1,2.A.88.2 Bacteria 47MUP@768503,4NHCH@976,COG0340@1,COG0340@2 NA|NA|NA H PFAM Biotin lipoate A B protein ligase MAG.T22.3_00517 1239962.C943_00248 3.1e-59 234.2 Cytophagia rsfS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 ko:K00969,ko:K09710 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 47Q9C@768503,4NSKK@976,COG0799@1,COG0799@2 NA|NA|NA S Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation MAG.T22.3_00518 1239962.C943_00249 0.0 1323.1 Cytophagia ftsH ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 47KKF@768503,4NF0E@976,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins MAG.T22.3_00519 1239962.C943_00250 4.9e-150 537.0 Cytophagia lpxH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 iE2348C_1286.E2348C_0457 Bacteria 47JQJ@768503,4NEF1@976,COG2908@1,COG2908@2 NA|NA|NA S Calcineurin-like phosphoesterase MAG.T22.3_00520 1239962.C943_00251 4.5e-141 507.3 Cytophagia Bacteria 2CGN1@1,32S49@2,47R8D@768503,4NQPU@976 NA|NA|NA MAG.T22.3_00521 1239962.C943_00252 7.9e-73 279.6 Cytophagia slyD 5.2.1.8 ko:K01802,ko:K03774,ko:K03775 ko00000,ko01000,ko03110 Bacteria 47PG1@768503,4NM29@976,COG1047@1,COG1047@2 NA|NA|NA O Peptidyl-prolyl cis-trans isomerase MAG.T22.3_00522 1239962.C943_00253 3.1e-259 900.6 Cytophagia Bacteria 47JF9@768503,4NE89@976,COG2204@1,COG2204@2 NA|NA|NA T two component, sigma54 specific, transcriptional regulator, Fis family MAG.T22.3_00523 1239962.C943_00254 9.3e-221 772.7 Cytophagia Bacteria 47JZG@768503,4NEWF@976,COG5000@1,COG5000@2 NA|NA|NA T Histidine kinase MAG.T22.3_00524 866536.Belba_3690 1.2e-15 89.7 Cytophagia Bacteria 2E55B@1,32ZY9@2,47WUD@768503,4NVWQ@976 NA|NA|NA MAG.T22.3_00525 1239962.C943_00257 4.2e-158 563.9 Cytophagia lpxH_2 Bacteria 47MNV@768503,4NFD8@976,COG2908@1,COG2908@2 NA|NA|NA S Calcineurin-like phosphoesterase superfamily domain MAG.T22.3_00526 1239962.C943_00258 4e-196 690.6 Cytophagia Bacteria 47NVZ@768503,4PKSS@976,COG0707@1,COG0707@2 NA|NA|NA M Glycosyl transferase family 1 MAG.T22.3_00527 1239962.C943_00259 0.0 1856.3 Cytophagia 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 47M0W@768503,4NEUT@976,COG2334@1,COG2334@2 NA|NA|NA S glucosidase MAG.T22.3_00528 1239962.C943_00260 3.2e-104 384.4 Cytophagia rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 47KXS@768503,4NGVR@976,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids MAG.T22.3_00529 1239962.C943_00261 3.6e-86 324.3 Cytophagia ko:K09004 ko00000 Bacteria 47RQD@768503,4NVVJ@976,COG1416@1,COG1416@2 NA|NA|NA S DsrE/DsrF-like family MAG.T22.3_00530 1048983.EL17_06920 4.5e-13 82.8 Cytophagia Bacteria 28KQM@1,2ZA8D@2,47JWY@768503,4NH80@976 NA|NA|NA MAG.T22.3_00531 1239962.C943_00264 1.1e-178 632.5 Cytophagia Bacteria 47PJY@768503,4NJXA@976,COG3752@1,COG3752@2 NA|NA|NA S 3-oxo-5-alpha-steroid 4-dehydrogenase MAG.T22.3_00533 1239962.C943_00265 2e-155 555.1 Cytophagia folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 47K0S@768503,4NEJP@976,COG0190@1,COG0190@2 NA|NA|NA F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate MAG.T22.3_00534 237368.SCABRO_03886 5.2e-36 157.1 Planctomycetes Bacteria 2CCSR@1,2J1M5@203682,32RWC@2 NA|NA|NA S 23S rRNA-intervening sequence protein MAG.T22.3_00535 1239962.C943_00267 0.0 1151.3 Cytophagia lepA ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 47K4P@768503,4NEJ9@976,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner MAG.T22.3_00536 1239962.C943_00269 1.2e-84 319.3 Cytophagia Bacteria 2CGY7@1,2ZGS8@2,47Q8K@768503,4NREX@976 NA|NA|NA S Domain of unknown function (DUF4924) MAG.T22.3_00537 1239962.C943_00273 5.5e-99 367.1 Cytophagia Bacteria 2CDZ7@1,2Z8VK@2,47QSP@768503,4NIYY@976 NA|NA|NA MAG.T22.3_00538 1239962.C943_00275 1.8e-87 328.6 Cytophagia Bacteria 2B7X4@1,32143@2,47VBK@768503,4NNUI@976 NA|NA|NA MAG.T22.3_00539 1239962.C943_00276 0.0 1458.0 Cytophagia ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 47JJN@768503,4NDUK@976,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family MAG.T22.3_00540 1239962.C943_00278 6.8e-126 456.8 Cytophagia ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 47KMI@768503,4NFDW@976,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter MAG.T22.3_00541 1239962.C943_00280 0.0 1117.8 Cytophagia Bacteria 47M6V@768503,4NH87@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.3_00542 1239962.C943_00281 1.1e-218 765.8 Cytophagia ko:K02005 ko00000 Bacteria 47N10@768503,4NDUH@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.3_00543 1239962.C943_00283 1.7e-257 894.8 Cytophagia Bacteria 47JF9@768503,4NE89@976,COG2204@1,COG2204@2 NA|NA|NA T two component, sigma54 specific, transcriptional regulator, Fis family MAG.T22.3_00544 1239962.C943_00284 8.2e-241 839.3 Cytophagia Bacteria 47JZG@768503,4NEWF@976,COG5000@1,COG5000@2 NA|NA|NA T Histidine kinase MAG.T22.3_00545 1239962.C943_00286 0.0 1187.9 Cytophagia Bacteria 47MJ9@768503,4NEK7@976,COG0507@1,COG0507@2,COG1112@1,COG1112@2 NA|NA|NA L PFAM Type III restriction enzyme, res subunit MAG.T22.3_00547 1239962.C943_00288 1.2e-66 259.2 Cytophagia Bacteria 2EPSB@1,33HCU@2,47SU9@768503,4NYPB@976 NA|NA|NA MAG.T22.3_00548 1239962.C943_00289 3.8e-96 357.5 Cytophagia ppa 3.6.1.1 ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 47M21@768503,4NGBU@976,COG0221@1,COG0221@2 NA|NA|NA C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions MAG.T22.3_00549 1239962.C943_00290 1.6e-197 695.3 Cytophagia Bacteria 47QJA@768503,4NI5R@976,COG4251@1,COG4251@2 NA|NA|NA T GHKL domain MAG.T22.3_00550 1239962.C943_00291 0.0 1329.3 Cytophagia pgtB Bacteria 47NFW@768503,4NEJX@976,COG4191@1,COG4191@2 NA|NA|NA T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MAG.T22.3_00551 1239962.C943_00294 6.7e-81 306.6 Cytophagia Bacteria 47Q84@768503,4NP14@976,COG3437@1,COG3437@2 NA|NA|NA KT cheY-homologous receiver domain MAG.T22.3_00552 1239962.C943_00295 1.1e-215 755.7 Cytophagia ald 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 R00396 RC00008 ko00000,ko00001,ko01000 Bacteria 47J94@768503,4NE8F@976,COG0686@1,COG0686@2 NA|NA|NA E PFAM Alanine dehydrogenase PNT, C-terminal domain MAG.T22.3_00553 1239962.C943_00296 6.3e-73 280.0 Cytophagia yjeE 2.7.1.221 ko:K06925,ko:K07102 ko00520,ko01100,map00520,map01100 R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000,ko03016 Bacteria 47RDS@768503,4NS89@976,COG0802@1,COG0802@2 NA|NA|NA S PFAM Uncharacterised P-loop hydrolase UPF0079 MAG.T22.3_00554 1239962.C943_00297 1e-295 1021.9 Cytophagia porX ko:K03413 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko02022,ko02035 Bacteria 47KVF@768503,4NE72@976,COG2204@1,COG2204@2 NA|NA|NA T CheY-like receiver AAA-type ATPase and DNA-binding domains MAG.T22.3_00555 1239962.C943_00298 1.5e-225 788.5 Cytophagia ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 ko:K06885 ko00000 Bacteria 47JI5@768503,4NE1T@976,COG1078@1,COG1078@2 NA|NA|NA S SMART Metal-dependent phosphohydrolase, HD region MAG.T22.3_00556 1239962.C943_00299 2.6e-138 498.4 Cytophagia lpxD 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 47J9Z@768503,4NE5G@976,COG1044@1,COG1044@2 NA|NA|NA M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T22.3_00557 1239962.C943_00300 1.5e-266 924.9 Cytophagia fabZ GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 ko:K02372,ko:K02535,ko:K13599,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020 M00060,M00083,M00498,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022 Bacteria 47JFB@768503,4NEJ3@976,COG0764@1,COG0764@2,COG0774@1,COG0774@2 NA|NA|NA IM Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis MAG.T22.3_00558 1239962.C943_00301 1.3e-89 336.3 Cytophagia lpxA 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 47JJC@768503,4NEBA@976,COG1043@1,COG1043@2 NA|NA|NA M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T22.3_00559 1239962.C943_00302 3.2e-115 421.0 Cytophagia ccmA 3.6.3.41 ko:K01990,ko:K02193 ko02010,map02010 M00254,M00259 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.107 Bacteria 47PDC@768503,4NN9G@976,COG1131@1,COG1131@2 NA|NA|NA V PFAM ABC transporter MAG.T22.3_00560 1123057.P872_24965 1.2e-37 162.9 Cytophagia Bacteria 2DVMN@1,33WEK@2,47UX7@768503,4P35T@976 NA|NA|NA MAG.T22.3_00561 1239962.C943_00304 0.0 1459.5 Cytophagia mutS2 ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 47KJ6@768503,4NFE6@976,COG1193@1,COG1193@2 NA|NA|NA L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity MAG.T22.3_00562 1239962.C943_00306 4.2e-161 573.9 Cytophagia GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 Bacteria 47JXB@768503,4NE2N@976,COG1721@1,COG1721@2 NA|NA|NA S protein (some members contain a von Willebrand factor type A (vWA) domain) MAG.T22.3_00563 1239962.C943_00307 3.5e-147 527.7 Cytophagia Bacteria 2BPYJ@1,32ISF@2,47QN3@768503,4NRVJ@976 NA|NA|NA MAG.T22.3_00564 1239962.C943_00308 9.6e-197 692.6 Cytophagia batA ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 47JUP@768503,4NDUC@976,COG2304@1,COG2304@2 NA|NA|NA S PFAM von Willebrand factor type A MAG.T22.3_00565 1189612.A33Q_3182 4.7e-74 285.0 Bacteria Bacteria COG3391@1,COG3391@2 NA|NA|NA CO amine dehydrogenase activity MAG.T22.3_00567 1239962.C943_00309 2.5e-107 394.8 Cytophagia Bacteria 47S7H@768503,4NVAK@976,COG5523@1,COG5523@2 NA|NA|NA S integral membrane protein MAG.T22.3_00568 1239962.C943_00310 1.8e-179 635.2 Cytophagia ltd 4.2.1.45 ko:K01709 ko00520,map00520 R02426 RC00402 ko00000,ko00001,ko01000 Bacteria 47JUZ@768503,4NE3U@976,COG0451@1,COG0451@2 NA|NA|NA M PFAM NAD dependent epimerase dehydratase family MAG.T22.3_00569 1239962.C943_00311 6.8e-223 779.6 Cytophagia kbl GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 iECW_1372.ECW_m3896,iEKO11_1354.EKO11_0103,iPC815.YPO0059,iWFL_1372.ECW_m3896 Bacteria 47MGP@768503,4NFBU@976,COG0156@1,COG0156@2 NA|NA|NA H Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA MAG.T22.3_00570 1239962.C943_00312 8.5e-254 882.5 Cytophagia Bacteria 47MH5@768503,4NEV0@976,COG1228@1,COG1228@2 NA|NA|NA Q Amidohydrolase family MAG.T22.3_00571 1239962.C943_00313 0.0 1245.7 Cytophagia gnd 1.1.1.343,1.1.1.44,2.7.1.12,3.1.1.31 ko:K00033,ko:K00851,ko:K01057 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R01528,R01737,R02035,R10221 RC00001,RC00002,RC00017,RC00537,RC00539 ko00000,ko00001,ko00002,ko01000 Bacteria 47NDJ@768503,4NG05@976,COG0362@1,COG0362@2,COG3265@1,COG3265@2 NA|NA|NA G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH MAG.T22.3_00572 1239962.C943_00314 5.2e-265 919.8 Cytophagia ko:K07182 ko00000 Bacteria 47NMX@768503,4NDZ8@976,COG2905@1,COG2905@2 NA|NA|NA T signal-transduction protein containing cAMP-binding and CBS domains MAG.T22.3_00573 1239962.C943_00315 0.0 1550.4 Cytophagia nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.1.1.31,3.5.99.6 ko:K01057,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 47KPX@768503,4NDUN@976,COG0363@1,COG0363@2 NA|NA|NA G Glucosamine-6-phosphate isomerase MAG.T22.3_00574 1239962.C943_00316 3.2e-161 574.3 Cytophagia 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 47MF1@768503,4NJ71@976,COG1940@1,COG1940@2 NA|NA|NA GK PFAM ROK family MAG.T22.3_00575 1239962.C943_00317 2.6e-258 897.5 Cytophagia cbs GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00035,M00338 R00891,R00897,R01290,R03601,R04859,R04942 RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 47K1B@768503,4NDZ9@976,COG0031@1,COG0031@2,COG3620@1,COG3620@2 NA|NA|NA E Cystathionine beta-synthase MAG.T22.3_00576 1239962.C943_00318 0.0 1808.9 Cytophagia Bacteria 47JRP@768503,4NFP6@976,COG2010@1,COG2010@2 NA|NA|NA C Protein of unknown function (DUF1549) MAG.T22.3_00577 1239962.C943_00319 5.3e-297 1026.2 Cytophagia Bacteria 47K11@768503,4NGVK@976,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) MAG.T22.3_00578 1239962.C943_00320 1.7e-220 771.9 Bacteroidetes Bacteria 4NFES@976,COG4886@1,COG4886@2 NA|NA|NA S PFAM Planctomycete cytochrome C MAG.T22.3_00579 1239962.C943_00327 4.8e-49 200.7 Cytophagia spxA 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 47R1A@768503,4NSJ5@976,COG1393@1,COG1393@2 NA|NA|NA P Belongs to the ArsC family MAG.T22.3_00580 1239962.C943_00328 2.2e-268 931.0 Bacteroidetes ko:K06921 ko00000 Bacteria 4NGWE@976,COG1672@1,COG1672@2 NA|NA|NA S PFAM Archaeal ATPase MAG.T22.3_00581 1239962.C943_00329 7.2e-237 826.2 Cytophagia hemL GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 iSB619.SA_RS08395,iUMNK88_1353.UMNK88_158 Bacteria 47KB8@768503,4NDXG@976,COG0001@1,COG0001@2 NA|NA|NA H PFAM Aminotransferase class-III MAG.T22.3_00582 1239962.C943_00330 1.7e-304 1051.2 Cytophagia ko:K01999 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 47NJW@768503,4PKN8@976,COG0683@1,COG0683@2 NA|NA|NA E PFAM Receptor family ligand binding region MAG.T22.3_00583 1239962.C943_00332 9.1e-74 282.7 Cytophagia Bacteria 47QIH@768503,4NQAJ@976,COG4430@1,COG4430@2 NA|NA|NA S Bacteriocin-protection, YdeI or OmpD-Associated MAG.T22.3_00586 1123057.P872_05935 5.9e-10 71.6 Cytophagia Bacteria 296Q2@1,2ZTZ7@2,47WJW@768503,4P7KZ@976 NA|NA|NA MAG.T22.3_00587 1239962.C943_00335 2e-121 441.8 Cytophagia bcrA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 47PI7@768503,4NDV7@976,COG1131@1,COG1131@2 NA|NA|NA V ABC-type multidrug transport system ATPase component MAG.T22.3_00588 1239962.C943_00336 1.7e-271 941.4 Cytophagia Bacteria 28ID4@1,2Z8FC@2,47NAT@768503,4NFYZ@976 NA|NA|NA S Psort location CytoplasmicMembrane, score 10.00 MAG.T22.3_00589 1239962.C943_00337 2.3e-128 464.9 Cytophagia yfkO Bacteria 47Q2S@768503,4NEA5@976,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase family MAG.T22.3_00590 1239962.C943_00338 3.6e-241 840.5 Cytophagia ycaJ ko:K07478 ko00000 Bacteria 47JM9@768503,4NEV8@976,COG2256@1,COG2256@2 NA|NA|NA L PFAM MgsA AAA ATPase C terminal MAG.T22.3_00591 1239962.C943_00339 7.3e-248 862.8 Cytophagia VV3080 ko:K14445 ko00000,ko02000 2.A.47.1 Bacteria 47NGV@768503,4NFDK@976,COG0471@1,COG0471@2 NA|NA|NA P Sodium:sulfate symporter transmembrane region MAG.T22.3_00592 1239962.C943_00340 2.8e-144 518.1 Cytophagia lolI 5.3.99.11 ko:K06606 ko00562,ko01120,map00562,map01120 R09952 RC01513 ko00000,ko00001,ko01000 Bacteria 47NHQ@768503,4NEUS@976,COG1082@1,COG1082@2 NA|NA|NA G PFAM Xylose isomerase MAG.T22.3_00593 1239962.C943_00342 8e-123 446.4 Cytophagia Bacteria 2E4RS@1,32ZKA@2,47RDU@768503,4NVN5@976 NA|NA|NA MAG.T22.3_00594 1239962.C943_00343 0.0 1793.9 Cytophagia Bacteria 47K68@768503,4NF4B@976,COG1629@1,COG4771@2 NA|NA|NA P PFAM TonB-dependent Receptor Plug MAG.T22.3_00595 1239962.C943_00344 3.4e-211 740.7 Cytophagia Bacteria 28I8D@1,2Z8B7@2,47NIB@768503,4NM23@976 NA|NA|NA S Domain of unknown function (DUF4249) MAG.T22.3_00596 1239962.C943_00345 8.6e-207 726.1 Cytophagia Bacteria 28I8D@1,2Z8B7@2,47NIB@768503,4NM23@976 NA|NA|NA S Domain of unknown function (DUF4249) MAG.T22.3_00597 1239962.C943_00346 9.4e-297 1025.4 Bacteroidetes Bacteria 4NXND@976,COG2373@1,COG2373@2 NA|NA|NA S Large extracellular alpha-helical protein MAG.T22.3_00598 1239962.C943_00347 0.0 1673.3 Cytophagia Bacteria 47MS3@768503,4NHQ3@976,COG1520@1,COG1520@2 NA|NA|NA S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane MAG.T22.3_00599 1239962.C943_00348 1.5e-169 602.1 Cytophagia mdh 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 Bacteria 47MD1@768503,4NEJ7@976,COG0039@1,COG0039@2 NA|NA|NA C Catalyzes the reversible oxidation of malate to oxaloacetate MAG.T22.3_00600 1239962.C943_00350 5.1e-90 337.0 Cytophagia ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 Bacteria 47QJZ@768503,4NQ89@976,COG0664@1,COG0664@2 NA|NA|NA T PFAM Cyclic nucleotide-binding domain MAG.T22.3_00601 1239962.C943_00351 8.3e-246 855.9 Cytophagia tilS 6.3.4.19 ko:K04075 R09597 RC02633,RC02634 ko00000,ko01000,ko03016 Bacteria 47M2U@768503,4NEJS@976,COG0037@1,COG0037@2 NA|NA|NA D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine MAG.T22.3_00602 1239962.C943_00352 2.5e-276 957.6 Cytophagia lptD Bacteria 47KAE@768503,4NDU3@976,COG1452@1,COG1452@2 NA|NA|NA M OstA-like protein MAG.T22.3_00603 1239962.C943_00353 3e-125 454.5 Cytophagia Bacteria 2AEI8@1,331SH@2,47S6K@768503,4NWWM@976 NA|NA|NA MAG.T22.3_00604 1239962.C943_00354 7.1e-178 629.8 Cytophagia yfiO ko:K05807,ko:K08309 ko00000,ko01000,ko01011,ko02000 1.B.33.1 GH23 Bacteria 47MWE@768503,4NJ5A@976,COG4105@1,COG4105@2 NA|NA|NA S TIGRFAM Outer membrane assembly lipoprotein YfiO MAG.T22.3_00605 1239962.C943_00355 4.5e-49 200.3 Cytophagia rpoZ Bacteria 2CT4B@1,32SSJ@2,47RC2@768503,4NQ76@976 NA|NA|NA K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits MAG.T22.3_00606 1239962.C943_00356 2.2e-213 748.0 Cytophagia coaB 4.1.1.36,6.3.2.5 ko:K13038,ko:K21977 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 47MHR@768503,4NE46@976,COG0452@1,COG0452@2 NA|NA|NA H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine MAG.T22.3_00607 1239962.C943_00357 8.9e-167 592.8 Cytophagia Bacteria 28HA8@1,2Z7MQ@2,47N7V@768503,4NEJD@976 NA|NA|NA S Domain of unknown function (DUF4835) MAG.T22.3_00608 1239962.C943_00358 4.8e-143 513.8 Cytophagia yeeZ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 Bacteria 47PBQ@768503,4NMWC@976,COG0451@1,COG0451@2 NA|NA|NA GM epimerase MAG.T22.3_00610 1239962.C943_00360 4.1e-110 404.1 Cytophagia Bacteria 47PA0@768503,4NMV7@976,COG3000@1,COG3000@2 NA|NA|NA I Fatty acid hydroxylase MAG.T22.3_00611 1239962.C943_00361 3.6e-213 747.3 Cytophagia bshA GO:0003674,GO:0003824,GO:0016740,GO:0016757 ko:K00754 ko00000,ko01000 GT4 Bacteria 47JT9@768503,4NFPA@976,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferases group 1 MAG.T22.3_00612 1239962.C943_00362 0.0 1921.4 Cytophagia nagA 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 47K15@768503,4NET8@976,COG1472@1,COG1472@2,COG1680@1,COG1680@2 NA|NA|NA G Glycosyl hydrolase family 3 N terminal domain MAG.T22.3_00613 1239962.C943_00363 9.5e-52 209.5 Cytophagia Bacteria 2E1YR@1,32X7B@2,47R5A@768503,4NUBX@976 NA|NA|NA MAG.T22.3_00614 1239962.C943_00364 0.0 1204.1 Cytophagia mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 47KZU@768503,4NDWJ@976,COG0323@1,COG0323@2 NA|NA|NA L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex MAG.T22.3_00615 866536.Belba_1612 1e-110 406.4 Cytophagia 3.4.21.105 ko:K09650 ko00000,ko01000,ko01002,ko03029 Bacteria 47PBZ@768503,4NIYR@976,COG0705@1,COG0705@2 NA|NA|NA S PFAM Rhomboid family MAG.T22.3_00616 1239962.C943_00366 1.3e-157 562.4 Cytophagia Bacteria 47JAM@768503,4NGVJ@976,COG0705@1,COG0705@2 NA|NA|NA S PFAM Rhomboid family MAG.T22.3_00617 1239962.C943_00367 0.0 1672.1 Cytophagia Bacteria 47YJ8@768503,4PM9F@976,COG1629@1,COG1629@2 NA|NA|NA P TonB-dependent Receptor Plug Domain MAG.T22.3_00618 1239962.C943_00368 3e-197 694.5 Cytophagia rlmN 2.1.1.192 ko:K06941 ko00000,ko01000,ko03009 Bacteria 47KHN@768503,4NFH5@976,COG0820@1,COG0820@2 NA|NA|NA J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs MAG.T22.3_00619 1239962.C943_00369 5.4e-175 620.2 Cytophagia Bacteria 47JT7@768503,4NG1K@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T22.3_00620 1189612.A33Q_1499 2.1e-28 132.9 Cytophagia Bacteria 2BZ7F@1,33YY2@2,47VAY@768503,4P4AA@976 NA|NA|NA MAG.T22.3_00621 866536.Belba_0620 4e-19 102.1 Cytophagia Bacteria 2F3QY@1,33WHP@2,47UZ9@768503,4P2ZN@976 NA|NA|NA MAG.T22.3_00624 1239962.C943_00371 4.7e-218 763.5 Cytophagia Bacteria 47JWZ@768503,4NHPE@976,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase family MAG.T22.3_00625 1416760.AYMS01000059_gene1285 8.7e-45 186.4 Myroides Bacteria 1I84R@117743,47HXH@76831,4NKRD@976,COG4221@1,COG4221@2 NA|NA|NA S Enoyl-(Acyl carrier protein) reductase MAG.T22.3_00626 762903.Pedsa_1880 6.9e-37 159.8 Bacteria ko:K09946 ko00000 Bacteria COG3422@1,COG3422@2 NA|NA|NA S double-strand break repair MAG.T22.3_00627 743722.Sph21_4934 1.4e-34 152.9 Sphingobacteriia 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1IXTT@117747,4NT8K@976,COG2019@1,COG2019@2 NA|NA|NA F AAA domain MAG.T22.3_00628 871963.Desdi_0818 9.3e-153 547.0 Clostridia 2.6.1.98 ko:K13017 ko00520,map00520 R10141 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 1UMTT@1239,25GQK@186801,COG1848@1,COG1848@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase MAG.T22.3_00629 504487.JCM19302_971 1.7e-42 178.7 Flavobacteriia rplV ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1I54Z@117743,4NSWB@976,COG4933@1,COG4933@2 NA|NA|NA S ASCH MAG.T22.3_00630 865861.AZSU01000003_gene1806 6.2e-19 102.1 Clostridiaceae nudF 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 iHN637.CLJU_RS05505,iSB619.SA_RS07540,iYO844.BSU23610 Bacteria 1V6F5@1239,24JFS@186801,36ITW@31979,COG0494@1,COG0494@2 NA|NA|NA L nudix family MAG.T22.3_00631 1174528.JH992888_gene269 1.6e-21 110.2 Cyanobacteria Bacteria 1GFW5@1117,2EK29@1,33DSQ@2 NA|NA|NA MAG.T22.3_00632 1120966.AUBU01000022_gene2994 7.5e-20 102.8 Cytophagia Bacteria 47WTT@768503,4NV20@976,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins MAG.T22.3_00633 1239962.C943_01267 1.9e-68 265.0 Cytophagia Bacteria 47R94@768503,4NNY1@976,COG3832@1,COG3832@2 NA|NA|NA S Pfam Activator of Hsp90 ATPase homolog 1-like protein MAG.T22.3_00635 1239962.C943_01266 3.5e-55 220.7 Cytophagia rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47QDB@768503,4NNKU@976,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit MAG.T22.3_00636 1239962.C943_01265 5.6e-26 122.9 Cytophagia rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02916 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47RYG@768503,4NUVR@976,COG0291@1,COG0291@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL35 family MAG.T22.3_00637 1239962.C943_01264 2.4e-98 364.8 Cytophagia infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 47PC6@768503,4NIZ5@976,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins MAG.T22.3_00638 1239962.C943_01263 5.1e-82 310.5 Cytophagia cspC ko:K03704 ko00000,ko03000 Bacteria 47QKE@768503,4NNNH@976,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein domain MAG.T22.3_00639 1239962.C943_01262 2.3e-196 691.4 Bacteroidetes xdhC Bacteria 4NG02@976,COG1975@1,COG1975@2 NA|NA|NA O maturation factor XdhC CoxF family MAG.T22.3_00640 1239962.C943_01261 8.1e-79 300.1 Cytophagia pucB 1.1.1.328,1.17.1.4,2.7.7.76 ko:K00087,ko:K07141,ko:K07402,ko:K19190 ko00230,ko00760,ko00790,ko01100,ko01120,map00230,map00760,map00790,map01100,map01120 M00546 R01768,R02103,R10131,R10132,R11582 RC00143,RC03053 ko00000,ko00001,ko00002,ko01000 Bacteria 47PUQ@768503,4NQNF@976,COG2068@1,COG2068@2 NA|NA|NA S MobA-like NTP transferase domain MAG.T22.3_00641 1239962.C943_01260 2.6e-109 401.4 Cytophagia Bacteria 47S4Q@768503,4NV5A@976,COG4636@1,COG4636@2 NA|NA|NA S Putative restriction endonuclease MAG.T22.3_00642 1239962.C943_01259 2.8e-202 711.1 Cytophagia 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 47KUY@768503,4NG58@976,COG1104@1,COG1104@2 NA|NA|NA E Cysteine desulfurase MAG.T22.3_00643 1239962.C943_01258 2.5e-61 241.1 Cytophagia hxlR Bacteria 47QMW@768503,4NQ5S@976,COG1733@1,COG1733@2 NA|NA|NA K transcriptional regulator MAG.T22.3_00644 1239962.C943_01257 9.6e-138 496.1 Cytophagia Bacteria 47K2N@768503,4NGII@976,COG0693@1,COG0693@2 NA|NA|NA C DJ-1/PfpI family MAG.T22.3_00645 1239962.C943_01256 1.2e-138 499.2 Cytophagia Bacteria 47KAT@768503,4NHQU@976,COG3137@1,COG3137@2 NA|NA|NA M Protein of unknown function, DUF481 MAG.T22.3_00646 1239962.C943_01255 3.4e-161 574.3 Cytophagia yneE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08994 ko00000,ko02000 1.A.46.2 Bacteria 47KN8@768503,4NGJ0@976,COG3781@1,COG3781@2 NA|NA|NA S Bestrophin, RFP-TM, chloride channel MAG.T22.3_00647 1239962.C943_01254 7.8e-106 389.8 Cytophagia 1.5.1.40 ko:K06988 ko00000,ko01000 Bacteria 47QJ7@768503,4NEC7@976,COG2085@1,COG2085@2 NA|NA|NA S Rossmann-like domain MAG.T22.3_00648 1239962.C943_01253 2.4e-114 418.3 Cytophagia Bacteria 47M6D@768503,4NEK1@976,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T22.3_00649 1239962.C943_01251 8.7e-54 216.1 Cytophagia Bacteria 2DXPG@1,345UP@2,47VTA@768503,4P5W4@976 NA|NA|NA MAG.T22.3_00650 1239962.C943_01250 0.0 1334.7 Cytophagia glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECIAI39_1322.ECIAI39_0637 Bacteria 47MT0@768503,4NFCC@976,COG0008@1,COG0008@2 NA|NA|NA J PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain MAG.T22.3_00651 1239962.C943_01248 0.0 1420.6 Cytophagia 1.3.99.16 ko:K07303 ko00000,ko01000 Bacteria 47KVI@768503,4NFFU@976,COG1529@1,COG1529@2 NA|NA|NA C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain MAG.T22.3_00652 1239962.C943_01247 8.1e-84 316.2 Cytophagia 1.3.99.16 ko:K07302,ko:K07303 ko00000,ko01000 Bacteria 47PGG@768503,4NM72@976,COG2080@1,COG2080@2 NA|NA|NA C Aerobic-type carbon monoxide dehydrogenase small subunit CoxS MAG.T22.3_00653 1239962.C943_01246 8.3e-143 513.1 Cytophagia Bacteria 2DT8X@1,32UUQ@2,47SF7@768503,4NSYW@976 NA|NA|NA MAG.T22.3_00654 1239962.C943_01245 0.0 1136.3 Bacteroidetes gspA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K02450 M00331 ko00000,ko00002,ko02044 9.B.42 Bacteria 4NFKN@976,COG3409@1,COG3409@2 NA|NA|NA M N-acetylmuramidase MAG.T22.3_00655 1239962.C943_01244 1.9e-99 368.6 Bacteroidetes Bacteria 2ETBD@1,33KVB@2,4NSV4@976 NA|NA|NA S Protein of unknown function (DUF4230) MAG.T22.3_00656 1239962.C943_01243 0.0 1240.7 Bacteroidetes Bacteria 2F2KT@1,33VHI@2,4P2PT@976 NA|NA|NA MAG.T22.3_00657 1239962.C943_01242 0.0 1499.2 Cytophagia choD 1.1.3.6 ko:K03333 ko00984,ko01120,map00984,map01120 R01459 RC00146 ko00000,ko00001,ko01000 Bacteria 47RDM@768503,4NIU5@976,COG2303@1,COG2303@2 NA|NA|NA E GMC oxidoreductase MAG.T22.3_00658 1239962.C943_01241 4e-309 1066.6 Bacteroidetes Bacteria 4NHXB@976,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase MAG.T22.3_00659 1239962.C943_01240 5.2e-230 803.5 Bacteria Bacteria COG1752@1,COG1752@2 NA|NA|NA M Esterase of the alpha-beta hydrolase superfamily MAG.T22.3_00661 1239962.C943_01238 5.5e-49 200.3 Bacteroidetes ko:K07001 ko00000 Bacteria 4P64V@976,COG1752@1,COG1752@2 NA|NA|NA S Esterase of the alpha-beta hydrolase superfamily MAG.T22.3_00662 1239962.C943_01237 2e-83 315.1 Bacteroidetes Bacteria 2D13Y@1,32T9U@2,4P2IF@976 NA|NA|NA MAG.T22.3_00663 1239962.C943_01236 2e-171 608.2 Bacteria Bacteria COG4689@1,COG4689@2 NA|NA|NA Q acetoacetate decarboxylase activity MAG.T22.3_00664 1239962.C943_01235 1.3e-190 672.2 Bacteria 1.1.3.6 ko:K03333 ko00984,ko01120,map00984,map01120 R01459 RC00146 ko00000,ko00001,ko01000 Bacteria COG4757@1,COG4757@2 NA|NA|NA S Serine aminopeptidase, S33 MAG.T22.3_00666 1239962.C943_01232 3.8e-215 753.8 Cytophagia Bacteria 47JDD@768503,4NEC6@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha beta domain MAG.T22.3_00667 1239962.C943_01231 4.9e-85 320.5 Cytophagia Bacteria 47Q9F@768503,4PKP4@976,COG4319@1,COG4319@2 NA|NA|NA S Protein of unknown function (DUF2911) MAG.T22.3_00668 1239962.C943_01230 0.0 1515.0 Cytophagia hrpB 3.6.4.13 ko:K03579 ko00000,ko01000 Bacteria 47KRZ@768503,4NFJ7@976,COG1643@1,COG1643@2 NA|NA|NA L DEAD DEAH box helicase MAG.T22.3_00669 1239962.C943_01229 2.2e-139 501.9 Cytophagia Bacteria 47KEU@768503,4NEMN@976,COG0451@1,COG0451@2 NA|NA|NA GM NmrA-like family MAG.T22.3_00670 1239962.C943_01228 1.7e-132 478.8 Cytophagia ko:K07124 ko00000 Bacteria 47PBG@768503,4NKNE@976,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T22.3_00671 1239962.C943_01227 1.3e-111 409.1 Cytophagia Bacteria 28PET@1,2ZC69@2,47PCV@768503,4NMTJ@976 NA|NA|NA MAG.T22.3_00672 1239962.C943_01225 5.3e-114 417.2 Cytophagia Bacteria 28ZCA@1,2ZM41@2,47PNS@768503,4NMWJ@976 NA|NA|NA MAG.T22.3_00673 1239962.C943_01224 0.0 1249.2 Cytophagia ko:K06978 ko00000 Bacteria 47JKV@768503,4NFFB@976,COG2936@1,COG2936@2 NA|NA|NA S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain MAG.T22.3_00674 1239962.C943_01223 0.0 1654.0 Cytophagia parC GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 47JQZ@768503,4NERI@976,COG0188@1,COG0188@2 NA|NA|NA L Belongs to the type II topoisomerase GyrA ParC subunit family MAG.T22.3_00675 1239962.C943_01222 0.0 1233.0 Cytophagia parE 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 47JS9@768503,4NF18@976,COG0187@1,COG0187@2 NA|NA|NA L Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit MAG.T22.3_00676 1239962.C943_01221 1.1e-75 289.3 Cytophagia Bacteria 2AIV5@1,319CC@2,47QJ1@768503,4NRB1@976 NA|NA|NA MAG.T22.3_00677 1239962.C943_01220 2.4e-226 791.2 Cytophagia Bacteria 47KXY@768503,4NFWX@976,COG3000@1,COG3000@2 NA|NA|NA I PFAM Fatty acid hydroxylase MAG.T22.3_00678 1239962.C943_01219 3.8e-56 224.2 Cytophagia Bacteria 2C5P8@1,32U6D@2,47R86@768503,4NSY7@976 NA|NA|NA MAG.T22.3_00679 1239962.C943_01218 4.2e-41 173.7 Cytophagia Bacteria 2C4KB@1,32YM4@2,47RBT@768503,4NUZU@976 NA|NA|NA MAG.T22.3_00680 1239962.C943_01217 5.9e-177 626.7 Cytophagia GO:0000166,GO:0003674,GO:0003824,GO:0004033,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070402,GO:0097159,GO:1901265,GO:1901363 1.1.1.2 ko:K00002 ko00010,ko00040,ko00561,ko00930,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00561,map00930,map01100,map01110,map01120,map01130,map01220 M00014 R00746,R01041,R01481,R05231 RC00087,RC00088,RC00099,RC00108 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47NSB@768503,4NFTA@976,COG0656@1,COG0656@2 NA|NA|NA S PFAM Aldo keto reductase family MAG.T22.3_00681 1239962.C943_01215 4e-39 166.8 Cytophagia ypeB 2.7.7.7 ko:K02342,ko:K09954,ko:K10857 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 47RWJ@768503,4NUSP@976,COG3530@1,COG3530@2 NA|NA|NA S Putative quorum-sensing-regulated virulence factor MAG.T22.3_00682 1239962.C943_01214 2.1e-201 708.4 Cytophagia ko:K14645 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 47MBD@768503,4NI53@976,COG1404@1,COG1404@2 NA|NA|NA O Peptidase S8 MAG.T22.3_00683 1239962.C943_01213 0.0 1311.6 Cytophagia thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 47MA2@768503,4NEFT@976,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) MAG.T22.3_00684 1189612.A33Q_0853 3.4e-52 211.5 Cytophagia Bacteria 2AFVR@1,315YE@2,47SSJ@768503,4PK8B@976 NA|NA|NA MAG.T22.3_00685 1239962.C943_01212 0.0 1635.9 Cytophagia Bacteria 47MA1@768503,4NDYT@976,COG4775@1,COG4775@2 NA|NA|NA M CarboxypepD_reg-like domain MAG.T22.3_00686 1239962.C943_01211 5e-226 790.0 Cytophagia lhgO 1.1.99.2 ko:K00109,ko:K15736 ko00650,map00650 R03534 RC00031 ko00000,ko00001,ko01000 Bacteria 47JS1@768503,4NE0B@976,COG0579@1,COG0579@2 NA|NA|NA S PFAM FAD dependent oxidoreductase MAG.T22.3_00688 1239962.C943_01210 0.0 1257.3 Cytophagia 3.5.1.105 ko:K03478 ko00000,ko01000 Bacteria 47JKN@768503,4NEVS@976,COG1680@1,COG1680@2,COG3394@1,COG3394@2 NA|NA|NA V Beta-lactamase class C and other penicillin binding MAG.T22.3_00689 1239962.C943_01208 3.5e-61 240.7 Bacteria rnk ko:K03624,ko:K06140 ko00000,ko03000,ko03021 Bacteria COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus MAG.T22.3_00690 1239962.C943_01206 2.8e-193 681.0 Cytophagia ko:K07019 ko00000 Bacteria 47JJP@768503,4NFGZ@976,COG0429@1,COG0429@2 NA|NA|NA S Alpha beta hydrolase MAG.T22.3_00691 1239962.C943_01205 9e-248 862.4 Cytophagia hipO ko:K01436 ko00000,ko01000,ko01002 Bacteria 47NGQ@768503,4NGBI@976,COG1473@1,COG1473@2 NA|NA|NA S Peptidase dimerisation domain MAG.T22.3_00692 1239962.C943_01204 5.5e-101 373.6 Cytophagia Bacteria 2CJWV@1,2ZBKR@2,47PBB@768503,4NMFQ@976 NA|NA|NA MAG.T22.3_00693 1239962.C943_01203 1.3e-100 372.5 Cytophagia ko:K09931 ko00000 Bacteria 47PF2@768503,4NM7F@976,COG3222@1,COG3222@2 NA|NA|NA S protein conserved in bacteria MAG.T22.3_00694 1239962.C943_01201 2.8e-119 434.5 Cytophagia lsfA 1.11.1.15 ko:K03386,ko:K03665 ko04214,map04214 ko00000,ko00001,ko01000,ko03009,ko04147 Bacteria 47KEE@768503,4NEZZ@976,COG0450@1,COG0450@2 NA|NA|NA O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MAG.T22.3_00695 1239962.C943_01200 1e-201 709.1 Cytophagia fabH 2.3.1.180,2.3.1.207 ko:K00648,ko:K16872 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 iIT341.HP0202 Bacteria 47MUI@768503,4NEZE@976,COG0332@1,COG0332@2 NA|NA|NA I PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal MAG.T22.3_00696 1239962.C943_01199 3.4e-74 284.3 Cytophagia phzF Bacteria 47JVW@768503,4NEWM@976,COG0384@1,COG0384@2 NA|NA|NA S phenazine biosynthesis protein PhzF family MAG.T22.3_00697 1239962.C943_01199 7.9e-52 209.5 Cytophagia phzF Bacteria 47JVW@768503,4NEWM@976,COG0384@1,COG0384@2 NA|NA|NA S phenazine biosynthesis protein PhzF family MAG.T22.3_00698 1239962.C943_01198 3.5e-172 610.9 Cytophagia ko:K14347 ko00000,ko02000,ko04147 2.A.93.1 Bacteria 47K7V@768503,4NEDA@976,COG0385@1,COG0385@2 NA|NA|NA S SBF-like CPA transporter family (DUF4137) MAG.T22.3_00699 1239962.C943_01197 2.8e-121 441.4 Cytophagia spoU 2.1.1.170,2.1.1.185 ko:K03218,ko:K03437,ko:K03501 ko00000,ko01000,ko03009,ko03016,ko03036 Bacteria 47NSP@768503,4NG1U@976,COG0566@1,COG0566@2 NA|NA|NA J PFAM SpoU rRNA Methylase family MAG.T22.3_00700 1239962.C943_01196 0.0 1520.0 Cytophagia ko:K07277 ko00000,ko02000,ko03029 1.B.33 Bacteria 47Y47@768503,4PKIK@976,COG0729@1,COG0729@2 NA|NA|NA M Outer membrane protein, OMP85 family MAG.T22.3_00701 1239962.C943_01195 5.2e-90 337.0 Cytophagia sodC 1.15.1.1 ko:K02674,ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000,ko02035,ko02044 Bacteria 47SBX@768503,4NX0Y@976,COG2032@1,COG2032@2 NA|NA|NA P superoxide dismutase activity MAG.T22.3_00702 1239962.C943_01194 1e-293 1015.4 Cytophagia lig GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 47NBD@768503,4NEKP@976,COG1793@1,COG1793@2 NA|NA|NA L PFAM ATP dependent DNA ligase MAG.T22.3_00703 1239962.C943_01193 0.0 1565.8 Cytophagia lhr ko:K03724 ko00000,ko01000,ko03400 Bacteria 47NAU@768503,4NGQ0@976,COG1201@1,COG1201@2 NA|NA|NA L DEAD DEAH box helicase MAG.T22.3_00704 1239962.C943_01192 1.8e-281 974.9 Cytophagia ladS ko:K20971 ko02025,map02025 ko00000,ko00001,ko01001,ko02022 Bacteria 47KZN@768503,4NI29@976,COG0457@1,COG0457@2,COG4251@1,COG4251@2 NA|NA|NA T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MAG.T22.3_00705 1239962.C943_01191 1.8e-246 858.2 Cytophagia trkH GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662 ko:K03498,ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 iECDH1ME8569_1439.ECDH1ME8569_1308,iPC815.YPO3762,iSFV_1184.SFV_3651 Bacteria 47JH5@768503,4NGMF@976,COG0168@1,COG0168@2 NA|NA|NA P Cation transport protein MAG.T22.3_00706 1239962.C943_01190 5.3e-248 863.2 Cytophagia trkA ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 47NY5@768503,4NE31@976,COG0569@1,COG0569@2 NA|NA|NA P TrkA-N domain MAG.T22.3_00707 1239962.C943_01189 7.9e-96 356.7 Cytophagia Bacteria 47QGU@768503,4NRB9@976,COG0457@1,COG0457@2 NA|NA|NA S TPR repeat MAG.T22.3_00708 1239962.C943_01188 6.3e-167 593.6 Cytophagia rmuC ko:K09760 ko00000 Bacteria 47MZK@768503,4PJCR@976,COG1322@1,COG1322@2 NA|NA|NA S RmuC family MAG.T22.3_00709 1239962.C943_01187 5.1e-193 680.2 Cytophagia 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 Bacteria 47PBT@768503,4PMBK@976,COG0596@1,COG0596@2 NA|NA|NA S Thioesterase domain MAG.T22.3_00710 1239962.C943_01186 5.2e-142 510.4 Bacteroidetes Bacteria 4NM2E@976,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 MAG.T22.3_00711 1239962.C943_01185 7.2e-163 579.7 Bacteroidetes Bacteria 4NM2E@976,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 MAG.T22.3_00712 1239962.C943_01184 2.8e-191 674.5 Bacteroidetes pglH GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006464,GO:0006486,GO:0006487,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0008610,GO:0008653,GO:0008921,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035250,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.4.1.187,2.4.1.292 ko:K05946,ko:K16701,ko:K17249 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 GT26,GT4 Bacteria 4NGDA@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein MAG.T22.3_00713 1239962.C943_01183 1.7e-151 542.0 Bacteria rgpEc ko:K12998 ko00000,ko01000,ko01003,ko01005 GT2 Bacteria COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase, family 2 MAG.T22.3_00714 1239962.C943_01182 5.2e-306 1056.2 Cytophagia 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 47KZQ@768503,4NF8C@976,COG0154@1,COG0154@2 NA|NA|NA J Amidase MAG.T22.3_00716 1239962.C943_01181 1.4e-306 1058.1 Cytophagia pgi GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 iEcSMS35_1347.EcSMS35_4486 Bacteria 47JID@768503,4NDV0@976,COG0166@1,COG0166@2 NA|NA|NA G Belongs to the GPI family MAG.T22.3_00717 1239962.C943_01180 7.5e-103 380.2 Bacteria Bacteria COG0810@1,COG0810@2 NA|NA|NA M energy transducer activity MAG.T22.3_00718 1239962.C943_01179 6.8e-237 826.2 Cytophagia fahA 3.7.1.2 ko:K01555 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47KTT@768503,4NGI0@976,COG0179@1,COG0179@2 NA|NA|NA Q fumarylacetoacetate (FAA) hydrolase MAG.T22.3_00719 1239962.C943_01176 0.0 1400.2 Cytophagia Bacteria 47JYA@768503,4NEPV@976,COG2010@1,COG2010@2 NA|NA|NA C Planctomycete cytochrome C MAG.T22.3_00720 1239962.C943_01175 1.7e-284 984.6 Cytophagia Bacteria 47KYW@768503,4NE73@976,COG4102@1,COG4102@2 NA|NA|NA S Protein of unknown function (DUF1501) MAG.T22.3_00721 1239962.C943_01174 0.0 1269.6 Cytophagia Bacteria 47K53@768503,4NG07@976,COG4886@1,COG4886@2 NA|NA|NA S Planctomycete cytochrome C MAG.T22.3_00722 1239962.C943_01173 1.6e-126 458.8 Cytophagia Bacteria 47MJI@768503,4NHQW@976,COG4821@1,COG4821@2 NA|NA|NA S SIS domain MAG.T22.3_00723 1239962.C943_01040 4.1e-140 504.6 Cytophagia Bacteria 47XEP@768503,4NWRQ@976,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein MAG.T22.3_00724 1239962.C943_02244 7.1e-118 430.3 Bacteria Bacteria COG2067@1,COG2067@2 NA|NA|NA I long-chain fatty acid transporting porin activity MAG.T22.3_00725 1239962.C943_02243 3.3e-212 744.2 Cytophagia Bacteria 47QHX@768503,4NHNW@976,COG4775@1,COG4775@2 NA|NA|NA M Surface antigen MAG.T22.3_00726 1239962.C943_02242 0.0 1324.7 Bacteroidetes BDS1 Bacteria 4NJE2@976,COG2015@1,COG2015@2 NA|NA|NA Q Alkyl sulfatase dimerisation MAG.T22.3_00727 1239962.C943_02241 1.6e-197 695.3 Cytophagia Bacteria 47XEP@768503,4NWRQ@976,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein MAG.T22.3_00728 1120968.AUBX01000012_gene2672 2.5e-30 139.0 Bacteroidetes Bacteria 28N4A@1,2ZB9T@2,4NS50@976 NA|NA|NA S Domain of unknown function (DUF4136) MAG.T22.3_00729 1239962.C943_02239 2.1e-103 381.7 Bacteria lpxQ ko:K12980 ko00000,ko01005 Bacteria COG3637@1,COG3637@2 NA|NA|NA M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety MAG.T22.3_00730 1239962.C943_02238 2e-61 241.9 Cytophagia Bacteria 2CWBN@1,32SZD@2,47VSE@768503,4NU6S@976 NA|NA|NA MAG.T22.3_00731 1239962.C943_02237 1.8e-198 698.4 Cytophagia Bacteria 47KU9@768503,4NFR2@976,COG1262@1,COG1262@2 NA|NA|NA S Sulfatase-modifying factor enzyme 1 MAG.T22.3_00732 1239962.C943_02236 1.1e-220 772.3 Cytophagia Bacteria 47QHX@768503,4NHNW@976,COG4775@1,COG4775@2 NA|NA|NA M Surface antigen MAG.T22.3_00733 1239962.C943_02235 1.2e-37 164.5 Bacteroidetes Bacteria 2C7TI@1,2Z9KQ@2,4NJ91@976 NA|NA|NA MAG.T22.3_00734 1239962.C943_02232 1.2e-118 432.6 Bacteroidetes Bacteria 4NPSR@976,COG3900@1,COG3900@2 NA|NA|NA S periplasmic protein (DUF2092) MAG.T22.3_00735 1239962.C943_02229 4.1e-305 1053.1 Cytophagia amyY GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 R02108,R02112,R11262 ko00000,ko00001,ko01000 GH13 iLJ478.TM1840 Bacteria 47MR6@768503,4NEXF@976,COG0366@1,COG0366@2 NA|NA|NA G PFAM Alpha amylase, catalytic MAG.T22.3_00736 1239962.C943_02228 6.3e-204 716.5 Cytophagia fbaA GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 47MC3@768503,4NF5C@976,COG0191@1,COG0191@2 NA|NA|NA G fructose-bisphosphate aldolase, class II, yeast E. coli subtype MAG.T22.3_00737 1239962.C943_02227 0.0 1872.1 Cytophagia treZ 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13 Bacteria 47JN0@768503,4PKT8@976,COG0296@1,COG0296@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family MAG.T22.3_00738 1239962.C943_02226 1.5e-170 605.5 Cytophagia ko:K21571 ko00000 Bacteria 28JY0@1,2Z9ND@2,47N1W@768503,4NIG7@976 NA|NA|NA S Outer membrane protein SusF_SusE MAG.T22.3_00739 1239962.C943_02225 6.8e-187 659.8 Cytophagia cytR ko:K02529,ko:K05499 ko00000,ko03000 Bacteria 47MGC@768503,4NDW6@976,COG1609@1,COG1609@2 NA|NA|NA K PFAM Periplasmic binding protein LacI transcriptional regulator MAG.T22.3_00740 1239962.C943_02223 0.0 1639.8 Cytophagia agl 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 GH31 Bacteria 47NQ6@768503,4NE1H@976,COG1501@1,COG1501@2 NA|NA|NA G Belongs to the glycosyl hydrolase 31 family MAG.T22.3_00741 1239962.C943_02222 7.6e-247 859.4 Cytophagia ko:K16211 ko00000,ko02000 2.A.2.6 Bacteria 47KS1@768503,4NE3F@976,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator MAG.T22.3_00742 1239962.C943_02221 1.6e-149 535.4 Cytophagia pht5 4.1.1.55 ko:K02051,ko:K04102 ko00624,ko01100,ko01120,map00624,map01100,map01120 M00188,M00623 R01635,R05375 RC00390 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16,3.A.1.17 Bacteria 47JG1@768503,4NETN@976,COG0715@1,COG0715@2 NA|NA|NA P ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components MAG.T22.3_00743 1239962.C943_02220 3.6e-205 721.5 Cytophagia Bacteria 47UB6@768503,4NI29@976,COG0457@1,COG0457@2,COG0642@1,COG2205@2 NA|NA|NA T Tetratricopeptide repeat MAG.T22.3_00744 1239962.C943_02219 8.8e-226 789.3 Cytophagia ko:K14645 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 47MBD@768503,4NI53@976,COG1404@1,COG1404@2 NA|NA|NA O Peptidase S8 MAG.T22.3_00745 1239962.C943_02218 3.4e-108 397.9 Cytophagia Bacteria 2C0SB@1,33XRP@2,47V76@768503,4P2YY@976 NA|NA|NA MAG.T22.3_00746 1239962.C943_02217 1.6e-171 608.6 Cytophagia rlmI 2.1.1.191 ko:K06969 ko00000,ko01000,ko03009 Bacteria 47MFA@768503,4NGJX@976,COG1092@1,COG1092@2 NA|NA|NA J S-adenosylmethionine-dependent methyltransferase MAG.T22.3_00747 1239962.C943_02216 2.1e-70 271.6 Cytophagia Bacteria 2DN0J@1,32UI3@2,47R55@768503,4NT4U@976 NA|NA|NA MAG.T22.3_00748 1123057.P872_10080 1e-43 183.0 Cytophagia Bacteria 2D0AC@1,32T87@2,47SEN@768503,4NSVN@976 NA|NA|NA MAG.T22.3_00749 1239962.C943_02213 2.7e-58 231.1 Cytophagia ko:K07023 ko00000 Bacteria 47R6T@768503,4PND1@976,COG4538@1,COG4538@2 NA|NA|NA S SnoaL-like domain MAG.T22.3_00751 1239962.C943_02212 2.5e-305 1053.9 Cytophagia ybiT GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 ko:K06158 ko00000,ko03012 Bacteria 47J97@768503,4NEHU@976,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter MAG.T22.3_00752 1239962.C943_02211 1.1e-248 865.5 Cytophagia putP ko:K03307,ko:K14387 ko04725,ko05231,map04725,map05231 ko00000,ko00001,ko02000 2.A.21,2.A.21.8 Bacteria 47JA4@768503,4NH7H@976,COG0591@1,COG0591@2 NA|NA|NA E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family MAG.T22.3_00753 1239962.C943_02210 1e-218 765.8 Cytophagia rlmI GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.191 ko:K06969 ko00000,ko01000,ko03009 Bacteria 47M5H@768503,4NG9S@976,COG1092@1,COG1092@2 NA|NA|NA J SAM-dependent methyltransferase MAG.T22.3_00754 1239962.C943_02209 0.0 1996.1 Cytophagia ko:K08676 ko00000,ko01000,ko01002 Bacteria 47NFD@768503,4NGU2@976,COG0793@1,COG0793@2,COG4946@1,COG4946@2 NA|NA|NA M Tricorn protease homolog MAG.T22.3_00755 1239962.C943_02208 0.0 1453.3 Cytophagia bglX GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008422,GO:0009056,GO:0009057,GO:0009251,GO:0015926,GO:0016020,GO:0016052,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044042,GO:0044238,GO:0044464,GO:0071704,GO:0071944,GO:1901575 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 GH3 iECOK1_1307.ECOK1_2363,iECS88_1305.ECS88_2276,iSF_1195.SF2217,iSFxv_1172.SFxv_2448,iS_1188.S2346,iUMN146_1321.UM146_06125,iUTI89_1310.UTI89_C2406 Bacteria 47JBR@768503,4NE90@976,COG1472@1,COG1472@2 NA|NA|NA G Belongs to the glycosyl hydrolase 3 family MAG.T22.3_00756 1239962.C943_02207 1.3e-254 885.2 Cytophagia Bacteria 47P3I@768503,4NE34@976,COG5368@1,COG5368@2 NA|NA|NA S protein conserved in bacteria MAG.T22.3_00757 1239962.C943_02206 0.0 1302.3 Cytophagia Bacteria 47M1C@768503,4NE34@976,COG5368@1,COG5368@2 NA|NA|NA S protein conserved in bacteria MAG.T22.3_00758 1239962.C943_02205 1.4e-198 698.7 Cytophagia 3.2.1.8 ko:K01181 ko00000,ko01000 Bacteria 47YQS@768503,4PPR5@976,COG3507@1,COG3507@2 NA|NA|NA G Concanavalin A-like lectin/glucanases superfamily MAG.T22.3_00759 1239962.C943_02204 1.5e-291 1008.1 Cytophagia ko:K21572 ko00000,ko02000 8.A.46.1,8.A.46.3 Bacteria 47U8Q@768503,4NER5@976,COG0446@1,COG0446@2 NA|NA|NA S SusD family MAG.T22.3_00760 1239962.C943_02203 0.0 2217.6 Cytophagia Bacteria 47KYY@768503,4NDXS@976,COG1629@1,COG1629@2 NA|NA|NA P TonB-dependent receptor MAG.T22.3_00761 1239962.C943_02201 6.1e-186 656.8 Cytophagia Bacteria 47KZE@768503,4NH3M@976,COG3712@1,COG3712@2 NA|NA|NA PT PFAM FecR protein MAG.T22.3_00762 1239962.C943_02200 1.8e-97 362.1 Cytophagia ko:K03088 ko00000,ko03021 Bacteria 47KQJ@768503,4NKX6@976,COG1595@1,COG1595@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family MAG.T22.3_00763 1239962.C943_02199 1.5e-52 211.8 Cytophagia yqjZ 2.3.1.128,2.5.1.18 ko:K00799,ko:K03790 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000,ko03009 1.A.12.2.2,1.A.12.3.2 Bacteria 47RR3@768503,4NS8X@976,COG2329@1,COG2329@2 NA|NA|NA S involved in biosynthesis of extracellular polysaccharides MAG.T22.3_00764 1239962.C943_02198 1.5e-107 395.6 Cytophagia Bacteria 2C25Y@1,3399H@2,47SDB@768503,4NXDI@976 NA|NA|NA MAG.T22.3_00765 1239962.C943_02197 6.2e-109 400.2 Bacteria Bacteria COG0702@1,COG0702@2 NA|NA|NA GM epimerase MAG.T22.3_00766 1239962.C943_02196 0.0 1539.6 Cytophagia wzc GO:0000271,GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016301,GO:0016310,GO:0016462,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0036211,GO:0038083,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046377,GO:0046777,GO:0071704,GO:0071944,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 ko:K16692 ko00000,ko01000,ko01001 Bacteria 47JQC@768503,4NEXU@976,COG0489@1,COG0489@2,COG3206@1,COG3206@2 NA|NA|NA DM TIGRFAM capsular exopolysaccharide family MAG.T22.3_00767 1239962.C943_02195 9.2e-139 499.6 Bacteria wza ko:K01991 ko02026,map02026 ko00000,ko00001,ko02000 1.B.18 Bacteria COG1596@1,COG1596@2 NA|NA|NA M polysaccharide export MAG.T22.3_00768 1239962.C943_02194 5.2e-181 640.2 Cytophagia Bacteria 47PCK@768503,4NK5Y@976,COG0726@1,COG0726@2 NA|NA|NA G Polysaccharide deacetylase MAG.T22.3_00769 1239962.C943_02193 1.9e-188 665.2 Bacteroidetes Bacteria 2DBB7@1,2Z85R@2,4NJNG@976 NA|NA|NA MAG.T22.3_00771 1239962.C943_02189 2.2e-105 388.3 Cytophagia Bacteria 47PRX@768503,4NNYV@976,COG1434@1,COG1434@2 NA|NA|NA S PFAM DUF218 domain MAG.T22.3_00772 1239962.C943_02188 1.1e-150 539.3 Cytophagia dcsG 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 47KCY@768503,4NGQ4@976,COG0189@1,COG0189@2 NA|NA|NA HJ ligase activity MAG.T22.3_00773 1239962.C943_02187 3.6e-137 494.2 Cytophagia dpm1 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003 GT2 Bacteria 47JE4@768503,4NEHI@976,COG1216@1,COG1216@2 NA|NA|NA S PFAM Glycosyl transferase family 2 MAG.T22.3_00774 1239962.C943_02186 2.7e-195 688.0 Cytophagia lolE_1 ko:K09808 ko02010,map02010 M00255 ko00000,ko00001,ko00002,ko02000 3.A.1.125 Bacteria 47KVD@768503,4NFWZ@976,COG4591@1,COG4591@2 NA|NA|NA M ABC-type transport system involved in lipoprotein release permease component MAG.T22.3_00775 1239962.C943_02185 1.1e-223 782.3 Cytophagia Bacteria 47KTI@768503,4NEXD@976,COG3876@1,COG3876@2 NA|NA|NA S PFAM Uncharacterised conserved protein UCP016719 MAG.T22.3_00776 1239962.C943_02184 4.7e-88 330.5 Cytophagia Bacteria 2CDEV@1,2ZP0V@2,47WUU@768503,4P8Q6@976 NA|NA|NA MAG.T22.3_00777 1239962.C943_02183 6.1e-64 250.0 Cytophagia Bacteria 47VEQ@768503,4NQRI@976,COG3439@1,COG3439@2 NA|NA|NA S Domain of unknown function DUF302 MAG.T22.3_00779 1239962.C943_02181 1.9e-182 645.2 Cytophagia glxK 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 R08572 RC00002,RC00428 ko00000,ko00001,ko01000 Bacteria 47MW7@768503,4NFK8@976,COG1929@1,COG1929@2 NA|NA|NA G Belongs to the glycerate kinase type-1 family MAG.T22.3_00780 1239962.C943_02180 2.5e-242 844.3 Cytophagia alsT_2 ko:K03310 ko00000 2.A.25 Bacteria 47JCJ@768503,4NDX7@976,COG1115@1,COG1115@2 NA|NA|NA E PFAM Sodium alanine symporter family MAG.T22.3_00781 1239962.C943_02178 0.0 2506.1 Cytophagia 3.6.4.13 ko:K03578,ko:K03579 ko00000,ko01000 Bacteria 47KY5@768503,4NF2S@976,COG1112@1,COG1112@2,COG1643@1,COG1643@2 NA|NA|NA L Superfamily I DNA and RNA MAG.T22.3_00782 1239962.C943_02177 7.8e-146 523.1 Cytophagia Bacteria 47JGN@768503,4NEMK@976,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T22.3_00783 945713.IALB_1249 1.5e-45 189.1 Bacteria ko:K07491 ko00000 Bacteria COG1943@1,COG1943@2 NA|NA|NA L Transposase MAG.T22.3_00784 1239962.C943_02176 1.8e-262 911.4 Cytophagia rumA 2.1.1.190 ko:K03215 ko00000,ko01000,ko03009 Bacteria 47KB6@768503,4NFP1@976,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family MAG.T22.3_00785 1239962.C943_02175 4.8e-66 256.9 Cytophagia Bacteria 2BXI1@1,32R1C@2,47QU5@768503,4NR9I@976 NA|NA|NA MAG.T22.3_00786 1239962.C943_02174 2.1e-95 355.1 Bacteria ko:K03088 ko00000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation MAG.T22.3_00787 1239962.C943_02173 1.4e-190 672.2 Bacteroidetes Bacteria 4NSUQ@976,COG3712@1,COG3712@2 NA|NA|NA PT Pfam FecR protein MAG.T22.3_00788 1239962.C943_02172 0.0 2242.6 Cytophagia Bacteria 47Y4V@768503,4NDU8@976,COG1629@1,COG4771@2 NA|NA|NA P TonB dependent receptor MAG.T22.3_00789 1239962.C943_02171 7.2e-278 962.6 Cytophagia Bacteria 47Y4U@768503,4NEAX@976,COG4198@1,COG4198@2 NA|NA|NA S Starch-binding associating with outer membrane MAG.T22.3_00790 1239962.C943_02170 7.8e-174 616.3 Cytophagia Bacteria 47KRJ@768503,4NF3M@976,COG0684@1,COG0684@2 NA|NA|NA H Aldolase/RraA MAG.T22.3_00791 1239962.C943_02169 1.8e-250 871.3 Cytophagia 4.2.1.6 ko:K01684 ko00052,ko01100,ko01120,map00052,map01100,map01120 M00552 R03033 RC00543 ko00000,ko00001,ko00002,ko01000 Bacteria 47K75@768503,4NIIJ@976,COG4948@1,COG4948@2 NA|NA|NA M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAG.T22.3_00792 1239962.C943_02168 1.7e-251 874.8 Cytophagia 4.2.1.6 ko:K01684 ko00052,ko01100,ko01120,map00052,map01100,map01120 M00552 R03033 RC00543 ko00000,ko00001,ko00002,ko01000 Bacteria 47K75@768503,4NIIJ@976,COG4948@1,COG4948@2 NA|NA|NA M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAG.T22.3_00793 1239962.C943_02167 8e-179 632.9 Cytophagia Bacteria 47JU7@768503,4NF3M@976,COG0684@1,COG0684@2 NA|NA|NA H Aldolase/RraA MAG.T22.3_00794 1239962.C943_02166 9.6e-251 872.5 Cytophagia Bacteria 47NDY@768503,4NE9A@976,COG4948@1,COG4948@2 NA|NA|NA M Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAG.T22.3_00795 1239962.C943_02165 4.9e-188 663.7 Cytophagia yocS ko:K03453 ko00000 2.A.28 Bacteria 47JSH@768503,4NEIM@976,COG0385@1,COG0385@2 NA|NA|NA S PFAM Bile acid sodium symporter MAG.T22.3_00796 243275.TDE_2749 4.7e-31 140.6 Spirochaetes Bacteria 2J8NR@203691,COG4226@1,COG4226@2 NA|NA|NA S HicB family MAG.T22.3_00797 913865.DOT_3277 1.4e-16 92.0 Peptococcaceae hicA Bacteria 1VHPB@1239,24SMK@186801,266IG@186807,2E9T0@1,333Z2@2 NA|NA|NA S HicA toxin of bacterial toxin-antitoxin, MAG.T22.3_00798 1239962.C943_02164 1.2e-186 659.1 Cytophagia thiL 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 iYO844.BSU05900 Bacteria 47JR7@768503,4NDUT@976,COG0611@1,COG0611@2 NA|NA|NA H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 MAG.T22.3_00799 1121272.KB903254_gene6721 3.6e-23 115.5 Bacteria Bacteria 2E3IT@1,32XW0@2 NA|NA|NA MAG.T22.3_00800 1121011.AUCB01000049_gene3207 6.6e-131 473.8 Arenibacter ko:K07341 ko00000,ko02048 Bacteria 1HYIM@117743,23HK1@178469,4NEGN@976,COG3654@1,COG3654@2,COG3943@1,COG3943@2 NA|NA|NA S Virulence protein RhuM family MAG.T22.3_00801 1239962.C943_02160 3.2e-68 264.2 Cytophagia mce 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 Bacteria 47PQ6@768503,4NNGG@976,COG0346@1,COG0346@2 NA|NA|NA E PFAM Glyoxalase bleomycin resistance protein dioxygenase MAG.T22.3_00802 1239962.C943_02159 3.3e-55 220.7 Cytophagia sufA ko:K13628 ko00000,ko03016 Bacteria 47QAX@768503,4NQC8@976,COG0316@1,COG0316@2 NA|NA|NA S Belongs to the HesB IscA family MAG.T22.3_00803 1239962.C943_02158 5.5e-203 713.4 Cytophagia gcvT 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 Bacteria 47MN7@768503,4NF7S@976,COG0404@1,COG0404@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine MAG.T22.3_00804 1239962.C943_02157 1.1e-127 462.6 Cytophagia comB GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 ko:K05979 ko00680,ko01120,map00680,map01120 M00358 R05789 RC00428 ko00000,ko00001,ko00002,ko01000 Bacteria 47M1W@768503,4NG1A@976,COG2045@1,COG2045@2 NA|NA|NA H Belongs to the ComB family MAG.T22.3_00805 1239962.C943_02156 1.4e-167 595.5 Cytophagia prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iLJ478.TM1628,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665 Bacteria 47MGR@768503,4NEVF@976,COG0462@1,COG0462@2 NA|NA|NA EF Ribose-phosphate pyrophosphokinase MAG.T22.3_00806 1239962.C943_02155 1.7e-99 368.6 Cytophagia ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02897 ko03010,map03010 M00178 ko00000,ko00001,ko00002,ko03011 Bacteria 47NVP@768503,4NEN6@976,COG1825@1,COG1825@2 NA|NA|NA J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance MAG.T22.3_00807 1239962.C943_02154 3.9e-104 384.0 Cytophagia pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 47Q0M@768503,4NI7N@976,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis MAG.T22.3_00808 1120965.AUBV01000006_gene2159 9.1e-170 603.2 Bacteroidetes Bacteria 2E1XI@1,32X6H@2,4NSAN@976 NA|NA|NA MAG.T22.3_00811 1239962.C943_02150 3.1e-212 744.2 Cytophagia metZ GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.8 ko:K01739,ko:K01760,ko:K10764 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0391 Bacteria 47KC8@768503,4PKE6@976,COG0626@1,COG0626@2 NA|NA|NA E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide MAG.T22.3_00812 1239962.C943_02149 4.8e-219 766.9 Cytophagia ko:K13963 ko05146,map05146 ko00000,ko00001 Bacteria 47N0P@768503,4NG1G@976,COG4826@1,COG4826@2 NA|NA|NA O proteinase inhibitor I4 serpin MAG.T22.3_00814 1239962.C943_02147 5e-91 340.5 Cytophagia Bacteria 47RFJ@768503,4NKNI@976,COG4430@1,COG4430@2 NA|NA|NA S Bacteriocin-protection, YdeI or OmpD-Associated MAG.T22.3_00815 1239962.C943_02146 1.6e-70 271.9 Cytophagia Bacteria 2CHCP@1,32S5R@2,47RF4@768503,4NS9G@976 NA|NA|NA S Domain of unknown function (DU1801) MAG.T22.3_00817 1239962.C943_02142 7.7e-179 633.6 Bacteroidetes Bacteria 4NF6Y@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.3_00818 1239962.C943_02141 0.0 1841.2 Cytophagia czcA ko:K07239,ko:K07787 ko02020,map02020 ko00000,ko00001,ko02000 2.A.6.1,2.A.6.1.4 Bacteria 47JFH@768503,4P36A@976,COG3696@1,COG3696@2 NA|NA|NA P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T22.3_00819 1239962.C943_02140 6.3e-197 693.3 Bacteroidetes Bacteria 4NIE8@976,COG1538@1,COG1538@2 NA|NA|NA MU outer membrane efflux protein MAG.T22.3_00820 1239962.C943_02139 1.2e-152 545.8 Cytophagia elaC 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 47U32@768503,4NM16@976,COG1235@1,COG1235@2 NA|NA|NA S Beta-lactamase superfamily domain MAG.T22.3_00821 1239962.C943_02138 6.4e-69 266.5 Cytophagia Bacteria 2BWYK@1,32R5D@2,47UWC@768503,4NS4D@976 NA|NA|NA T PAS domain MAG.T22.3_00822 1239962.C943_03247 1.4e-114 419.1 Cytophagia asd 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1523 Bacteria 47JMK@768503,4NE4V@976,COG0136@1,COG0136@2 NA|NA|NA E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate MAG.T22.3_00823 1239962.C943_03246 2.1e-195 688.3 Cytophagia Bacteria 47KTZ@768503,4PKBS@976,COG2265@1,COG2265@2 NA|NA|NA J (SAM)-dependent MAG.T22.3_00825 1237149.C900_00677 4e-15 87.4 Bacteroidetes Bacteria 4NUJP@976,COG3668@1,COG3668@2 NA|NA|NA S ParE toxin of type II toxin-antitoxin system, parDE MAG.T22.3_00826 1305737.JAFX01000001_gene1343 7.4e-49 200.3 Bacteroidetes merR Bacteria 4NQCR@976,COG3620@1,COG3620@2 NA|NA|NA K transcriptional regulator MAG.T22.3_00827 1305737.JAFX01000001_gene1344 1.8e-26 124.8 Cytophagia Bacteria 2AE47@1,313XF@2,47WB2@768503,4NYMZ@976 NA|NA|NA S Domain of unknown function (DUF4160) MAG.T22.3_00828 1239962.C943_03245 8.7e-240 835.9 Cytophagia thrC GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025 Bacteria 47KUN@768503,4NEAA@976,COG0498@1,COG0498@2 NA|NA|NA E Threonine synthase MAG.T22.3_00829 1239962.C943_03243 4.3e-164 583.9 Cytophagia thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545,iSB619.SA_RS06620 Bacteria 47KGY@768503,4NE2M@976,COG0083@1,COG0083@2 NA|NA|NA E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate MAG.T22.3_00830 1239962.C943_03242 0.0 1551.2 Cytophagia thrA GO:0003674,GO:0003824,GO:0004072,GO:0004412,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009090,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_0002,iEcDH1_1363.EcDH1_3594,iSFV_1184.SFV_0001 Bacteria 47KEQ@768503,4NFGR@976,COG0460@1,COG0460@2,COG0527@1,COG0527@2 NA|NA|NA E TIGRFAM Aspartate kinase MAG.T22.3_00831 1239962.C943_03240 7e-69 266.5 Bacteroidetes ko:K03668,ko:K09914 ko00000 Bacteria 4NZHU@976,COG3187@1,COG3187@2 NA|NA|NA O META domain MAG.T22.3_00832 1239962.C943_03239 3.8e-105 387.5 Cytophagia Bacteria 47PXG@768503,4NRH5@976,COG4843@1,COG4843@2 NA|NA|NA S protein conserved in bacteria (DUF2179) MAG.T22.3_00833 1239962.C943_03238 2.6e-187 661.4 Cytophagia yeaN GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 ko:K03449 ko00000,ko02000 2.A.1.17 Bacteria 47TFV@768503,4NHIR@976,COG2807@1,COG2807@2 NA|NA|NA P Major Facilitator Superfamily MAG.T22.3_00834 1120965.AUBV01000008_gene2063 1.7e-187 661.8 Cytophagia GO:0003674,GO:0003824,GO:0006575,GO:0006577,GO:0006579,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0034641,GO:0036361,GO:0042219,GO:0044237,GO:0044248,GO:0044270,GO:0047580,GO:0047661,GO:0071704,GO:1901564,GO:1901565,GO:1901575 5.1.1.8 ko:K12658 ko00330,map00330 R03296 RC00479 ko00000,ko00001,ko01000 Bacteria 47KV9@768503,4NHJZ@976,COG3938@1,COG3938@2 NA|NA|NA E Belongs to the proline racemase family MAG.T22.3_00835 1239962.C943_03235 5.3e-270 936.4 Cytophagia aldH 1.2.1.26,1.2.1.4 ko:K13877,ko:K14519 ko00040,ko00053,ko00930,ko01100,ko01120,ko01220,map00040,map00053,map00930,map01100,map01120,map01220 R00264,R05099 RC00080 ko00000,ko00001,ko01000 Bacteria 47MQT@768503,4NEKG@976,COG1012@1,COG1012@2 NA|NA|NA C PFAM Aldehyde dehydrogenase MAG.T22.3_00836 1239962.C943_03234 6.5e-162 576.6 Cytophagia dapA2 3.5.4.22,4.3.3.7 ko:K01714,ko:K21062 ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R02280,R10147 RC00679,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 47MUZ@768503,4NF2Z@976,COG0329@1,COG0329@2 NA|NA|NA EM Belongs to the DapA family MAG.T22.3_00837 1239962.C943_03233 2.7e-155 554.7 Cytophagia mltR Bacteria 47PQJ@768503,4NGHV@976,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein MAG.T22.3_00838 1239962.C943_03232 6e-241 839.7 Cytophagia murF 6.3.2.10,6.3.2.13 ko:K01928,ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 47MCP@768503,4NDWD@976,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein MAG.T22.3_00839 1239962.C943_03231 0.0 1220.7 Cytophagia Bacteria 2DM9M@1,3296A@2,47Y3U@768503,4PMKJ@976 NA|NA|NA S Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MAG.T22.3_00840 1239962.C943_03230 1.5e-144 518.8 Cytophagia panB 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 Bacteria 47K8P@768503,4NDX4@976,COG0413@1,COG0413@2 NA|NA|NA H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate MAG.T22.3_00841 1239962.C943_03229 7.6e-75 286.6 Cytophagia pyrR GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 Bacteria 47QMM@768503,4NNRI@976,COG2065@1,COG2065@2 NA|NA|NA F Pyrimidine operon attenuation protein uracil phosphoribosyltransferase MAG.T22.3_00842 1120966.AUBU01000006_gene3492 8.8e-12 77.8 Bacteroidetes Bacteria 28M3Z@1,32ZEY@2,4NUZS@976 NA|NA|NA MAG.T22.3_00843 1239962.C943_03226 1.8e-240 838.2 Cytophagia lysC GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009090,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4,4.1.1.20 ko:K00928,ko:K12526 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00451,R00480 RC00002,RC00043,RC00299 ko00000,ko00001,ko00002,ko01000 iECED1_1282.ECED1_4739,iPC815.YPO3719 Bacteria 47KM0@768503,4NFWR@976,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family MAG.T22.3_00844 1239962.C943_03225 1.3e-84 318.9 Cytophagia ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1825,iSB619.SA_RS08940,iSFV_1184.SFV_0380 Bacteria 47PCJ@768503,4NNUC@976,COG0054@1,COG0054@2 NA|NA|NA H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin MAG.T22.3_00845 1239962.C943_03224 6.6e-117 426.8 Cytophagia ko:K08309,ko:K19804 ko00000,ko01000,ko01011 GH23 Bacteria 47Y3R@768503,4PMKI@976,COG2956@1,COG2956@2 NA|NA|NA G Tetratricopeptide repeat MAG.T22.3_00846 1239962.C943_03223 2.6e-193 681.4 Cytophagia pdhA 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 47M0Z@768503,4NF2J@976,COG1071@1,COG1071@2 NA|NA|NA C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) MAG.T22.3_00847 1239962.C943_03222 3.9e-173 614.0 Cytophagia recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K03629,ko:K07459 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 47JMB@768503,4NFHN@976,COG1195@1,COG1195@2 NA|NA|NA L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP MAG.T22.3_00848 1239962.C943_03221 1.5e-65 255.4 Cytophagia ko:K15977 ko00000 Bacteria 47R97@768503,4NSBJ@976,COG2259@1,COG2259@2 NA|NA|NA S DoxX MAG.T22.3_00849 1239962.C943_03220 2.6e-203 714.5 Bacteroidetes Bacteria 4NH2A@976,COG0526@1,COG0526@2 NA|NA|NA CO PFAM Redoxin MAG.T22.3_00850 1111730.ATTM01000005_gene148 6.9e-15 86.3 Flavobacteriia Bacteria 1IICV@117743,2C5NC@1,330P9@2,4NWKJ@976 NA|NA|NA MAG.T22.3_00851 1239962.C943_03218 6.7e-53 213.0 Bacteroidetes Bacteria 4NSF8@976,COG3668@1,COG3668@2 NA|NA|NA S Pfam Plasmid stabilisation system protein MAG.T22.3_00853 1239962.C943_03215 4.8e-204 716.8 Cytophagia oppA ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 47Y3Y@768503,4PMKP@976,COG4166@1,COG4166@2 NA|NA|NA G Belongs to the glycosyl hydrolase 43 family MAG.T22.3_00854 1239962.C943_03213 2e-163 581.6 Cytophagia GalU 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 47K6F@768503,4NF32@976,COG1209@1,COG1209@2 NA|NA|NA M Nucleotidyl transferase MAG.T22.3_00856 1239962.C943_03211 2.8e-57 227.6 Bacteroidetes glnB ko:K04751,ko:K04752 ko02020,map02020 ko00000,ko00001 Bacteria 4NQG9@976,COG0347@1,COG0347@2 NA|NA|NA K Belongs to the P(II) protein family MAG.T22.3_00857 1239962.C943_03210 2e-222 778.1 Cytophagia amtB ko:K03320 ko00000,ko02000 1.A.11 iJN678.amt2 Bacteria 47N2A@768503,4NDV2@976,COG0004@1,COG0004@2 NA|NA|NA P Ammonium Transporter Family MAG.T22.3_00858 1305737.JAFX01000001_gene3323 2e-139 502.3 Cytophagia ko:K07133 ko00000 Bacteria 47MF2@768503,4NE39@976,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) MAG.T22.3_00859 1239962.C943_03209 0.0 2081.2 Cytophagia Bacteria 47JPK@768503,4NESU@976,COG4447@1,COG4447@2 NA|NA|NA S Sortilin, neurotensin receptor 3, MAG.T22.3_00861 1239962.C943_03207 2.4e-229 801.2 Cytophagia ko:K14645 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 47U3J@768503,4NI53@976,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family MAG.T22.3_00862 1121373.KB903665_gene3085 5.3e-11 75.1 Cytophagia Bacteria 2E0EN@1,32W13@2,47VP8@768503,4NTH2@976 NA|NA|NA S Psort location Cytoplasmic, score 8.96 MAG.T22.3_00863 1443665.JACA01000005_gene493 4.7e-39 168.3 Aquimarina ko:K20460,ko:K20461 ko02010,map02010 M00813 ko00000,ko00001,ko00002,ko02000 3.A.1.124.3,3.A.1.124.4,3.A.1.124.5 Bacteria 1I6U3@117743,2YI3Y@290174,4NSB7@976,COG4200@1,COG4200@2 NA|NA|NA S ABC-2 family transporter protein MAG.T22.3_00864 1443665.JACA01000005_gene494 1.9e-76 292.7 Aquimarina ko:K20459 ko02010,map02010 M00813 ko00000,ko00001,ko00002,ko02000 3.A.1.124.3,3.A.1.124.4,3.A.1.124.5 Bacteria 1I1AY@117743,2YI9C@290174,4NFNM@976,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system MAG.T22.3_00865 1239962.C943_00841 5.2e-60 236.9 Bacteroidetes yjqA Bacteria 3172B@2,4NQ4C@976,arCOG12631@1 NA|NA|NA S Bacterial PH domain MAG.T22.3_00867 1239962.C943_00843 1.7e-57 228.4 Cytophagia 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 47R0R@768503,4NSDH@976,COG5646@1,COG5646@2 NA|NA|NA S Domain of unknown function (DU1801) MAG.T22.3_00869 1239962.C943_00845 8.1e-217 759.6 Cytophagia ko:K03299 ko00000,ko02000 2.A.8 Bacteria 47JEB@768503,4NFQH@976,COG2610@1,COG2610@2 NA|NA|NA EG H gluconate symporter and related MAG.T22.3_00870 1239962.C943_00846 2.5e-236 824.3 Cytophagia dadA 1.4.5.1 ko:K00285 ko00360,map00360 R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 Bacteria 47K8K@768503,4NEUE@976,COG0665@1,COG0665@2 NA|NA|NA E PFAM FAD dependent oxidoreductase MAG.T22.3_00871 1239962.C943_00847 3.6e-135 487.6 Cytophagia kch ko:K10716 ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 Bacteria 47NAG@768503,4NEX1@976,COG2126@1,COG2126@2 NA|NA|NA J PFAM Ion transport protein MAG.T22.3_00873 1239962.C943_00849 1.7e-119 435.3 Cytophagia lspA 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 47MEJ@768503,4NEZN@976,COG0597@1,COG0597@2 NA|NA|NA M This protein specifically catalyzes the removal of signal peptides from prolipoproteins MAG.T22.3_00874 1239962.C943_00850 0.0 2254.2 Cytophagia ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_0027,iPC815.YPO0475 Bacteria 47JWU@768503,4NEYT@976,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) MAG.T22.3_00875 1189612.A33Q_2324 1.3e-46 192.6 Cytophagia Bacteria 294EW@1,2ZRUR@2,47PT9@768503,4NPA3@976 NA|NA|NA S Protein of unknown function (DUF1569) MAG.T22.3_00876 1239962.C943_00854 5.7e-59 233.4 Cytophagia tdcF 3.5.99.10 ko:K09022 R11098,R11099 RC03275,RC03354 ko00000,ko01000 Bacteria 47QE4@768503,4NQ8M@976,COG0251@1,COG0251@2 NA|NA|NA J TIGRFAM endoribonuclease L-PSP MAG.T22.3_00877 1239962.C943_00855 6.6e-240 836.3 Cytophagia kynU GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 Bacteria 47KPP@768503,4NECS@976,COG3844@1,COG3844@2 NA|NA|NA E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively MAG.T22.3_00878 1239962.C943_00856 2e-263 914.4 Cytophagia kmo GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0019748,GO:0044550,GO:0055114 1.14.13.9 ko:K00486 ko00380,ko01100,map00380,map01100 M00038 R01960 RC00046 ko00000,ko00001,ko00002,ko01000 Bacteria 47KM9@768503,4NGIU@976,COG0654@1,COG0654@2 NA|NA|NA H Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid MAG.T22.3_00879 1189612.A33Q_4088 8.7e-73 280.0 Cytophagia Bacteria 47Y1N@768503,4NMEK@976,COG1225@1,COG1225@2 NA|NA|NA O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MAG.T22.3_00880 1189612.A33Q_4087 8.3e-58 229.9 Cytophagia trxC Bacteria 47RGU@768503,4NQ9U@976,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin MAG.T22.3_00882 1239962.C943_00860 4.5e-158 563.9 Cytophagia Bacteria 47P7Z@768503,4NMZ4@976,COG2234@1,COG2234@2 NA|NA|NA S Peptidase family M28 MAG.T22.3_00883 1239962.C943_00861 3.9e-176 624.0 Cytophagia Bacteria 2BYCP@1,2ZAHR@2,47NMK@768503,4NJ23@976 NA|NA|NA MAG.T22.3_00884 1239962.C943_00863 1.6e-100 372.1 Cytophagia yjjX GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564 iECO111_1330.ECO111_5255 Bacteria 47PDA@768503,4NRTY@976,COG1986@1,COG1986@2 NA|NA|NA F Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions MAG.T22.3_00885 1239962.C943_00864 2.5e-110 404.8 Cytophagia yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 Bacteria 47JWX@768503,4NE8Y@976,COG0217@1,COG0217@2 NA|NA|NA K transcriptional regulatory protein MAG.T22.3_00886 1239962.C943_00865 1.4e-229 802.0 Cytophagia ndh 1.6.99.3 ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 47K1Q@768503,4NE0H@976,COG1252@1,COG1252@2 NA|NA|NA C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase MAG.T22.3_00887 1239962.C943_00866 1.4e-72 278.9 Bacteria Bacteria COG2105@1,COG2105@2 NA|NA|NA F PFAM AIG2 family protein MAG.T22.3_00888 1239962.C943_00867 7.3e-47 193.4 Bacteroidetes Bacteria 2EGII@1,33AAP@2,4NXMZ@976 NA|NA|NA MAG.T22.3_00889 1239962.C943_00868 2e-100 371.7 Cytophagia Bacteria 2AHBZ@1,317NP@2,47WVY@768503,4P8VE@976 NA|NA|NA MAG.T22.3_00890 1239962.C943_00869 5.2e-102 377.1 Cytophagia Bacteria 47QQ5@768503,4NJ5M@976,COG2227@1,COG2227@2 NA|NA|NA H Methyltransferase domain MAG.T22.3_00891 1239962.C943_00870 9.4e-286 988.8 Cytophagia chlI 6.6.1.1 ko:K03405 ko00860,ko01100,ko01110,map00860,map01100,map01110 R03877 RC01012 ko00000,ko00001,ko01000 iNJ661.Rv0958 Bacteria 47JD2@768503,4NF1J@976,COG1239@1,COG1239@2 NA|NA|NA H magnesium chelatase MAG.T22.3_00892 1239962.C943_00871 2e-208 731.5 Cytophagia GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 47K13@768503,4NFMA@976,COG4867@1,COG4867@2 NA|NA|NA S von Willebrand factor, type A MAG.T22.3_00893 1239962.C943_00873 1e-180 639.4 Cytophagia MA20_41055 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 47UN9@768503,4NN3B@976,COG0628@1,COG0628@2 NA|NA|NA S Pfam:UPF0118 MAG.T22.3_00894 1189612.A33Q_4183 5e-17 93.2 Cytophagia Bacteria 2DY8T@1,348NQ@2,47VRB@768503,4P56Z@976 NA|NA|NA MAG.T22.3_00895 1239962.C943_00875 2.3e-38 164.5 Cytophagia acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Bacteria 47T1T@768503,4NVB4@976,COG1254@1,COG1254@2 NA|NA|NA C Acylphosphatase MAG.T22.3_00896 1239962.C943_00876 5.9e-33 146.4 Cytophagia Bacteria 2DNVM@1,32ZCX@2,47S2Y@768503,4NUVB@976 NA|NA|NA S Kazal type serine protease inhibitors MAG.T22.3_00897 1239962.C943_00877 0.0 1173.7 Cytophagia ko:K00612 ko00000,ko01000 Bacteria 47JR5@768503,4NEV9@976,COG2192@1,COG2192@2 NA|NA|NA O PFAM Carbamoyltransferase MAG.T22.3_00898 1239962.C943_00878 3.8e-120 438.0 Cytophagia prmB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.297,2.1.1.298 ko:K02493,ko:K07320 R10806 RC00003,RC03279 ko00000,ko01000,ko03009,ko03012 Bacteria 47PXV@768503,4NDZB@976,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif MAG.T22.3_00900 1189612.A33Q_3825 3.8e-63 248.4 Cytophagia Bacteria 2A159@1,30PB4@2,47WF9@768503,4PBWF@976 NA|NA|NA MAG.T22.3_00901 866536.Belba_0752 8.1e-80 303.5 Cytophagia Bacteria 47PHK@768503,4NIX6@976,COG0745@1,COG0745@2 NA|NA|NA KT Transcriptional regulatory protein, C terminal MAG.T22.3_00902 866536.Belba_0753 3e-118 432.2 Cytophagia Bacteria 47PG5@768503,4NI4D@976,COG0642@1,COG2205@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain MAG.T22.3_00903 1239962.C943_00879 3.5e-82 311.2 Cytophagia thiN 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 R00619 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 47MV1@768503,4NGJH@976,COG1564@1,COG1564@2 NA|NA|NA H thiamine pyrophosphokinase MAG.T22.3_00904 1239962.C943_00880 2.9e-168 597.8 Cytophagia oxyR GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001131,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0033554,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2000142,GO:2001141 ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 47JGK@768503,4NGZ5@976,COG0583@1,COG0583@2 NA|NA|NA K Bacterial regulatory helix-turn-helix protein, lysR family MAG.T22.3_00905 1239962.C943_00881 4.8e-188 663.7 Bacteroidetes Bacteria 4NG19@976,COG5297@1,COG5297@2 NA|NA|NA G Protein of unknown function (DUF1593) MAG.T22.3_00906 1239962.C943_00883 2.1e-177 628.2 Cytophagia glcU GO:0003674,GO:0005215,GO:0005355,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015149,GO:0015749,GO:0022857,GO:0034219,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1904659 ko:K05340,ko:K06216 ko00000,ko02000 2.A.7.5 Bacteria 47JEJ@768503,4NF22@976,COG4975@1,COG4975@2 NA|NA|NA G Sugar transport protein MAG.T22.3_00907 1123008.KB905700_gene2105 3e-210 738.0 Porphyromonadaceae Bacteria 22X71@171551,2FNB7@200643,4NG36@976,COG1397@1,COG1397@2 NA|NA|NA O ADP-ribosylglycohydrolase MAG.T22.3_00908 1189612.A33Q_4056 1.6e-91 342.8 Cytophagia rbsK GO:0003674,GO:0003824,GO:0004747,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019303,GO:0019321,GO:0019323,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0071704,GO:1901575 2.7.1.15 ko:K00852 ko00030,map00030 R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 iE2348C_1286.E2348C_4062,iEcDH1_1363.EcDH1_4215 Bacteria 47MN5@768503,4NENQ@976,COG0524@1,COG0524@2 NA|NA|NA H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway MAG.T22.3_00909 1239962.C943_00885 2.7e-257 894.0 Cytophagia Bacteria 47K7H@768503,4NGHJ@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.3_00910 1239962.C943_00886 5.1e-164 583.6 Cytophagia Bacteria 47NJX@768503,4NJ3Z@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T22.3_00911 1239962.C943_00887 4.8e-229 800.0 Cytophagia Bacteria 47K5E@768503,4NMEK@976,COG0526@1,COG0526@2,COG1225@1,COG1225@2 NA|NA|NA CO Redoxin MAG.T22.3_00912 1239962.C943_00890 1.5e-80 305.4 Cytophagia ko:K06893 ko00000 Bacteria 47R4P@768503,4NQGX@976,COG3631@1,COG3631@2 NA|NA|NA S SnoaL-like domain MAG.T22.3_00913 1239962.C943_00892 1e-11 75.1 Bacteroidetes Bacteria 4PNWQ@976,COG2908@1,COG2908@2 NA|NA|NA S Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T22.3_00914 1239962.C943_00892 2.1e-222 778.1 Bacteroidetes Bacteria 4PNWQ@976,COG2908@1,COG2908@2 NA|NA|NA S Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T22.3_00915 1189612.A33Q_2737 9.3e-166 589.7 Cytophagia cyoE ko:K06921 ko00000 Bacteria 47VKT@768503,4NGM3@976,COG1672@1,COG1672@2 NA|NA|NA S ATPase (AAA superfamily) MAG.T22.3_00916 1239962.C943_00895 5.9e-160 570.1 Cytophagia 2.7.7.53 ko:K02503,ko:K19710 ko00230,map00230 R00126,R01618 RC00002,RC02753,RC02795 ko00000,ko00001,ko01000,ko04147 Bacteria 47NSJ@768503,4NEYS@976,COG0500@1,COG0500@2,COG0537@1,COG0537@2 NA|NA|NA FGQ HIT domain MAG.T22.3_00917 1239962.C943_00896 4.2e-166 590.9 Bacteria Bacteria COG1403@1,COG1403@2 NA|NA|NA V endonuclease activity MAG.T22.3_00918 1123057.P872_12670 7e-24 117.9 Cytophagia Bacteria 2C9V5@1,2Z8F9@2,47S8V@768503,4NG2N@976 NA|NA|NA MAG.T22.3_00919 929703.KE386491_gene1033 8.1e-36 156.8 Cytophagia Bacteria 47QG9@768503,4NRQT@976,COG5485@1,COG5485@2 NA|NA|NA S SnoaL-like domain MAG.T22.3_00920 1121481.AUAS01000003_gene3703 1.3e-48 199.5 Cytophagia yqeH ko:K21907 ko00000,ko03000 Bacteria 47SXW@768503,4NZPE@976,COG2771@1,COG2771@2 NA|NA|NA K luxR family MAG.T22.3_00921 1123278.KB893572_gene2244 9.4e-51 207.2 Cytophagia melR GO:0001047,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.1.31.1,3.2.2.21 ko:K01174,ko:K03490,ko:K13529,ko:K15051 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 Bacteria 47KQ8@768503,4PNWY@976,COG2169@1,COG2169@2 NA|NA|NA K Helix-turn-helix domain MAG.T22.3_00922 1239962.C943_00893 0.0 2734.5 Cytophagia 3.6.4.12 ko:K03654,ko:K13730 ko03018,ko05100,map03018,map05100 ko00000,ko00001,ko01000,ko03400 Bacteria 47U20@768503,4NIAS@976,COG0210@1,COG0210@2,COG0514@1,COG0514@2 NA|NA|NA L Viral (Superfamily 1) RNA helicase MAG.T22.3_00923 1239962.C943_00905 0.0 1550.4 Cytophagia Bacteria 47JEM@768503,4NE60@976,COG1506@1,COG1506@2 NA|NA|NA E Prolyl oligopeptidase family MAG.T22.3_00924 1239962.C943_00906 5.7e-241 839.7 Cytophagia pkn1 Bacteria 47JSB@768503,4NE51@976,COG1262@1,COG1262@2 NA|NA|NA S TIGRFAM gliding motility-associated lipoprotein GldJ MAG.T22.3_00925 1239962.C943_00908 0.0 2149.4 Cytophagia mfd 2.4.1.129,3.4.16.4 ko:K03723,ko:K05365 ko00550,ko03420,map00550,map03420 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011,ko03400 GT51 Bacteria 47K49@768503,4NEPA@976,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site MAG.T22.3_00926 1239962.C943_00909 7.2e-104 383.3 Cytophagia ctaE 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 Bacteria 47RAE@768503,4NU0C@976,COG1845@1,COG1845@2 NA|NA|NA C cytochrome c oxidase subunit III MAG.T22.3_00927 1239962.C943_00910 3e-75 287.7 Cytophagia ko:K07071 ko00000 Bacteria 47QF6@768503,4NQDG@976,COG4276@1,COG4276@2 NA|NA|NA S Pfam Polyketide cyclase dehydrase and lipid transport MAG.T22.3_00928 1239962.C943_00911 1.9e-83 315.1 Cytophagia fur GO:0000976,GO:0001067,GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 ko:K03711 ko00000,ko03000 Bacteria 47QUM@768503,4NRED@976,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family MAG.T22.3_00930 1239962.C943_00914 3.3e-228 797.3 Cytophagia Bacteria 47K87@768503,4NEF4@976,COG0793@1,COG0793@2 NA|NA|NA M PDZ DHR GLGF domain protein MAG.T22.3_00931 1239962.C943_00916 0.0 2160.6 Cytophagia 2.1.1.80,2.7.13.3,3.1.1.61 ko:K02003,ko:K02484,ko:K13924,ko:K14986 ko02020,ko02030,map02020,map02030 M00258,M00506,M00524 ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035 3.A.1 Bacteria 47JSC@768503,4NFC3@976,COG2202@1,COG2202@2,COG2203@1,COG2203@2,COG4251@1,COG4251@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain MAG.T22.3_00932 1239962.C943_00917 5e-102 377.1 Cytophagia lemA ko:K03744 ko00000 Bacteria 47JGT@768503,4NMD3@976,COG1704@1,COG1704@2 NA|NA|NA S PFAM LemA family MAG.T22.3_00933 1239962.C943_00918 1.3e-75 288.9 Cytophagia Z012_08985 ko:K08988 ko00000 Bacteria 47QCD@768503,4NQIT@976,COG3762@1,COG3762@2 NA|NA|NA S TPM domain MAG.T22.3_00934 1239962.C943_00919 3.3e-128 464.5 Cytophagia Z012_08980 3.4.24.3 ko:K01387,ko:K06872 ko00000,ko01000,ko01002,ko02042 Bacteria 47NDD@768503,4NF4P@976,COG1512@1,COG1512@2 NA|NA|NA S Beta-propeller domains of methanol dehydrogenase type MAG.T22.3_00936 1120965.AUBV01000001_gene3240 1.1e-28 132.5 Cytophagia Bacteria 47X0I@768503,4PBCV@976,COG3668@1,COG3668@2 NA|NA|NA S Plasmid stabilization system MAG.T22.3_00939 1288963.ADIS_0431 2.7e-26 124.0 Bacteria Bacteria 2EIWJ@1,33CMX@2 NA|NA|NA MAG.T22.3_00940 1239962.C943_00924 4.1e-130 470.7 Cytophagia comF Bacteria 47PYN@768503,4NNI1@976,COG1040@1,COG1040@2 NA|NA|NA S TIGRFAM comF family protein MAG.T22.3_00941 1239962.C943_00925 2.4e-59 234.6 Cytophagia rnhA 3.1.26.4,4.1.1.44 ko:K01607,ko:K03469 ko00362,ko01100,ko01120,ko01220,ko03030,map00362,map01100,map01120,map01220,map03030 R03470 RC00938 ko00000,ko00001,ko01000,ko03032 Bacteria 47QTE@768503,4NNRB@976,COG0599@1,COG0599@2 NA|NA|NA S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity MAG.T22.3_00942 1239962.C943_00926 9.6e-64 249.2 Cytophagia Bacteria 29D8R@1,3006P@2,47R44@768503,4NNGD@976 NA|NA|NA MAG.T22.3_00943 1239962.C943_00927 1.7e-147 528.5 Cytophagia xth 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 47KRK@768503,4NEY3@976,COG0708@1,COG0708@2 NA|NA|NA L PFAM Endonuclease Exonuclease phosphatase MAG.T22.3_00944 1239962.C943_00928 1e-66 259.2 Cytophagia rsbW 2.7.11.1 ko:K04757,ko:K08282 ko00000,ko01000,ko01001,ko03021 Bacteria 47QUX@768503,4NRAA@976,COG2172@1,COG2172@2 NA|NA|NA T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MAG.T22.3_00945 1239962.C943_00929 9.5e-71 272.7 Cytophagia ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 47Q9Q@768503,4NS93@976,COG0319@1,COG0319@2 NA|NA|NA S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA MAG.T22.3_00946 1239962.C943_00930 0.0 1217.6 Cytophagia gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 ko:K03495 R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 Bacteria 47JCG@768503,4NFNH@976,COG0445@1,COG0445@2 NA|NA|NA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 MAG.T22.3_00947 1239962.C943_00931 1.4e-103 382.9 Cytophagia Bacteria 47K52@768503,4NGVF@976,COG2227@1,COG2227@2 NA|NA|NA H Methyltransferase type 11 MAG.T22.3_00948 1239962.C943_00932 7.4e-308 1062.4 Cytophagia Bacteria 47KXU@768503,4NGPF@976,COG4704@1,COG4704@2 NA|NA|NA S Bacterial Ig-like domain MAG.T22.3_00949 1239962.C943_00933 0.0 1180.2 Cytophagia fadD 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 47K61@768503,4NEA4@976,COG1022@1,COG1022@2 NA|NA|NA I AMP-binding enzyme MAG.T22.3_00950 1239962.C943_00934 2.1e-82 311.6 Cytophagia marR Bacteria 47QHS@768503,4NNK7@976,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator, MarR family MAG.T22.3_00951 1239962.C943_00935 0.0 1579.3 Cytophagia fadB 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782,ko:K07516 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04743,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 iYO844.BSU32840 Bacteria 47ME4@768503,4NF9D@976,COG1024@1,COG1024@2,COG1250@1,COG1250@2 NA|NA|NA I 3-hydroxyacyl-CoA dehydrogenase MAG.T22.3_00952 1239962.C943_00936 3.5e-61 240.7 Cytophagia Bacteria 2DNS7@1,32YWC@2,47SJ7@768503,4NSJ6@976 NA|NA|NA J 23S rRNA-intervening sequence protein MAG.T22.3_00953 1239962.C943_00937 1.2e-216 758.8 Cytophagia fadA 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 Bacteria 47JQD@768503,4NE3Q@976,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family MAG.T22.3_00954 1189612.A33Q_2703 1.1e-30 139.4 Cytophagia 2.6.1.102 ko:K13010 ko00520,map00520 R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 47YAS@768503,4PKRF@976,COG0399@1,COG0399@2 NA|NA|NA M 23S rRNA-intervening sequence protein MAG.T22.3_00955 1239962.C943_00938 0.0 1152.9 Cytophagia fadE 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 Bacteria 47KH2@768503,4NG2G@976,COG1960@1,COG1960@2 NA|NA|NA I acyl-CoA dehydrogenase MAG.T22.3_00956 1121373.KB903643_gene3507 2.3e-67 261.9 Bacteroidetes Bacteria 28NF4@1,2ZBHH@2,4NM0Y@976 NA|NA|NA MAG.T22.3_00958 1239962.C943_00943 4.4e-163 580.5 Cytophagia 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 Bacteria 47UAS@768503,4PPR4@976,COG2227@1,COG2227@2 NA|NA|NA H Methionine biosynthesis protein MetW MAG.T22.3_00959 1239962.C943_00944 2e-161 575.1 Bacteria ko:K07011 ko00000 Bacteria COG1216@1,COG1216@2 NA|NA|NA V Glycosyl transferase, family 2 MAG.T22.3_00960 1239962.C943_00945 8.1e-206 723.0 Cytophagia ko:K03328 ko00000 2.A.66.2 Bacteria 47PQY@768503,4NFF1@976,COG2244@1,COG2244@2 NA|NA|NA S Membrane protein involved in the export of O-antigen and teichoic acid MAG.T22.3_00961 1239962.C943_00946 4.1e-187 660.6 Cytophagia ko:K07011 ko00000 Bacteria 47N66@768503,4NH8F@976,COG3206@1,COG3206@2 NA|NA|NA M lipopolysaccharide biosynthesis protein MAG.T22.3_00962 1239962.C943_00947 0.0 1605.9 Cytophagia kpsD ko:K01991 ko02026,map02026 ko00000,ko00001,ko02000 1.B.18 Bacteria 47K4B@768503,4NEXJ@976,COG1596@1,COG1596@2 NA|NA|NA M Polysaccharide biosynthesis export protein MAG.T22.3_00963 1239962.C943_00949 2.8e-172 611.3 Cytophagia Bacteria 47K59@768503,4NGWY@976,COG0535@1,COG0535@2 NA|NA|NA C Radical SAM MAG.T22.3_00964 1239962.C943_00950 3.9e-165 587.4 Cytophagia Bacteria 47P9G@768503,4NH49@976,COG2335@1,COG2335@2 NA|NA|NA M PFAM Fasciclin domain MAG.T22.3_00965 1239962.C943_00951 2.5e-172 611.3 Cytophagia gldB Bacteria 47N7G@768503,4NFZP@976,COG5504@1,COG5504@2 NA|NA|NA O Gliding motility protein, GldB MAG.T22.3_00966 1239962.C943_00952 6.2e-195 686.8 Cytophagia Bacteria 47KFJ@768503,4NI16@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase 4-like domain MAG.T22.3_00967 1239962.C943_00953 0.0 1113.6 Cytophagia 2.1.1.21,6.3.5.4 ko:K01953,ko:K22081 ko00250,ko00680,ko01100,ko01110,ko01120,map00250,map00680,map01100,map01110,map01120 R00578,R01586 RC00010,RC00554 ko00000,ko00001,ko01000,ko01002 Bacteria 47JQB@768503,4NHMX@976,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase MAG.T22.3_00968 1239962.C943_00954 1.1e-121 442.6 Cytophagia nth 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 47JCH@768503,4NFF3@976,COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate MAG.T22.3_00969 1239962.C943_00955 1e-159 569.3 Cytophagia 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 47STK@768503,4NFTX@976,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold MAG.T22.3_00970 1239962.C943_00956 1.1e-36 158.7 Cytophagia Bacteria 2E6G6@1,3313F@2,47S4P@768503,4NWM7@976 NA|NA|NA MAG.T22.3_00971 1239962.C943_00957 1.5e-106 392.1 Cytophagia rpoE ko:K03088 ko00000,ko03021 Bacteria 47KW3@768503,4NF93@976,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T22.3_00972 1239962.C943_00958 1.1e-36 158.7 Cytophagia Bacteria 2DMPT@1,32SXV@2,47R1K@768503,4PKGT@976 NA|NA|NA S Domain of unknown function (DUF3127) MAG.T22.3_00973 1239962.C943_00959 2.1e-71 275.0 Cytophagia Bacteria 2BA9N@1,323PV@2,47PM5@768503,4NNB5@976 NA|NA|NA MAG.T22.3_00974 1239962.C943_03795 2.1e-80 305.1 Cytophagia purE GO:0008150,GO:0040007 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iJN678.purE,iNJ661.Rv3275c Bacteria 47PQS@768503,4NME9@976,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) MAG.T22.3_00975 1239962.C943_03794 2.3e-210 738.0 Cytophagia purK GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477 Bacteria 47JH8@768503,4NEGE@976,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) MAG.T22.3_00976 1239962.C943_03793 2.2e-14 84.0 Cytophagia Bacteria 2DIK3@1,303HF@2,47WZ8@768503,4PC8Q@976 NA|NA|NA MAG.T22.3_00977 1239962.C943_03792 3.1e-256 891.0 Cytophagia mutS ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 47KGC@768503,4NE6X@976,COG0249@1,COG0249@2 NA|NA|NA L PFAM DNA mismatch repair protein MutS MAG.T22.3_00978 1239962.C943_03791 2.1e-71 275.0 Cytophagia ko:K09950 ko00000 Bacteria 47P8H@768503,4NMZ8@976,COG3495@1,COG3495@2 NA|NA|NA S Protein conserved in bacteria MAG.T22.3_00979 1123057.P872_08165 8e-61 240.7 Cytophagia Bacteria 28M3Z@1,32ZEY@2,47SGM@768503,4NUZS@976 NA|NA|NA MAG.T22.3_00980 1239962.C943_03789 1.2e-88 332.4 Cytophagia Bacteria 2E0QA@1,32W90@2,47RSZ@768503,4NUC6@976 NA|NA|NA MAG.T22.3_00981 1239962.C943_03788 5.1e-87 327.0 Cytophagia recX GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 ko:K03565,ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003,ko03400 GT4 Bacteria 47QBK@768503,4NSAS@976,COG2137@1,COG2137@2 NA|NA|NA S Modulates RecA activity MAG.T22.3_00982 1239962.C943_03787 2.1e-137 495.0 Cytophagia tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iJN746.PP_4715 Bacteria 47KW6@768503,4NE2F@976,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) MAG.T22.3_00983 1239962.C943_03786 1.4e-155 555.4 Cytophagia prmA ko:K02687 ko00000,ko01000,ko03009 Bacteria 47JQR@768503,4NFRW@976,COG2264@1,COG2264@2 NA|NA|NA J Ribosomal protein L11 methyltransferase MAG.T22.3_00984 866536.Belba_1072 1.2e-17 95.1 Cytophagia Bacteria 2DPUD@1,333EJ@2,47RWD@768503,4NUNI@976 NA|NA|NA MAG.T22.3_00985 1239962.C943_03784 6.8e-209 733.0 Cytophagia Bacteria 47JUU@768503,4NF0H@976,COG3177@1,COG3177@2 NA|NA|NA S Domain of unknown function (DUF4172) MAG.T22.3_00986 1048983.EL17_14165 2.2e-12 79.7 Cytophagia Bacteria 2DEMC@1,2ZNFY@2,47WD4@768503,4P82Z@976 NA|NA|NA MAG.T22.3_00988 1239962.C943_03783 1.5e-97 362.1 Cytophagia Bacteria 28H8R@1,2Z7KJ@2,47NH9@768503,4NGZN@976 NA|NA|NA MAG.T22.3_00989 1239962.C943_03782 9.9e-132 476.1 Bacteria Bacteria COG0517@1,COG0517@2 NA|NA|NA S IMP dehydrogenase activity MAG.T22.3_00990 1239962.C943_03781 8.4e-137 493.0 Cytophagia Bacteria 47NTC@768503,4NFDX@976,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T22.3_00991 1239962.C943_03780 1.8e-201 708.4 Cytophagia Bacteria 47JR4@768503,4NIDT@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T22.3_00992 1239962.C943_03779 0.0 1587.8 Cytophagia Bacteria 47JIJ@768503,4NEZ5@976,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C Membrane-bound dehydrogenase domain protein MAG.T22.3_00993 694427.Palpr_2226 5.7e-22 112.1 Porphyromonadaceae ko:K21571 ko00000 Bacteria 22Y91@171551,2FTSH@200643,4NHDQ@976,COG3656@1,COG3656@2 NA|NA|NA S Fibronectin type 3 domain MAG.T22.3_00994 1239962.C943_03777 7.8e-235 819.3 Bacteroidetes sqr GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0042802,GO:0044237,GO:0045333,GO:0055114 1.8.5.4 ko:K17218 ko00920,map00920 R10152 RC03155 ko00000,ko00001,ko01000 Bacteria 4NFUW@976,COG0446@1,COG0446@2 NA|NA|NA S Pyridine nucleotide-disulphide oxidoreductase MAG.T22.3_00995 1239962.C943_03776 6.1e-143 513.5 Cytophagia mazG GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 ko:K02428,ko:K02499,ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323 RC00002 ko00000,ko00001,ko01000,ko03036 iJN678.sll1005 Bacteria 47K4M@768503,4NEA3@976,COG1694@1,COG3956@2 NA|NA|NA S PFAM MazG nucleotide pyrophosphohydrolase MAG.T22.3_00996 1239962.C943_03775 1.3e-34 151.8 Cytophagia Bacteria 2E5GR@1,3308C@2,47S69@768503,4NUPC@976 NA|NA|NA MAG.T22.3_00997 1239962.C943_03774 1.6e-260 904.8 Cytophagia glmM 5.4.2.10,5.4.2.2,5.4.2.8 ko:K01840,ko:K03431,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R02060,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 47KR9@768503,4NG3H@976,COG1109@1,COG1109@2 NA|NA|NA G Phosphoglucomutase phosphomannomutase alpha beta alpha domain I MAG.T22.3_00998 1239962.C943_03773 2.6e-211 741.1 Cytophagia iscS 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 47MAZ@768503,4NFF6@976,COG1104@1,COG1104@2 NA|NA|NA E PFAM aminotransferase class V MAG.T22.3_00999 1239962.C943_03708 1.4e-39 168.7 Cytophagia rlmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 ko:K00783 ko00000,ko01000,ko03009 Bacteria 47Q9Z@768503,4NMFP@976,COG1576@1,COG1576@2 NA|NA|NA J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA MAG.T22.3_01000 1239962.C943_03769 7.5e-216 756.1 Cytophagia Bacteria 47JP1@768503,4NERD@976,COG3239@1,COG3239@2 NA|NA|NA I fatty acid desaturase MAG.T22.3_01001 1239962.C943_03767 2.8e-127 461.5 Cytophagia Bacteria 2FG5W@1,3482C@2,47VV9@768503,4P5PR@976 NA|NA|NA MAG.T22.3_01002 1239962.C943_03766 0.0 1176.4 Cytophagia Bacteria 47KNK@768503,4NEF2@976,COG2303@1,COG2303@2 NA|NA|NA E Choline dehydrogenase and related MAG.T22.3_01003 1239962.C943_03765 4.4e-92 344.0 Cytophagia Bacteria 2CDAN@1,309X8@2,47Q2E@768503,4NTY4@976 NA|NA|NA S Gluconate 2-dehydrogenase subunit 3 MAG.T22.3_01004 1239962.C943_03763 0.0 1840.9 Cytophagia ko:K02109,ko:K09800 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko02000 3.A.2.1 Bacteria 47KBD@768503,4NEJQ@976,COG0711@1,COG0711@2,COG2982@1,COG2982@2 NA|NA|NA M AsmA-like C-terminal region MAG.T22.3_01005 1239962.C943_03762 3e-150 537.7 Cytophagia suhB 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 47K2K@768503,4NI6D@976,COG0483@1,COG0483@2 NA|NA|NA G Inositol monophosphatase MAG.T22.3_01006 1239962.C943_03761 1.2e-207 728.8 Cytophagia hemH GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 Bacteria 47JH0@768503,4NE83@976,COG0276@1,COG0276@2 NA|NA|NA H Catalyzes the ferrous insertion into protoporphyrin IX MAG.T22.3_01007 1239962.C943_03759 0.0 1099.7 Cytophagia Bacteria 47M9C@768503,4NF4Q@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase domain protein MAG.T22.3_01008 1239962.C943_03758 5.6e-83 313.5 Bacteroidetes 1.8.5.2 ko:K16937 ko00920,ko01120,map00920,map01120 R07177 ko00000,ko00001,ko01000 3.D.4.9 Bacteria 295NE@1,2ZSZT@2,4NPQK@976 NA|NA|NA S DoxX MAG.T22.3_01010 1239962.C943_03756 1.1e-170 605.9 Cytophagia gnl GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47KMQ@768503,4NIMX@976,COG3386@1,COG3386@2 NA|NA|NA G PFAM SMP-30 Gluconolaconase MAG.T22.3_01011 1239962.C943_03755 0.0 1473.0 Cytophagia katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 Bacteria 47KR2@768503,4NG30@976,COG0376@1,COG0376@2 NA|NA|NA P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity MAG.T22.3_01012 1239962.C943_03754 1.8e-156 558.5 Cytophagia yneE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08994 ko00000,ko02000 1.A.46.2 Bacteria 47N85@768503,4NEB1@976,COG3781@1,COG3781@2 NA|NA|NA S Bestrophin, RFP-TM, chloride channel MAG.T22.3_01013 1239962.C943_03752 4.7e-74 283.9 Bacteroidetes Bacteria 2EJAK@1,33D1S@2,4NYPK@976 NA|NA|NA MAG.T22.3_01014 1120965.AUBV01000012_gene1391 8.7e-73 279.6 Bacteria greB GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010604,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031437,GO:0031439,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903311,GO:1903313,GO:1903506,GO:2000112,GO:2001141 ko:K04760 ko00000,ko03021 Bacteria COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus MAG.T22.3_01015 1239962.C943_03749 1.1e-128 466.1 Cytophagia ccrA 3.5.2.6 ko:K17837 ko01501,map01501 R06363 RC01499 ko00000,ko00001,ko01000 Bacteria 47MDW@768503,4NPPW@976,COG0491@1,COG0491@2 NA|NA|NA S Metallo-beta-lactamase superfamily MAG.T22.3_01017 1239962.C943_03129 5.1e-259 899.8 Cytophagia hemN GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 ko:K02495 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R06895 RC00884 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_3134,iZ_1308.Z5403 Bacteria 47K3T@768503,4NEY5@976,COG0635@1,COG0635@2 NA|NA|NA H Belongs to the anaerobic coproporphyrinogen-III oxidase family MAG.T22.3_01018 1239962.C943_03128 7.5e-269 932.6 Cytophagia Bacteria 47JIW@768503,4NIF1@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha beta domain MAG.T22.3_01019 1239962.C943_03127 6.9e-206 723.0 Cytophagia Bacteria 47ME7@768503,4NFY3@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain MAG.T22.3_01020 1239962.C943_03126 6.9e-130 469.9 Cytophagia ko:K01420,ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 Bacteria 47JY7@768503,4NFB1@976,COG0664@1,COG0664@2 NA|NA|NA K Transcriptional regulator, Crp Fnr family MAG.T22.3_01021 1239962.C943_03125 6.4e-82 310.1 Cytophagia CP_0160 Bacteria 47QPJ@768503,4NNKI@976,COG4096@1,COG4096@2 NA|NA|NA V Type I restriction enzyme R Protein MAG.T22.3_01022 1239962.C943_03124 3.1e-127 461.1 Cytophagia comEA ko:K02237 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 47KXV@768503,4NK4K@976,COG1555@1,COG1555@2 NA|NA|NA L Helix-hairpin-helix motif MAG.T22.3_01023 1239962.C943_03123 1.4e-229 802.0 Cytophagia hemA GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 ko:K02407,ko:K02492 ko00860,ko01100,ko01110,ko01120,ko02040,map00860,map01100,map01110,map01120,map02040 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000,ko02035 Bacteria 47JF5@768503,4NFTY@976,COG0373@1,COG0373@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) MAG.T22.3_01024 1189612.A33Q_2182 7.4e-90 336.7 Cytophagia Bacteria 47XT1@768503,4NQK5@976,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like MAG.T22.3_01027 1268240.ATFI01000009_gene1893 2.9e-71 275.8 Bacteroidaceae Bacteria 2FPA4@200643,4AKI6@815,4NE5D@976,COG3209@1,COG3209@2 NA|NA|NA M COG COG3209 Rhs family protein MAG.T22.3_01029 1239962.C943_02299 8.4e-213 746.5 Cytophagia Bacteria 47XSD@768503,4NJ6B@976,COG5263@1,COG5263@2 NA|NA|NA S WG containing repeat MAG.T22.3_01030 1239962.C943_02298 9.6e-146 523.1 Cytophagia yqfA Bacteria 47KKM@768503,4NGG6@976,COG4864@1,COG4864@2 NA|NA|NA S UPF0365 protein MAG.T22.3_01031 1239962.C943_02297 8.5e-73 279.6 Cytophagia Bacteria 47S4B@768503,4NW09@976,COG1030@1,COG1030@2 NA|NA|NA O NfeD-like C-terminal, partner-binding MAG.T22.3_01032 1239962.C943_02296 1.5e-283 981.5 Cytophagia proS GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 47JTQ@768503,4NEAF@976,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) MAG.T22.3_01033 1239962.C943_02295 2.3e-153 548.9 Bacteroidetes Bacteria 2CJG0@1,332HN@2,4NM27@976 NA|NA|NA MAG.T22.3_01034 1239962.C943_02294 3.3e-283 980.3 Cytophagia Bacteria 47K28@768503,4NFS7@976,COG2067@1,COG2067@2 NA|NA|NA I PFAM Outer membrane protein transport protein (OMPP1 FadL TodX) MAG.T22.3_01035 1239962.C943_02293 8.4e-85 319.7 Cytophagia aroK 2.7.1.71,4.2.3.4 ko:K00891,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 47QWF@768503,4NQ73@976,COG0703@1,COG0703@2 NA|NA|NA F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate MAG.T22.3_01036 1239962.C943_02292 2.8e-191 674.5 Cytophagia tpiA 5.3.1.1 ko:K01803,ko:K15977 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47JTZ@768503,4NGNF@976,COG2259@1,COG2259@2 NA|NA|NA S DoxX family MAG.T22.3_01037 1239962.C943_02291 1.4e-98 365.5 Cytophagia Bacteria 28HFG@1,2Z7RJ@2,47PDT@768503,4NFNY@976 NA|NA|NA S Domain of Unknown Function (DUF1599) MAG.T22.3_01038 1239962.C943_02290 1.1e-153 549.3 Cytophagia folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15,2.7.6.3 ko:K00796,ko:K13941 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503 RC00002,RC00017,RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 Bacteria 47MUJ@768503,4NEYJ@976,COG0294@1,COG0294@2 NA|NA|NA H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives MAG.T22.3_01039 1239962.C943_02289 4e-148 530.8 Cytophagia dacA GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 2.7.7.85 ko:K18672 ko00000,ko01000 Bacteria 47JT6@768503,4NG3Z@976,COG1624@1,COG1624@2 NA|NA|NA S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria MAG.T22.3_01040 1239962.C943_02288 3.5e-28 130.2 Cytophagia cspB ko:K03704 ko00000,ko03000 Bacteria 47S4F@768503,4NURE@976,COG1278@1,COG1278@2 NA|NA|NA K PFAM Cold-shock protein, DNA-binding MAG.T22.3_01041 1239962.C943_02287 6e-85 320.1 Cytophagia sixA ko:K08296 ko00000,ko01000 Bacteria 47R7I@768503,4NQFM@976,COG2062@1,COG2062@2 NA|NA|NA T PFAM Phosphoglycerate mutase MAG.T22.3_01042 1239962.C943_02286 3e-120 438.0 Cytophagia Bacteria 47Q7Q@768503,4NNJ9@976,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase MAG.T22.3_01043 1239962.C943_02285 2.6e-245 854.4 Cytophagia hslU GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03667 ko00000,ko03110 Bacteria 47JSG@768503,4NFI2@976,COG1220@1,COG1220@2 NA|NA|NA O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis MAG.T22.3_01044 1239962.C943_02284 0.0 1585.9 Cytophagia lon 3.4.21.53 ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria 47M84@768503,4NE1G@976,COG0466@1,COG0466@2 NA|NA|NA O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner MAG.T22.3_01045 1124780.ANNU01000038_gene161 2.1e-09 71.2 Bacteria Bacteria COG3055@1,COG3055@2,COG5184@1,COG5184@2 NA|NA|NA G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses MAG.T22.3_01047 1239962.C943_02279 1.4e-240 838.6 Cytophagia rseP ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria 47JDH@768503,4NEAR@976,COG0750@1,COG0750@2 NA|NA|NA M zinc metalloprotease MAG.T22.3_01048 1239962.C943_02278 2e-211 741.5 Cytophagia dxr GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iHN637.CLJU_RS06420,iNJ661.Rv2870c,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188 Bacteria 47K0A@768503,4NG0S@976,COG0743@1,COG0743@2 NA|NA|NA I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) MAG.T22.3_01049 1239962.C943_02276 1.2e-263 915.2 Cytophagia degQ 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 47NTS@768503,4NFCS@976,COG0265@1,COG0265@2 NA|NA|NA O Trypsin MAG.T22.3_01050 1123057.P872_24895 8.3e-35 153.3 Cytophagia Bacteria 2DTEZ@1,33K2M@2,47YGW@768503,4PP5V@976 NA|NA|NA S Nucleotidyltransferase substrate binding protein like MAG.T22.3_01051 1239962.C943_02273 1.3e-227 795.4 Cytophagia Bacteria 47K9R@768503,4NG4W@976,COG5276@1,COG5276@2 NA|NA|NA S LVIVD repeat MAG.T22.3_01052 1239962.C943_02272 1e-100 372.9 Cytophagia Bacteria 2DM96@1,327TJ@2,47S7G@768503,4NRCS@976 NA|NA|NA MAG.T22.3_01053 1239962.C943_02266 3.4e-129 467.6 Cytophagia ecsA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 47K40@768503,4NJ0D@976,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities MAG.T22.3_01054 1239962.C943_02265 6.1e-299 1032.7 Cytophagia Bacteria 2C5PV@1,32RG0@2,47NI6@768503,4NI9E@976 NA|NA|NA S Putative ABC exporter MAG.T22.3_01055 1239962.C943_02264 5.6e-83 313.5 Cytophagia Bacteria 47Q3A@768503,4NQ61@976,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain MAG.T22.3_01056 1239962.C943_02263 3.6e-229 800.4 Cytophagia Bacteria 47M7W@768503,4NFWE@976,COG0454@1,COG0456@2 NA|NA|NA K Psort location Cytoplasmic, score 8.96 MAG.T22.3_01057 1239962.C943_02262 3.8e-187 660.6 Cytophagia pfkB 2.7.1.15,2.7.1.4 ko:K00847,ko:K00852 ko00030,ko00051,ko00500,ko00520,ko01100,map00030,map00051,map00500,map00520,map01100 R00760,R00867,R01051,R02750,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 47NUW@768503,4NIHI@976,COG0524@1,COG0524@2 NA|NA|NA G Belongs to the carbohydrate kinase PfkB family MAG.T22.3_01058 1239962.C943_02261 4.1e-289 1000.0 Cytophagia Bacteria 47MXY@768503,4NFUI@976,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase class C and other penicillin binding MAG.T22.3_01059 1239962.C943_02259 2e-274 951.0 Cytophagia Bacteria 47TDN@768503,4NEN5@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.3_01060 1239962.C943_02258 5.7e-118 431.8 Cytophagia blaR1 Bacteria 47JQV@768503,4NKKC@976,COG3064@1,COG3064@2,COG4219@1,COG4219@2 NA|NA|NA KT PFAM Peptidase M56, BlaR1 MAG.T22.3_01061 1239962.C943_02257 2e-56 224.9 Cytophagia blal Bacteria 47R7N@768503,4NSQR@976,COG3682@1,COG3682@2 NA|NA|NA K PFAM Penicillinase repressor MAG.T22.3_01062 1239962.C943_02256 3.1e-110 404.4 Cytophagia Bacteria 47RNQ@768503,4NUAF@976,COG2253@1,COG2253@2 NA|NA|NA S Nucleotidyl transferase AbiEii toxin, Type IV TA system MAG.T22.3_01063 1189612.A33Q_2412 3.3e-41 174.1 Cytophagia Bacteria 2C2TP@1,33BV9@2,47T6I@768503,4NXY4@976 NA|NA|NA MAG.T22.3_01064 1239962.C943_02254 1.9e-121 442.2 Cytophagia Bacteria 47P76@768503,4NMX4@976,COG3332@1,COG3332@2 NA|NA|NA S Transport and Golgi organisation 2 MAG.T22.3_01065 1239962.C943_02253 1.3e-182 645.6 Cytophagia ypdA 1.18.1.2,1.19.1.1,1.8.1.9 ko:K00384,ko:K21567 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 Bacteria 47MQ3@768503,4NDVS@976,COG0492@1,COG0492@2 NA|NA|NA O Pyridine nucleotide-disulphide oxidoreductase MAG.T22.3_01066 1239962.C943_02252 0.0 1171.8 Cytophagia yfmR ko:K15738 ko00000,ko02000 3.A.1.120.6 Bacteria 47JCA@768503,4NES5@976,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter MAG.T22.3_01067 714943.Mucpa_1927 1.5e-23 115.5 Sphingobacteriia ko:K06218 ko00000,ko02048 Bacteria 1IU0G@117747,4NW0W@976,COG2026@1,COG2026@2 NA|NA|NA DJ Psort location Cytoplasmic, score 8.96 MAG.T22.3_01069 1239962.C943_02251 4.9e-201 706.8 Cytophagia Bacteria 47JVD@768503,4NH92@976,COG3391@1,COG3391@2 NA|NA|NA S NHL repeat containing protein MAG.T22.3_01070 1239962.C943_02250 5.3e-150 537.0 Cytophagia Bacteria 47NNJ@768503,4NFMD@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T22.3_01072 1305737.JAFX01000001_gene2640 1.6e-43 184.1 Cytophagia Bacteria 2E3YY@1,32YVW@2,47W4W@768503,4NX9K@976 NA|NA|NA MAG.T22.3_01073 1239962.C943_02249 4.1e-130 470.7 Cytophagia plsC 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 47QIE@768503,4NG5R@976,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases MAG.T22.3_01075 1305737.JAFX01000001_gene3234 2e-09 70.5 Bacteroidetes Bacteria 4NWBP@976,COG3391@1,COG3391@2 NA|NA|NA S Domain of unknown function (DUF4221) MAG.T22.3_01077 1239962.C943_02248 0.0 1150.2 Cytophagia rpsA GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 ko:K02945,ko:K03527,ko:K12132 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011 Bacteria 47JD4@768503,4NDW9@976,COG0539@1,COG0539@2 NA|NA|NA J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence MAG.T22.3_01078 1239962.C943_02247 1.2e-195 689.1 Bacteroidetes Bacteria 2CGWC@1,339HX@2,4NX41@976 NA|NA|NA MAG.T22.3_01087 1239962.C943_00698 6.1e-222 776.5 Cytophagia psbV GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 ko:K02720 ko00195,ko01100,map00195,map01100 ko00000,ko00001,ko00194 iJN678.psbV Bacteria 47J8Z@768503,4NF0A@976,COG2010@1,COG2010@2 NA|NA|NA C PFAM Class III cytochrome C family MAG.T22.3_01088 1239962.C943_00697 0.0 2020.0 Cytophagia actB ko:K00184 ko00000 5.A.3 Bacteria 47NK7@768503,4NE5M@976,COG0437@1,COG0437@2 NA|NA|NA C 4Fe-4S dicluster domain MAG.T22.3_01089 1239962.C943_00696 2.1e-260 904.4 Cytophagia actC ko:K00185 ko00000 5.A.3 Bacteria 47K18@768503,4NE3X@976,COG5557@1,COG5557@2 NA|NA|NA C PFAM Polysulphide reductase, NrfD MAG.T22.3_01090 1239962.C943_00695 1.7e-93 348.6 Cytophagia actD Bacteria 47K4U@768503,4NEX9@976,COG2010@1,COG2010@2 NA|NA|NA C Quinol cytochrome c oxidoreductase membrane protein MAG.T22.3_01091 866536.Belba_3793 2e-90 338.6 Cytophagia actE Bacteria 47PEX@768503,4NKQI@976,COG2010@1,COG2010@2 NA|NA|NA C PFAM Cytochrome C MAG.T22.3_01092 1239962.C943_00693 3e-224 784.3 Cytophagia actF Bacteria 47JUF@768503,4NF0R@976,COG4531@1,COG4531@2 NA|NA|NA P Quinol cytochrome c oxidoreductase MAG.T22.3_01093 1239962.C943_00692 1.6e-196 691.8 Cytophagia coxM GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 47JF8@768503,4NFNF@976,COG1622@1,COG1622@2 NA|NA|NA C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) MAG.T22.3_01094 1239962.C943_00691 0.0 1220.7 Cytophagia coxN 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 Bacteria 47JBQ@768503,4NEH8@976,COG0843@1,COG0843@2 NA|NA|NA C Belongs to the heme-copper respiratory oxidase family MAG.T22.3_01095 1239962.C943_00690 8e-170 603.2 Cytophagia ctaA ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 Bacteria 47JI1@768503,4NEBR@976,COG1612@1,COG1612@2 NA|NA|NA O Cytochrome oxidase assembly protein MAG.T22.3_01096 1239962.C943_00689 2.3e-146 525.0 Cytophagia ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Bacteria 47MB0@768503,4NF5A@976,COG0109@1,COG0109@2 NA|NA|NA O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group MAG.T22.3_01097 1239962.C943_00688 8.4e-102 376.3 Cytophagia ctaE 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 Bacteria 47NS2@768503,4NFA7@976,COG1845@1,COG1845@2 NA|NA|NA C PFAM cytochrome c oxidase subunit III MAG.T22.3_01098 1239962.C943_00687 5.2e-147 526.9 Cytophagia coxP 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 Bacteria 47JVP@768503,4NDYG@976,COG1845@1,COG1845@2 NA|NA|NA C cytochrome c oxidase subunit III MAG.T22.3_01099 1239962.C943_00686 1.3e-46 192.2 Cytophagia coxQ Bacteria 47RQF@768503,4NTVI@976,COG5605@1,COG5605@2 NA|NA|NA S Prokaryotic Cytochrome C oxidase subunit IV MAG.T22.3_01100 1239962.C943_00685 1.9e-121 441.8 Cytophagia ypmQ ko:K07152,ko:K08976 ko00000,ko03029 Bacteria 47XQN@768503,4NFH2@976,COG1999@1,COG1999@2 NA|NA|NA S SCO1/SenC MAG.T22.3_01101 1239962.C943_00684 2.9e-91 341.3 Cytophagia yozB ko:K07152,ko:K08976 ko00000,ko03029 Bacteria 47QB2@768503,4NM5N@976,COG2322@1,COG2322@2 NA|NA|NA S Protein of unknown function (DUF420) MAG.T22.3_01102 1239962.C943_00682 0.0 2368.6 Cytophagia zraS_1 Bacteria 47JEP@768503,4NE49@976,COG5000@1,COG5000@2 NA|NA|NA T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MAG.T22.3_01103 1239962.C943_00681 0.0 2182.5 Cytophagia Bacteria 47KRW@768503,4PKQ9@976,COG3536@1,COG3536@2 NA|NA|NA S Protein conserved in bacteria MAG.T22.3_01104 1239962.C943_00680 0.0 1459.9 Cytophagia pcrA 3.6.4.12 ko:K03656,ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 47JMH@768503,4NDWN@976,COG0210@1,COG0210@2 NA|NA|NA L PFAM UvrD REP helicase MAG.T22.3_01105 1239962.C943_00678 7.4e-102 376.7 Cytophagia Bacteria 28H5J@1,2Z7I5@2,47PZX@768503,4NHK6@976 NA|NA|NA S Domain of unknown function (DUF4290) MAG.T22.3_01106 1239962.C943_00677 2.2e-243 847.8 Cytophagia murA 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 47JQ7@768503,4NDV8@976,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine MAG.T22.3_01107 1121481.AUAS01000036_gene5166 2.6e-16 90.9 Bacteroidetes Bacteria 2BWKX@1,33G81@2,4NYKR@976 NA|NA|NA MAG.T22.3_01108 1239962.C943_00676 4e-98 365.2 Cytophagia Bacteria 47JWQ@768503,4NGGZ@976,COG0457@1,COG0457@2 NA|NA|NA S TPR repeat-containing protein MAG.T22.3_01109 1239962.C943_02134 1.3e-51 208.8 Cytophagia ko:K07098 ko00000 Bacteria 47KGU@768503,4NFCH@976,COG1408@1,COG1408@2 NA|NA|NA S Calcineurin-like phosphoesterase superfamily domain MAG.T22.3_01110 1239962.C943_02134 1.5e-92 345.5 Cytophagia ko:K07098 ko00000 Bacteria 47KGU@768503,4NFCH@976,COG1408@1,COG1408@2 NA|NA|NA S Calcineurin-like phosphoesterase superfamily domain MAG.T22.3_01111 1123057.P872_08775 1.8e-13 82.4 Cytophagia Bacteria 29Z58@1,30M2Z@2,47SID@768503,4NWD0@976 NA|NA|NA S Domain of unknown function (DUF4174) MAG.T22.3_01112 866536.Belba_3190 8.3e-11 72.8 Bacteria Bacteria 28VCU@1,2ZHFI@2 NA|NA|NA MAG.T22.3_01113 1239962.C943_02137 2.6e-68 264.6 Cytophagia ko:K04767,ko:K07182 ko00000 Bacteria 47QY6@768503,4NQYH@976,COG0517@1,COG0517@2 NA|NA|NA S Domain in cystathionine beta-synthase and other proteins. MAG.T22.3_01114 525373.HMPREF0766_12343 4.8e-32 144.1 Bacteroidetes Bacteria 2E5AU@1,3302Y@2,4P4ZP@976 NA|NA|NA S Variant SH3 domain MAG.T22.3_01115 531844.FIC_01730 1.4e-21 108.6 Flavobacteriia ko:K09981 ko00000 Bacteria 1IAGB@117743,4NWSY@976,COG3809@1,COG3809@2 NA|NA|NA S Transcription factor zinc-finger MAG.T22.3_01117 1123057.P872_21305 2.8e-85 321.6 Cytophagia Bacteria 47VM2@768503,4NSGU@976,COG4337@1,COG4337@2 NA|NA|NA NU photosynthesis MAG.T22.3_01118 1121870.AUAA01000005_gene1094 1.5e-100 372.5 Chryseobacterium Bacteria 1IJ7F@117743,3HH2Q@358033,4NGWZ@976,COG2067@1,COG2067@2 NA|NA|NA I Protein of unknown function (DUF2490) MAG.T22.3_01120 694427.Palpr_0141 9.7e-31 141.0 Bacteroidetes Bacteria 2EFC2@1,3394Z@2,4NXBZ@976 NA|NA|NA MAG.T22.3_01121 926562.Oweho_0515 0.0 1516.1 Cryomorphaceae 2.1.1.72 ko:K07317 ko00000,ko01000,ko02048 Bacteria 1HYJU@117743,2PBTN@246874,4NEHR@976,COG0732@1,COG0732@2,COG0827@1,COG0827@2,COG1002@1,COG1002@2 NA|NA|NA LV PFAM Eco57I restriction endonuclease MAG.T22.3_01122 1123057.P872_12670 2.2e-22 112.8 Cytophagia Bacteria 2C9V5@1,2Z8F9@2,47S8V@768503,4NG2N@976 NA|NA|NA MAG.T22.3_01123 1237149.C900_05149 0.0 1687.9 Cytophagia 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 47MYS@768503,4NH89@976,COG4096@1,COG4096@2 NA|NA|NA L PFAM Type I restriction enzyme R protein N terminus (HSDR_N) MAG.T22.3_01124 1227266.HMPREF1551_02699 4.5e-109 401.0 Capnocytophaga Bacteria 1ERDG@1016,1I73Y@117743,28HAW@1,2Z7N4@2,4NG29@976 NA|NA|NA S KilA-N MAG.T22.3_01125 1086011.HJ01_02408 4.9e-211 740.7 Flavobacterium hsdS_2 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1HYHR@117743,2NUSP@237,4NGGB@976,COG0286@1,COG0286@2 NA|NA|NA V HsdM N-terminal domain MAG.T22.3_01126 689781.AUJX01000003_gene2971 2.3e-69 269.6 Oribacterium 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1V17Q@1239,24G4I@186801,2PSHW@265975,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain MAG.T22.3_01127 530564.Psta_3428 1.8e-100 373.6 Bacteria Bacteria COG1431@1,COG1431@2 NA|NA|NA MAG.T22.3_01128 1125700.HMPREF9195_01253 1.6e-55 223.4 Bacteria Bacteria 2BV38@1,32QG7@2 NA|NA|NA S SIR2-like domain MAG.T22.3_01129 1239962.C943_01438 1.5e-138 498.8 Cytophagia lytT ko:K02477,ko:K07705,ko:K11641 ko02020,map02020 M00492,M00494 ko00000,ko00001,ko00002,ko02022 Bacteria 47N4M@768503,4NH5N@976,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain MAG.T22.3_01130 1239962.C943_01437 3.9e-187 660.6 Cytophagia Bacteria 47PD7@768503,4NFDP@976,COG2972@1,COG2972@2 NA|NA|NA T Histidine kinase MAG.T22.3_01131 1239962.C943_01436 8.3e-117 426.4 Cytophagia lolD ko:K09810 ko02010,map02010 M00255 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 Bacteria 47KXC@768503,4NFCG@976,COG1136@1,COG1136@2 NA|NA|NA V Part of the ABC transporter complex LolCDE involved in the translocation of MAG.T22.3_01132 1239962.C943_01435 2.4e-223 781.2 Cytophagia lolC ko:K09808 ko02010,map02010 M00255 ko00000,ko00001,ko00002,ko02000 3.A.1.125 Bacteria 47MB4@768503,4NHBR@976,COG4591@1,COG4591@2 NA|NA|NA M COGs COG4591 ABC-type transport system involved in lipoprotein release permease component MAG.T22.3_01133 1239962.C943_01434 1.5e-187 662.1 Cytophagia Bacteria 47MHD@768503,4NITE@976,COG0845@1,COG0845@2 NA|NA|NA M Efflux transporter, RND family, MFP subunit MAG.T22.3_01134 1239962.C943_01433 2.9e-230 804.3 Cytophagia ko:K03287 ko00000 1.B.17 Bacteria 47KYM@768503,4NJQV@976,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein MAG.T22.3_01135 1239962.C943_01427 1.3e-221 775.4 Cytophagia MA20_26605 ko:K09003 ko00000 Bacteria 47KQY@768503,4NG24@976,COG1415@1,COG1415@2 NA|NA|NA S Protein of unknown function (DUF763) MAG.T22.3_01136 1239962.C943_01426 2e-169 601.7 Cytophagia ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 R10507 RC00083 ko00000,ko00001,ko01000 Bacteria 47TEU@768503,4NKZB@976,COG0506@1,COG0506@2 NA|NA|NA E Proline dehydrogenase MAG.T22.3_01137 1239962.C943_01424 7.1e-279 966.1 Cytophagia rpoD ko:K03086,ko:K03324 ko00000,ko02000,ko03021 2.A.58.2 Bacteria 47NEB@768503,4NHMY@976,COG1283@1,COG1283@2 NA|NA|NA P Na+/Pi-cotransporter MAG.T22.3_01138 1239962.C943_01423 2e-149 535.0 Cytophagia Bacteria 47QEW@768503,4NR8D@976,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein MAG.T22.3_01139 1239962.C943_01422 7.3e-138 496.5 Cytophagia Bacteria 47N2R@768503,4NGQY@976,COG1028@1,COG1028@2 NA|NA|NA IQ Short-chain dehydrogenase reductase SDR MAG.T22.3_01140 1239962.C943_01421 7.8e-120 436.4 Cytophagia ko:K01420,ko:K10716 ko00000,ko02000,ko03000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 Bacteria 47M33@768503,4NFIS@976,COG0664@1,COG0664@2 NA|NA|NA K PFAM Bacterial regulatory proteins, crp family MAG.T22.3_01141 1239962.C943_01420 7.3e-112 409.8 Cytophagia can GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 iNJ661.Rv3273,iSBO_1134.SBO_0115,iSbBS512_1146.SbBS512_E0119 Bacteria 47MBG@768503,4NEJT@976,COG0288@1,COG0288@2 NA|NA|NA P Reversible hydration of carbon dioxide MAG.T22.3_01142 1239962.C943_01419 0.0 1119.4 Cytophagia ko:K03321 ko00000,ko02000 2.A.53.3 Bacteria 47KT5@768503,4NFX2@976,COG0659@1,COG0659@2 NA|NA|NA U Sulfate permease family MAG.T22.3_01143 1239962.C943_01417 0.0 1701.0 Cytophagia Bacteria 47Y1Q@768503,4NDX3@976,COG1629@1,COG4771@2 NA|NA|NA P Carboxypeptidase regulatory-like domain MAG.T22.3_01144 1239962.C943_01416 2.9e-57 227.6 Cytophagia gldC Bacteria 2AGY9@1,3176X@2,47RA2@768503,4NQD4@976 NA|NA|NA S TIGRFAM Gliding motility-associated protein, GldC MAG.T22.3_01145 1239962.C943_01414 7e-27 125.9 Cytophagia yozG ko:K07727 ko00000,ko03000 Bacteria 47RJI@768503,4NUP7@976,COG3655@1,COG3655@2 NA|NA|NA K COGs COG3655 transcriptional regulator protein MAG.T22.3_01146 1239962.C943_01413 1.8e-93 348.6 Cytophagia Bacteria 2ANDI@1,31DC5@2,47PXY@768503,4NSSW@976 NA|NA|NA S Protein of unknown function (DUF2975) MAG.T22.3_01147 1239962.C943_01411 1.1e-200 705.7 Cytophagia splB Bacteria 47M4W@768503,4NE62@976,COG1533@1,COG1533@2 NA|NA|NA L SMART Elongator protein 3 MiaB NifB MAG.T22.3_01148 1121396.KB893020_gene3731 3.7e-120 438.3 Desulfobacterales ko:K07133 ko00000 Bacteria 1R3UA@1224,2MPYX@213118,2WMW9@28221,42R5M@68525,COG1373@1,COG1373@2 NA|NA|NA S AAA domain MAG.T22.3_01149 1239962.C943_01409 5.4e-111 407.1 Cytophagia Bacteria 47QPN@768503,4NRP8@976,COG0398@1,COG0398@2 NA|NA|NA S PFAM SNARE associated Golgi protein MAG.T22.3_01150 1239962.C943_01407 6.7e-220 769.6 Cytophagia metC 2.5.1.48,4.4.1.1,4.4.1.8 ko:K01739,ko:K01758,ko:K01760 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47JY2@768503,4NF0Q@976,COG0626@1,COG0626@2 NA|NA|NA E PFAM Cys Met metabolism PLP-dependent enzyme MAG.T22.3_01151 1214101.BN159_2303 5e-26 124.4 Actinobacteria Bacteria 2IIPI@201174,COG2732@1,COG2732@2 NA|NA|NA K Barstar (barnase inhibitor) MAG.T22.3_01152 1239962.C943_01406 3.5e-126 457.6 Cytophagia 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 47KFB@768503,4NFSY@976,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T22.3_01153 1239962.C943_01405 5.3e-128 463.8 Cytophagia ko:K07124 ko00000 Bacteria 47XGY@768503,4NJUU@976,COG0300@1,COG0300@2 NA|NA|NA S Enoyl-(Acyl carrier protein) reductase MAG.T22.3_01154 1239962.C943_01404 7.9e-111 406.4 Cytophagia ung2 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 47TE4@768503,4NG84@976,COG1573@1,COG1573@2 NA|NA|NA L UreE urease accessory protein, C-terminal domain MAG.T22.3_01155 1239962.C943_01403 1.4e-87 328.9 Cytophagia Bacteria 47QMT@768503,4NNZZ@976,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain MAG.T22.3_01156 929556.Solca_1974 2.8e-66 258.1 Sphingobacteriia Bacteria 1IX9F@117747,4NMVC@976,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins MAG.T22.3_01157 1454007.JAUG01000001_gene3732 6.2e-76 290.4 Bacteroidetes fic ko:K04095 ko00000,ko03036 Bacteria 4NM5F@976,COG2184@1,COG2184@2 NA|NA|NA D Fic/DOC family MAG.T22.3_01158 1239962.C943_01401 1.1e-217 762.3 Cytophagia galK 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47JY8@768503,4NE0C@976,COG0153@1,COG0153@2 NA|NA|NA G Belongs to the GHMP kinase family. GalK subfamily MAG.T22.3_01159 1239962.C943_01400 1.7e-204 718.4 Cytophagia mro 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 47KAR@768503,4NF5G@976,COG2017@1,COG2017@2 NA|NA|NA G Converts alpha-aldose to the beta-anomer MAG.T22.3_01160 1239962.C943_01399 1.4e-181 642.1 Cytophagia ko:K02529,ko:K05499 ko00000,ko03000 Bacteria 47ME3@768503,4NDW6@976,COG1609@1,COG1609@2 NA|NA|NA K PFAM Periplasmic binding protein LacI transcriptional regulator MAG.T22.3_01161 1239962.C943_01398 2.3e-184 651.4 Cytophagia ywaD Bacteria 47KMC@768503,4NG2A@976,COG2234@1,COG2234@2 NA|NA|NA S PFAM Peptidase family M28 MAG.T22.3_01162 1239962.C943_01397 6e-285 986.1 Cytophagia cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 ko:K01883,ko:K15526 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECUMN_1333.ECUMN_0566,iJN746.PP_2905,iNJ661.Rv2130c Bacteria 47MAW@768503,4NE3Y@976,COG0215@1,COG0215@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family MAG.T22.3_01163 1239962.C943_01393 1.4e-33 148.3 Bacteria Bacteria COG1598@1,COG1598@2 NA|NA|NA N PFAM Uncharacterised protein family UPF0150 MAG.T22.3_01164 32057.KB217478_gene6338 3.7e-22 110.5 Nostocales Bacteria 1GAC3@1117,1HPNS@1161,COG1724@1,COG1724@2 NA|NA|NA N mRNA binding MAG.T22.3_01165 1239962.C943_03054 4.2e-29 133.3 Cytophagia gatC 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 iAF987.Gmet_0076 Bacteria 47QWQ@768503,4NV0A@976,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) MAG.T22.3_01166 1239962.C943_03053 0.0 1639.8 Cytophagia ygfZ 3.1.21.3 ko:K01153,ko:K02498 ko00000,ko01000,ko02048 Bacteria 47Y4G@768503,4PMMA@976,COG3071@1,COG3071@2 NA|NA|NA H HemY protein MAG.T22.3_01167 1239962.C943_03052 9.1e-130 469.5 Cytophagia macB ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 47KDU@768503,4NE5N@976,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter MAG.T22.3_01168 1239962.C943_03051 1.5e-97 362.1 Cytophagia yvqK GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 ko:K00798,ko:K13821 ko00250,ko00330,ko00860,ko01100,ko01110,ko01130,map00250,map00330,map00860,map01100,map01110,map01130 M00122 R00245,R00707,R00708,R01253,R01492,R04444,R04445,R05051,R05220,R07268 RC00080,RC00083,RC00216,RC00242,RC00255,RC00533 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 47P8Y@768503,4NFHQ@976,COG2096@1,COG2096@2 NA|NA|NA S PFAM Cobalamin adenosyltransferase MAG.T22.3_01169 1239962.C943_03050 2.9e-201 707.6 Cytophagia ilvE 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 iAF987.Gmet_2853,iYO844.BSU38550 Bacteria 47M72@768503,4NEJY@976,COG0115@1,COG0115@2 NA|NA|NA EH Branched-chain amino acid aminotransferase MAG.T22.3_01170 866536.Belba_2422 8.6e-37 160.2 Cytophagia Bacteria 2DVRT@1,33WX5@2,47UUW@768503,4P3E6@976 NA|NA|NA MAG.T22.3_01171 1239962.C943_03046 7.1e-181 639.8 Cytophagia prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 47KHU@768503,4NEN1@976,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA MAG.T22.3_01172 1239962.C943_03045 2.3e-207 728.0 Cytophagia Bacteria 47MD0@768503,4NE7F@976,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T22.3_01173 1239962.C943_03044 1.7e-109 402.1 Bacteria Bacteria COG3714@1,COG3714@2 NA|NA|NA S YhhN family MAG.T22.3_01174 1239962.C943_03043 3.8e-257 893.6 Cytophagia Bacteria 47JWC@768503,4NF0F@976,COG0006@1,COG0006@2 NA|NA|NA E Metallopeptidase family M24 MAG.T22.3_01175 1239962.C943_03042 1.8e-235 821.6 Cytophagia norM ko:K03327 ko00000,ko02000 2.A.66.1 Bacteria 47KYV@768503,4NEBB@976,COG0534@1,COG0534@2 NA|NA|NA V efflux protein, MATE family MAG.T22.3_01176 1239962.C943_03041 1.9e-92 345.1 Cytophagia nudF 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 Bacteria 47P7M@768503,4NMHV@976,COG0494@1,COG0494@2 NA|NA|NA L pfam nudix MAG.T22.3_01177 1239962.C943_03040 4.4e-80 303.9 Cytophagia ko:K03719 ko00000,ko03000,ko03036 Bacteria 47P8E@768503,4NMYA@976,COG1522@1,COG1522@2 NA|NA|NA K transcriptional regulator MAG.T22.3_01179 1239962.C943_03039 2.9e-221 774.2 Cytophagia Bacteria 47Y4H@768503,4PM6F@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.3_01180 1239962.C943_03038 3.2e-110 404.4 Cytophagia Bacteria 2C6AJ@1,304IU@2,47Q1B@768503,4NPQW@976 NA|NA|NA MAG.T22.3_01181 1239962.C943_03037 0.0 1212.2 Cytophagia dcp 3.4.15.5,3.4.24.70 ko:K01284,ko:K01414 ko00000,ko01000,ko01002 Bacteria 47KDS@768503,4NFYA@976,COG0339@1,COG0339@2 NA|NA|NA E PFAM Peptidase family M3 MAG.T22.3_01182 1239962.C943_03036 5.8e-269 932.9 Cytophagia ko:K12941 ko00000,ko01002 Bacteria 47N92@768503,4NEKH@976,COG1473@1,COG1473@2 NA|NA|NA S Peptidase dimerisation domain MAG.T22.3_01183 1239962.C943_03035 3.6e-177 627.5 Cytophagia fieF Bacteria 47MW1@768503,4NEID@976,COG0053@1,COG0053@2 NA|NA|NA P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family MAG.T22.3_01184 1239962.C943_03034 7e-158 563.5 Cytophagia Bacteria 47KDN@768503,4NFHZ@976,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter MAG.T22.3_01185 1239962.C943_03033 2.2e-83 315.8 Cytophagia Bacteria 47NCH@768503,4NJ1F@976,COG0457@1,COG0457@2 NA|NA|NA S PFAM Tetratricopeptide repeat MAG.T22.3_01186 1239962.C943_03032 0.0 1771.5 Cytophagia Bacteria 47KJF@768503,4NGZ6@976,COG0642@1,COG0784@1,COG0784@2,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T22.3_01187 1239962.C943_03031 5e-221 773.5 Cytophagia Bacteria 47K0B@768503,4NH24@976,COG3746@1,COG3746@2 NA|NA|NA P Phosphate-selective porin O and P MAG.T22.3_01188 1239962.C943_03030 0.0 1491.9 Cytophagia acnA 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 47KF9@768503,4NDZT@976,COG1048@1,COG1048@2 NA|NA|NA C aconitate hydratase MAG.T22.3_01189 1239962.C943_03029 5.9e-215 753.4 Cytophagia atoE ko:K02106 ko02020,map02020 ko00000,ko00001 2.A.73.1 Bacteria 47TDJ@768503,4NIRP@976,COG2031@1,COG2031@2 NA|NA|NA I Short chain fatty acid transporter MAG.T22.3_01190 1239962.C943_03027 0.0 1077.8 Cytophagia ladS ko:K20971 ko02025,map02025 ko00000,ko00001,ko01001,ko02022 Bacteria 47Y4P@768503,4PMMC@976,COG4251@1,COG4251@2 NA|NA|NA T N-terminal 7TM region of histidine kinase MAG.T22.3_01191 1239962.C943_03026 2.9e-175 621.3 Cytophagia Bacteria 47K6Q@768503,4NEEZ@976,COG1012@1,COG1012@2 NA|NA|NA C PFAM Acyl-CoA reductase (LuxC) MAG.T22.3_01192 1239962.C943_03025 1.4e-64 251.9 Cytophagia fdx1 ko:K03522,ko:K05337 ko00000,ko04147 Bacteria 47QGR@768503,4NNF9@976,COG1145@1,COG1145@2 NA|NA|NA C 4Fe-4S binding domain MAG.T22.3_01193 1189612.A33Q_3109 3.3e-47 194.1 Cytophagia Bacteria 2ASD9@1,31HSR@2,47R7K@768503,4NQ71@976 NA|NA|NA S Protein of unknown function (DUF3276) MAG.T22.3_01194 1239962.C943_03023 2.8e-183 647.9 Cytophagia GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 47KKW@768503,4NFHZ@976,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter MAG.T22.3_01195 1120965.AUBV01000001_gene3281 2.7e-181 641.3 Cytophagia ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 ko:K06942 ko00000,ko03009 Bacteria 47KXT@768503,4NF7N@976,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner MAG.T22.3_01196 866536.Belba_2398 4.3e-150 537.3 Cytophagia ko:K19091 ko00000,ko01000,ko02048 Bacteria 47MMT@768503,4NJ54@976,COG1583@1,COG1583@2 NA|NA|NA L PFAM CRISPR associated protein Cas6 MAG.T22.3_01197 1239962.C943_03019 0.0 1770.4 Cytophagia ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 47YAQ@768503,4PNA4@976,COG2133@1,COG2133@2,COG3291@1,COG3291@2,COG4654@1,COG4654@2 NA|NA|NA CG Glucose / Sorbosone dehydrogenase MAG.T22.3_01198 1239962.C943_03018 4e-104 384.0 Cytophagia Bacteria 47PVK@768503,4NM4E@976,COG3637@1,COG3637@2 NA|NA|NA M Outer membrane protein beta-barrel domain MAG.T22.3_01199 1239962.C943_03017 7.9e-210 736.1 Cytophagia msrA GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114 1.8.4.11,1.8.4.12 ko:K07304,ko:K07305,ko:K12267 ko00000,ko01000 Bacteria 47TCV@768503,4NMAJ@976,COG0225@1,COG0225@2,COG0229@1,COG0229@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine MAG.T22.3_01200 1239962.C943_03016 1.7e-69 268.5 Cytophagia Bacteria 2AMB7@1,31C6A@2,47Q46@768503,4NQ8I@976 NA|NA|NA MAG.T22.3_01201 1239962.C943_03015 2.9e-66 257.7 Cytophagia Bacteria 47QQ7@768503,4NQAK@976,COG2755@1,COG2755@2 NA|NA|NA E Stress responsive A/B Barrel Domain MAG.T22.3_01202 1239962.C943_03014 0.0 1546.2 Cytophagia penA 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 Bacteria 47N4P@768503,4NEIX@976,COG2366@1,COG2366@2 NA|NA|NA S Penicillin amidase MAG.T22.3_01203 1239962.C943_03013 5.6e-58 229.9 Cytophagia Bacteria 47RS4@768503,4NUPH@976,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain MAG.T22.3_01204 1239962.C943_03012 1.8e-40 171.4 Cytophagia Bacteria 2BZQB@1,32Y98@2,47S0R@768503,4NVDQ@976 NA|NA|NA MAG.T22.3_01205 1239962.C943_03011 5.1e-175 620.2 Cytophagia Bacteria 47N4V@768503,4NEYE@976,COG3000@1,COG3000@2 NA|NA|NA I PFAM Fatty acid hydroxylase superfamily MAG.T22.3_01207 1239962.C943_03009 1.5e-136 492.3 Cytophagia Bacteria 47S7C@768503,4NHBB@976,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein family MAG.T22.3_01211 1288963.ADIS_0512 7.8e-31 141.4 Bacteroidetes Bacteria 2E0EQ@1,32W15@2,4NTKT@976 NA|NA|NA MAG.T22.3_01213 1239962.C943_01277 0.0 1152.5 Cytophagia 2.3.1.12,3.2.1.1 ko:K00627,ko:K01176 ko00010,ko00020,ko00500,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04973,map00010,map00020,map00500,map00620,map01100,map01110,map01120,map01130,map01200,map04973 M00307 R00209,R02108,R02112,R02569,R11262 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 GH13 Bacteria 47MW8@768503,4PKNP@976,COG0508@1,COG0508@2 NA|NA|NA C Domain of Unknown Function (DUF349) MAG.T22.3_01214 1239962.C943_01276 2.5e-106 391.3 Cytophagia yqgE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K07735 ko00000,ko03000 Bacteria 47M9N@768503,4NFQA@976,COG1678@1,COG1678@2 NA|NA|NA K Belongs to the UPF0301 (AlgH) family MAG.T22.3_01215 1239962.C943_01275 2.6e-120 438.0 Cytophagia pdxH GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 Bacteria 47P7A@768503,4NFH7@976,COG0259@1,COG0259@2 NA|NA|NA H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) MAG.T22.3_01216 1239962.C943_01274 3.6e-134 484.2 Cytophagia bshB1 ko:K01463 ko00000,ko01000 Bacteria 47K51@768503,4NEDJ@976,COG2120@1,COG2120@2 NA|NA|NA S PFAM GlcNAc-PI de-N-acetylase MAG.T22.3_01217 1239962.C943_01273 1.2e-191 675.6 Cytophagia yneA GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 ko:K06194 ko00000 1.A.34.1.2 Bacteria 47KFS@768503,4NGHH@976,COG0739@1,COG0739@2,COG1388@1,COG1388@2 NA|NA|NA M PFAM Peptidase family M23 MAG.T22.3_01218 1239962.C943_01272 7.6e-177 626.3 Cytophagia trxB GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000,ko03110 iNJ661.Rv3913 Bacteria 47JQX@768503,4NEVX@976,COG0492@1,COG0492@2 NA|NA|NA C Thioredoxin reductase MAG.T22.3_01219 1239962.C943_01271 2.9e-151 541.2 Cytophagia rpoD ko:K03086 ko00000,ko03021 Bacteria 47JZ7@768503,4NEBF@976,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released MAG.T22.3_01220 1239962.C943_01270 0.0 1377.1 Cytophagia pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 47KTE@768503,4NE4Q@976,COG1185@1,COG1185@2 NA|NA|NA J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction MAG.T22.3_01221 1239962.C943_01269 2.4e-43 181.0 Cytophagia rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47R7H@768503,4NS7U@976,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome MAG.T22.3_01222 1239962.C943_01268 2.6e-279 967.6 Cytophagia ko:K07091,ko:K11720 ko02010,map02010 M00320 ko00000,ko00001,ko00002,ko02000 1.B.42.1 Bacteria 47JCU@768503,4NE8B@976,COG0795@1,COG0795@2 NA|NA|NA S Permease YjgP YjgQ family MAG.T22.3_01224 1239962.C943_01860 1.7e-63 248.4 Cytophagia Bacteria 47RCR@768503,4NSKI@976,COG4654@1,COG4654@2 NA|NA|NA C Cytochrome c, class I MAG.T22.3_01225 1239962.C943_01859 2.5e-269 934.1 Cytophagia Bacteria 47JGA@768503,4NGHN@976,COG1524@1,COG1524@2 NA|NA|NA S PFAM type I phosphodiesterase nucleotide pyrophosphatase MAG.T22.3_01226 1239962.C943_01858 3.9e-226 790.4 Cytophagia Bacteria 47MGH@768503,4NHXX@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase domain protein TIM barrel MAG.T22.3_01227 1239962.C943_01857 6.8e-212 743.0 Cytophagia aroB 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 47K3I@768503,4NHE3@976,COG0337@1,COG0337@2 NA|NA|NA E 3-dehydroquinate synthase MAG.T22.3_01228 1239962.C943_01856 2.2e-157 561.6 Cytophagia 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 47JTB@768503,4NIXM@976,COG0382@1,COG0382@2 NA|NA|NA H UbiA prenyltransferase family MAG.T22.3_01229 1239962.C943_01855 3.4e-174 617.5 Cytophagia ko:K07051 ko00000 Bacteria 47JMM@768503,4NHVD@976,COG1099@1,COG1099@2 NA|NA|NA S TatD related DNase MAG.T22.3_01230 1239962.C943_01854 1.3e-157 562.4 Cytophagia Bacteria 28JEH@1,2Z98N@2,47MQN@768503,4NJHC@976 NA|NA|NA MAG.T22.3_01232 1239962.C943_01849 1.7e-254 884.8 Cytophagia Bacteria 47XHM@768503,4NG6G@976,COG0436@1,COG0436@2 NA|NA|NA E PFAM Aminotransferase class I and II MAG.T22.3_01233 1239962.C943_01848 3e-171 607.8 Cytophagia Bacteria 28JI8@1,2Z9BM@2,47JAX@768503,4NE5E@976 NA|NA|NA S S1 P1 nuclease MAG.T22.3_01234 1239962.C943_01847 1.5e-34 151.8 Cytophagia rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47R98@768503,4NSB1@976,COG0268@1,COG0268@2 NA|NA|NA J Binds directly to 16S ribosomal RNA MAG.T22.3_01235 1239962.C943_01846 1.3e-120 439.1 Cytophagia radC ko:K03630 ko00000 Bacteria 47KTY@768503,4NFBF@976,COG2003@1,COG2003@2 NA|NA|NA E Belongs to the UPF0758 family MAG.T22.3_01236 1239962.C943_01845 3.7e-108 397.5 Cytophagia ko:K09164 ko00000 Bacteria 47Q5N@768503,4NNWJ@976,COG3358@1,COG3358@2 NA|NA|NA S Protein of unknown function (DUF1684) MAG.T22.3_01237 1239962.C943_01844 0.0 1516.5 Cytophagia pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_2160,iPC815.YPO2428 Bacteria 47JAK@768503,4NF5B@976,COG0072@1,COG0072@2,COG0073@1,COG0073@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily MAG.T22.3_01238 1189612.A33Q_1763 4.6e-29 133.7 Bacteroidetes Bacteria 2DSW7@1,33HNN@2,4NY8S@976 NA|NA|NA MAG.T22.3_01239 1239962.C943_01842 2.1e-42 177.9 Cytophagia zapA GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 ko:K09888 ko00000,ko03036 Bacteria 47S0D@768503,4NSA5@976,COG3027@1,COG3027@2 NA|NA|NA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division MAG.T22.3_01240 1239962.C943_01841 5.2e-255 886.7 Cytophagia rny ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 47KJE@768503,4NE3V@976,COG1418@1,COG1418@2 NA|NA|NA S Endoribonuclease that initiates mRNA decay MAG.T22.3_01241 1239962.C943_01839 3e-115 421.4 Cytophagia ko:K09933 ko00000,ko01002 Bacteria 47PSP@768503,4NMII@976,COG3228@1,COG3228@2 NA|NA|NA S Belongs to the MtfA family MAG.T22.3_01242 1239962.C943_01838 3.5e-225 787.3 Cytophagia Bacteria 47MGJ@768503,4NJN0@976,COG0624@1,COG0624@2 NA|NA|NA E peptidase dimerisation domain MAG.T22.3_01243 1239962.C943_01837 1.5e-135 488.8 Cytophagia trmH 2.1.1.185 ko:K03218 ko00000,ko01000,ko03009 Bacteria 47JZC@768503,4NF6H@976,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family MAG.T22.3_01244 1239962.C943_01836 7.3e-236 822.8 Cytophagia Bacteria 28H6U@1,2Z7J5@2,47JR6@768503,4NHUU@976 NA|NA|NA MAG.T22.3_01245 1239962.C943_01835 1.7e-129 468.8 Cytophagia 2.1.1.222,2.1.1.64 ko:K00568,ko:K20444 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 47JIB@768503,4NFHE@976,COG2227@1,COG2227@2 NA|NA|NA H Methionine biosynthesis protein MetW MAG.T22.3_01247 1239962.C943_01834 0.0 1954.5 Cytophagia Bacteria 47KCA@768503,4PKJX@976,COG1807@1,COG1807@2 NA|NA|NA M Protein of unknown function (DUF2723) MAG.T22.3_01248 1239962.C943_01833 8e-54 216.1 Cytophagia trxA3 ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 47R18@768503,4NS6N@976,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family MAG.T22.3_01249 1239962.C943_01832 8e-271 939.1 Cytophagia blh Bacteria 47KD4@768503,4NE2Y@976,COG0491@1,COG0491@2,COG0607@1,COG0607@2 NA|NA|NA P COGs COG0491 Zn-dependent hydrolase including glyoxylase MAG.T22.3_01250 1239962.C943_01831 3.3e-106 391.0 Cytophagia ko:K07112 ko00000 Bacteria 47NY1@768503,4NM6E@976,COG2391@1,COG2391@2 NA|NA|NA S PFAM YeeE YedE family (DUF395) MAG.T22.3_01251 1239962.C943_01830 1.1e-70 272.7 Cytophagia ko:K07112 ko00000 Bacteria 47P92@768503,4NQ9C@976,COG2391@1,COG2391@2 NA|NA|NA S PFAM YeeE YedE family (DUF395) MAG.T22.3_01252 1239962.C943_01827 1.2e-152 546.2 Cytophagia ybjJ Bacteria 47Y46@768503,4PMKU@976,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T22.3_01253 641524.ADICYQ_0517 2.6e-26 124.8 Cytophagia ko:K07075 ko00000 Bacteria 47RWY@768503,4NV8X@976,COG1669@1,COG1669@2,COG2361@1,COG2361@2 NA|NA|NA S Nucleotidyltransferase domain MAG.T22.3_01254 1239962.C943_01826 5.2e-128 463.8 Cytophagia 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 Bacteria 47PHB@768503,4NMMY@976,COG3884@1,COG3884@2 NA|NA|NA I Acyl-ACP thioesterase MAG.T22.3_01255 1239962.C943_01825 1.2e-199 702.2 Cytophagia petA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009512,GO:0009579,GO:0016491,GO:0016667,GO:0016669,GO:0032991,GO:0044424,GO:0044436,GO:0044464,GO:0050338,GO:0055114,GO:0070069 1.8.2.2 ko:K02634,ko:K19713 ko00195,ko01100,map00195,map01100 M00162 ko00000,ko00001,ko00002,ko00194,ko01000 Bacteria 47PB1@768503,4NGIH@976,COG3258@1,COG3258@2 NA|NA|NA C Cytochrome C oxidase, cbb3-type, subunit III MAG.T22.3_01256 1239962.C943_01824 1.4e-267 928.3 Cytophagia Bacteria 28JFD@1,2Z99B@2,47NU1@768503,4NFQJ@976 NA|NA|NA MAG.T22.3_01258 1239962.C943_01820 0.0 1822.8 Bacteria ko:K20274 ko02024,map02024 ko00000,ko00001,ko01002 Bacteria COG2911@1,COG2911@2,COG3420@1,COG3420@2 NA|NA|NA P alginic acid biosynthetic process MAG.T22.3_01259 1239962.C943_01819 3.4e-83 314.3 Cytophagia Bacteria 2DVJK@1,33W6D@2,47V71@768503,4P3EC@976 NA|NA|NA MAG.T22.3_01260 1239962.C943_01818 1.6e-106 392.1 Cytophagia Bacteria 2DV3B@1,33TUU@2,47US3@768503,4P2CB@976 NA|NA|NA MAG.T22.3_01261 1239962.C943_01817 1.8e-66 258.5 Cytophagia Bacteria 299TB@1,2ZWVI@2,47X2D@768503,4P837@976 NA|NA|NA MAG.T22.3_01262 1120965.AUBV01000010_gene2748 3.3e-36 158.3 Cytophagia Bacteria 2C1BA@1,33WFG@2,47V4C@768503,4P36X@976 NA|NA|NA S Domain of unknown function (DUF4402) MAG.T22.3_01263 1239962.C943_01814 1.3e-148 532.3 Cytophagia 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 47UHZ@768503,4PAU2@976,COG3121@1,COG3121@2 NA|NA|NA NU Chaperone MAG.T22.3_01264 1239962.C943_01813 0.0 1725.3 Cytophagia htrE ko:K07347 ko05133,map05133 ko00000,ko00001,ko02000,ko02035,ko02044 1.B.11.3 Bacteria 47UEC@768503,4NFPY@976,COG3188@1,COG3188@2 NA|NA|NA NU usher protein MAG.T22.3_01265 1123057.P872_18580 1.6e-121 442.6 Cytophagia ldhA 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 47KBU@768503,4NF1R@976,COG1052@1,COG1052@2 NA|NA|NA CH D-isomer specific 2-hydroxyacid dehydrogenase MAG.T22.3_01266 1239962.C943_01811 0.0 1367.4 Cytophagia prlC 3.4.15.5,3.4.24.70 ko:K01284,ko:K01414 ko00000,ko01000,ko01002 Bacteria 47KDS@768503,4NFYA@976,COG0339@1,COG0339@2 NA|NA|NA E PFAM Peptidase family M3 MAG.T22.3_01267 1239962.C943_01809 1.3e-65 255.8 Cytophagia Bacteria 47QE6@768503,4NQ5T@976,COG1846@1,COG1846@2 NA|NA|NA K transcriptional regulator MAG.T22.3_01268 1239962.C943_01808 8.9e-82 309.7 Cytophagia Bacteria 47P9R@768503,4NNMD@976,COG2353@1,COG2353@2 NA|NA|NA S Belongs to the UPF0312 family MAG.T22.3_01269 1239962.C943_01807 5e-176 623.6 Cytophagia mhqO ko:K15975 ko00000 Bacteria 47KJP@768503,4NGE0@976,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MAG.T22.3_01270 1239962.C943_01806 2.6e-101 374.8 Cytophagia ko:K06999,ko:K15975 ko00000 Bacteria 47PPZ@768503,4NF4I@976,COG0400@1,COG0400@2 NA|NA|NA S Phospholipase/Carboxylesterase MAG.T22.3_01271 1239962.C943_01805 1.2e-115 422.5 Cytophagia Bacteria 47J8W@768503,4NNS3@976,COG5587@1,COG5587@2 NA|NA|NA S TIGRFAM TIGR02453 family protein MAG.T22.3_01275 1239962.C943_01777 2.7e-195 688.0 Cytophagia ko:K07133 ko00000 Bacteria 47P2P@768503,4NE3E@976,COG1373@1,COG1373@2 NA|NA|NA S AAA domain MAG.T22.3_01276 1288963.ADIS_4839 5.9e-15 87.0 Cytophagia ko:K06218 ko00000,ko02048 Bacteria 47R8J@768503,4NW0W@976,COG2026@1,COG2026@2 NA|NA|NA DJ RelE toxin of RelE / RelB toxin-antitoxin system MAG.T22.3_01277 886379.AEWI01000086_gene1630 5.1e-07 60.1 Bacteroidetes Bacteria 28T5Q@1,2ZFEK@2,4P6S7@976 NA|NA|NA MAG.T22.3_01278 1239962.C943_01803 2e-45 188.0 Cytophagia Bacteria 2EFW8@1,339NG@2,47W8Q@768503,4NXQM@976 NA|NA|NA MAG.T22.3_01279 1123057.P872_05850 1.1e-32 146.4 Cytophagia Bacteria 2DWM5@1,340Z9@2,47VB1@768503,4P45B@976 NA|NA|NA MAG.T22.3_01280 1239962.C943_01801 1.4e-84 318.9 Cytophagia tdcF Bacteria 47PYP@768503,4NPUF@976,COG0251@1,COG0251@2 NA|NA|NA J Endoribonuclease L-PSP MAG.T22.3_01281 1239962.C943_01800 1.3e-204 718.8 Cytophagia amyA 3.2.1.1 ko:K07405 ko00500,ko01100,map00500,map01100 R02108,R02112,R11262 ko00000,ko00001,ko01000 GH57 Bacteria 47P2J@768503,4NFXW@976,COG1449@1,COG1449@2 NA|NA|NA G Belongs to the glycosyl hydrolase 57 family MAG.T22.3_01282 1239962.C943_01799 3.2e-247 860.5 Cytophagia GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.11,2.4.1.18 ko:K16149,ko:K16150 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R00292,R02110 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 GH57,GT4 Bacteria 47JA2@768503,4PKP8@976,COG0297@1,COG0297@2 NA|NA|NA G Starch synthase catalytic domain MAG.T22.3_01283 1239962.C943_01798 0.0 1315.8 Cytophagia glgX Bacteria 47M96@768503,4NF09@976,COG3408@1,COG3408@2 NA|NA|NA G Glycogen debranching enzyme MAG.T22.3_01285 1239962.C943_01796 2.1e-244 851.3 Cytophagia pyrC 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 47JPG@768503,4NE3T@976,COG0044@1,COG0044@2 NA|NA|NA F TIGRFAM dihydroorotase, multifunctional complex type MAG.T22.3_01286 1239962.C943_01795 1e-246 859.0 Cytophagia 3.6.4.13 ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 47M9H@768503,4NEVI@976,COG0513@1,COG0513@2 NA|NA|NA L Belongs to the DEAD box helicase family MAG.T22.3_01287 1239962.C943_01794 1.1e-89 335.9 Cytophagia Bacteria 28NN4@1,2ZBNJ@2,47PGF@768503,4NMVI@976 NA|NA|NA MAG.T22.3_01288 1239962.C943_01793 1.4e-122 445.7 Cytophagia Bacteria 47NRV@768503,4NKBS@976,COG4912@1,COG4912@2 NA|NA|NA L DNA alkylation repair enzyme MAG.T22.3_01290 1239962.C943_01792 1.8e-102 378.6 Bacteroidetes ko:K02282 ko00000,ko02035,ko02044 Bacteria 4NN0B@976,COG2197@1,COG2197@2 NA|NA|NA T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain MAG.T22.3_01291 866536.Belba_1529 4.1e-22 110.5 Cytophagia Bacteria 2DYM1@1,34AAJ@2,47VRQ@768503,4P5W6@976 NA|NA|NA MAG.T22.3_01292 1239962.C943_01790 3e-143 514.6 Cytophagia udp 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 Bacteria 47K9N@768503,4NG5S@976,COG2820@1,COG2820@2 NA|NA|NA F PFAM Phosphorylase superfamily MAG.T22.3_01293 1239962.C943_01789 2e-199 701.4 Cytophagia yceA ko:K07146 ko00000 Bacteria 47JH6@768503,4NEG6@976,COG1054@1,COG1054@2 NA|NA|NA S Belongs to the UPF0176 family MAG.T22.3_01294 1239962.C943_01788 1e-85 323.2 Cytophagia Bacteria 47PJQ@768503,4NNTF@976,COG0110@1,COG0110@2 NA|NA|NA S sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family MAG.T22.3_01295 1239962.C943_01787 2.9e-243 847.4 Cytophagia Bacteria 28HQ3@1,2Z7XW@2,47KPJ@768503,4NF9H@976 NA|NA|NA S Protein of unknown function (DUF2851) MAG.T22.3_01296 1239962.C943_01786 4.5e-149 533.9 Cytophagia pyrF GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS17585 Bacteria 47JHC@768503,4NE12@976,COG0284@1,COG0284@2 NA|NA|NA F Orotidine 5''-phosphate decarboxylase MAG.T22.3_01297 1239962.C943_01785 1.9e-118 431.8 Cytophagia ydcC Bacteria 47PRT@768503,4NFGN@976,COG2834@1,COG2834@2 NA|NA|NA M PFAM Outer membrane lipoprotein carrier protein LolA MAG.T22.3_01298 1239962.C943_01784 0.0 1455.3 Cytophagia ftsK ko:K03466 ko00000,ko03036 3.A.12 Bacteria 47JI0@768503,4NE86@976,COG1674@1,COG1674@2 NA|NA|NA D DNA segregation ATPase FtsK SpoIIIE MAG.T22.3_01299 1239962.C943_01782 3.7e-188 664.1 Cytophagia pyrD GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 ko:K00254,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01868,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 iEC042_1314.EC042_1029,iECIAI39_1322.ECIAI39_2202,iECUMN_1333.ECUMN_1134,iEcSMS35_1347.EcSMS35_2174,iPC815.YPO1415,iYL1228.KPN_00974 Bacteria 47KYQ@768503,4NDVB@976,COG0167@1,COG0167@2 NA|NA|NA F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor MAG.T22.3_01300 1239962.C943_01776 7e-130 469.9 Cytophagia rluF GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.21,5.4.99.22 ko:K06178,ko:K06182,ko:K06183 ko00000,ko01000,ko03009 Bacteria 47JSA@768503,4NFE1@976,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family MAG.T22.3_01301 1239962.C943_01775 1.8e-167 595.1 Cytophagia xerC ko:K04763 ko00000,ko03036 Bacteria 47JU5@768503,4NE0E@976,COG4974@1,COG4974@2 NA|NA|NA D Tyrosine recombinase XerC MAG.T22.3_01302 1239962.C943_01773 4.5e-194 683.7 Cytophagia 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 47J9K@768503,4PKNG@976,COG0075@1,COG0075@2 NA|NA|NA E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine MAG.T22.3_01303 1239962.C943_01772 6.7e-91 340.1 Cytophagia marC ko:K05595 ko00000,ko02000 2.A.95.1 Bacteria 47PA2@768503,4NG94@976,COG2095@1,COG2095@2 NA|NA|NA U PFAM MarC family integral membrane protein MAG.T22.3_01304 1239962.C943_01771 4e-86 323.9 Cytophagia rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 47PXE@768503,4NNQX@976,COG0328@1,COG0328@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids MAG.T22.3_01305 1239962.C943_01770 6.7e-109 400.2 Cytophagia yfiC GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.223,2.1.1.72 ko:K00571,ko:K15460 ko00000,ko01000,ko02048,ko03016 Bacteria 47QFW@768503,4NG1X@976,COG4123@1,COG4123@2 NA|NA|NA J Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) MAG.T22.3_01306 1123057.P872_22580 1.2e-128 466.8 Cytophagia Bacteria 47U5I@768503,4P0PS@976,COG3055@1,COG3055@2 NA|NA|NA S IPT/TIG domain MAG.T22.3_01307 1239962.C943_01768 0.0 1591.6 Cytophagia Bacteria 47N3A@768503,4NF4B@976,COG1629@1,COG4771@2 NA|NA|NA P Carboxypeptidase regulatory-like domain MAG.T22.3_01308 1239962.C943_01767 1e-198 699.1 Cytophagia Bacteria 28I8D@1,2ZBHJ@2,47KUP@768503,4NHI9@976 NA|NA|NA S Domain of unknown function (DUF4249) MAG.T22.3_01309 1239962.C943_01765 4.4e-258 896.7 Cytophagia ko:K07263 ko00000,ko01000,ko01002 Bacteria 47M1B@768503,4NEDZ@976,COG0612@1,COG0612@2 NA|NA|NA S PFAM Peptidase M16 inactive domain MAG.T22.3_01310 1239962.C943_01764 0.0 1295.8 Cytophagia Bacteria 47M2G@768503,4NEPT@976,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 inactive domain MAG.T22.3_01311 1239962.C943_01762 1.6e-105 389.0 Cytophagia Bacteria 47WHZ@768503,4P71F@976,COG0612@1,COG0612@2 NA|NA|NA S Peptidase, M16 MAG.T22.3_01312 1239962.C943_01761 1.1e-58 232.6 Cytophagia catD ko:K15977 ko00000 Bacteria 47W87@768503,4NP94@976,COG2259@1,COG2259@2 NA|NA|NA S DoxX MAG.T22.3_01313 1239962.C943_01759 3.1e-258 897.5 Cytophagia Bacteria 47JI8@768503,4NGTY@976,COG3975@1,COG3975@2 NA|NA|NA S protease with the C-terminal PDZ domain MAG.T22.3_01314 1239962.C943_01757 1.3e-52 212.2 Cytophagia rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 ko00000,ko01000,ko03016 Bacteria 47S3A@768503,4NUMM@976,COG0594@1,COG0594@2 NA|NA|NA J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme MAG.T22.3_01315 1239962.C943_01756 1.3e-299 1035.0 Cytophagia prc 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 47JTG@768503,4NDWU@976,COG0793@1,COG0793@2 NA|NA|NA M Belongs to the peptidase S41A family MAG.T22.3_01316 1239962.C943_01755 6.4e-88 330.5 Cytophagia yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 ko:K14742 ko00000,ko03016 Bacteria 47NST@768503,4NDUR@976,COG1214@1,COG1214@2 NA|NA|NA O TIGRFAM universal bacterial protein YeaZ MAG.T22.3_01317 1239962.C943_01754 1.4e-81 308.9 Cytophagia Bacteria 28NIX@1,2ZBK6@2,47MBS@768503,4NMEI@976 NA|NA|NA S Protein of unknown function (DUF2480) MAG.T22.3_01318 1239962.C943_00056 1e-82 312.8 Cytophagia 2.7.13.3 ko:K02482 ko00000,ko01000,ko01001,ko02022 Bacteria 47N98@768503,4NEJX@976,COG3292@1,COG3292@2,COG4191@1,COG4191@2 NA|NA|NA T Y_Y_Y domain MAG.T22.3_01319 1189612.A33Q_2378 2e-83 316.2 Cytophagia Bacteria 47MAD@768503,4NGTB@976,COG3287@1,COG3287@2 NA|NA|NA S FIST_C MAG.T22.3_01320 1189619.pgond44_14053 4.2e-145 521.2 Flavobacteriia Bacteria 1HX3X@117743,4NGTB@976,COG3287@1,COG3287@2 NA|NA|NA T FIST N domain MAG.T22.3_01321 1189612.A33Q_2376 1.8e-129 469.2 Bacteroidetes Bacteria 4NEJX@976,COG4191@1,COG4191@2 NA|NA|NA T Histidine kinase MAG.T22.3_01322 1239962.C943_00056 0.0 1622.8 Cytophagia 2.7.13.3 ko:K02482 ko00000,ko01000,ko01001,ko02022 Bacteria 47N98@768503,4NEJX@976,COG3292@1,COG3292@2,COG4191@1,COG4191@2 NA|NA|NA T Y_Y_Y domain MAG.T22.3_01323 1239962.C943_00054 0.0 1215.3 Cytophagia Bacteria 47KW1@768503,4NEJX@976,COG4191@1,COG4191@2 NA|NA|NA T Histidine kinase MAG.T22.3_01324 1239962.C943_00053 2.9e-157 561.2 Cytophagia ppx 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 47KHJ@768503,4NEI0@976,COG0248@1,COG0248@2 NA|NA|NA FP PFAM Ppx GppA phosphatase MAG.T22.3_01325 1239962.C943_00052 2.2e-31 141.4 Cytophagia ko:K00389 ko00000 Bacteria 47SRQ@768503,4NZ1E@976,COG2149@1,COG2149@2 NA|NA|NA S Domain of unknown function (DUF202) MAG.T22.3_01326 1239962.C943_00051 5.4e-217 760.0 Cytophagia rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K07444,ko:K12297 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 47MFH@768503,4NFJM@976,COG0116@1,COG0116@2 NA|NA|NA L Belongs to the methyltransferase superfamily MAG.T22.3_01327 1239962.C943_00050 0.0 1357.8 Cytophagia 3.4.17.21 ko:K01301 ko00000,ko01000,ko01002 Bacteria 47MK3@768503,4NI5W@976,COG2234@1,COG2234@2 NA|NA|NA S glutamate carboxypeptidase MAG.T22.3_01328 1239962.C943_00049 1.9e-130 471.9 Cytophagia 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 47PE7@768503,4PMRX@976,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain MAG.T22.3_01329 1239962.C943_00048 3.9e-185 654.1 Bacteroidetes Bacteria 4NS0A@976,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter MAG.T22.3_01333 1121904.ARBP01000005_gene4813 4.4e-15 87.4 Cytophagia Bacteria 2E8WY@1,33373@2,47RXW@768503,4NV40@976 NA|NA|NA MAG.T22.3_01334 1121904.ARBP01000004_gene1024 9.3e-53 213.8 Cytophagia quiP 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 Bacteria 47JRC@768503,4NEIX@976,COG2366@1,COG2366@2 NA|NA|NA S PFAM peptidase S45 penicillin amidase MAG.T22.3_01335 1239962.C943_03130 2.5e-124 451.4 Cytophagia braZ ko:K09792 ko00000 Bacteria 47QDS@768503,4NF84@976,COG2836@1,COG2836@2 NA|NA|NA S Cytochrome C biogenesis protein transmembrane region MAG.T22.3_01336 1239962.C943_03131 2.3e-72 278.1 Cytophagia ccoH ko:K09926 ko00000 Bacteria 47RV1@768503,4PPZ3@976,COG3198@1,COG3198@2 NA|NA|NA S FixH MAG.T22.3_01337 1239962.C943_03132 5.1e-262 909.8 Cytophagia ccoG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 47KT1@768503,4NFDN@976,COG0348@1,COG0348@2 NA|NA|NA C TIGRFAM cytochrome c oxidase accessory protein MAG.T22.3_01338 1239962.C943_03133 3.2e-154 551.2 Cytophagia ccoP ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002 3.D.4.3 Bacteria 47PY8@768503,4NFMJ@976,COG2010@1,COG2010@2 NA|NA|NA C TIGRFAM cytochrome c oxidase, cbb3-type, subunit III MAG.T22.3_01339 866536.Belba_3769 3.3e-23 113.6 Cytophagia Bacteria 47SV3@768503,4NXV9@976,COG2010@1,COG2010@2 NA|NA|NA C Cbb3-type cytochrome oxidase component FixQ MAG.T22.3_01340 1239962.C943_03135 0.0 1409.0 Cytophagia ccoO GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 ko:K00404,ko:K00405,ko:K15862 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iIT341.HP0144,iIT341.HP0145 Bacteria 47MI5@768503,4NEGM@976,COG2993@1,COG2993@2,COG3278@1,COG3278@2 NA|NA|NA C Belongs to the heme-copper respiratory oxidase family MAG.T22.3_01341 1239962.C943_03136 1.3e-21 108.6 Bacteria ccoS Bacteria COG3197@1,COG3197@2 NA|NA|NA P Cytochrome oxidase maturation protein MAG.T22.3_01342 1239962.C943_03137 0.0 1545.4 Cytophagia fixI GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 47N4X@768503,4NEI1@976,COG2217@1,COG2217@2,COG2608@1,COG2608@2 NA|NA|NA P ATPase, P-type (transporting), HAD superfamily, subfamily IC MAG.T22.3_01343 1239962.C943_03138 1.3e-130 472.2 Cytophagia Bacteria 28Z0D@1,2ZKT1@2,47PM0@768503,4NMS7@976 NA|NA|NA MAG.T22.3_01344 1239962.C943_03139 1.5e-126 458.8 Cytophagia Bacteria 2DB9P@1,2Z7Y1@2,47M0R@768503,4NHQN@976 NA|NA|NA S Domain of Unknown Function (DUF1080) MAG.T22.3_01348 1239962.C943_03140 6.1e-154 550.1 Cytophagia waaM 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 47MHM@768503,4NGQU@976,COG1560@1,COG1560@2 NA|NA|NA M Lipid A biosynthesis acyltransferase MAG.T22.3_01349 1239962.C943_03141 5.8e-106 390.2 Cytophagia sigH GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 ko:K03088 ko00000,ko03021 Bacteria 47JFG@768503,4NEFR@976,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T22.3_01350 1239962.C943_03142 3.6e-41 173.7 Cytophagia Bacteria 2EK82@1,33DYE@2,47SMK@768503,4NYF0@976 NA|NA|NA MAG.T22.3_01351 1239962.C943_03143 1.7e-102 378.6 Cytophagia gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 ko:K00942,ko:K01591 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00050,M00051 R00332,R00965,R02090 RC00002,RC00409 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2813,iIT341.HP0321,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Bacteria 47M4J@768503,4NEDG@976,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP MAG.T22.3_01352 1239962.C943_03144 1.4e-98 365.5 Cytophagia nadD 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 47JKF@768503,4NFQI@976,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) MAG.T22.3_01355 1239962.C943_03146 6.3e-144 516.9 Cytophagia Bacteria 47R07@768503,4NGPY@976,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain MAG.T22.3_01356 1239962.C943_03147 1.9e-134 485.3 Cytophagia 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 47M0E@768503,4NF20@976,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family MAG.T22.3_01357 1239962.C943_03148 2.8e-202 711.1 Cytophagia dnaN 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 47M1J@768503,4NESB@976,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria MAG.T22.3_01358 1239962.C943_03149 1.8e-309 1067.8 Cytophagia gldG ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 47JZF@768503,4NF62@976,COG3225@1,COG3225@2 NA|NA|NA N ABC transporter substrate-binding component GldG MAG.T22.3_01359 1239962.C943_03150 3.2e-119 434.5 Cytophagia gldF ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 47KPQ@768503,4NG5G@976,COG1277@1,COG1277@2 NA|NA|NA S TIGRFAM Gliding motility-associated ABC transporter permease protein GldF MAG.T22.3_01360 1239962.C943_03151 1.8e-143 515.4 Cytophagia gldA 3.6.3.7 ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 M00253,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.115 Bacteria 47KF6@768503,4NEH0@976,COG1131@1,COG1131@2 NA|NA|NA V TIGRFAM Gliding motility-associated ABC transporter ATP-binding subunit GldA MAG.T22.3_01361 1239962.C943_03152 3e-96 358.2 Bacteroidetes Bacteria 2DWQN@1,341FB@2,4P4AQ@976 NA|NA|NA S Protein of unknown function (DUF3575) MAG.T22.3_01362 1239962.C943_03154 0.0 1666.7 Cytophagia Bacteria 47M4H@768503,4NFPN@976,COG1470@1,COG1470@2 NA|NA|NA S CarboxypepD_reg-like domain MAG.T22.3_01363 1239962.C943_03155 0.0 1735.3 Cytophagia Bacteria 47XIS@768503,4NQGN@976,COG1629@1,COG1629@2 NA|NA|NA P Carboxypeptidase regulatory-like domain MAG.T22.3_01364 1239962.C943_03156 0.0 1571.2 Bacteroidetes Bacteria 4NF4B@976,COG1629@1,COG4771@2 NA|NA|NA P TonB-dependent receptor MAG.T22.3_01365 1239962.C943_03157 2.8e-175 621.3 Cytophagia Bacteria 28I8D@1,32Q7B@2,47W40@768503,4PBP6@976 NA|NA|NA S Domain of unknown function (DUF4249) MAG.T22.3_01366 1239962.C943_03158 1.6e-113 415.6 Cytophagia Bacteria 2DZT8@1,32VIB@2,47TQP@768503,4NRNI@976 NA|NA|NA MAG.T22.3_01367 1239962.C943_03159 0.0 1181.4 Cytophagia dnaK GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 47JCZ@768503,4NERF@976,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein MAG.T22.3_01368 1239962.C943_03160 1.5e-64 251.9 Cytophagia groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 ko:K04078 ko00000,ko03029,ko03110 Bacteria 47Q9W@768503,4NRE1@976,COG0234@1,COG0234@2 NA|NA|NA O Chaperonin 10 Kd subunit MAG.T22.3_01369 1239962.C943_03163 4.5e-24 117.1 Bacteroidetes Bacteria 2E3WE@1,32YTJ@2,4NX1R@976 NA|NA|NA MAG.T22.3_01370 1239962.C943_03164 3.8e-210 737.3 Cytophagia Bacteria 28IEX@1,2Z8GX@2,47NK3@768503,4NGBY@976 NA|NA|NA S Putative beta-barrel porin-2, OmpL-like. bbp2 MAG.T22.3_01371 1239962.C943_03165 8.4e-243 845.9 Bacteroidetes amtB ko:K03320 ko00000,ko02000 1.A.11 iJN678.amt2 Bacteria 4NDV2@976,COG0004@1,COG0004@2 NA|NA|NA P Ammonium Transporter MAG.T22.3_01372 1239962.C943_03167 2.1e-174 618.2 Cytophagia hemB GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47K34@768503,4NFW6@976,COG0113@1,COG0113@2 NA|NA|NA H Belongs to the ALAD family MAG.T22.3_01373 1239962.C943_03168 1.8e-234 818.1 Cytophagia Bacteria 47MFQ@768503,4NG5Z@976,COG3746@1,COG3746@2 NA|NA|NA P PFAM Phosphate-selective porin O and P MAG.T22.3_01374 1189612.A33Q_0578 7e-89 333.6 Cytophagia pgmB 5.4.2.6 ko:K01838 ko00500,map00500 R02728,R11310 RC00408 ko00000,ko00001,ko01000 Bacteria 47KFT@768503,4NHHK@976,COG0637@1,COG0637@2 NA|NA|NA S TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED MAG.T22.3_01375 1239962.C943_03172 1.8e-245 854.7 Cytophagia rocD GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 ko:K00819,ko:K00821 ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00667,R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 iYO844.BSU40340 Bacteria 47K80@768503,4NE93@976,COG4992@1,COG4992@2 NA|NA|NA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family MAG.T22.3_01377 1239962.C943_03174 1.4e-37 161.8 Cytophagia rpmB GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47R5P@768503,4NS7Q@976,COG0227@1,COG0227@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL28 family MAG.T22.3_01378 1048983.EL17_13520 1.9e-23 114.4 Cytophagia rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47S6V@768503,4NURM@976,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family MAG.T22.3_01379 866536.Belba_0216 8.2e-17 92.0 Cytophagia Bacteria 2E359@1,32P2Z@2,47SNB@768503,4NWAD@976 NA|NA|NA S Domain of unknown function (DUF4295) MAG.T22.3_01380 1239962.C943_03177 2.4e-170 604.7 Cytophagia ftsY ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 47JVI@768503,4NE9Z@976,COG0552@1,COG0552@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) MAG.T22.3_01381 1239962.C943_03179 5.6e-98 363.6 Bacteria Bacteria 2DRXB@1,33DI0@2 NA|NA|NA MAG.T22.3_01382 1239962.C943_03180 1.6e-132 478.8 Cytophagia ybfF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0016790,GO:0044424,GO:0044444,GO:0044464,GO:0052689 ko:K01175 ko00000,ko01000 Bacteria 47JB4@768503,4NDZI@976,COG0596@1,COG0596@2 NA|NA|NA S Serine aminopeptidase, S33 MAG.T22.3_01383 1340493.JNIF01000003_gene3831 1.3e-12 79.3 Bacteria Bacteria COG0520@1,COG0520@2 NA|NA|NA E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine MAG.T22.3_01384 1239962.C943_03182 4.3e-153 547.4 Cytophagia fjo11 Bacteria 47MRR@768503,4NEHX@976,COG0697@1,COG0697@2 NA|NA|NA EG PFAM EamA-like transporter family MAG.T22.3_01385 1239962.C943_03183 1e-184 652.5 Cytophagia dus ko:K05540 ko00000,ko01000,ko03016 Bacteria 47JGV@768503,4NEN4@976,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines MAG.T22.3_01386 1239962.C943_03184 2.7e-158 564.7 Cytophagia ko:K07052 ko00000 Bacteria 47JZ8@768503,4NHE1@976,COG1266@1,COG1266@2 NA|NA|NA S PFAM CAAX amino terminal protease family MAG.T22.3_01387 1239962.C943_03186 1e-140 506.1 Cytophagia cdsA 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 47KPM@768503,4NIPM@976,COG4589@1,COG4589@2 NA|NA|NA S Belongs to the CDS family MAG.T22.3_01388 1239962.C943_03187 4.1e-242 843.6 Cytophagia gdhA 1.4.1.3,1.4.1.4 ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47K4Z@768503,4NEBH@976,COG0334@1,COG0334@2 NA|NA|NA E Belongs to the Glu Leu Phe Val dehydrogenases family MAG.T22.3_01389 1239962.C943_03188 6.4e-112 410.2 Cytophagia psd 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 47MWN@768503,4NFU1@976,COG0688@1,COG0688@2 NA|NA|NA I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) MAG.T22.3_01390 1239962.C943_03189 3.3e-72 277.7 Cytophagia Bacteria 2BVEI@1,32QU5@2,47QRK@768503,4NRPR@976 NA|NA|NA MAG.T22.3_01391 1123057.P872_17880 1e-34 152.9 Cytophagia Bacteria 2DVWZ@1,33XI1@2,47V4X@768503,4P3PI@976 NA|NA|NA MAG.T22.3_01392 1239962.C943_03191 1.2e-103 382.5 Cytophagia Bacteria 47KVV@768503,4NEXS@976,COG2860@1,COG2860@2 NA|NA|NA S UPF0126 domain MAG.T22.3_01393 1239962.C943_03192 0.0 1383.2 Cytophagia Bacteria 47J8T@768503,4NGBJ@976,COG4206@1,COG4206@2 NA|NA|NA H TonB-dependent Receptor Plug Domain MAG.T22.3_01394 1239962.C943_03193 3e-87 328.2 Cytophagia Bacteria 2C9AB@1,2ZB91@2,47M3Q@768503,4NKQ3@976 NA|NA|NA MAG.T22.3_01395 744872.Spica_2281 2.6e-15 89.0 Spirochaetes Bacteria 2C9A5@1,2J81Q@203691,301UA@2 NA|NA|NA MAG.T22.3_01396 1239962.C943_03195 3.8e-84 317.4 Bacteroidetes Bacteria 4NMS3@976,COG5395@1,COG5395@2 NA|NA|NA S membrane protein (DUF2306) MAG.T22.3_01397 926560.KE387025_gene4043 3.7e-10 70.9 Bacteria Bacteria 2EG8Z@1,33A0S@2 NA|NA|NA MAG.T22.3_01398 1239962.C943_03197 3e-177 627.9 Cytophagia Bacteria 47N4N@768503,4NFDP@976,COG2972@1,COG2972@2 NA|NA|NA T PFAM histidine kinase internal region MAG.T22.3_01399 1239962.C943_03198 7.3e-122 443.4 Cytophagia lytT ko:K02477,ko:K07705,ko:K11641 ko02020,map02020 M00492,M00494 ko00000,ko00001,ko00002,ko02022 Bacteria 47MTX@768503,4NGBF@976,COG3279@1,COG3279@2 NA|NA|NA KT Response regulator of the LytR AlgR family MAG.T22.3_01400 1239962.C943_03199 5.5e-119 433.7 Cytophagia rsmI_1 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 47N4G@768503,4NDXE@976,COG0313@1,COG0313@2 NA|NA|NA H PFAM Tetrapyrrole (Corrin Porphyrin) Methylases MAG.T22.3_01401 1239962.C943_03200 2.1e-260 904.4 Cytophagia mltF ko:K18691 ko00000,ko01000,ko01011 Bacteria 47NX6@768503,4NHFW@976,COG4623@1,COG4623@2 NA|NA|NA M soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein MAG.T22.3_01402 1239962.C943_03201 2.7e-180 638.3 Cytophagia tolC Bacteria 47PGX@768503,4NEMI@976,COG1538@1,COG1538@2 NA|NA|NA MU PFAM Outer membrane efflux protein MAG.T22.3_01403 1239962.C943_03202 0.0 1860.9 Cytophagia bepE_4 ko:K03296,ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 Bacteria 47K8C@768503,4NDZG@976,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T22.3_01404 1239962.C943_03203 1e-185 656.0 Cytophagia ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 Bacteria 47KNA@768503,4NERP@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.3_01405 1239962.C943_03204 1.4e-144 518.8 Cytophagia Bacteria 47NNH@768503,4NEY1@976,COG0596@1,COG0596@2 NA|NA|NA S Ndr family MAG.T22.3_01406 1239962.C943_03205 0.0 1475.3 Cytophagia dpp 3.4.14.5 ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Bacteria 47KF8@768503,4NETS@976,COG0823@1,COG0823@2,COG1506@1,COG1506@2 NA|NA|NA EU Dipeptidyl peptidase IV (DPP IV) N-terminal region MAG.T22.3_01409 1239962.C943_01477 1.8e-119 435.3 Cytophagia sdhC ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 Bacteria 2CAZH@1,2Z7RU@2,47NEV@768503,4NGM5@976 NA|NA|NA S TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family MAG.T22.3_01410 1239962.C943_01478 0.0 1285.0 Cytophagia sdhA 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 47JE5@768503,4NFDU@976,COG1053@1,COG1053@2 NA|NA|NA C TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit MAG.T22.3_01411 1239962.C943_01479 1.8e-141 508.4 Cytophagia frdB 1.3.5.1,1.3.5.4 ko:K00240,ko:K00245 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2395 Bacteria 47KHR@768503,4NFR3@976,COG0479@1,COG0479@2 NA|NA|NA C TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein MAG.T22.3_01413 1288963.ADIS_1909 1.2e-50 206.1 Bacteroidetes Bacteria 2E72Y@1,331MI@2,4NVQ4@976 NA|NA|NA MAG.T22.3_01414 1120966.AUBU01000009_gene2690 3e-68 264.6 Bacteria Bacteria COG1609@1,COG1609@2 NA|NA|NA K purine nucleotide biosynthetic process MAG.T22.3_01415 1120966.AUBU01000009_gene2689 2.5e-79 301.6 Cytophagia Bacteria 2DZM5@1,32VDM@2,47RZ3@768503,4NW3Z@976 NA|NA|NA MAG.T22.3_01416 1120966.AUBU01000009_gene2688 1.7e-140 506.5 Bacteroidetes 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 4NK11@976,COG0732@1,COG0732@2 NA|NA|NA V PFAM Type I restriction modification DNA specificity domain MAG.T22.3_01417 1120966.AUBU01000009_gene2687 1.5e-277 961.4 Cytophagia hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 47JUM@768503,4NGGB@976,COG0286@1,COG0286@2 NA|NA|NA V PFAM N-6 DNA methylase MAG.T22.3_01418 153721.MYP_1692 3.3e-56 224.6 Cytophagia ko:K07491 ko00000 Bacteria 47Q23@768503,4NQTF@976,COG1943@1,COG1943@2 NA|NA|NA L transposase IS200-family protein MAG.T22.3_01419 1120966.AUBU01000009_gene2685 0.0 1410.6 Cytophagia hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 47MYS@768503,4NH89@976,COG4096@1,COG4096@2 NA|NA|NA L PFAM Type I restriction enzyme R protein N terminus (HSDR_N) MAG.T22.3_01420 1239962.C943_01480 2.8e-288 997.3 Cytophagia ko:K02305 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002 3.D.4.10 Bacteria 47TS8@768503,4NHGP@976,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA CG Glucose / Sorbosone dehydrogenase MAG.T22.3_01421 866536.Belba_2728 3.5e-10 71.6 Cytophagia Bacteria 2E6GM@1,3313V@2,47W8D@768503,4NT39@976 NA|NA|NA MAG.T22.3_01422 1239962.C943_01482 0.0 1457.6 Cytophagia Bacteria 47XXQ@768503,4PKNV@976,COG4206@1,COG4206@2 NA|NA|NA H Outer membrane protein beta-barrel family MAG.T22.3_01423 1239962.C943_01486 4.4e-166 590.5 Cytophagia Bacteria 47KBW@768503,4NEHD@976,COG2207@1,COG2207@2 NA|NA|NA K Transcriptional regulator, AraC family MAG.T22.3_01424 1239962.C943_01487 1.1e-155 555.8 Cytophagia Bacteria 2CJWE@1,30Y1E@2,47QV6@768503,4NNQQ@976 NA|NA|NA MAG.T22.3_01425 1239962.C943_01488 9.7e-289 998.8 Cytophagia hexA 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 GH20 Bacteria 47K79@768503,4NE08@976,COG3525@1,COG3525@2 NA|NA|NA G PFAM Glycoside hydrolase, family 20, catalytic core MAG.T22.3_01426 1239962.C943_01491 8.2e-295 1018.8 Cytophagia Bacteria 47JNX@768503,4NEN5@976,COG0673@1,COG0673@2 NA|NA|NA S PFAM Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.3_01427 1239962.C943_01492 1.9e-115 421.8 Bacteroidetes cpcT GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0017006,GO:0017007,GO:0017009,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 ko:K05383 ko00196,ko01100,map00196,map01100 ko00000,ko00001,ko00194 Bacteria 2CCNY@1,2Z877@2,4NR3D@976 NA|NA|NA E CpeT/CpcT family (DUF1001) MAG.T22.3_01428 1239962.C943_01493 4.7e-233 813.5 Cytophagia xseA 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 47NEW@768503,4NE64@976,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides MAG.T22.3_01429 1239962.C943_01494 2.2e-25 120.9 Cytophagia xseB 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 47SQS@768503,4PA4Q@976,COG1722@1,COG1722@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides MAG.T22.3_01430 1123057.P872_08685 7.1e-44 184.1 Cytophagia Bacteria 2E0BQ@1,33SG4@2,47TMP@768503,4P0E6@976 NA|NA|NA MAG.T22.3_01431 1239962.C943_01497 1.4e-86 325.5 Cytophagia nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02601,ko:K05785 ko00000,ko03000,ko03009,ko03021 Bacteria 47S81@768503,4NSVU@976,COG0250@1,COG0250@2 NA|NA|NA K Transcription termination factor nusG MAG.T22.3_01432 1239962.C943_01499 0.0 2006.1 Cytophagia acrD ko:K18989 M00720 ko00000,ko00002,ko02000 2.A.6.2.30 Bacteria 47ME1@768503,4NDZG@976,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T22.3_01433 1239962.C943_01500 7.9e-181 639.8 Cytophagia cusB ko:K13888,ko:K18990 M00709,M00720 ko00000,ko00002,ko02000 2.A.6.2.30,8.A.1 Bacteria 47MFI@768503,4NERP@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.3_01434 1239962.C943_01501 1.1e-232 812.4 Cytophagia Bacteria 47KE9@768503,4NF4X@976,COG1538@1,COG1538@2 NA|NA|NA MU PFAM Outer membrane efflux protein MAG.T22.3_01435 1239962.C943_01502 1.9e-112 411.8 Cytophagia ko:K09017 ko00000,ko03000 Bacteria 47QGN@768503,4NQ99@976,COG1309@1,COG1309@2 NA|NA|NA K PFAM Bacterial regulatory proteins, tetR family MAG.T22.3_01436 1239962.C943_01503 1.2e-146 525.8 Cytophagia Bacteria 47PDP@768503,4PM2G@976,COG0596@1,COG0596@2 NA|NA|NA S alpha/beta hydrolase fold MAG.T22.3_01437 1239962.C943_01504 5.4e-95 353.6 Cytophagia Bacteria 47QK7@768503,4NNBE@976,COG1670@1,COG1670@2 NA|NA|NA J Polyketide cyclase / dehydrase and lipid transport MAG.T22.3_01438 1123057.P872_15785 3.5e-159 568.2 Cytophagia ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 Bacteria 47P0C@768503,4NU3A@976,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein MAG.T22.3_01439 1189612.A33Q_1389 1e-106 392.9 Cytophagia Bacteria 47N33@768503,4NEC5@976,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter MAG.T22.3_01440 1239962.C943_02795 1.2e-106 392.5 Bacteria Bacteria COG3391@1,COG3391@2 NA|NA|NA CO amine dehydrogenase activity MAG.T22.3_01441 1239962.C943_02793 0.0 1703.3 Bacteroidetes 2.7.13.3 ko:K07778 ko02020,map02020 M00479 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 4NPAJ@976,COG3292@1,COG3292@2,COG4585@1,COG4585@2 NA|NA|NA T Two component regulator three Y MAG.T22.3_01442 1239962.C943_02792 1.2e-82 312.8 Cytophagia degU Bacteria 47PWE@768503,4NHTM@976,COG2197@1,COG2197@2 NA|NA|NA KT Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain MAG.T22.3_01443 1239962.C943_02790 0.0 1198.3 Cytophagia Bacteria 47TNE@768503,4NMRZ@976,COG4585@1,COG4585@2 NA|NA|NA T 7TM diverse intracellular signalling MAG.T22.3_01444 1239962.C943_02789 6.9e-113 413.3 Cytophagia Bacteria 47VIW@768503,4NSGV@976,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon MAG.T22.3_01448 1034807.FBFL15_1010 1.9e-136 492.3 Flavobacterium ko:K09144 ko00000 Bacteria 1HX70@117743,2NVQH@237,4NMIN@976,COG2253@1,COG2253@2 NA|NA|NA S Nucleotidyl transferase AbiEii toxin, Type IV TA system MAG.T22.3_01449 1492737.FEM08_20330 5.8e-77 293.9 Flavobacteriia ko:K06919 ko00000 Bacteria 1IIBC@117743,4NP4G@976,COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score MAG.T22.3_01450 362418.IW19_12680 3.1e-105 389.4 Flavobacterium Bacteria 1IN91@117743,2F5RZ@1,2NYJM@237,30QTF@2,4PD14@976 NA|NA|NA MAG.T22.3_01451 755732.Fluta_2961 6.1e-46 191.0 Flavobacteriia 3.1.3.16 ko:K01090,ko:K20074 ko00000,ko01000,ko01009 Bacteria 1I5Q2@117743,4NT7V@976,COG0631@1,COG0631@2 NA|NA|NA T Serine/threonine phosphatases, family 2C, catalytic domain MAG.T22.3_01452 755732.Fluta_2960 0.0 2352.4 Bacteroidetes Bacteria 4NJRE@976,COG0433@1,COG0433@2 NA|NA|NA S COG0433 Predicted ATPase MAG.T22.3_01453 755732.Fluta_2959 3.2e-228 797.7 Bacteroidetes Bacteria 2CBBK@1,2ZADC@2,4P1G5@976 NA|NA|NA MAG.T22.3_01454 755732.Fluta_2958 0.0 1995.3 Flavobacteriia Bacteria 1I5VW@117743,4NPN9@976,COG0515@1,COG0515@2 NA|NA|NA KLT PFAM Protein kinase domain MAG.T22.3_01455 314260.PB2503_05682 6.2e-62 246.1 Proteobacteria 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1R4D4@1224,COG3973@1,COG3973@2 NA|NA|NA L DNA helicase MAG.T22.3_01456 755732.Fluta_2957 3.4e-85 322.4 Flavobacteriia 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1IA3J@117743,4P3GB@976,COG0732@1,COG0732@2 NA|NA|NA L Type I restriction modification DNA specificity domain MAG.T22.3_01457 755732.Fluta_2956 1.2e-309 1068.5 Flavobacteriia 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1HZWJ@117743,4NJ3U@976,COG0286@1,COG0286@2 NA|NA|NA L N-6 DNA Methylase MAG.T22.3_01458 1267211.KI669560_gene497 2.8e-46 192.2 Bacteroidetes Bacteria 28KWY@1,2ZAD1@2,4NM1H@976 NA|NA|NA MAG.T22.3_01459 880070.Cycma_3330 4.4e-11 73.6 Cytophagia Bacteria 2ESY9@1,33KGI@2,47T07@768503,4NZFJ@976 NA|NA|NA MAG.T22.3_01460 616991.JPOO01000003_gene60 1.5e-43 182.6 Flavobacteriia Bacteria 1I3F3@117743,4NQNI@976,COG1846@1,COG1846@2 NA|NA|NA K MarR family MAG.T22.3_01461 1004149.AFOE01000007_gene1504 4.8e-19 100.1 Flavobacteriia Bacteria 1I43N@117743,2E2UJ@1,32XWK@2,4NTCK@976 NA|NA|NA MAG.T22.3_01462 1123276.KB893247_gene137 4.6e-103 380.9 Cytophagia 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 47Y5S@768503,4NMPE@976,COG1051@1,COG1051@2,COG4111@1,COG4111@2 NA|NA|NA F PFAM NUDIX hydrolase MAG.T22.3_01463 357808.RoseRS_2551 6e-67 261.5 Chloroflexia Bacteria 2F1NI@1,2GBPE@200795,33PWB@2,377XB@32061 NA|NA|NA MAG.T22.3_01464 926549.KI421517_gene2837 8.2e-133 479.9 Cytophagia 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 R01394 RC00511 ko00000,ko00001,ko01000 Bacteria 47M10@768503,4NG0V@976,COG3622@1,COG3622@2 NA|NA|NA G Belongs to the hyi family MAG.T22.3_01465 1123276.KB893247_gene136 0.0 1789.2 Cytophagia ko:K08738,ko:K09992 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 47MAT@768503,4NDVK@976,COG2133@1,COG2133@2,COG3291@1,COG3291@2,COG3828@1,COG3828@2,COG4654@1,COG4654@2 NA|NA|NA CG Cytochrome c, class I MAG.T22.3_01466 1123277.KB893197_gene6096 6.6e-23 113.6 Cytophagia Bacteria 47RCR@768503,4NSKI@976,COG4654@1,COG4654@2 NA|NA|NA C Cytochrome c, class I MAG.T22.3_01467 1121904.ARBP01000021_gene3593 4.1e-287 993.8 Cytophagia Bacteria 47MGM@768503,4NG61@976,COG3794@1,COG3794@2 NA|NA|NA C PFAM blue (type 1) copper domain protein MAG.T22.3_01468 326427.Cagg_3168 3.6e-79 301.6 Chloroflexia Bacteria 2G8EB@200795,377GA@32061,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T22.3_01470 1237149.C900_03881 8.3e-36 157.1 Bacteroidetes Bacteria 2DRAR@1,33AZK@2,4NYVX@976 NA|NA|NA S HNH nucleases MAG.T22.3_01471 1123057.P872_06050 2.1e-32 145.6 Cytophagia Bacteria 2F8F8@1,340TZ@2,47VGW@768503,4P45Y@976 NA|NA|NA MAG.T22.3_01472 1121898.Q766_02745 4.5e-31 141.7 Flavobacterium Bacteria 1I59G@117743,28J01@1,2NV42@237,2Z8XB@2,4NGTC@976 NA|NA|NA MAG.T22.3_01473 880070.Cycma_3285 1e-26 127.1 Cytophagia Bacteria 2EUIP@1,33N0Q@2,47V1P@768503,4NXZ8@976 NA|NA|NA MAG.T22.3_01474 1120968.AUBX01000017_gene2004 1.3e-133 482.6 Bacteroidetes Bacteria 2DM79@1,320XV@2,4NQEA@976 NA|NA|NA S Protein of unknown function (DUF4099) MAG.T22.3_01475 1120968.AUBX01000017_gene2003 1.7e-55 222.6 Cytophagia Bacteria 47VM0@768503,4PIE7@976,COG0739@1,COG0739@2 NA|NA|NA M Peptidase family M23 MAG.T22.3_01476 1120968.AUBX01000017_gene2002 0.0 1153.7 Cytophagia Bacteria 47KQZ@768503,4NFHI@976,COG3505@1,COG3505@2 NA|NA|NA U TraM recognition site of TraD and TraG MAG.T22.3_01477 1120968.AUBX01000017_gene2001 1.3e-127 462.6 Cytophagia comB2 ko:K03204,ko:K12049 ko03070,map03070 M00333 ko00000,ko00001,ko00002,ko02044 3.A.7,3.A.7.8.1 Bacteria 47R2S@768503,4NH1R@976,COG3504@1,COG3504@2 NA|NA|NA U Domain of unknown function (DUF4138) MAG.T22.3_01478 1120968.AUBX01000017_gene2000 2e-169 602.1 Bacteroidetes Bacteria 28HNW@1,2ZAEE@2,4NHT7@976 NA|NA|NA S Conjugative transposon TraM protein MAG.T22.3_01479 1123057.P872_06100 2.4e-13 82.0 Cytophagia Bacteria 2C57B@1,343WG@2,47W6K@768503,4P5BP@976 NA|NA|NA MAG.T22.3_01480 1120968.AUBX01000017_gene1998 1.3e-100 372.5 Cytophagia trbF ko:K03200,ko:K20531 ko02024,ko03070,map02024,map03070 M00333 ko00000,ko00001,ko00002,ko02044 3.A.7,3.A.7.4 Bacteria 47XVY@768503,4NHQ2@976,COG3701@1,COG3701@2 NA|NA|NA U Conjugative transposon TraK protein MAG.T22.3_01481 1120968.AUBX01000017_gene1997 2.6e-187 661.4 Bacteroidetes Bacteria 28IXG@1,2Z8VD@2,4NHTT@976 NA|NA|NA MAG.T22.3_01482 1120968.AUBX01000017_gene1996 8.9e-115 419.9 Bacteroidetes Bacteria 28JQT@1,2Z9GJ@2,4NJK9@976 NA|NA|NA MAG.T22.3_01483 1120968.AUBX01000017_gene1995 1.6e-88 332.4 Bacteroidetes Bacteria 2DNEP@1,32X4M@2,4NUAR@976 NA|NA|NA MAG.T22.3_01484 1120968.AUBX01000017_gene1994 2.5e-86 325.1 Bacteroidetes Bacteria 2C5H7@1,3359Z@2,4NWN2@976 NA|NA|NA MAG.T22.3_01485 1120968.AUBX01000017_gene1993 7.1e-97 360.1 Bacteroidetes Bacteria 2DBWC@1,2ZBG2@2,4NPZA@976 NA|NA|NA MAG.T22.3_01486 1120968.AUBX01000017_gene1992 0.0 1472.6 Cytophagia traC ko:K12063 ko00000,ko02044 3.A.7.11.1 Bacteria 47N1V@768503,4NER7@976,COG3451@1,COG3451@2 NA|NA|NA U TIGRFAM Bacteroides conjugation system ATPase, TraG family MAG.T22.3_01487 1120968.AUBX01000017_gene1991 2.1e-37 161.4 Cytophagia Bacteria 2ECMI@1,336JJ@2,47VF6@768503,4NX7D@976 NA|NA|NA MAG.T22.3_01488 1120968.AUBX01000017_gene1990 1e-36 159.1 Cytophagia Bacteria 2DMI6@1,32RQ4@2,47X6Q@768503,4NSKV@976 NA|NA|NA S Domain of unknown function (DUF4134) MAG.T22.3_01489 880070.Cycma_3268 7.8e-20 103.2 Cytophagia Bacteria 2AV4I@1,339PH@2,47VB5@768503,4NYPF@976 NA|NA|NA S Domain of unknown function (DUF4134) MAG.T22.3_01491 880070.Cycma_3266 4.3e-13 80.9 Cytophagia Bacteria 2FGWM@1,348RX@2,47VPM@768503,4P6J6@976 NA|NA|NA MAG.T22.3_01492 1120968.AUBX01000017_gene1986 2.1e-104 385.2 Bacteroidetes ko:K03496 ko00000,ko03036,ko04812 Bacteria 4NMTC@976,COG1192@1,COG1192@2 NA|NA|NA D AAA domain MAG.T22.3_01493 1120968.AUBX01000017_gene1985 2.9e-190 671.4 Bacteroidetes Bacteria 4NJVA@976,COG3843@1,COG3843@2 NA|NA|NA U Relaxase mobilization nuclease MAG.T22.3_01494 880070.Cycma_3263 1.8e-08 65.1 Cytophagia Bacteria 2E9XY@1,33GQZ@2,47VIE@768503,4NZBK@976 NA|NA|NA S Bacterial mobilisation protein (MobC) MAG.T22.3_01495 1120968.AUBX01000017_gene1983 4e-130 471.1 Bacteroidetes Bacteria 4NNE9@976,COG2197@1,COG2197@2 NA|NA|NA KT Pfam Bacterial regulatory proteins, luxR family MAG.T22.3_01496 1120968.AUBX01000017_gene1982 2.9e-83 314.7 Cytophagia Bacteria 47QU8@768503,4NQIV@976,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family MAG.T22.3_01497 1123057.P872_06195 7.6e-25 120.2 Cytophagia Bacteria 2DD83@1,2ZGZH@2,47X2J@768503,4P73E@976 NA|NA|NA MAG.T22.3_01498 1120968.AUBX01000017_gene1980 2.9e-115 421.4 Cytophagia ko:K03496 ko00000,ko03036,ko04812 Bacteria 47NCJ@768503,4NGFE@976,COG1192@1,COG1192@2 NA|NA|NA D Cellulose biosynthesis protein BcsQ MAG.T22.3_01500 1094466.KQS_01395 1.8e-77 295.8 Flavobacteriia Bacteria 1I3R7@117743,2BA14@1,323EW@2,4NRAX@976 NA|NA|NA MAG.T22.3_01501 1120966.AUBU01000005_gene3839 1.1e-56 226.1 Bacteroidetes radC ko:K03630 ko00000 Bacteria 4NRCM@976,COG2003@1,COG2003@2 NA|NA|NA L DNA repair protein MAG.T22.3_01502 1408813.AYMG01000013_gene1223 2.2e-46 193.0 Bacteroidetes Bacteria 2DRM2@1,33C8R@2,4P5P3@976 NA|NA|NA MAG.T22.3_01503 796620.VIBC2010_05149 2.4e-10 73.6 Vibrionales Bacteria 1N3D9@1224,1SAIK@1236,1XYM9@135623,28M8W@1,2ZAMX@2 NA|NA|NA S Domain of unknown function (DUF4062) MAG.T22.3_01504 1120968.AUBX01000017_gene2027 9.5e-117 426.8 Cytophagia Bacteria 47SS4@768503,4NH5X@976,COG0358@1,COG0358@2 NA|NA|NA L Toprim-like MAG.T22.3_01505 1120968.AUBX01000017_gene2028 3.4e-162 577.8 Cytophagia fimY ko:K08088 ko00000 Bacteria 47NH3@768503,4NES9@976,COG2197@1,COG2197@2 NA|NA|NA KT AAA domain MAG.T22.3_01507 880070.Cycma_4609 7.3e-27 126.3 Cytophagia Bacteria 2DWZ7@1,342MT@2,47VJD@768503,4P4WK@976 NA|NA|NA S Helix-turn-helix domain MAG.T22.3_01508 1123057.P872_09655 3.4e-35 155.6 Cytophagia Bacteria 2EDXV@1,337SR@2,47S2F@768503,4NVYC@976 NA|NA|NA MAG.T22.3_01509 1120968.AUBX01000017_gene2031 4e-176 624.4 Cytophagia Bacteria 47QUU@768503,4PKMN@976,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family MAG.T22.3_01510 1239962.C943_00116 5.6e-194 683.7 Cytophagia Bacteria 47KFM@768503,4NF61@976,COG2133@1,COG2133@2 NA|NA|NA G Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MAG.T22.3_01511 1239962.C943_00117 0.0 1843.2 Cytophagia Bacteria 47UCB@768503,4NPTY@976,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C Cytochrome c MAG.T22.3_01513 1239962.C943_00122 6.9e-181 639.8 Cytophagia Bacteria 47YQP@768503,4PNCU@976,COG1413@1,COG1413@2 NA|NA|NA C Domain of Unknown Function (DUF1080) MAG.T22.3_01514 1239962.C943_00123 7.2e-39 166.0 Cytophagia YPO1157 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 ko:K06867 ko00000 Bacteria 47RWW@768503,4NUS1@976,COG4628@1,COG4628@2 NA|NA|NA S conserved protein (DUF2132) MAG.T22.3_01515 1239962.C943_00124 0.0 1200.3 Bacteria dMI1 3.1.4.46 ko:K01126,ko:K10716 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 Bacteria COG1226@1,COG1226@2 NA|NA|NA P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) MAG.T22.3_01516 1239962.C943_00127 0.0 1297.3 Cytophagia feoB ko:K04759 ko00000,ko02000 9.A.8.1 Bacteria 47JEQ@768503,4NEII@976,COG0370@1,COG0370@2 NA|NA|NA P transporter of a GTP-driven Fe(2 ) uptake system MAG.T22.3_01517 1239962.C943_00131 4.1e-52 210.3 Cytophagia hrpX GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0030260,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0044403,GO:0044409,GO:0044419,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0060255,GO:0065007,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 Bacteria 47RUM@768503,4NVDF@976,COG2207@1,COG2207@2 NA|NA|NA K Transcriptional regulator MAG.T22.3_01518 1239962.C943_00132 2e-53 215.3 Cytophagia Bacteria 2BW9M@1,32RJH@2,47RBU@768503,4NTHJ@976 NA|NA|NA MAG.T22.3_01519 1239962.C943_00133 5.6e-68 263.8 Bacteria MA20_20735 Bacteria COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator MAG.T22.3_01520 1239962.C943_00134 4.3e-182 644.0 Bacteria Bacteria 28M5B@1,2ZAJ4@2 NA|NA|NA MAG.T22.3_01521 1239962.C943_00135 3.9e-129 467.6 Cytophagia cah 4.2.1.1 ko:K01674 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 Bacteria 47SK9@768503,4NK9J@976,COG3338@1,COG3338@2 NA|NA|NA P Eukaryotic-type carbonic anhydrase MAG.T22.3_01522 1239962.C943_00136 6.3e-210 736.5 Bacteroidetes opdC Bacteria 4PNED@976,COG3203@1,COG3203@2 NA|NA|NA M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane MAG.T22.3_01523 1239962.C943_00137 3.3e-80 304.3 Bacteroidetes Bacteria 2CWBN@1,32SZD@2,4NU6S@976 NA|NA|NA MAG.T22.3_01524 1239962.C943_00138 0.0 1460.3 Cytophagia ko:K07277 ko00000,ko02000,ko03029 1.B.33 Bacteria 47KRB@768503,4NE80@976,COG4775@1,COG4775@2 NA|NA|NA M Outer membrane protein protective antigen OMA87 MAG.T22.3_01525 1239962.C943_00139 0.0 3030.7 Cytophagia Bacteria 47JE0@768503,4NF7F@976,COG2911@1,COG2911@2 NA|NA|NA M PFAM Family of MAG.T22.3_01526 1239962.C943_00142 2.8e-81 307.8 Cytophagia MA20_02285 2.3.1.57 ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 M00135 R01154 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 47QJM@768503,4PP5U@976,COG0454@1,COG0454@2 NA|NA|NA K Acetyltransferase (GNAT) domain MAG.T22.3_01527 1239962.C943_00146 7.3e-116 423.3 Cytophagia Bacteria 47R4Q@768503,4NSYY@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.3_01528 1239962.C943_00147 3.3e-269 933.7 Cytophagia cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 47KFG@768503,4NF1S@976,COG0617@1,COG0617@2 NA|NA|NA J Poly A polymerase head domain MAG.T22.3_01529 1239962.C943_00148 2.5e-80 304.7 Cytophagia Bacteria 2F5JY@1,33Y55@2,47V38@768503,4P36U@976 NA|NA|NA MAG.T22.3_01530 269798.CHU_2401 3.3e-33 147.9 Cytophagia Bacteria 2DF5F@1,32U4P@2,47SJG@768503,4NTSC@976 NA|NA|NA MAG.T22.3_01531 1239962.C943_00152 2.5e-88 331.6 Cytophagia Bacteria 47V9A@768503,4NNMA@976,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase MAG.T22.3_01532 1239962.C943_00154 6.3e-72 276.6 Cytophagia Bacteria 2AKGE@1,31B89@2,47UY0@768503,4NQ22@976 NA|NA|NA MAG.T22.3_01533 1239962.C943_00157 1.7e-309 1067.8 Cytophagia pyrG GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iNJ661.Rv1699,iPC815.YPO3377 Bacteria 47KXM@768503,4NEWT@976,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates MAG.T22.3_01534 1239962.C943_00158 0.0 1099.0 Cytophagia yidC GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 47KF7@768503,4NESJ@976,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins MAG.T22.3_01535 1239962.C943_00159 4.6e-123 447.2 Cytophagia ytkL Bacteria 47KU7@768503,4NGD5@976,COG2220@1,COG2220@2 NA|NA|NA S Belongs to the UPF0173 family MAG.T22.3_01536 1239962.C943_00160 2e-138 498.4 Cytophagia soj ko:K03496 ko00000,ko03036,ko04812 Bacteria 47JM3@768503,4NFEX@976,COG1192@1,COG1192@2 NA|NA|NA D PFAM CobQ CobB MinD ParA nucleotide binding domain MAG.T22.3_01537 1239962.C943_00161 5.6e-164 583.6 Cytophagia noc ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 47K9I@768503,4NFZ9@976,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family MAG.T22.3_01538 1239962.C943_00162 1.3e-96 359.0 Cytophagia Bacteria 28PR3@1,2ZCD0@2,47RVI@768503,4NMAF@976 NA|NA|NA MAG.T22.3_01539 1239962.C943_00163 3.7e-123 447.6 Cytophagia dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1520 Bacteria 47KG4@768503,4NDX2@976,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate MAG.T22.3_01540 1239962.C943_00165 5.9e-210 736.5 Cytophagia lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 47JH7@768503,4NFTP@976,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family MAG.T22.3_01542 1239962.C943_00168 7.7e-217 759.6 Cytophagia Bacteria 47JWT@768503,4NE2H@976,COG5505@1,COG5505@2 NA|NA|NA S integral membrane protein MAG.T22.3_01543 1239962.C943_00169 6.8e-105 386.7 Cytophagia nudL GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 Bacteria 47MQZ@768503,4NM6C@976,COG0494@1,COG0494@2 NA|NA|NA L pfam nudix MAG.T22.3_01544 1239962.C943_00170 5.7e-113 413.7 Cytophagia Bacteria 2DV2Z@1,33TTB@2,47UTP@768503,4P2RT@976 NA|NA|NA MAG.T22.3_01545 1239962.C943_00171 0.0 1134.4 Cytophagia aceK GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 ko:K00906 ko00000,ko01000 Bacteria 47PA7@768503,4NIUY@976,COG4579@1,COG4579@2 NA|NA|NA T Isocitrate dehydrogenase MAG.T22.3_01546 1239962.C943_00172 1.3e-235 822.0 Bacteroidetes Bacteria 4NNE3@976,COG2885@1,COG2885@2 NA|NA|NA M chlorophyll binding MAG.T22.3_01547 1239962.C943_00173 0.0 1283.9 Cytophagia 3.1.1.53 ko:K05970 ko00000,ko01000 Bacteria 47JV2@768503,4NEDP@976,COG3250@1,COG3250@2 NA|NA|NA G Belongs to the glycosyl hydrolase 2 family MAG.T22.3_01548 1239962.C943_00174 5.6e-197 693.7 Cytophagia mgtE ko:K06213 ko00000,ko02000 1.A.26.1 Bacteria 47JTX@768503,4NGGN@976,COG2239@1,COG2239@2 NA|NA|NA P Acts as a magnesium transporter MAG.T22.3_01549 1239962.C943_00175 4.4e-146 523.9 Cytophagia ksgA GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 ko:K02528 R10716 RC00003,RC03257 ko00000,ko01000,ko03009 Bacteria 47KWT@768503,4NERB@976,COG0030@1,COG0030@2 NA|NA|NA J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits MAG.T22.3_01550 1239962.C943_00176 2.2e-190 671.4 Cytophagia pdxA 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 Bacteria 47MC9@768503,4NEUR@976,COG1995@1,COG1995@2 NA|NA|NA H Belongs to the PdxA family MAG.T22.3_01551 1239962.C943_00177 5.8e-79 300.4 Cytophagia yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 47QNM@768503,4NMQT@976,COG1399@1,COG1399@2 NA|NA|NA S Uncharacterized ACR, COG1399 MAG.T22.3_01552 1123057.P872_24490 1.6e-25 121.3 Cytophagia rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 47S89@768503,4NUXU@976,COG0333@1,COG0333@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL32 family MAG.T22.3_01554 1239962.C943_00180 2.2e-190 671.4 Cytophagia fabH 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 47KV4@768503,4NEYH@976,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids MAG.T22.3_01555 1239962.C943_00181 5.7e-95 353.6 Cytophagia efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 47MZS@768503,4NDXA@976,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase MAG.T22.3_01556 1239962.C943_00182 1.2e-64 252.7 Cytophagia accB 2.3.1.12,4.1.1.3 ko:K00627,ko:K01571,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00217,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 Bacteria 47PSK@768503,4NM8U@976,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA MAG.T22.3_01557 1239962.C943_00183 2.5e-258 897.5 Cytophagia accC 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 47MHE@768503,4NFEQ@976,COG0439@1,COG0439@2 NA|NA|NA I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase MAG.T22.3_01558 1239962.C943_00184 0.0 1743.0 Cytophagia valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iLJ478.TM1817 Bacteria 47JHX@768503,4NETB@976,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner MAG.T22.3_01559 1239962.C943_00185 3.5e-178 630.9 Bacteroidetes Bacteria 2AB14@1,339IP@2,4NZD5@976 NA|NA|NA MAG.T22.3_01560 1239962.C943_00186 1.5e-104 385.6 Cytophagia Bacteria 2CM52@1,30K3G@2,47X2H@768503,4PB8T@976 NA|NA|NA MAG.T22.3_01561 388413.ALPR1_13030 2.5e-42 177.9 Cytophagia phnA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06193 ko01120,map01120 ko00000 Bacteria 47QCE@768503,4NEFZ@976,COG2824@1,COG2824@2 NA|NA|NA P TIGRFAM alkylphosphonate utilization operon protein PhnA MAG.T22.3_01563 1239962.C943_00187 2.7e-290 1003.8 Cytophagia Bacteria 47JNX@768503,4NEN5@976,COG0673@1,COG0673@2 NA|NA|NA S PFAM Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.3_01564 1239962.C943_00188 1.7e-171 608.6 Cytophagia hutG 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 Bacteria 47SGD@768503,4NEFA@976,COG0010@1,COG0010@2 NA|NA|NA E Belongs to the arginase family MAG.T22.3_01565 1239962.C943_00189 3.8e-70 270.8 Cytophagia ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 47R7Q@768503,4NQXY@976,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family MAG.T22.3_01566 1239962.C943_00191 3.6e-109 401.0 Cytophagia 3.2.1.52,3.5.1.28 ko:K01207,ko:K01447,ko:K11066 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R04112,R05963,R07809,R07810,R10831 RC00049,RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011 Bacteria 47PNG@768503,4NMIV@976,COG3023@1,COG3023@2 NA|NA|NA V N-acetylmuramoyl-L-alanine amidase MAG.T22.3_01567 1239962.C943_00192 0.0 1076.2 Cytophagia Bacteria 47KD5@768503,4NFKQ@976,COG1649@1,COG1649@2 NA|NA|NA M PFAM Uncharacterised BCR, COG1649 MAG.T22.3_01568 1239962.C943_00193 9.1e-86 322.8 Cytophagia Bacteria 47UKD@768503,4P2N9@976,COG3153@1,COG3153@2 NA|NA|NA S Acetyltransferase (GNAT) family MAG.T22.3_01569 1239962.C943_00194 1.5e-236 825.1 Cytophagia ampG ko:K08218 ko01501,map01501 M00628 ko00000,ko00001,ko00002,ko02000 2.A.1.25 Bacteria 47P1A@768503,4NG5F@976,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T22.3_01570 1239962.C943_00195 1.3e-115 422.5 Cytophagia ko:K09807 ko00000 Bacteria 47SXQ@768503,4NVGQ@976,COG2968@1,COG2968@2 NA|NA|NA S Protein of unknown function (DUF541) MAG.T22.3_01572 983548.Krodi_1635 3.6e-90 338.2 Flavobacteriia Bacteria 1I5S9@117743,4NRSC@976,COG3076@1,COG3076@2 NA|NA|NA S TIGR01619 family MAG.T22.3_01573 880070.Cycma_1563 1.3e-22 112.8 Bacteroidetes Bacteria 2FJZN@1,34BN0@2,4P64M@976 NA|NA|NA MAG.T22.3_01574 323850.Shew_2602 9.4e-09 66.2 Bacteria Bacteria 28XPY@1,2ZJKQ@2 NA|NA|NA MAG.T22.3_01576 1239962.C943_00197 1.6e-154 552.0 Cytophagia tyrA 1.3.1.12,1.3.1.43 ko:K00210,ko:K00220,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025,M00040 R00732,R01728 RC00125 ko00000,ko00001,ko00002,ko01000 Bacteria 47N0Z@768503,4NEKF@976,COG0287@1,COG0287@2 NA|NA|NA E Prephenate dehydrogenase MAG.T22.3_01577 1239962.C943_00198 3.5e-211 740.7 Cytophagia dapL 2.6.1.83 ko:K10206 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 M00527 R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 47KXG@768503,4NF2E@976,COG0436@1,COG0436@2 NA|NA|NA E PFAM Aminotransferase class I and II MAG.T22.3_01578 1239962.C943_00199 1.1e-155 555.8 Cytophagia pheA 4.2.1.51,5.4.99.5 ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria 47NM0@768503,4NEEK@976,COG0077@1,COG0077@2 NA|NA|NA E PFAM Prephenate dehydratase MAG.T22.3_01579 1089547.KB913013_gene387 1.8e-23 115.5 Cytophagia vapC1 Bacteria 47T60@768503,4NU3R@976,COG1487@1,COG1487@2 NA|NA|NA S PIN domain MAG.T22.3_01581 1239962.C943_00200 2.3e-60 238.0 Cytophagia ko:K09922 ko00000 Bacteria 47QJ9@768503,4NQH4@976,COG3169@1,COG3169@2 NA|NA|NA S Putative member of DMT superfamily (DUF486) MAG.T22.3_01582 203275.BFO_3176 4.6e-59 235.0 Porphyromonadaceae ko:K07497 ko00000 Bacteria 22YVN@171551,2FRAQ@200643,4NKGS@976,COG2801@1,COG2801@2 NA|NA|NA L PFAM Integrase core domain MAG.T22.3_01583 459349.CLOAM0144 3.1e-12 78.2 Bacteria ko:K07497 ko00000 Bacteria COG2963@1,COG2963@2 NA|NA|NA L transposase activity MAG.T22.3_01584 1239962.C943_01096 0.0 1385.2 Cytophagia ppk GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 iJN746.PP_5217 Bacteria 47KMU@768503,4NE3P@976,COG0855@1,COG0855@2 NA|NA|NA P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) MAG.T22.3_01585 1239962.C943_01095 0.0 1223.4 Cytophagia gyrB GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 47K1X@768503,4NE0P@976,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner MAG.T22.3_01586 1239962.C943_01094 6.3e-55 219.9 Cytophagia ko:K06929 ko00000 Bacteria 47RGM@768503,4NSE8@976,COG1832@1,COG1832@2 NA|NA|NA S CoA binding domain MAG.T22.3_01587 1239962.C943_01093 4.5e-185 653.7 Cytophagia Bacteria 47M81@768503,4PKEK@976,COG3176@1,COG3176@2 NA|NA|NA S Acetyltransferase (GNAT) domain MAG.T22.3_01588 1239962.C943_01092 3.7e-125 454.1 Cytophagia Bacteria 47NUX@768503,4NF25@976,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases MAG.T22.3_01589 1239962.C943_01091 1.3e-140 505.8 Cytophagia Bacteria 47MTY@768503,4NKUV@976,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase MAG.T22.3_01590 1239962.C943_01090 1.6e-148 531.9 Cytophagia surE 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 47JN8@768503,4NEJ5@976,COG0496@1,COG0496@2 NA|NA|NA S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates MAG.T22.3_01591 1123057.P872_24650 2.9e-80 305.1 Cytophagia Bacteria 2CYF8@1,32T43@2,47RBY@768503,4NUAU@976 NA|NA|NA MAG.T22.3_01592 1239962.C943_01088 4.1e-231 807.0 Cytophagia ribBA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS10830,iSB619.SA_RS08945 Bacteria 47KP9@768503,4NF6I@976,COG0108@1,COG0108@2,COG0807@1,COG0807@2 NA|NA|NA H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate MAG.T22.3_01593 1239962.C943_01087 0.0 1217.6 Cytophagia dnaG GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 47K9B@768503,4NENT@976,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication MAG.T22.3_01594 1239962.C943_01086 5.3e-198 696.8 Cytophagia mrp ko:K03593 ko00000,ko03029,ko03036 Bacteria 47JZ3@768503,4NF5I@976,COG0489@1,COG0489@2 NA|NA|NA D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP MAG.T22.3_01595 1239962.C943_01085 6.9e-37 159.5 Cytophagia nifU Bacteria 47RA0@768503,4NSHJ@976,COG0694@1,COG0694@2 NA|NA|NA O NifU domain protein MAG.T22.3_01596 1239962.C943_01084 0.0 1967.2 Cytophagia Bacteria 47JD6@768503,4NGRJ@976,COG1404@1,COG1404@2,COG3291@1,COG3291@2 NA|NA|NA O PFAM Pregnancy-associated plasma protein-A MAG.T22.3_01597 1239962.C943_01083 1.7e-165 588.6 Cytophagia 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 47KEI@768503,4NGB3@976,COG0462@1,COG0462@2 NA|NA|NA EF Ribose-phosphate pyrophosphokinase MAG.T22.3_01598 1239962.C943_01082 2.8e-274 950.7 Cytophagia pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 iYO844.BSU31750 Bacteria 47MZ6@768503,4NFQK@976,COG1488@1,COG1488@2 NA|NA|NA H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP MAG.T22.3_01599 1239962.C943_01081 2e-101 375.2 Cytophagia ko:K03088,ko:K03091 ko00000,ko03021 Bacteria 47PTU@768503,4NM40@976,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family MAG.T22.3_01600 1120966.AUBU01000010_gene2928 3.7e-17 95.5 Cytophagia Bacteria 2FBI1@1,343PB@2,47UXK@768503,4NVZ6@976 NA|NA|NA MAG.T22.3_01601 1239962.C943_01079 8.4e-107 393.3 Cytophagia Bacteria 2EBB5@1,335BV@2,47WJ2@768503,4NUQ0@976 NA|NA|NA MAG.T22.3_01602 1239962.C943_01078 1.2e-207 729.2 Cytophagia Bacteria 47JQ1@768503,4NHCZ@976,COG0457@1,COG0457@2,COG4995@1,COG4995@2 NA|NA|NA S CHAT domain MAG.T22.3_01603 1239962.C943_03941 8.3e-118 429.9 Cytophagia yaaA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 ko:K09861 ko00000 Bacteria 47Q7T@768503,4NFP2@976,COG3022@1,COG3022@2 NA|NA|NA S Belongs to the UPF0246 family MAG.T22.3_01605 1239962.C943_03939 0.0 2097.4 Cytophagia Bacteria 47TPS@768503,4P20P@976,COG3291@1,COG3291@2 NA|NA|NA S Pkd domain containing protein MAG.T22.3_01606 1239962.C943_03937 0.0 1684.1 Cytophagia Bacteria 47UH9@768503,4P1H8@976,COG3291@1,COG3291@2 NA|NA|NA S Pkd domain containing protein MAG.T22.3_01607 1239962.C943_03936 1.7e-224 785.0 Cytophagia Bacteria 47YCD@768503,4PNC2@976,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T22.3_01608 1239962.C943_03935 5e-262 909.8 Cytophagia Bacteria 47M4E@768503,4NF3J@976,COG2730@1,COG2730@2 NA|NA|NA G Putative collagen-binding domain of a collagenase MAG.T22.3_01610 1239962.C943_03933 3.9e-66 257.3 Cytophagia Bacteria 47QR5@768503,4NQCJ@976,COG0346@1,COG0346@2 NA|NA|NA E PFAM Glyoxalase bleomycin resistance protein dioxygenase MAG.T22.3_01611 1239962.C943_03932 3.1e-122 444.5 Cytophagia Bacteria 47RZX@768503,4NF7G@976,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase MAG.T22.3_01612 1239962.C943_03931 9.5e-56 222.6 Cytophagia yciH GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K03113 ko03013,map03013 ko00000,ko00001,ko03012 Bacteria 47R38@768503,4NS6M@976,COG0023@1,COG0023@2 NA|NA|NA J PFAM translation initiation factor SUI1 MAG.T22.3_01613 1239962.C943_03930 2.7e-149 534.6 Cytophagia Bacteria 47PIA@768503,4NFZ5@976,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein MAG.T22.3_01614 1239962.C943_03928 4.5e-134 484.2 Cytophagia menA GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 iECH74115_1262.ECH74115_5387,iG2583_1286.G2583_4737 Bacteria 47JDA@768503,4NGCJ@976,COG1575@1,COG1575@2 NA|NA|NA H Belongs to the MenA family. Type 1 subfamily MAG.T22.3_01615 1239962.C943_03926 6.8e-104 383.3 Cytophagia btuE 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 Bacteria 47P7U@768503,4NM6G@976,COG0386@1,COG0386@2 NA|NA|NA O Belongs to the glutathione peroxidase family MAG.T22.3_01616 1239962.C943_03925 0.0 1181.8 Cytophagia argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 47K91@768503,4NE7Q@976,COG0018@1,COG0018@2 NA|NA|NA J Arginyl-tRNA synthetase MAG.T22.3_01617 1239962.C943_03924 3.1e-178 630.9 Cytophagia rocF 3.5.3.1,3.5.3.11,4.1.1.19 ko:K01476,ko:K01480,ko:K01585 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00133,M00134 R00551,R00566,R01157 RC00024,RC00299,RC00329 ko00000,ko00001,ko00002,ko01000 Bacteria 47N30@768503,4NE26@976,COG0010@1,COG0010@2 NA|NA|NA E Belongs to the arginase family MAG.T22.3_01618 1239962.C943_03922 2.6e-228 797.7 Cytophagia ykbA ko:K03294 ko00000 2.A.3.2 Bacteria 47NNC@768503,4NH7J@976,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease MAG.T22.3_01619 1239962.C943_03920 2.9e-218 764.2 Cytophagia ybdL GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008483,GO:0010326,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.6.1.17,2.6.1.88 ko:K14267,ko:K14287 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475,R08618 RC00006,RC00025 ko00000,ko00001,ko00002,ko01000,ko01007 iNJ661.Rv0858c Bacteria 47MBR@768503,4NES3@976,COG0436@1,COG0436@2 NA|NA|NA E PFAM Aminotransferase class I and II MAG.T22.3_01620 1239962.C943_03919 7e-145 520.0 Cytophagia Bacteria 47P2V@768503,4NMKR@976,COG3000@1,COG3000@2 NA|NA|NA I Fatty acid hydroxylase superfamily MAG.T22.3_01621 1239962.C943_03918 0.0 4518.8 Cytophagia 3.4.21.66 ko:K08651 ko00000,ko01000,ko01002,ko03110 Bacteria 47NC9@768503,4NF1M@976,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family MAG.T22.3_01622 1239962.C943_03916 7.2e-284 982.6 Bacteroidetes Bacteria 4NGS0@976,COG0457@1,COG0457@2 NA|NA|NA K tetratricopeptide repeat MAG.T22.3_01623 1239962.C943_03915 5.3e-123 447.2 Cytophagia pcm 2.1.1.77 ko:K00573 ko00000,ko01000 Bacteria 47MH9@768503,4NMTP@976,COG2518@1,COG2518@2 NA|NA|NA J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins MAG.T22.3_01624 1239962.C943_03913 5.9e-127 460.3 Cytophagia nosY ko:K01992,ko:K19341 ko02010,map02010 M00254,M00762 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.132.2 Bacteria 47KSX@768503,4NGGR@976,COG1277@1,COG1277@2 NA|NA|NA S ABC-2 family transporter protein MAG.T22.3_01625 1239962.C943_03912 1.4e-133 482.3 Cytophagia nosF ko:K01990,ko:K19340 ko02010,map02010 M00254,M00762 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.132.2 Bacteria 47PAA@768503,4NG9T@976,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter MAG.T22.3_01626 1239962.C943_03911 7.6e-209 733.0 Cytophagia nosD ko:K07218 ko00000 Bacteria 47KEF@768503,4NEGT@976,COG3420@1,COG3420@2 NA|NA|NA P Periplasmic copper-binding protein (NosD) MAG.T22.3_01627 866536.Belba_1977 1.4e-53 215.7 Cytophagia nosL ko:K19342 ko00000 Bacteria 47S32@768503,4NVVP@976,COG4314@1,COG4314@2 NA|NA|NA C NosL MAG.T22.3_01628 1123057.P872_04335 2.2e-78 298.5 Cytophagia nosL ko:K19342 ko00000 Bacteria 47NSZ@768503,4NIPU@976,COG4314@1,COG4314@2 NA|NA|NA C lipoprotein involved in nitrous oxide reduction MAG.T22.3_01629 1239962.C943_03909 0.0 1355.1 Cytophagia nosZ GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234 1.7.2.4,1.9.3.1 ko:K00376,ko:K02275 ko00190,ko00910,ko01100,ko01120,map00190,map00910,map01100,map01120 M00155,M00529 R00081,R02804 RC00016,RC02861 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 47KTB@768503,4NFNE@976,COG4263@1,COG4263@2 NA|NA|NA C Nitrous oxide reductase MAG.T22.3_01630 1239962.C943_03908 0.0 1152.5 Cytophagia Bacteria 47R42@768503,4NMD5@976,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T22.3_01631 1239962.C943_03907 1.3e-136 492.3 Cytophagia ko:K07322 ko00000 Bacteria 47P55@768503,4NE9M@976,COG2846@1,COG2846@2 NA|NA|NA D Di-iron-containing protein involved in the repair of iron-sulfur clusters MAG.T22.3_01632 1239962.C943_03906 3.2e-74 284.3 Cytophagia Bacteria 47V59@768503,4P34I@976,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator MAG.T22.3_01633 1239962.C943_03905 7.7e-100 369.8 Cytophagia Bacteria 47RIQ@768503,4NK2U@976,COG0664@1,COG0664@2 NA|NA|NA T Cyclic nucleotide-binding domain MAG.T22.3_01634 1239962.C943_03904 7.5e-126 456.4 Cytophagia Bacteria 2BVIX@1,32QWY@2,47T45@768503,4NRQE@976 NA|NA|NA MAG.T22.3_01635 1239962.C943_03903 7.9e-271 939.1 Cytophagia baeB 3.1.2.6,3.4.21.102 ko:K01069,ko:K03797 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000,ko01002 Bacteria 47MX5@768503,4NE2Y@976,COG0491@1,COG0491@2,COG0607@1,COG0607@2 NA|NA|NA P Zn-dependent hydrolase MAG.T22.3_01636 1239962.C943_03902 5.7e-115 420.2 Cytophagia Bacteria 47TCX@768503,4NPX1@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.3_01637 1239962.C943_03901 3.6e-249 867.1 Cytophagia Bacteria 2DBUI@1,32TY4@2,47TGU@768503,4NU5S@976 NA|NA|NA MAG.T22.3_01638 1239962.C943_03900 0.0 1439.9 Cytophagia yut GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009987,GO:0015204,GO:0015265,GO:0015267,GO:0015840,GO:0016020,GO:0016043,GO:0019755,GO:0022607,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0031226,GO:0033218,GO:0033219,GO:0036094,GO:0042802,GO:0042886,GO:0042887,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070206,GO:0070207,GO:0071702,GO:0071705,GO:0071840,GO:0071918,GO:0071944 ko:K08717 ko00000,ko02000 1.A.28.2 Bacteria 47SZN@768503,4NJUQ@976,COG0739@1,COG0739@2,COG4413@1,COG4413@2 NA|NA|NA EM Peptidase family M23 MAG.T22.3_01639 1239962.C943_03899 6.5e-262 909.4 Cytophagia lysA 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 47U1Q@768503,4NGRF@976,COG0019@1,COG0019@2 NA|NA|NA E Pyridoxal-dependent decarboxylase, pyridoxal binding domain MAG.T22.3_01640 1239962.C943_03898 5.8e-202 709.9 Cytophagia purD 6.3.4.13,6.3.5.5 ko:K01945,ko:K01955 ko00230,ko00240,ko00250,ko01100,ko01110,ko01130,map00230,map00240,map00250,map01100,map01110,map01130 M00048,M00051 R00256,R00575,R01395,R04144,R10948,R10949 RC00002,RC00010,RC00043,RC00090,RC00166,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 47TMM@768503,4NK50@976,COG0151@1,COG0151@2 NA|NA|NA F ATP-grasp domain MAG.T22.3_01641 1239962.C943_03897 6.9e-40 169.5 Cytophagia Bacteria 2EBCA@1,335D0@2,47VEH@768503,4NUYY@976 NA|NA|NA S Coenzyme PQQ synthesis protein D (PqqD) MAG.T22.3_01642 1239962.C943_03896 0.0 1904.8 Cytophagia ko:K03296 ko00000 2.A.6.2 Bacteria 47K19@768503,4NDZG@976,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T22.3_01643 1239962.C943_03895 6.2e-188 663.3 Cytophagia Bacteria 47NYC@768503,4NF23@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.3_01644 1239962.C943_03894 1.5e-215 755.4 Cytophagia ko:K03287 ko00000 1.B.17 Bacteria 47NMQ@768503,4NJFM@976,COG1538@1,COG1538@2 NA|NA|NA MU PFAM Outer membrane efflux protein MAG.T22.3_01645 1239962.C943_03893 1.3e-99 369.0 Cytophagia Bacteria 47PCH@768503,4NJJM@976,COG1309@1,COG1309@2 NA|NA|NA K YsiA-like protein, C-terminal region MAG.T22.3_01646 1189612.A33Q_2134 1.6e-49 202.2 Bacteroidetes Bacteria 4NURI@976,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator MAG.T22.3_01647 1239962.C943_03890 0.0 1567.0 Cytophagia norB 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 Bacteria 47K63@768503,4NG9H@976,COG3256@1,COG3256@2 NA|NA|NA P Cytochrome C and Quinol oxidase polypeptide I MAG.T22.3_01648 1239962.C943_03889 4.4e-74 283.9 Cytophagia ymaD Bacteria 47S0N@768503,4P9T2@976,COG1764@1,COG1764@2 NA|NA|NA O OsmC-like protein MAG.T22.3_01649 1239962.C943_03888 1.3e-105 389.0 Cytophagia nrdG 1.97.1.4,4.3.99.3 ko:K04069,ko:K10026 ko00790,ko01100,map00790,map01100 R04710,R10002 RC02989 ko00000,ko00001,ko01000,ko03016 Bacteria 47T80@768503,4NM78@976,COG1180@1,COG1180@2 NA|NA|NA O 4Fe-4S single cluster domain MAG.T22.3_01651 1239962.C943_03886 0.0 1420.2 Cytophagia nrdD 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 Bacteria 47NNY@768503,4NGPS@976,COG1328@1,COG1328@2 NA|NA|NA F Anaerobic ribonucleoside-triphosphate reductase MAG.T22.3_01652 1239962.C943_03884 0.0 1163.3 Cytophagia 1.13.12.16 ko:K00459 ko00910,map00910 R00025 RC02541,RC02759 ko00000,ko00001,ko01000 Bacteria 47JXU@768503,4NEGW@976,COG2070@1,COG2070@2 NA|NA|NA S 2-Nitropropane dioxygenase MAG.T22.3_01653 1239962.C943_03883 3.6e-211 740.7 Cytophagia 1.7.2.1 ko:K00368 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 Bacteria 47NIP@768503,4NJIE@976,COG4243@1,COG4243@2 NA|NA|NA S Vitamin k epoxide reductase MAG.T22.3_01654 926556.Echvi_4020 1.3e-10 72.8 Cytophagia Bacteria 2EGFG@1,33A7G@2,47SWI@768503,4P9MB@976 NA|NA|NA MAG.T22.3_01655 1239962.C943_03881 0.0 1471.8 Cytophagia oprC ko:K02014 ko00000,ko02000 1.B.14 Bacteria 47NS4@768503,4NFKZ@976,COG1629@1,COG4771@2 NA|NA|NA P TonB dependent receptor MAG.T22.3_01656 1239962.C943_03880 5e-124 450.7 Cytophagia zupT ko:K07238 ko00000,ko02000 2.A.5.5 Bacteria 47NUB@768503,4NGQ8@976,COG0428@1,COG0428@2 NA|NA|NA P PFAM ZIP Zinc transporter MAG.T22.3_01657 1239962.C943_03878 4.8e-67 260.4 Cytophagia ko:K09004 ko00000 Bacteria 47RWR@768503,4NUNC@976,COG1416@1,COG1416@2 NA|NA|NA S DsrE/DsrF-like family MAG.T22.3_01659 1239962.C943_03840 2.4e-187 661.4 Cytophagia glsA GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 Bacteria 47JMD@768503,4NERJ@976,COG2066@1,COG2066@2 NA|NA|NA E Belongs to the glutaminase family MAG.T22.3_01662 686578.AFFX01000002_gene649 8.4e-09 67.4 Bacteria Bacteria COG2928@1,COG2928@2 NA|NA|NA S Conserved Protein MAG.T22.3_01663 1239962.C943_03833 1.6e-191 675.2 Bacteroidetes Bacteria 4NPS9@976,COG5492@1,COG5492@2 NA|NA|NA N Putative carbohydrate metabolism domain MAG.T22.3_01664 1239962.C943_03832 1.2e-123 449.1 Bacteroidetes Bacteria 2DNY3@1,32ZR7@2,4NWGU@976 NA|NA|NA MAG.T22.3_01665 1239962.C943_03831 5.2e-59 233.8 Bacteroidetes Bacteria 2C0UK@1,32ZTA@2,4NUQ2@976 NA|NA|NA MAG.T22.3_01666 1239962.C943_03830 2.2e-156 558.1 Bacteroidetes Bacteria 4NPX9@976,COG3203@1,COG3203@2 NA|NA|NA M Alginate export MAG.T22.3_01667 1239962.C943_03830 4.5e-109 401.0 Bacteroidetes Bacteria 4NPX9@976,COG3203@1,COG3203@2 NA|NA|NA M Alginate export MAG.T22.3_01668 1433126.BN938_2809 7.2e-104 383.6 Rikenellaceae Bacteria 22U0F@171550,2FX2S@200643,4NEUB@976,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T22.3_01669 1239962.C943_03828 1.5e-46 191.8 Cytophagia Bacteria 47MT3@768503,4NEUB@976,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T22.3_01670 1121012.AUKX01000070_gene1860 1.4e-137 496.1 Flavobacteriia Bacteria 1HYYV@117743,2CB8G@1,2Z88H@2,4NF68@976 NA|NA|NA S Putative beta-barrel porin-2, OmpL-like. bbp2 MAG.T22.3_01671 1185876.BN8_02145 2.1e-54 218.4 Cytophagia Bacteria 293BF@1,2ZQU3@2,47Q3I@768503,4NNXE@976 NA|NA|NA MAG.T22.3_01672 760192.Halhy_6841 4.8e-43 181.0 Bacteroidetes MA20_20735 Bacteria 4NRRG@976,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family MAG.T22.3_01673 1239962.C943_03822 0.0 1508.0 Cytophagia ko:K02014,ko:K16087 ko00000,ko02000 1.B.14,1.B.14.2 Bacteria 47M16@768503,4NFZY@976,COG1629@1,COG4771@2 NA|NA|NA P TonB dependent receptor MAG.T22.3_01674 1239962.C943_03820 2.5e-84 318.2 Cytophagia Bacteria 2CJSY@1,32W7Z@2,47R1N@768503,4NUK7@976 NA|NA|NA MAG.T22.3_01675 1239962.C943_03819 3.6e-74 284.3 Cytophagia guaD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.12,3.5.4.3,3.5.4.33 ko:K01487,ko:K01493,ko:K11991 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00429 R01663,R01676,R10223 RC00074,RC00204,RC00477 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 Bacteria 47PPK@768503,4NNMU@976,COG0590@1,COG0590@2 NA|NA|NA FJ MafB19-like deaminase MAG.T22.3_01676 1239962.C943_03818 3.3e-127 461.1 Cytophagia Bacteria 47N0G@768503,4NI3K@976,COG3279@1,COG3279@2 NA|NA|NA T Two component transcriptional regulator, LytTR family MAG.T22.3_01677 1239962.C943_03817 2.8e-199 701.0 Cytophagia Bacteria 47ME5@768503,4NH1Q@976,COG2972@1,COG2972@2 NA|NA|NA T Histidine kinase MAG.T22.3_01678 1239962.C943_03815 0.0 1628.6 Cytophagia Bacteria 47JGS@768503,4NEIG@976,COG1629@1,COG4771@2 NA|NA|NA P TonB-dependent Receptor Plug MAG.T22.3_01679 1239962.C943_03814 1.7e-179 635.2 Cytophagia pdhB 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2753 Bacteria 47J9X@768503,4NE4N@976,COG0022@1,COG0022@2 NA|NA|NA C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase MAG.T22.3_01680 1239962.C943_03813 1.4e-66 258.8 Bacteria 2.7.7.80,2.8.1.11 ko:K21147 ko04122,map04122 R07459,R07461 RC00043 ko00000,ko00001,ko01000 Bacteria COG0607@1,COG0607@2 NA|NA|NA P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS MAG.T22.3_01681 1239962.C943_03812 1.1e-86 325.9 Cytophagia ko:K07095 ko00000 Bacteria 47QNZ@768503,4NM4G@976,COG0622@1,COG0622@2 NA|NA|NA S TIGRFAM phosphoesterase, MJ0936 family MAG.T22.3_01683 1239962.C943_03810 9.4e-253 879.0 Cytophagia hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 47KPD@768503,4NE8N@976,COG0124@1,COG0124@2 NA|NA|NA J tRNA synthetase class II core domain (G, H, P, S and T) MAG.T22.3_01684 1239962.C943_03809 1.4e-41 175.3 Cytophagia Bacteria 2E46C@1,33EHC@2,47T1K@768503,4NY42@976 NA|NA|NA MAG.T22.3_01685 1239962.C943_03808 3.4e-47 194.1 Cytophagia ybaB ko:K09747 ko00000 Bacteria 47R3V@768503,4NQ37@976,COG0718@1,COG0718@2 NA|NA|NA S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection MAG.T22.3_01686 1239962.C943_03807 6.2e-177 626.7 Cytophagia wbbL_2 ko:K07011 ko00000 Bacteria 47K2G@768503,4NFP0@976,COG1216@1,COG1216@2 NA|NA|NA S PFAM Glycosyl transferase family 2 MAG.T22.3_01687 1239962.C943_03805 0.0 1142.5 Cytophagia Bacteria 47KBE@768503,4NIJG@976,COG0457@1,COG0457@2 NA|NA|NA M Tetratricopeptide repeat protein MAG.T22.3_01689 1239962.C943_03804 0.0 2192.9 Cytophagia Bacteria 47KDP@768503,4NDXS@976,COG1629@1,COG1629@2 NA|NA|NA P TonB dependent receptor MAG.T22.3_01690 1239962.C943_03803 0.0 1171.4 Cytophagia ko:K21572 ko00000,ko02000 8.A.46.1,8.A.46.3 Bacteria 47Y41@768503,4NE3A@976,COG0446@1,COG0446@2 NA|NA|NA S SusD family MAG.T22.3_01691 1239962.C943_03802 0.0 2221.0 Cytophagia Bacteria 47JJ5@768503,4NEE8@976,COG4888@1,COG4888@2 NA|NA|NA S ASPIC and UnbV MAG.T22.3_01692 1239962.C943_03798 1.4e-37 161.8 Bacteria Bacteria 2EPV8@1,33HFQ@2 NA|NA|NA S Antitoxin Phd_YefM, type II toxin-antitoxin system MAG.T22.3_01693 1239962.C943_03797 1.3e-44 185.3 Bacteroidetes ko:K19158 ko00000,ko01000,ko02048 Bacteria 4NW06@976,COG4115@1,COG4115@2 NA|NA|NA S addiction module toxin, Txe YoeB family MAG.T22.3_01695 1233951.IO90_12840 7.8e-42 176.8 Bacteroidetes Bacteria 2E9KM@1,333TD@2,4P499@976 NA|NA|NA S Immunity protein 26 MAG.T22.3_01696 1239962.C943_01879 0.0 1157.5 Cytophagia Bacteria 47MK5@768503,4PMBP@976,COG0644@1,COG0644@2 NA|NA|NA C FAD dependent oxidoreductase MAG.T22.3_01697 1239962.C943_01880 8.8e-248 862.4 Cytophagia Bacteria 47JAV@768503,4NF9W@976,COG0671@1,COG0671@2 NA|NA|NA I PAP2 superfamily MAG.T22.3_01698 1239962.C943_01881 0.0 2191.4 Cytophagia Bacteria 47MQH@768503,4NEE8@976,COG4888@1,COG4888@2 NA|NA|NA S ASPIC UnbV domain protein MAG.T22.3_01699 1239962.C943_01882 5.2e-226 790.0 Cytophagia ko:K04096 ko00000 Bacteria 47K3B@768503,4NFZ1@976,COG0640@1,COG0640@2,COG1940@1,COG1940@2 NA|NA|NA GK Transcriptional regulator sugar kinase MAG.T22.3_01700 1239962.C943_01883 1.9e-97 361.7 Cytophagia manC 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 47Q0Y@768503,4NNWT@976,COG0662@1,COG0662@2 NA|NA|NA G PFAM Mannose-6-phosphate isomerase MAG.T22.3_01701 1239962.C943_01884 6.4e-182 643.7 Cytophagia ko:K20444 ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 47JYK@768503,4NI7Q@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.3_01702 1189612.A33Q_3127 2.8e-08 63.9 Cytophagia Bacteria 2CHG5@1,33BNC@2,47WK7@768503,4NXH2@976 NA|NA|NA MAG.T22.3_01703 1239962.C943_01888 6e-126 458.0 Cytophagia Bacteria 47PCS@768503,4NMDX@976,COG2849@1,COG2849@2 NA|NA|NA S MORN repeat variant MAG.T22.3_01704 926556.Echvi_3890 2.5e-26 125.6 Cytophagia Bacteria 2DWDY@1,33ZVH@2,47VB8@768503,4P45D@976 NA|NA|NA MAG.T22.3_01705 1239962.C943_01890 1.1e-186 659.1 Cytophagia fabH 2.3.1.180,2.3.1.262 ko:K00648,ko:K18003 ko00061,ko00405,ko01100,ko01130,ko01212,ko02024,ko02025,map00061,map00405,map01100,map01130,map01212,map02024,map02025 M00082,M00083 R10707,R11586,R11587,R11588 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 47JAR@768503,4NFIN@976,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids MAG.T22.3_01706 1239962.C943_01891 8.3e-173 612.8 Bacteroidetes fprA1 3.1.2.6 ko:K01069 ko00620,map00620 R01736 RC00004,RC00137 ko00000,ko00001,ko01000 Bacteria 4NHXR@976,COG0491@1,COG0491@2 NA|NA|NA S beta-lactamase domain protein MAG.T22.3_01707 1239962.C943_01892 2.9e-133 481.1 Cytophagia yoqW Bacteria 47XPZ@768503,4NI3T@976,COG2135@1,COG2135@2 NA|NA|NA S Belongs to the SOS response-associated peptidase family MAG.T22.3_01708 1239962.C943_01893 2.6e-185 654.4 Cytophagia ko:K07019 ko00000 Bacteria 47JJP@768503,4NFGZ@976,COG0429@1,COG0429@2 NA|NA|NA S Alpha beta hydrolase MAG.T22.3_01709 1239962.C943_01894 1.1e-292 1011.9 Cytophagia pdhC 1.2.4.1,2.3.1.12 ko:K00162,ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R02569,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02857,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 47KP4@768503,4NFB9@976,COG0508@1,COG0508@2 NA|NA|NA C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) MAG.T22.3_01710 1239962.C943_01895 9e-90 336.3 Cytophagia hslV GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 ko:K01419 ko00000,ko01000,ko01002 Bacteria 47MJS@768503,4NHZ8@976,COG5405@1,COG5405@2 NA|NA|NA O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery MAG.T22.3_01711 1120966.AUBU01000001_gene1170 6.4e-31 139.8 Bacteroidetes ko:K07461 ko00000 Bacteria 4NSI7@976,COG2827@1,COG2827@2 NA|NA|NA L endonuclease containing a URI domain MAG.T22.3_01712 1239962.C943_01897 2.5e-118 431.4 Cytophagia Bacteria 28HM7@1,2Z7VU@2,47PTW@768503,4NGV1@976 NA|NA|NA MAG.T22.3_01713 1239962.C943_01898 2.2e-251 874.4 Cytophagia Bacteria 47JE8@768503,4NDUP@976,COG0661@1,COG0661@2 NA|NA|NA S unusual protein kinase MAG.T22.3_01714 1239962.C943_01899 1.2e-150 539.3 Cytophagia Bacteria 47JT7@768503,4NG1K@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T22.3_01715 1239962.C943_01901 4.2e-222 776.9 Cytophagia Bacteria 47MXD@768503,4NDV1@976,COG2133@1,COG2133@2 NA|NA|NA G Glucose / Sorbosone dehydrogenase MAG.T22.3_01716 1122621.ATZA01000087_gene3351 1.8e-155 555.4 Sphingobacteriia Z012_07170 Bacteria 1IP18@117747,4NGY8@976,COG4804@1,COG4804@2 NA|NA|NA S Protein of unknown function (DUF1016) MAG.T22.3_01717 1239962.C943_01903 0.0 1217.6 Cytophagia yheS ko:K06158 ko00000,ko03012 Bacteria 47KHA@768503,4NG1W@976,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter MAG.T22.3_01718 1408473.JHXO01000005_gene1790 1.7e-148 532.3 Bacteroidia Bacteria 2FYGT@200643,4NIU8@976,COG0627@1,COG0627@2 NA|NA|NA S Putative esterase MAG.T22.3_01719 1239962.C943_01904 0.0 1212.2 Cytophagia Bacteria 47NUH@768503,4NIU8@976,COG0627@1,COG0627@2,COG4188@1,COG4188@2 NA|NA|NA E Putative esterase MAG.T22.3_01720 1239962.C943_01910 2.1e-241 841.3 Cytophagia 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 47Q56@768503,4NP9G@976,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family MAG.T22.3_01721 1239962.C943_01911 2e-149 535.0 Bacteroidetes Bacteria 4NIWM@976,COG1974@1,COG1974@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins MAG.T22.3_01722 1239962.C943_01912 1.1e-144 519.2 Cytophagia GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 ko:K14160 ko00000,ko03400 Bacteria 47UQP@768503,4NN6K@976,COG4544@1,COG4544@2 NA|NA|NA S Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division MAG.T22.3_01723 1239962.C943_01913 2.8e-242 844.3 Cytophagia imuB 2.7.7.7 ko:K02346,ko:K14161 ko00000,ko01000,ko03400 Bacteria 47TB1@768503,4NII1@976,COG0389@1,COG0389@2 NA|NA|NA L impB/mucB/samB family MAG.T22.3_01724 1239962.C943_01914 0.0 2113.2 Cytophagia dnaE2 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.6,2.7.7.7 ko:K00960,ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 47TPJ@768503,4NGTT@976,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase alpha chain like domain MAG.T22.3_01725 929556.Solca_1300 2.7e-17 94.7 Bacteroidetes Bacteria 2E4AT@1,32Z6G@2,4PQ0K@976 NA|NA|NA MAG.T22.3_01726 1239962.C943_01915 4.6e-76 290.4 Cytophagia gldH GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 Bacteria 2ADSH@1,313I2@2,47PP1@768503,4NQMU@976 NA|NA|NA S TIGRFAM Gliding motility-associated lipoprotein, GldH MAG.T22.3_01727 1239962.C943_01916 2.2e-204 718.4 Cytophagia yaaT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 Bacteria 47M8P@768503,4NENX@976,COG1774@1,COG1774@2 NA|NA|NA S PFAM PSP1 C-terminal conserved region MAG.T22.3_01728 1239962.C943_01918 1.1e-234 818.9 Cytophagia purD 6.3.4.13,6.3.5.3 ko:K01945,ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04463 RC00010,RC00090,RC00166,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 47JIA@768503,4NEUN@976,COG0151@1,COG0151@2 NA|NA|NA F Belongs to the GARS family MAG.T22.3_01729 1239962.C943_01919 0.0 1339.7 Cytophagia recQ 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 47JD8@768503,4NEB4@976,COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase RecQ MAG.T22.3_01730 1239962.C943_01920 5.2e-198 696.8 Cytophagia manC 2.7.7.13,5.3.1.8,5.4.2.8 ko:K00971,ko:K01840,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01818,R01819 RC00002,RC00376,RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 47KJZ@768503,4NE1Y@976,COG0836@1,COG0836@2 NA|NA|NA M TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase MAG.T22.3_01731 1239962.C943_01921 6.1e-97 360.1 Cytophagia Bacteria 2988D@1,2ZVE1@2,47SW6@768503,4NXMH@976 NA|NA|NA MAG.T22.3_01732 1239962.C943_01922 3.3e-192 677.6 Cytophagia romA Bacteria 47K8S@768503,4NI69@976,COG2220@1,COG2220@2 NA|NA|NA S Beta-lactamase superfamily domain MAG.T22.3_01733 1123057.P872_19570 9.4e-20 102.4 Cytophagia Bacteria 2DXG4@1,344VN@2,47VQN@768503,4P54V@976 NA|NA|NA MAG.T22.3_01734 1239962.C943_01924 0.0 1796.9 Cytophagia Bacteria 47MTC@768503,4NDZG@976,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T22.3_01735 1239962.C943_01925 8.8e-166 589.7 Cytophagia ko:K18302 M00642 ko00000,ko00002,ko01504,ko02000 2.A.6.2,8.A.1 Bacteria 47MIB@768503,4NF23@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.3_01736 1239962.C943_01926 4.2e-237 827.0 Cytophagia Bacteria 47KIE@768503,4NE4S@976,COG1538@1,COG1538@2 NA|NA|NA MU PFAM Outer membrane efflux protein MAG.T22.3_01737 1239962.C943_01927 6.2e-111 406.8 Cytophagia ttgR Bacteria 47PFA@768503,4NMR8@976,COG1309@1,COG1309@2 NA|NA|NA K WHG domain MAG.T22.3_01738 1239962.C943_01928 7.9e-233 812.8 Cytophagia fucP ko:K02429 ko00000,ko02000 2.A.1.7 Bacteria 47JBN@768503,4NEYR@976,COG0738@1,COG0738@2 NA|NA|NA G PFAM Major Facilitator Superfamily MAG.T22.3_01739 1239962.C943_01929 1.5e-133 482.3 Cytophagia Bacteria 47KYG@768503,4NH6R@976,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase MAG.T22.3_01740 1239962.C943_01930 6.5e-148 530.0 Cytophagia ko:K07046 ko00051,ko01120,map00051,map01120 R10689 RC00537 ko00000,ko00001,ko01000 Bacteria 47JKH@768503,4NFGB@976,COG3618@1,COG3618@2 NA|NA|NA S PFAM Amidohydrolase 2 MAG.T22.3_01741 1239962.C943_01931 7e-161 573.2 Cytophagia Bacteria 47N4F@768503,4NFMZ@976,COG0179@1,COG0179@2 NA|NA|NA Q PFAM fumarylacetoacetate (FAA) hydrolase MAG.T22.3_01742 1239962.C943_01932 3.7e-126 457.6 Cytophagia Bacteria 47JEU@768503,4NH6Y@976,COG1028@1,COG1028@2 NA|NA|NA IQ PFAM Short-chain dehydrogenase reductase SDR MAG.T22.3_01743 1239962.C943_01935 5.2e-123 447.2 Cytophagia Bacteria 28P7W@1,2ZC23@2,47TE7@768503,4NNAG@976 NA|NA|NA MAG.T22.3_01744 1239962.C943_01936 2.2e-179 634.8 Cytophagia Bacteria 47U31@768503,4P0UM@976,COG3064@1,COG3064@2 NA|NA|NA M Type IX secretion system membrane protein PorP/SprF MAG.T22.3_01745 1239962.C943_01937 3.7e-155 556.2 Bacteria ko:K15125 ko05133,map05133 ko00000,ko00001,ko00536 Bacteria COG2911@1,COG2911@2 NA|NA|NA S protein secretion MAG.T22.3_01747 641524.ADICYQ_4932 7.2e-116 423.7 Cytophagia ko:K07486 ko00000 Bacteria 47NU4@768503,4NKDC@976,COG3547@1,COG3547@2 NA|NA|NA L PFAM transposase IS116 IS110 IS902 family MAG.T22.3_01750 1239962.C943_02592 2.4e-169 601.3 Cytophagia yvrE GO:0003674,GO:0003824,GO:0004341,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016051,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0019852,GO:0019853,GO:0042364,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:1901576 ko:K14274 ko00040,map00040 R02427 RC00713 ko00000,ko00001,ko01000 Bacteria 47Q7V@768503,4NMJX@976,COG3386@1,COG3386@2 NA|NA|NA G SMP-30/Gluconolaconase/LRE-like region MAG.T22.3_01751 1239962.C943_02591 1.9e-166 591.7 Cytophagia Bacteria 47KBS@768503,4NK9X@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T22.3_01752 1239962.C943_02590 1.2e-146 525.8 Cytophagia Bacteria 47NEP@768503,4NK3I@976,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T22.3_01753 1239962.C943_02589 2.8e-201 707.6 Cytophagia gutB 1.1.1.1,1.1.1.14 ko:K00001,ko:K00008 ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 M00014 R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko00002,ko01000 Bacteria 47M9A@768503,4NJW8@976,COG1063@1,COG1063@2 NA|NA|NA E Alcohol dehydrogenase GroES-like domain MAG.T22.3_01754 1239962.C943_02588 2.4e-127 461.5 Bacteroidetes hxlA 4.1.2.43,5.3.1.27 ko:K08093,ko:K13831 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05338,R05339,R09780 RC00377,RC00421,RC00422 ko00000,ko00001,ko00002,ko01000 Bacteria 4NHBV@976,COG0269@1,COG0269@2 NA|NA|NA G Orotidine 5'-phosphate decarboxylase / HUMPS family MAG.T22.3_01755 1239962.C943_01484 8.4e-154 550.1 Bacteria 3.4.24.25,3.4.24.26 ko:K01399,ko:K08604,ko:K15125 ko01503,ko02024,ko05110,ko05111,ko05133,map01503,map02024,map05110,map05111,map05133 ko00000,ko00001,ko00536,ko01000,ko01002 Bacteria COG3266@1,COG3266@2,COG3291@1,COG3291@2 NA|NA|NA GM domain, Protein MAG.T22.3_01756 700598.Niako_6272 2.9e-80 305.8 Sphingobacteriia Bacteria 1IPSA@117747,4NH1Q@976,COG2972@1,COG2972@2 NA|NA|NA T regulator of cell autolysis MAG.T22.3_01757 700598.Niako_6273 3.2e-66 258.5 Sphingobacteriia Bacteria 1J04H@117747,4NI3K@976,COG3279@1,COG3279@2 NA|NA|NA K Response regulator of the LytR AlgR family MAG.T22.3_01758 1239962.C943_02582 8.5e-238 829.3 Cytophagia Bacteria 47JMS@768503,4NENF@976,COG2234@1,COG2234@2 NA|NA|NA S Peptidase, M28 MAG.T22.3_01759 1239962.C943_02581 2.2e-85 321.6 Cytophagia Bacteria 47PR7@768503,4NQBY@976,COG2318@1,COG2318@2 NA|NA|NA S DinB superfamily MAG.T22.3_01760 1239962.C943_02580 0.0 1102.4 Cytophagia Bacteria 47KHF@768503,4NEWA@976,COG0664@1,COG0664@2 NA|NA|NA T - Catabolite gene activator and regulatory subunit of cAMP-dependent protein MAG.T22.3_01761 1239962.C943_02579 1.4e-96 359.0 Cytophagia Bacteria 47PWB@768503,4NP3F@976,COG2353@1,COG2353@2 NA|NA|NA S YceI-like domain MAG.T22.3_01762 1239962.C943_02578 6.6e-248 862.8 Bacteroidetes Bacteria 2DBAQ@1,2Z848@2,4NFR9@976 NA|NA|NA MAG.T22.3_01763 1239962.C943_02577 1.2e-86 325.9 Cytophagia Bacteria 2DS7P@1,33EWE@2,47UYA@768503,4PPR3@976 NA|NA|NA MAG.T22.3_01764 1239962.C943_02576 3.8e-78 297.7 Bacteria Bacteria COG2353@1,COG2353@2 NA|NA|NA O YceI-like domain MAG.T22.3_01765 1239962.C943_02577 1.1e-42 179.9 Cytophagia Bacteria 2DS7P@1,33EWE@2,47UYA@768503,4PPR3@976 NA|NA|NA MAG.T22.3_01766 1239962.C943_02573 9.3e-245 852.4 Cytophagia argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47JA3@768503,4NFCY@976,COG0165@1,COG0165@2 NA|NA|NA E argininosuccinate lyase MAG.T22.3_01767 1239962.C943_02572 1.1e-187 662.5 Cytophagia argE 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 Bacteria 47KCS@768503,4NE2G@976,COG0624@1,COG0624@2 NA|NA|NA E PFAM Peptidase family M20 M25 M40 MAG.T22.3_01768 1239962.C943_02571 1.8e-142 511.9 Cytophagia argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0033554,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2508,iB21_1397.B21_03793,iEC55989_1330.EC55989_4441,iECB_1328.ECB_03844,iECDH10B_1368.ECDH10B_4147,iECDH1ME8569_1439.ECDH1ME8569_3827,iECD_1391.ECD_03844,iECH74115_1262.ECH74115_5419,iECIAI1_1343.ECIAI1_4167,iECO103_1326.ECO103_4715,iECOK1_1307.ECOK1_4431,iECS88_1305.ECS88_4414,iECSE_1348.ECSE_4252,iETEC_1333.ETEC_4227,iEcE24377_1341.EcE24377A_4498,iEcHS_1320.EcHS_A4193,iEcolC_1368.EcolC_4057,iSbBS512_1146.SbBS512_E4445,iUMN146_1321.UM146_20050,iUMNK88_1353.UMNK88_4797,iUTI89_1310.UTI89_C4550,iY75_1357.Y75_RS17255 Bacteria 47JI3@768503,4NDY8@976,COG0548@1,COG0548@2 NA|NA|NA E Belongs to the acetylglutamate kinase family. ArgB subfamily MAG.T22.3_01769 1239962.C943_02570 1.9e-175 621.7 Cytophagia argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.11,2.1.3.3,2.1.3.9 ko:K00611,ko:K09065,ko:K13043 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01398,R07245,R08937 RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 47JPH@768503,4NEYX@976,COG0078@1,COG0078@2 NA|NA|NA E Belongs to the ATCase OTCase family MAG.T22.3_01770 1239962.C943_02569 1.2e-200 705.7 Cytophagia argD 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 47JQP@768503,4NE0Z@976,COG4992@1,COG4992@2 NA|NA|NA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family MAG.T22.3_01771 1239962.C943_02568 2.1e-177 628.2 Cytophagia argC 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 Bacteria 47JNG@768503,4NEQR@976,COG0002@1,COG0002@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde MAG.T22.3_01772 1239962.C943_02567 8.6e-226 789.3 Cytophagia argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47JNE@768503,4NE3R@976,COG0137@1,COG0137@2 NA|NA|NA E argininosuccinate synthase MAG.T22.3_01773 1239962.C943_02566 7e-124 449.9 Cytophagia 2.3.1.178,2.3.1.57,2.3.1.82 ko:K00657,ko:K06718,ko:K18816 ko00260,ko00330,ko01100,ko01120,ko04216,map00260,map00330,map01100,map01120,map04216 M00033,M00135 R01154,R06978 RC00004,RC00096 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 47JY1@768503,4PKMC@976,COG1670@1,COG1670@2 NA|NA|NA J acetyltransferase MAG.T22.3_01775 1239962.C943_02564 2.2e-232 811.2 Cytophagia Bacteria 47KCX@768503,4NF4G@976,COG0520@1,COG0520@2 NA|NA|NA E PFAM aminotransferase class V MAG.T22.3_01776 1239962.C943_02563 1.1e-187 662.5 Cytophagia clgR GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006109,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009268,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009987,GO:0010447,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0010675,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031347,GO:0031348,GO:0032268,GO:0032502,GO:0033554,GO:0035821,GO:0040007,GO:0042176,GO:0043207,GO:0043565,GO:0043620,GO:0044003,GO:0044110,GO:0044111,GO:0044114,GO:0044115,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060255,GO:0061136,GO:0062012,GO:0065007,GO:0075136,GO:0080090,GO:0080134,GO:0085016,GO:0090062,GO:0097159,GO:1901363,GO:1902680,GO:1902882,GO:1903050,GO:1903362,GO:1903506,GO:1903508,GO:2000112,GO:2001141 ko:K02806 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 Bacteria 47S6J@768503,4NESH@976,COG1396@1,COG1396@2,COG3177@1,COG3177@2 NA|NA|NA K Fic/DOC family MAG.T22.3_01777 1239962.C943_02562 3.1e-122 444.5 Cytophagia dsb 5.3.4.1 ko:K01829 ko00000,ko01000 Bacteria 47NV7@768503,4NJ3N@976,COG2761@1,COG2761@2 NA|NA|NA Q dithiol-disulfide isomerase involved in polyketide biosynthesis MAG.T22.3_01778 1239962.C943_02560 5.3e-72 277.3 Cytophagia ko:K03892 ko00000,ko03000 Bacteria 47UMU@768503,4NS23@976,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional regulator MAG.T22.3_01779 1239962.C943_02559 2.9e-260 904.0 Cytophagia Bacteria 2E99W@1,333HY@2,47WUH@768503,4NXB1@976 NA|NA|NA MAG.T22.3_01780 1239962.C943_02558 3.5e-74 284.3 Cytophagia wxcM Bacteria 47R0Y@768503,4NQ4K@976,COG0662@1,COG0662@2 NA|NA|NA G WxcM-like, C-terminal MAG.T22.3_01781 1239962.C943_02557 2.1e-141 508.4 Cytophagia Bacteria 47PZH@768503,4NNZU@976,COG1196@1,COG1196@2 NA|NA|NA D Methyltransferase FkbM domain MAG.T22.3_01783 1239962.C943_01582 2.9e-152 544.7 Cytophagia Bacteria 47RN8@768503,4NECI@976,COG3146@1,COG3146@2 NA|NA|NA S Protein conserved in bacteria MAG.T22.3_01784 1239962.C943_01581 1.7e-117 428.7 Cytophagia Bacteria 2EBB5@1,335BV@2,47WJ2@768503,4NUQ0@976 NA|NA|NA MAG.T22.3_01787 1239962.C943_01578 6.6e-201 706.4 Cytophagia vioA GO:0005575,GO:0005576,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0075136,GO:0098771 2.6.1.33 ko:K13308,ko:K20429 ko00523,ko01130,map00523,map01130 M00797 R02773 RC00006,RC00781 ko00000,ko00001,ko00002,ko01000 Bacteria 47KCG@768503,4NGI4@976,COG0399@1,COG0399@2 NA|NA|NA E Belongs to the DegT DnrJ EryC1 family MAG.T22.3_01788 1239962.C943_01577 7.2e-67 260.4 Cytophagia 2.3.1.18 ko:K00633 ko00000,ko01000 Bacteria 47VD2@768503,4NNTF@976,COG0110@1,COG0110@2 NA|NA|NA S Bacterial transferase hexapeptide (six repeats) MAG.T22.3_01789 1239962.C943_01576 8.6e-145 519.6 Cytophagia ko:K01992,ko:K09690 ko02010,map02010 M00250,M00254 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.103 Bacteria 47NFE@768503,4NF36@976,COG1682@1,COG1682@2 NA|NA|NA GM PFAM ABC-2 type transporter MAG.T22.3_01790 1120968.AUBX01000013_gene3490 5.4e-138 497.7 Cytophagia 3.6.3.38 ko:K01990,ko:K09689,ko:K09691 ko02010,map02010 M00249,M00250,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.101,3.A.1.103 Bacteria 47JN7@768503,4NEDM@976,COG1134@1,COG1134@2 NA|NA|NA GM ABC-type polysaccharide polyol phosphate transport system ATPase component MAG.T22.3_01791 485918.Cpin_5773 2.5e-47 196.1 Sphingobacteriia Bacteria 1IXGB@117747,4NR55@976,COG2227@1,COG2227@2 NA|NA|NA H Methionine biosynthesis protein MetW MAG.T22.3_01792 1137281.D778_02597 8.1e-59 233.8 Bacteroidetes bioC 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 Bacteria 4PNUQ@976,COG2227@1,COG2227@2 NA|NA|NA H Methyltransferase domain MAG.T22.3_01793 1120968.AUBX01000013_gene3491 3.1e-76 292.4 Cytophagia ko:K16703 ko00000,ko01000,ko01003 GT4 Bacteria 47VCU@768503,4NE0U@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.3_01794 1239962.C943_01572 1.7e-165 588.6 Bacteria Bacteria COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase, family 2 MAG.T22.3_01795 72019.SARC_03505T0 1.6e-18 100.1 Opisthokonta Opisthokonta 2CY1A@1,2S19M@2759,3A5D1@33154 NA|NA|NA MAG.T22.3_01796 1239962.C943_01570 9.6e-180 636.0 Cytophagia GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016740,GO:0016757,GO:0030312,GO:0044464,GO:0071944 Bacteria 47M2Y@768503,4NQNJ@976,COG0463@1,COG0463@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T22.3_01797 1239962.C943_01569 1.1e-169 602.4 Bacteroidetes Bacteria 4NU2D@976,COG1215@1,COG1215@2 NA|NA|NA M Capsular biosynthesis protein CpsI MAG.T22.3_01798 1239962.C943_01568 1.8e-164 585.1 Cytophagia Bacteria 47S91@768503,4NVFC@976,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 MAG.T22.3_01799 1239962.C943_01567 2.2e-163 581.6 Cytophagia 2.7.8.14,2.7.8.47 ko:K12988,ko:K18704 R11614,R11621 ko00000,ko01000,ko01003,ko01005 GT2 Bacteria 47SBU@768503,4PMY4@976,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 2 MAG.T22.3_01800 1239962.C943_01566 9.1e-161 572.8 Cytophagia Bacteria 47RU5@768503,4PKGS@976,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 MAG.T22.3_01801 1239962.C943_01565 1.7e-180 638.6 Cytophagia cps4G Bacteria 47XD3@768503,4NG90@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase 4-like domain MAG.T22.3_01802 1239962.C943_01564 3.7e-178 630.9 Cytophagia ko:K00786 ko00000,ko01000 Bacteria 47VV4@768503,4PI5F@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 MAG.T22.3_01803 1239962.C943_01563 2.1e-211 741.5 Cytophagia Bacteria 2DBB7@1,2Z85R@2,47RTY@768503,4NJNG@976 NA|NA|NA MAG.T22.3_01804 1239962.C943_00423 0.0 1207.2 Cytophagia Bacteria 47P48@768503,4NI65@976,COG4585@1,COG4585@2 NA|NA|NA T histidine kinase dimerisation and phosphoacceptor region MAG.T22.3_01805 1239962.C943_00424 3.2e-107 394.4 Cytophagia Bacteria 47QM3@768503,4NMTW@976,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon MAG.T22.3_01806 1239962.C943_00425 0.0 1314.7 Cytophagia Bacteria 47NSK@768503,4NG7T@976,COG3533@1,COG3533@2 NA|NA|NA S Beta-L-arabinofuranosidase, GH127 MAG.T22.3_01807 1123277.KB893195_gene5663 2.1e-13 82.0 Cytophagia susB GO:0000272,GO:0003674,GO:0003824,GO:0004339,GO:0004553,GO:0004558,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015926,GO:0016020,GO:0016052,GO:0016787,GO:0016798,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:0090599,GO:1901575 3.2.1.20,3.2.1.3 ko:K01187,ko:K21574 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R01790,R01791,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 GH31,GH97 Bacteria 47JIF@768503,4NEWC@976,COG1082@1,COG1082@2 NA|NA|NA G Glycoside hydrolase 97 MAG.T22.3_01808 929562.Emtol_0710 1.7e-213 748.8 Cytophagia 3.2.1.3 ko:K21574 ko00500,ko01100,map00500,map01100 R01790,R01791 ko00000,ko00001,ko01000 GH97 Bacteria 47Y9E@768503,4PKIH@976,COG3023@1,COG3023@2 NA|NA|NA V PFAM Glycoside hydrolase 97 MAG.T22.3_01809 1239962.C943_00426 1.2e-120 439.5 Bacteria ko:K15546 ko00000,ko03000 Bacteria COG1680@1,COG1680@2,COG1813@1,COG1813@2 NA|NA|NA K peptidyl-tyrosine sulfation MAG.T22.3_01810 1239962.C943_04359 3.7e-224 783.9 Cytophagia trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20,5.3.1.24 ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03509 RC00209,RC00210,RC00700,RC00701,RC00945,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 47KSV@768503,4NDWP@976,COG0133@1,COG0133@2 NA|NA|NA E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine MAG.T22.3_01811 1239962.C943_04358 1.1e-115 422.5 Cytophagia trpF GO:0000162,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48,4.2.1.160,4.2.1.20,5.3.1.24 ko:K01696,ko:K01817,ko:K13498,ko:K22100 ko00260,ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map00790,map01100,map01110,map01130,map01230 M00023,M00840 R00674,R02340,R02722,R03508,R03509,R11072 RC00209,RC00210,RC00700,RC00701,RC00944,RC00945,RC02868,RC03343 ko00000,ko00001,ko00002,ko01000 iJN678.trpF,iPC815.YPO2205,iSBO_1134.SBO_1804,iSDY_1059.SDY_1330 Bacteria 47N69@768503,4NNQ1@976,COG0135@1,COG0135@2 NA|NA|NA E Belongs to the TrpF family MAG.T22.3_01812 1239962.C943_04357 2.1e-138 498.4 Cytophagia trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 47JRX@768503,4NFJT@976,COG0134@1,COG0134@2 NA|NA|NA E Belongs to the TrpC family MAG.T22.3_01813 1239962.C943_04356 6.7e-187 659.8 Cytophagia trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 47KKR@768503,4NH2J@976,COG0547@1,COG0547@2 NA|NA|NA E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) MAG.T22.3_01814 1239962.C943_04355 3.5e-92 344.4 Cytophagia trpG 2.4.2.18,2.6.1.85,4.1.3.27 ko:K01658,ko:K01664,ko:K13497 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01073,R01716 RC00010,RC00440,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 47JZQ@768503,4NE4I@976,COG0512@1,COG0512@2 NA|NA|NA EH TIGRFAM glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase MAG.T22.3_01815 926556.Echvi_2505 8.3e-40 169.9 Cytophagia 2.6.1.102 ko:K13010 ko00520,map00520 R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 47SM9@768503,4NSX7@976,COG0399@1,COG0399@2 NA|NA|NA M 23S rRNA-intervening sequence protein MAG.T22.3_01816 1239962.C943_04353 1.8e-254 884.8 Cytophagia trpE GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 47JMA@768503,4NFQ5@976,COG0147@1,COG0147@2 NA|NA|NA EH Anthranilate synthase component I, N terminal region MAG.T22.3_01817 1305737.JAFX01000001_gene182 1.5e-22 111.7 Cytophagia Bacteria 2EEII@1,338CF@2,47S4M@768503,4NV7G@976 NA|NA|NA MAG.T22.3_01818 1239962.C943_04350 4.6e-68 263.8 Cytophagia Bacteria 2BK9M@1,332MM@2,47V21@768503,4NX52@976 NA|NA|NA MAG.T22.3_01819 1239962.C943_04349 0.0 1429.8 Cytophagia ppsA 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 Bacteria 47JHD@768503,4NEHE@976,COG0574@1,COG0574@2,COG1080@1,COG1080@2 NA|NA|NA G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate MAG.T22.3_01820 1239962.C943_04348 3.8e-142 510.8 Cytophagia Bacteria 28PP0@1,2ZCBH@2,47PIT@768503,4NND0@976 NA|NA|NA MAG.T22.3_01821 866536.Belba_3413 3.5e-19 100.9 Cytophagia Bacteria 2DXJY@1,345BS@2,47VRX@768503,4P5NM@976 NA|NA|NA MAG.T22.3_01822 1239962.C943_04343 9.9e-141 506.1 Cytophagia wza ko:K01991 ko02026,map02026 ko00000,ko00001,ko02000 1.B.18 Bacteria 47Q2A@768503,4NFXJ@976,COG1596@1,COG1596@2 NA|NA|NA M Polysaccharide biosynthesis/export protein MAG.T22.3_01823 1239962.C943_04342 0.0 1517.3 Cytophagia wzc GO:0000271,GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016301,GO:0016310,GO:0016462,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0036211,GO:0038083,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046377,GO:0046777,GO:0071704,GO:0071944,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 ko:K16692 ko00000,ko01000,ko01001 Bacteria 47JQC@768503,4NEXU@976,COG0489@1,COG0489@2,COG3206@1,COG3206@2 NA|NA|NA DM TIGRFAM capsular exopolysaccharide family MAG.T22.3_01824 866536.Belba_0947 2.2e-39 169.1 Bacteria Bacteria 2EAXT@1,334YV@2 NA|NA|NA MAG.T22.3_01825 768671.ThimaDRAFT_0306 1.2e-14 85.5 Chromatiales dndA 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1MU1C@1224,1RNCD@1236,1WXTN@135613,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class-V MAG.T22.3_01826 1239962.C943_02775 0.0 1431.8 Cytophagia relA 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 Bacteria 47JQ8@768503,4NESY@976,COG0317@1,COG0317@2 NA|NA|NA KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance MAG.T22.3_01828 1239962.C943_02774 2.7e-236 824.3 Cytophagia tig ko:K03545 ko00000 Bacteria 47KTD@768503,4NE99@976,COG0544@1,COG0544@2 NA|NA|NA O Trigger factor MAG.T22.3_01829 1239962.C943_02773 2.9e-122 444.5 Cytophagia clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 47K60@768503,4NE20@976,COG0740@1,COG0740@2 NA|NA|NA OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins MAG.T22.3_01830 1239962.C943_02772 8.4e-218 762.7 Cytophagia clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 47JDR@768503,4NE1B@976,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP MAG.T22.3_01831 1239962.C943_02771 8e-196 689.9 Cytophagia lpxB GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 GT19 Bacteria 47JDC@768503,4NDW3@976,COG0763@1,COG0763@2 NA|NA|NA M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T22.3_01832 1239962.C943_02770 2e-28 131.0 Cytophagia Bacteria 2EGC0@1,331VR@2,47S8W@768503,4NWM2@976 NA|NA|NA MAG.T22.3_01833 1239962.C943_02769 4.2e-56 223.8 Cytophagia Bacteria 47R6I@768503,4NS6J@976,COG2315@1,COG2315@2 NA|NA|NA S YjbR MAG.T22.3_01834 1239962.C943_02768 4.9e-154 550.4 Cytophagia gtsA 3.6.3.30,3.6.3.55 ko:K02010,ko:K02049,ko:K02068,ko:K02071,ko:K06857,ko:K10112 ko02010,map02010 M00186,M00188,M00190,M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00211,M00238,M00491,M00602,M00605,M00606 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1,3.A.1.10,3.A.1.16,3.A.1.17,3.A.1.24,3.A.1.6.2,3.A.1.6.4 Bacteria 47N5M@768503,4NEZ6@976,COG3842@1,COG3842@2 NA|NA|NA E Belongs to the ABC transporter superfamily MAG.T22.3_01836 1239962.C943_02765 2.4e-92 344.7 Cytophagia slyD 5.2.1.8 ko:K03775 ko00000,ko01000,ko03110 Bacteria 47QER@768503,4NM29@976,COG1047@1,COG1047@2 NA|NA|NA O Peptidyl-prolyl cis-trans isomerase MAG.T22.3_01837 1189612.A33Q_3759 3.1e-18 97.8 Cytophagia Bacteria 2FEI1@1,346HI@2,47W1P@768503,4P53H@976 NA|NA|NA MAG.T22.3_01838 1239962.C943_02763 0.0 1846.2 Cytophagia leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 47MI0@768503,4NE5K@976,COG0495@1,COG0495@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family MAG.T22.3_01839 1239962.C943_02762 4.9e-184 650.2 Bacteroidetes ko:K12976 ko00000,ko01000,ko01005 Bacteria 4PNNP@976,COG3637@1,COG3637@2 NA|NA|NA M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety MAG.T22.3_01840 1239962.C943_02760 1.8e-300 1037.7 Cytophagia yhcX ko:K11206 ko00000,ko01000 Bacteria 47KHI@768503,4NEAQ@976,COG0388@1,COG0388@2 NA|NA|NA S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase MAG.T22.3_01841 1239962.C943_02759 0.0 1078.9 Cytophagia ycbB ko:K21470 ko00000,ko01002,ko01011 Bacteria 47MU1@768503,4NH3J@976,COG2989@1,COG2989@2 NA|NA|NA T L,D-transpeptidase catalytic domain MAG.T22.3_01842 1239962.C943_02758 5.6e-124 450.3 Cytophagia FN0914 Bacteria 47NYB@768503,4NNX7@976,COG1376@1,COG1376@2 NA|NA|NA S L,D-transpeptidase catalytic domain MAG.T22.3_01843 1239962.C943_02757 1.6e-75 288.5 Cytophagia sscR 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 47PQ5@768503,4NNIS@976,COG0720@1,COG0720@2 NA|NA|NA H PFAM 6-pyruvoyl tetrahydropterin synthase MAG.T22.3_01844 1239962.C943_02756 4.3e-121 440.7 Cytophagia folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R03503,R04639,R05046,R05048 RC00002,RC00017,RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv3609c Bacteria 47MMS@768503,4NFC2@976,COG0302@1,COG0302@2 NA|NA|NA H TIGRFAM GTP cyclohydrolase I MAG.T22.3_01845 1239962.C943_02755 1.9e-113 415.2 Cytophagia Bacteria 47K99@768503,4NFXD@976,COG1028@1,COG1028@2 NA|NA|NA IQ COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) MAG.T22.3_01846 1048983.EL17_04100 3.4e-26 124.0 Cytophagia Bacteria 2DNHJ@1,32XJ8@2,47R4X@768503,4NU45@976 NA|NA|NA MAG.T22.3_01847 1239962.C943_02753 8.1e-73 279.6 Cytophagia Bacteria 2CB0R@1,34B5H@2,47VYR@768503,4P6PE@976 NA|NA|NA MAG.T22.3_01848 1239962.C943_02752 5.3e-110 403.7 Cytophagia ywrF Bacteria 47PFI@768503,4NG6I@976,COG1853@1,COG1853@2 NA|NA|NA S Flavin reductase like domain MAG.T22.3_01849 1239962.C943_02751 3.3e-186 657.5 Cytophagia ko:K07577 ko00000 Bacteria 47JDM@768503,4NFN7@976,COG1236@1,COG1236@2 NA|NA|NA J exonuclease of the beta-lactamase fold involved in RNA processing MAG.T22.3_01850 1239962.C943_02750 1.3e-171 609.0 Cytophagia php ko:K07048 ko00000 Bacteria 47MZ3@768503,4NG0K@976,COG1735@1,COG1735@2 NA|NA|NA S Phosphotriesterase family MAG.T22.3_01851 866536.Belba_3086 1e-13 82.4 Bacteroidetes Bacteria 2ERUU@1,33JE1@2,4NZ11@976 NA|NA|NA MAG.T22.3_01852 1239962.C943_02747 6.1e-168 596.7 Cytophagia mrr ko:K07448 ko00000,ko02048 Bacteria 47QBY@768503,4NG35@976,COG1715@1,COG1715@2 NA|NA|NA V Mrr N-terminal domain MAG.T22.3_01853 1239962.C943_02746 1.6e-296 1024.6 Cytophagia guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 ko:K01951,ko:K03790 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002,ko03009 iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833 Bacteria 47JG6@768503,4NESX@976,COG0518@1,COG0518@2,COG0519@1,COG0519@2 NA|NA|NA F Catalyzes the synthesis of GMP from XMP MAG.T22.3_01855 1239962.C943_02743 1.7e-221 775.0 Cytophagia pyrC GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 47KKP@768503,4NDUZ@976,COG0044@1,COG0044@2 NA|NA|NA F TIGRFAM dihydroorotase, multifunctional complex type MAG.T22.3_01856 1239962.C943_02742 2.1e-88 331.6 Cytophagia Bacteria 2EVP8@1,33P37@2,47T57@768503,4NZKR@976 NA|NA|NA S Protein of unknown function (DUF4199) MAG.T22.3_01857 1239962.C943_02741 1.9e-87 328.6 Cytophagia Bacteria 29S8X@1,30DDE@2,47RMJ@768503,4NRBB@976 NA|NA|NA S Protein of unknown function (DUF4199) MAG.T22.3_01858 1239962.C943_02740 4e-181 640.6 Cytophagia arnC 2.4.1.83,2.4.2.53 ko:K00721,ko:K10012,ko:K20534 ko00510,ko00520,ko01100,ko01503,map00510,map00520,map01100,map01503 M00721,M00761 R01009,R07661 RC00005,RC02954 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko02000 4.D.2.1.8,4.D.2.1.9 GT2 Bacteria 47XY0@768503,4PKF3@976,COG1215@1,COG1215@2 NA|NA|NA M glycosyl transferase family 2 MAG.T22.3_01859 1239962.C943_02739 3.6e-174 617.5 Cytophagia exoA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K16557 ko00000,ko01000,ko01003 GT2 Bacteria 47MX1@768503,4PKBU@976,COG1215@1,COG1215@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T22.3_01860 1239962.C943_02738 1.8e-144 518.5 Cytophagia rebM Bacteria 47K6K@768503,4NE6P@976,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase domain MAG.T22.3_01861 1239962.C943_02737 1.3e-268 931.8 Cytophagia Bacteria 47KVY@768503,4NGXM@976,COG1538@1,COG1538@2 NA|NA|NA MU PFAM Outer membrane efflux protein MAG.T22.3_01862 1239962.C943_02736 2.8e-27 127.1 Cytophagia Bacteria 47S1G@768503,4NXSU@976,COG4877@1,COG4877@2 NA|NA|NA MAG.T22.3_01863 1239962.C943_02735 4.4e-91 340.5 Cytophagia Bacteria 2E30A@1,32Y0V@2,47RZP@768503,4NPVG@976 NA|NA|NA MAG.T22.3_01864 1189612.A33Q_1731 5e-31 141.0 Cytophagia Bacteria 2BUJ7@1,32PVK@2,47V2S@768503,4PB2W@976 NA|NA|NA MAG.T22.3_01865 1239962.C943_02733 1.8e-148 531.9 Cytophagia f42a Bacteria 47JW8@768503,4NEBV@976,COG0330@1,COG0330@2 NA|NA|NA O membrane protease MAG.T22.3_01866 866536.Belba_3075 3.3e-12 77.4 Cytophagia Bacteria 2EMVS@1,33FI0@2,47WMX@768503,4NYAD@976 NA|NA|NA MAG.T22.3_01867 756067.MicvaDRAFT_1605 5.5e-19 100.5 Oscillatoriales ko:K07171 ko00000,ko01000,ko02048 Bacteria 1G891@1117,1HHMA@1150,COG2337@1,COG2337@2 NA|NA|NA T PemK-like, MazF-like toxin of type II toxin-antitoxin system MAG.T22.3_01868 1239962.C943_02732 7.9e-129 466.5 Cytophagia Bacteria 47MF7@768503,4NEAI@976,COG1028@1,COG1028@2 NA|NA|NA IQ TIGRFAM 3-oxoacyl-(acyl-carrier-protein) reductase MAG.T22.3_01869 1189612.A33Q_1736 8.8e-27 125.9 Cytophagia ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 47RTX@768503,4NTHD@976,COG0614@1,COG0614@2 NA|NA|NA P PD-(D/E)XK nuclease superfamily MAG.T22.3_01871 1239962.C943_02730 3.3e-261 907.1 Cytophagia lpdA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47JS2@768503,4NDVC@976,COG1249@1,COG1249@2 NA|NA|NA C dihydrolipoamide dehydrogenase MAG.T22.3_01872 866536.Belba_1844 2.7e-70 271.6 Cytophagia ko:K03088 ko00000,ko03021 Bacteria 47QEF@768503,4NMIY@976,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T22.3_01873 866536.Belba_1845 4.6e-90 337.8 Cytophagia Bacteria 47M55@768503,4NI2H@976,COG5343@1,COG5343@2 NA|NA|NA S PFAM Anti-sigma-K factor RskA MAG.T22.3_01875 1239962.C943_02729 1.2e-51 209.1 Cytophagia Bacteria 2CH3Z@1,32RP9@2,47PY7@768503,4NQUA@976 NA|NA|NA S Protein of unknown function (DUF2721) MAG.T22.3_01876 1239962.C943_02727 1.2e-183 649.0 Cytophagia ltaA 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 Bacteria 47KXF@768503,4NEIH@976,COG2008@1,COG2008@2 NA|NA|NA E Threonine aldolase MAG.T22.3_01878 1123057.P872_22850 6.6e-82 311.2 Cytophagia Bacteria 47UY8@768503,4P3DZ@976,COG3391@1,COG3391@2 NA|NA|NA S 6-bladed beta-propeller MAG.T22.3_01879 1239962.C943_03263 6.3e-180 636.7 Cytophagia ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 Bacteria 47MJM@768503,4NHJH@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.3_01880 1239962.C943_03264 0.0 1763.4 Cytophagia mdtC ko:K03296 ko00000 2.A.6.2 Bacteria 47M3R@768503,4NE3H@976,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T22.3_01881 1239962.C943_03265 0.0 1901.7 Cytophagia Bacteria 47NK8@768503,4NH0G@976,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T22.3_01882 1385420.FRA_34c06160 2.8e-11 73.6 Thiotrichales yoeB ko:K19158 ko00000,ko01000,ko02048 Bacteria 1MZBP@1224,1S99Z@1236,4617I@72273,COG4115@1,COG4115@2 NA|NA|NA S TIGRFAM toxin-antitoxin system, toxin component, Txe YoeB family MAG.T22.3_01883 929556.Solca_4102 1.6e-28 131.7 Sphingobacteriia yefM 2.3.1.15 ko:K08591,ko:K19158,ko:K19159 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004,ko02048 Bacteria 1IYWV@117747,4PIY5@976,COG2161@1,COG2161@2 NA|NA|NA D Antitoxin Phd_YefM, type II toxin-antitoxin system MAG.T22.3_01884 1120951.AUBG01000006_gene538 2.8e-34 151.8 Bacteroidetes Bacteria 2E4JM@1,32ZEQ@2,4NWD9@976 NA|NA|NA MAG.T22.3_01885 760192.Halhy_3922 9.8e-53 213.4 Bacteroidetes ko:K06919 ko00000 Bacteria 4NP4G@976,COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score MAG.T22.3_01886 1123277.KB893195_gene5682 7.7e-90 337.4 Cytophagia ko:K09144 ko00000 Bacteria 47XQK@768503,4NMIN@976,COG2253@1,COG2253@2 NA|NA|NA S Nucleotidyl transferase AbiEii toxin, Type IV TA system MAG.T22.3_01888 1239962.C943_03328 3.8e-42 177.2 Bacteroidetes 1.5.1.40 ko:K06988 ko00000,ko01000 Bacteria 4NSV0@976,COG1359@1,COG1359@2 NA|NA|NA S Antibiotic biosynthesis monooxygenase MAG.T22.3_01889 1239962.C943_03329 2.3e-139 501.5 Cytophagia fjo14 ko:K22205 ko00000,ko01000 Bacteria 47PS4@768503,4NG9Y@976,COG1912@1,COG1912@2 NA|NA|NA S S-adenosyl-l-methionine hydroxide adenosyltransferase MAG.T22.3_01890 1189612.A33Q_2095 7.5e-159 566.6 Cytophagia phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06217 ko00000 Bacteria 47JUG@768503,4NDYV@976,COG1702@1,COG1702@2 NA|NA|NA T Phosphate starvation-inducible protein PhoH MAG.T22.3_01891 1239962.C943_03332 3.7e-73 280.8 Cytophagia MA20_28330 3.5.4.33,4.4.1.8 ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941,R10223 RC00056,RC00069,RC00382,RC00477,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007,ko03016 Bacteria 47Q2T@768503,4NT5M@976,COG2153@1,COG2153@2 NA|NA|NA S PFAM Acetyltransferase (GNAT) family MAG.T22.3_01892 1239962.C943_03333 9.9e-89 332.8 Bacteroidetes Bacteria 2DM69@1,31WI4@2,4NR2C@976 NA|NA|NA MAG.T22.3_01893 1239962.C943_03335 2e-288 998.0 Cytophagia comEC ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 47K9X@768503,4NEJH@976,COG0658@1,COG0658@2 NA|NA|NA S TIGRFAM ComEC Rec2-related protein MAG.T22.3_01894 1239962.C943_03336 1.1e-136 492.7 Cytophagia liuC 4.2.1.17,4.2.1.18,4.2.1.57 ko:K01692,ko:K13766,ko:K13779 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00036,M00087 R02085,R03026,R03045,R03493,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC00941,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02416 ko00000,ko00001,ko00002,ko01000 Bacteria 47MCZ@768503,4NI32@976,COG1024@1,COG1024@2 NA|NA|NA I Belongs to the enoyl-CoA hydratase isomerase family MAG.T22.3_01895 1239962.C943_03337 0.0 1241.5 Cytophagia recQ2 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 47M73@768503,4NEFD@976,COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase RecQ MAG.T22.3_01896 1239962.C943_03338 5.3e-104 383.6 Cytophagia Bacteria 2E7JF@1,3321M@2,47SEY@768503,4NWMH@976 NA|NA|NA MAG.T22.3_01897 1239962.C943_03339 7.7e-97 359.8 Cytophagia Bacteria 47PUZ@768503,4NNJ5@976,COG1051@1,COG1051@2 NA|NA|NA F pfam nudix MAG.T22.3_01898 1239962.C943_03340 2.1e-73 281.6 Cytophagia ko:K07107 ko00000,ko01000 Bacteria 47R01@768503,4NQ3I@976,COG0824@1,COG0824@2 NA|NA|NA S Thioesterase-like superfamily MAG.T22.3_01899 1239962.C943_03341 2.7e-46 192.2 Cytophagia Bacteria 47K50@768503,4NI2C@976,COG0457@1,COG0457@2 NA|NA|NA S Pfam Tetratricopeptide repeat MAG.T22.3_01900 1239962.C943_03342 1.2e-172 612.5 Cytophagia sua5 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 47KX9@768503,4NF5U@976,COG0009@1,COG0009@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine MAG.T22.3_01901 1239962.C943_03343 1.6e-219 768.5 Cytophagia pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47K8V@768503,4NFW2@976,COG0126@1,COG0126@2 NA|NA|NA G Belongs to the phosphoglycerate kinase family MAG.T22.3_01904 224325.AF_1627 3.6e-17 93.6 Euryarchaeota ko:K07729 ko00000,ko03000 Archaea 2Y089@28890,COG1476@1,arCOG01864@2157 NA|NA|NA K Transcriptional regulator MAG.T22.3_01906 1123057.P872_16810 6.5e-07 60.1 Cytophagia Bacteria 292QE@1,2ZQ87@2,47WZ5@768503,4P8R9@976 NA|NA|NA MAG.T22.3_01907 1239962.C943_03347 0.0 1534.6 Cytophagia 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 GH3 Bacteria 47NZE@768503,4NE90@976,COG1472@1,COG1472@2 NA|NA|NA G Glycosyl hydrolase family 3 C-terminal domain MAG.T22.3_01908 1239962.C943_03349 0.0 2246.1 Cytophagia ko:K09992 ko00000 Bacteria 47MAT@768503,4NDVK@976,COG2133@1,COG2133@2,COG3291@1,COG3291@2,COG3828@1,COG3828@2,COG4654@1,COG4654@2 NA|NA|NA CG Cytochrome c, class I MAG.T22.3_01909 1239962.C943_03351 3e-170 604.4 Bacteroidetes 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 4NFIH@976,COG0329@1,COG0329@2 NA|NA|NA EM Belongs to the DapA family MAG.T22.3_01910 1239962.C943_03352 2.6e-244 850.9 Cytophagia pepP GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 ko:K01262 ko00000,ko01000,ko01002 Bacteria 47MAV@768503,4NG40@976,COG0006@1,COG0006@2 NA|NA|NA E Belongs to the peptidase M24B family MAG.T22.3_01911 866536.Belba_1950 5.5e-22 110.2 Cytophagia Bacteria 2DQ14@1,334AM@2,47S0V@768503,4NWKX@976 NA|NA|NA MAG.T22.3_01912 1239962.C943_03354 4.4e-300 1036.6 Cytophagia polX ko:K02347,ko:K04477 ko00000,ko03400 Bacteria 47KZJ@768503,4NDX5@976,COG1387@1,COG1387@2,COG1796@1,COG1796@2 NA|NA|NA L PFAM PHP domain MAG.T22.3_01913 1239962.C943_03355 4e-66 257.3 Cytophagia Bacteria 47QAF@768503,4NNQG@976,COG2947@1,COG2947@2 NA|NA|NA S EVE domain MAG.T22.3_01914 1239962.C943_03356 4.3e-292 1010.0 Cytophagia Bacteria 28KQM@1,2ZA8D@2,47JWY@768503,4NH80@976 NA|NA|NA MAG.T22.3_01915 1239962.C943_03357 2.1e-61 241.5 Cytophagia Bacteria 2DZQQ@1,32VGE@2,47RKY@768503,4NTQG@976 NA|NA|NA S Transmembrane family 220, helix MAG.T22.3_01916 1239962.C943_03358 6.3e-142 510.0 Cytophagia Bacteria 47NID@768503,4NJE8@976,COG5507@1,COG5507@2 NA|NA|NA S NIPSNAP MAG.T22.3_01917 1239962.C943_03359 0.0 1895.2 Cytophagia gcvP GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016638,GO:0016642,GO:0030312,GO:0040007,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.4.4.2 ko:K00281,ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_3318 Bacteria 47K29@768503,4NEDE@976,COG0403@1,COG0403@2,COG1003@1,COG1003@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor MAG.T22.3_01918 1239962.C943_03360 2.7e-269 934.1 Cytophagia Bacteria 47M5P@768503,4NFDJ@976,COG2234@1,COG2234@2 NA|NA|NA S Peptidase family M28 MAG.T22.3_01919 1239962.C943_03361 4.7e-163 580.5 Bacteroidetes ko:K01250 ko00000,ko01000 Bacteria 4NQ07@976,COG1957@1,COG1957@2 NA|NA|NA F Inosine-uridine preferring nucleoside hydrolase MAG.T22.3_01920 1239962.C943_03362 2.6e-228 797.7 Cytophagia rodA ko:K05837 ko00000,ko03036 Bacteria 47JVQ@768503,4NDZD@976,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family MAG.T22.3_01921 1239962.C943_03363 0.0 1185.2 Cytophagia mrdA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011 iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604 Bacteria 47JSM@768503,4NE47@976,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding protein, dimerisation domain MAG.T22.3_01922 1239962.C943_03364 2.7e-73 281.6 Cytophagia mreD Bacteria 2AFDM@1,315DF@2,47R21@768503,4NQ5K@976 NA|NA|NA S rod shape-determining protein MreD MAG.T22.3_01923 1239962.C943_03365 2.7e-146 524.6 Cytophagia mreC ko:K03570 ko00000,ko03036 9.B.157.1 Bacteria 47KWQ@768503,4NF14@976,COG1792@1,COG1792@2 NA|NA|NA M Involved in formation and maintenance of cell shape MAG.T22.3_01924 1239962.C943_03366 3.4e-186 657.5 Cytophagia mreB ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 47JQ4@768503,4NETQ@976,COG1077@1,COG1077@2 NA|NA|NA D TIGRFAM cell shape determining protein, MreB Mrl family MAG.T22.3_01925 1239962.C943_03367 5.8e-77 293.5 Cytophagia rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 ko:K09748 ko00000,ko03009 Bacteria 47R9C@768503,4NQ32@976,COG0779@1,COG0779@2 NA|NA|NA S Required for maturation of 30S ribosomal subunits MAG.T22.3_01926 1239962.C943_03368 5.2e-226 790.0 Cytophagia nusA GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02600 ko00000,ko03009,ko03021 Bacteria 47KFI@768503,4NFGA@976,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination MAG.T22.3_01927 1239962.C943_03369 0.0 1738.8 Cytophagia infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K02519 ko00000,ko03012,ko03029 Bacteria 47KGB@768503,4NGP3@976,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex MAG.T22.3_01928 1239962.C943_03370 2e-241 841.3 Cytophagia 4.1.1.11,4.1.1.25 ko:K18933 ko00350,ko00410,ko00680,ko00770,ko01100,ko01110,map00350,map00410,map00680,map00770,map01100,map01110 R00489,R00736 RC00299 ko00000,ko00001,ko01000 Bacteria 47NFU@768503,4NGRW@976,COG0076@1,COG0076@2 NA|NA|NA E Pyridoxal-dependent decarboxylase conserved domain MAG.T22.3_01929 1239962.C943_03371 2.4e-130 471.5 Cytophagia aroE 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 Bacteria 47JZN@768503,4NEBJ@976,COG0169@1,COG0169@2 NA|NA|NA E PFAM Shikimate dehydrogenase substrate binding domain MAG.T22.3_01930 1239962.C943_03372 3.1e-162 577.8 Cytophagia ko:K08974 ko00000 Bacteria 47MKT@768503,4NFKI@976,COG2035@1,COG2035@2 NA|NA|NA S Domain of unknown function (DUF368) MAG.T22.3_01931 1239962.C943_03373 3.1e-144 517.7 Cytophagia yitD 4.4.1.19 ko:K08097 ko00680,ko01120,map00680,map01120 M00358 R07476 RC01799 ko00000,ko00001,ko00002,ko01000 Bacteria 47MRM@768503,4NEHT@976,COG1809@1,COG1809@2 NA|NA|NA S PFAM (2R)-phospho-3-sulfolactate synthase ComA MAG.T22.3_01932 1239962.C943_03374 3.5e-48 199.5 Cytophagia Bacteria 47M8A@768503,4NG1I@976,COG0457@1,COG0457@2 NA|NA|NA NU PFAM Tetratricopeptide repeat MAG.T22.3_01933 1239962.C943_03376 2e-172 611.7 Cytophagia 1.1.1.219 ko:K00091 ko00000,ko01000 Bacteria 47M93@768503,4NFZH@976,COG0451@1,COG0451@2 NA|NA|NA M PFAM NAD dependent epimerase dehydratase family MAG.T22.3_01934 1239962.C943_03377 2.3e-136 491.5 Cytophagia Bacteria 47PBY@768503,4NMUT@976,COG4464@1,COG4464@2 NA|NA|NA GM capsular polysaccharide biosynthesis protein MAG.T22.3_01935 1239962.C943_03378 1.1e-112 412.5 Cytophagia rfbC 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 47PQR@768503,4NNKW@976,COG1898@1,COG1898@2 NA|NA|NA M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose MAG.T22.3_01936 1239962.C943_03379 2.6e-225 787.7 Cytophagia hflX ko:K03665 ko00000,ko03009 Bacteria 47JGI@768503,4NF0P@976,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis MAG.T22.3_01937 1239962.C943_03380 5e-241 840.1 Cytophagia rsmF GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176,2.1.1.178 ko:K03500,ko:K11392 ko00000,ko01000,ko03009 Bacteria 47KID@768503,4NEV7@976,COG0144@1,COG0144@2,COG3270@1,COG3270@2 NA|NA|NA J RNA-binding PUA-like domain of methyltransferase RsmF MAG.T22.3_01938 1239962.C943_03381 2e-119 435.3 Bacteroidetes Bacteria 2DQVC@1,338X2@2,4NW3I@976 NA|NA|NA S CHAD domain MAG.T22.3_01939 1239962.C943_03382 2.2e-152 545.0 Cytophagia Bacteria 2FCNH@1,344RS@2,47VP6@768503,4P6MK@976 NA|NA|NA MAG.T22.3_01940 1239962.C943_03383 2.1e-157 561.6 Cytophagia coaE Bacteria 47JWV@768503,4NHPF@976,COG3662@1,COG3662@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2236) MAG.T22.3_01941 1239962.C943_03384 1.9e-109 401.7 Cytophagia ydjA Bacteria 47PFV@768503,4NMUE@976,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase family MAG.T22.3_01942 1239962.C943_03385 4.2e-92 344.0 Cytophagia Bacteria 47XVC@768503,4NRSP@976,COG2318@1,COG2318@2 NA|NA|NA S DinB family MAG.T22.3_01943 1239962.C943_03386 4.5e-103 380.6 Cytophagia gldD Bacteria 293VW@1,2ZRB2@2,47PUM@768503,4NMK7@976 NA|NA|NA S TIGRFAM gliding motility-associated lipoprotein GldD MAG.T22.3_01944 1239962.C943_03388 0.0 1141.3 Cytophagia putP Bacteria 47MV2@768503,4PKHI@976,COG0591@1,COG0591@2 NA|NA|NA E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family MAG.T22.3_01945 1239962.C943_03389 7.8e-175 619.8 Cytophagia mdsC 2.7.1.162,2.7.1.39 ko:K02204,ko:K13059 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771,R08962 RC00002,RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 47QCK@768503,4NH00@976,COG2334@1,COG2334@2 NA|NA|NA S Phosphotransferase enzyme family MAG.T22.3_01946 1239962.C943_03390 0.0 1255.7 Cytophagia dsbD 1.8.1.8 ko:K04084 ko00000,ko01000,ko03110 5.A.1.1 Bacteria 47JTC@768503,4NEW6@976,COG4232@1,COG4232@2 NA|NA|NA CO Cytochrome c biogenesis protein transmembrane region MAG.T22.3_01947 1239962.C943_03391 1.7e-262 911.4 Cytophagia dapE 3.5.1.16,3.5.1.18 ko:K01436,ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00669,R02734,R09107 RC00064,RC00090,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 47JN6@768503,4NFGE@976,COG0624@1,COG0624@2 NA|NA|NA E PFAM Peptidase family M20 M25 M40 MAG.T22.3_01948 1239962.C943_03392 2.9e-266 924.1 Cytophagia qor2 1.6.5.5,4.2.1.55,5.3.3.18 ko:K00344,ko:K15866,ko:K17865 ko00360,ko00630,ko00650,ko01120,ko01200,map00360,map00630,map00650,map01120,map01200 M00373 R03027,R09837,R09839 RC00004,RC00326,RC00831,RC02689,RC03003 ko00000,ko00001,ko00002,ko01000 Bacteria 47MCY@768503,4NEYW@976,COG0604@1,COG0604@2,COG2030@1,COG2030@2 NA|NA|NA C Zinc-binding dehydrogenase MAG.T22.3_01949 1239962.C943_03393 1.9e-208 731.5 Cytophagia 2.4.1.339,2.4.1.340,3.2.1.197 ko:K20885,ko:K21065 R11397,R11398,R11544 RC00049,RC02748 ko00000,ko01000 GH130 Bacteria 47MHY@768503,4NG7B@976,COG2152@1,COG2152@2 NA|NA|NA G beta-1,4-mannooligosaccharide phosphorylase MAG.T22.3_01950 1239962.C943_03394 1.4e-113 415.6 Cytophagia Bacteria 47U3P@768503,4NYCJ@976,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase domain MAG.T22.3_01951 1239962.C943_03395 1.7e-257 894.8 Cytophagia wcaJ ko:K03606 ko05111,map05111 ko00000,ko00001 Bacteria 47N5W@768503,4NER4@976,COG2148@1,COG2148@2 NA|NA|NA M sugar transferase MAG.T22.3_01952 1239962.C943_03396 1.2e-150 539.3 Cytophagia Bacteria 47QIC@768503,4NRKZ@976,COG2227@1,COG2227@2 NA|NA|NA H Methyltransferase domain MAG.T22.3_01953 388413.ALPR1_01845 1.9e-87 329.7 Cytophagia Bacteria 28JVJ@1,2Z9KI@2,47NTY@768503,4NDVQ@976 NA|NA|NA MAG.T22.3_01954 1239962.C943_03399 1.5e-141 508.8 Cytophagia ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.1.1.182,2.7.1.148 ko:K00919,ko:K02528,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634,R10716 RC00002,RC00003,RC01439,RC03257 ko00000,ko00001,ko00002,ko01000,ko02000,ko03009 3.A.1.29 iYO844.BSU00460 Bacteria 47JG4@768503,4NGFC@976,COG1947@1,COG1947@2 NA|NA|NA I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol MAG.T22.3_01955 1239962.C943_03400 0.0 1077.0 Cytophagia ilvD GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 Bacteria 47J9Q@768503,4NFHP@976,COG0129@1,COG0129@2 NA|NA|NA EG Belongs to the IlvD Edd family MAG.T22.3_01956 1239962.C943_03401 0.0 1102.0 Cytophagia ilvB 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 Bacteria 47UCT@768503,4NENG@976,COG0028@1,COG0028@2 NA|NA|NA H Thiamine pyrophosphate enzyme, central domain MAG.T22.3_01957 1239962.C943_03402 4.3e-86 323.9 Cytophagia ilvN GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 iAF1260.b3670,iAPECO1_1312.APECO1_2782,iB21_1397.B21_03496,iBWG_1329.BWG_3361,iE2348C_1286.E2348C_3985,iEC042_1314.EC042_4025,iECABU_c1320.ECABU_c41570,iECBD_1354.ECBD_0033,iECB_1328.ECB_03554,iECDH10B_1368.ECDH10B_3853,iECDH1ME8569_1439.ECDH1ME8569_3555,iECD_1391.ECD_03554,iECED1_1282.ECED1_4366,iECH74115_1262.ECH74115_5103,iECIAI1_1343.ECIAI1_3846,iECIAI39_1322.ECIAI39_4272,iECNA114_1301.ECNA114_3825,iECO111_1330.ECO111_4494,iECO26_1355.ECO26_4913,iECOK1_1307.ECOK1_4123,iECP_1309.ECP_3877,iECS88_1305.ECS88_4095,iECSE_1348.ECSE_3954,iECSF_1327.ECSF_3518,iECSP_1301.ECSP_4721,iECUMN_1333.ECUMN_4201,iECW_1372.ECW_m3968,iECs_1301.ECs4611,iEKO11_1354.EKO11_0033,iETEC_1333.ETEC_3964,iEcDH1_1363.EcDH1_0033,iEcE24377_1341.EcE24377A_4179,iEcHS_1320.EcHS_A3883,iEcSMS35_1347.EcSMS35_4037,iEcolC_1368.EcolC_0029,iG2583_1286.G2583_4464,iJO1366.b3670,iJR904.b3670,iLF82_1304.LF82_1110,iNRG857_1313.NRG857_18305,iPC815.YPO2294,iSFV_1184.SFV_3839,iSF_1195.SF3791,iSFxv_1172.SFxv_4123,iSSON_1240.SSON_3624,iS_1188.S3977,iUMN146_1321.UM146_18560,iUMNK88_1353.UMNK88_4479,iUTI89_1310.UTI89_C4226,iWFL_1372.ECW_m3968,iY75_1357.Y75_RS18770,iYL1228.KPN_04073,iZ_1308.Z5164,ic_1306.c4595 Bacteria 47K1H@768503,4NIDK@976,COG0440@1,COG0440@2 NA|NA|NA E TIGRFAM Acetolactate synthase, small subunit MAG.T22.3_01958 1239962.C943_03403 1.2e-196 692.2 Cytophagia ilvC GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 iEC042_1314.EC042_4152,iECABU_c1320.ECABU_c42560,iECED1_1282.ECED1_4460,iECO103_1326.ECO103_4390,iECO111_1330.ECO111_4600,iECO26_1355.ECO26_4812,iECP_1309.ECP_3967,iECSE_1348.ECSE_4057,iECUMN_1333.ECUMN_4300,iEcE24377_1341.EcE24377A_4285,iEcSMS35_1347.EcSMS35_4140,iIT341.HP0330,iLF82_1304.LF82_1103 Bacteria 47KF1@768503,4NFYV@976,COG0059@1,COG0059@2 NA|NA|NA EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate MAG.T22.3_01959 1239962.C943_03404 4.5e-280 969.9 Cytophagia leuA GO:0003674,GO:0003824,GO:0003852,GO:0003985,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046912,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 iSFV_1184.SFV_0066 Bacteria 47N2Y@768503,4NEIT@976,COG0119@1,COG0119@2 NA|NA|NA E Belongs to the alpha-IPM synthase homocitrate synthase family MAG.T22.3_01960 1239962.C943_03405 9.3e-272 942.2 Cytophagia leuC GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 iEcE24377_1341.EcE24377A_0075,iPC815.YPO0531,iSB619.SA_RS10700 Bacteria 47JAE@768503,4NG7E@976,COG0065@1,COG0065@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate MAG.T22.3_01961 1239962.C943_03406 1.3e-108 399.1 Cytophagia leuD 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 47NNG@768503,4NDVY@976,COG0066@1,COG0066@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate MAG.T22.3_01962 1239962.C943_03407 2.4e-308 1063.9 Cytophagia leuA2 2.3.1.182,2.3.3.13 ko:K01649,ko:K09011 ko00290,ko00620,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R01213,R07399 RC00004,RC00470,RC01205,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 47JWF@768503,4NF3N@976,COG0119@1,COG0119@2 NA|NA|NA E Belongs to the alpha-IPM synthase homocitrate synthase family MAG.T22.3_01963 1239962.C943_03408 2.4e-195 688.0 Cytophagia leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 47MDN@768503,4NEBE@976,COG0473@1,COG0473@2 NA|NA|NA CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate MAG.T22.3_01964 1123057.P872_12820 3.4e-103 381.7 Cytophagia ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 47VHE@768503,4P4Y8@976,COG4932@1,COG4932@2 NA|NA|NA M domain protein MAG.T22.3_01965 1239962.C943_03409 5.4e-128 463.8 Cytophagia truA 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 47Q6S@768503,4NG3N@976,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs MAG.T22.3_01966 1123057.P872_09470 6.7e-68 263.8 Cytophagia Bacteria 47PBC@768503,4NMRK@976,COG4319@1,COG4319@2 NA|NA|NA S Protein of unknown function (DUF2911) MAG.T22.3_01967 1239962.C943_03410 9.5e-152 542.7 Cytophagia fabI GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 47KZ9@768503,4NEVE@976,COG0623@1,COG0623@2 NA|NA|NA I Enoyl- acyl-carrier-protein reductase NADH MAG.T22.3_01968 1239962.C943_03411 5.3e-250 870.2 Cytophagia recN ko:K03631,ko:K07459 ko00000,ko03400 Bacteria 47JTP@768503,4NE3I@976,COG0497@1,COG0497@2 NA|NA|NA L May be involved in recombinational repair of damaged DNA MAG.T22.3_01969 1239962.C943_03412 2.5e-222 777.7 Cytophagia yliI 1.1.5.2 ko:K00117,ko:K21430 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 R06620 RC00066 ko00000,ko00001,ko01000 Bacteria 47KSC@768503,4NEZC@976,COG2133@1,COG2133@2 NA|NA|NA G PFAM Glucose Sorbosone dehydrogenase MAG.T22.3_01970 1239962.C943_03414 2.2e-207 728.0 Cytophagia Bacteria 47JT2@768503,4NG75@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase domain protein TIM barrel MAG.T22.3_01971 1239962.C943_03415 0.0 1607.4 Cytophagia clpB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030312,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0040007,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 ko:K03694,ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Bacteria 47KA7@768503,4NGEM@976,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE MAG.T22.3_01972 1239962.C943_03417 0.0 1950.6 Bacteroidetes Bacteria 4NDXU@976,COG0642@1,COG0784@1,COG0784@2,COG1807@1,COG1807@2,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T22.3_01973 1239962.C943_03418 1.2e-188 665.6 Cytophagia ykfB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 ko:K19802 R10938 RC03309 ko00000,ko01000 Bacteria 47K7T@768503,4NG8N@976,COG4948@1,COG4948@2 NA|NA|NA M mandelate racemase muconate lactonizing MAG.T22.3_01974 1239962.C943_03419 9.5e-283 978.8 Cytophagia Bacteria 47MSA@768503,4NDXH@976,COG2866@1,COG2866@2 NA|NA|NA E Zinc carboxypeptidase MAG.T22.3_01975 1239962.C943_03420 1.3e-145 522.3 Bacteroidetes Bacteria 2ETG7@1,33M02@2,4NXSR@976 NA|NA|NA MAG.T22.3_01976 1239962.C943_03421 0.0 1904.4 Cytophagia Bacteria 47JSW@768503,4NEIE@976,COG1629@1,COG1629@2,COG4771@2 NA|NA|NA P PFAM TonB-dependent Receptor Plug MAG.T22.3_01977 1239962.C943_03422 1e-255 889.0 Cytophagia Bacteria 47UGF@768503,4PKU5@976,COG3291@1,COG3291@2 NA|NA|NA S Pkd domain containing protein MAG.T22.3_01978 1239962.C943_03423 7.6e-172 609.8 Cytophagia moxR ko:K03924 ko00000,ko01000 Bacteria 47JEN@768503,4NDVZ@976,COG0714@1,COG0714@2 NA|NA|NA S PFAM ATPase family associated with various cellular activities (AAA) MAG.T22.3_01979 402612.FP0102 4.4e-19 100.5 Flavobacterium Bacteria 1IHQG@117743,2NXTR@237,4PGZR@976,COG3668@1,COG3668@2 NA|NA|NA S ParE toxin of type II toxin-antitoxin system, parDE MAG.T22.3_01980 402612.FP0103 6.7e-10 69.7 Flavobacterium Bacteria 1IDEP@117743,2A2CN@1,2NY5G@237,30QPN@2,4PCX2@976 NA|NA|NA MAG.T22.3_01981 1239962.C943_03425 0.0 1481.8 Cytophagia Bacteria 47JMU@768503,4NETM@976,COG1032@1,COG1032@2 NA|NA|NA C PFAM Radical SAM MAG.T22.3_01982 1107311.Q767_15530 1.9e-38 166.0 Flavobacterium Bacteria 1IDP2@117743,29BGN@1,2NYVX@237,2ZYF1@2,4PD54@976 NA|NA|NA MAG.T22.3_01983 1313421.JHBV01000153_gene974 3.2e-26 125.2 Bacteroidetes Bacteria 2BWR5@1,2ZUVQ@2,4P955@976 NA|NA|NA MAG.T22.3_01984 1239962.C943_03429 4.2e-107 394.0 Cytophagia rluE GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 ko:K06178,ko:K06181 ko00000,ko01000,ko03009 Bacteria 47PFZ@768503,4NM4U@976,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family MAG.T22.3_01985 1239962.C943_03432 1.2e-24 118.2 Cytophagia Bacteria 2CB74@1,33E9Q@2,47WE8@768503,4NXAI@976 NA|NA|NA MAG.T22.3_01986 1239962.C943_03433 2.8e-171 607.8 Cytophagia 3.5.1.105 ko:K03478 ko00000,ko01000 Bacteria 47MN2@768503,4NFY5@976,COG3394@1,COG3394@2 NA|NA|NA G YdjC-like protein MAG.T22.3_01987 1239962.C943_03434 2.4e-195 688.0 Cytophagia Bacteria 28M5H@1,2ZAJ9@2,47NNA@768503,4NESS@976 NA|NA|NA MAG.T22.3_01988 1239962.C943_03435 2.3e-96 358.2 Cytophagia Bacteria 28IPG@1,2Z8PF@2,47PUI@768503,4NP42@976 NA|NA|NA MAG.T22.3_01989 1239962.C943_03436 1.3e-292 1011.5 Cytophagia cry 4.1.99.3 ko:K01669 ko00000,ko01000,ko03400 Bacteria 47J9N@768503,4NDW0@976,COG0415@1,COG0415@2 NA|NA|NA L DNA photolyase MAG.T22.3_01990 1239962.C943_03437 2.3e-173 614.8 Cytophagia Bacteria 47N64@768503,4NHHT@976,COG0604@1,COG0604@2 NA|NA|NA C COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase MAG.T22.3_01991 1239962.C943_03438 4.5e-247 860.1 Bacteria Bacteria COG0346@1,COG0346@2 NA|NA|NA E lactoylglutathione lyase activity MAG.T22.3_01992 1239962.C943_03439 1.4e-133 482.3 Cytophagia Bacteria 47Y3M@768503,4PKUD@976,COG0596@1,COG0596@2 NA|NA|NA S Alpha/beta hydrolase family MAG.T22.3_01993 746697.Aeqsu_1493 4.2e-20 103.6 Bacteroidetes Bacteria 2A1D2@1,30PK3@2,4NW4I@976 NA|NA|NA S Protein of unknown function (DUF2442) MAG.T22.3_01994 1239962.C943_03441 0.0 1280.0 Cytophagia dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527 Bacteria 47JUB@768503,4NDY5@976,COG1154@1,COG1154@2 NA|NA|NA H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) MAG.T22.3_01995 1239962.C943_03442 2.5e-130 471.5 Cytophagia scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K05896 ko00000,ko03036 Bacteria 47MUR@768503,4NJQE@976,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves MAG.T22.3_01996 1239962.C943_03443 1.7e-193 681.8 Cytophagia mprF ko:K07027 ko00000,ko02000 4.D.2 Bacteria 47MPB@768503,4NIWG@976,COG0392@1,COG0392@2 NA|NA|NA S PFAM Uncharacterised protein family (UPF0104) MAG.T22.3_01997 1239962.C943_03444 0.0 1541.2 Cytophagia alr 5.1.1.1,6.3.2.10 ko:K01775,ko:K01929 ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502 R00401,R04573,R04617 RC00064,RC00141,RC00285 ko00000,ko00001,ko01000,ko01011 Bacteria 47JKP@768503,4NEXM@976,COG0770@1,COG0770@2,COG0787@1,COG0787@2 NA|NA|NA M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids MAG.T22.3_01998 1239962.C943_03445 1.8e-107 395.6 Bacteria Bacteria COG0810@1,COG0810@2 NA|NA|NA M energy transducer activity MAG.T22.3_01999 1239962.C943_03446 2.5e-93 348.2 Cytophagia Bacteria 2DD4I@1,32U0W@2,47R76@768503,4NTHG@976 NA|NA|NA MAG.T22.3_02000 1239962.C943_03447 6.1e-203 713.4 Cytophagia Bacteria 47KR8@768503,4NEN9@976,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T22.3_02001 1239962.C943_03466 3.4e-61 242.3 Cytophagia 4.6.1.13 ko:K01771 ko00562,map00562 R03332 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 47QV9@768503,4NQIN@976,COG0823@1,COG0823@2 NA|NA|NA U WD40-like Beta Propeller Repeat MAG.T22.3_02002 1189612.A33Q_2340 2e-95 355.5 Cytophagia ko:K07090 ko00000 Bacteria 47X4Q@768503,4NKE8@976,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE MAG.T22.3_02003 700598.Niako_4069 3.2e-70 272.3 Bacteroidetes Bacteria 4NZYI@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.3_02004 700598.Niako_4070 0.0 1246.5 Bacteria Bacteria COG0841@1,COG0841@2 NA|NA|NA V transmembrane transporter activity MAG.T22.3_02005 1288963.ADIS_3795 1.6e-148 532.7 Cytophagia Bacteria 47X87@768503,4P29H@976,COG1538@1,COG1538@2 NA|NA|NA MU Outer membrane efflux protein MAG.T22.3_02006 1288963.ADIS_2258 3.1e-97 361.7 Cytophagia Bacteria 47RSM@768503,4NJ72@976,COG2207@1,COG2207@2 NA|NA|NA K AraC-like ligand binding domain MAG.T22.3_02007 1239962.C943_03448 1.2e-163 582.4 Cytophagia fdh 1.1.1.316 ko:K17744 ko00053,ko01100,ko01110,map00053,map01100,map01110 M00114 R07675 RC00161 ko00000,ko00001,ko00002,ko01000 Bacteria 47P1M@768503,4NGIT@976,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family MAG.T22.3_02008 1239962.C943_03449 9.8e-178 629.4 Cytophagia yjmD_1 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 47M63@768503,4NHCK@976,COG1063@1,COG1063@2 NA|NA|NA E Alcohol dehydrogenase GroES-like domain MAG.T22.3_02009 1239962.C943_03450 1.1e-131 476.1 Cytophagia Bacteria 47N0E@768503,4NHBD@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T22.3_02010 1239962.C943_03451 6.7e-59 233.0 Cytophagia 5.1.3.32 ko:K03534 R10819 RC00563 ko00000,ko01000 Bacteria 47QS9@768503,4NRBV@976,COG3254@1,COG3254@2 NA|NA|NA S Pfam:DUF718 MAG.T22.3_02011 926562.Oweho_1416 2.8e-21 107.8 Cryomorphaceae Bacteria 1II0X@117743,2PC3I@246874,4P9T8@976,COG3668@1,COG3668@2 NA|NA|NA S ParE toxin of type II toxin-antitoxin system, parDE MAG.T22.3_02013 1239962.C943_03452 2.8e-218 764.2 Cytophagia Bacteria 47NS9@768503,4NEJM@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.3_02014 1239962.C943_03453 1e-159 569.3 Cytophagia 5.1.3.30,5.1.3.31 ko:K18910 R10817,R10818 RC03111,RC03283 ko00000,ko01000 Bacteria 47KII@768503,4NI7Y@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T22.3_02015 1239962.C943_03454 0.0 2335.1 Cytophagia ko:K09992 ko00000 Bacteria 47JTV@768503,4NFYI@976,COG1413@1,COG1413@2,COG2133@1,COG2133@2,COG3241@1,COG3241@2,COG3828@1,COG3828@2 NA|NA|NA CG PFAM Blue (type 1) copper domain MAG.T22.3_02016 1239962.C943_03455 1.2e-163 582.4 Cytophagia mltR Bacteria 47M1I@768503,4NGE5@976,COG2207@1,COG2207@2 NA|NA|NA K AraC-like ligand binding domain MAG.T22.3_02017 1189612.A33Q_2107 5.3e-156 557.4 Cytophagia ko:K07133 ko00000 Bacteria 47KTC@768503,4NE39@976,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) MAG.T22.3_02020 1239962.C943_03456 2.7e-143 514.6 Cytophagia Bacteria 47SN5@768503,4NSJ3@976,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon MAG.T22.3_02021 1239962.C943_03457 0.0 1676.8 Cytophagia mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 47JE2@768503,4NEGB@976,COG0249@1,COG0249@2 NA|NA|NA L that it carries out the mismatch recognition step. This protein has a weak ATPase activity MAG.T22.3_02022 1239962.C943_03458 2.8e-91 341.3 Cytophagia spoU 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 47PEY@768503,4NM8C@976,COG0566@1,COG0566@2 NA|NA|NA J PFAM SpoU rRNA Methylase family MAG.T22.3_02023 1123057.P872_05385 1.8e-14 85.5 Cytophagia Bacteria 2EP2H@1,33GPC@2,47T3B@768503,4NXTP@976 NA|NA|NA MAG.T22.3_02024 1239962.C943_03460 4.2e-53 213.8 Cytophagia csaA GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0017101,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20,6.1.1.6 ko:K01874,ko:K01890,ko:K04566,ko:K06878 ko00450,ko00970,map00450,map00970 M00359,M00360 R03658,R03659,R03660,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 47R4J@768503,4NQ9I@976,COG0073@1,COG0073@2 NA|NA|NA J TIGRFAM export-related chaperone CsaA MAG.T22.3_02025 1239962.C943_03461 3.9e-136 490.7 Cytophagia Bacteria 28HQQ@1,2Z7YB@2,47QT8@768503,4NJCY@976 NA|NA|NA MAG.T22.3_02026 1239962.C943_03462 4.5e-205 720.3 Cytophagia gfo 1.1.99.28 ko:K00118 ko00000,ko01000 Bacteria 47K0H@768503,4NE75@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.3_02027 1189612.A33Q_2596 1.4e-153 549.3 Bacteroidetes ko:K07133 ko00000 Bacteria 4NE39@976,COG1373@1,COG1373@2 NA|NA|NA S ATPase (AAA superfamily) MAG.T22.3_02028 1239962.C943_03463 0.0 1080.5 Cytophagia ko:K03929 ko00000,ko01000 CE10 Bacteria 47MY3@768503,4NF5N@976,COG2272@1,COG2272@2 NA|NA|NA I Belongs to the type-B carboxylesterase lipase family MAG.T22.3_02029 1239962.C943_03464 1.7e-128 465.3 Cytophagia 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 47N3I@768503,4NIYI@976,COG1051@1,COG1051@2 NA|NA|NA F NUDIX hydrolase MAG.T22.3_02030 1239962.C943_03465 1.3e-97 362.5 Cytophagia Bacteria 47PZ0@768503,4NMWH@976,COG2353@1,COG2353@2 NA|NA|NA S Belongs to the UPF0312 family MAG.T22.3_02031 1239962.C943_03467 0.0 1149.0 Cytophagia recJ ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 47MAC@768503,4NDW1@976,COG0608@1,COG0608@2 NA|NA|NA L single-stranded-DNA-specific exonuclease RecJ MAG.T22.3_02032 1239962.C943_03468 5.4e-130 470.3 Cytophagia lptB GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K01990,ko:K06861 ko02010,map02010 M00254,M00320 ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1,3.A.1 Bacteria 47KI2@768503,4NDUG@976,COG1137@1,COG1137@2 NA|NA|NA S ABC transporter MAG.T22.3_02033 1239962.C943_03469 5.5e-294 1016.1 Cytophagia Bacteria 47KAH@768503,4PKJY@976,COG0318@1,COG0318@2 NA|NA|NA IQ PFAM GH3 auxin-responsive promoter MAG.T22.3_02037 1239962.C943_03473 5.7e-129 466.8 Cytophagia mtgA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008955,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.129,3.4.16.4 ko:K03814,ko:K05365 ko00550,map00550 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 47MHF@768503,4NF90@976,COG0744@1,COG0744@2 NA|NA|NA M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors MAG.T22.3_02038 1239962.C943_03474 3.2e-147 527.7 Cytophagia Bacteria 47PH1@768503,4NMJ2@976,COG4122@1,COG4122@2 NA|NA|NA S O-methyltransferase MAG.T22.3_02039 1239962.C943_03475 0.0 1266.9 Cytophagia Bacteria 47NCY@768503,4NEKT@976,COG1305@1,COG1305@2 NA|NA|NA E Domain of Unknown Function with PDB structure (DUF3857) MAG.T22.3_02040 1239962.C943_03476 0.0 1204.5 Bacteria Bacteria COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase-like superfamily MAG.T22.3_02041 1239962.C943_03477 1.2e-82 312.4 Cytophagia nodN 4.2.1.55 ko:K17865 ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200 M00373 R03027 RC00831 ko00000,ko00001,ko00002,ko01000 Bacteria 47PBK@768503,4NNHH@976,COG2030@1,COG2030@2 NA|NA|NA I Acyl dehydratase MAG.T22.3_02042 1239962.C943_03478 9.3e-133 479.6 Cytophagia ydfG 1.1.1.276 ko:K05886 ko00000,ko01000 Bacteria 47MMM@768503,4NE1R@976,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T22.3_02043 1239962.C943_03479 2e-129 468.4 Cytophagia ddpX GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009046,GO:0009605,GO:0009991,GO:0016787,GO:0019538,GO:0031667,GO:0042594,GO:0043170,GO:0044238,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.13.22 ko:K07282,ko:K08641 ko01502,ko02020,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Bacteria 47R25@768503,4NE2K@976,COG2173@1,COG2173@2 NA|NA|NA M Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide MAG.T22.3_02044 1239962.C943_03480 1.1e-141 509.2 Cytophagia ko:K09992 ko00000 Bacteria 47PB3@768503,4NJ6A@976,COG3828@1,COG3828@2 NA|NA|NA G Trehalose utilisation MAG.T22.3_02045 1239962.C943_03481 2.6e-135 488.0 Cytophagia Bacteria 28PB4@1,2ZC42@2,47QQM@768503,4NJ4V@976 NA|NA|NA MAG.T22.3_02046 1239962.C943_03482 5.4e-77 293.5 Cytophagia Bacteria 2DNUQ@1,32Z94@2,47QAG@768503,4NVH0@976 NA|NA|NA S Domain of unknown function (DUF4281) MAG.T22.3_02047 1239962.C943_03483 3.9e-226 790.4 Cytophagia sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 47NAK@768503,4NEV7@976,COG0144@1,COG0144@2 NA|NA|NA J TIGRFAM ribosomal RNA small subunit methyltransferase RsmB MAG.T22.3_02048 1239962.C943_03484 1.9e-195 688.3 Cytophagia prfA GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02835 ko00000,ko03012 Bacteria 47M9W@768503,4NF72@976,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA MAG.T22.3_02049 1239962.C943_03485 2e-103 381.7 Cytophagia Bacteria 47RAN@768503,4NQB5@976,COG1670@1,COG1670@2 NA|NA|NA J PFAM Acetyltransferase (GNAT) family MAG.T22.3_02050 1239962.C943_03486 3.3e-222 777.3 Cytophagia Bacteria 47Y2C@768503,4NMUN@976,COG0729@1,COG0729@2 NA|NA|NA M Surface antigen MAG.T22.3_02051 1239962.C943_03487 6.1e-216 756.5 Cytophagia ko:K07133 ko00000 Bacteria 47JKG@768503,4NHSW@976,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) MAG.T22.3_02052 1239962.C943_03488 0.0 1583.2 Cytophagia Bacteria 47KCK@768503,4NE13@976,COG0308@1,COG0308@2 NA|NA|NA E Aminopeptidase N MAG.T22.3_02053 1239962.C943_00699 2.1e-97 361.7 Cytophagia Bacteria 47MSF@768503,4NMRP@976,COG2370@1,COG2370@2 NA|NA|NA O HupE / UreJ protein MAG.T22.3_02054 1239962.C943_00700 7.8e-85 319.7 Cytophagia Bacteria 2AE6H@1,3140B@2,47RV6@768503,4NSDV@976 NA|NA|NA MAG.T22.3_02055 388467.A19Y_2601 4.5e-25 120.9 Oscillatoriales ko:K07063 ko00000 Bacteria 1G7ZZ@1117,1HCQ7@1150,COG1569@1,COG1569@2 NA|NA|NA S PIN domain MAG.T22.3_02058 485917.Phep_1092 1.4e-12 79.0 Sphingobacteriia Bacteria 1IZVP@117747,4PA82@976,COG3668@1,COG3668@2 NA|NA|NA S Plasmid stabilization system MAG.T22.3_02059 1239962.C943_00703 2.9e-98 364.4 Cytophagia nbaC 1.13.11.6 ko:K00452 ko00380,ko01100,map00380,map01100 M00038 R02665 RC00387 ko00000,ko00001,ko00002,ko01000 Bacteria 47PIW@768503,4NFU2@976,COG0662@1,COG0662@2 NA|NA|NA G Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate MAG.T22.3_02060 1239962.C943_00704 2e-188 664.8 Cytophagia CP_0490 3.4.13.19 ko:K01273 ko00000,ko00537,ko01000,ko01002,ko04147 Bacteria 47K2D@768503,4NDX6@976,COG2355@1,COG2355@2 NA|NA|NA E Membrane dipeptidase (Peptidase family M19) MAG.T22.3_02061 1239962.C943_00705 1.8e-212 745.0 Cytophagia Bacteria 47JHK@768503,4NICB@976,COG4775@1,COG4775@2 NA|NA|NA M Surface antigen MAG.T22.3_02062 1239962.C943_00706 0.0 1199.5 Cytophagia Bacteria 47MEA@768503,4NH4I@976,COG2866@1,COG2866@2 NA|NA|NA E Zn_pept MAG.T22.3_02063 1239962.C943_00707 8.7e-306 1055.4 Cytophagia Bacteria 47MR4@768503,4NHBS@976,COG2866@1,COG2866@2 NA|NA|NA E Zinc carboxypeptidase MAG.T22.3_02064 1239962.C943_00708 2.2e-148 531.6 Cytophagia ko:K14061 ko00000 Bacteria 47T99@768503,4NGG8@976,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein family MAG.T22.3_02065 1239962.C943_00709 1.9e-207 728.4 Cytophagia Bacteria 47NZK@768503,4NFPE@976,COG0475@1,COG0475@2 NA|NA|NA P Sodium/hydrogen exchanger family MAG.T22.3_02066 1239962.C943_00710 7.1e-99 366.7 Cytophagia ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 47P7G@768503,4NN8S@976,COG3127@1,COG3127@2 NA|NA|NA Q membrane MAG.T22.3_02067 1239962.C943_00711 1.8e-44 184.9 Cytophagia MA20_23570 ko:K03892 ko00000,ko03000 Bacteria 47R9V@768503,4NSAV@976,COG0640@1,COG0640@2 NA|NA|NA K Winged helix DNA-binding domain MAG.T22.3_02068 1239962.C943_00713 6.7e-203 713.4 Bacteroidetes creD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06143 ko00000 Bacteria 4NGKY@976,COG4452@1,COG4452@2 NA|NA|NA V Inner membrane protein, CreD MAG.T22.3_02069 1239962.C943_00715 8.2e-168 596.3 Cytophagia rsgA 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 Bacteria 47JC5@768503,4NE5H@976,COG1162@1,COG1162@2 NA|NA|NA S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit MAG.T22.3_02070 1239962.C943_00716 4.6e-197 693.7 Cytophagia cyoE ko:K06921 ko00000 Bacteria 47VKT@768503,4NGM3@976,COG1672@1,COG1672@2 NA|NA|NA S ATPase (AAA superfamily) MAG.T22.3_02071 1239962.C943_00717 1.5e-231 808.5 Cytophagia Bacteria 47N82@768503,4PJFT@976,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system MAG.T22.3_02072 1239962.C943_00718 2.5e-205 721.5 Cytophagia gltP Bacteria 47KI1@768503,4NDUU@976,COG1301@1,COG1301@2 NA|NA|NA C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family MAG.T22.3_02073 1239962.C943_00719 1.9e-195 688.3 Cytophagia aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 iIT341.HP0663,iJN678.aroC Bacteria 47KB2@768503,4NDXJ@976,COG0082@1,COG0082@2 NA|NA|NA E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system MAG.T22.3_02074 1239962.C943_00720 2.4e-270 937.6 Bacteria Bacteria COG4783@1,COG4783@2 NA|NA|NA L chaperone-mediated protein folding MAG.T22.3_02075 1239962.C943_00721 7.6e-28 129.0 Cytophagia Bacteria 2A7GX@1,30WEH@2,47S3Y@768503,4P9UT@976 NA|NA|NA MAG.T22.3_02076 1239962.C943_00722 2.1e-229 801.2 Cytophagia Bacteria 47M7W@768503,4NFWE@976,COG0454@1,COG0456@2 NA|NA|NA K Psort location Cytoplasmic, score 8.96 MAG.T22.3_02077 1239962.C943_00725 4e-178 630.6 Cytophagia queG GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 ko00000,ko01000,ko03016 Bacteria 47JAQ@768503,4NFCJ@976,COG1600@1,COG1600@2 NA|NA|NA C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) MAG.T22.3_02078 1239962.C943_00726 9.1e-193 679.5 Cytophagia ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 47M82@768503,4NEB9@976,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing MAG.T22.3_02079 1239962.C943_00727 4.7e-191 673.7 Cytophagia apbE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564 1.8.1.2,2.7.1.180 ko:K00380,ko:K03734 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 Bacteria 47N34@768503,4NGEK@976,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein MAG.T22.3_02080 1239962.C943_00728 5.3e-123 447.2 Cytophagia zupT ko:K07238,ko:K11021,ko:K16267 ko00000,ko02000,ko02042 2.A.5.4.11,2.A.5.5 Bacteria 47Q1F@768503,4NG1R@976,COG0428@1,COG0428@2 NA|NA|NA P ZIP Zinc transporter MAG.T22.3_02083 762903.Pedsa_0334 9.8e-31 139.4 Sphingobacteriia ko:K06218 ko00000,ko02048 Bacteria 1IU0G@117747,4NW0W@976,COG2026@1,COG2026@2 NA|NA|NA DJ Psort location Cytoplasmic, score 8.96 MAG.T22.3_02084 1150600.ADIARSV_1290 7e-19 99.4 Sphingobacteriia Bacteria 1IZBG@117747,2C6XB@1,33J5D@2,4NXZE@976 NA|NA|NA MAG.T22.3_02085 1239962.C943_00729 3.1e-40 170.6 Cytophagia Bacteria 47RH4@768503,4NSV7@976,COG4327@1,COG4327@2 NA|NA|NA S Domain of unknown function (DUF4212) MAG.T22.3_02086 1239962.C943_00730 2.7e-294 1017.3 Cytophagia actP ko:K14393 ko00000,ko02000 2.A.21.7 Bacteria 47JSK@768503,4NHPT@976,COG4147@1,COG4147@2 NA|NA|NA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family MAG.T22.3_02087 1239962.C943_00731 0.0 1290.8 Cytophagia acsA GO:0003674,GO:0003824,GO:0003987,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006084,GO:0006085,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006473,GO:0006476,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016054,GO:0016405,GO:0016787,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018193,GO:0018205,GO:0018394,GO:0019213,GO:0019427,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033558,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034421,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045733,GO:0046390,GO:0046395,GO:0046483,GO:0050218,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072329,GO:0072521,GO:0072522,GO:0090407,GO:0098732,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 iE2348C_1286.E2348C_4392,iYL1228.KPN_04478 Bacteria 47JMW@768503,4NEAD@976,COG0365@1,COG0365@2 NA|NA|NA I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA MAG.T22.3_02088 1123278.KB893548_gene4728 9.4e-17 92.4 Cytophagia Bacteria 47X60@768503,4NZ3D@976,COG2442@1,COG2442@2 NA|NA|NA S Protein of unknown function (DUF433) MAG.T22.3_02089 237368.SCABRO_00945 1.5e-16 92.4 Planctomycetes Bacteria 2J4DQ@203682,COG4634@1,COG4634@2 NA|NA|NA MAG.T22.3_02090 1239962.C943_00733 0.0 1203.7 Cytophagia ko:K07182 ko00000 Bacteria 47NMX@768503,4NDZ8@976,COG2905@1,COG2905@2 NA|NA|NA T signal-transduction protein containing cAMP-binding and CBS domains MAG.T22.3_02091 1239962.C943_00734 9.4e-113 412.9 Cytophagia polC1 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 47PI2@768503,4NMUI@976,COG0847@1,COG0847@2 NA|NA|NA L EXOIII MAG.T22.3_02092 1239962.C943_00735 0.0 1431.0 Cytophagia ko:K02014 ko00000,ko02000 1.B.14 Bacteria 47M2B@768503,4NE9I@976,COG4772@1,COG4772@2 NA|NA|NA P TonB-dependent receptor MAG.T22.3_02093 1239962.C943_00737 6e-76 290.0 Cytophagia rpiB 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 47PQK@768503,4NNSU@976,COG0698@1,COG0698@2 NA|NA|NA G Ribose 5-phosphate isomerase MAG.T22.3_02094 1239962.C943_00738 1e-135 489.6 Cytophagia tatC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 ko:K03118 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 47KG0@768503,4NEKM@976,COG0805@1,COG0805@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes MAG.T22.3_02095 1239962.C943_00739 5e-240 836.6 Cytophagia glyA GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 iG2583_1286.G2583_3081,iIT341.HP0183 Bacteria 47JWG@768503,4NE30@976,COG0112@1,COG0112@2 NA|NA|NA E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism MAG.T22.3_02096 1239962.C943_00740 0.0 1437.6 Cytophagia ko:K02014,ko:K16087 ko00000,ko02000 1.B.14,1.B.14.2 Bacteria 47JHA@768503,4NFQD@976,COG1629@1,COG4771@2 NA|NA|NA P TonB-dependent receptor MAG.T22.3_02097 866536.Belba_1188 3.3e-27 127.9 Cytophagia Bacteria 2EE92@1,3383G@2,47SKH@768503,4NUZJ@976 NA|NA|NA MAG.T22.3_02098 1121859.KB890738_gene3502 1.4e-25 122.5 Cytophagia Bacteria 2CEJ3@1,33XW6@2,47UY5@768503,4P39I@976 NA|NA|NA MAG.T22.3_02099 1239962.C943_00744 2.7e-147 528.1 Cytophagia ko:K07088 ko00000 Bacteria 47Q60@768503,4NIQF@976,COG0679@1,COG0679@2 NA|NA|NA S PFAM Membrane transport protein MAG.T22.3_02100 1239962.C943_00745 0.0 1607.4 Cytophagia Bacteria 47K94@768503,4NG2S@976,COG1629@1,COG1629@2,COG2373@1,COG2373@2 NA|NA|NA P TonB-dependent Receptor Plug Domain MAG.T22.3_02101 1239962.C943_00746 3.9e-149 534.6 Cytophagia Bacteria 47QPG@768503,4NQGN@976,COG1629@1,COG1629@2 NA|NA|NA P CarboxypepD_reg-like domain MAG.T22.3_02102 1239962.C943_00747 0.0 1344.3 Cytophagia fucA 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria 47JNA@768503,4NEDX@976,COG3669@1,COG3669@2 NA|NA|NA G Coagulation factor 5 8 type domain protein MAG.T22.3_02104 1239962.C943_00751 0.0 1956.8 Cytophagia Bacteria 47JQ1@768503,4NHCZ@976,COG0457@1,COG0457@2,COG4995@1,COG4995@2 NA|NA|NA S CHAT domain MAG.T22.3_02105 1239962.C943_00753 1.9e-204 718.4 Cytophagia 3.5.1.81 ko:K06015 R02192 RC00064,RC00328 ko00000,ko01000 Bacteria 47PNH@768503,4NF42@976,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T22.3_02106 1239962.C943_00758 1.7e-99 368.6 Cytophagia ko:K03088,ko:K03091 ko00000,ko03021 Bacteria 47PTU@768503,4NM40@976,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family MAG.T22.3_02107 1239962.C943_00759 6.9e-133 479.9 Cytophagia Bacteria 47XT7@768503,4NNXW@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.3_02108 866536.Belba_2728 4.4e-48 197.6 Cytophagia Bacteria 2E6GM@1,3313V@2,47W8D@768503,4NT39@976 NA|NA|NA MAG.T22.3_02110 1358423.N180_00965 8.8e-12 77.8 Sphingobacteriia Bacteria 1IXYS@117747,2ED4Y@1,3371P@2,4NX0S@976 NA|NA|NA MAG.T22.3_02111 1358423.N180_00965 3.9e-17 94.7 Sphingobacteriia Bacteria 1IXYS@117747,2ED4Y@1,3371P@2,4NX0S@976 NA|NA|NA MAG.T22.3_02112 1239962.C943_01449 6.1e-168 597.0 Cytophagia Bacteria 47Q5X@768503,4NHJS@976,COG1503@1,COG1503@2 NA|NA|NA J translation release factor activity MAG.T22.3_02113 1239962.C943_01447 2.6e-193 681.4 Bacteroidetes Bacteria 28H6R@1,2Z7J3@2,4P1VZ@976 NA|NA|NA S Psort location CytoplasmicMembrane, score MAG.T22.3_02114 1239962.C943_02243 1.6e-126 459.5 Cytophagia Bacteria 47QHX@768503,4NHNW@976,COG4775@1,COG4775@2 NA|NA|NA M Surface antigen MAG.T22.3_02115 388467.A19Y_3668 0.0 1471.8 Oscillatoriales Bacteria 1G119@1117,1H81R@1150,COG0286@1,COG0286@2 NA|NA|NA V N-6 DNA Methylase MAG.T22.3_02116 1239962.C943_02241 1.3e-69 270.4 Cytophagia Bacteria 47XEP@768503,4NWRQ@976,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein MAG.T22.3_02117 1120966.AUBU01000013_gene437 7.4e-60 236.9 Bacteroidetes Bacteria 2BVY1@1,32QYH@2,4NR2M@976 NA|NA|NA MAG.T22.3_02118 1120966.AUBU01000013_gene438 1e-126 459.9 Cytophagia Bacteria 47MEW@768503,4NIF2@976,COG0560@1,COG0560@2 NA|NA|NA E haloacid dehalogenase-like hydrolase MAG.T22.3_02119 1239962.C943_00761 4.5e-291 1006.5 Cytophagia 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 47JCN@768503,4NFRB@976,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase MAG.T22.3_02120 1239962.C943_00762 2.9e-243 847.4 Cytophagia cefD Bacteria 47KCX@768503,4NF4G@976,COG0520@1,COG0520@2 NA|NA|NA E PFAM aminotransferase class V MAG.T22.3_02121 1239962.C943_00763 1.9e-162 578.6 Cytophagia Bacteria 28ICX@1,2Z9XD@2,47XT4@768503,4NIE3@976 NA|NA|NA MAG.T22.3_02122 1239962.C943_00764 2.2e-119 435.3 Cytophagia ko:K13582 ko04112,map04112 ko00000,ko00001 Bacteria 47R2R@768503,4NP00@976,COG3206@1,COG3206@2 NA|NA|NA M Domain of unknown function (DUF4349) MAG.T22.3_02123 1239962.C943_00765 3e-59 234.6 Cytophagia Bacteria 2BU29@1,32PAZ@2,47T58@768503,4PABG@976 NA|NA|NA MAG.T22.3_02124 1408473.JHXO01000002_gene3914 1.3e-60 240.4 Bacteroidia Bacteria 2FS0W@200643,4NP5N@976,COG0457@1,COG0457@2 NA|NA|NA S TPR repeat MAG.T22.3_02125 391598.FBBAL38_12350 1.6e-22 113.2 Flavobacteriia Bacteria 1I532@117743,2AZX3@1,31S6U@2,4NQEW@976 NA|NA|NA S Domain of unknown function (DUF4328) MAG.T22.3_02126 1239962.C943_00766 9.4e-196 689.5 Cytophagia ko:K03863 ko00627,ko01120,map00627,map01120 R05274 RC00392,RC01533 ko00000,ko00001 Bacteria 47MGY@768503,4NEXX@976,COG3182@1,COG3182@2 NA|NA|NA S PepSY-associated TM region MAG.T22.3_02127 1189612.A33Q_2279 7e-33 146.4 Bacteroidetes ko:K19092 ko00000,ko02048 Bacteria 4NSJ0@976,COG3668@1,COG3668@2 NA|NA|NA S ParE toxin of type II toxin-antitoxin system, parDE MAG.T22.3_02128 1121012.AUKX01000064_gene1082 1.6e-25 121.7 Flavobacteriia ko:K07746 ko00000,ko02048 Bacteria 1I3XS@117743,4NTDN@976,COG3609@1,COG3609@2 NA|NA|NA K addiction module antidote protein, CC2985 family MAG.T22.3_02129 1239962.C943_00767 5.7e-191 673.3 Cytophagia lptA 3.5.1.28 ko:K01447,ko:K01448,ko:K09774 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko02000,ko03036 1.B.42.1 Bacteria 47T11@768503,4NGPT@976,COG3103@1,COG4991@2 NA|NA|NA T Bacterial SH3 domain homologues MAG.T22.3_02134 1239962.C943_02133 3.6e-154 550.8 Cytophagia Bacteria 47KY4@768503,4NIPS@976,COG1305@1,COG1305@2 NA|NA|NA E transglutaminase domain protein MAG.T22.3_02135 1239962.C943_02132 3e-136 491.1 Cytophagia MA20_32445 ko:K07395 ko00000 Bacteria 47MX7@768503,4NGR7@976,COG3484@1,COG3484@2 NA|NA|NA O Proteasome subunit MAG.T22.3_02136 1239962.C943_02131 1.2e-180 639.0 Cytophagia Bacteria 47JTD@768503,4NHIB@976,COG2307@1,COG2307@2 NA|NA|NA S A predicted alpha-helical domain with a conserved ER motif. MAG.T22.3_02137 1239962.C943_02130 8e-279 965.7 Cytophagia gcs2 Bacteria 47JU4@768503,4NFMN@976,COG2308@1,COG2308@2 NA|NA|NA S Circularly permuted ATP-grasp type 2 MAG.T22.3_02138 1239962.C943_02127 0.0 1381.7 Cytophagia metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 ko:K01874,ko:K01890,ko:K06878 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R03660,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iEC042_1314.EC042_2346,iECUMN_1333.ECUMN_2446 Bacteria 47JB3@768503,4NECB@976,COG0073@1,COG0073@2,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation MAG.T22.3_02139 1239962.C943_02126 4.6e-93 347.4 Cytophagia ko:K09017 ko00000,ko03000 Bacteria 47K37@768503,4NHIJ@976,COG1309@1,COG1309@2 NA|NA|NA K tetR family MAG.T22.3_02140 1239962.C943_02124 0.0 1513.8 Cytophagia ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972,ko:K10754 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 M00289,M00295 R00382 RC00005 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 47KR4@768503,4NE2X@976,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA MAG.T22.3_02141 1189612.A33Q_2898 1.3e-39 169.5 Cytophagia Bacteria 2DVEH@1,33VI7@2,47UNI@768503,4P2TF@976 NA|NA|NA MAG.T22.3_02142 1239962.C943_02122 2.1e-149 535.0 Cytophagia dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 47MC7@768503,4NFP9@976,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) MAG.T22.3_02143 1121904.ARBP01000009_gene4366 9.2e-48 196.4 Cytophagia Bacteria 2CKSR@1,30RNP@2,47VAI@768503,4PB67@976 NA|NA|NA MAG.T22.3_02144 1239962.C943_02120 2e-132 478.4 Cytophagia ydcC Bacteria 47RIH@768503,4NHV3@976,COG2834@1,COG2834@2 NA|NA|NA M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) MAG.T22.3_02145 1239962.C943_02119 0.0 2024.2 Cytophagia Bacteria 47P32@768503,4NESU@976,COG4447@1,COG4447@2 NA|NA|NA S Sortilin, neurotensin receptor 3, MAG.T22.3_02146 866536.Belba_1427 6e-156 557.4 Cytophagia ko:K06921 ko00000 Bacteria 47UIW@768503,4NJ2E@976,COG1672@1,COG1672@2 NA|NA|NA S Pfam:Arch_ATPase MAG.T22.3_02148 1239962.C943_02117 1.5e-308 1064.7 Cytophagia fhs GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.5,3.5.4.9,6.3.4.3 ko:K00288,ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00141,M00377 R00943,R01220,R01655 RC00026,RC00111,RC00202,RC00578 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47T90@768503,4NG3E@976,COG2759@1,COG2759@2 NA|NA|NA F Formate--tetrahydrofolate ligase MAG.T22.3_02149 1239962.C943_02115 2.1e-119 435.3 Cytophagia ko:K03668,ko:K09914 ko00000 Bacteria 47SMJ@768503,4NSEQ@976,COG3015@1,COG3015@2,COG3187@1,COG3187@2 NA|NA|NA MP NlpE N-terminal domain MAG.T22.3_02150 1239962.C943_02114 6e-137 493.4 Cytophagia Bacteria 2E0BQ@1,32VYW@2,47RBI@768503,4NUK5@976 NA|NA|NA MAG.T22.3_02151 1239962.C943_02113 0.0 1847.4 Cytophagia Bacteria 47N2Q@768503,4NDVD@976,COG1506@1,COG1506@2 NA|NA|NA E Prolyl oligopeptidase family MAG.T22.3_02152 1239962.C943_02112 0.0 1285.8 Cytophagia Bacteria 47K8F@768503,4NIJ0@976,COG2866@1,COG2866@2 NA|NA|NA E Zn_pept MAG.T22.3_02153 1239962.C943_02110 5.7e-86 323.6 Cytophagia Bacteria 28XP4@1,2ZJK0@2,47RPT@768503,4NTVD@976 NA|NA|NA MAG.T22.3_02154 1239962.C943_02109 5.6e-80 303.5 Cytophagia asnC ko:K03718 ko00000,ko03000 Bacteria 47PXD@768503,4NHG9@976,COG1522@1,COG1522@2 NA|NA|NA K helix_turn_helix ASNC type MAG.T22.3_02155 1239962.C943_02108 1.2e-279 968.4 Cytophagia sufB GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 ko:K07033,ko:K09014 ko00000 iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078 Bacteria 47JZJ@768503,4NFXH@976,COG0719@1,COG0719@2 NA|NA|NA O TIGRFAM FeS assembly protein SufB MAG.T22.3_02156 1239962.C943_02107 8.9e-136 489.6 Cytophagia sufC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 ko:K09013 ko00000,ko02000 iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710 Bacteria 47N88@768503,4NEMY@976,COG0396@1,COG0396@2 NA|NA|NA O TIGRFAM FeS assembly ATPase SufC MAG.T22.3_02157 1239962.C943_02106 8e-222 776.2 Cytophagia sufD GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 ko:K07033,ko:K09015 ko00000 iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144 Bacteria 47K0R@768503,4NFPG@976,COG0719@1,COG0719@2 NA|NA|NA O TIGRFAM FeS assembly protein SufD MAG.T22.3_02158 1239962.C943_02105 5e-221 773.5 Cytophagia sufS 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 Bacteria 47JNS@768503,4NDUB@976,COG0520@1,COG0520@2 NA|NA|NA E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine MAG.T22.3_02159 1239962.C943_02104 1e-72 279.3 Cytophagia sufE ko:K02426 ko00000 Bacteria 47Q7A@768503,4NM9N@976,COG2166@1,COG2166@2 NA|NA|NA S SufE protein probably involved in Fe-S center assembly MAG.T22.3_02160 1239962.C943_02103 5.1e-51 206.8 Cytophagia paaD ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 47QBC@768503,4NSA9@976,COG2151@1,COG2151@2 NA|NA|NA S FeS assembly SUF system protein MAG.T22.3_02161 1239962.C943_02102 8.3e-75 286.2 Cytophagia yqiW Bacteria 28NYH@1,2ZBVN@2,47QD1@768503,4NMB2@976 NA|NA|NA S Belongs to the UPF0403 family MAG.T22.3_02162 1239962.C943_02101 1.3e-248 865.1 Cytophagia gltA 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 47JIN@768503,4NFXK@976,COG0372@1,COG0372@2 NA|NA|NA C Belongs to the citrate synthase family MAG.T22.3_02163 1239962.C943_02099 1.8e-38 164.9 Cytophagia dbi Bacteria 47RZ1@768503,4NVK0@976,COG4281@1,COG4281@2 NA|NA|NA I Acyl CoA binding protein MAG.T22.3_02164 1239962.C943_02098 1.8e-304 1051.2 Cytophagia deaD GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019439,GO:0022607,GO:0022613,GO:0022618,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032268,GO:0032270,GO:0032574,GO:0032575,GO:0033554,GO:0033592,GO:0034057,GO:0034248,GO:0034250,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043487,GO:0043488,GO:0043489,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045934,GO:0046483,GO:0046700,GO:0048255,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070035,GO:0070417,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1903311,GO:1903312,GO:2000112 3.6.4.13 ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 47KSE@768503,4NEJV@976,COG0513@1,COG0513@2 NA|NA|NA L Belongs to the DEAD box helicase family MAG.T22.3_02165 1239962.C943_02097 1.5e-143 515.4 Cytophagia 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 47KCT@768503,4NF20@976,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family MAG.T22.3_02166 1239962.C943_02096 1.2e-170 605.9 Cytophagia Bacteria 28MAS@1,318XW@2,47V0P@768503,4PPYP@976 NA|NA|NA S Protein of unknown function, DUF481 MAG.T22.3_02167 1239962.C943_02095 1.9e-75 288.9 Cytophagia Bacteria 2ATWF@1,31JFP@2,47X6Y@768503,4NQ9K@976 NA|NA|NA MAG.T22.3_02168 1239962.C943_02094 1.8e-159 568.5 Cytophagia Bacteria 47P1R@768503,4NJS5@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T22.3_02170 1239962.C943_02092 0.0 1630.2 Cytophagia ko:K09822 ko00000 Bacteria 47MDY@768503,4NECE@976,COG3002@1,COG3002@2 NA|NA|NA S Belongs to the UPF0753 family MAG.T22.3_02171 1239962.C943_02091 0.0 1208.7 Cytophagia nuoL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00341,ko:K12137 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 Bacteria 47NRZ@768503,4NEBM@976,COG1009@1,COG1009@2 NA|NA|NA CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus MAG.T22.3_02172 1239962.C943_02090 3.2e-292 1010.4 Cytophagia Bacteria 47KTW@768503,4NE9G@976,COG0659@1,COG0659@2 NA|NA|NA P Sulfate permease family MAG.T22.3_02174 1239962.C943_02088 3.9e-72 277.3 Cytophagia Bacteria 47QEP@768503,4NQ4A@976,COG3832@1,COG3832@2 NA|NA|NA S Activator of Hsp90 ATPase homolog 1-like protein MAG.T22.3_02175 1239962.C943_02087 3.5e-225 787.3 Cytophagia Bacteria 47PVI@768503,4NE70@976,COG3832@1,COG3832@2,COG3865@1,COG3865@2 NA|NA|NA S 3-demethylubiquinone-9 3-methyltransferase MAG.T22.3_02176 1239962.C943_02086 1.8e-284 984.6 Cytophagia Bacteria 47JSS@768503,4NEA7@976,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain MAG.T22.3_02178 1305737.JAFX01000001_gene3415 6.1e-48 196.8 Cytophagia Bacteria 47W3N@768503,4NVQT@976,COG1598@1,COG1598@2 NA|NA|NA S PFAM Uncharacterised protein family UPF0150 MAG.T22.3_02179 1239962.C943_02084 9.5e-63 246.1 Cytophagia Bacteria 2DX1S@1,34307@2,47V8Z@768503,4P4KQ@976 NA|NA|NA MAG.T22.3_02180 1239962.C943_02083 1e-116 426.0 Cytophagia gpm 5.4.2.11,5.4.2.12 ko:K01834,ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 47JSV@768503,4NFX5@976,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase family MAG.T22.3_02181 1239962.C943_02082 4.1e-74 283.9 Cytophagia menI GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0034641,GO:0042180,GO:0042181,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0061522,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 3.1.2.28 ko:K19222 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07262 RC00004,RC00174 ko00000,ko00001,ko00002,ko01000 Bacteria 47QEZ@768503,4NNYG@976,COG2050@1,COG2050@2 NA|NA|NA Q PFAM thioesterase superfamily MAG.T22.3_02182 1239962.C943_02081 3.5e-227 793.9 Cytophagia menF GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008909,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009233,GO:0009234,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042180,GO:0042181,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046872,GO:0050486,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901661,GO:1901663,GO:1902494 5.4.4.2 ko:K02361,ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 iECABU_c1320.ECABU_c26010,iECIAI39_1322.ECIAI39_2413,iSF_1195.SF2344,iS_1188.S2478,ic_1306.c2809 Bacteria 47K5Z@768503,4NF6U@976,COG1169@1,COG1169@2 NA|NA|NA HQ PFAM chorismate binding enzyme MAG.T22.3_02183 1239962.C943_02080 8.2e-307 1058.9 Cytophagia menD 2.2.1.9 ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08165 RC02186 ko00000,ko00001,ko00002,ko01000 Bacteria 47JS5@768503,4NETZ@976,COG1165@1,COG1165@2 NA|NA|NA H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) MAG.T22.3_02184 1239962.C943_02079 7.4e-153 546.6 Cytophagia Bacteria 47PQQ@768503,4NPYD@976,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins MAG.T22.3_02185 504472.Slin_2341 6.8e-32 143.7 Bacteroidetes Bacteria 4NSCB@976,COG5642@1,COG5642@2 NA|NA|NA S Protein of unknown function (DUF2384) MAG.T22.3_02186 1218108.KB908291_gene713 5.1e-38 164.1 Flavobacteriia Bacteria 1I5NZ@117743,4NR08@976,COG5654@1,COG5654@2 NA|NA|NA S RES MAG.T22.3_02187 1305737.JAFX01000001_gene3334 9.5e-09 68.2 Cytophagia Bacteria 47W3X@768503,4PAMX@976,COG3391@1,COG3391@2 NA|NA|NA S Domain of unknown function (DUF4934) MAG.T22.3_02188 1239962.C943_02078 4.6e-64 250.4 Cytophagia vapC Bacteria 47WEI@768503,4P7XI@976,COG1487@1,COG1487@2 NA|NA|NA S PIN domain MAG.T22.3_02189 1239962.C943_02077 9.1e-27 125.6 Cytophagia Bacteria 2DYQ7@1,34ANJ@2,47W1C@768503,4P601@976 NA|NA|NA MAG.T22.3_02190 1239962.C943_02076 2.4e-156 558.1 Cytophagia alsR Bacteria 47NDC@768503,4NGAB@976,COG0583@1,COG0583@2 NA|NA|NA K Bacterial regulatory helix-turn-helix protein, lysR family MAG.T22.3_02191 1239962.C943_02075 2.8e-82 311.2 Bacteroidetes glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iAF987.Gmet_1487 Bacteria 4P1TS@976,COG0449@1,COG0449@2 NA|NA|NA M ORF6N domain MAG.T22.3_02192 1239962.C943_02074 9.7e-294 1015.4 Cytophagia hutH 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 Bacteria 47MP5@768503,4NE0D@976,COG2986@1,COG2986@2 NA|NA|NA E Histidine ammonia-lyase MAG.T22.3_02194 1239962.C943_02073 7.8e-222 776.2 Cytophagia hutI GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 iYO844.BSU39370 Bacteria 47K5F@768503,4NE6C@976,COG1228@1,COG1228@2 NA|NA|NA Q PFAM Amidohydrolase family MAG.T22.3_02195 1239962.C943_02070 0.0 1302.3 Cytophagia hutU GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_0688 Bacteria 47K5S@768503,4NF2P@976,COG2987@1,COG2987@2 NA|NA|NA E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate MAG.T22.3_02196 1239962.C943_02069 1.2e-123 449.1 Cytophagia Bacteria 47WKB@768503,4NPV9@976,COG3637@1,COG3637@2 NA|NA|NA M Outer membrane protein beta-barrel domain MAG.T22.3_02198 485917.Phep_2705 7.7e-25 120.2 Bacteroidetes ko:K07063 ko00000 Bacteria 4NX0E@976,COG1569@1,COG1569@2 NA|NA|NA S PIN domain MAG.T22.3_02200 1239962.C943_02851 1.8e-63 248.4 Bacteroidetes nfuA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010467,GO:0015976,GO:0016043,GO:0016226,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 ko:K07400,ko:K13628,ko:K15724 ko00000,ko03016 Bacteria 4NS6K@976,COG0316@1,COG0316@2 NA|NA|NA S Belongs to the HesB IscA family MAG.T22.3_02201 1239962.C943_02852 3.6e-88 330.9 Cytophagia Bacteria 28NWP@1,2ZBUH@2,47M02@768503,4NNPT@976 NA|NA|NA MAG.T22.3_02202 1239962.C943_02853 1.1e-63 249.2 Cytophagia XK27_09985 Bacteria 47QGK@768503,4NVFR@976,COG3339@1,COG3339@2 NA|NA|NA S Protein of unknown function (DUF1232) MAG.T22.3_02203 1239962.C943_02854 1.5e-129 468.8 Cytophagia Bacteria 47PTQ@768503,4NG89@976,COG0702@1,COG0702@2 NA|NA|NA GM epimerase MAG.T22.3_02204 1239962.C943_02855 6.8e-75 286.6 Cytophagia dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K07560 ko00000,ko01000,ko03016 Bacteria 47P8B@768503,4NNFF@976,COG1490@1,COG1490@2 NA|NA|NA J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality MAG.T22.3_02205 1239962.C943_02856 1.4e-273 948.3 Cytophagia modF GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21,3.6.3.34 ko:K02013,ko:K02028,ko:K05776 ko02010,map02010 M00189,M00236,M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14,3.A.1.3 Bacteria 47K9D@768503,4NEWY@976,COG1119@1,COG1119@2 NA|NA|NA P ABC-type molybdenum transport system ATPase component photorepair protein PhrA MAG.T22.3_02206 1305737.JAFX01000001_gene481 6.6e-100 370.5 Bacteroidetes Bacteria 4NJE7@976,COG3943@1,COG3943@2 NA|NA|NA S COG3943 Virulence protein MAG.T22.3_02207 1239962.C943_02865 8.2e-122 443.0 Cytophagia 3.1.3.16 ko:K07313 ko00000,ko01000 Bacteria 47SZE@768503,4NEQW@976,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase MAG.T22.3_02208 1123057.P872_07245 2.1e-60 238.8 Cytophagia Bacteria 2E07W@1,32VVR@2,47RC6@768503,4NSY6@976 NA|NA|NA S Domain of unknown function (DUF4136) MAG.T22.3_02209 1239962.C943_02867 2.1e-272 944.5 Cytophagia 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 47TFG@768503,4NIBJ@976,COG1472@1,COG1472@2 NA|NA|NA G Glycosyl hydrolase family 3 N terminal domain MAG.T22.3_02210 1239962.C943_02868 5.9e-60 236.9 Cytophagia Bacteria 47V2U@768503,4NPE1@976,COG5505@1,COG5505@2 NA|NA|NA S Protein of unknown function (DUF819) MAG.T22.3_02211 1239962.C943_03119 5.7e-186 656.8 Cytophagia 4.1.1.35 ko:K08678 ko00520,ko01100,map00520,map01100 M00361 R01384 RC00508 ko00000,ko00001,ko00002,ko01000 Bacteria 47JU8@768503,4NEZX@976,COG0451@1,COG0451@2 NA|NA|NA GM PFAM NAD dependent epimerase dehydratase family MAG.T22.3_02212 1239962.C943_03076 1e-282 978.8 Bacteroidetes Bacteria 4NZTV@976,COG5653@1,COG5653@2 NA|NA|NA M Acetyltransferase (GNAT) domain MAG.T22.3_02213 1239962.C943_03074 9.1e-135 486.5 Bacteria Bacteria COG0726@1,COG0726@2 NA|NA|NA G polysaccharide deacetylase MAG.T22.3_02214 1239962.C943_03073 1.3e-186 659.4 Bacteria Bacteria COG5653@1,COG5653@2 NA|NA|NA M Protein involved in cellulose biosynthesis MAG.T22.3_02215 1239962.C943_03071 1.2e-120 439.9 Bacteroidetes Bacteria 4NPX0@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.3_02216 1239962.C943_03070 1.9e-141 508.8 Bacteroidetes ko:K09726 ko00000 Bacteria 4NMZC@976,COG1817@1,COG1817@2 NA|NA|NA S Protein of unknown function (DUF354) MAG.T22.3_02217 1239962.C943_03068 2e-167 595.1 Bacteroidetes Bacteria 4NMHX@976,COG0438@1,COG0438@2 NA|NA|NA M Pfam Glycosyl transferases group 1 MAG.T22.3_02218 1239962.C943_03067 1e-148 533.1 Cytophagia Bacteria 47SFD@768503,4NKCQ@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.3_02220 880073.Calab_1316 1.2e-31 142.1 unclassified Bacteria cas2 ko:K09951 ko00000,ko02048 Bacteria 2NRWQ@2323,COG1343@1,COG1343@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette MAG.T22.3_02221 1048983.EL17_10925 4.3e-154 550.8 Cytophagia cas1 ko:K15342 ko00000,ko02048,ko03400 Bacteria 47NVK@768503,4NHKJ@976,COG1518@1,COG1518@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette MAG.T22.3_02222 714943.Mucpa_6528 3.4e-59 234.6 Sphingobacteriia cas4 3.1.12.1 ko:K07464 ko00000,ko01000,ko02048 Bacteria 1ISNM@117747,4NM54@976,COG1468@1,COG1468@2 NA|NA|NA L SPTR CRISPR-associated exonuclease, Cas4 family MAG.T22.3_02223 1121011.AUCB01000014_gene264 5.1e-170 605.1 Flavobacteriia cas3 ko:K07012 ko00000,ko01000,ko02048 Bacteria 1I6D3@117743,4NFZ0@976,COG1203@1,COG1203@2 NA|NA|NA L DEAD-like helicases superfamily MAG.T22.3_02224 709991.Odosp_1297 1.2e-58 233.4 Porphyromonadaceae cas5h ko:K19116 ko00000,ko02048 Bacteria 230N8@171551,28NN3@1,2FU9Y@200643,2ZBNI@2,4NP0Z@976 NA|NA|NA S TIGRFAM CRISPR-associated protein Cas5 MAG.T22.3_02225 1123058.KB894282_gene1659 3.8e-96 358.2 Bacteroidetes ko:K19115 ko00000,ko02048 Bacteria 4NIKJ@976,COG3649@1,COG3649@2 NA|NA|NA L PFAM CRISPR-associated protein TM1801 MAG.T22.3_02226 714943.Mucpa_6524 1.6e-114 420.2 Sphingobacteriia csh ko:K19114 ko00000,ko02048 Bacteria 1IUR2@117747,28JMD@1,2Z9DX@2,4NJJ1@976 NA|NA|NA MAG.T22.3_02227 1189612.A33Q_0883 2.4e-99 368.6 Cytophagia cas6 ko:K19091 ko00000,ko01000,ko02048 Bacteria 47QMP@768503,4NN1D@976,COG1583@1,COG1583@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) MAG.T22.3_02230 1239962.C943_02799 0.0 1252.7 Cytophagia Bacteria 47MR3@768503,4NEVN@976,COG2114@1,COG2114@2,COG3292@1,COG3292@2 NA|NA|NA T Belongs to the adenylyl cyclase class-4 guanylyl cyclase family MAG.T22.3_02231 1239962.C943_02803 2.4e-11 75.9 Cytophagia Bacteria 2BVZM@1,32QYM@2,47QFX@768503,4NQJT@976 NA|NA|NA MAG.T22.3_02232 1239962.C943_02803 2.7e-55 221.9 Cytophagia Bacteria 2BVZM@1,32QYM@2,47QFX@768503,4NQJT@976 NA|NA|NA MAG.T22.3_02233 1239962.C943_02804 4.3e-48 198.0 Bacteria Bacteria COG5164@1,COG5164@2 NA|NA|NA K cell wall organization MAG.T22.3_02234 1239962.C943_02805 0.0 1099.0 Cytophagia Bacteria 47QHE@768503,4NMRZ@976,COG4585@1,COG4585@2 NA|NA|NA T 7TMR-DISM extracellular 2 MAG.T22.3_02235 1239962.C943_02806 1.1e-107 396.0 Bacteria ko:K02282 ko00000,ko02035,ko02044 Bacteria COG2197@1,COG2197@2 NA|NA|NA K response regulator MAG.T22.3_02236 1239962.C943_02808 2.7e-15 87.8 Bacteria XK27_07760 Bacteria COG4980@1,COG4980@2 NA|NA|NA D gas vesicle protein MAG.T22.3_02239 1239962.C943_02062 2.7e-202 711.1 Cytophagia Bacteria 2CG1Y@1,2Z9QX@2,47PFJ@768503,4NJI6@976 NA|NA|NA S Protein of unknown function (DUF1573) MAG.T22.3_02240 1239962.C943_02061 6.9e-181 639.8 Cytophagia trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 47JNM@768503,4NETX@976,COG0180@1,COG0180@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family MAG.T22.3_02241 1239962.C943_02060 2.5e-217 761.1 Cytophagia argD 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 47JJU@768503,4NFMC@976,COG4992@1,COG4992@2 NA|NA|NA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family MAG.T22.3_02242 880071.Fleli_1646 1.2e-12 79.7 Cytophagia Bacteria 2EE0T@1,337VK@2,47SQ6@768503,4NWU8@976 NA|NA|NA MAG.T22.3_02243 926556.Echvi_2667 2.6e-170 605.1 Cytophagia Bacteria 47N9J@768503,4PKQ3@976,COG1506@1,COG1506@2 NA|NA|NA E Hydrolase Family 16 MAG.T22.3_02244 1034807.FBFL15_0730 3.1e-59 235.0 Flavobacteriia Bacteria 1I3ZC@117743,4NSGU@976,COG4337@1,COG4337@2 NA|NA|NA NU photosynthesis MAG.T22.3_02245 1239962.C943_02058 1.1e-131 476.1 Cytophagia Bacteria 47NHI@768503,4NKB3@976,COG2318@1,COG2318@2 NA|NA|NA S Mycothiol maleylpyruvate isomerase N-terminal domain MAG.T22.3_02246 1239962.C943_02057 0.0 1081.2 Cytophagia Bacteria 47KRM@768503,4NFTJ@976,COG0665@1,COG0665@2 NA|NA|NA E FAD dependent oxidoreductase MAG.T22.3_02247 1239962.C943_02056 7.9e-257 892.5 Cytophagia xylA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 iECO26_1355.ECO26_5036,iHN637.CLJU_RS08960,iPC815.YPO4038 Bacteria 47K9A@768503,4NEBQ@976,COG2115@1,COG2115@2 NA|NA|NA G Belongs to the xylose isomerase family MAG.T22.3_02248 1239962.C943_02055 5.6e-275 953.0 Cytophagia xylB GO:0003674,GO:0003824,GO:0004856,GO:0005975,GO:0005996,GO:0005997,GO:0005998,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:1901575 1.1.1.57,2.7.1.17 ko:K00040,ko:K00854,ko:K19168 ko00040,ko01100,map00040,map01100 M00014,M00061 R01639,R02454 RC00002,RC00085,RC00538 ko00000,ko00001,ko00002,ko01000,ko02048 iAPECO1_1312.APECO1_2885,iEC55989_1330.EC55989_4019,iECIAI1_1343.ECIAI1_3729,iECO103_1326.ECO103_4670,iECO111_1330.ECO111_4384,iECO26_1355.ECO26_5037,iECOK1_1307.ECOK1_4011,iECP_1309.ECP_3667,iECS88_1305.ECS88_3982,iECSE_1348.ECSE_3838,iECW_1372.ECW_m3838,iEKO11_1354.EKO11_0162,iUMN146_1321.UM146_17990,iUTI89_1310.UTI89_C4105,iWFL_1372.ECW_m3838,iYO844.BSU17610 Bacteria 47KIK@768503,4NFBZ@976,COG1070@1,COG1070@2 NA|NA|NA G PFAM FGGY family of carbohydrate kinases, N-terminal domain MAG.T22.3_02249 1239962.C943_02054 2.4e-295 1020.8 Cytophagia sglT ko:K03307 ko00000 2.A.21 Bacteria 47KIN@768503,4NE9S@976,COG4146@1,COG4146@2 NA|NA|NA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family MAG.T22.3_02251 1239962.C943_02053 0.0 1442.6 Cytophagia aguA GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010383,GO:0010410,GO:0010413,GO:0016052,GO:0016787,GO:0016798,GO:0033939,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044260,GO:0045491,GO:0045493,GO:0071554,GO:0071704,GO:1901575,GO:2000886 3.2.1.139 ko:K01235 ko00000,ko01000 Bacteria 47M6Y@768503,4NHE2@976,COG3661@1,COG3661@2 NA|NA|NA G Belongs to the glycosyl hydrolase 67 family MAG.T22.3_02252 1239962.C943_02052 1.3e-270 938.7 Cytophagia Bacteria 47M7Q@768503,4NDWS@976,COG4219@1,COG4219@2 NA|NA|NA KMT PFAM BlaR1 peptidase M56 MAG.T22.3_02253 1189612.A33Q_3929 5.8e-48 196.8 Cytophagia Bacteria 47QEY@768503,4NP4S@976,COG3682@1,COG3682@2 NA|NA|NA K Penicillinase repressor MAG.T22.3_02254 1239962.C943_02050 2.9e-122 444.9 Bacteroidetes Bacteria 2EAZB@1,33507@2,4NYHZ@976 NA|NA|NA MAG.T22.3_02255 1239962.C943_02049 5.8e-222 776.9 Bacteroidetes mucD 3.4.21.107 ko:K04771,ko:K07126 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 4NTKB@976,COG0265@1,COG0265@2 NA|NA|NA O Trypsin-like peptidase domain MAG.T22.3_02256 1239962.C943_02048 8.4e-265 919.1 Cytophagia Bacteria 47JKK@768503,4NEH3@976,COG1538@1,COG1538@2 NA|NA|NA MU PFAM Outer membrane efflux protein MAG.T22.3_02257 1239962.C943_02047 1.3e-249 868.6 Cytophagia cvaA Bacteria 47JV7@768503,4NFEK@976,COG0845@1,COG0845@2 NA|NA|NA M Biotin-lipoyl like MAG.T22.3_02258 1239962.C943_02046 1.7e-291 1008.1 Cytophagia ko:K02021 ko00000,ko02000 3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 Bacteria 47K3G@768503,4NFJF@976,COG2274@1,COG2274@2 NA|NA|NA V PFAM ABC transporter MAG.T22.3_02259 1239962.C943_02045 4.6e-115 420.6 Cytophagia Bacteria 47P97@768503,4NEUA@976,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family MAG.T22.3_02260 1239962.C943_02044 0.0 2065.8 Cytophagia ko:K08676 ko00000,ko01000,ko01002 Bacteria 47KCJ@768503,4NGU2@976,COG0793@1,COG0793@2,COG4946@1,COG4946@2 NA|NA|NA M Tricorn protease homolog MAG.T22.3_02261 459495.SPLC1_S204230 2e-14 85.1 Oscillatoriales Bacteria 1G8GS@1117,1HCSC@1150,COG4634@1,COG4634@2 NA|NA|NA MAG.T22.3_02262 661478.OP10G_3346 1.1e-20 105.5 Bacteria Bacteria COG2442@1,COG2442@2 NA|NA|NA K InterPro IPR007367 MAG.T22.3_02263 1239962.C943_02041 4.3e-147 527.3 Cytophagia Bacteria 47XEG@768503,4NFZB@976,COG2972@1,COG2972@2 NA|NA|NA T Histidine kinase MAG.T22.3_02264 1239962.C943_02040 2.2e-123 448.4 Cytophagia ko:K02477 ko00000,ko02022 Bacteria 47XE8@768503,4NPFH@976,COG3279@1,COG3279@2 NA|NA|NA KT LytTr DNA-binding domain MAG.T22.3_02269 1239962.C943_02034 3.3e-131 474.6 Cytophagia Bacteria 47NN7@768503,4NGAF@976,COG0657@1,COG0657@2 NA|NA|NA I Protein of unknown function (DUF1460) MAG.T22.3_02270 357808.RoseRS_1319 1e-119 436.8 Chloroflexia ko:K02057 M00221 ko00000,ko00002,ko02000 3.A.1.2 Bacteria 2G6MU@200795,375FD@32061,COG4603@1,COG4603@2 NA|NA|NA S Belongs to the binding-protein-dependent transport system permease family MAG.T22.3_02271 357808.RoseRS_1320 6.8e-124 450.7 Chloroflexia ko:K07335 ko00000 Bacteria 2G6UB@200795,375H7@32061,COG1744@1,COG1744@2 NA|NA|NA M PFAM basic membrane lipoprotein MAG.T22.3_02272 1239962.C943_01522 1.7e-111 409.1 Cytophagia ttg2C ko:K02067 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 47MRD@768503,4NGHE@976,COG1463@1,COG1463@2 NA|NA|NA Q ABC-type transport system involved in resistance to organic solvents periplasmic component MAG.T22.3_02273 1239962.C943_01521 9.6e-217 759.2 Cytophagia Bacteria 47U8Y@768503,4NM79@976,COG0025@1,COG0025@2 NA|NA|NA P Sodium/hydrogen exchanger family MAG.T22.3_02275 1239962.C943_01520 1.4e-112 412.1 Cytophagia cccE Bacteria 47QS4@768503,4NQXA@976,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T22.3_02276 1239962.C943_01518 2.8e-108 397.9 Bacteroidetes Bacteria 4NV5A@976,COG4636@1,COG4636@2 NA|NA|NA S COGs COG4636 conserved MAG.T22.3_02277 1239962.C943_01517 5.3e-226 790.0 Cytophagia ko:K14358 ko00000,ko01002 Bacteria 47TU7@768503,4PAJB@976,COG4690@1,COG4690@2 NA|NA|NA E Peptidase family C69 MAG.T22.3_02278 1239962.C943_01515 4.3e-77 293.9 Cytophagia 4.4.1.5 ko:K01759 ko00620,map00620 R02530 RC00004,RC00740 ko00000,ko00001,ko01000 Bacteria 47RDB@768503,4NSC9@976,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase-like domain MAG.T22.3_02279 1239962.C943_01513 1.4e-306 1058.1 Cytophagia ctp 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 47JP7@768503,4NEGV@976,COG0793@1,COG0793@2 NA|NA|NA M Belongs to the peptidase S41A family MAG.T22.3_02280 1239962.C943_01512 3e-131 474.6 Cytophagia hcp 1.7.99.1 ko:K05601,ko:K07322 ko00910,map00910 R00143 RC02797 ko00000,ko00001,ko01000 Bacteria 47PY2@768503,4NPQ7@976,COG2846@1,COG2846@2 NA|NA|NA D Di-iron-containing protein involved in the repair of iron-sulfur clusters MAG.T22.3_02281 1239962.C943_01511 4.5e-65 253.8 Cytophagia yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 47QCM@768503,4NQ8B@976,COG0816@1,COG0816@2 NA|NA|NA L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA MAG.T22.3_02282 1239962.C943_01510 6.8e-101 373.2 Cytophagia def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 ko00000,ko01000 Bacteria 47JIG@768503,4NFB4@976,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions MAG.T22.3_02283 1239962.C943_01509 1.3e-145 522.3 Cytophagia yafV 3.5.1.3 ko:K13566 ko00250,map00250 R00269,R00348 RC00010 ko00000,ko00001,ko01000 Bacteria 47JPF@768503,4NE37@976,COG0388@1,COG0388@2 NA|NA|NA S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase MAG.T22.3_02286 289376.THEYE_A0309 9.6e-16 89.0 Nitrospirae Bacteria 3J1A5@40117,COG1598@1,COG1598@2 NA|NA|NA S HicB_like antitoxin of bacterial toxin-antitoxin system MAG.T22.3_02287 1120951.AUBG01000007_gene14 1.9e-17 95.9 Bacteria ko:K03686,ko:K05801,ko:K17867 ko00000,ko03012,ko03029,ko03110 Bacteria COG0484@1,COG0484@2 NA|NA|NA O heat shock protein binding MAG.T22.3_02290 1239962.C943_04060 4.4e-227 793.5 Cytophagia 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 R01183,R09951 RC00182 ko00000,ko00001,ko01000 Bacteria 47NZU@768503,4NG5E@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.3_02291 1239962.C943_04059 9.7e-202 709.1 Cytophagia Bacteria 47N5G@768503,4NFSP@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T22.3_02292 1239962.C943_04058 2.7e-243 847.4 Cytophagia Bacteria 47NZ6@768503,4NGGP@976,COG1482@1,COG1482@2 NA|NA|NA G cell wall glycoprotein biosynthetic process MAG.T22.3_02293 1239962.C943_04057 1.8e-203 714.9 Cytophagia Bacteria 47JMF@768503,4NHQH@976,COG2017@1,COG2017@2 NA|NA|NA G Domain of unknown function (DUF4432) MAG.T22.3_02294 1239962.C943_04056 6.4e-137 493.4 Bacteroidetes 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria 4NFXB@976,COG2133@1,COG2133@2 NA|NA|NA G Domain of Unknown Function (DUF1080) MAG.T22.3_02295 1239962.C943_04055 0.0 1679.1 Cytophagia Bacteria 47K4F@768503,4NH6W@976,COG2133@1,COG2133@2 NA|NA|NA CG Cytochrome c MAG.T22.3_02296 1239962.C943_04054 1.3e-273 948.3 Cytophagia Bacteria 47MMC@768503,4NGYE@976,COG3119@1,COG3119@2 NA|NA|NA P Protein of unknown function (DUF1501) MAG.T22.3_02297 1239962.C943_04053 0.0 1533.5 Cytophagia Bacteria 47K0Y@768503,4NG6K@976,COG4244@1,COG4244@2 NA|NA|NA G Protein of unknown function (DUF1549) MAG.T22.3_02298 1239962.C943_04051 0.0 2094.7 Cytophagia 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 47MTS@768503,4NEQA@976,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2,COG2755@1,COG2755@2 NA|NA|NA C HEAT repeats MAG.T22.3_02299 1189612.A33Q_0139 7.7e-13 80.5 Cytophagia Bacteria 2EJAG@1,33D1N@2,47SXP@768503,4NZ69@976 NA|NA|NA MAG.T22.3_02301 1239962.C943_01523 6e-132 476.9 Cytophagia mkl ko:K02065 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 47XJE@768503,4NETG@976,COG1127@1,COG1127@2 NA|NA|NA Q ATPases associated with a variety of cellular activities MAG.T22.3_02302 1239962.C943_01524 2.9e-137 494.6 Cytophagia ko:K02066 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 47K33@768503,4NF7X@976,COG0767@1,COG0767@2 NA|NA|NA Q ABC-type transport system involved in resistance to organic solvents permease component MAG.T22.3_02303 1239962.C943_01525 9e-65 252.7 Bacteroidetes Bacteria 4P49T@976,COG3437@1,COG3437@2 NA|NA|NA T PFAM Response regulator receiver domain MAG.T22.3_02304 1239962.C943_01527 6e-69 266.9 Cytophagia Bacteria 47RAX@768503,4NNMS@976,COG2350@1,COG2350@2 NA|NA|NA S YCII-related domain MAG.T22.3_02305 1239962.C943_01528 1.4e-245 855.1 Cytophagia Bacteria 47MBV@768503,4NE09@976,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T22.3_02306 1239962.C943_01529 8.5e-170 602.8 Cytophagia 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 47MNW@768503,4NGFK@976,COG0524@1,COG0524@2 NA|NA|NA G PfkB domain protein MAG.T22.3_02307 1239962.C943_01530 3.5e-244 850.5 Cytophagia ko:K07148 ko00000 Bacteria 47JP8@768503,4NG01@976,COG2311@1,COG2311@2 NA|NA|NA S Protein of unknown function (DUF418) MAG.T22.3_02308 1239962.C943_01531 3.4e-95 354.4 Bacteroidetes Bacteria 2CMS6@1,32SFE@2,4NWI0@976 NA|NA|NA MAG.T22.3_02309 1239962.C943_01532 0.0 1397.5 Cytophagia ptrB GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Bacteria 47KWW@768503,4NEQS@976,COG1770@1,COG1770@2 NA|NA|NA E PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain MAG.T22.3_02310 1239962.C943_01533 2.4e-221 774.6 Cytophagia Bacteria 28HUE@1,2Z815@2,47P5G@768503,4NHK5@976 NA|NA|NA MAG.T22.3_02313 1239962.C943_01535 5.3e-86 323.6 Bacteroidetes Bacteria 4NSE3@976,COG2010@1,COG2010@2 NA|NA|NA C Haem-binding domain MAG.T22.3_02314 1239962.C943_01536 2.3e-265 921.0 Cytophagia pyk GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iAF987.Gmet_0122 Bacteria 47JS3@768503,4NEEU@976,COG0469@1,COG0469@2 NA|NA|NA G Belongs to the pyruvate kinase family MAG.T22.3_02315 1239962.C943_01537 3.5e-73 280.8 Cytophagia Bacteria 2DNED@1,32UIS@2,47RRD@768503,4NUJS@976 NA|NA|NA MAG.T22.3_02316 1123057.P872_01180 1.2e-33 148.7 Cytophagia acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 47R56@768503,4NS6C@976,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis MAG.T22.3_02317 1239962.C943_01539 2.1e-235 821.2 Cytophagia fabF 2.3.1.179 ko:K09458,ko:K14660 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 iSB619.SA_RS04785 Bacteria 47MQI@768503,4NEKC@976,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP MAG.T22.3_02318 1239962.C943_01540 2.1e-117 428.3 Cytophagia rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 47K17@768503,4NE0N@976,COG0571@1,COG0571@2 NA|NA|NA J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism MAG.T22.3_02319 1239962.C943_01541 0.0 1213.7 Cytophagia nadE GO:0003674,GO:0003824,GO:0003952,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 Bacteria 47JFU@768503,4NHXQ@976,COG0171@1,COG0171@2,COG0388@1,COG0388@2 NA|NA|NA H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source MAG.T22.3_02320 1239962.C943_01542 2.4e-209 734.6 Cytophagia lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 47KQC@768503,4NFP7@976,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins MAG.T22.3_02321 1239962.C943_01544 2.5e-283 980.7 Cytophagia Bacteria 47KUK@768503,4NF9Y@976,COG4775@1,COG4775@2 NA|NA|NA M PFAM surface antigen variable number repeat MAG.T22.3_02322 1239962.C943_01546 9.1e-134 483.0 Cytophagia comEA ko:K02237 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 47Q92@768503,4NQC1@976,COG1555@1,COG1555@2 NA|NA|NA L photosystem II stabilization MAG.T22.3_02323 1239962.C943_01547 0.0 1380.2 Cytophagia comEA ko:K02237 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 47KA3@768503,4NE88@976,COG1555@1,COG1555@2 NA|NA|NA L Helix-hairpin-helix motif MAG.T22.3_02324 1239962.C943_01548 0.0 1583.9 Cytophagia Bacteria 47JTT@768503,4PMAZ@976,COG1913@1,COG1913@2 NA|NA|NA S Domain of unknown function (DUF5117) MAG.T22.3_02325 1239962.C943_01549 2.9e-157 561.2 Cytophagia ko:K09164 ko00000 Bacteria 47NJY@768503,4NFT3@976,COG3358@1,COG3358@2 NA|NA|NA S Protein of unknown function (DUF1684) MAG.T22.3_02326 1239962.C943_01550 4.8e-145 520.4 Cytophagia 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria 47K5J@768503,4NK4E@976,COG2133@1,COG2133@2 NA|NA|NA G Domain of Unknown Function (DUF1080) MAG.T22.3_02327 1239962.C943_01551 1.7e-119 435.3 Bacteroidetes Bacteria 4PMQQ@976,COG1357@1,COG1357@2 NA|NA|NA UW Protein of unknown function (DUF1566) MAG.T22.3_02328 1239962.C943_01552 3.6e-137 494.2 Cytophagia ecsC Bacteria 28I6D@1,2Z89E@2,47MYZ@768503,4NIIX@976 NA|NA|NA S EcsC protein family MAG.T22.3_02329 1123057.P872_07285 1.2e-29 136.0 Cytophagia Bacteria 47RUA@768503,4NQ3Z@976,COG4068@1,COG4068@2 NA|NA|NA MAG.T22.3_02330 1239962.C943_01554 0.0 1259.2 Cytophagia Bacteria 47NS1@768503,4NFTM@976,COG0823@1,COG0823@2,COG1506@1,COG1506@2 NA|NA|NA EU Dienelactone hydrolase family MAG.T22.3_02331 1239962.C943_01555 6.5e-64 250.4 Bacteroidetes Bacteria 2DD3M@1,2ZGBQ@2,4P80Y@976 NA|NA|NA MAG.T22.3_02332 1239962.C943_01556 0.0 1331.6 Cytophagia hppA 3.6.1.1 ko:K15987 ko00190,map00190 ko00000,ko00001,ko01000 3.A.10.1 Bacteria 47MRY@768503,4NF2I@976,COG3808@1,COG3808@2 NA|NA|NA C Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane MAG.T22.3_02333 1239962.C943_01557 0.0 1901.3 Cytophagia MA20_43170 ko:K06911 ko00000 Bacteria 47JNC@768503,4NEK3@976,COG0247@1,COG0247@2,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain MAG.T22.3_02334 1239962.C943_02640 5.9e-191 673.3 Cytophagia hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 iPC815.YPO3734,iSBO_1134.SBO_4018 Bacteria 47K90@768503,4NEQ7@976,COG0407@1,COG0407@2 NA|NA|NA H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III MAG.T22.3_02335 1239962.C943_02639 1.9e-55 222.2 Bacteroidetes Bacteria 2DI3V@1,32UAD@2,4NUQE@976 NA|NA|NA MAG.T22.3_02336 1048983.EL17_13460 1.4e-24 119.8 Cytophagia Bacteria 2EI7N@1,33BZ0@2,47SQG@768503,4NXIG@976 NA|NA|NA MAG.T22.3_02338 1239962.C943_02635 0.0 1131.7 Cytophagia MdlB ko:K06147,ko:K18890 ko02010,map02010 M00707 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 Bacteria 47JVG@768503,4NEAG@976,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region MAG.T22.3_02339 1239962.C943_02634 3.6e-145 520.8 Cytophagia truA GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 47KUM@768503,4NFDC@976,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs MAG.T22.3_02340 1239962.C943_02633 1.2e-74 285.8 Cytophagia Bacteria 2AVDM@1,31M58@2,47RZW@768503,4P9SJ@976 NA|NA|NA S Domain of unknown function (DUF4293) MAG.T22.3_02341 1239962.C943_02631 1.8e-201 708.4 Cytophagia metB 2.5.1.48,4.4.1.8 ko:K01739,ko:K01760,ko:K21173 ko00270,ko00450,ko00920,ko01059,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01059,map01100,map01110,map01130,map01230 M00017,M00825 R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 Bacteria 47JY2@768503,4NF0Q@976,COG0626@1,COG0626@2 NA|NA|NA E PFAM Cys Met metabolism PLP-dependent enzyme MAG.T22.3_02342 1239962.C943_02630 9.2e-289 998.8 Cytophagia comM ko:K07391 ko00000 Bacteria 47MUV@768503,4NE0G@976,COG0606@1,COG0606@2 NA|NA|NA O magnesium chelatase MAG.T22.3_02343 1123057.P872_24030 5.2e-25 120.6 Cytophagia Bacteria 2EVBB@1,33ZHX@2,47VEU@768503,4P4C3@976 NA|NA|NA MAG.T22.3_02344 1239962.C943_02628 0.0 1136.3 Cytophagia msbA ko:K02021,ko:K06147,ko:K06148,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 Bacteria 47JQI@768503,4NE2D@976,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region MAG.T22.3_02345 1434325.AZQN01000014_gene1355 6e-57 229.6 Cytophagia Bacteria 47RTZ@768503,4NJMQ@976,COG1075@1,COG1075@2 NA|NA|NA S acetyltransferases and hydrolases with the alpha beta hydrolase fold MAG.T22.3_02348 1189612.A33Q_0853 1.2e-31 143.3 Cytophagia Bacteria 2AFVR@1,315YE@2,47SSJ@768503,4PK8B@976 NA|NA|NA MAG.T22.3_02350 1239962.C943_02627 0.0 1126.3 Cytophagia Bacteria 2DBCF@1,2Z8DB@2,47JNN@768503,4NG6B@976 NA|NA|NA MAG.T22.3_02352 1239962.C943_02623 5.6e-39 166.4 Cytophagia rpmE2 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47R60@768503,4NS7P@976,COG0254@1,COG0254@2 NA|NA|NA J Ribosomal protein L31 MAG.T22.3_02353 1239962.C943_02622 2.9e-229 800.8 Cytophagia glmU 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 47XWC@768503,4NDZP@976,COG1207@1,COG1207@2 NA|NA|NA M Sugar nucleotidyl transferase MAG.T22.3_02354 1239962.C943_02621 1.7e-202 711.8 Cytophagia holB 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 47KBY@768503,4PKEA@976,COG2812@1,COG2812@2 NA|NA|NA L DNA polymerase III, delta subunit MAG.T22.3_02355 1239962.C943_02620 9.4e-74 282.7 Cytophagia Bacteria 47RH0@768503,4NS86@976,COG4067@1,COG4067@2 NA|NA|NA O Putative ATP-dependant zinc protease MAG.T22.3_02356 1239962.C943_02619 3.1e-162 577.8 Cytophagia rimK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 6.3.1.17,6.3.2.32,6.3.2.41 ko:K05844,ko:K14940,ko:K18310 ko00250,ko00680,ko01100,ko01120,map00250,map00680,map01100,map01120 R09401,R10677,R10678 RC00064,RC00090,RC00141,RC03233 ko00000,ko00001,ko01000,ko03009 Bacteria 47KJX@768503,4NED4@976,COG0189@1,COG0189@2 NA|NA|NA HJ Belongs to the RimK family MAG.T22.3_02357 1239962.C943_02618 5.6e-156 557.0 Cytophagia hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 ko:K01749,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084,R03165,R03194 RC00003,RC00871,RC01861,RC02317 ko00000,ko00001,ko00002,ko01000 iEC55989_1330.EC55989_4275,iECH74115_1262.ECH74115_5243,iECIAI1_1343.ECIAI1_3991,iECO103_1326.ECO103_4362,iECO111_1330.ECO111_4628,iECO26_1355.ECO26_4784,iECSE_1348.ECSE_4086,iEKO11_1354.EKO11_4554,iHN637.CLJU_RS15760,iPC815.YPO3849 Bacteria 47M9Y@768503,4NHH4@976,COG0181@1,COG0181@2 NA|NA|NA H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps MAG.T22.3_02358 1239962.C943_02617 1.1e-142 512.7 Cytophagia 5.2.1.8 ko:K01802,ko:K03768 ko00000,ko01000,ko03110 Bacteria 47MY6@768503,4NGT6@976,COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides MAG.T22.3_02359 1239962.C943_02616 7e-159 566.6 Cytophagia rmlD 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 Bacteria 47MQV@768503,4NE3K@976,COG1091@1,COG1091@2 NA|NA|NA M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose MAG.T22.3_02360 1189612.A33Q_0752 4.3e-221 773.9 Cytophagia yocR ko:K03308 ko00000 2.A.22.4,2.A.22.5 Bacteria 47NFV@768503,4NGQ5@976,COG0733@1,COG0733@2 NA|NA|NA U Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family MAG.T22.3_02361 1239962.C943_02614 3.6e-58 230.7 Bacteria vieS 2.7.13.3 ko:K07677,ko:K07679,ko:K20974 ko02020,ko02025,ko02026,ko05133,map02020,map02025,map02026,map05133 M00474,M00477,M00820 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria COG0784@1,COG0784@2 NA|NA|NA T Response regulator, receiver MAG.T22.3_02362 1239962.C943_02613 2.5e-98 364.8 Cytophagia Bacteria 47RP0@768503,4NVY6@976,COG3637@1,COG3637@2 NA|NA|NA M Outer membrane protein beta-barrel domain MAG.T22.3_02363 1239962.C943_02612 0.0 1738.0 Cytophagia Bacteria 47NMF@768503,4NESU@976,COG4447@1,COG4447@2 NA|NA|NA G Sortilin, neurotensin receptor 3, MAG.T22.3_02364 1239962.C943_02611 2e-40 171.4 Cytophagia divIC ko:K05589,ko:K12065,ko:K13052 ko00000,ko02044,ko03036 3.A.7.11.1 Bacteria 47S83@768503,4P9WW@976,COG2919@1,COG2919@2 NA|NA|NA D Septum formation initiator MAG.T22.3_02365 1239962.C943_02610 1.9e-92 345.1 Cytophagia Bacteria 28NMY@1,2ZBNE@2,47YAY@768503,4NN50@976 NA|NA|NA MAG.T22.3_02366 1239962.C943_02609 2.7e-141 508.1 Cytophagia cysE 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 Bacteria 47JAY@768503,4NGZ7@976,COG1045@1,COG1045@2 NA|NA|NA E serine acetyltransferase MAG.T22.3_02367 1239962.C943_02608 7.3e-158 563.1 Cytophagia cysM GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0080146,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K01738,ko:K12339 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03132,R03601,R04859 RC00020,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000 iECP_1309.ECP_2444 Bacteria 47J9D@768503,4NF7E@976,COG0031@1,COG0031@2 NA|NA|NA E Belongs to the cysteine synthase cystathionine beta- synthase family MAG.T22.3_02368 1239962.C943_02607 1.9e-269 934.5 Cytophagia Bacteria 47N60@768503,4NDYI@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.3_02369 1120965.AUBV01000003_gene633 5e-09 66.6 Cytophagia Bacteria 2EN4F@1,33FSI@2,47WGB@768503,4NY0E@976 NA|NA|NA MAG.T22.3_02370 1239962.C943_02606 3.2e-203 714.1 Cytophagia comC 1.1.1.350 ko:K00073 ko00230,ko01120,map00230,map01120 R02935,R02936 RC00169 ko00000,ko00001,ko01000 Bacteria 47KBZ@768503,4NGVC@976,COG2055@1,COG2055@2 NA|NA|NA C Belongs to the LDH2 MDH2 oxidoreductase family MAG.T22.3_02371 1239962.C943_02605 5.5e-159 567.0 Cytophagia gppA-2 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 47K3H@768503,4NH03@976,COG0248@1,COG0248@2 NA|NA|NA FP Ppx GppA phosphatase MAG.T22.3_02373 1239962.C943_02603 1.4e-300 1038.1 Cytophagia pccB 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 Bacteria 47K3E@768503,4NEMJ@976,COG4799@1,COG4799@2 NA|NA|NA I Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) MAG.T22.3_02374 1239962.C943_02601 1.2e-197 695.7 Cytophagia frvX 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 47MIG@768503,4NG97@976,COG1363@1,COG1363@2 NA|NA|NA G PFAM M42 glutamyl aminopeptidase MAG.T22.3_02375 1239962.C943_02600 2.5e-114 418.3 Cytophagia fecB ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 47M03@768503,4NI2Y@976,COG0614@1,COG0614@2 NA|NA|NA P Periplasmic binding protein MAG.T22.3_02376 1239962.C943_02599 8.4e-262 909.1 Cytophagia Bacteria 47M9C@768503,4NF4Q@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase domain protein MAG.T22.3_02377 1239962.C943_02598 2.7e-140 504.6 Cytophagia 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria 47PH9@768503,4NIMV@976,COG2133@1,COG2133@2 NA|NA|NA G Domain of Unknown Function (DUF1080) MAG.T22.3_02378 1239962.C943_02597 8.2e-108 396.4 Cytophagia Bacteria 47P9Y@768503,4NFKF@976,COG1082@1,COG1082@2 NA|NA|NA G Domain of Unknown Function (DUF1080) MAG.T22.3_02379 1239962.C943_03077 9.4e-233 812.4 Cytophagia Bacteria 47MAS@768503,4NJ92@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.3_02380 1239962.C943_03078 9.1e-18 96.3 Cytophagia Bacteria 2DYHN@1,349SE@2,47W89@768503,4P6BJ@976 NA|NA|NA MAG.T22.3_02381 1239962.C943_03079 3.4e-115 421.0 Cytophagia Bacteria 2BB8B@1,324R0@2,47RS3@768503,4NQG8@976 NA|NA|NA MAG.T22.3_02382 1239962.C943_03080 0.0 1089.7 Cytophagia mdlA ko:K06147,ko:K18889 ko02010,map02010 M00707 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 Bacteria 47JPX@768503,4NDY6@976,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region MAG.T22.3_02383 1239962.C943_03081 1.4e-206 725.3 Cytophagia ldh 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 Bacteria 47MHP@768503,4NF3I@976,COG0334@1,COG0334@2 NA|NA|NA E Belongs to the Glu Leu Phe Val dehydrogenases family MAG.T22.3_02384 1239962.C943_03082 3.7e-213 747.3 Cytophagia nusB ko:K03625 ko00000,ko03009,ko03021 Bacteria 47M4A@768503,4NDVR@976,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons MAG.T22.3_02385 1239962.C943_03083 2.5e-41 174.5 Cytophagia XK27_07760 Bacteria 47RXK@768503,4NVHP@976,COG4980@1,COG4980@2 NA|NA|NA S YtxH-like protein MAG.T22.3_02386 1239962.C943_03084 5.1e-93 347.1 Cytophagia ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 47R1B@768503,4NP5H@976,COG2885@1,COG2885@2 NA|NA|NA M Protein of unknown function (DUF1573) MAG.T22.3_02387 1239962.C943_03085 2.6e-49 201.1 Cytophagia yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 47R3A@768503,4NUT4@976,COG1862@1,COG1862@2 NA|NA|NA U TIGRFAM preprotein translocase, YajC subunit MAG.T22.3_02388 1239962.C943_03086 5.4e-178 630.2 Cytophagia ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 Bacteria 47K4N@768503,4NK5K@976,COG4856@1,COG4856@2 NA|NA|NA S YbbR-like protein MAG.T22.3_02389 1239962.C943_03087 2.3e-102 378.3 Cytophagia coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,2.7.7.87 ko:K00859,ko:K07566 ko00770,ko01100,map00770,map01100 M00120 R00130,R10463 RC00002,RC00078,RC00745 ko00000,ko00001,ko00002,ko01000,ko03009,ko03016 Bacteria 47P6S@768503,4NQKS@976,COG0237@1,COG0237@2 NA|NA|NA H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A MAG.T22.3_02390 1120965.AUBV01000004_gene674 4.7e-30 136.7 Cytophagia Bacteria 2EDEU@1,337B5@2,47SHQ@768503,4NVH5@976 NA|NA|NA MAG.T22.3_02391 1239962.C943_03089 1.6e-180 638.6 Cytophagia Bacteria 47N78@768503,4NJ7M@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.3_02392 1239962.C943_03090 1.2e-85 322.4 Cytophagia nlpC ko:K13695 ko00000,ko01002 Bacteria 47PEH@768503,4NSZJ@976,COG0791@1,COG0791@2 NA|NA|NA M Cell wall-associated hydrolase (invasion-associated protein) MAG.T22.3_02393 1239962.C943_03091 9.1e-107 392.9 Cytophagia Bacteria 2DBWZ@1,2ZBKJ@2,47PF3@768503,4NMS8@976 NA|NA|NA S HmuY protein MAG.T22.3_02394 1239962.C943_03092 0.0 1455.3 Cytophagia ko:K16089 ko00000,ko02000 1.B.14.1,1.B.14.10 Bacteria 47YGD@768503,4PKKN@976,COG4206@1,COG4206@2 NA|NA|NA H TonB dependent receptor MAG.T22.3_02395 1239962.C943_03093 5.3e-187 660.2 Cytophagia hmuS ko:K02016,ko:K07225 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 47MSN@768503,4NEZU@976,COG3720@1,COG3720@2 NA|NA|NA P heme degradation protein MAG.T22.3_02396 1239962.C943_03094 7.9e-143 513.1 Cytophagia hmuV 1.14.15.20,3.6.3.34 ko:K02013,ko:K21480 ko00860,ko01100,ko01110,ko02010,map00860,map01100,map01110,map02010 M00240 R11579 RC01270 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 Bacteria 47PKH@768503,4NK28@976,COG4559@1,COG4559@2 NA|NA|NA P Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system MAG.T22.3_02397 1239962.C943_03095 9.1e-159 566.2 Cytophagia hmuU ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 47JPP@768503,4NEDU@976,COG0609@1,COG0609@2 NA|NA|NA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily MAG.T22.3_02398 869213.JCM21142_41922 3.6e-88 331.6 Cytophagia tupA Bacteria 47U7W@768503,4NHYZ@976,COG0189@1,COG0189@2 NA|NA|NA HJ ligase activity MAG.T22.3_02399 1121889.AUDM01000003_gene2406 1.7e-83 318.2 Flavobacterium Bacteria 1IKDI@117743,2P0DY@237,4PKPT@976,COG3386@1,COG3386@2,COG4886@1,COG4886@2 NA|NA|NA G Domain of unknown function (DUF5122) beta-propeller MAG.T22.3_02400 1239962.C943_03067 5.6e-88 331.3 Cytophagia Bacteria 47SFD@768503,4NKCQ@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.3_02401 1239962.C943_01342 0.0 2197.2 Cytophagia pel ko:K21449 ko00000,ko02000 1.B.40.2 Bacteria 47SGI@768503,4NXBV@976,COG3055@1,COG3055@2,COG3291@1,COG3291@2,COG3866@1,COG3866@2,COG4733@1,COG4733@2 NA|NA|NA G Fibronectin type 3 domain MAG.T22.3_02402 880070.Cycma_0727 2.2e-215 757.3 Cytophagia Bacteria 47K9E@768503,4NHHD@976,COG3055@1,COG3055@2 NA|NA|NA S Kelch repeat MAG.T22.3_02403 313603.FB2170_09981 3.5e-87 327.8 Maribacter 2.3.1.79 ko:K00661 ko00000,ko01000 Bacteria 1IG5F@117743,2PIVK@252356,4PISH@976,COG0110@1,COG0110@2 NA|NA|NA S Hexapeptide repeat of succinyl-transferase MAG.T22.3_02405 1239962.C943_01339 0.0 2165.6 Bacteria pel Bacteria COG3866@1,COG3866@2,COG4254@1,COG4254@2,COG5492@1,COG5492@2 NA|NA|NA UW PFAM FecR protein MAG.T22.3_02406 1239962.C943_01337 8.9e-89 334.0 Bacteroidetes Bacteria 2DX4H@1,32V2S@2,4NWQ8@976 NA|NA|NA MAG.T22.3_02407 1239962.C943_01336 1.2e-200 706.1 Bacteria pel Bacteria COG3866@1,COG3866@2 NA|NA|NA G Pectate lyase MAG.T22.3_02410 1239962.C943_03873 4.2e-37 160.2 Cytophagia Bacteria 2C9V5@1,2Z8F9@2,47S8V@768503,4NG2N@976 NA|NA|NA MAG.T22.3_02413 1239962.C943_03876 2.1e-26 124.4 Cytophagia Bacteria 2DP5Z@1,330NW@2,47SP6@768503,4NV0Q@976 NA|NA|NA MAG.T22.3_02415 1237149.C900_02128 2.5e-57 231.1 Bacteria Bacteria COG3209@1,COG3209@2 NA|NA|NA M self proteolysis MAG.T22.3_02416 1288963.ADIS_1277 8.7e-289 1000.3 Cytophagia Bacteria 47KAA@768503,4NE5D@976,COG3209@1,COG3209@2 NA|NA|NA M TIGRFAM RHS repeat-associated core domain MAG.T22.3_02419 1239962.C943_02363 8.8e-281 972.2 Cytophagia glyQS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iSB619.SA_RS07880 Bacteria 47MCS@768503,4NE1C@976,COG0423@1,COG0423@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family MAG.T22.3_02421 1239962.C943_02365 3.2e-283 980.3 Cytophagia crtD 1.3.99.26,1.3.99.27,1.3.99.28,1.3.99.29,1.3.99.31,5.4.99.9 ko:K01854,ko:K09845,ko:K10027 ko00052,ko00520,ko00906,ko01100,ko01110,map00052,map00520,map00906,map01100,map01110 R00505,R04787,R04798,R04800,R07517,R07520,R07523,R07534,R09009,R09691,R09692 RC00317,RC01214,RC02080,RC02088,RC02396,RC02605 ko00000,ko00001,ko01000 Bacteria 47MT8@768503,4NG7V@976,COG1233@1,COG1233@2 NA|NA|NA Q phytoene MAG.T22.3_02422 1239962.C943_02366 0.0 1686.4 Cytophagia ko:K14054 ko00000 Bacteria 47KZ0@768503,4NEJA@976,COG2866@1,COG2866@2 NA|NA|NA E PFAM Zinc carboxypeptidase MAG.T22.3_02423 866536.Belba_1508 4.8e-16 89.7 Cytophagia Bacteria 2AHAZ@1,317MB@2,47WKR@768503,4P8SC@976 NA|NA|NA S Phospholipase_D-nuclease N-terminal MAG.T22.3_02424 1239962.C943_02372 7.7e-155 553.1 Cytophagia yfcH ko:K07071 ko00000 Bacteria 47KA1@768503,4NINM@976,COG1090@1,COG1090@2 NA|NA|NA S PFAM NAD dependent epimerase dehydratase family MAG.T22.3_02425 1239962.C943_02373 2.8e-58 231.1 Cytophagia crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 47RZJ@768503,4NV3N@976,COG0239@1,COG0239@2 NA|NA|NA D Important for reducing fluoride concentration in the cell, thus reducing its toxicity MAG.T22.3_02426 1239962.C943_02374 1.9e-156 558.5 Bacteroidetes yafP 1.17.1.8,2.3.1.82,3.6.4.13 ko:K00215,ko:K00663,ko:K03578,ko:K03830 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 4NR84@976,COG0454@1,COG0456@2,COG1670@1,COG1670@2 NA|NA|NA K Acetyltransferase (GNAT) domain MAG.T22.3_02427 1239962.C943_02375 2.7e-114 417.9 Cytophagia pnuC ko:K03811 ko00000,ko02000 4.B.1.1 Bacteria 47R6S@768503,4NFJI@976,COG3201@1,COG3201@2 NA|NA|NA H TIGRFAM Nicotinamide mononucleotide transporter PnuC MAG.T22.3_02428 1239962.C943_02376 2.5e-84 318.2 Cytophagia nadR Bacteria 47QMU@768503,4NFNZ@976,COG3172@1,COG3172@2 NA|NA|NA H ATPase kinase involved in NAD metabolism MAG.T22.3_02429 1239962.C943_02377 7.5e-86 323.2 Cytophagia Bacteria 29QR1@1,30BQU@2,47PZC@768503,4NNQY@976 NA|NA|NA MAG.T22.3_02430 1239962.C943_02378 8.5e-201 706.1 Cytophagia desD 1.14.19.3 ko:K00508 ko00591,ko01100,map00591,map01100 R07063 RC00917 ko00000,ko00001,ko01000,ko01004 iJN678.desD_des6_ Bacteria 47NRC@768503,4NERD@976,COG3239@1,COG3239@2 NA|NA|NA I fatty acid desaturase MAG.T22.3_02431 1239962.C943_02379 0.0 1572.4 Cytophagia ko:K02014 ko00000,ko02000 1.B.14 Bacteria 47KHE@768503,4PKTE@976,COG4772@1,COG4772@2 NA|NA|NA P PFAM TonB-dependent Receptor Plug Domain MAG.T22.3_02433 1239962.C943_02382 1.8e-99 368.6 Cytophagia Bacteria 2E57P@1,33006@2,47SIC@768503,4NX0C@976 NA|NA|NA MAG.T22.3_02436 1123057.P872_22425 7.4e-40 171.0 Cytophagia Bacteria 2DNB1@1,32WI2@2,47QY2@768503,4NR9G@976 NA|NA|NA MAG.T22.3_02437 1239962.C943_02386 6.6e-32 143.3 Cytophagia Bacteria 2BXZG@1,349K3@2,47VNJ@768503,4P6MR@976 NA|NA|NA MAG.T22.3_02438 1239962.C943_02387 4e-81 307.8 Cytophagia ko:K03088 ko00000,ko03021 Bacteria 47QFK@768503,4NR8R@976,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 MAG.T22.3_02439 1239962.C943_02389 3.7e-271 940.3 Cytophagia guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 Bacteria 47KQV@768503,4NDXQ@976,COG0516@1,COG0516@2,COG0517@1,COG0517@2 NA|NA|NA F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth MAG.T22.3_02441 1239962.C943_02390 3.7e-65 254.2 Bacteroidetes ko:K08983 ko00000 Bacteria 4NSFQ@976,COG3556@1,COG3556@2 NA|NA|NA S Predicted membrane protein (DUF2214) MAG.T22.3_02442 1239962.C943_02391 1.8e-72 278.9 Cytophagia ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 Bacteria 47PQ3@768503,4NM5B@976,COG0105@1,COG0105@2 NA|NA|NA F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate MAG.T22.3_02443 1239962.C943_02392 1.2e-196 692.2 Cytophagia nrnA GO:0008150,GO:0040007 2.7.7.72,3.1.13.3,3.1.3.7 ko:K00974,ko:K06881 ko00920,ko01100,ko01120,ko03013,map00920,map01100,map01120,map03013 R00188,R00508,R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03400 Bacteria 47JVC@768503,4NEXE@976,COG0618@1,COG0618@2 NA|NA|NA S phosphoesterase RecJ domain protein MAG.T22.3_02444 1239962.C943_02393 1.6e-158 565.5 Cytophagia Bacteria 47KIJ@768503,4NDW4@976,COG0545@1,COG0545@2 NA|NA|NA O Peptidyl-prolyl cis-trans isomerase MAG.T22.3_02445 1239962.C943_02394 4.3e-95 354.0 Cytophagia fkpA 5.2.1.8 ko:K03772,ko:K03773 ko00000,ko01000,ko03110 Bacteria 47RMV@768503,4NTM6@976,COG0545@1,COG0545@2 NA|NA|NA O Peptidyl-prolyl cis-trans isomerase MAG.T22.3_02446 1123057.P872_00780 5.8e-60 237.3 Cytophagia fkpA 5.2.1.8 ko:K03772,ko:K03773 ko00000,ko01000,ko03110 Bacteria 47UNG@768503,4P2JR@976,COG0545@1,COG0545@2 NA|NA|NA G Peptidyl-prolyl cis-trans isomerase MAG.T22.3_02447 1239962.C943_02396 1.2e-92 345.9 Cytophagia 2.1.1.334 ko:K21310 ko00920,map00920 R11546 RC02653 ko00000,ko00001,ko01000 Bacteria 47RFP@768503,4NTXI@976,COG2020@1,COG2020@2 NA|NA|NA O NnrU protein MAG.T22.3_02448 1239962.C943_02398 1.3e-224 785.4 Cytophagia sdh 1.5.1.7,1.5.1.8,1.5.1.9 ko:K00290,ko:K14157 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 M00030,M00032 R00715,R00716,R02313 RC00215,RC00217,RC00225,RC01532 ko00000,ko00001,ko00002,ko01000 Bacteria 47KRS@768503,4NF46@976,COG0686@1,COG0686@2 NA|NA|NA E Alanine dehydrogenase PNT, N-terminal domain MAG.T22.3_02449 1239962.C943_02399 1.1e-113 416.0 Cytophagia deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 ko:K01619 ko00030,map00030 R01066 RC00436,RC00437 ko00000,ko00001,ko01000 Bacteria 47NPE@768503,4NGE3@976,COG0274@1,COG0274@2 NA|NA|NA F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate MAG.T22.3_02450 1239962.C943_02400 3.5e-181 641.0 Cytophagia nptA ko:K14683 ko00000,ko02000,ko04147 2.A.58.1 Bacteria 47P5N@768503,4NHMY@976,COG1283@1,COG1283@2 NA|NA|NA P Na+/Pi-cotransporter MAG.T22.3_02451 1239962.C943_02401 3.9e-204 717.2 Cytophagia Bacteria 47P1S@768503,4NIVQ@976,COG0683@1,COG0683@2 NA|NA|NA E leucine binding MAG.T22.3_02452 1239962.C943_02402 2.5e-71 274.6 Cytophagia tadA GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.4.17.13,3.5.4.1,3.5.4.3,3.5.4.33,3.8.1.5,6.3.4.19 ko:K01297,ko:K01485,ko:K01487,ko:K01563,ko:K04075,ko:K11991 ko00230,ko00240,ko00330,ko00361,ko00625,ko01100,ko01120,map00230,map00240,map00330,map00361,map00625,map01100,map01120 R00974,R01411,R01676,R02922,R05284,R05367,R05368,R05369,R05370,R07669,R07670,R09597,R10223 RC00074,RC00204,RC00477,RC00514,RC00809,RC01317,RC01340,RC01341,RC02013,RC02633,RC02634 ko00000,ko00001,ko01000,ko01002,ko01011,ko03016 Bacteria 47PPY@768503,4NNJ2@976,COG0590@1,COG0590@2 NA|NA|NA FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) MAG.T22.3_02453 1239962.C943_02403 6.9e-118 429.9 Cytophagia sodA 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Bacteria 47JJV@768503,4NDZ4@976,COG0605@1,COG0605@2 NA|NA|NA P Destroys radicals which are normally produced within the cells and which are toxic to biological systems MAG.T22.3_02454 1239962.C943_02405 0.0 1554.7 Cytophagia Bacteria 47JAS@768503,4P4MW@976,COG1629@1,COG1629@2 NA|NA|NA P TonB-dependent receptor MAG.T22.3_02455 1239962.C943_02406 0.0 1154.0 Cytophagia Bacteria 29SIY@1,30DQ4@2,47N8T@768503,4NE5P@976 NA|NA|NA S Capsule assembly protein Wzi MAG.T22.3_02456 1239962.C943_02407 2.8e-125 454.5 Cytophagia Bacteria 47TKN@768503,4NQV2@976,COG3391@1,COG3391@2 NA|NA|NA S amine dehydrogenase activity MAG.T22.3_02457 1239962.C943_02408 8.9e-174 616.3 Cytophagia Bacteria 47MQM@768503,4NKC1@976,COG0156@1,COG0156@2 NA|NA|NA H aminotransferase class I and II MAG.T22.3_02458 1239962.C943_02409 1.1e-215 755.7 Cytophagia 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 47K31@768503,4NH6K@976,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase enzyme family MAG.T22.3_02459 1239962.C943_02410 2.9e-139 501.1 Cytophagia hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0388 Bacteria 47NT9@768503,4NK0E@976,COG0106@1,COG0106@2 NA|NA|NA E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase MAG.T22.3_02460 1239962.C943_02411 9.2e-184 649.4 Cytophagia Bacteria 47NCA@768503,4NGUK@976,COG4447@1,COG4447@2 NA|NA|NA S protein related to plant photosystem II stability assembly factor MAG.T22.3_02461 1239962.C943_02412 0.0 1088.6 Cytophagia msbA2 ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 47M5S@768503,4PKCT@976,COG1132@1,COG1132@2 NA|NA|NA V ABC-type multidrug transport system ATPase and permease MAG.T22.3_02463 1239962.C943_02415 0.0 1093.6 Cytophagia Bacteria 47M7Z@768503,4NF5T@976,COG2866@1,COG2866@2 NA|NA|NA E Zinc carboxypeptidase MAG.T22.3_02464 1239962.C943_02416 4.8e-164 583.9 Bacteroidetes htrB 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 4NQEF@976,COG1560@1,COG1560@2 NA|NA|NA M Bacterial lipid A biosynthesis acyltransferase MAG.T22.3_02465 1239962.C943_02417 3.7e-93 347.4 Cytophagia 5.2.1.8 ko:K03775 ko00000,ko01000,ko03110 Bacteria 47QER@768503,4NM29@976,COG1047@1,COG1047@2 NA|NA|NA O Peptidyl-prolyl cis-trans isomerase MAG.T22.3_02466 1239962.C943_02418 2.8e-97 361.3 Cytophagia Bacteria 47VDA@768503,4NMW6@976,COG1238@1,COG1238@2 NA|NA|NA I metal cluster binding MAG.T22.3_02467 1239962.C943_02419 0.0 1833.5 Cytophagia uvrA2 ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 47JVJ@768503,4NEHM@976,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate MAG.T22.3_02468 1239962.C943_02420 9.4e-56 222.6 Cytophagia Bacteria 47S59@768503,4NUV6@976,COG4634@1,COG4634@2 NA|NA|NA MAG.T22.3_02469 1239962.C943_02421 5.5e-39 166.4 Cytophagia Bacteria 47S0G@768503,4NV9U@976,COG2442@1,COG2442@2 NA|NA|NA S Protein of unknown function (DUF433) MAG.T22.3_02470 1239962.C943_02423 0.0 1469.5 Cytophagia atsD GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004065,GO:0004098,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0008484,GO:0009987,GO:0012505,GO:0016192,GO:0016787,GO:0016788,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042582,GO:0043167,GO:0043169,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0097708,GO:0099503,GO:1901135,GO:1901564,GO:1903509 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 47MT5@768503,4NEBN@976,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase MAG.T22.3_02471 1239962.C943_02424 2.8e-78 297.7 Cytophagia ko:K06991 ko00000 Bacteria 47PTX@768503,4NNHW@976,COG3565@1,COG3565@2 NA|NA|NA S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MAG.T22.3_02472 1239962.C943_02425 2.5e-164 584.7 Cytophagia rssA GO:0003674,GO:0003824,GO:0016787 ko:K07001 ko00000 Bacteria 47PF1@768503,4NDXY@976,COG1752@1,COG1752@2 NA|NA|NA M esterase of the alpha-beta hydrolase superfamily MAG.T22.3_02473 1239962.C943_02426 2e-109 401.7 Cytophagia Bacteria 47QDJ@768503,4NFUU@976,COG0500@1,COG0500@2 NA|NA|NA Q Tellurite resistance protein TehB MAG.T22.3_02475 1239962.C943_02428 7.2e-72 276.6 Cytophagia Bacteria 47RPY@768503,4NHRI@976,COG0454@1,COG0456@2 NA|NA|NA K PFAM Acetyltransferase (GNAT) family MAG.T22.3_02476 1239962.C943_02429 6e-76 290.0 Cytophagia SO4716 Bacteria 47RD6@768503,4NTGH@976,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family MAG.T22.3_02477 1239962.C943_02430 2.6e-117 427.9 Cytophagia queE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.97.1.4,4.3.99.3 ko:K04068,ko:K10026 ko00790,ko01100,map00790,map01100 R04710,R10002 RC02989 ko00000,ko00001,ko01000,ko03016 Bacteria 47MB1@768503,4NESC@976,COG0602@1,COG0602@2 NA|NA|NA H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds MAG.T22.3_02478 1239962.C943_02431 0.0 1245.0 Cytophagia Bacteria 47MTM@768503,4NE6G@976,COG0457@1,COG0457@2,COG2885@1,COG2885@2 NA|NA|NA MU Belongs to the ompA family MAG.T22.3_02479 1239962.C943_02432 0.0 1733.0 Bacteroidetes Bacteria 4P1Z5@976,COG1629@1,COG4771@2 NA|NA|NA P TonB-linked outer membrane protein, SusC RagA family MAG.T22.3_02480 1123057.P872_07970 5.5e-217 760.4 Cytophagia ko:K21572 ko00000,ko02000 8.A.46.1,8.A.46.3 Bacteria 47K1K@768503,4NGRH@976,COG3193@1,COG3193@2 NA|NA|NA S Pfam:SusD MAG.T22.3_02481 1239962.C943_02434 1e-60 239.6 Bacteroidetes Bacteria 2ECP6@1,336KZ@2,4NVKQ@976 NA|NA|NA MAG.T22.3_02482 1123057.P872_07980 2e-51 209.1 Cytophagia Bacteria 2A0BK@1,30NF3@2,47UVA@768503,4PAYZ@976 NA|NA|NA MAG.T22.3_02483 1239962.C943_02436 8.6e-80 302.8 Cytophagia 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 47PVC@768503,4NNY0@976,COG0720@1,COG0720@2 NA|NA|NA H TIGRFAM 6-pyruvoyl tetrahydropterin synthase QueD family protein MAG.T22.3_02484 1239962.C943_02438 0.0 1457.6 Cytophagia Bacteria 47JK5@768503,4NFQ6@976,COG2091@1,COG2091@2 NA|NA|NA H lysine biosynthetic process via aminoadipic acid MAG.T22.3_02485 1239962.C943_02439 6.3e-102 376.7 Cytophagia pdxH 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 Bacteria 47SMA@768503,4NP49@976,COG0259@1,COG0259@2 NA|NA|NA H Pyridoxamine 5'-phosphate oxidase MAG.T22.3_02486 746697.Aeqsu_0789 7.3e-26 122.9 Flavobacteriia ko:K06218 ko00000,ko02048 Bacteria 1I5T2@117743,4NVIF@976,COG2026@1,COG2026@2 NA|NA|NA DJ ParE toxin of type II toxin-antitoxin system, parDE MAG.T22.3_02487 1233951.IO90_02760 1.3e-12 78.6 Flavobacteriia Bacteria 1IB9A@117743,2BWKX@1,33G81@2,4NYKR@976 NA|NA|NA MAG.T22.3_02488 1239962.C943_02440 7.9e-70 269.6 Bacteroidetes 3.1.21.7 ko:K05982,ko:K07452 ko00000,ko01000,ko02048,ko03400 Bacteria 4NZHS@976,COG3695@1,COG3695@2 NA|NA|NA L enzyme binding MAG.T22.3_02489 1239962.C943_02441 1.5e-258 898.3 Cytophagia Bacteria 47NMR@768503,4NEVS@976,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T22.3_02490 1239962.C943_02442 8.9e-24 115.5 Bacteria Bacteria COG5450@1,COG5450@2 NA|NA|NA K positive regulation of growth MAG.T22.3_02491 1239962.C943_02443 1.6e-191 675.2 Bacteroidetes 3.6.4.12 ko:K03655,ko:K07506 ko03440,map03440 ko00000,ko00001,ko01000,ko03000,ko03400 Bacteria 4NHFY@976,COG1846@1,COG1846@2,COG3177@1,COG3177@2 NA|NA|NA K Fic/DOC family MAG.T22.3_02494 509635.N824_08490 5e-24 117.9 Sphingobacteriia yci Bacteria 1ITS4@117747,4NT3S@976,COG1525@1,COG1525@2 NA|NA|NA L Staphylococcal nuclease homologues MAG.T22.3_02495 484770.UFO1_1687 4.3e-46 191.4 Negativicutes Bacteria 1V7CC@1239,2AHFH@1,317ST@2,4H8E6@909932 NA|NA|NA S Domain of unknown function (DUF4145) MAG.T22.3_02496 1239962.C943_02448 2.5e-242 844.3 Cytophagia Bacteria 47JBI@768503,4NE10@976,COG1721@1,COG1721@2 NA|NA|NA S Protein of unknown function DUF58 MAG.T22.3_02497 1239962.C943_02449 1.5e-178 632.1 Cytophagia moxR2 ko:K03924 ko00000,ko01000 Bacteria 47KX2@768503,4NDVZ@976,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) MAG.T22.3_02498 1239962.C943_02450 2.4e-199 701.4 Cytophagia Bacteria 28IVH@1,2Z8TX@2,47N52@768503,4NEEW@976 NA|NA|NA MAG.T22.3_02499 1239962.C943_02451 3.7e-109 401.0 Cytophagia Bacteria 29GF6@1,303CZ@2,47PV1@768503,4NR6I@976 NA|NA|NA S Domain of unknown function (DUF4129) MAG.T22.3_02500 1239962.C943_02452 5.6e-131 473.8 Cytophagia flhB ko:K02401,ko:K13820 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2 Bacteria 47QAD@768503,4NMN3@976,COG1377@1,COG1377@2 NA|NA|NA NU Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin MAG.T22.3_02501 1239962.C943_02453 4e-176 624.0 Cytophagia ko:K06384 ko00000 Bacteria 47MPK@768503,4NG8D@976,COG1300@1,COG1300@2 NA|NA|NA S Stage II sporulation protein M MAG.T22.3_02502 1239962.C943_02454 1.1e-122 446.0 Cytophagia Bacteria 47P9X@768503,4NH7U@976,COG1714@1,COG1714@2 NA|NA|NA S RDD family MAG.T22.3_02503 1123277.KB893183_gene51 5.1e-31 140.2 Cytophagia ko:K19166 ko00000,ko01000,ko02048 Bacteria 47SBB@768503,4NVGW@976,COG4680@1,COG4680@2 NA|NA|NA S HigB_toxin, RelE-like toxic component of a toxin-antitoxin system MAG.T22.3_02504 1150600.ADIARSV_0589 3.6e-16 91.3 Sphingobacteriia ko:K18831 ko00000,ko02048,ko03000 Bacteria 1IXNN@117747,4NVQQ@976,COG5499@1,COG5499@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins MAG.T22.3_02506 1239962.C943_02457 3.1e-289 1000.3 Cytophagia ko:K21572 ko00000,ko02000 8.A.46.1,8.A.46.3 Bacteria 47YB3@768503,4PMHA@976,COG3637@1,COG3637@2 NA|NA|NA M Pfam:SusD MAG.T22.3_02507 1239962.C943_02458 0.0 1995.3 Cytophagia Bacteria 47Y6I@768503,4P1Z5@976,COG1629@1,COG4771@2 NA|NA|NA P TonB dependent receptor MAG.T22.3_02508 1239962.C943_02459 0.0 1959.9 Cytophagia Bacteria 47JJ5@768503,4NEE8@976,COG4888@1,COG4888@2 NA|NA|NA S ASPIC and UnbV MAG.T22.3_02509 1239962.C943_02460 5e-63 246.9 Cytophagia ko:K06996 ko00000 Bacteria 47X65@768503,4NSBC@976,COG3324@1,COG3324@2 NA|NA|NA E translation initiation factor activity MAG.T22.3_02510 1239962.C943_02461 9.8e-126 456.1 Bacteroidetes Bacteria 2DICZ@1,32UAY@2,4NU7D@976 NA|NA|NA MAG.T22.3_02511 1239962.C943_02462 1.2e-220 772.3 Cytophagia yagE Bacteria 47XGG@768503,4NICM@976,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease MAG.T22.3_02512 1239962.C943_02463 5.7e-189 666.8 Cytophagia gpsA GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 ko:K00057,ko:K07175 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 iJN678.gpsA,iJN746.PP_4169 Bacteria 47K3D@768503,4NF4R@976,COG0240@1,COG0240@2 NA|NA|NA I PFAM NAD-dependent glycerol-3-phosphate dehydrogenase MAG.T22.3_02513 1239962.C943_02464 0.0 1082.0 Cytophagia plsB 2.3.1.15 ko:K00631 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 47M20@768503,4NK5H@976,COG2937@1,COG2937@2 NA|NA|NA I Belongs to the GPAT DAPAT family MAG.T22.3_02514 1239962.C943_02465 1.6e-169 602.1 Cytophagia ispB GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 iYL1228.KPN_03597,ic_1306.c3945 Bacteria 47KFN@768503,4NET2@976,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family MAG.T22.3_02515 1239962.C943_02466 4e-243 847.0 Cytophagia trxC Bacteria 47JVX@768503,4PMB3@976,COG0526@1,COG0526@2 NA|NA|NA CO Redoxin MAG.T22.3_02516 1239962.C943_02468 9.9e-79 299.3 Cytophagia mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 ko:K03925 ko00000 Bacteria 47Q53@768503,4NM4X@976,COG2001@1,COG2001@2 NA|NA|NA K Belongs to the MraZ family MAG.T22.3_02517 1239962.C943_02469 4.6e-163 580.5 Cytophagia rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 47JJ6@768503,4NFQB@976,COG0275@1,COG0275@2 NA|NA|NA J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA MAG.T22.3_02518 1239962.C943_02470 8.8e-60 236.1 Cytophagia Bacteria 2ADW0@1,313N0@2,47R7E@768503,4NSUW@976 NA|NA|NA MAG.T22.3_02519 1239962.C943_02471 0.0 1358.6 Cytophagia ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 47K6U@768503,4NERV@976,COG0768@1,COG0768@2 NA|NA|NA M Cell division protein FtsI penicillin-binding protein 2 MAG.T22.3_02520 1239962.C943_02472 1.8e-273 948.0 Cytophagia murE 6.3.2.10,6.3.2.13 ko:K01928,ko:K15792 ko00300,ko00550,map00300,map00550 R02788,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 47JT3@768503,4NE9W@976,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan MAG.T22.3_02521 1239962.C943_02473 3.9e-218 763.8 Cytophagia mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 47KEP@768503,4NE0T@976,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan MAG.T22.3_02522 1239962.C943_02474 5.3e-240 836.6 Cytophagia murD 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 47KTX@768503,4NEFF@976,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) MAG.T22.3_02523 1239962.C943_02475 4.2e-209 733.8 Cytophagia ftsW ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 2.A.103.1 Bacteria 47K3R@768503,4NFIM@976,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family MAG.T22.3_02524 1239962.C943_02476 2.3e-196 691.4 Cytophagia murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 GT28 iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Bacteria 47JXF@768503,4NE6D@976,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) MAG.T22.3_02525 1239962.C943_02477 2.1e-260 904.4 Cytophagia murC 6.3.2.4,6.3.2.8 ko:K01921,ko:K01924 ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502 R01150,R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 47KY0@768503,4NE1V@976,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family MAG.T22.3_02526 1239962.C943_02478 1.5e-130 472.2 Cytophagia ftsQ ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Bacteria 47PU4@768503,4NGPN@976,COG1589@1,COG1589@2 NA|NA|NA M Cell division protein MAG.T22.3_02527 1239962.C943_02479 9.1e-245 852.4 Cytophagia ftsA GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Bacteria 47K6I@768503,4NE0V@976,COG0849@1,COG0849@2 NA|NA|NA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring MAG.T22.3_02529 1239962.C943_02480 9.4e-284 982.2 Cytophagia ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Bacteria 47MUN@768503,4NF8N@976,COG0206@1,COG0206@2 NA|NA|NA D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity MAG.T22.3_02530 1239962.C943_02481 1.7e-93 348.6 Cytophagia Bacteria 47PTV@768503,4NQV9@976,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase MAG.T22.3_02532 1239962.C943_02482 5.2e-99 367.1 Cytophagia punA 2.4.2.1 ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 47JII@768503,4NE4J@976,COG0005@1,COG0005@2 NA|NA|NA F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate MAG.T22.3_02533 1239962.C943_02483 7.8e-138 496.5 Bacteroidetes punA 2.4.2.1 ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 4NE4J@976,COG0005@1,COG0005@2 NA|NA|NA F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate MAG.T22.3_02534 1239962.C943_02485 4.3e-234 817.0 Cytophagia lys2 1.5.1.10,1.5.1.7 ko:K00290,ko:K00293 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 M00030,M00032 R00715,R02315 RC00215,RC00217,RC00225,RC01532 ko00000,ko00001,ko00002,ko01000 Bacteria 47MT4@768503,4NFM8@976,COG1748@1,COG1748@2 NA|NA|NA E Saccharopine dehydrogenase MAG.T22.3_02535 1239962.C943_02486 2.8e-79 301.2 Cytophagia cdd 2.4.2.2,3.5.4.5 ko:K00756,ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01570,R01876,R01878,R02296,R02484,R02485,R08221 RC00063,RC00074,RC00514 ko00000,ko00001,ko01000 Bacteria 47QAQ@768503,4NQED@976,COG0295@1,COG0295@2 NA|NA|NA F cytidine and deoxycytidylate deaminase MAG.T22.3_02536 1239962.C943_02487 1.6e-114 418.7 Cytophagia Bacteria 47QUH@768503,4NHWT@976,COG0400@1,COG0400@2 NA|NA|NA S PFAM phospholipase Carboxylesterase MAG.T22.3_02537 1239962.C943_02488 7.1e-77 293.1 Cytophagia Bacteria 2DMCZ@1,32N7D@2,47QYT@768503,4NS5N@976 NA|NA|NA S Uncharacterised protein family (UPF0158) MAG.T22.3_02538 1239962.C943_02489 5e-235 820.1 Cytophagia natB ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 47JCK@768503,4NFSZ@976,COG1668@1,COG1668@2 NA|NA|NA CP COGs COG1668 ABC-type Na efflux pump permease component MAG.T22.3_02539 1239962.C943_02490 2.1e-147 528.5 Cytophagia natA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 47KYF@768503,4NEJE@976,COG4152@1,COG4152@2 NA|NA|NA S PFAM ABC transporter MAG.T22.3_02540 1239962.C943_02491 3.8e-125 454.5 Cytophagia Bacteria 2BK1P@1,32EEX@2,47QMH@768503,4NRXN@976 NA|NA|NA MAG.T22.3_02541 1239962.C943_02493 2.8e-162 578.2 Cytophagia dnaJ GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 ko:K03686 ko00000,ko03029,ko03110 Bacteria 47MD9@768503,4NF41@976,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins MAG.T22.3_02542 1239962.C943_02494 2e-87 328.6 Cytophagia grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 ko:K02652,ko:K03687 ko00000,ko02035,ko02044,ko03029,ko03110 3.A.15.2 Bacteria 47QCT@768503,4NQ6M@976,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ MAG.T22.3_02543 1239962.C943_02496 3.1e-181 641.0 Cytophagia obg GO:0000003,GO:0000160,GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007059,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019538,GO:0019954,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0034622,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0040007,GO:0042254,GO:0042255,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0043933,GO:0043934,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1990904 ko:K03979 ko00000,ko01000,ko03009 Bacteria 47JCS@768503,4NEK4@976,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control MAG.T22.3_02544 1239962.C943_02497 2.7e-100 371.3 Cytophagia adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47NHN@768503,4NG7J@976,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism MAG.T22.3_02545 1239962.C943_02498 8.7e-81 306.2 Cytophagia hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,2.7.4.3,6.3.4.19 ko:K00760,ko:K00939,ko:K15780 ko00230,ko00730,ko00983,ko01100,ko01110,ko01130,map00230,map00730,map00983,map01100,map01110,map01130 M00049 R00127,R00190,R01132,R01229,R01547,R02142,R08237,R08238,R08245,R11319 RC00002,RC00063,RC00122 ko00000,ko00001,ko00002,ko01000,ko03016,ko04147 iHN637.CLJU_RS16720 Bacteria 47PQ9@768503,4NNIB@976,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family MAG.T22.3_02546 1239962.C943_02499 1.3e-152 545.8 Cytophagia celM 3.4.11.7 ko:K01261 ko00000,ko01000,ko01002 Bacteria 47MR1@768503,4NH34@976,COG1363@1,COG1363@2 NA|NA|NA G PFAM M42 glutamyl aminopeptidase MAG.T22.3_02547 1239962.C943_02500 1.2e-228 798.9 Cytophagia ompA ko:K03286 ko00000,ko02000 1.B.6 Bacteria 47P03@768503,4NHTP@976,COG2885@1,COG2885@2 NA|NA|NA M Belongs to the ompA family MAG.T22.3_02548 1239962.C943_02501 7e-113 413.3 Cytophagia upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000 iSB619.SA_RS11010 Bacteria 47P6X@768503,4NFZM@976,COG0035@1,COG0035@2 NA|NA|NA F uracil phosphoribosyltransferase MAG.T22.3_02549 1239962.C943_02502 9.5e-140 503.1 Cytophagia yrbG ko:K07301 ko00000,ko02000 2.A.19.5 Bacteria 47PMC@768503,4NFBC@976,COG0530@1,COG0530@2 NA|NA|NA P K -dependent Na Ca exchanger MAG.T22.3_02550 1239962.C943_02503 1.2e-64 252.7 Cytophagia Bacteria 2E5FG@1,33075@2,47QE3@768503,4NWB7@976 NA|NA|NA MAG.T22.3_02551 1239962.C943_02504 2.7e-155 554.7 Cytophagia sdaA GO:0003674,GO:0003824,GO:0003941,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006563,GO:0006565,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016020,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 iECSP_1301.ECSP_4084,iECUMN_1333.ECUMN_2106,iJN746.PP_3144 Bacteria 47JRY@768503,4NENR@976,COG1760@1,COG1760@2 NA|NA|NA E PFAM Serine dehydratase alpha chain MAG.T22.3_02552 1239962.C943_02505 1e-157 562.8 Cytophagia 5.2.1.8 ko:K01802,ko:K03772,ko:K03773 ko00000,ko01000,ko03110 Bacteria 47P8J@768503,4NMX8@976,COG0545@1,COG0545@2 NA|NA|NA O Peptidylprolyl isomerase MAG.T22.3_02553 1239962.C943_02506 6e-196 690.3 Cytophagia Bacteria 2E3A1@1,32Y9I@2,47P5Z@768503,4NWKC@976 NA|NA|NA MAG.T22.3_02554 1239962.C943_02507 1.7e-99 368.6 Cytophagia ko:K03088 ko00000,ko03021 Bacteria 47P68@768503,4NKHT@976,COG1595@1,COG1595@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family MAG.T22.3_02555 1239962.C943_02508 5.8e-132 476.9 Cytophagia Bacteria 28MPU@1,2ZAYW@2,47NJK@768503,4NRQD@976 NA|NA|NA MAG.T22.3_02556 1239962.C943_02509 3e-167 594.3 Cytophagia lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 R07767,R07768 RC01978 ko00000,ko00001,ko01000 Bacteria 47JGZ@768503,4NEB5@976,COG0320@1,COG0320@2 NA|NA|NA H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives MAG.T22.3_02557 1239962.C943_02511 2.1e-230 804.7 Cytophagia vicK 2.1.1.80,2.7.13.3,3.1.1.61 ko:K07709,ko:K13924 ko02020,ko02030,map02020,map02030 M00499,M00506 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Bacteria 47Y3V@768503,4NEMP@976,COG4191@1,COG4191@2 NA|NA|NA T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MAG.T22.3_02558 1239962.C943_02512 2.4e-308 1063.9 Cytophagia prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02837,ko:K07133 ko00000,ko03012 Bacteria 47JQE@768503,4NFEZ@976,COG4108@1,COG4108@2 NA|NA|NA J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP MAG.T22.3_02559 1239962.C943_02513 2.4e-138 498.0 Cytophagia rluC 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 Bacteria 47KV5@768503,4NFS8@976,COG0564@1,COG0564@2 NA|NA|NA J Pseudouridine synthase MAG.T22.3_02560 1239962.C943_02516 8.1e-69 266.5 Cytophagia pgm3 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 47S0K@768503,4NQWA@976,COG0406@1,COG0406@2 NA|NA|NA G Histidine phosphatase superfamily (branch 1) MAG.T22.3_02561 1239962.C943_02518 9.7e-278 962.2 Cytophagia glpD GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 R00848 RC00029 ko00000,ko00001,ko01000 Bacteria 47MN6@768503,4NEYG@976,COG0578@1,COG0578@2 NA|NA|NA C PFAM FAD dependent oxidoreductase MAG.T22.3_02562 1239962.C943_02519 3.5e-283 980.3 Cytophagia glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 Bacteria 47KFD@768503,4NFUH@976,COG0554@1,COG0554@2 NA|NA|NA C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate MAG.T22.3_02563 1239962.C943_02520 8.6e-128 463.0 Cytophagia glpF ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 Bacteria 47KUR@768503,4NEFK@976,COG0580@1,COG0580@2 NA|NA|NA G Belongs to the MIP aquaporin (TC 1.A.8) family MAG.T22.3_02564 1239962.C943_02521 4.5e-208 730.3 Cytophagia yngJ GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 ko:K00248,ko:K11410,ko:K18244 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 Bacteria 47K4J@768503,4NEHA@976,COG1960@1,COG1960@2 NA|NA|NA I acyl-CoA dehydrogenase MAG.T22.3_02565 1239962.C943_02523 1.4e-273 948.3 Cytophagia htrA 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 47KF5@768503,4NFCS@976,COG0265@1,COG0265@2 NA|NA|NA O PDZ domain (Also known as DHR or GLGF) MAG.T22.3_02566 1239962.C943_02524 3.2e-68 264.6 Cytophagia ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 47R4W@768503,4NSJB@976,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family MAG.T22.3_02567 1239962.C943_02525 0.0 1396.7 Cytophagia mscM ko:K05802 ko00000,ko02000 1.A.23.1.1 Bacteria 47KYP@768503,4NEAM@976,COG3264@1,COG3264@2 NA|NA|NA M Mechanosensitive ion channel MAG.T22.3_02568 1239962.C943_02526 7e-303 1045.8 Cytophagia ko:K06158 ko00000,ko03012 Bacteria 47JG7@768503,4NG1W@976,COG0488@1,COG0488@2 NA|NA|NA S COGs COG0488 ATPase components of ABC transporter with duplicated ATPase domains MAG.T22.3_02569 1239962.C943_02529 1.6e-304 1052.0 Cytophagia Bacteria 47NMF@768503,4NESU@976,COG4447@1,COG4447@2 NA|NA|NA G Sortilin, neurotensin receptor 3, MAG.T22.3_02571 643648.Slip_2012 4.7e-07 60.5 Clostridia ko:K05788 ko00000,ko03032,ko03036,ko03400 Bacteria 1UJ3U@1239,24P9B@186801,COG0776@1,COG0776@2 NA|NA|NA L Protein of unknown function (DUF2442) MAG.T22.3_02572 1189612.A33Q_3850 3.6e-36 157.1 Cytophagia Bacteria 2E3EN@1,32YDN@2,47WP2@768503,4PNB3@976 NA|NA|NA S Domain of unknown function (DUF4160) MAG.T22.3_02573 1239962.C943_02530 9e-156 556.2 Cytophagia sucD GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009361,GO:0009987,GO:0016310,GO:0019538,GO:0032991,GO:0036211,GO:0040011,GO:0042709,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0046777,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071973,GO:0097588,GO:1901564,GO:1902494 6.2.1.5 ko:K01902,ko:K02381 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_0608 Bacteria 47K03@768503,4NE6B@976,COG0074@1,COG0074@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit MAG.T22.3_02574 1239962.C943_02531 0.0 2051.2 Cytophagia ko:K16923 M00582 ko00000,ko00002,ko02000 3.A.1.28 Bacteria 47NDW@768503,4NGX0@976,COG3292@1,COG3292@2,COG5002@1,COG5002@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain MAG.T22.3_02575 1239962.C943_02532 1e-210 739.2 Cytophagia Bacteria 47JUV@768503,4NG0Y@976,COG0642@1,COG0745@1,COG0745@2,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T22.3_02576 1239962.C943_02533 3.6e-106 391.0 Cytophagia ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 47MDH@768503,4NNS2@976,COG1136@1,COG1136@2 NA|NA|NA V ABC-type antimicrobial peptide transport system, ATPase component MAG.T22.3_02577 1239962.C943_02534 5.7e-217 760.0 Cytophagia ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 47KE0@768503,4NF60@976,COG0577@1,COG0577@2 NA|NA|NA V ABC-type transport system involved in lipoprotein release permease component MAG.T22.3_02578 1239962.C943_02535 7.2e-74 283.1 Cytophagia ko:K09950 ko00000 Bacteria 47RTG@768503,4NTUM@976,COG3495@1,COG3495@2 NA|NA|NA S Protein conserved in bacteria MAG.T22.3_02579 1239962.C943_02536 1e-153 549.3 Cytophagia dat 2.6.1.21,2.6.1.42 ko:K00824,ko:K00826 ko00270,ko00280,ko00290,ko00310,ko00330,ko00360,ko00472,ko00473,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00310,map00330,map00360,map00472,map00473,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01148,R01214,R01582,R02199,R02459,R02851,R02924,R05053,R10991 RC00006,RC00008,RC00025,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 47M6P@768503,4PJ29@976,COG0115@1,COG0115@2 NA|NA|NA EH Pfam Aminotransferase class IV MAG.T22.3_02580 1123057.P872_03970 1.4e-29 136.0 Cytophagia Bacteria 2EF8J@1,32MJU@2,47QPB@768503,4NQFP@976 NA|NA|NA S MerC mercury resistance protein MAG.T22.3_02581 1123057.P872_03975 4.9e-25 120.9 Cytophagia Bacteria 2EG8H@1,33A0B@2,47SNZ@768503,4NY1M@976 NA|NA|NA MAG.T22.3_02582 1239962.C943_02538 4.7e-73 280.4 Cytophagia aniA Bacteria 47REP@768503,4NTWV@976,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c, class I MAG.T22.3_02583 1239962.C943_02539 1.7e-122 445.3 Cytophagia ypmQ ko:K07152,ko:K08976 ko00000,ko03029 Bacteria 47NK1@768503,4NFH2@976,COG1999@1,COG1999@2 NA|NA|NA S protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems MAG.T22.3_02584 1239962.C943_02540 7.1e-95 353.2 Cytophagia ko:K08973 ko00000 Bacteria 47PXS@768503,4NEWG@976,COG1981@1,COG1981@2 NA|NA|NA S PFAM Uncharacterised protein family (UPF0093) MAG.T22.3_02585 1239962.C943_02541 1.6e-70 271.9 Cytophagia Bacteria 2CHKN@1,32S67@2,47RJ3@768503,4NSJV@976 NA|NA|NA MAG.T22.3_02586 1239962.C943_02542 1.7e-165 588.6 Cytophagia argK GO:0003674,GO:0003824,GO:0003924,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 ko:K07588 ko00000,ko01000 Bacteria 47M9T@768503,4NE7Y@976,COG1703@1,COG1703@2 NA|NA|NA E TIGRFAM LAO AO transport system ATPase MAG.T22.3_02587 1239962.C943_02543 6.3e-121 440.3 Cytophagia Bacteria 28JBH@1,2Z967@2,47PBF@768503,4NNHF@976 NA|NA|NA S Protein of unknown function (DUF3298) MAG.T22.3_02588 1239962.C943_02544 2.6e-269 934.1 Cytophagia dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 47KR6@768503,4NE6Q@976,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids MAG.T22.3_02589 1239962.C943_02545 1.7e-225 788.5 Cytophagia mutA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016999,GO:0017144,GO:0019541,GO:0019678,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046459,GO:0071704,GO:0071944 5.4.99.2,5.4.99.63 ko:K01847,ko:K14447 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833,R09292 RC00395,RC02835 ko00000,ko00001,ko00002,ko01000 Bacteria 47JP5@768503,4NDVE@976,COG1884@1,COG1884@2 NA|NA|NA I Methylmalonyl-CoA mutase N-terminal domain subunit MAG.T22.3_02590 1239962.C943_02546 0.0 1315.8 Cytophagia mutB 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 Bacteria 47JW5@768503,4NFS0@976,COG1884@1,COG1884@2,COG2185@1,COG2185@2 NA|NA|NA I Methylmalonyl-CoA mutase MAG.T22.3_02591 1239962.C943_02547 0.0 1340.1 Cytophagia ybaL_1 Bacteria 47KD1@768503,4NF11@976,COG0475@1,COG0475@2 NA|NA|NA P Sodium/hydrogen exchanger family MAG.T22.3_02592 1239962.C943_02548 1.1e-66 259.2 Bacteroidetes 3.5.1.9 ko:K01432 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 Bacteria 4NUK2@976,COG0657@1,COG0657@2 NA|NA|NA I acetylesterase activity MAG.T22.3_02593 1239962.C943_02549 3.1e-53 214.2 Cytophagia 1.17.1.1 ko:K00523,ko:K04755 ko00520,map00520 R03391,R03392 RC00230 ko00000,ko00001,ko01000 Bacteria 47QBT@768503,4NQ4P@976,COG0633@1,COG0633@2 NA|NA|NA C Ferredoxin MAG.T22.3_02594 1239962.C943_02550 4.4e-191 673.7 Cytophagia trxB2 1.18.1.2,1.19.1.1,1.8.1.9 ko:K00384,ko:K21567 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 Bacteria 47KZW@768503,4NEQM@976,COG0492@1,COG0492@2 NA|NA|NA C Ferredoxin--NADP reductase MAG.T22.3_02595 1239962.C943_02551 3.6e-73 280.8 Cytophagia marR7 Bacteria 47PSY@768503,4NP8N@976,COG1846@1,COG1846@2 NA|NA|NA K transcriptional regulator MAG.T22.3_02596 1239962.C943_02552 4.8e-162 577.0 Cytophagia Bacteria 47NFY@768503,4NK1X@976,COG2849@1,COG2849@2 NA|NA|NA S repeat protein MAG.T22.3_02597 1239962.C943_02553 1.4e-223 781.9 Cytophagia aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 iHN637.CLJU_RS06550 Bacteria 47JJH@768503,4NENS@976,COG0436@1,COG0436@2 NA|NA|NA E PFAM Aminotransferase class I and II MAG.T22.3_02598 1239962.C943_02554 1.8e-165 588.6 Bacteroidetes yhjY ko:K12287,ko:K12686 ko00000,ko02000,ko02044 1.B.12.8 Bacteria 4NMBF@976,COG5571@1,COG5571@2 NA|NA|NA N Psort location OuterMembrane, score MAG.T22.3_02599 1239962.C943_02555 3.2e-289 1000.3 Cytophagia pcd GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 47JJR@768503,4NFPJ@976,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family MAG.T22.3_02602 1189612.A33Q_3998 8.6e-138 497.3 Cytophagia Bacteria 2E3YY@1,32YVW@2,47W4W@768503,4NX9K@976 NA|NA|NA MAG.T22.3_02605 1239962.C943_02691 0.0 1230.3 Cytophagia ko:K02014 ko00000,ko02000 1.B.14 Bacteria 47P5E@768503,4NHH8@976,COG4206@1,COG4206@2 NA|NA|NA H TonB dependent receptor MAG.T22.3_02606 1239962.C943_02694 0.0 1336.6 Cytophagia Bacteria 47K4C@768503,4NE13@976,COG0308@1,COG0308@2 NA|NA|NA E Peptidase family M1 domain MAG.T22.3_02607 1239962.C943_02695 2.5e-195 688.0 Cytophagia MA20_15840 Bacteria 47K9P@768503,4NFZJ@976,COG5434@1,COG5434@2 NA|NA|NA M Belongs to the glycosyl hydrolase 28 family MAG.T22.3_02608 1239962.C943_02696 7.7e-223 779.6 Cytophagia MA20_15840 Bacteria 47KM6@768503,4NE9Y@976,COG5434@1,COG5434@2 NA|NA|NA M Periplasmic copper-binding protein (NosD) MAG.T22.3_02609 1239962.C943_02697 1.8e-69 268.9 Cytophagia Bacteria 47RBF@768503,4NSMK@976,COG0664@1,COG0664@2 NA|NA|NA T Cyclic nucleotide-monophosphate binding domain MAG.T22.3_02610 1239962.C943_02698 4.9e-105 387.1 Cytophagia ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 47PA6@768503,4NDV6@976,COG0817@1,COG0817@2 NA|NA|NA L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group MAG.T22.3_02611 1239962.C943_02699 8.2e-154 550.1 Cytophagia Bacteria 47KYN@768503,4NG9C@976,COG1215@1,COG1215@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T22.3_02612 1239962.C943_02700 2.7e-39 167.5 Cytophagia Bacteria 2EK8F@1,33DYT@2,47SMI@768503,4NY32@976 NA|NA|NA MAG.T22.3_02613 1239962.C943_02701 1.9e-220 771.5 Cytophagia rsbU 3.1.3.3,4.6.1.1 ko:K01768,ko:K07315 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko03021 Bacteria 47KA0@768503,4NI98@976,COG2208@1,COG2208@2 NA|NA|NA KT PFAM Stage II sporulation protein E (SpoIIE) MAG.T22.3_02614 1239962.C943_02702 9.9e-85 319.3 Cytophagia pgdA_1 Bacteria 47PE1@768503,4NM7D@976,COG0726@1,COG0726@2 NA|NA|NA G PFAM Polysaccharide deacetylase MAG.T22.3_02615 1239962.C943_02703 9.8e-200 702.6 Cytophagia Bacteria 47JFA@768503,4NKDX@976,COG1215@1,COG1215@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T22.3_02616 1239962.C943_02704 1.6e-140 505.4 Cytophagia tatD ko:K03424 ko00000,ko01000 Bacteria 47KE3@768503,4NEVW@976,COG0084@1,COG0084@2 NA|NA|NA L TIGRFAM hydrolase, TatD family MAG.T22.3_02617 1239962.C943_02705 1.1e-197 695.7 Cytophagia ansA 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 R00485 RC00010,RC02798 ko00000,ko00001,ko01000 Bacteria 47KWG@768503,4NE2Z@976,COG0252@1,COG0252@2 NA|NA|NA EJ TIGRFAM L-asparaginases, type I MAG.T22.3_02619 1121904.ARBP01000008_gene3254 5.2e-223 780.4 Cytophagia Bacteria 47KWC@768503,4NFC9@976,COG3119@1,COG3119@2 NA|NA|NA P Domain of unknown function MAG.T22.3_02620 866536.Belba_1907 3.7e-116 424.5 Cytophagia exbB ko:K03561 ko00000,ko02000 1.A.30.2.1 Bacteria 47JQQ@768503,4NEA2@976,COG0811@1,COG0811@2 NA|NA|NA U PFAM MotA TolQ ExbB proton channel family MAG.T22.3_02621 1189612.A33Q_2123 7.5e-31 139.8 Cytophagia Bacteria 2DDI9@1,2ZI7K@2,47WMJ@768503,4P7HD@976 NA|NA|NA MAG.T22.3_02622 1189612.A33Q_2122 6.4e-95 353.6 Cytophagia ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 47JBU@768503,4NHYQ@976,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein ExbD/TolR MAG.T22.3_02623 1189612.A33Q_2121 1.2e-69 269.2 Cytophagia ko:K03559 ko00000,ko02000 1.A.30.2.1 Bacteria 47PP4@768503,4NKT1@976,COG0848@1,COG0848@2 NA|NA|NA U Biopolymer transport protein ExbD/TolR MAG.T22.3_02624 1239962.C943_02712 3e-224 784.3 Cytophagia yxiO ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 Bacteria 47JQM@768503,4NEKI@976,COG2270@1,COG2270@2 NA|NA|NA S PFAM Vacuole effluxer Atg22 like MAG.T22.3_02625 1239962.C943_02713 2.4e-225 788.1 Cytophagia nnrD 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 47JYX@768503,4NG2F@976,COG0062@1,COG0062@2,COG0063@1,COG0063@2 NA|NA|NA G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration MAG.T22.3_02626 1239962.C943_02714 7.1e-223 779.6 Cytophagia sotB Bacteria 47JIH@768503,4NESW@976,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T22.3_02627 1239962.C943_02715 4.6e-274 949.9 Cytophagia asnS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iSDY_1059.SDY_2327 Bacteria 47JG8@768503,4NDY4@976,COG0017@1,COG0017@2 NA|NA|NA J Asparaginyl-tRNA synthetase MAG.T22.3_02628 1239962.C943_02716 8e-250 869.4 Cytophagia rpoN ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Bacteria 47KC2@768503,4NE5B@976,COG1508@1,COG1508@2 NA|NA|NA K RNA polymerase, sigma-54 factor MAG.T22.3_02629 1239962.C943_02717 6.2e-95 353.6 Cytophagia ko:K12977 ko00000,ko01000,ko01005 Bacteria 47PT7@768503,4NUPJ@976,COG0671@1,COG0671@2 NA|NA|NA I phosphoesterase, PA-phosphatase related MAG.T22.3_02630 1239962.C943_02718 3.4e-140 504.2 Cytophagia Bacteria 2A7CX@1,30W9X@2,47RRQ@768503,4P9P3@976 NA|NA|NA S Outer membrane protein beta-barrel domain MAG.T22.3_02634 1239962.C943_01047 9.9e-180 636.0 Cytophagia Bacteria 47KE6@768503,4NEVD@976,COG3064@1,COG3064@2 NA|NA|NA M TIGRFAM Bacteroidetes-specific MAG.T22.3_02635 1239962.C943_01048 1.2e-277 961.8 Cytophagia Bacteria 47NK2@768503,4NEHY@976,COG2234@1,COG2234@2 NA|NA|NA S Peptidase, M28 MAG.T22.3_02636 1239962.C943_01049 4e-50 203.8 Cytophagia Bacteria 47RAG@768503,4NVM6@976,COG0607@1,COG0607@2 NA|NA|NA P PFAM Rhodanese-like domain MAG.T22.3_02637 1239962.C943_01050 0.0 1190.3 Cytophagia Bacteria 28M1N@1,2ZAGE@2,47JC7@768503,4NIDD@976 NA|NA|NA MAG.T22.3_02638 1239962.C943_01051 1.2e-137 495.7 Cytophagia 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 47KQI@768503,4NSUI@976,COG2815@1,COG2815@2 NA|NA|NA S PFAM PASTA domain MAG.T22.3_02639 1239962.C943_01052 6.8e-150 536.6 Cytophagia dnaQ 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 47N5P@768503,4NE82@976,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III MAG.T22.3_02640 1239962.C943_01053 1.7e-257 894.8 Cytophagia murC 6.3.2.4,6.3.2.45,6.3.2.8 ko:K01921,ko:K01924,ko:K02558 ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502 R01150,R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 47JEX@768503,4NF99@976,COG0773@1,COG0773@2 NA|NA|NA M Mur ligase middle domain MAG.T22.3_02641 1239962.C943_01055 3.9e-290 1003.4 Cytophagia dnaB 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 47JB5@768503,4NF8P@976,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication MAG.T22.3_02642 1239962.C943_01056 1.9e-170 605.1 Cytophagia Bacteria 47KMW@768503,4NGIY@976,COG0604@1,COG0604@2 NA|NA|NA C alcohol dehydrogenase MAG.T22.3_02643 1239962.C943_01057 7.5e-41 172.9 Bacteria pilF ko:K02656 ko00000,ko02035,ko02044 Bacteria COG3063@1,COG3063@2 NA|NA|NA NU photosynthesis MAG.T22.3_02644 1239962.C943_01058 6e-129 466.8 Cytophagia etfB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 ko:K03521 ko00000 Bacteria 47KZ2@768503,4NFWB@976,COG2086@1,COG2086@2 NA|NA|NA C Electron transfer flavoprotein MAG.T22.3_02645 1239962.C943_01059 4.6e-161 573.9 Cytophagia etfA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 ko:K03522 ko00000,ko04147 Bacteria 47JUQ@768503,4NFSE@976,COG2025@1,COG2025@2 NA|NA|NA C Electron transfer flavoprotein, alpha subunit MAG.T22.3_02646 1239962.C943_01060 3.9e-102 377.5 Cytophagia yqdE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K03617,ko:K08999 ko00000 Bacteria 47KJI@768503,4NGSW@976,COG1259@1,COG1259@2,COG3880@1,COG3880@2 NA|NA|NA L PFAM Uncharacterised ACR, COG1259 MAG.T22.3_02647 1239962.C943_01061 1.9e-226 791.6 Cytophagia yeiM ko:K03317 ko00000 2.A.41 Bacteria 47KKZ@768503,4NEYN@976,COG1972@1,COG1972@2 NA|NA|NA F PFAM Na dependent nucleoside transporter MAG.T22.3_02648 1239962.C943_01062 2e-79 301.6 Cytophagia ppiB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria 47P72@768503,4NKQ7@976,COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides MAG.T22.3_02649 1239962.C943_01063 3.5e-307 1060.1 Cytophagia pckA GO:0000166,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS09060,iYO844.BSU30560 Bacteria 47JC3@768503,4NEGI@976,COG1866@1,COG1866@2 NA|NA|NA H Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA MAG.T22.3_02650 1239962.C943_01065 1.7e-293 1014.6 Cytophagia dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03305 ko00000 2.A.17 Bacteria 47JX4@768503,4NE8R@976,COG3104@1,COG3104@2 NA|NA|NA E TIGRFAM amino acid peptide transporter (Peptide H symporter), bacterial MAG.T22.3_02652 1239962.C943_01068 1.3e-71 275.8 Cytophagia Bacteria 2B1RZ@1,31U7Q@2,47Q5B@768503,4NR0B@976 NA|NA|NA MAG.T22.3_02653 1239962.C943_01069 6e-61 240.0 Cytophagia Bacteria 47Q8V@768503,4PKNW@976,COG0745@1,COG0745@2 NA|NA|NA KT response regulator MAG.T22.3_02654 1239962.C943_01070 7.3e-52 209.5 Cytophagia Bacteria 47R9Z@768503,4NSJX@976,COG4323@1,COG4323@2 NA|NA|NA S Protein of unknown function (DUF962) MAG.T22.3_02655 866536.Belba_2461 3.9e-46 191.4 Cytophagia Bacteria 2BGT2@1,32ASI@2,47UKZ@768503,4PAVM@976 NA|NA|NA S Domain of unknown function (DUF4136) MAG.T22.3_02656 1239962.C943_01072 1.2e-166 592.4 Cytophagia ydiY ko:K07283 ko00000 Bacteria 47NWC@768503,4NGB2@976,COG3137@1,COG3137@2 NA|NA|NA M Protein of unknown function (DUF3078) MAG.T22.3_02657 1239962.C943_01073 2.8e-130 471.5 Bacteroidetes uspF Bacteria 4NFZ5@976,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein MAG.T22.3_02659 1239962.C943_01074 1e-221 775.8 Cytophagia sucC 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 47JZU@768503,4NFHA@976,COG0045@1,COG0045@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit MAG.T22.3_02660 1239962.C943_01075 2.2e-114 418.3 Cytophagia lolD ko:K09810 ko02010,map02010 M00255 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 Bacteria 47JS7@768503,4NGDU@976,COG1136@1,COG1136@2 NA|NA|NA V Part of the ABC transporter complex LolCDE involved in the translocation of MAG.T22.3_02661 1239962.C943_01076 2.4e-131 474.9 Cytophagia ko:K15270 ko00000,ko02000 2.A.7.3.7 Bacteria 47KBM@768503,4NDYH@976,COG0697@1,COG0697@2 NA|NA|NA EG PFAM EamA-like transporter family MAG.T22.3_02662 1239962.C943_01077 1.7e-130 472.2 Cytophagia Bacteria 2B99M@1,322KZ@2,47QJC@768503,4NS5P@976 NA|NA|NA MAG.T22.3_02663 1239962.C943_01078 7.6e-20 103.2 Cytophagia Bacteria 47JQ1@768503,4NHCZ@976,COG0457@1,COG0457@2,COG4995@1,COG4995@2 NA|NA|NA S CHAT domain MAG.T22.3_02664 1239962.C943_02361 1.2e-191 675.6 Cytophagia ydgJ 1.1.1.371 ko:K16044 ko00562,ko01120,map00562,map01120 R09954 RC00182 ko00000,ko00001,ko01000 Bacteria 47KWZ@768503,4NEQB@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.3_02665 1239962.C943_02360 4.6e-106 390.6 Cytophagia Bacteria 47QR7@768503,4NSGV@976,COG2197@1,COG2197@2 NA|NA|NA K PFAM response regulator receiver MAG.T22.3_02666 1239962.C943_02359 4.3e-122 444.1 Cytophagia Bacteria 47R04@768503,4NM9X@976,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase MAG.T22.3_02667 1123057.P872_01855 3.1e-31 142.1 Cytophagia Bacteria 2AT2A@1,31II8@2,47VMC@768503,4PK70@976 NA|NA|NA MAG.T22.3_02668 1239962.C943_02356 2.1e-59 235.0 Cytophagia Bacteria 2DWBR@1,33ZHZ@2,47VCS@768503,4P4I5@976 NA|NA|NA MAG.T22.3_02669 866536.Belba_0635 3e-42 178.7 Cytophagia Bacteria 2DVC3@1,33V7P@2,47UM9@768503,4P2C0@976 NA|NA|NA MAG.T22.3_02670 1239962.C943_02354 0.0 1813.1 Cytophagia secF GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03072,ko:K03074,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 Bacteria 47JV4@768503,4NE1X@976,COG0341@1,COG0341@2,COG0342@1,COG0342@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA MAG.T22.3_02671 1239962.C943_02353 1.8e-45 188.3 Cytophagia Bacteria 2DXEV@1,344Q9@2,47VXT@768503,4P5E9@976 NA|NA|NA MAG.T22.3_02672 1239962.C943_02352 5e-116 423.7 Cytophagia udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 iSBO_1134.SBO_0893 Bacteria 47P8Z@768503,4NEEC@976,COG0572@1,COG0572@2 NA|NA|NA F Belongs to the uridine kinase family MAG.T22.3_02673 1239962.C943_02351 2.2e-99 368.2 Cytophagia rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 47PE9@768503,4NM42@976,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions MAG.T22.3_02674 1239962.C943_02350 1.1e-101 375.9 Cytophagia yvdD_1 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 47Q15@768503,4NGWU@976,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family MAG.T22.3_02675 1239962.C943_02348 2.1e-82 311.6 Cytophagia msrC 1.8.4.14 ko:K08968 ko00270,map00270 R02025 RC00639 ko00000,ko00001,ko01000 Bacteria 47PCM@768503,4NM6D@976,COG1956@1,COG1956@2 NA|NA|NA T GAF domain-containing protein MAG.T22.3_02676 1239962.C943_02347 1.1e-179 636.0 Cytophagia ribD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 ko:K00082,ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1624,iLJ478.TM1828 Bacteria 47KBG@768503,4NFJE@976,COG0117@1,COG0117@2,COG1985@1,COG1985@2 NA|NA|NA H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate MAG.T22.3_02677 1239962.C943_02346 3.9e-126 457.6 Cytophagia Bacteria 2DVV4@1,33XBE@2,47V12@768503,4P35H@976 NA|NA|NA S Domain of unknown function (DUF4382) MAG.T22.3_02678 1239962.C943_02345 2.6e-239 834.3 Cytophagia dgt GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 ko:K01129 ko00230,map00230 R01856 RC00017 ko00000,ko00001,ko01000 iJN678.dgt Bacteria 47KD3@768503,4NENM@976,COG0232@1,COG0232@2 NA|NA|NA F Deoxyguanosinetriphosphate triphosphohydrolase-like protein MAG.T22.3_02679 1239962.C943_02344 9e-259 899.0 Cytophagia fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 Bacteria 47JKQ@768503,4NEQP@976,COG0114@1,COG0114@2 NA|NA|NA C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate MAG.T22.3_02680 1239962.C943_02343 5e-273 946.4 Cytophagia icd 1.1.1.41,1.1.1.42 ko:K00030,ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R00709,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 47KD2@768503,4NGUA@976,COG0473@1,COG0473@2 NA|NA|NA CE Isocitrate dehydrogenase MAG.T22.3_02681 1239962.C943_02342 1.1e-58 232.3 Bacteria Bacteria 2EIEG@1,33C5W@2 NA|NA|NA MAG.T22.3_02683 1239962.C943_02339 1.5e-180 638.6 Cytophagia Bacteria 47NJ6@768503,4NJ3Z@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase domain protein TIM barrel MAG.T22.3_02684 866536.Belba_0822 3e-48 198.0 Cytophagia Bacteria 2FANV@1,342WI@2,47VN5@768503,4P4I0@976 NA|NA|NA MAG.T22.3_02685 1239962.C943_02336 6.9e-306 1055.8 Cytophagia 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 47KZQ@768503,4NF8C@976,COG0154@1,COG0154@2 NA|NA|NA J Amidase MAG.T22.3_02686 1239962.C943_02335 1.1e-147 529.3 Cytophagia dinD ko:K07741,ko:K14623 ko00000,ko03400 Bacteria 47TBU@768503,4NJ37@976,COG3645@1,COG3645@2 NA|NA|NA S DNA-damage-inducible protein D MAG.T22.3_02687 1239962.C943_02334 2.5e-198 698.0 Cytophagia solA Bacteria 47Q2W@768503,4NKQK@976,COG0665@1,COG0665@2 NA|NA|NA E FAD dependent oxidoreductase MAG.T22.3_02688 1239962.C943_02333 0.0 1265.0 Bacteroidetes pckG GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0016020,GO:0019725,GO:0030003,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071944,GO:0075136,GO:0098771 4.1.1.32,4.1.1.49 ko:K01596,ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 M00003,M00170 R00341,R00431,R00726 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2638 Bacteria 4NIPX@976,COG1274@1,COG1274@2 NA|NA|NA H Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle MAG.T22.3_02689 349521.HCH_01631 3.2e-07 62.8 Bacteria Bacteria 2ENQZ@1,33GC6@2 NA|NA|NA MAG.T22.3_02690 1123057.P872_00805 2.4e-09 69.3 Cytophagia Bacteria 2DGG4@1,2ZVUV@2,47WY5@768503,4P7R9@976 NA|NA|NA MAG.T22.3_02691 1239962.C943_02329 2e-285 987.6 Cytophagia gltD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450 Bacteria 47M2V@768503,4NG9R@976,COG0493@1,COG0493@2 NA|NA|NA E TIGRFAM glutamate synthases, NADH NADPH, small subunit MAG.T22.3_02692 1239962.C943_02328 0.0 2959.1 Cytophagia gltB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 Bacteria 47JB7@768503,4NFKH@976,COG0067@1,COG0067@2,COG0069@1,COG0069@2,COG0070@1,COG0070@2 NA|NA|NA E glutamate synthase MAG.T22.3_02693 1239962.C943_02327 2.6e-239 834.3 Cytophagia gldE Bacteria 47JUX@768503,4NDZ7@976,COG1253@1,COG1253@2 NA|NA|NA S TIGRFAM gliding motility-associated protein GldE MAG.T22.3_02694 1239962.C943_02326 1.5e-79 302.0 Cytophagia ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 47QZT@768503,4NQBK@976,COG0629@1,COG0629@2 NA|NA|NA L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism MAG.T22.3_02695 1239962.C943_02325 7.1e-203 713.0 Cytophagia mutY ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 47KTH@768503,4NDZY@976,COG1194@1,COG1194@2 NA|NA|NA L A G-specific adenine glycosylase MAG.T22.3_02696 1239962.C943_02324 2.2e-48 198.0 Cytophagia hupA ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 47QBN@768503,4NT0D@976,COG0776@1,COG0776@2 NA|NA|NA L Belongs to the bacterial histone-like protein family MAG.T22.3_02697 1239962.C943_02323 4e-89 334.7 Cytophagia Bacteria 47KT9@768503,4NEV2@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.3_02698 1239962.C943_02322 1.1e-292 1011.9 Cytophagia rng 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 47KC6@768503,4NED1@976,COG1530@1,COG1530@2 NA|NA|NA J ribonuclease, Rne Rng family MAG.T22.3_02699 1239962.C943_02321 1.8e-93 350.1 Cytophagia Bacteria 28MEY@1,2ZASH@2,47W47@768503,4NG12@976 NA|NA|NA S PQQ-like domain MAG.T22.3_02700 1239962.C943_02320 1.4e-80 305.4 Cytophagia yehS Bacteria 47PTJ@768503,4NSYM@976,COG4807@1,COG4807@2 NA|NA|NA S Protein of unknown function (DUF1456) MAG.T22.3_02701 1239962.C943_02319 1.4e-128 465.7 Cytophagia ko:K09797 ko00000 Bacteria 47JV0@768503,4NI76@976,COG2859@1,COG2859@2 NA|NA|NA S Protein of unknown function (DUF541) MAG.T22.3_02702 1239962.C943_02318 1.5e-242 845.1 Cytophagia Bacteria 28M10@1,2ZAFW@2,47KHS@768503,4NIF8@976 NA|NA|NA S Domain of unknown function (DUF4403) MAG.T22.3_02703 1239962.C943_02316 9e-56 222.6 Cytophagia ytxJ ko:K20543 ko00000,ko02000 1.B.55.3 Bacteria 47R3Q@768503,4NSE6@976,COG3118@1,COG3118@2 NA|NA|NA O TIGRFAM bacillithiol system protein YtxJ MAG.T22.3_02704 1239962.C943_02315 2e-114 418.7 Cytophagia Bacteria 47RZ2@768503,4NMZ9@976,COG3714@1,COG3714@2 NA|NA|NA S PFAM YhhN-like protein MAG.T22.3_02705 1239962.C943_02314 0.0 2092.4 Cytophagia Bacteria 47JMC@768503,4NF66@976,COG1629@1,COG4771@2 NA|NA|NA P Carboxypeptidase regulatory-like domain MAG.T22.3_02706 1239962.C943_02307 1.6e-94 352.1 Cytophagia Bacteria 47RXN@768503,4NTUH@976,COG1514@1,COG1514@2 NA|NA|NA J 2'-5' RNA ligase MAG.T22.3_02707 1239962.C943_02306 1.1e-164 585.9 Cytophagia Bacteria 47PF0@768503,4NER9@976,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein MAG.T22.3_02709 1239962.C943_02304 0.0 1462.6 Cytophagia 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 R06620 RC00066 ko00000,ko00001,ko01000 Bacteria 47KDI@768503,4NFK0@976,COG4993@1,COG4993@2 NA|NA|NA G Pyrrolo-quinoline quinone MAG.T22.3_02710 1239962.C943_02303 1.7e-159 568.5 Cytophagia Bacteria 47NTV@768503,4NEH9@976,COG5285@1,COG5285@2 NA|NA|NA Q Phytanoyl-CoA dioxygenase (PhyH) MAG.T22.3_02711 1239962.C943_02776 1.2e-85 322.4 Cytophagia fur GO:0000976,GO:0001067,GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 ko:K03711 ko00000,ko03000 Bacteria 47P99@768503,4NM8S@976,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family MAG.T22.3_02712 1239962.C943_02777 6e-39 166.8 Cytophagia rsbV ko:K04749,ko:K06378 ko00000,ko03021 Bacteria 47R73@768503,4NTNE@976,COG1366@1,COG1366@2 NA|NA|NA T Belongs to the anti-sigma-factor antagonist family MAG.T22.3_02713 1239962.C943_02778 3.2e-239 833.9 Cytophagia purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 Bacteria 47JQ0@768503,4NGRZ@976,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP MAG.T22.3_02714 1239962.C943_02779 0.0 1442.6 Cytophagia Bacteria 47NDA@768503,4NIBR@976,COG3291@1,COG3291@2 NA|NA|NA S PKD domain MAG.T22.3_02715 1239962.C943_02780 1.1e-186 659.1 Cytophagia Bacteria 47TB6@768503,4NG13@976,COG4772@1,COG4772@2 NA|NA|NA P Pfam:DUF3308 MAG.T22.3_02716 1239962.C943_03968 2.3e-170 604.7 Cytophagia Bacteria 47NQB@768503,4NJF7@976,COG1082@1,COG1082@2 NA|NA|NA G PFAM Xylose isomerase-like TIM barrel MAG.T22.3_02717 1239962.C943_03967 2.4e-98 364.8 Bacteroidetes Bacteria 2CDAN@1,3134Z@2,4NNX4@976 NA|NA|NA S (twin-arginine translocation) pathway signal MAG.T22.3_02718 1239962.C943_03966 0.0 1145.6 Cytophagia Bacteria 47JQ2@768503,4NEF2@976,COG2303@1,COG2303@2 NA|NA|NA E PFAM glucose-methanol-choline oxidoreductase MAG.T22.3_02719 1239962.C943_03965 1.5e-166 592.0 Cytophagia gip 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 R01394 RC00511 ko00000,ko00001,ko01000 Bacteria 47M10@768503,4NG0V@976,COG3622@1,COG3622@2 NA|NA|NA G Belongs to the hyi family MAG.T22.3_02720 1239962.C943_03964 3.6e-211 740.7 Cytophagia yegT ko:K05820 ko00000,ko02000 2.A.1.27 Bacteria 47M36@768503,4PKJD@976,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T22.3_02721 1239962.C943_03962 7.9e-224 782.7 Cytophagia yisS Bacteria 47K95@768503,4NFMS@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.3_02722 1239962.C943_03960 6.6e-206 723.0 Cytophagia Bacteria 47M7V@768503,4NGBE@976,COG1082@1,COG1082@2 NA|NA|NA G AP endonuclease MAG.T22.3_02723 1239962.C943_03959 7.6e-60 236.5 Cytophagia ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 47X9M@768503,4NTWJ@976,COG4654@1,COG4654@2 NA|NA|NA C Cytochrome c MAG.T22.3_02724 1239962.C943_03958 1.7e-139 501.9 Cytophagia 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria 47NE6@768503,4PKJE@976,COG2133@1,COG2133@2 NA|NA|NA G Domain of Unknown Function (DUF1080) MAG.T22.3_02725 1239962.C943_03957 3.5e-148 531.2 Cytophagia Bacteria 2FIKD@1,34ACE@2,47WS7@768503,4P63W@976 NA|NA|NA MAG.T22.3_02726 1239962.C943_03956 8.5e-61 239.6 Bacteroidetes Bacteria 2BT0F@1,32N4H@2,4P7V0@976 NA|NA|NA MAG.T22.3_02727 1239962.C943_03954 1.5e-92 345.5 Cytophagia Bacteria 2CDAN@1,309X8@2,47QB3@768503,4NRN2@976 NA|NA|NA S Gluconate 2-dehydrogenase subunit 3 MAG.T22.3_02728 1239962.C943_03953 0.0 1165.2 Cytophagia Bacteria 47NME@768503,4NK1Z@976,COG2303@1,COG2303@2 NA|NA|NA E GMC oxidoreductase MAG.T22.3_02731 1239962.C943_03949 1.6e-65 255.4 Cytophagia Bacteria 47RW1@768503,4NUPH@976,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain MAG.T22.3_02732 1239962.C943_03948 9.1e-289 998.8 Cytophagia Bacteria 47MIE@768503,4NIH4@976,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase/protease-like homologues MAG.T22.3_02734 1239962.C943_03946 1.3e-162 578.9 Cytophagia Bacteria 47NC5@768503,4NHQ6@976,COG5285@1,COG5285@2 NA|NA|NA Q Phytanoyl-CoA dioxygenase (PhyH) MAG.T22.3_02735 1239962.C943_03944 4.6e-214 750.4 Cytophagia htpX_2 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 Bacteria 47KTS@768503,4NESF@976,COG0501@1,COG0501@2 NA|NA|NA O Zn-dependent protease with chaperone function MAG.T22.3_02736 1239962.C943_03943 1.4e-204 718.8 Cytophagia Bacteria 47MUX@768503,4NG13@976,COG4772@1,COG4772@2 NA|NA|NA P TIGRFAM Bacteroidetes-specific MAG.T22.3_02737 1239962.C943_03942 0.0 3549.2 Cytophagia Bacteria 47XAP@768503,4P1H8@976,COG3291@1,COG3291@2 NA|NA|NA S C-terminal domain of CHU protein family MAG.T22.3_02738 1239962.C943_01320 4.6e-311 1072.8 Cytophagia Bacteria 47NF5@768503,4NEZJ@976,COG3119@1,COG3119@2 NA|NA|NA P Sulfatase MAG.T22.3_02739 391603.FBALC1_01267 2.1e-38 167.9 Flavobacteriia CP_0766 2.7.13.3 ko:K07777,ko:K21449 ko02020,map02020 M00478 ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022 1.B.40.2 Bacteria 1IBNI@117743,4NWCU@976,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation MAG.T22.3_02740 1239962.C943_01445 9e-50 202.6 Bacteroidetes Bacteria 4NK36@976,COG1502@1,COG1502@2 NA|NA|NA I ORF6N domain MAG.T22.3_02741 1239962.C943_01445 1.3e-45 188.7 Bacteroidetes Bacteria 4NK36@976,COG1502@1,COG1502@2 NA|NA|NA I ORF6N domain MAG.T22.3_02742 1239962.C943_01446 4.3e-110 404.1 Cytophagia Bacteria 2BV2U@1,32QFS@2,47WTN@768503,4PC4K@976 NA|NA|NA MAG.T22.3_02743 1239962.C943_01447 9.1e-223 779.2 Bacteroidetes Bacteria 28H6R@1,2Z7J3@2,4P1VZ@976 NA|NA|NA S Psort location CytoplasmicMembrane, score MAG.T22.3_02745 1239962.C943_01449 1.3e-221 775.4 Cytophagia Bacteria 47Q5X@768503,4NHJS@976,COG1503@1,COG1503@2 NA|NA|NA J translation release factor activity MAG.T22.3_02746 1239962.C943_03008 5.1e-119 433.7 Cytophagia Bacteria 47MYP@768503,4NEZ7@976,COG1413@1,COG1413@2 NA|NA|NA C Domain of Unknown Function (DUF1080) MAG.T22.3_02747 1239962.C943_03007 2.5e-266 924.1 Cytophagia Bacteria 47KJR@768503,4NHDZ@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.3_02748 1239962.C943_03006 1.2e-117 429.1 Cytophagia tal GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 47JX6@768503,4NFVZ@976,COG0176@1,COG0176@2 NA|NA|NA G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway MAG.T22.3_02749 866536.Belba_2631 9e-27 125.6 Cytophagia Bacteria 2E6NQ@1,33195@2,47S5Y@768503,4NV7Z@976 NA|NA|NA MAG.T22.3_02750 1239962.C943_03004 3.4e-129 467.6 Cytophagia ftsE GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 47MP4@768503,4NEP2@976,COG2884@1,COG2884@2 NA|NA|NA D PFAM ABC transporter MAG.T22.3_02751 1239962.C943_03003 3.7e-244 850.5 Cytophagia Bacteria 47MG1@768503,4NFKJ@976,COG0793@1,COG0793@2 NA|NA|NA M PFAM Peptidase S41 MAG.T22.3_02752 1239962.C943_02999 4.3e-272 943.3 Cytophagia miaB GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 Bacteria 47MGS@768503,4NDU6@976,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine MAG.T22.3_02753 1239962.C943_02998 1.4e-234 818.5 Cytophagia nifA ko:K03413,ko:K13589 ko02020,ko02030,ko04112,map02020,map02030,map04112 M00506,M00512 ko00000,ko00001,ko00002,ko02022,ko02035 Bacteria 47JXW@768503,4NDWI@976,COG2204@1,COG2204@2 NA|NA|NA K sigma54 specific, transcriptional regulator, Fis family MAG.T22.3_02754 1239962.C943_02997 1.3e-90 339.0 Cytophagia lptE Bacteria 2CADI@1,32RR7@2,47P8C@768503,4NP51@976 NA|NA|NA S Lipopolysaccharide-assembly MAG.T22.3_02755 1239962.C943_02996 5.7e-128 463.8 Cytophagia Bacteria 2ECXC@1,336UI@2,47RWP@768503,4NV8T@976 NA|NA|NA MAG.T22.3_02756 1239962.C943_02995 5e-52 210.3 Cytophagia secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 47SC6@768503,4NUYQ@976,COG1314@1,COG1314@2 NA|NA|NA U PFAM Preprotein translocase SecG subunit MAG.T22.3_02757 1239962.C943_02994 2.1e-126 458.4 Cytophagia Bacteria 28KKN@1,2ZA5E@2,47PT5@768503,4NMKH@976 NA|NA|NA MAG.T22.3_02758 1239962.C943_02992 1.9e-43 181.4 Cytophagia groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 ko:K04078 ko00000,ko03029,ko03110 Bacteria 47QCW@768503,4NS7D@976,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter MAG.T22.3_02759 1239962.C943_02991 8.5e-293 1012.3 Cytophagia groL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 47JYW@768503,4NDZM@976,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions MAG.T22.3_02760 1239962.C943_02990 1.5e-62 245.4 Cytophagia Bacteria 47QY1@768503,4NR7W@976,COG3437@1,COG3437@2 NA|NA|NA T cheY-homologous receiver domain MAG.T22.3_02761 1239962.C943_02989 2e-183 648.3 Cytophagia corA GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 47JWS@768503,4NG3C@976,COG0598@1,COG0598@2 NA|NA|NA P Mediates influx of magnesium ions MAG.T22.3_02762 1239962.C943_02988 0.0 1946.4 Cytophagia Bacteria 47YIE@768503,4NRQR@976,COG4935@1,COG4935@2 NA|NA|NA O Belongs to the peptidase S8 family MAG.T22.3_02763 1239962.C943_02987 2.8e-199 701.0 Cytophagia proB GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 47KIA@768503,4NH75@976,COG0263@1,COG0263@2 NA|NA|NA E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate MAG.T22.3_02764 1239962.C943_02986 1.5e-220 771.9 Cytophagia proA GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iLJ478.TM0293,iYL1228.KPN_00280,iYO844.BSU13130 Bacteria 47J99@768503,4NEPQ@976,COG0014@1,COG0014@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate MAG.T22.3_02766 1239962.C943_02984 1.1e-68 265.8 Cytophagia ko:K09966 ko00000 Bacteria 47QRD@768503,4NQDE@976,COG3651@1,COG3651@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2237) MAG.T22.3_02768 1239962.C943_02982 2.9e-285 987.3 Cytophagia 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 47MKA@768503,4NG3D@976,COG1785@1,COG1785@2 NA|NA|NA P Belongs to the alkaline phosphatase family MAG.T22.3_02769 1239962.C943_02981 1.3e-61 242.3 Cytophagia MA20_19755 Bacteria 47QXP@768503,4NQ87@976,COG5349@1,COG5349@2 NA|NA|NA S Protein of unknown function (DUF983) MAG.T22.3_02770 1189612.A33Q_2882 1.5e-14 85.9 Cytophagia Bacteria 2DQ6E@1,334YJ@2,47SFY@768503,4NUXE@976 NA|NA|NA MAG.T22.3_02771 1239962.C943_02979 3.4e-158 564.3 Cytophagia Bacteria 28HDX@1,2Z7QG@2,47JZS@768503,4NFID@976 NA|NA|NA MAG.T22.3_02772 1239962.C943_02978 3.6e-31 140.2 Cytophagia Bacteria 2ECIG@1,336GN@2,47RWS@768503,4NX5X@976 NA|NA|NA MAG.T22.3_02773 866536.Belba_3440 6.8e-28 130.6 Cytophagia Bacteria 2E0HI@1,32W3C@2,47SU8@768503,4NQ7D@976 NA|NA|NA MAG.T22.3_02774 1239962.C943_02976 1.2e-88 332.4 Cytophagia Bacteria 2AN5I@1,31D3D@2,47QVV@768503,4NQTI@976 NA|NA|NA S Domain of unknown function (DUF4920) MAG.T22.3_02775 1239962.C943_02975 4.8e-118 430.6 Cytophagia msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 ko00000,ko01000 Bacteria 47PB4@768503,4NMAJ@976,COG0225@1,COG0225@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine MAG.T22.3_02776 1239962.C943_02974 7.4e-39 166.0 Cytophagia Bacteria 2DR7Y@1,33AM1@2,47T1D@768503,4NT7M@976 NA|NA|NA S Protein of unknown function (DUF3253) MAG.T22.3_02777 1239962.C943_02972 7.6e-97 359.8 Cytophagia ksgA1 Bacteria 47RVM@768503,4NPMV@976,COG3963@1,COG3963@2 NA|NA|NA I Ribosomal RNA adenine dimethylase MAG.T22.3_02778 1239962.C943_02971 0.0 1308.9 Cytophagia ko:K01138 ko00000,ko01000 Bacteria 47XJI@768503,4NFI9@976,COG1368@1,COG1368@2 NA|NA|NA M Sulfatase MAG.T22.3_02779 1239962.C943_02970 1.4e-231 808.5 Cytophagia Bacteria 28I02@1,2Z84Y@2,47KEC@768503,4NE8I@976 NA|NA|NA MAG.T22.3_02780 1239962.C943_02969 1.9e-207 728.4 Cytophagia Bacteria 47KTG@768503,4NGMH@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.3_02781 1239962.C943_02968 3.5e-274 950.3 Cytophagia icaA ko:K00786 ko00000,ko01000 Bacteria 47MCT@768503,4NH18@976,COG1215@1,COG1215@2 NA|NA|NA M glycosyl transferase family 2 MAG.T22.3_02782 1239962.C943_02967 4.9e-293 1013.1 Cytophagia 3.4.11.2,3.4.24.3 ko:K01256,ko:K01387 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002,ko02042 Bacteria 47X7V@768503,4NVTZ@976,COG1413@1,COG1413@2 NA|NA|NA C lyase activity MAG.T22.3_02783 1239962.C943_02966 3.6e-58 230.7 Cytophagia Bacteria 47Q8N@768503,4NQNT@976,COG0745@1,COG0745@2 NA|NA|NA KT cheY-homologous receiver domain MAG.T22.3_02785 1239962.C943_02965 3.6e-310 1070.1 Cytophagia Bacteria 47N43@768503,4NHGA@976,COG1228@1,COG1228@2 NA|NA|NA Q Amidohydrolase family MAG.T22.3_02786 1239962.C943_02964 1.1e-261 908.7 Cytophagia Bacteria 47JC0@768503,4NF27@976,COG1228@1,COG1228@2 NA|NA|NA Q PFAM amidohydrolase MAG.T22.3_02787 1239962.C943_02963 5.6e-239 833.2 Cytophagia Bacteria 47M6X@768503,4NE5U@976,COG1228@1,COG1228@2 NA|NA|NA Q PFAM Amidohydrolase family MAG.T22.3_02788 1239962.C943_02962 2.1e-49 201.4 Cytophagia ybjQ Bacteria 47QED@768503,4NQGB@976,COG0393@1,COG0393@2 NA|NA|NA S Belongs to the UPF0145 family MAG.T22.3_02789 1239962.C943_02961 6.8e-117 427.2 Bacteria Bacteria COG3595@1,COG3595@2 NA|NA|NA MAG.T22.3_02791 1239962.C943_02959 2.5e-239 834.3 Cytophagia metY 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 iNJ661.Rv3340 Bacteria 47M8Z@768503,4NE27@976,COG2873@1,COG2873@2 NA|NA|NA E PFAM Cys Met metabolism PLP-dependent enzyme MAG.T22.3_02792 1239962.C943_02958 5e-201 706.8 Cytophagia metXA 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 R01776 RC00004,RC00041 ko00000,ko00001,ko01000 Bacteria 47KMZ@768503,4NFG2@976,COG2021@1,COG2021@2 NA|NA|NA E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine MAG.T22.3_02793 1239962.C943_02957 3.4e-59 234.2 Cytophagia Bacteria 47QSC@768503,4NRSZ@976,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MAG.T22.3_02795 1239962.C943_02955 2.5e-74 284.6 Cytophagia Bacteria 47R93@768503,4NQCK@976,COG4731@1,COG4731@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2147) MAG.T22.3_02797 1239962.C943_02953 1.7e-149 535.4 Cytophagia ftsX GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976 ko:K09811,ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 47KM1@768503,4NH05@976,COG2177@1,COG2177@2 NA|NA|NA D Belongs to the ABC-4 integral membrane protein family. FtsX subfamily MAG.T22.3_02798 1189612.A33Q_2942 4.3e-16 89.7 Cytophagia Bacteria 2DQ4W@1,334SC@2,47RZV@768503,4NUQX@976 NA|NA|NA S Protein of unknown function (DUF3098) MAG.T22.3_02799 1239962.C943_02951 5.7e-133 480.3 Cytophagia uppP 3.6.1.27 ko:K06153 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 47KGZ@768503,4NGIZ@976,COG1968@1,COG1968@2 NA|NA|NA V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin MAG.T22.3_02800 1239962.C943_02950 1.4e-119 435.6 Cytophagia truB GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481 5.4.99.25 ko:K03177 ko00000,ko01000,ko03016 Bacteria 47P98@768503,4NESK@976,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs MAG.T22.3_02801 1239962.C943_02949 7.5e-177 626.3 Cytophagia ribF 2.7.1.26,2.7.7.2 ko:K07011,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 47JNP@768503,4NEI9@976,COG0196@1,COG0196@2 NA|NA|NA H Belongs to the ribF family MAG.T22.3_02802 1189612.A33Q_2946 2.3e-114 418.3 Cytophagia scoA 2.8.3.5 ko:K01027,ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 R00410 RC00014 ko00000,ko00001,ko01000 Bacteria 47KQE@768503,4NF3T@976,COG1788@1,COG1788@2 NA|NA|NA I 3-oxoacid CoA-transferase, a subunit MAG.T22.3_02803 866536.Belba_3566 2.2e-106 391.7 Cytophagia scoB 2.8.3.5 ko:K01027,ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 R00410 RC00014 ko00000,ko00001,ko01000 Bacteria 47K21@768503,4NG9J@976,COG2057@1,COG2057@2 NA|NA|NA I TIGRFAM 3-oxoacid CoA-transferase, B subunit MAG.T22.3_02804 1239962.C943_02947 0.0 3321.6 Cytophagia Bacteria 47K9M@768503,4NFAX@976,COG1572@1,COG1572@2 NA|NA|NA S Peptidase family C25 MAG.T22.3_02805 1239962.C943_02946 7.5e-168 596.7 Cytophagia Bacteria 47KIV@768503,4NE43@976,COG2067@1,COG2067@2 NA|NA|NA I long-chain fatty acid transport protein MAG.T22.3_02806 1239962.C943_02944 6.1e-49 199.9 Cytophagia padR ko:K10947 ko00000,ko03000 Bacteria 47Q8F@768503,4NSI4@976,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator MAG.T22.3_02807 1239962.C943_02943 0.0 1182.9 Cytophagia ko:K03973 ko00000,ko02048,ko03000 Bacteria 47M43@768503,4NG3T@976,COG1983@1,COG1983@2 NA|NA|NA KT PFAM PspC domain MAG.T22.3_02808 1239962.C943_02942 1.2e-271 941.8 Cytophagia ko:K07576 ko00000 Bacteria 47K9F@768503,4NESD@976,COG1236@1,COG1236@2 NA|NA|NA J exonuclease of the beta-lactamase fold involved in RNA processing MAG.T22.3_02809 1250005.PHEL85_1534 1.9e-07 62.8 Polaribacter Bacteria 1ICCS@117743,3VWV1@52959,4NR9K@976,COG3637@1,COG3637@2 NA|NA|NA M Outer membrane protein beta-barrel domain MAG.T22.3_02810 1239962.C943_02940 6e-71 273.5 Cytophagia Bacteria 47QG5@768503,4NQ7Z@976,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain MAG.T22.3_02811 1239962.C943_02939 7.9e-216 756.1 Bacteria Bacteria COG0624@1,COG0624@2 NA|NA|NA E succinyl-diaminopimelate desuccinylase activity MAG.T22.3_02812 1239962.C943_02938 4.3e-211 740.3 Cytophagia 1.14.19.3 ko:K00508 ko00591,ko01100,map00591,map01100 R07063 RC00917 ko00000,ko00001,ko01000,ko01004 Bacteria 47TX7@768503,4NERD@976,COG3239@1,COG3239@2 NA|NA|NA I Fatty acid desaturase MAG.T22.3_02813 1239962.C943_02936 1.1e-290 1005.4 Cytophagia mscS ko:K05802,ko:K16052 ko00000,ko02000 1.A.23.1.1,1.A.23.4 Bacteria 47P1K@768503,4PMEF@976,COG3264@1,COG3264@2 NA|NA|NA M Mechanosensitive ion channel MAG.T22.3_02814 1239962.C943_02244 9.1e-43 180.6 Bacteria Bacteria COG2067@1,COG2067@2 NA|NA|NA I long-chain fatty acid transporting porin activity MAG.T22.3_02815 1239962.C943_02934 8.6e-83 313.2 Cytophagia ko:K03088 ko00000,ko03021 Bacteria 47PTY@768503,4NQCH@976,COG1595@1,COG1595@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family MAG.T22.3_02816 1239962.C943_02933 7.2e-106 390.2 Cytophagia Bacteria 2EG8W@1,33A0P@2,47T68@768503,4NXXY@976 NA|NA|NA MAG.T22.3_02817 1239962.C943_02932 4.7e-196 690.3 Cytophagia Bacteria 29XBU@1,30J1I@2,47PM3@768503,4PMD4@976 NA|NA|NA MAG.T22.3_02818 1239962.C943_02931 1.2e-143 515.8 Cytophagia rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 47Y4X@768503,4NG2I@976,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates MAG.T22.3_02819 1239962.C943_02930 1.8e-106 392.5 Cytophagia Bacteria 47PEC@768503,4NMHT@976,COG3595@1,COG3595@2 NA|NA|NA S Putative adhesin MAG.T22.3_02820 1239962.C943_02929 1.8e-164 585.1 Cytophagia yghX 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 47JGG@768503,4NEUX@976,COG0412@1,COG0412@2 NA|NA|NA Q dienelactone hydrolase MAG.T22.3_02821 1239962.C943_02928 1.3e-154 552.4 Cytophagia Bacteria 2BZ6M@1,2Z7HW@2,47M8V@768503,4NDZE@976 NA|NA|NA S Domain of Unknown Function (DUF1080) MAG.T22.3_02822 1239962.C943_02927 8.3e-82 309.7 Cytophagia Bacteria 2DM9Y@1,32AJ6@2,47PRQ@768503,4NQQC@976 NA|NA|NA MAG.T22.3_02823 1239962.C943_02926 3.6e-124 451.1 Cytophagia Bacteria 47QXX@768503,4NRCD@976,COG3568@1,COG3568@2 NA|NA|NA S Endonuclease/Exonuclease/phosphatase family MAG.T22.3_02824 1239962.C943_02925 4.6e-79 300.4 Cytophagia ko:K07182 ko00000 Bacteria 47QRM@768503,4NNFS@976,COG0517@1,COG0517@2 NA|NA|NA S Domain in cystathionine beta-synthase and other proteins. MAG.T22.3_02825 1239962.C943_02924 2.8e-264 917.5 Cytophagia Bacteria 47K44@768503,4NFKR@976,COG4636@1,COG4636@2 NA|NA|NA S Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MAG.T22.3_02826 1239962.C943_02923 7.6e-87 326.6 Cytophagia maa 2.3.1.79 ko:K00661 ko00000,ko01000 Bacteria 47UEG@768503,4NH27@976,COG0110@1,COG0110@2 NA|NA|NA S Maltose acetyltransferase MAG.T22.3_02827 1239962.C943_02922 3.2e-130 471.1 Cytophagia cutC GO:0006873,GO:0006875,GO:0006878,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0019725,GO:0030003,GO:0042221,GO:0042592,GO:0046688,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 ko:K06201 ko00000 Bacteria 47NRE@768503,4NINY@976,COG3142@1,COG3142@2 NA|NA|NA P Participates in the control of copper homeostasis MAG.T22.3_02828 1239962.C943_02921 1.4e-181 642.1 Cytophagia aspG 3.4.19.5,3.5.1.1,3.5.1.26 ko:K01424,ko:K01444,ko:K13051 ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142 R00485 RC00010,RC02798 ko00000,ko00001,ko01000,ko01002 Bacteria 47JDT@768503,4NE3D@976,COG1446@1,COG1446@2 NA|NA|NA E PFAM peptidase T2 asparaginase 2 MAG.T22.3_02829 102129.Lepto7375DRAFT_5685 7.2e-28 130.2 Oscillatoriales ko:K18828 ko00000,ko01000,ko02048,ko03016 Bacteria 1G6XP@1117,1HCXG@1150,COG1487@1,COG1487@2 NA|NA|NA S Toxic component of a toxin-antitoxin (TA) module. An RNase MAG.T22.3_02831 1239962.C943_02919 8.7e-147 526.2 Cytophagia crnA 3.5.2.10 ko:K01470 ko00330,map00330 R01884 RC00615 ko00000,ko00001,ko01000 Bacteria 47MQ8@768503,4NF2C@976,COG1402@1,COG1402@2 NA|NA|NA S Creatinine amidohydrolase MAG.T22.3_02832 1239962.C943_02918 1.4e-215 755.4 Cytophagia atoB 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 iJN746.PP_2215 Bacteria 47JS8@768503,4NE3Q@976,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family MAG.T22.3_02833 1239962.C943_02917 3.8e-103 381.3 Cytophagia Bacteria 47RXC@768503,4PP7F@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.3_02834 1239962.C943_02916 3.7e-171 607.4 Cytophagia ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 47NJQ@768503,4NF7Y@976,COG2304@1,COG2304@2 NA|NA|NA S PFAM von Willebrand factor type A MAG.T22.3_02835 1239962.C943_02915 0.0 1583.9 Cytophagia Bacteria 47JN3@768503,4NF4B@976,COG1629@1,COG4771@2 NA|NA|NA P TonB-dependent Receptor Plug MAG.T22.3_02836 1239962.C943_02914 1.9e-150 538.5 Cytophagia Bacteria 2DN4I@1,32VGS@2,47RGS@768503,4NNY4@976 NA|NA|NA S Domain of unknown function (DUF4249) MAG.T22.3_02837 1239962.C943_02913 2.2e-151 541.6 Cytophagia mvaB 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 Bacteria 47KB5@768503,4NDZH@976,COG0119@1,COG0119@2 NA|NA|NA E Isopropylmalate homocitrate citramalate synthase MAG.T22.3_02838 1239962.C943_02911 4.2e-22 110.5 Bacteroidetes Bacteria 296VH@1,2ZU4C@2,4P6VG@976 NA|NA|NA MAG.T22.3_02839 1239962.C943_02909 2.7e-182 644.4 Cytophagia metF 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 Bacteria 47KQ7@768503,4NDY0@976,COG0685@1,COG0685@2 NA|NA|NA E Methylenetetrahydrofolate reductase MAG.T22.3_02840 1189612.A33Q_2916 0.0 1507.3 Cytophagia metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13,2.1.1.245,2.1.1.258 ko:K00197,ko:K00548,ko:K15023 ko00270,ko00450,ko00670,ko00680,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00680,map00720,map01100,map01110,map01120,map01200,map01230 M00017,M00357,M00377,M00422 R00946,R02289,R09096,R09365,R10219,R10243 RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977 ko00000,ko00001,ko00002,ko01000 Bacteria 47XZT@768503,4PKI8@976,COG1410@1,COG1410@2 NA|NA|NA E B12 binding domain MAG.T22.3_02841 1189612.A33Q_2917 2.2e-169 601.7 Cytophagia metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545 Bacteria 47KPH@768503,4NFRF@976,COG0646@1,COG0646@2 NA|NA|NA E Homocysteine S-methyltransferase MAG.T22.3_02844 1239962.C943_02907 4.2e-90 337.4 Cytophagia Bacteria 47QAB@768503,4NPF9@976,COG0251@1,COG0251@2 NA|NA|NA J translation initiation inhibitor, yjgF family MAG.T22.3_02845 1239962.C943_02906 7.2e-236 822.8 Cytophagia Bacteria 28KUU@1,2ZABH@2,47MRH@768503,4NHH1@976 NA|NA|NA MAG.T22.3_02846 1239962.C943_02905 0.0 2756.9 Cytophagia 2.7.13.3 ko:K02482,ko:K19616 ko02020,map02020 M00771 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 47Y55@768503,4PM99@976,COG2203@1,COG2203@2,COG4251@1,COG4251@2 NA|NA|NA T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) MAG.T22.3_02847 1239962.C943_02904 0.0 1962.2 Cytophagia Bacteria 47JFY@768503,4NDVD@976,COG1506@1,COG1506@2 NA|NA|NA E Prolyl oligopeptidase family MAG.T22.3_02849 1239962.C943_02902 5.3e-262 909.8 Cytophagia Bacteria 47KN4@768503,4NDZK@976,COG1538@1,COG1538@2 NA|NA|NA MU TIGRFAM efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family MAG.T22.3_02850 1239962.C943_02901 0.0 1975.7 Cytophagia ko:K03296 ko00000 2.A.6.2 Bacteria 47JKS@768503,4NDZG@976,COG0841@1,COG0841@2 NA|NA|NA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MAG.T22.3_02851 1239962.C943_02900 5e-186 657.1 Cytophagia acrA ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 Bacteria 47K2C@768503,4NEXN@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.3_02854 1239962.C943_02897 3.5e-174 617.5 Cytophagia fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000 Bacteria 47JDP@768503,4NE8U@976,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus MAG.T22.3_02855 1123057.P872_24330 2.3e-67 262.7 Cytophagia Bacteria 2DH2A@1,2ZY56@2,47U1R@768503,4PAN0@976 NA|NA|NA S Domain of unknown function (DUF4412) MAG.T22.3_02856 1239962.C943_02895 4.4e-83 313.9 Cytophagia folA 1.5.1.3 ko:K00287,ko:K18589 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 47Q9G@768503,4NQ2Y@976,COG0262@1,COG0262@2 NA|NA|NA H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis MAG.T22.3_02857 1239962.C943_02894 3.8e-232 810.4 Cytophagia cinA 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 47JN4@768503,4NDVV@976,COG1058@1,COG1058@2,COG1546@1,COG1546@2 NA|NA|NA S CinA-like protein MAG.T22.3_02858 1239962.C943_02893 6.9e-229 799.7 Cytophagia bfmBB 2.3.1.168,2.3.1.61 ko:K00658,ko:K09699 ko00020,ko00280,ko00310,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00280,map00310,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032,M00036 R02570,R02571,R02662,R03174,R04097,R08549,R10998 RC00004,RC02727,RC02833,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 47JDY@768503,4NED0@976,COG0508@1,COG0508@2 NA|NA|NA C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex MAG.T22.3_02859 1239962.C943_02892 0.0 1848.6 Bacteria Bacteria COG5002@1,COG5002@2 NA|NA|NA T protein histidine kinase activity MAG.T22.3_02860 1123057.P872_24365 3.4e-90 338.6 Cytophagia Bacteria 47U80@768503,4P030@976,COG2199@1,COG3706@2 NA|NA|NA T GGDEF domain MAG.T22.3_02861 1239962.C943_02890 2.5e-36 157.5 Cytophagia Bacteria 2E35A@1,32Y59@2,47S3U@768503,4NVFH@976 NA|NA|NA MAG.T22.3_02862 1239962.C943_02889 1.5e-59 235.3 Bacteroidetes yhfA ko:K07397 ko00000 Bacteria 4NNTY@976,COG1765@1,COG1765@2 NA|NA|NA O redox protein regulator of disulfide bond formation MAG.T22.3_02863 1239962.C943_02888 0.0 2154.0 Cytophagia icmF GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 ko:K11942 ko00000,ko01000 Bacteria 47KS7@768503,4NFHX@976,COG1703@1,COG1703@2,COG1884@1,COG1884@2,COG2185@1,COG2185@2 NA|NA|NA EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly MAG.T22.3_02864 1239962.C943_02887 1.6e-194 685.3 Cytophagia rip3 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K06212,ko:K06402 ko00000,ko01000,ko01002,ko02000 1.A.16.1.1,1.A.16.1.3 Bacteria 47NFI@768503,4NK8R@976,COG0517@1,COG0517@2,COG1994@1,COG1994@2 NA|NA|NA S Peptidase family M50 MAG.T22.3_02865 1239962.C943_02886 0.0 1637.5 Cytophagia 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 47JYI@768503,4NERM@976,COG0474@1,COG0474@2 NA|NA|NA P ATPase, P-type (transporting), HAD superfamily, subfamily IC MAG.T22.3_02866 1239962.C943_02885 0.0 1427.2 Cytophagia susB GO:0000272,GO:0003674,GO:0003824,GO:0004339,GO:0004553,GO:0004558,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015926,GO:0016020,GO:0016052,GO:0016787,GO:0016798,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:0090599,GO:1901575 3.2.1.20,3.2.1.3 ko:K01187,ko:K21574 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R01790,R01791,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 GH31,GH97 Bacteria 47JIF@768503,4NEWC@976,COG1082@1,COG1082@2 NA|NA|NA G Glycoside hydrolase 97 MAG.T22.3_02867 1239962.C943_02883 3.7e-282 976.9 Cytophagia sacC GO:0003674,GO:0003824,GO:0004553,GO:0004564,GO:0005975,GO:0005984,GO:0005985,GO:0005987,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016787,GO:0016798,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575 3.2.1.65,3.2.1.80 ko:K01212,ko:K03332 ko00051,ko00500,map00051,map00500 R00879,R05624,R11311 RC03278 ko00000,ko00001,ko01000 GH32 Bacteria 47KIP@768503,4NEYI@976,COG1621@1,COG1621@2 NA|NA|NA G Belongs to the glycosyl hydrolase 32 family MAG.T22.3_02868 1239962.C943_02882 0.0 1890.5 Cytophagia addB 3.1.11.5,3.6.4.12 ko:K01144,ko:K02259,ko:K16899 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko01000,ko03029,ko03400 3.D.4.4 Bacteria 47JB6@768503,4NFZQ@976,COG2887@1,COG2887@2,COG3893@1,COG3893@2 NA|NA|NA L PD-(D/E)XK nuclease superfamily MAG.T22.3_02870 1239962.C943_02880 6.9e-92 343.2 Cytophagia ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972,ko:K12472 ko03030,ko03410,ko03420,ko03430,ko04144,map03030,map03410,map03420,map03430,map04144 R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400,ko04131 Bacteria 47WXG@768503,4NRM8@976,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA MAG.T22.3_02871 1239962.C943_02879 1.1e-243 849.0 Cytophagia Bacteria 47KI3@768503,4NDUF@976,COG0534@1,COG0534@2 NA|NA|NA V PFAM Multi antimicrobial extrusion protein MatE MAG.T22.3_02872 1239962.C943_02878 0.0 1438.3 Cytophagia plpD ko:K07001 ko00000 Bacteria 47U9U@768503,4NDXY@976,COG1752@1,COG1752@2,COG4775@1,COG4775@2 NA|NA|NA M Patatin-like phospholipase MAG.T22.3_02873 1239962.C943_02877 1.5e-161 575.5 Cytophagia Bacteria 47STU@768503,4NZGM@976,COG3965@1,COG3965@2 NA|NA|NA P Cation efflux family MAG.T22.3_02874 1239962.C943_02876 8.9e-93 346.3 Bacteroidetes Bacteria 4NRS6@976,COG3279@1,COG3279@2 NA|NA|NA KT LytTr DNA-binding domain MAG.T22.3_02875 1239962.C943_02875 9.6e-225 785.8 Cytophagia 1.13.11.3 ko:K00449 ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220 R01631,R03549 RC00388,RC00953 br01602,ko00000,ko00001,ko01000 Bacteria 47QHP@768503,4NEZ1@976,COG3485@1,COG3485@2 NA|NA|NA Q Dioxygenase MAG.T22.3_02876 1239962.C943_02874 4.7e-118 430.6 Cytophagia yafK Bacteria 47PW3@768503,4NNK3@976,COG3034@1,COG3034@2 NA|NA|NA M ErfK YbiS YcfS YnhG family protein MAG.T22.3_02877 1239962.C943_02873 5.1e-303 1046.6 Cytophagia 3.4.24.84 ko:K03799,ko:K06013 ko00900,ko01130,map00900,map01130 M00743 R09845 RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko04147 Bacteria 47KFF@768503,4NFV7@976,COG0501@1,COG0501@2 NA|NA|NA O Peptidase family M48 MAG.T22.3_02878 1239962.C943_02871 5.5e-70 270.4 Cytophagia 3.1.31.1 ko:K01174 ko00000,ko01000 Bacteria 47RZB@768503,4NT3S@976,COG1525@1,COG1525@2 NA|NA|NA L Staphylococcal nuclease homologues MAG.T22.3_02879 1239962.C943_02870 7.5e-185 652.9 Cytophagia Bacteria 47N28@768503,4NG3B@976,COG5285@1,COG5285@2 NA|NA|NA Q Phytanoyl-CoA dioxygenase (PhyH) MAG.T22.3_02880 1239962.C943_02869 6.2e-88 330.1 Cytophagia csaA ko:K06878 ko00000 Bacteria 47RVU@768503,4NW07@976,COG4430@1,COG4430@2 NA|NA|NA S Bacteriocin-protection, YdeI or OmpD-Associated MAG.T22.3_02882 1239962.C943_03096 1.5e-142 512.3 Cytophagia hmuT ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 47K93@768503,4NH3G@976,COG4558@1,COG4558@2 NA|NA|NA P ABC-type hemin transport system, periplasmic component MAG.T22.3_02883 1239962.C943_03097 9.9e-280 968.8 Cytophagia atpD 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 Bacteria 47KRX@768503,4NF1Q@976,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits MAG.T22.3_02884 1239962.C943_03098 1.2e-36 158.7 Bacteroidetes atpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iHN637.CLJU_RS01195,iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190 Bacteria 4NUYG@976,COG0355@1,COG0355@2 NA|NA|NA C ATP synthase, Delta Epsilon MAG.T22.3_02885 1239962.C943_03100 4e-24 116.7 Cytophagia rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02970 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47RU4@768503,4NUPV@976,COG0828@1,COG0828@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS21 family MAG.T22.3_02886 1239962.C943_03101 5.8e-163 580.1 Cytophagia xerC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 47JJY@768503,4NGQW@976,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family MAG.T22.3_02887 1239962.C943_03102 1.2e-46 192.2 Cytophagia hpf ko:K05808,ko:K05809 ko00000,ko03009 Bacteria 47RC7@768503,4NUME@976,COG1544@1,COG1544@2 NA|NA|NA J PFAM Sigma 54 modulation protein S30EA ribosomal protein MAG.T22.3_02888 1239962.C943_03103 3e-218 764.2 Cytophagia chrA ko:K07240 ko00000,ko02000 2.A.51.1 Bacteria 47JQS@768503,4NNZ1@976,COG2059@1,COG2059@2 NA|NA|NA P TIGRFAM chromate transporter, chromate ion transporter (CHR) family MAG.T22.3_02889 1239962.C943_03104 7.4e-183 646.4 Cytophagia Bacteria 47JDX@768503,4NED5@976,COG3491@1,COG3491@2 NA|NA|NA C Belongs to the iron ascorbate-dependent oxidoreductase family MAG.T22.3_02890 1239962.C943_03105 3.1e-112 411.4 Bacteria Bacteria 2DD7X@1,2ZGYM@2 NA|NA|NA MAG.T22.3_02891 1239962.C943_03106 9.8e-220 769.2 Cytophagia serS 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 47JAB@768503,4NED6@976,COG0172@1,COG0172@2 NA|NA|NA J tRNA synthetase class II core domain (G, H, P, S and T) MAG.T22.3_02892 1239962.C943_03107 0.0 1438.7 Cytophagia pep GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 ko:K01322 ko04614,map04614 ko00000,ko00001,ko01000,ko01002 Bacteria 47JBG@768503,4NFJS@976,COG1505@1,COG1505@2 NA|NA|NA E PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain MAG.T22.3_02893 1239962.C943_03108 5.6e-72 276.9 Bacteria Bacteria 2EGCH@1,33A4A@2 NA|NA|NA S Putative lumazine-binding MAG.T22.3_02894 1239962.C943_03109 2.6e-248 864.4 Bacteria Bacteria COG3210@1,COG3210@2 NA|NA|NA U domain, Protein MAG.T22.3_02895 1239962.C943_03110 4.5e-209 734.6 Bacteria Bacteria COG3210@1,COG3210@2 NA|NA|NA U domain, Protein MAG.T22.3_02896 1239962.C943_03111 1.1e-109 404.1 Bacteria Bacteria COG3210@1,COG3210@2 NA|NA|NA U domain, Protein MAG.T22.3_02897 1239962.C943_03113 8.2e-288 995.7 Cytophagia Bacteria 47TH3@768503,4NIBK@976,COG5276@1,COG5276@2 NA|NA|NA S repeat protein MAG.T22.3_02898 1120966.AUBU01000008_gene2403 2.6e-58 233.8 Bacteria Bacteria COG3210@1,COG3210@2 NA|NA|NA U domain, Protein MAG.T22.3_02899 1123057.P872_00250 5.4e-46 193.0 Cytophagia ko:K21449 ko00000,ko02000 1.B.40.2 Bacteria 47SG9@768503,4NTT0@976,COG1361@1,COG1361@2,COG3210@1,COG3210@2,COG3291@1,COG3291@2 NA|NA|NA MU Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end MAG.T22.3_02900 1239962.C943_01587 4.4e-257 894.0 Bacteria 3.2.1.80 ko:K03332 ko00051,map00051 R00879 ko00000,ko00001,ko01000 Bacteria COG4733@1,COG4733@2 NA|NA|NA S cellulase activity MAG.T22.3_02901 1239962.C943_01587 0.0 1343.6 Bacteria 3.2.1.80 ko:K03332 ko00051,map00051 R00879 ko00000,ko00001,ko01000 Bacteria COG4733@1,COG4733@2 NA|NA|NA S cellulase activity MAG.T22.3_02902 1239962.C943_01589 0.0 1091.3 Cytophagia rho GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K02887,ko:K03628 ko03010,ko03018,map03010,map03018 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021 Bacteria 47JWD@768503,4NEFP@976,COG1158@1,COG1158@2 NA|NA|NA K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template MAG.T22.3_02903 1239962.C943_01590 7.1e-124 449.9 Cytophagia recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 47K9Z@768503,4NIBQ@976,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination MAG.T22.3_02904 1123057.P872_00195 1.9e-90 338.6 Cytophagia tdk GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 iLJ478.TM0401 Bacteria 47JA6@768503,4NE5R@976,COG1435@1,COG1435@2 NA|NA|NA F thymidine kinase MAG.T22.3_02905 1239962.C943_01592 2.6e-33 147.5 Bacteria GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 ko:K04755,ko:K08952,ko:K08953,ko:K08954 ko00000,ko00194 Bacteria COG0633@1,COG0633@2 NA|NA|NA C Ferredoxin MAG.T22.3_02906 1239962.C943_01593 1.1e-212 745.7 Cytophagia 3.2.1.8 ko:K01181,ko:K03832 ko00000,ko01000,ko02000 2.C.1.1 Bacteria 47NZ2@768503,4NES0@976,COG0810@1,COG0810@2 NA|NA|NA M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins MAG.T22.3_02907 1239962.C943_01595 1.7e-102 378.6 Cytophagia yueE ko:K06950 ko00000 Bacteria 47PQZ@768503,4NFAG@976,COG1418@1,COG1418@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. MAG.T22.3_02908 1239962.C943_01596 0.0 1828.5 Cytophagia polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 47KYI@768503,4NDVA@976,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity MAG.T22.3_02909 1239962.C943_01597 6e-95 353.6 Cytophagia Bacteria 28P8J@1,2ZC2G@2,47SAC@768503,4NTQZ@976 NA|NA|NA MAG.T22.3_02910 1239962.C943_01599 0.0 2426.4 Cytophagia Bacteria 2BZ4R@1,3344Z@2,47TU6@768503,4NX0J@976 NA|NA|NA MAG.T22.3_02911 1239962.C943_01600 1.4e-71 275.4 Bacteroidetes Bacteria 2E3B3@1,32X8G@2,4NTW7@976 NA|NA|NA S Protein of Unknown function (DUF2784) MAG.T22.3_02912 1239962.C943_01605 0.0 1140.9 Cytophagia 4.2.1.25 ko:K13875 ko00053,ko01100,map00053,map01100 R02522 RC00543 ko00000,ko00001,ko01000 Bacteria 47K3U@768503,4NEKY@976,COG0129@1,COG0129@2 NA|NA|NA EG Belongs to the IlvD Edd family MAG.T22.3_02913 1239962.C943_01606 4.9e-134 483.8 Cytophagia Bacteria 47MEC@768503,4NF64@976,COG1028@1,COG1028@2 NA|NA|NA IQ PFAM Short-chain dehydrogenase reductase SDR MAG.T22.3_02914 1239962.C943_01607 6.7e-78 296.6 Cytophagia yisT Bacteria 47S2U@768503,4NSE5@976,COG2318@1,COG2318@2 NA|NA|NA S DinB family MAG.T22.3_02915 1239962.C943_01608 1.8e-110 405.2 Cytophagia Bacteria 2E29H@1,32X6D@2,47RCG@768503,4NSA2@976 NA|NA|NA S Acetoacetate decarboxylase (ADC) MAG.T22.3_02916 1239962.C943_01609 4.6e-132 477.2 Cytophagia ko:K07124 ko00000 Bacteria 47W5Q@768503,4NRY9@976,COG0300@1,COG0300@2 NA|NA|NA S Enoyl-(Acyl carrier protein) reductase MAG.T22.3_02917 1239962.C943_01610 1.3e-119 435.6 Cytophagia Bacteria 2BSBY@1,32MDT@2,47X12@768503,4PIJQ@976 NA|NA|NA MAG.T22.3_02918 1239962.C943_01611 7.9e-233 812.8 Cytophagia cpg2_2 3.4.17.11 ko:K01295 ko00000,ko01000,ko01002 Bacteria 47NB9@768503,4NI66@976,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain MAG.T22.3_02919 50960.LS81_07910 1.6e-07 64.3 Epsilonproteobacteria ko:K07448 ko00000,ko02048 Bacteria 1QV0S@1224,29WBX@1,2YQDZ@29547,30HXH@2,42VX3@68525 NA|NA|NA V Restriction endonuclease MAG.T22.3_02921 1239962.C943_01611 4.6e-21 106.3 Cytophagia cpg2_2 3.4.17.11 ko:K01295 ko00000,ko01000,ko01002 Bacteria 47NB9@768503,4NI66@976,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain MAG.T22.3_02922 1121887.AUDK01000001_gene455 1.6e-28 132.9 Flavobacteriia Bacteria 1IJW2@117743,4PMNR@976,COG1426@1,COG1426@2 NA|NA|NA K Helix-turn-helix domain MAG.T22.3_02923 717231.Flexsi_0306 4e-11 74.3 Deferribacteres Bacteria 2GGPA@200930,COG2361@1,COG2361@2 NA|NA|NA S Protein of unknown function DUF86 MAG.T22.3_02924 1239962.C943_01612 0.0 1196.8 Cytophagia amyA Bacteria 47JQH@768503,4NEVK@976,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain MAG.T22.3_02925 290317.Cpha266_2196 5.7e-13 79.7 Bacteria Bacteria COG4634@1,COG4634@2 NA|NA|NA MAG.T22.3_02926 1128427.KB904821_gene1111 4.8e-21 106.7 Oscillatoriales Bacteria 1G7SB@1117,1HCGW@1150,COG2442@1,COG2442@2 NA|NA|NA S Protein of unknown function (DUF433) MAG.T22.3_02927 1239962.C943_01613 5.4e-107 393.7 Cytophagia ko:K03088 ko00000,ko03021 Bacteria 47JCE@768503,4NIRG@976,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T22.3_02928 1239962.C943_01614 2.6e-179 634.8 Cytophagia ko:K20541 ko00000,ko02000 4.D.3.1.6 Bacteria 47JZE@768503,4NESG@976,COG1215@1,COG1215@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T22.3_02929 1239962.C943_01616 5.8e-216 756.5 Cytophagia tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 R03789,R10209 RC00063 ko00000,ko01000,ko03016 Bacteria 47JEY@768503,4NE15@976,COG0343@1,COG0343@2 NA|NA|NA J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) MAG.T22.3_02930 1239962.C943_01617 1.5e-192 678.7 Cytophagia lptG GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0033036,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K11720 ko02010,map02010 M00320 ko00000,ko00001,ko00002,ko02000 1.B.42.1 iSSON_1240.SSON_4447 Bacteria 47JHT@768503,4NF8Y@976,COG0795@1,COG0795@2 NA|NA|NA S Permease YjgP YjgQ family MAG.T22.3_02931 1239962.C943_01618 1.5e-148 532.3 Cytophagia Bacteria 47JNH@768503,4NE8D@976,COG0697@1,COG0697@2 NA|NA|NA EG PFAM EamA-like transporter family MAG.T22.3_02932 1239962.C943_01619 2.2e-45 188.3 Bacteroidetes ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 4NUF5@976,COG4654@1,COG4654@2 NA|NA|NA C Cytochrome c MAG.T22.3_02933 1239962.C943_01621 0.0 1874.8 Cytophagia carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0661 Bacteria 47ME8@768503,4NEQ0@976,COG0458@1,COG0458@2 NA|NA|NA EF PFAM Carbamoyl-phosphate synthase L chain, ATP binding MAG.T22.3_02934 1239962.C943_01622 3e-35 154.1 Cytophagia Bacteria 2EHT5@1,33BIV@2,47RUH@768503,4NXXG@976 NA|NA|NA S Domain of unknown function (DUF4834) MAG.T22.3_02935 1239962.C943_01623 0.0 1638.2 Cytophagia ko:K14054 ko00000 Bacteria 47KZ0@768503,4NEJA@976,COG2866@1,COG2866@2 NA|NA|NA E PFAM Zinc carboxypeptidase MAG.T22.3_02936 1239962.C943_01625 0.0 1178.7 Cytophagia glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iAF987.Gmet_1487 Bacteria 47KVG@768503,4NE8Q@976,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source MAG.T22.3_02937 1239962.C943_01626 9.7e-234 815.8 Cytophagia Bacteria 2DBTI@1,2ZAYJ@2,47M3A@768503,4NJ34@976 NA|NA|NA MAG.T22.3_02938 1239962.C943_01627 2.1e-151 541.6 Cytophagia glgA GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 GT5 Bacteria 47KUD@768503,4NFP8@976,COG0297@1,COG0297@2 NA|NA|NA G PFAM Starch synthase catalytic domain MAG.T22.3_02939 1239962.C943_01628 2.2e-134 485.0 Cytophagia panC GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25,6.3.2.1 ko:K01918,ko:K13799 ko00240,ko00410,ko00770,ko01100,ko01110,map00240,map00410,map00770,map01100,map01110 M00052,M00119 R00158,R00512,R01665,R02473 RC00002,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 Bacteria 47MNB@768503,4NFT9@976,COG0414@1,COG0414@2 NA|NA|NA H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate MAG.T22.3_02940 1239962.C943_01629 8.4e-57 226.1 Cytophagia panD 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 47QA8@768503,4NQ42@976,COG0853@1,COG0853@2 NA|NA|NA H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine MAG.T22.3_02941 1239962.C943_01630 2.5e-167 594.7 Cytophagia ko:K07027 ko00000,ko02000 4.D.2 Bacteria 47JZY@768503,4NGPD@976,COG0392@1,COG0392@2 NA|NA|NA S PFAM Uncharacterised protein family (UPF0104) MAG.T22.3_02942 1239962.C943_01631 5.1e-114 417.2 Cytophagia yugP ko:K06973 ko00000 Bacteria 47MH4@768503,4NDWG@976,COG2738@1,COG2738@2 NA|NA|NA S PFAM Peptidase, membrane zinc metallopeptidase MAG.T22.3_02943 1239962.C943_01632 8.5e-207 726.1 Cytophagia bcd 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 Bacteria 47JZA@768503,4NEHA@976,COG1960@1,COG1960@2 NA|NA|NA I acyl-CoA dehydrogenase MAG.T22.3_02944 1239962.C943_01633 5.7e-169 600.1 Cytophagia Bacteria 47MM1@768503,4NFHF@976,COG2207@1,COG2207@2 NA|NA|NA K Transcriptional regulator, AraC family MAG.T22.3_02945 1189612.A33Q_3177 1e-12 80.1 Cytophagia Bacteria 2E55B@1,32ZY9@2,47WUD@768503,4NVWQ@976 NA|NA|NA MAG.T22.3_02946 1239962.C943_01635 0.0 1593.9 Cytophagia Bacteria 47JB2@768503,4PKVH@976,COG1629@1,COG1629@2 NA|NA|NA P Carboxypeptidase regulatory-like domain MAG.T22.3_02947 1239962.C943_01637 4.1e-92 344.4 Cytophagia Bacteria 47QQU@768503,4NRXE@976,COG1846@1,COG1846@2 NA|NA|NA K Winged helix DNA-binding domain MAG.T22.3_02949 1239962.C943_03490 2.4e-158 564.7 Bacteroidetes ispH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.4,2.7.4.25 ko:K00945,ko:K02945,ko:K03527 ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010 M00052,M00096,M00178 R00158,R00512,R01665,R05884,R08210 RC00002,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 iECIAI1_1343.ECIAI1_0030,iECW_1372.ECW_m0028,iEKO11_1354.EKO11_3884,iEcHS_1320.EcHS_A0031,iEcolC_1368.EcolC_3626,iIT341.HP0400,iLJ478.TM1444,iPC815.YPO0477,iSFV_1184.SFV_0023,iSF_1195.SF0026,iSFxv_1172.SFxv_0027,iS_1188.S0028,iWFL_1372.ECW_m0028,iYL1228.KPN_00024 Bacteria 4NDUX@976,COG0761@1,COG0761@2 NA|NA|NA IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis MAG.T22.3_02950 1239962.C943_03491 1.2e-126 459.1 Cytophagia Bacteria 2ZZTD@2,47Q57@768503,4NNMY@976,arCOG05416@1 NA|NA|NA S lycopene cyclase MAG.T22.3_02951 1239962.C943_03492 4e-153 547.4 Cytophagia crtB GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99 ko:K00801,ko:K02291,ko:K10208 ko00100,ko00906,ko00909,ko01062,ko01100,ko01110,ko01130,map00100,map00906,map00909,map01062,map01100,map01110,map01130 M00097 R00702,R02065,R02872,R04218,R06223,R07270,R07652,R09793,R10177 RC00362,RC00796,RC01101,RC02839,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 47J9F@768503,4NEIK@976,COG1562@1,COG1562@2 NA|NA|NA I PFAM Squalene phytoene synthase MAG.T22.3_02952 1239962.C943_03493 2.6e-280 970.7 Cytophagia crtI 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 ko:K10027,ko:K20611 ko00906,ko01100,ko01110,map00906,map01100,map01110 R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 Bacteria 47JMY@768503,4NF7K@976,COG1233@1,COG1233@2 NA|NA|NA Q TIGRFAM phytoene desaturase MAG.T22.3_02953 1239962.C943_03494 2.8e-93 347.8 Cytophagia sigR_3 ko:K03088 ko00000,ko03021 Bacteria 47KPZ@768503,4NMM3@976,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T22.3_02954 1239962.C943_03495 1.7e-162 578.6 Cytophagia ycgE ko:K21089,ko:K21972,ko:K22491 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 47K07@768503,4NERC@976,COG0789@1,COG0789@2,COG5012@1,COG5012@2 NA|NA|NA K PFAM MerR family regulatory protein MAG.T22.3_02955 1239962.C943_03496 7.1e-64 250.0 Cytophagia crtZ 1.14.15.24 ko:K15746 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00372 R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747 RC00478,RC00704,RC02629 ko00000,ko00001,ko00002,ko01000 Bacteria 47PV8@768503,4NMA9@976,COG3000@1,COG3000@2 NA|NA|NA I PFAM Fatty acid hydroxylase MAG.T22.3_02956 1239962.C943_03497 2.3e-122 444.9 Cytophagia cruF 5.5.1.19 ko:K22502 ko00906,map00906 R03824,R05341 RC01004 ko00000,ko00001,ko01000 Bacteria 47QH8@768503,4NQR7@976,COG2324@1,COG2324@2 NA|NA|NA S Carotenoid biosynthesis protein MAG.T22.3_02957 1239962.C943_03498 4.3e-49 200.3 Cytophagia Bacteria 2C9BK@1,32RP1@2,47RVQ@768503,4NSPA@976 NA|NA|NA S Domain of unknown function (DUF4286) MAG.T22.3_02958 1239962.C943_03499 1.1e-104 386.0 Cytophagia tag 3.2.2.20 ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 47PXB@768503,4NGRC@976,COG2818@1,COG2818@2 NA|NA|NA L PFAM methyladenine glycosylase MAG.T22.3_02960 1239962.C943_03501 4.7e-109 400.6 Cytophagia Bacteria 2DS2Z@1,33EAC@2,47T75@768503,4P46N@976 NA|NA|NA MAG.T22.3_02961 1239962.C943_03502 4.3e-177 627.1 Cytophagia Bacteria 28K2C@1,2Z9RQ@2,47N7B@768503,4NJP3@976 NA|NA|NA MAG.T22.3_02962 1239962.C943_03503 3.7e-298 1030.0 Cytophagia Bacteria 47M29@768503,4NGYP@976,COG0671@1,COG0671@2 NA|NA|NA I PAP2 superfamily MAG.T22.3_02963 1239962.C943_03505 6e-136 490.7 Cytophagia Bacteria 47M83@768503,4NHD5@976,COG2128@1,COG2128@2 NA|NA|NA S Protein of unknown function (DUF3179) MAG.T22.3_02964 760192.Halhy_0028 4.4e-60 237.7 Sphingobacteriia Bacteria 1IXMN@117747,4NMGS@976,COG2128@1,COG2128@2 NA|NA|NA S Carboxymuconolactone decarboxylase family MAG.T22.3_02965 1123278.KB893418_gene4054 0.0 1104.0 Cytophagia Bacteria 47Y1Q@768503,4NDX3@976,COG1629@1,COG4771@2 NA|NA|NA P Carboxypeptidase regulatory-like domain MAG.T22.3_02966 1123248.KB893333_gene2814 4.8e-78 298.5 Sphingobacteriia ko:K05548,ko:K08195 ko00000,ko02000 2.A.1.15 Bacteria 1IV9Q@117747,4NEY4@976,COG0477@1,COG2814@2 NA|NA|NA EGP Sugar (and other) transporter MAG.T22.3_02967 1123248.KB893333_gene2813 5.9e-49 200.7 Sphingobacteriia Bacteria 1IT75@117747,4NNYF@976,COG2128@1,COG2128@2 NA|NA|NA S Carboxymuconolactone decarboxylase family MAG.T22.3_02968 760192.Halhy_0024 1.6e-57 229.2 Sphingobacteriia Bacteria 1IWPA@117747,4NNHK@976,COG2128@1,COG2128@2 NA|NA|NA S Carboxymuconolactone decarboxylase family MAG.T22.3_02969 1239962.C943_03506 7.7e-286 989.2 Cytophagia cstA ko:K06200 ko00000 Bacteria 47KHG@768503,4NFPD@976,COG1966@1,COG1966@2 NA|NA|NA T Carbon starvation protein CstA MAG.T22.3_02970 1239962.C943_03508 2.7e-157 561.2 Cytophagia accD GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iJN678.accD,iPC815.YPO2768,iUTI89_1310.UTI89_C2601 Bacteria 47JX2@768503,4NFMH@976,COG0777@1,COG0777@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA MAG.T22.3_02971 1239962.C943_03509 3e-256 890.6 Cytophagia nqrF 1.6.5.8 ko:K00351 ko00000,ko01000 Bacteria 47NPF@768503,4NFKC@976,COG2871@1,COG2871@2 NA|NA|NA C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway MAG.T22.3_02972 1239962.C943_03510 2.1e-221 774.6 Cytophagia 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 Bacteria 47JES@768503,4NE5W@976,COG0010@1,COG0010@2 NA|NA|NA E Belongs to the arginase family MAG.T22.3_02973 1239962.C943_03511 1.1e-39 168.7 Cytophagia Bacteria 47R83@768503,4NSAM@976,COG4892@1,COG4892@2 NA|NA|NA S PFAM Cytochrome b5-like Heme Steroid binding domain MAG.T22.3_02974 1239962.C943_03512 1.4e-161 575.5 Cytophagia gspK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047931 2.7.1.8 ko:K18676 ko00520,ko01100,map00520,map01100 R01961 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 47MGQ@768503,4NEV4@976,COG2971@1,COG2971@2 NA|NA|NA G N-acetylglucosamine kinase MAG.T22.3_02975 1239962.C943_03513 7.1e-147 526.6 Cytophagia murQ 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 R08555 RC00397,RC00746 ko00000,ko00001,ko01000 Bacteria 47K6T@768503,4NEPY@976,COG2103@1,COG2103@2 NA|NA|NA G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate MAG.T22.3_02976 1239962.C943_03514 3.8e-180 638.3 Cytophagia rluB 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 ko00000,ko01000,ko03009 Bacteria 47JIE@768503,4NEE1@976,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family MAG.T22.3_02977 1123057.P872_00060 6.4e-41 174.1 Cytophagia Bacteria 2DNBH@1,32WMM@2,47REN@768503,4NUG2@976 NA|NA|NA MAG.T22.3_02978 1239962.C943_03517 4.7e-74 283.9 Cytophagia Bacteria 2B4UZ@1,31XMJ@2,47QGM@768503,4NR0F@976 NA|NA|NA S Domain of unknown function (DUF4252) MAG.T22.3_02979 1239962.C943_03518 1.2e-91 342.4 Cytophagia Bacteria 2CC1H@1,33P9C@2,47RW7@768503,4NYJE@976 NA|NA|NA S Domain of unknown function (DUF4252) MAG.T22.3_02980 1239962.C943_03519 6.4e-70 270.0 Cytophagia cpeZ ko:K05386 ko00196,ko01100,map00196,map01100 ko00000,ko00001,ko00194 Bacteria 47VAW@768503,4PB6E@976,COG1413@1,COG1413@2 NA|NA|NA C lyase activity MAG.T22.3_02981 1239962.C943_03520 3e-72 277.7 Cytophagia ko:K03088 ko00000,ko03021 Bacteria 47Q3K@768503,4NSED@976,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 MAG.T22.3_02983 688270.Celal_3310 9.2e-33 146.7 Cellulophaga ko:K06872 ko00000 Bacteria 1F9JM@104264,1I3XE@117743,4NS9C@976,COG1512@1,COG1512@2 NA|NA|NA S COGs COG1512 Beta-propeller domains of methanol dehydrogenase type MAG.T22.3_02984 1405.DJ92_201 1.5e-18 99.8 Bacillus Bacteria 1VX7K@1239,1ZJ5Q@1386,2EAD4@1,334H0@2,4HX6A@91061 NA|NA|NA S SUKH-4 immunity protein MAG.T22.3_02985 1121898.Q766_04220 1.6e-34 152.5 Flavobacteriia ko:K07066 ko00000 Bacteria 1IA55@117743,4NSZC@976,COG2405@1,COG2405@2 NA|NA|NA S Domain of unknown function (DUF3368) MAG.T22.3_02986 865937.Gilli_1099 6.7e-23 112.8 Bacteroidetes Bacteria 4NYD2@976,COG2886@1,COG2886@2 NA|NA|NA S Uncharacterised protein family (UPF0175) MAG.T22.3_02988 1239962.C943_03523 1.6e-68 265.4 Bacteria Bacteria COG1848@1,COG1848@2 NA|NA|NA G Toxic component of a toxin-antitoxin (TA) module. An RNase MAG.T22.3_02989 1189612.A33Q_1536 6e-17 93.2 Cytophagia Bacteria 2DMNP@1,32SQ4@2,47WCH@768503,4NT2A@976 NA|NA|NA MAG.T22.3_02991 1239962.C943_03525 6.4e-246 856.3 Cytophagia Bacteria 47JED@768503,4NF3K@976,COG1150@1,COG1150@2 NA|NA|NA C 4Fe-4S dicluster domain MAG.T22.3_02992 1239962.C943_03526 3.3e-149 534.3 Cytophagia Bacteria 47KRT@768503,4NDZS@976,COG0247@1,COG0247@2 NA|NA|NA C PFAM Cysteine-rich domain MAG.T22.3_02993 1239962.C943_03527 3.9e-84 317.4 Cytophagia Bacteria 28NRS@1,2ZBQZ@2,47RCF@768503,4NMM5@976 NA|NA|NA MAG.T22.3_02994 1239962.C943_03528 0.0 1243.4 Cytophagia pal ko:K03640 ko00000,ko02000 2.C.1.2 Bacteria 47JJM@768503,4NE6G@976,COG0457@1,COG0457@2,COG0823@1,COG0823@2,COG2885@1,COG2885@2 NA|NA|NA MU Belongs to the ompA family MAG.T22.3_02995 1239962.C943_03529 1.7e-73 282.0 Cytophagia Bacteria 2CM2H@1,32SDI@2,47R71@768503,4NSAF@976 NA|NA|NA S Putative lumazine-binding MAG.T22.3_02996 1239962.C943_03530 1.7e-101 375.6 Cytophagia ko:K03973 ko00000,ko02048,ko03000 Bacteria 47S0P@768503,4PKYR@976,COG1983@1,COG1983@2 NA|NA|NA KT Putative auto-transporter adhesin, head GIN domain MAG.T22.3_02997 1239962.C943_03531 1.3e-117 429.1 Cytophagia Bacteria 47YGH@768503,4PM6R@976,COG4221@1,COG4221@2 NA|NA|NA S NAD dependent epimerase/dehydratase family MAG.T22.3_02998 1239962.C943_03532 9e-148 529.6 Cytophagia ko:K22044 ko00000,ko02000 1.A.23.3 Bacteria 47PQG@768503,4NNJC@976,COG0668@1,COG0668@2 NA|NA|NA M mechanosensitive ion channel MAG.T22.3_02999 1239962.C943_03533 6.9e-56 223.0 Cytophagia ybaZ GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 ko:K00567,ko:K07443 ko00000,ko01000,ko03400 Bacteria 47R4H@768503,4NQ34@976,COG3695@1,COG3695@2 NA|NA|NA L PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain MAG.T22.3_03000 1239962.C943_03534 1.9e-59 235.0 Cytophagia ropB Bacteria 47QWV@768503,4NQSM@976,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins MAG.T22.3_03001 1239962.C943_03535 2.6e-261 907.5 Cytophagia Bacteria 47KNW@768503,4NEF3@976,COG0591@1,COG0591@2 NA|NA|NA E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family MAG.T22.3_03002 1239962.C943_03536 8.4e-42 176.0 Cytophagia clpS GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 ko:K06891 ko00000 Bacteria 47R8K@768503,4NS8R@976,COG2127@1,COG2127@2 NA|NA|NA S PFAM ATP-dependent Clp protease adaptor protein ClpS MAG.T22.3_03003 1239962.C943_03537 1e-108 399.4 Cytophagia recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 47JZK@768503,4NEWI@976,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO MAG.T22.3_03005 1239962.C943_03538 2.3e-101 375.6 Cytophagia Bacteria 47MIA@768503,4NJCC@976,COG3595@1,COG3595@2 NA|NA|NA MAG.T22.3_03007 1121859.KB890739_gene2695 6.6e-81 307.4 Cytophagia Bacteria 47QTA@768503,4NRJJ@976,COG4185@1,COG4185@2 NA|NA|NA S zeta toxin MAG.T22.3_03008 1123057.P872_12670 6.7e-24 117.9 Cytophagia Bacteria 2C9V5@1,2Z8F9@2,47S8V@768503,4NG2N@976 NA|NA|NA MAG.T22.3_03009 866536.Belba_0870 8.1e-198 696.4 Cytophagia hpaIIM 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 47MCJ@768503,4NG9A@976,COG0270@1,COG0270@2 NA|NA|NA H PFAM C-5 cytosine-specific DNA methylase MAG.T22.3_03011 1121859.KB890758_gene1823 1.4e-139 502.7 Cytophagia hpaIIR 3.1.21.4 ko:K01155 ko00000,ko01000,ko02048 Bacteria 28HT5@1,2Z803@2,47UZY@768503,4NQQY@976 NA|NA|NA L HpaII restriction endonuclease MAG.T22.3_03012 1288963.ADIS_4343 4.3e-100 370.9 Bacteroidetes Bacteria 4NT7F@976,COG3440@1,COG3440@2 NA|NA|NA V HNH endonuclease MAG.T22.3_03014 1392490.JHZX01000001_gene1390 6.9e-09 66.2 Flavobacteriia Bacteria 1I6I7@117743,2EQB7@1,33HXB@2,4NZPJ@976 NA|NA|NA MAG.T22.3_03016 1239962.C943_03560 3e-166 591.3 Cytophagia Bacteria 28I9R@1,2Z8CE@2,47XS5@768503,4NNRK@976 NA|NA|NA S Lipid A 3-O-deacylase (PagL) MAG.T22.3_03017 1239962.C943_03561 3.9e-117 427.6 Cytophagia Bacteria 47XVE@768503,4NW0T@976,COG3595@1,COG3595@2 NA|NA|NA S Putative auto-transporter adhesin, head GIN domain MAG.T22.3_03018 1239962.C943_03562 0.0 1662.9 Cytophagia ko:K14054 ko00000 Bacteria 47KZ0@768503,4NEJA@976,COG2866@1,COG2866@2 NA|NA|NA E PFAM Zinc carboxypeptidase MAG.T22.3_03019 1239962.C943_03564 1.7e-254 884.8 Cytophagia Bacteria 47XBR@768503,4NISN@976,COG1228@1,COG1228@2 NA|NA|NA Q Amidohydrolase family MAG.T22.3_03020 1239962.C943_03565 2.4e-256 891.0 Cytophagia radA ko:K04485 ko00000,ko03400 Bacteria 47K0I@768503,4NEYA@976,COG1066@1,COG1066@2 NA|NA|NA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function MAG.T22.3_03021 1239962.C943_03566 5.3e-190 670.2 Cytophagia Bacteria 47Q52@768503,4NME8@976,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase MAG.T22.3_03022 1239962.C943_03567 2.2e-185 654.8 Cytophagia ddl 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 47M8U@768503,4NE9P@976,COG1181@1,COG1181@2 NA|NA|NA F Belongs to the D-alanine--D-alanine ligase family MAG.T22.3_03023 1239962.C943_03579 4e-234 817.0 Cytophagia metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 Bacteria 47JW7@768503,4NG7Y@976,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme MAG.T22.3_03024 1239962.C943_03580 1.2e-211 742.3 Cytophagia purM 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 Bacteria 47JG0@768503,4NE4E@976,COG0150@1,COG0150@2 NA|NA|NA F PFAM AIR synthase related protein MAG.T22.3_03025 1239962.C943_03581 5e-230 803.5 Cytophagia 3.5.1.23 ko:K12349 ko00600,ko01100,ko04071,map00600,map01100,map04071 M00099 R01494 RC00064,RC00328 ko00000,ko00001,ko00002,ko01000 Bacteria 47JVE@768503,4NGDG@976,COG3356@1,COG3356@2 NA|NA|NA S Neutral/alkaline non-lysosomal ceramidase, N-terminal MAG.T22.3_03026 1123057.P872_17920 1.6e-34 153.3 Cytophagia Bacteria 2E39A@1,32Y8X@2,47SFE@768503,4NWB4@976 NA|NA|NA MAG.T22.3_03027 1239962.C943_03583 7.7e-109 399.8 Cytophagia 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 47Q5Q@768503,4NP89@976,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase MAG.T22.3_03028 1239962.C943_03584 0.0 1502.6 Cytophagia 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 R06620 RC00066 ko00000,ko00001,ko01000 Bacteria 47TQS@768503,4NH58@976,COG2010@1,COG2010@2,COG4993@1,COG4993@2 NA|NA|NA CG PQQ enzyme repeat MAG.T22.3_03029 1239962.C943_03586 1e-221 775.8 Cytophagia 3.4.13.22 ko:K08641,ko:K11312 ko01502,ko02020,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Bacteria 47UCJ@768503,4NHX8@976,COG0662@1,COG0662@2,COG3837@1,COG3837@2 NA|NA|NA G Cupin domain MAG.T22.3_03030 1239962.C943_03587 2.6e-169 601.3 Cytophagia Bacteria 47JU7@768503,4NF3M@976,COG0684@1,COG0684@2 NA|NA|NA H Aldolase/RraA MAG.T22.3_03031 1239962.C943_03055 2.2e-137 495.0 Cytophagia plsC 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 47JI7@768503,4NG5R@976,COG0204@1,COG0204@2 NA|NA|NA I TIGRFAM 1-acyl-sn-glycerol-3-phosphate acyltransferases MAG.T22.3_03032 1239962.C943_03056 4e-65 253.8 Cytophagia glbO GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 ko:K06886 ko00000 Bacteria 47RRK@768503,4NTJR@976,COG2346@1,COG2346@2 NA|NA|NA S Bacterial-like globin MAG.T22.3_03033 1305737.JAFX01000001_gene3416 1.8e-56 225.3 Cytophagia ko:K07491 ko00000 Bacteria 47PWF@768503,4NNQJ@976,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like MAG.T22.3_03034 1239962.C943_03060 7.5e-106 389.8 Cytophagia Bacteria 47VGK@768503,4PB9A@976,COG3637@1,COG3637@2 NA|NA|NA M Outer membrane protein beta-barrel domain MAG.T22.3_03035 1239962.C943_03061 1.7e-142 511.9 Cytophagia 2.1.1.72 ko:K03556,ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03000,ko03032,ko03400 Bacteria 47UBP@768503,4NPSQ@976,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family MAG.T22.3_03038 1358423.N180_08675 8.2e-57 226.9 Sphingobacteriia lacA Bacteria 1IWYX@117747,4NH27@976,COG0110@1,COG0110@2 NA|NA|NA S Hexapeptide repeat of succinyl-transferase MAG.T22.3_03039 1239962.C943_04299 6.4e-210 736.5 Cytophagia metK-2 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 Bacteria 47TNF@768503,4P07E@976,COG1812@1,COG1812@2 NA|NA|NA E S-adenosylmethionine synthetase (AdoMet synthetase) MAG.T22.3_03040 1239962.C943_04300 7.4e-130 469.9 Cytophagia Bacteria 2C2AI@1,32RA3@2,47QSS@768503,4NQ4M@976 NA|NA|NA MAG.T22.3_03041 929562.Emtol_2272 4e-59 234.6 Cytophagia Bacteria 47QTJ@768503,4NJRX@976,COG0664@1,COG0664@2 NA|NA|NA T Cyclic nucleotide-binding domain MAG.T22.3_03042 929562.Emtol_2271 4.8e-66 257.3 Cytophagia Bacteria 47QXV@768503,4NN7V@976,COG2318@1,COG2318@2 NA|NA|NA S DinB family MAG.T22.3_03043 1168034.FH5T_18105 1.2e-97 362.8 Bacteroidetes ko:K09190 ko00000 Bacteria 4NHNG@976,COG3403@1,COG3403@2 NA|NA|NA S YqcI/YcgG family MAG.T22.3_03044 1123057.P872_16705 6.7e-95 354.0 Cytophagia Bacteria 47QR9@768503,4PKY0@976,COG1073@1,COG1073@2 NA|NA|NA S Alpha/beta hydrolase family MAG.T22.3_03045 1131812.JQMS01000001_gene678 1.3e-124 453.0 Bacteroidetes ko:K01250 ko00000,ko01000 Bacteria 4NJ4J@976,COG1957@1,COG1957@2 NA|NA|NA F Inosine-uridine preferring nucleoside hydrolase MAG.T22.3_03046 1239962.C943_04301 5.5e-170 603.6 Cytophagia Bacteria 47JHN@768503,4NDYY@976,COG2207@1,COG2207@2 NA|NA|NA K PFAM helix-turn-helix- domain containing protein AraC type MAG.T22.3_03047 866536.Belba_2570 1.1e-166 592.8 Cytophagia Bacteria 47RGA@768503,4NFSV@976,COG1075@1,COG1075@2 NA|NA|NA S Alpha/beta hydrolase family MAG.T22.3_03048 1239962.C943_04302 8.3e-65 253.1 Cytophagia Bacteria 47UV3@768503,4NNR7@976,COG1917@1,COG1917@2 NA|NA|NA S Domain of unknown function (DUF4440) MAG.T22.3_03049 1120965.AUBV01000010_gene2769 1.6e-63 248.8 Bacteroidetes Bacteria 4NR0K@976,COG1917@1,COG1917@2 NA|NA|NA S Domain of unknown function (DUF4440) MAG.T22.3_03050 362418.IW19_22200 1.1e-67 263.1 Flavobacterium Bacteria 1I18K@117743,2NTPK@237,4NNTA@976,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin MAG.T22.3_03051 1168034.FH5T_18160 9e-118 429.9 Bacteroidia yvgN 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 2FMAF@200643,4NFTA@976,COG0656@1,COG0656@2 NA|NA|NA S aldo keto reductase family MAG.T22.3_03052 760192.Halhy_0712 9.4e-228 796.2 Sphingobacteriia GO:0001503,GO:0001505,GO:0001507,GO:0001540,GO:0001649,GO:0002076,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0003990,GO:0004104,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005604,GO:0005605,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005794,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006581,GO:0006629,GO:0006644,GO:0006650,GO:0006656,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007155,GO:0007267,GO:0007268,GO:0007271,GO:0007275,GO:0007399,GO:0007416,GO:0007517,GO:0008144,GO:0008150,GO:0008152,GO:0008283,GO:0008291,GO:0008610,GO:0008654,GO:0009056,GO:0009058,GO:0009059,GO:0009611,GO:0009987,GO:0010646,GO:0010648,GO:0010817,GO:0012505,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0017144,GO:0017171,GO:0019538,GO:0019637,GO:0022607,GO:0022610,GO:0023051,GO:0023052,GO:0023057,GO:0030154,GO:0031012,GO:0032222,GO:0032223,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0033218,GO:0034641,GO:0034645,GO:0042133,GO:0042135,GO:0042136,GO:0042165,GO:0042166,GO:0042277,GO:0042445,GO:0042447,GO:0042562,GO:0042737,GO:0042802,GO:0042803,GO:0042982,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043236,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044420,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045017,GO:0045202,GO:0046470,GO:0046474,GO:0046483,GO:0046486,GO:0046983,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048731,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050794,GO:0050804,GO:0050805,GO:0050808,GO:0050840,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0052689,GO:0061061,GO:0062023,GO:0065007,GO:0065008,GO:0070201,GO:0070405,GO:0071704,GO:0071840,GO:0071944,GO:0090087,GO:0090304,GO:0090407,GO:0097164,GO:0098916,GO:0099177,GO:0099536,GO:0099537,GO:1900619,GO:1901360,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951 ko:K03929 ko00000,ko01000 CE10 Bacteria 1IQ9M@117747,4NF5N@976,COG2272@1,COG2272@2 NA|NA|NA I Belongs to the type-B carboxylesterase lipase family MAG.T22.3_03053 504472.Slin_2757 1.8e-119 436.0 Cytophagia Bacteria 47JZH@768503,4NEB0@976,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family MAG.T22.3_03054 1120965.AUBV01000010_gene2768 0.0 1321.6 Cytophagia 1.3.99.16 ko:K07303 ko00000,ko01000 Bacteria 47KU3@768503,4NFFU@976,COG1529@1,COG1529@2 NA|NA|NA C Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL MAG.T22.3_03055 1239962.C943_04303 2.4e-80 304.7 Cytophagia 1.3.99.16 ko:K07302,ko:K07303 ko00000,ko01000 Bacteria 47PA8@768503,4NM72@976,COG2080@1,COG2080@2 NA|NA|NA C 2Fe-2S -binding domain MAG.T22.3_03056 1123057.P872_16670 0.0 1228.4 Cytophagia 1.3.99.16 ko:K07303 ko00000,ko01000 Bacteria 47KPV@768503,4NFFU@976,COG1529@1,COG1529@2 NA|NA|NA C Aldehyde oxidase and xanthine dehydrogenase molybdopterin binding MAG.T22.3_03057 1189612.A33Q_4691 1.4e-35 156.4 Cytophagia Bacteria 2CC4T@1,33WVG@2,47V16@768503,4P3V6@976 NA|NA|NA MAG.T22.3_03059 1189612.A33Q_2247 9.5e-73 280.4 Bacteroidetes Bacteria 4NTY2@976,COG2250@1,COG2250@2 NA|NA|NA S HEPN domain MAG.T22.3_03063 1416760.AYMS01000175_gene1456 2.1e-43 181.8 Myroides Bacteria 1I2EK@117743,47J8F@76831,4NP3E@976,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix domain MAG.T22.3_03064 1288963.ADIS_2283 6e-107 394.4 Bacteroidetes Bacteria 4NMYC@976,COG2856@1,COG2856@2 NA|NA|NA E Zn peptidase MAG.T22.3_03065 1121912.AUHD01000008_gene37 8.4e-41 173.7 Flavobacteriia Bacteria 1IAQ9@117743,2EJ0S@1,33CRY@2,4NXHH@976 NA|NA|NA S Domain of unknown function (DUF4411) MAG.T22.3_03069 886377.Murru_3188 4.9e-38 166.0 Flavobacteriia Bacteria 1I150@117743,28M16@1,2ZAG1@2,4NIDU@976 NA|NA|NA MAG.T22.3_03070 1305737.JAFX01000001_gene179 0.0 1498.4 Cytophagia res 3.1.21.5 ko:K01156 ko00000,ko01000,ko02048 Bacteria 47NJ5@768503,4NGM0@976,COG3587@1,COG3587@2 NA|NA|NA V Type III restriction enzyme, res subunit MAG.T22.3_03071 221027.JO40_06010 1.4e-148 532.7 Spirochaetes 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2J707@203691,COG2865@1,COG2865@2 NA|NA|NA K DNA helicase MAG.T22.3_03072 880072.Desac_0721 4.4e-198 698.4 Deltaproteobacteria ko:K18491 ko04550,map04550 ko00000,ko00001,ko03000 Bacteria 1PRIC@1224,2WPPR@28221,42MSM@68525,COG0613@1,COG0613@2,COG1196@1,COG1196@2 NA|NA|NA D PHP domain protein MAG.T22.3_03073 1305737.JAFX01000001_gene176 1.1e-233 816.2 Cytophagia mod 2.1.1.72 ko:K07316 ko00000,ko01000,ko02048 Bacteria 47K7W@768503,4NFKE@976,COG2189@1,COG2189@2 NA|NA|NA L DNA methylase MAG.T22.3_03075 1239962.C943_04308 1.6e-88 332.4 Cytophagia Bacteria 2E9WF@1,33426@2,47WZZ@768503,4P894@976 NA|NA|NA MAG.T22.3_03076 1239962.C943_04309 0.0 1101.3 Bacteria Bacteria 2ESRG@1,33K9V@2 NA|NA|NA MAG.T22.3_03077 1239962.C943_04310 6.2e-76 290.4 Bacteroidetes ko:K09164 ko00000 Bacteria 4NNWJ@976,COG3358@1,COG3358@2 NA|NA|NA S COGs COG3358 conserved MAG.T22.3_03079 1239962.C943_04311 3.7e-91 340.9 Bacteroidetes Bacteria 2CEM2@1,33F1K@2,4NYR3@976 NA|NA|NA MAG.T22.3_03080 1239962.C943_04312 4.3e-250 870.2 Cytophagia puo 1.4.3.10,1.4.3.4 ko:K00274,ko:K03343 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R01151,R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 Bacteria 47MSR@768503,4NGST@976,COG1231@1,COG1231@2 NA|NA|NA E Flavin containing amine oxidoreductase MAG.T22.3_03082 1239962.C943_04315 1.1e-104 386.0 Cytophagia ko:K06196 ko00000,ko02000 5.A.1.2 Bacteria 47QR6@768503,4NI00@976,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin-like MAG.T22.3_03083 1239962.C943_04317 7.6e-98 363.2 Bacteria ko:K06196 ko00000,ko02000 5.A.1.2 Bacteria COG0526@1,COG0526@2 NA|NA|NA CO cell redox homeostasis MAG.T22.3_03084 1239962.C943_04319 2.9e-108 397.9 Bacteroidetes Bacteria 2C7HJ@1,32NAU@2,4NQER@976 NA|NA|NA MAG.T22.3_03085 1239962.C943_04321 0.0 1393.3 Cytophagia yhgF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 ko:K06959 ko00000 Bacteria 47MKQ@768503,4NETD@976,COG2183@1,COG2183@2 NA|NA|NA K TIGRFAM competence protein ComEA helix-hairpin-helix repeat region MAG.T22.3_03087 1239962.C943_04324 5.3e-40 169.9 Cytophagia Bacteria 2DWUG@1,341Y5@2,47VJ4@768503,4P4Q3@976 NA|NA|NA MAG.T22.3_03088 1239962.C943_04325 8.2e-137 493.0 Cytophagia Bacteria 47Y54@768503,4NDUW@976,COG1476@1,COG1476@2,COG2932@1,COG2932@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins MAG.T22.3_03089 1239962.C943_04326 6.6e-202 709.9 Bacteroidetes 6.3.2.47 ko:K22114 ko00000,ko01000 Bacteria 4PM91@976,COG0151@1,COG0151@2 NA|NA|NA F ATP-grasp domain MAG.T22.3_03090 1239962.C943_04327 2.4e-53 214.9 Cytophagia Bacteria 47S7U@768503,4NUS8@976,COG4704@1,COG4704@2 NA|NA|NA S protein conserved in bacteria MAG.T22.3_03091 1239962.C943_04328 3.5e-162 577.8 Cytophagia menE 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 47KUG@768503,4NEXK@976,COG0318@1,COG0318@2 NA|NA|NA IQ Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II MAG.T22.3_03092 1239962.C943_04329 1.8e-158 565.1 Cytophagia menB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071890,GO:0071944,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07263 RC01923 ko00000,ko00001,ko00002,ko01000 Bacteria 47JYS@768503,4NDXT@976,COG0447@1,COG0447@2 NA|NA|NA H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) MAG.T22.3_03093 153721.MYP_4608 1.1e-70 273.1 Cytophagia yijF ko:K09974 ko00000 Bacteria 47TQN@768503,4NM46@976,COG3738@1,COG3738@2 NA|NA|NA S Domain of unknown function (DUF1287) MAG.T22.3_03094 1239962.C943_04330 1.7e-148 531.9 Cytophagia ytpA GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010941,GO:0010942,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0030312,GO:0031341,GO:0031343,GO:0031640,GO:0035821,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0046486,GO:0046503,GO:0047372,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051709,GO:0051712,GO:0051817,GO:0051818,GO:0051883,GO:0052040,GO:0052042,GO:0052150,GO:0052151,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052689,GO:0065007,GO:0071704,GO:0071944,GO:1901575 3.1.1.5 ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Bacteria 47R0A@768503,4NQ59@976,COG2267@1,COG2267@2 NA|NA|NA I Alpha/beta hydrolase family MAG.T22.3_03095 1239962.C943_04332 8.1e-191 672.9 Cytophagia 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 47TK4@768503,4NGZZ@976,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase MAG.T22.3_03096 1239962.C943_04333 0.0 1255.4 Bacteroidetes tilS 2.6.1.16,5.3.1.8,5.3.1.9,6.3.4.19 ko:K00820,ko:K04075,ko:K15916 ko00010,ko00030,ko00051,ko00250,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko04931,map00010,map00030,map00051,map00250,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map04931 M00001,M00004,M00114 R00768,R01819,R02739,R02740,R03321,R09597 RC00010,RC00163,RC00376,RC00563,RC02633,RC02634,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002,ko03016 Bacteria 4NIZR@976,COG0037@1,COG0037@2,COG0449@1,COG0449@2 NA|NA|NA D LPS biosynthesis protein MAG.T22.3_03097 1239962.C943_04334 3.3e-171 607.8 Cytophagia Bacteria 47VW0@768503,4NGFN@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase Family 4 MAG.T22.3_03098 1239962.C943_04335 2e-117 429.1 Cytophagia Bacteria 47VAV@768503,4NNRY@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.3_03099 1239962.C943_04336 1.1e-174 619.4 Bacteria lpg2 2.4.1.337 ko:K00754,ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups MAG.T22.3_03101 1239962.C943_04338 2.7e-226 791.2 Bacteria Bacteria COG2244@1,COG2244@2 NA|NA|NA S polysaccharide biosynthetic process MAG.T22.3_03102 1239962.C943_00421 1.5e-200 705.7 Cytophagia Bacteria 2FGQ8@1,348JR@2,47VVX@768503,4P6IS@976 NA|NA|NA MAG.T22.3_03104 1239962.C943_00420 3.3e-209 734.9 Bacteroidetes Bacteria 4P3C6@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.3_03106 1239962.C943_00418 3.6e-148 530.8 Bacteroidetes Bacteria 4PKQ2@976,COG1680@1,COG1680@2 NA|NA|NA V Fibrobacter succinogenes major paralogous MAG.T22.3_03109 929713.NIASO_05105 2.7e-24 119.8 Sphingobacteriia Bacteria 1IYQP@117747,2F7K7@1,3400T@2,4P4HE@976 NA|NA|NA MAG.T22.3_03110 1239962.C943_00414 2.9e-113 414.5 Cytophagia Bacteria 47PJ0@768503,4NFEG@976,COG3145@1,COG3145@2 NA|NA|NA L Alkylated DNA repair protein MAG.T22.3_03111 1120965.AUBV01000005_gene1864 2.9e-24 117.9 Bacteria ko:K07075 ko00000 Bacteria COG1669@1,COG1669@2 NA|NA|NA S nucleotidyltransferase activity MAG.T22.3_03112 866536.Belba_1642 3.6e-46 191.4 Cytophagia Bacteria 2AVE1@1,31M5W@2,47VUW@768503,4NS2G@976 NA|NA|NA MAG.T22.3_03113 1123057.P872_17560 4.6e-30 138.3 Cytophagia Bacteria 2F3AP@1,33W4W@2,47V6U@768503,4P3UB@976 NA|NA|NA MAG.T22.3_03115 1239962.C943_00409 9.7e-194 682.6 Cytophagia Bacteria 47KP7@768503,4NFQY@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase domain protein TIM barrel MAG.T22.3_03116 1239962.C943_00408 0.0 1805.4 Cytophagia ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 Bacteria 47JFX@768503,4NKBN@976,COG2133@1,COG2133@2,COG3291@1,COG3291@2,COG4654@1,COG4654@2 NA|NA|NA C Glucose / Sorbosone dehydrogenase MAG.T22.3_03117 1239962.C943_00406 0.0 1124.0 Cytophagia Bacteria 47JYR@768503,4NHH7@976,COG3119@1,COG3119@2 NA|NA|NA P PFAM sulfatase MAG.T22.3_03118 1123057.P872_09325 6.6e-272 943.0 Cytophagia Bacteria 47JYR@768503,4NHH7@976,COG3119@1,COG3119@2 NA|NA|NA P PFAM sulfatase MAG.T22.3_03119 1239962.C943_00405 9.5e-206 722.6 Cytophagia 1.14.13.222 ko:K21272 ko00000,ko01000 Bacteria 47NYU@768503,4NGIU@976,COG0654@1,COG0654@2 NA|NA|NA CH FAD binding domain MAG.T22.3_03120 1239962.C943_00404 2.9e-60 237.7 Cytophagia rimI2 Bacteria 47QE1@768503,4NRD5@976,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) domain MAG.T22.3_03121 1305737.JAFX01000001_gene2640 1.7e-183 649.0 Cytophagia Bacteria 2E3YY@1,32YVW@2,47W4W@768503,4NX9K@976 NA|NA|NA MAG.T22.3_03124 1239962.C943_00401 2e-231 808.1 Cytophagia ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 47NEQ@768503,4NGCG@976,COG2252@1,COG2252@2 NA|NA|NA S Permease family MAG.T22.3_03125 1239962.C943_00399 5.5e-144 516.9 Cytophagia mtnN 3.2.2.26,3.2.2.9 ko:K01243,ko:K11783 ko00130,ko00270,ko01100,ko01110,ko01230,map00130,map00270,map01100,map01110,map01230 M00034,M00609 R00194,R01401,R08587 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 Bacteria 47K2M@768503,4NMPF@976,COG0775@1,COG0775@2 NA|NA|NA F Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively MAG.T22.3_03127 1239962.C943_00397 2.8e-241 840.9 Cytophagia Bacteria 2EXB3@1,33QMU@2,47TYZ@768503,4PN16@976 NA|NA|NA MAG.T22.3_03128 1239962.C943_00396 7.9e-257 892.5 Cytophagia Bacteria 28KCX@1,2Z9ZQ@2,47JNB@768503,4NJ7S@976 NA|NA|NA MAG.T22.3_03129 1239962.C943_00393 7.7e-77 293.1 Cytophagia ko:K09705 ko00000 Bacteria 47PD8@768503,4NPCH@976,COG3542@1,COG3542@2 NA|NA|NA S Cupin superfamily (DUF985) MAG.T22.3_03130 1239962.C943_00392 9.3e-119 433.0 Cytophagia Bacteria 47MVM@768503,4NII9@976,COG4798@1,COG4798@2 NA|NA|NA S O-methyltransferase MAG.T22.3_03131 1239962.C943_00389 0.0 1467.6 Cytophagia ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 47N0R@768503,4NDUK@976,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain MAG.T22.3_03132 1239962.C943_00388 0.0 1478.0 Cytophagia ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 47MUE@768503,4NDUK@976,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain MAG.T22.3_03133 1239962.C943_00387 0.0 1450.3 Cytophagia ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 47TMG@768503,4NDUK@976,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain MAG.T22.3_03134 1239962.C943_00386 0.0 1529.2 Cytophagia ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 47JJN@768503,4NDUK@976,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family MAG.T22.3_03135 1239962.C943_00385 0.0 1523.5 Bacteroidetes ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 4NDUK@976,COG0577@1,COG0577@2 NA|NA|NA V permease MAG.T22.3_03136 1239962.C943_00384 2.4e-49 201.1 Cytophagia Bacteria 2E1JK@1,32WX8@2,47RMM@768503,4NTME@976 NA|NA|NA MAG.T22.3_03137 1239962.C943_00383 0.0 1491.5 Bacteroidetes ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 4NDUK@976,COG0577@1,COG0577@2 NA|NA|NA V permease MAG.T22.3_03138 1189612.A33Q_0571 2.2e-33 148.3 Cytophagia Bacteria 2DUPN@1,33RKB@2,47TQ0@768503,4P0X0@976 NA|NA|NA S Domain of unknown function (DUF4221) MAG.T22.3_03139 1189612.A33Q_0571 1.4e-80 306.2 Cytophagia Bacteria 2DUPN@1,33RKB@2,47TQ0@768503,4P0X0@976 NA|NA|NA S Domain of unknown function (DUF4221) MAG.T22.3_03140 1239962.C943_00380 0.0 1099.0 Cytophagia pruA 1.2.1.88 ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 R00245,R00707,R00708,R04444,R04445,R05051 RC00080,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000 Bacteria 47JZ2@768503,4NFTW@976,COG1012@1,COG1012@2 NA|NA|NA C TIGRFAM delta-1-pyrroline-5-carboxylate dehydrogenase, group 1 MAG.T22.3_03141 866536.Belba_0363 2.7e-29 135.6 Cytophagia Bacteria 2EWSH@1,33Q44@2,47TS3@768503,4P17F@976 NA|NA|NA MAG.T22.3_03142 1123057.P872_23850 8.8e-30 137.1 Cytophagia Bacteria 2C4CV@1,33SJ7@2,47UD7@768503,4P1HN@976 NA|NA|NA MAG.T22.3_03143 1239962.C943_00378 2.2e-125 454.9 Cytophagia yjjG GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006206,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008655,GO:0009058,GO:0009112,GO:0009410,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019856,GO:0019859,GO:0030145,GO:0034641,GO:0034654,GO:0042221,GO:0042578,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.102,3.1.3.104,3.1.3.5,3.8.1.2 ko:K01560,ko:K07025,ko:K08723,ko:K20862 ko00230,ko00240,ko00361,ko00625,ko00740,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00740,map00760,map01100,map01110,map01120 M00125 R00183,R00511,R00548,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287,R07280 RC00017,RC00697 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_4614 Bacteria 47Q1Q@768503,4NM66@976,COG1011@1,COG1011@2 NA|NA|NA S haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E MAG.T22.3_03144 1239962.C943_00377 9.6e-62 242.7 Cytophagia arsR ko:K03892 ko00000,ko03000 Bacteria 47QME@768503,4NSHB@976,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor MAG.T22.3_03145 1239962.C943_00376 1.6e-108 398.7 Cytophagia Bacteria 47Y7R@768503,4PN31@976,COG1629@1,COG1629@2 NA|NA|NA P CarboxypepD_reg-like domain MAG.T22.3_03146 1239962.C943_00375 5.1e-170 603.6 Cytophagia Bacteria 47PJS@768503,4NFHD@976,COG0668@1,COG0668@2 NA|NA|NA M Mechanosensitive ion channel MAG.T22.3_03147 1239962.C943_00374 7.6e-233 812.8 Bacteria Bacteria COG1409@1,COG1409@2 NA|NA|NA S acid phosphatase activity MAG.T22.3_03150 1239962.C943_00111 3.1e-234 817.4 Bacteroidetes Bacteria 4NHGJ@976,COG3356@1,COG3356@2 NA|NA|NA S PFAM Neutral alkaline nonlysosomal ceramidase MAG.T22.3_03151 1239962.C943_00112 1.1e-101 375.9 Cytophagia Bacteria 297E6@1,2ZUMN@2,47R84@768503,4NPTI@976 NA|NA|NA S DinB superfamily MAG.T22.3_03152 1239962.C943_00113 4.8e-102 377.1 Cytophagia maa 2.3.1.79 ko:K00661 ko00000,ko01000 Bacteria 47KBH@768503,4NNWE@976,COG0110@1,COG0110@2 NA|NA|NA S Maltose acetyltransferase MAG.T22.3_03153 1239962.C943_00114 0.0 1166.8 Cytophagia acd 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 Bacteria 47MIF@768503,4NEM4@976,COG1960@1,COG1960@2 NA|NA|NA I Acetyl-CoA dehydrogenase C-terminal like MAG.T22.3_03156 866536.Belba_3227 1.6e-49 202.2 Cytophagia Bacteria 47V3J@768503,4NQGU@976,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator MAG.T22.3_03157 866536.Belba_3226 1.6e-255 888.6 Cytophagia 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002,ko01000 3.D.4.3 Bacteria 47JV6@768503,4NEGM@976,COG3278@1,COG3278@2 NA|NA|NA C PFAM Cytochrome C and Quinol oxidase polypeptide I MAG.T22.3_03158 1123057.P872_12730 7.6e-119 433.7 Cytophagia ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 ko00000,ko00001,ko00002 3.D.4.3 Bacteria 47KNN@768503,4NEM7@976,COG2010@1,COG2010@2,COG2993@1,COG2993@2 NA|NA|NA C PFAM cytochrome C oxidase mono-heme subunit FixO MAG.T22.3_03159 1123057.P872_12735 8.9e-26 122.5 Cytophagia Bacteria 2E3IE@1,32YGW@2,47SQR@768503,4NTYY@976 NA|NA|NA S Hexameric tyrosine-coordinated heme protein (HTHP) MAG.T22.3_03160 1121912.AUHD01000007_gene437 8.7e-17 92.8 Flavobacteriia Bacteria 1I5SA@117743,2E58U@1,33018@2,4NVWZ@976 NA|NA|NA MAG.T22.3_03161 866536.Belba_3222 4.9e-59 233.8 Bacteroidetes Bacteria 2DURZ@1,32UXP@2,4PM0S@976 NA|NA|NA MAG.T22.3_03162 1123057.P872_12750 4e-47 194.1 Cytophagia ko:K06886 ko00000 Bacteria 47QQ0@768503,4NQCV@976,COG2346@1,COG2346@2 NA|NA|NA S PFAM Bacterial-like globin MAG.T22.3_03163 1046627.BZARG_694 1.6e-42 179.1 Flavobacteriia Bacteria 1I24Y@117743,4NP8M@976,COG5592@1,COG5592@2 NA|NA|NA S hemerythrin HHE cation binding domain MAG.T22.3_03164 1267211.KI669560_gene2574 6.4e-108 397.9 Bacteroidetes ko:K20971 ko02025,map02025 ko00000,ko00001,ko01001,ko02022 Bacteria 4NI1V@976,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MAG.T22.3_03165 1267211.KI669560_gene2573 2.1e-61 242.3 Bacteroidetes Bacteria 4NHTM@976,COG2197@1,COG2197@2 NA|NA|NA T Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain MAG.T22.3_03166 760192.Halhy_0517 3.8e-222 777.3 Sphingobacteriia Bacteria 1IX32@117747,2EWNT@1,33Q0R@2,4P09W@976 NA|NA|NA MAG.T22.3_03167 760192.Halhy_0518 1.1e-61 243.0 Sphingobacteriia Bacteria 1IXKF@117747,2F2JE@1,33VGC@2,4P2BN@976 NA|NA|NA MAG.T22.3_03168 760192.Halhy_0516 8.7e-24 115.9 Sphingobacteriia Bacteria 1IZS6@117747,28V12@1,2ZH4M@2,4P9A5@976 NA|NA|NA MAG.T22.3_03169 760192.Halhy_0519 2.1e-34 152.1 Sphingobacteriia Bacteria 1IZ47@117747,2C8ZK@1,346V3@2,4P69K@976 NA|NA|NA MAG.T22.3_03170 760192.Halhy_0520 5.2e-92 344.4 Sphingobacteriia Bacteria 1IW7S@117747,2C8ZM@1,33PDW@2,4P0QI@976 NA|NA|NA MAG.T22.3_03171 1267211.KI669560_gene2659 2.1e-150 538.9 Sphingobacteriia Bacteria 1IYQN@117747,2CEQ8@1,340WM@2,4P48T@976 NA|NA|NA MAG.T22.3_03172 760192.Halhy_0515 0.0 1095.5 Sphingobacteriia Bacteria 1IYI2@117747,4P9P7@976,COG4642@1,COG4642@2 NA|NA|NA S MORN repeat MAG.T22.3_03175 1120968.AUBX01000017_gene2014 1.8e-143 515.4 Cytophagia traC Bacteria 47PIP@768503,4NM80@976,COG4227@1,COG4227@2 NA|NA|NA L Domain of unknown function (DUF1738) MAG.T22.3_03177 1408254.T458_12860 7.2e-138 497.3 Paenibacillaceae mod 2.1.1.72 ko:K07316 ko00000,ko01000,ko02048 Bacteria 1TR8A@1239,26T0A@186822,4HBP1@91061,COG2189@1,COG2189@2 NA|NA|NA L DNA methylase MAG.T22.3_03178 1123035.ARLA01000027_gene306 2e-126 458.8 Flavobacteriia Bacteria 1IIAH@117743,4NGGI@976,COG4823@1,COG4823@2 NA|NA|NA V Abi-like protein MAG.T22.3_03179 1168034.FH5T_06270 5e-11 75.1 Bacteroidia 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2FWTI@200643,4NI7S@976,COG2865@1,COG2865@2 NA|NA|NA K Putative ATP-dependent DNA helicase recG C-terminal MAG.T22.3_03180 61647.LG71_10245 1.3e-43 185.3 Gammaproteobacteria 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1R4D4@1224,1SJN6@1236,COG3973@1,COG3973@2,COG5635@1,COG5635@2 NA|NA|NA L UvrD-like helicase C-terminal domain MAG.T22.3_03181 1288963.ADIS_1331 0.0 1741.1 Cytophagia res 3.1.21.5 ko:K01156 ko00000,ko01000,ko02048 Bacteria 47NJ5@768503,4NGM0@976,COG3587@1,COG3587@2 NA|NA|NA V Type III restriction enzyme, res subunit MAG.T22.3_03182 1048983.EL17_11040 7.7e-96 357.5 Bacteria Bacteria 28WBU@1,2ZIC8@2 NA|NA|NA MAG.T22.3_03183 1288963.ADIS_1333 0.0 1809.7 Cytophagia Bacteria 47N8P@768503,4NH3B@976,COG0553@1,COG0553@2 NA|NA|NA L SNF2 family N-terminal domain MAG.T22.3_03184 1288963.ADIS_1334 6.2e-45 187.6 Cytophagia Bacteria 28NQ0@1,2ZBPR@2,47V6F@768503,4NQJC@976 NA|NA|NA S Domain of unknown function (DUF4391) MAG.T22.3_03186 926562.Oweho_3416 1.1e-49 203.0 Bacteroidetes Bacteria 4P4NT@976,COG1403@1,COG1403@2 NA|NA|NA V HNH endonuclease MAG.T22.3_03187 1122978.AUFP01000026_gene831 1.1e-68 266.9 Bacteroidia 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 R01416 RC00177 ko00000,ko00001,ko01000 Bacteria 2FSKH@200643,4NRPH@976,COG2957@1,COG2957@2 NA|NA|NA E Belongs to the agmatine deiminase family MAG.T22.3_03189 1120965.AUBV01000005_gene1662 2.9e-117 428.7 Cytophagia 3.4.16.4 ko:K01286 ko00000,ko01000 Bacteria 47XBS@768503,4NNBR@976,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T22.3_03190 1239962.C943_01290 1.1e-64 252.7 Cytophagia ko:K03791 ko00000 GH19 Bacteria 47T29@768503,4NW30@976,COG3108@1,COG3108@2 NA|NA|NA S Peptidase M15 MAG.T22.3_03191 1239962.C943_01289 4.3e-38 163.7 Cytophagia Bacteria 2E1TV@1,32X3J@2,47X0Q@768503,4NTUS@976 NA|NA|NA S Bor protein MAG.T22.3_03193 1239962.C943_01287 1.5e-100 372.1 Cytophagia Bacteria 47R70@768503,4NQQP@976,COG0664@1,COG0664@2 NA|NA|NA K Transcriptional regulator, Crp Fnr family MAG.T22.3_03195 1239962.C943_01286 1.1e-169 602.4 Cytophagia Bacteria 47MFK@768503,4NGMY@976,COG5285@1,COG5285@2 NA|NA|NA Q Phytanoyl-CoA dioxygenase (PhyH) MAG.T22.3_03196 1239962.C943_01285 5.2e-153 547.0 Cytophagia mltR Bacteria 47MSY@768503,4NE6T@976,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein MAG.T22.3_03197 1239962.C943_01284 8.1e-310 1068.9 Cytophagia yidK Bacteria 47K2R@768503,4NEN8@976,COG0591@1,COG0591@2 NA|NA|NA E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family MAG.T22.3_03198 1239962.C943_01283 0.0 1614.7 Cytophagia mca ko:K22136 ko00000 Bacteria 47KXK@768503,4NE9K@976,COG2120@1,COG2120@2 NA|NA|NA G PFAM GlcNAc-PI de-N-acetylase MAG.T22.3_03199 1239962.C943_01281 2.3e-181 641.3 Cytophagia kynA GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009150,GO:0009165,GO:0009259,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034654,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11,4.1.1.45 ko:K00453,ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R00678,R04323 RC00356,RC00779 ko00000,ko00001,ko00002,ko01000 Bacteria 47KCQ@768503,4NFG4@976,COG3483@1,COG3483@2 NA|NA|NA E Tryptophan 2,3-dioxygenase MAG.T22.3_03200 1239962.C943_01280 1.5e-233 815.1 Cytophagia gcdH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 Bacteria 47KQK@768503,4NEKJ@976,COG1960@1,COG1960@2 NA|NA|NA I acyl-CoA dehydrogenase MAG.T22.3_03201 1239962.C943_01279 1.4e-256 892.1 Bacteroidetes 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 4NEVN@976,COG0457@1,COG0457@2,COG2114@1,COG2114@2 NA|NA|NA T Belongs to the adenylyl cyclase class-4 guanylyl cyclase family MAG.T22.3_03202 643867.Ftrac_1354 4e-08 64.3 Cytophagia Bacteria 297ZM@1,2ZV5R@2,47X02@768503,4P842@976 NA|NA|NA MAG.T22.3_03205 861299.J421_2228 1.9e-32 146.7 Gemmatimonadetes 1.23.1.1,1.23.1.2,1.23.1.3,1.23.1.4 ko:K21568 ko00000,ko01000 Bacteria 1ZV6Y@142182,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family MAG.T22.3_03206 316274.Haur_1430 9.7e-131 474.9 Chloroflexia 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 2G699@200795,3764S@32061,COG0457@1,COG0457@2,COG2114@1,COG2114@2,COG3899@1,COG3899@2 NA|NA|NA T PFAM adenylyl cyclase class-3 4 guanylyl cyclase MAG.T22.3_03207 1123037.AUDE01000023_gene2809 1.8e-07 62.8 Bacteria Bacteria COG3631@1,COG3631@2 NA|NA|NA S light absorption MAG.T22.3_03208 1239962.C943_04199 3.5e-291 1006.9 Cytophagia IV02_08645 ko:K07137 ko00000 Bacteria 47K0W@768503,4NEUQ@976,COG2509@1,COG2509@2 NA|NA|NA S FAD dependent oxidoreductase MAG.T22.3_03209 1239962.C943_04200 4.7e-205 720.3 Cytophagia ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2 Bacteria 47SKB@768503,4PKYV@976,COG1317@1,COG1317@2 NA|NA|NA NU Lipid A 3-O-deacylase (PagL) MAG.T22.3_03210 1239962.C943_04201 4.8e-224 783.5 Cytophagia Bacteria 47PQF@768503,4NFHT@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.3_03211 1239962.C943_04202 0.0 1608.6 Cytophagia gyrA 5.99.1.3 ko:K02469 ko00000,ko01000,ko03032,ko03400 Bacteria 47K30@768503,4NDWQ@976,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner MAG.T22.3_03212 1239962.C943_04203 7.1e-186 656.4 Cytophagia Bacteria 2EG6T@1,339YP@2,47T48@768503,4NXNK@976 NA|NA|NA MAG.T22.3_03213 1239962.C943_04204 1.7e-82 312.0 Cytophagia Bacteria 2BZCX@1,33XUD@2,47V4G@768503,4P3BB@976 NA|NA|NA MAG.T22.3_03214 1239962.C943_04205 8.8e-116 422.9 Cytophagia rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1718 Bacteria 47N3P@768503,4NDXB@976,COG0036@1,COG0036@2 NA|NA|NA G Belongs to the ribulose-phosphate 3-epimerase family MAG.T22.3_03215 1239962.C943_04207 2.7e-307 1060.4 Cytophagia aprN Bacteria 47KS3@768503,4NEIJ@976,COG1404@1,COG1404@2 NA|NA|NA O Peptidase S8 and S53 subtilisin kexin sedolisin MAG.T22.3_03216 1189612.A33Q_3635 1.7e-64 252.7 Bacteroidetes Bacteria 298K1@1,2ZVQX@2,4NNNX@976 NA|NA|NA MAG.T22.3_03217 1239962.C943_04209 2.7e-114 417.9 Cytophagia trpF 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 47PJ8@768503,4NMKY@976,COG0135@1,COG0135@2 NA|NA|NA E isomerase MAG.T22.3_03218 1239962.C943_04210 1.4e-175 622.1 Cytophagia hemF GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 Bacteria 47M0F@768503,4NFZS@976,COG0408@1,COG0408@2 NA|NA|NA H PFAM coproporphyrinogen III oxidase MAG.T22.3_03219 1239962.C943_04211 2.5e-106 391.3 Cytophagia ybjG 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 47RBP@768503,4NNVQ@976,COG0671@1,COG0671@2 NA|NA|NA I PFAM PAP2 superfamily MAG.T22.3_03221 1239962.C943_00110 1.3e-196 692.2 Cytophagia ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1.106 Bacteria 47MDS@768503,4NE19@976,COG2274@1,COG2274@2 NA|NA|NA V ABC transporter transmembrane region MAG.T22.3_03222 866536.Belba_3188 3.5e-117 428.7 Cytophagia Bacteria 2CM4X@1,33R4J@2,47UEV@768503,4P113@976 NA|NA|NA MAG.T22.3_03224 1239962.C943_04046 3.6e-162 577.4 Bacteroidetes 5.1.3.30,5.1.3.31 ko:K18910 R10817,R10818 RC03111,RC03283 ko00000,ko01000 Bacteria 4NHGW@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase domain protein TIM barrel MAG.T22.3_03225 1239962.C943_04043 1.7e-198 698.4 Cytophagia Bacteria 47PM9@768503,4NIEV@976,COG3828@1,COG3828@2 NA|NA|NA S Trehalose utilisation MAG.T22.3_03226 1239962.C943_04042 1e-265 922.2 Cytophagia Bacteria 47KXX@768503,4NG19@976,COG5297@1,COG5297@2 NA|NA|NA G Protein of unknown function (DUF1593) MAG.T22.3_03227 1239962.C943_04039 1.3e-162 578.9 Cytophagia Bacteria 47JUA@768503,4NH62@976,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold MAG.T22.3_03228 1239962.C943_04037 0.0 2082.8 Cytophagia ko:K08676 ko00000,ko01000,ko01002 Bacteria 47KCJ@768503,4NGU2@976,COG0793@1,COG0793@2,COG4946@1,COG4946@2 NA|NA|NA M Tricorn protease homolog MAG.T22.3_03229 1239962.C943_04036 3.5e-106 391.0 Cytophagia Bacteria 28ICV@1,2Z8F4@2,47XPT@768503,4NEKU@976 NA|NA|NA S Protein of unknown function (DUF4230) MAG.T22.3_03230 1239962.C943_04032 0.0 3649.0 Cytophagia spaI Bacteria 47KNM@768503,4NHSQ@976,COG1404@1,COG1404@2,COG4932@1,COG4932@2 NA|NA|NA O Subtilase family MAG.T22.3_03232 1239962.C943_04031 3.3e-264 917.1 Cytophagia Bacteria 47M3C@768503,4NEM3@976,COG3119@1,COG3119@2 NA|NA|NA P PFAM sulfatase MAG.T22.3_03233 1239962.C943_04030 4.5e-141 507.3 Cytophagia tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 ko:K02357 ko00000,ko03012,ko03029 Bacteria 47M4X@768503,4NF03@976,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome MAG.T22.3_03234 1239962.C943_04029 6.4e-134 483.4 Cytophagia rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47M3D@768503,4NER0@976,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family MAG.T22.3_03235 1189612.A33Q_0117 2.6e-59 234.6 Cytophagia rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47Q9B@768503,4NNN1@976,COG0103@1,COG0103@2 NA|NA|NA J Belongs to the universal ribosomal protein uS9 family MAG.T22.3_03236 1239962.C943_04027 1.2e-79 302.4 Cytophagia rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47PQ7@768503,4NNGA@976,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly MAG.T22.3_03237 1239962.C943_04026 4.6e-134 483.8 Cytophagia 5.4.99.24 ko:K06179 ko00000,ko01000,ko03009 Bacteria 47KJC@768503,4NHKH@976,COG0564@1,COG0564@2 NA|NA|NA J TIGRFAM pseudouridine synthase, RluA family MAG.T22.3_03238 1239962.C943_04025 1.2e-191 675.6 Cytophagia phoR 2.7.13.3 ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 47JX1@768503,4NETP@976,COG5002@1,COG5002@2 NA|NA|NA T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MAG.T22.3_03239 1239962.C943_04024 2.7e-123 448.0 Cytophagia Bacteria 47MJ5@768503,4NG7D@976,COG0745@1,COG0745@2 NA|NA|NA T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain MAG.T22.3_03240 1239962.C943_04023 4.2e-136 490.7 Cytophagia Bacteria 47M60@768503,4NF47@976,COG3170@1,COG3170@2 NA|NA|NA NU Protein of unknown function (DUF3108) MAG.T22.3_03241 1239962.C943_04022 1.4e-187 662.1 Cytophagia recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 47K6D@768503,4NEXT@976,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage MAG.T22.3_03242 1239962.C943_04021 5.4e-207 726.9 Cytophagia ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 47J9P@768503,4NECN@976,COG0577@1,COG0577@2 NA|NA|NA V ABC-type antimicrobial peptide transport system, permease component MAG.T22.3_03243 866536.Belba_0039 4e-179 634.0 Cytophagia queA 2.4.99.17 ko:K07568 ko00000,ko01000,ko03016 Bacteria 47J9B@768503,4NF2T@976,COG0809@1,COG0809@2 NA|NA|NA J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) MAG.T22.3_03244 1239962.C943_04019 1.4e-119 435.6 Cytophagia ispD GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60,4.6.1.12 ko:K00991,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 Bacteria 47P6K@768503,4NMB5@976,COG1211@1,COG1211@2 NA|NA|NA I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) MAG.T22.3_03245 1239962.C943_04018 3.9e-142 510.8 Cytophagia Bacteria 47PGU@768503,4NQRE@976,COG4758@1,COG4758@2 NA|NA|NA S membrane protein (DUF2154) MAG.T22.3_03246 1239962.C943_04017 1.9e-184 651.7 Cytophagia Bacteria 47NHD@768503,4NHG3@976,COG2972@1,COG2972@2 NA|NA|NA T Histidine kinase MAG.T22.3_03247 1239962.C943_04016 1.3e-128 465.7 Cytophagia ko:K02477 ko00000,ko02022 Bacteria 47KUT@768503,4NEAH@976,COG3279@1,COG3279@2 NA|NA|NA KT Response regulator of the LytR AlgR family MAG.T22.3_03248 1189612.A33Q_0102 2e-35 154.5 Cytophagia Bacteria 2C8VT@1,32RN1@2,47R0I@768503,4NS78@976 NA|NA|NA S Protein of unknown function (DUF2795) MAG.T22.3_03249 1239962.C943_04014 5.1e-229 800.0 Cytophagia ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 47K0U@768503,4NJ9Y@976,COG1196@1,COG1196@2 NA|NA|NA D Domain of Unknown Function (DUF349) MAG.T22.3_03250 1239962.C943_04013 0.0 1083.9 Cytophagia yjjK GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 ko:K06020 ko00000,ko01000 Bacteria 47M5V@768503,4NES5@976,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter MAG.T22.3_03251 866536.Belba_3734 1.2e-61 243.0 Bacteroidetes Bacteria 2C6AJ@1,32RGZ@2,4NRBU@976 NA|NA|NA MAG.T22.3_03252 866536.Belba_3735 1e-32 146.7 Cytophagia ko:K12057 ko00000,ko02044 3.A.7.11.1 Bacteria 47SQI@768503,4NY16@976,COG0526@1,COG0526@2 NA|NA|NA CO AhpC/TSA family MAG.T22.3_03253 1189612.A33Q_0698 6.7e-293 1013.1 Cytophagia ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21 Bacteria 47TTE@768503,4NE19@976,COG2274@1,COG2274@2 NA|NA|NA V Peptidase C39 family MAG.T22.3_03254 866536.Belba_3738 3e-17 94.0 Cytophagia Bacteria 2DG4S@1,2ZUHD@2,47WMQ@768503,4P7BX@976 NA|NA|NA MAG.T22.3_03256 1123057.P872_02545 1.1e-31 142.9 Cytophagia Bacteria 2DE8I@1,2ZKZ3@2,47WX4@768503,4P8M1@976 NA|NA|NA MAG.T22.3_03260 1305737.JAFX01000001_gene2422 2.2e-48 198.4 Bacteroidetes Bacteria 4PMPP@976,COG1848@1,COG1848@2 NA|NA|NA S PIN domain MAG.T22.3_03261 1239962.C943_04012 0.0 1136.3 Cytophagia pnbA ko:K03929 ko00000,ko01000 CE10 Bacteria 47JGD@768503,4NG5B@976,COG2272@1,COG2272@2 NA|NA|NA I Belongs to the type-B carboxylesterase lipase family MAG.T22.3_03262 1239962.C943_04011 0.0 1390.2 Cytophagia ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 47JJN@768503,4NDUK@976,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family MAG.T22.3_03263 1239962.C943_04010 0.0 1435.6 Cytophagia ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 47M0S@768503,4NDUK@976,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain MAG.T22.3_03264 1239962.C943_04008 2.4e-193 681.4 Cytophagia Bacteria 47MDV@768503,4NG9U@976,COG2159@1,COG2159@2 NA|NA|NA S PFAM Amidohydrolase 2 MAG.T22.3_03265 1239962.C943_04007 1.5e-118 432.2 Cytophagia tonB ko:K03832 ko00000,ko02000 2.C.1.1 Bacteria 47KAX@768503,4NMG7@976,COG0810@1,COG0810@2 NA|NA|NA U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins MAG.T22.3_03266 1239962.C943_04006 1e-98 366.3 Cytophagia tonB ko:K03832 ko00000,ko02000 2.C.1.1 Bacteria 47XHA@768503,4NFH6@976,COG0810@1,COG0810@2 NA|NA|NA M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins MAG.T22.3_03267 1239962.C943_04005 2.3e-60 238.0 Cytophagia gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 47QD7@768503,4NQ35@976,COG0509@1,COG0509@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein MAG.T22.3_03268 1239962.C943_04004 0.0 4541.1 Cytophagia sprA Bacteria 47K4H@768503,4PKQS@976,COG4797@1,COG4797@2 NA|NA|NA D Motility related/secretion protein MAG.T22.3_03269 1239962.C943_04002 3e-102 377.9 Cytophagia ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 47N8D@768503,4NF4E@976,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB MAG.T22.3_03270 1189612.A33Q_2049 0.0 1266.1 Cytophagia maeB GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 ko:K00027,ko:K00029,ko:K00625,ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,ko02020,map00430,map00620,map00640,map00680,map00710,map00720,map01100,map01120,map01200,map02020 M00169,M00172,M00357,M00579 R00214,R00216,R00230,R00921 RC00004,RC00105,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1637 Bacteria 47JSR@768503,4NFUJ@976,COG0280@1,COG0280@2,COG0281@1,COG0281@2 NA|NA|NA C Phosphate acetyl butaryl transferase MAG.T22.3_03271 1239962.C943_04000 8.9e-185 652.9 Cytophagia uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 47NDQ@768503,4NGEV@976,COG0322@1,COG0322@2 NA|NA|NA L Domain of unknown function (DUF4837) MAG.T22.3_03272 1239962.C943_03999 2.8e-255 887.5 Cytophagia mltD ko:K08307,ko:K12204 ko00000,ko01000,ko01011,ko02044 3.A.7.10.1,3.A.7.9.1 Bacteria 47KJK@768503,4NEKW@976,COG0741@1,COG0741@2,COG1388@1,COG1388@2 NA|NA|NA M PFAM Transglycosylase SLT domain MAG.T22.3_03273 1239962.C943_03998 1.1e-259 902.1 Cytophagia gatA 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 47JDQ@768503,4NF8C@976,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) MAG.T22.3_03274 1239962.C943_03997 1.6e-20 104.8 Bacteria tatA ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria COG1826@1,COG1826@2 NA|NA|NA U protein secretion MAG.T22.3_03275 1239962.C943_03996 1.7e-184 652.1 Cytophagia envC Bacteria 47JWJ@768503,4NH2T@976,COG4942@1,COG4942@2 NA|NA|NA D Peptidase, M23 MAG.T22.3_03276 1239962.C943_03995 3.7e-131 474.2 Cytophagia ko:K03634 ko00000 Bacteria 47N94@768503,4NFYQ@976,COG2834@1,COG2834@2 NA|NA|NA M Domain of unknown function (DUF4292) MAG.T22.3_03277 1239962.C943_03994 1.3e-174 619.8 Cytophagia Bacteria 47KE1@768503,4NDVW@976,COG0457@1,COG0457@2 NA|NA|NA S PFAM Tetratricopeptide MAG.T22.3_03278 1239962.C943_03993 6.8e-72 276.6 Cytophagia dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 47PPG@768503,4NNI4@976,COG0756@1,COG0756@2 NA|NA|NA F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA MAG.T22.3_03279 1239962.C943_03992 9.1e-273 945.7 Cytophagia cap Bacteria 47MQE@768503,4NDZ0@976,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein MAG.T22.3_03280 1239962.C943_03991 3.8e-140 504.2 Cytophagia crt 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 R03026 RC00831 ko00000,ko00001,ko01000 Bacteria 47JUC@768503,4NFEM@976,COG1024@1,COG1024@2 NA|NA|NA I Belongs to the enoyl-CoA hydratase isomerase family MAG.T22.3_03281 1239962.C943_03990 5.8e-277 959.5 Cytophagia icd 1.1.1.41,1.1.1.42 ko:K00030,ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R00709,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 47KD2@768503,4NGUA@976,COG0473@1,COG0473@2 NA|NA|NA CE Isocitrate dehydrogenase MAG.T22.3_03282 1239962.C943_03989 3.3e-225 787.3 Cytophagia ko:K07133 ko00000 Bacteria 47V3W@768503,4NG8U@976,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) MAG.T22.3_03283 1239962.C943_03988 0.0 1190.6 Cytophagia typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 47KWA@768503,4NDVM@976,COG1217@1,COG1217@2 NA|NA|NA T GTP-binding protein TypA MAG.T22.3_03284 1189612.A33Q_2033 2.6e-81 308.5 Cytophagia Bacteria 28TRC@1,2ZFYJ@2,47SSW@768503,4NH2D@976 NA|NA|NA MAG.T22.3_03285 866536.Belba_0083 1.8e-34 152.9 Cytophagia Bacteria 2EXWC@1,33R5G@2,47TQD@768503,4P25Z@976 NA|NA|NA MAG.T22.3_03286 1239962.C943_03980 4.2e-59 233.8 Cytophagia Bacteria 47RGZ@768503,4NQBA@976,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family MAG.T22.3_03287 1123057.P872_25445 1.1e-45 190.3 Cytophagia Bacteria 2FF0Y@1,346ZC@2,47W0R@768503,4P5CB@976 NA|NA|NA MAG.T22.3_03288 1239962.C943_03978 0.0 1363.2 Bacteria Bacteria COG2885@1,COG2885@2 NA|NA|NA M chlorophyll binding MAG.T22.3_03289 1239962.C943_03977 1e-202 712.6 Cytophagia Bacteria 28UQ5@1,2ZGUJ@2,47TQT@768503,4NM5U@976 NA|NA|NA MAG.T22.3_03290 1239962.C943_03976 5.3e-41 173.3 Cytophagia M1-594 Bacteria 47RVT@768503,4NVNG@976,COG0011@1,COG0011@2 NA|NA|NA S Thiamine-binding protein MAG.T22.3_03291 1239962.C943_03975 2.6e-110 404.8 Cytophagia 3.2.1.14,3.2.1.4 ko:K01179,ko:K01183 ko00500,ko00520,ko01100,map00500,map00520,map01100 R01206,R02334,R06200,R11307,R11308 RC00467 ko00000,ko00001,ko01000 GH18,GH5,GH9 Bacteria 47XTS@768503,4NR24@976,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase family MAG.T22.3_03292 1239962.C943_03973 1.2e-186 659.1 Cytophagia Bacteria 47MMQ@768503,4NFY7@976,COG4192@1,COG4192@2 NA|NA|NA T Domain of unknown function (DUF4407) MAG.T22.3_03293 1239962.C943_03972 2e-130 471.9 Cytophagia Bacteria 2DBMF@1,2Z9YG@2,47Q6I@768503,4NPRW@976 NA|NA|NA MAG.T22.3_03294 1239962.C943_03971 1.3e-120 439.1 Cytophagia Bacteria 47M4I@768503,4NE6W@976,COG1814@1,COG1814@2 NA|NA|NA S VIT family MAG.T22.3_03295 1239962.C943_03970 1.9e-198 698.4 Cytophagia 3.4.13.19 ko:K01273 ko00000,ko00537,ko01000,ko01002,ko04147 Bacteria 47JZD@768503,4NEBG@976,COG2355@1,COG2355@2 NA|NA|NA E Membrane dipeptidase (Peptidase family M19) MAG.T22.3_03296 1239962.C943_03969 1e-108 399.4 Cytophagia Bacteria 2D0I5@1,32T8N@2,47S13@768503,4NSMU@976 NA|NA|NA S Four helix bundle sensory module for signal transduction MAG.T22.3_03297 867902.Ornrh_1339 3.2e-24 118.2 Flavobacteriia Bacteria 1IB6J@117743,28XUR@1,2ZJR4@2,4P7EC@976 NA|NA|NA MAG.T22.3_03298 866536.Belba_1017 4.2e-173 614.4 Cytophagia ko:K04763 ko00000,ko03036 Bacteria 47KKB@768503,4NGE1@976,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family MAG.T22.3_03299 1239962.C943_01862 3.1e-112 411.4 Cytophagia CP_0228 3.5.4.16 ko:K07164,ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 47JBK@768503,4NE36@976,COG1579@1,COG1579@2 NA|NA|NA S Zn-ribbon protein, possibly nucleic acid-binding MAG.T22.3_03300 1239962.C943_01863 3.7e-199 700.7 Cytophagia yqfO 3.5.4.16 ko:K07164,ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 47JGH@768503,4NF51@976,COG0327@1,COG0327@2 NA|NA|NA S Belongs to the GTP cyclohydrolase I type 2 NIF3 family MAG.T22.3_03301 1239962.C943_01864 2.7e-183 647.9 Cytophagia lpxK GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396 Bacteria 47M44@768503,4NE2I@976,COG1663@1,COG1663@2 NA|NA|NA M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) MAG.T22.3_03302 1239962.C943_01865 0.0 1327.4 Cytophagia ko:K02014 ko00000,ko02000 1.B.14 Bacteria 47JRI@768503,4NI2R@976,COG4206@1,COG4206@2 NA|NA|NA H Putative porin MAG.T22.3_03303 1239962.C943_01866 4.9e-102 377.1 Cytophagia miaE ko:K06169 ko00000,ko01000,ko03016 Bacteria 47P6J@768503,4NFY4@976,COG4445@1,COG4445@2 NA|NA|NA FJ Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA MAG.T22.3_03304 1239962.C943_01867 1.7e-221 775.0 Cytophagia ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 47KYR@768503,4NEBD@976,COG0577@1,COG0577@2 NA|NA|NA V ABC-type antimicrobial peptide transport system, permease component MAG.T22.3_03305 1239962.C943_01868 0.0 1133.6 Cytophagia Bacteria 47JIT@768503,4NHJT@976,COG2303@1,COG2303@2 NA|NA|NA E GMC oxidoreductase MAG.T22.3_03306 1239962.C943_01870 0.0 1328.5 Cytophagia Bacteria 47NCY@768503,4NEKT@976,COG1305@1,COG1305@2 NA|NA|NA E Domain of Unknown Function with PDB structure (DUF3857) MAG.T22.3_03307 1239962.C943_01871 0.0 1267.3 Cytophagia Bacteria 47JVH@768503,4NE7G@976,COG1305@1,COG1305@2 NA|NA|NA E Domain of Unknown Function with PDB structure (DUF3857) MAG.T22.3_03308 1239962.C943_01872 2.5e-234 817.8 Cytophagia yqeV GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 ko:K18707 R10649 RC00003,RC03221 ko00000,ko01000,ko03016 Bacteria 47MPX@768503,4NE0R@976,COG0621@1,COG0621@2 NA|NA|NA J TIGRFAM MiaB-like tRNA modifying enzyme MAG.T22.3_03309 1239962.C943_01874 0.0 1400.2 Cytophagia glnA 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 47KK6@768503,4NG2B@976,COG3968@1,COG3968@2 NA|NA|NA S glutamine synthetase MAG.T22.3_03312 1239962.C943_01875 0.0 2092.8 Cytophagia Bacteria 47M35@768503,4NDU8@976,COG1629@1,COG4771@2 NA|NA|NA P PFAM TonB-dependent Receptor Plug MAG.T22.3_03313 1239962.C943_01876 2.3e-295 1020.8 Cytophagia Bacteria 47JVY@768503,4PKAT@976,COG0521@1,COG0521@2 NA|NA|NA H Starch-binding associating with outer membrane MAG.T22.3_03314 1239962.C943_01877 1.8e-212 745.0 Cytophagia 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 R01206,R02334 RC00467 ko00000,ko00001,ko01000 GH18 Bacteria 47JXX@768503,4NGAZ@976,COG3325@1,COG3325@2 NA|NA|NA G Glyco_18 MAG.T22.3_03315 1239962.C943_01878 8.6e-182 642.9 Cytophagia ko:K02529,ko:K03435 ko00000,ko03000 Bacteria 47NJN@768503,4NESN@976,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor MAG.T22.3_03316 926562.Oweho_0002 9.6e-55 219.9 Cryomorphaceae hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1HYSD@117743,2PAG5@246874,4NG0E@976,COG0286@1,COG0286@2 NA|NA|NA V TIGRFAM type I restriction system adenine methylase (hsdM) MAG.T22.3_03317 314230.DSM3645_05630 4.6e-85 322.0 Planctomycetes hsdS 2.1.1.72,3.1.21.3 ko:K01154,ko:K03427 ko00000,ko01000,ko02048 Bacteria 2J0FU@203682,COG0732@1,COG0732@2 NA|NA|NA V COG0732 Restriction endonuclease S subunits MAG.T22.3_03318 866536.Belba_2139 7.1e-81 307.8 Bacteroidetes Bacteria 2C171@1,2Z7ZR@2,4NPU9@976 NA|NA|NA S SIR2-like domain MAG.T22.3_03319 926559.JoomaDRAFT_3764 3.3e-171 608.6 Flavobacteriia ko:K06915 ko00000 Bacteria 1I082@117743,4NH3W@976,COG0433@1,COG0433@2 NA|NA|NA S Domain of unknown function DUF87 MAG.T22.3_03320 1392498.JQLH01000001_gene3340 2.3e-29 134.8 Flavobacteriia Bacteria 1IKAV@117743,4NRXY@976,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix MAG.T22.3_03321 1392498.JQLH01000001_gene3341 2.7e-161 575.1 Flavobacteriia 2.7.11.1 ko:K07154 ko00000,ko01000,ko01001,ko02048 Bacteria 1HXAI@117743,4NFYY@976,COG3550@1,COG3550@2 NA|NA|NA S Pfam:HipA_N MAG.T22.3_03322 926559.JoomaDRAFT_1790 1.1e-36 160.2 Flavobacteriia 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1HZVM@117743,4NGFJ@976,COG2865@1,COG2865@2 NA|NA|NA K Putative ATP-dependent DNA helicase recG C-terminal MAG.T22.3_03324 1120966.AUBU01000024_gene543 0.0 1932.5 Cytophagia hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 47N2P@768503,4NFJ8@976,COG0610@1,COG0610@2 NA|NA|NA V Subunit R is required for both nuclease and ATPase activities, but not for modification MAG.T22.3_03325 997884.HMPREF1068_02181 1.1e-14 85.9 Bacteroidia 3.1.11.5 ko:K03581,ko:K07452,ko:K09384 ko03440,map03440 ko00000,ko00001,ko01000,ko02048,ko03400 Bacteria 2FX6P@200643,4PAJY@976,COG0507@1,COG0507@2 NA|NA|NA L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD MAG.T22.3_03326 1239962.C943_04225 0.0 1144.4 Cytophagia kefC GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006885,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010033,GO:0015075,GO:0015077,GO:0015079,GO:0015291,GO:0015318,GO:0015503,GO:0015643,GO:0015672,GO:0016020,GO:0016021,GO:0019899,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051595,GO:0055067,GO:0055080,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:1901654,GO:1901700 ko:K03455,ko:K11745,ko:K11747 ko00000,ko02000 2.A.37,2.A.37.1.1,2.A.37.1.2 iECOK1_1307.ECOK1_0046,iECS88_1305.ECS88_0050,iUMN146_1321.UM146_23015,iUTI89_1310.UTI89_C0053 Bacteria 47NEG@768503,4NGF6@976,COG0475@1,COG0475@2,COG1226@1,COG1226@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family MAG.T22.3_03327 1239962.C943_04224 7.2e-101 373.2 Cytophagia yheR ko:K11748 ko00000,ko02000 2.A.37.1.2 Bacteria 47PTZ@768503,4NGF7@976,COG2249@1,COG2249@2 NA|NA|NA S Flavodoxin-like fold MAG.T22.3_03328 1239962.C943_04221 3.9e-93 347.4 Cytophagia ykhA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.2.20 ko:K01073 ko00000,ko01000 Bacteria 47P9H@768503,4NERA@976,COG1607@1,COG1607@2 NA|NA|NA I PFAM thioesterase superfamily MAG.T22.3_03330 1239962.C943_04215 7.8e-120 436.4 Cytophagia pcm GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 ko:K00573 ko00000,ko01000 Bacteria 47P7V@768503,4NFCU@976,COG2518@1,COG2518@2 NA|NA|NA J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins MAG.T22.3_03331 1239962.C943_04214 3.3e-109 401.0 Cytophagia ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 iYO844.BSU23270 Bacteria 47JY5@768503,4NHI8@976,COG0307@1,COG0307@2 NA|NA|NA H TIGRFAM riboflavin synthase, alpha subunit MAG.T22.3_03332 1239962.C943_02795 2.8e-108 397.9 Bacteria Bacteria COG3391@1,COG3391@2 NA|NA|NA CO amine dehydrogenase activity MAG.T22.3_03333 1288963.ADIS_0511 1e-63 250.0 Bacteria Bacteria COG2197@1,COG2197@2 NA|NA|NA K response regulator MAG.T22.3_03334 1239962.C943_02790 1.4e-79 304.3 Cytophagia Bacteria 47TNE@768503,4NMRZ@976,COG4585@1,COG4585@2 NA|NA|NA T 7TM diverse intracellular signalling MAG.T22.3_03335 1288963.ADIS_0511 2.2e-55 222.2 Bacteria Bacteria COG2197@1,COG2197@2 NA|NA|NA K response regulator MAG.T22.3_03336 1487953.JMKF01000072_gene3523 4.3e-77 295.4 Oscillatoriales Bacteria 1G1XQ@1117,1H9CT@1150,COG1819@1,COG1819@2 NA|NA|NA CG COGs COG1819 Glycosyl transferase related to UDP-glucuronosyltransferase MAG.T22.3_03337 1121875.KB907558_gene536 1.3e-170 605.9 Flavobacteriia ko:K18372 ko00640,map00640 R10705 RC00460,RC00461 ko00000,ko00001,ko01000 Bacteria 1HXEI@117743,4NGZR@976,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T22.3_03338 1487953.JMKF01000072_gene3523 6.1e-76 291.6 Oscillatoriales Bacteria 1G1XQ@1117,1H9CT@1150,COG1819@1,COG1819@2 NA|NA|NA CG COGs COG1819 Glycosyl transferase related to UDP-glucuronosyltransferase MAG.T22.3_03339 1123276.KB893301_gene4190 8.6e-74 283.9 Cytophagia Bacteria 47YR9@768503,4PPND@976,COG1028@1,COG1028@2 NA|NA|NA IQ Fungal family of unknown function (DUF1776) MAG.T22.3_03340 1239962.C943_02790 2.7e-96 359.8 Cytophagia Bacteria 47TNE@768503,4NMRZ@976,COG4585@1,COG4585@2 NA|NA|NA T 7TM diverse intracellular signalling MAG.T22.3_03342 1288963.ADIS_0509 2.6e-59 235.7 Bacteroidetes 3.2.2.21 ko:K13529,ko:K15051 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 Bacteria 4PPMV@976,COG2169@1,COG2169@2 NA|NA|NA F Helix-turn-helix domain MAG.T22.3_03343 1239962.C943_04197 6.5e-246 856.3 Cytophagia cho GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 ko:K02342,ko:K03703,ko:K03763,ko:K05984 ko00230,ko00240,ko01100,ko03030,ko03420,ko03430,ko03440,map00230,map00240,map01100,map03030,map03420,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 47PIJ@768503,4NEQX@976,COG0322@1,COG0322@2,COG0847@1,COG0847@2 NA|NA|NA L TIGRFAM exonuclease, DNA polymerase III, epsilon subunit family MAG.T22.3_03344 1239962.C943_04195 1.7e-265 921.4 Cytophagia 3.2.1.45 ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 R01498 RC00059,RC00451 ko00000,ko00001,ko01000 GH30 Bacteria 47K24@768503,4NF4C@976,COG5520@1,COG5520@2 NA|NA|NA G Belongs to the glycosyl hydrolase 30 family MAG.T22.3_03345 1347342.BN863_2870 1.1e-07 63.2 Bacteroidetes Bacteria 293H5@1,2ZQZ9@2,4P8S9@976 NA|NA|NA MAG.T22.3_03346 1239962.C943_04193 0.0 1168.3 Cytophagia Bacteria 47K4T@768503,4NFPC@976,COG3250@1,COG3250@2 NA|NA|NA G Belongs to the glycosyl hydrolase 2 family MAG.T22.3_03347 1239962.C943_04192 6.8e-238 829.7 Cytophagia Bacteria 47KUI@768503,4NGDZ@976,COG1082@1,COG1082@2,COG2152@1,COG2152@2 NA|NA|NA G Domain of Unknown Function (DUF1080) MAG.T22.3_03348 1239962.C943_04191 4.4e-263 913.3 Cytophagia Bacteria 47KB4@768503,4NF96@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.3_03349 1239962.C943_04189 2.4e-80 304.7 Cytophagia Bacteria 47Q2D@768503,4NM6B@976,COG2143@1,COG2143@2 NA|NA|NA O Protein of unknown function, DUF255 MAG.T22.3_03350 1239962.C943_04188 7.1e-248 862.8 Cytophagia mnmE GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K03650 R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 Bacteria 47JRR@768503,4NECT@976,COG0486@1,COG0486@2 NA|NA|NA S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 MAG.T22.3_03351 1239962.C943_04141 3.7e-91 340.9 Cytophagia lemA ko:K03744 ko00000 Bacteria 47V0B@768503,4NMP9@976,COG1704@1,COG1704@2 NA|NA|NA S LemA family MAG.T22.3_03352 1239962.C943_04140 1.3e-308 1065.1 Bacteroidetes Bacteria 4NJKC@976,COG4907@1,COG4907@2 NA|NA|NA S Predicted membrane protein (DUF2207) MAG.T22.3_03353 1239962.C943_04139 4.6e-172 610.5 Cytophagia dlgD 1.1.1.130 ko:K08092 ko00040,ko00053,map00040,map00053 R02637,R02639 RC00238 ko00000,ko00001,ko01000 Bacteria 47MHU@768503,4NGVC@976,COG2055@1,COG2055@2 NA|NA|NA C Belongs to the LDH2 MDH2 oxidoreductase family MAG.T22.3_03354 1239962.C943_04138 1.9e-46 191.4 Cytophagia Bacteria 47V9R@768503,4NUEC@976,COG5470@1,COG5470@2 NA|NA|NA S Domain of unknown function (DUF1330) MAG.T22.3_03355 1239962.C943_04137 1.8e-227 795.0 Cytophagia uxaB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009026,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.1.1.17,1.1.1.58 ko:K00009,ko:K00041 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00631 R02555,R02703 RC00085 ko00000,ko00001,ko00002,ko01000 Bacteria 47K47@768503,4NEMT@976,COG0246@1,COG0246@2 NA|NA|NA G PFAM Mannitol dehydrogenase MAG.T22.3_03356 1239962.C943_03064 2.2e-165 588.2 Cytophagia Bacteria 47XPK@768503,4NRIR@976,COG2801@1,COG2801@2 NA|NA|NA L DDE domain MAG.T22.3_03357 1239962.C943_03065 4.8e-67 260.4 Bacteroidetes ko:K07483,ko:K07497 ko00000 Bacteria 4NQ8V@976,COG2963@1,COG2963@2 NA|NA|NA L Pfam Transposase MAG.T22.3_03358 1239962.C943_04135 1.1e-228 798.9 Cytophagia mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 Bacteria 47KX3@768503,4NFXZ@976,COG0482@1,COG0482@2 NA|NA|NA J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 MAG.T22.3_03359 1239962.C943_04134 3.6e-218 763.8 Cytophagia Bacteria 47Y4I@768503,4PM5Q@976,COG1994@1,COG1994@2 NA|NA|NA S PFAM Peptidase family M50 MAG.T22.3_03360 1239962.C943_04133 4.5e-117 427.2 Cytophagia yihX 3.1.3.10,3.8.1.2 ko:K01560,ko:K07025,ko:K20866 ko00010,ko00361,ko00625,ko01100,ko01120,map00010,map00361,map00625,map01100,map01120 R00947,R05287 RC00078,RC00697 ko00000,ko00001,ko01000 Bacteria 47QH7@768503,4NQT8@976,COG1011@1,COG1011@2 NA|NA|NA S TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED MAG.T22.3_03362 1239962.C943_04130 0.0 1582.0 Cytophagia acyII 3.5.1.11,3.5.1.97 ko:K01434,ko:K07116 ko00311,ko01130,map00311,map01130 R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 Bacteria 47KXN@768503,4NEIX@976,COG2366@1,COG2366@2 NA|NA|NA S Penicillin amidase MAG.T22.3_03363 1239962.C943_04129 3.7e-304 1050.0 Cytophagia uxaA 3.1.1.17,4.2.1.7 ko:K01053,ko:K01685 ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129,M00631 R01519,R01540,R02933,R03751 RC00537,RC00543,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47K7S@768503,4NFVQ@976,COG2721@1,COG2721@2 NA|NA|NA G PFAM D-galactarate dehydratase Altronate hydrolase MAG.T22.3_03364 1239962.C943_04128 6.5e-187 659.8 Cytophagia 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 47KKJ@768503,4NFH8@976,COG0524@1,COG0524@2 NA|NA|NA G PFAM PfkB MAG.T22.3_03365 1239962.C943_04127 1.2e-120 439.1 Cytophagia eda 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 47PM4@768503,4NEFY@976,COG0800@1,COG0800@2 NA|NA|NA G PFAM KDPG and KHG aldolase MAG.T22.3_03366 1239962.C943_04126 3.8e-194 684.1 Bacteroidetes dctP Bacteria 4NGV4@976,COG1638@1,COG1638@2 NA|NA|NA G TIGRFAM tripartite ATP-independent periplasmic transporter solute receptor, DctP family MAG.T22.3_03367 1239962.C943_04125 1.6e-77 295.4 Cytophagia ko:K11689 ko02020,map02020 ko00000,ko00001,ko02000 2.A.56.1 Bacteria 47QUK@768503,4NNRW@976,COG3090@1,COG3090@2 NA|NA|NA G transport system, small permease component MAG.T22.3_03368 1239962.C943_04124 2.6e-212 744.6 Cytophagia dctM Bacteria 47NB4@768503,4NE5T@976,COG1593@1,COG1593@2 NA|NA|NA G Tripartite ATP-independent periplasmic transporter, DctM component MAG.T22.3_03369 1239962.C943_04122 3.8e-194 684.1 Cytophagia Bacteria 47NQ3@768503,4NJEQ@976,COG0520@1,COG0520@2 NA|NA|NA E Aminotransferase class-V MAG.T22.3_03370 1239962.C943_04121 5.5e-231 806.6 Cytophagia 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 47NY6@768503,4NIXW@976,COG0412@1,COG0412@2 NA|NA|NA Q COG COG1073 Hydrolases of the alpha beta superfamily MAG.T22.3_03371 866536.Belba_3312 5e-186 657.5 Cytophagia Bacteria 47M00@768503,4NHFU@976,COG3386@1,COG3386@2 NA|NA|NA G Domain of unknown function (DUF4394) MAG.T22.3_03373 1239962.C943_04119 0.0 1810.0 Cytophagia ko:K14054 ko00000 Bacteria 47N2M@768503,4NGIE@976,COG2866@1,COG2866@2 NA|NA|NA E Zinc carboxypeptidase MAG.T22.3_03374 1239962.C943_04118 6e-211 740.0 Cytophagia Bacteria 47NKX@768503,4NG6V@976,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T22.3_03375 1239962.C943_04117 8.9e-212 742.7 Cytophagia Bacteria 47K88@768503,4NGR9@976,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases MAG.T22.3_03377 1239962.C943_04116 1.2e-109 402.5 Cytophagia ko:K11068 ko00000,ko02042 Bacteria 47PJI@768503,4NM95@976,COG1272@1,COG1272@2 NA|NA|NA S TIGRFAM channel protein, hemolysin III family MAG.T22.3_03378 1239962.C943_04115 3.4e-36 157.1 Cytophagia Bacteria 2EQZ1@1,33IIQ@2,47T71@768503,4NXHA@976 NA|NA|NA MAG.T22.3_03379 1239962.C943_04114 1.2e-71 275.8 Cytophagia rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47PY1@768503,4NNRP@976,COG0359@1,COG0359@2 NA|NA|NA J binds to the 23S rRNA MAG.T22.3_03380 1239962.C943_04113 1.1e-39 168.7 Cytophagia rpsR GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47R23@768503,4NSAR@976,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit MAG.T22.3_03381 1239962.C943_04112 4.6e-61 240.4 Cytophagia rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 47QQD@768503,4NQ9W@976,COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA MAG.T22.3_03382 1239962.C943_04111 6.9e-159 566.6 Cytophagia ko:K09892 ko00000,ko03036 Bacteria 47MGD@768503,4NHAC@976,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation MAG.T22.3_03383 1239962.C943_04110 3.6e-100 370.9 Cytophagia tpm 2.1.1.67 ko:K00569 ko00983,map00983 R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 Bacteria 47Q0R@768503,4NNNE@976,COG0500@1,COG0500@2 NA|NA|NA Q Thiopurine S-methyltransferase (TPMT) MAG.T22.3_03384 1239962.C943_04109 5.8e-138 496.9 Cytophagia Bacteria 47N8Y@768503,4NG1S@976,COG4122@1,COG4122@2 NA|NA|NA S Methyltransferase domain MAG.T22.3_03385 1239962.C943_04107 2.1e-125 455.3 Cytophagia ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Bacteria 47JRB@768503,4NE2B@976,COG0692@1,COG0692@2 NA|NA|NA L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine MAG.T22.3_03386 1239962.C943_04105 1.2e-205 722.2 Cytophagia 1.1.99.28 ko:K00118 ko00000,ko01000 Bacteria 47JGE@768503,4NE75@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase domain protein MAG.T22.3_03387 1239962.C943_04103 2e-64 251.5 Cytophagia Bacteria 47QKJ@768503,4NQIE@976,COG0346@1,COG0346@2 NA|NA|NA E glyoxalase MAG.T22.3_03388 1239962.C943_04102 9.8e-93 346.3 Cytophagia Bacteria 47PX0@768503,4NN4Z@976,COG4430@1,COG4430@2 NA|NA|NA S Bacteriocin-protection, YdeI or OmpD-Associated MAG.T22.3_03389 1239962.C943_04101 2.8e-208 731.1 Bacteroidetes ko:K06985 ko04112,map04112 ko00000,ko00001 Bacteria 4NYMC@976,COG3577@1,COG3577@2 NA|NA|NA S Aspartyl protease MAG.T22.3_03390 1239962.C943_04100 2.1e-175 621.7 Cytophagia 3.1.1.1 ko:K03928 ko00000,ko01000 Bacteria 47JR1@768503,4NHPY@976,COG1647@1,COG1647@2 NA|NA|NA E Alpha/beta hydrolase family MAG.T22.3_03391 1239962.C943_04099 7.7e-310 1068.9 Cytophagia Bacteria 47KZX@768503,4NFDJ@976,COG2234@1,COG2234@2 NA|NA|NA S PA domain MAG.T22.3_03392 1189612.A33Q_1687 4.6e-219 767.3 Cytophagia Bacteria 2EY5E@1,33RE6@2,47TZC@768503,4PAKQ@976 NA|NA|NA S Glycosyltransferase WbsX MAG.T22.3_03394 1239962.C943_04096 2.8e-182 644.4 Cytophagia 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 47JQN@768503,4NEI8@976,COG3958@1,COG3958@2 NA|NA|NA G PFAM Transketolase, C-terminal domain MAG.T22.3_03395 1239962.C943_04095 2.9e-159 567.8 Cytophagia tktA 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 47JJD@768503,4NDWK@976,COG3959@1,COG3959@2 NA|NA|NA G PFAM Transketolase, thiamine diphosphate binding domain MAG.T22.3_03396 1239962.C943_04094 1.2e-79 302.4 Cytophagia bcp GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 ko:K03564 ko00000,ko01000 Bacteria 47PUA@768503,4NNGK@976,COG1225@1,COG1225@2 NA|NA|NA O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MAG.T22.3_03397 1239962.C943_04093 0.0 1211.4 Cytophagia Bacteria 47JZB@768503,4NED7@976,COG0739@1,COG0739@2 NA|NA|NA M PFAM Peptidase family M23 MAG.T22.3_03398 1239962.C943_04092 2.1e-111 408.3 Cytophagia ycgM Bacteria 47MHB@768503,4NGCT@976,COG0179@1,COG0179@2 NA|NA|NA Q PFAM fumarylacetoacetate (FAA) hydrolase MAG.T22.3_03399 1239962.C943_04091 2.3e-122 444.9 Cytophagia Bacteria 47XIF@768503,4NMAD@976,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C terminal MAG.T22.3_03400 1239962.C943_04090 4.1e-249 867.1 Cytophagia Bacteria 47YET@768503,4NI8C@976,COG0642@1,COG2205@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain MAG.T22.3_03401 1239962.C943_04088 1.1e-120 439.5 Cytophagia Bacteria 28J3Q@1,32URP@2,47R3P@768503,4NT50@976 NA|NA|NA S Protein of unknown function (Porph_ging) MAG.T22.3_03402 1239962.C943_01752 0.0 1814.7 Cytophagia Bacteria 47JEF@768503,4NF88@976,COG1629@1,COG1629@2 NA|NA|NA P Outer membrane protein beta-barrel family MAG.T22.3_03403 1239962.C943_01747 0.0 1145.6 Cytophagia Bacteria 47TV8@768503,4NFMV@976,COG1574@1,COG1574@2 NA|NA|NA S Amidohydrolase family MAG.T22.3_03404 1239962.C943_01746 9.6e-126 456.4 Cytophagia Bacteria 47KQ2@768503,4NJ3A@976,COG3279@1,COG3279@2 NA|NA|NA KT PFAM LytTr DNA-binding region MAG.T22.3_03405 1239962.C943_01744 7.6e-115 419.9 Cytophagia Bacteria 2DBUE@1,2ZB5Q@2,47NTR@768503,4NM7Y@976 NA|NA|NA MAG.T22.3_03406 1239962.C943_01743 4.3e-155 553.9 Cytophagia Bacteria 47P9T@768503,4NKZ6@976,COG2304@1,COG2304@2 NA|NA|NA E CarboxypepD_reg-like domain MAG.T22.3_03408 1239962.C943_01741 2.4e-150 538.1 Cytophagia sseA 2.8.1.1,2.8.1.11,2.8.1.2 ko:K01011,ko:K21028 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 R01931,R03105,R03106,R07461 RC00214 ko00000,ko00001,ko01000 Bacteria 47PN4@768503,4NF85@976,COG2897@1,COG2897@2 NA|NA|NA P Rhodanese Homology Domain MAG.T22.3_03410 1239962.C943_01739 2.2e-167 594.7 Cytophagia xynZ 3.1.2.12 ko:K01070 ko00680,ko01120,ko01200,map00680,map01120,map01200 R00527 RC00167,RC00320 ko00000,ko00001,ko01000 CE1 Bacteria 47M5Z@768503,4NGI8@976,COG0627@1,COG0627@2 NA|NA|NA S Putative esterase MAG.T22.3_03411 1239962.C943_01737 0.0 1713.4 Cytophagia Bacteria 47P17@768503,4PKFW@976,COG4206@1,COG4206@2 NA|NA|NA H Outer membrane protein beta-barrel family MAG.T22.3_03412 1239962.C943_01736 5.3e-181 640.2 Cytophagia pfkA 2.7.1.11,2.7.1.90 ko:K00850,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Bacteria 47M49@768503,4NF8F@976,COG0205@1,COG0205@2 NA|NA|NA G Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis MAG.T22.3_03413 1239962.C943_01735 8.4e-63 246.1 Cytophagia mgsA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 2.7.1.24,4.2.3.3 ko:K00859,ko:K01734 ko00640,ko00770,ko01100,ko01120,map00640,map00770,map01100,map01120 M00120 R00130,R01016 RC00002,RC00078,RC00424 ko00000,ko00001,ko00002,ko01000 iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992 Bacteria 47PW5@768503,4NQJ9@976,COG1803@1,COG1803@2 NA|NA|NA G MGS-like domain MAG.T22.3_03414 1239962.C943_01734 3.9e-58 230.7 Cytophagia mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 47R3N@768503,4NQ49@976,COG1970@1,COG1970@2 NA|NA|NA M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell MAG.T22.3_03415 1239962.C943_01733 8.1e-80 303.1 Cytophagia Bacteria 2DPE1@1,331PZ@2,47R28@768503,4NV5C@976 NA|NA|NA MAG.T22.3_03416 1123057.P872_24575 5.5e-22 110.5 Cytophagia Bacteria 2DYS9@1,34AWN@2,47VWN@768503,4P6QB@976 NA|NA|NA MAG.T22.3_03417 1239962.C943_01731 2.3e-72 278.1 Cytophagia ko:K03088 ko00000,ko03021 Bacteria 47N5B@768503,4NMC0@976,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily MAG.T22.3_03418 1239962.C943_01730 1.5e-161 575.5 Cytophagia Bacteria 47NF9@768503,4NFSG@976,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein MAG.T22.3_03419 1239962.C943_01728 1.9e-246 858.2 Cytophagia Bacteria 47MXC@768503,4NEVQ@976,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein MAG.T22.3_03420 1239962.C943_01727 8.5e-182 642.9 Bacteroidetes Bacteria 4NNVW@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.3_03421 1239962.C943_01726 1.4e-127 462.2 Cytophagia 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 Bacteria 47TGS@768503,4NTKJ@976,COG2227@1,COG2227@2 NA|NA|NA H Nodulation protein S (NodS) MAG.T22.3_03422 1239962.C943_01725 0.0 1531.9 Cytophagia Bacteria 47ME6@768503,4NEE5@976,COG4485@1,COG4485@2 NA|NA|NA S PFAM Bacterial membrane protein YfhO MAG.T22.3_03423 1239962.C943_01724 1.9e-242 844.7 Cytophagia ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 47MYD@768503,4NDZ2@976,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY MAG.T22.3_03424 1239962.C943_01723 1.4e-193 682.2 Cytophagia dprA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044424,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 ko:K04096 ko00000 Bacteria 47M2T@768503,4NF7T@976,COG0758@1,COG0758@2 NA|NA|NA LU TIGRFAM DNA protecting protein DprA MAG.T22.3_03425 1239962.C943_01722 1.2e-58 232.3 Cytophagia ycgE ko:K19591,ko:K22491 M00769 ko00000,ko00002,ko01504,ko03000 Bacteria 47R35@768503,4NSBD@976,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance MAG.T22.3_03426 1239962.C943_01721 2.6e-46 191.4 Bacteroidetes 5.1.3.32 ko:K03534 R10819 RC00563 ko00000,ko01000 Bacteria 4NQAA@976,COG3254@1,COG3254@2 NA|NA|NA S mutarotase MAG.T22.3_03427 1239962.C943_01720 6.4e-226 790.0 Cytophagia yqiK ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 Bacteria 47TCM@768503,4NIH3@976,COG2268@1,COG2268@2 NA|NA|NA S prohibitin homologues MAG.T22.3_03428 1239962.C943_01719 4.5e-92 344.0 Cytophagia Bacteria 29F7N@1,3025B@2,47V4W@768503,4NNR8@976 NA|NA|NA MAG.T22.3_03429 1239962.C943_01718 0.0 1984.5 Bacteroidetes Bacteria 4NGZV@976,COG3209@1,COG3209@2,COG3291@1,COG3291@2 NA|NA|NA U IgGFc binding protein MAG.T22.3_03430 1239962.C943_01717 0.0 1973.4 Cytophagia Bacteria 47TBR@768503,4NGZV@976,COG3209@1,COG3209@2,COG3291@1,COG3291@2 NA|NA|NA M C-terminal domain of CHU protein family MAG.T22.3_03431 1239962.C943_01716 6.1e-188 663.3 Cytophagia galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 47JM5@768503,4NEM9@976,COG1087@1,COG1087@2 NA|NA|NA M PFAM NAD dependent epimerase dehydratase family MAG.T22.3_03434 1239962.C943_01714 6e-174 616.7 Cytophagia accA GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iAF1260.b0185,iBWG_1329.BWG_0177,iEC55989_1330.EC55989_0179,iECDH10B_1368.ECDH10B_0165,iECDH1ME8569_1439.ECDH1ME8569_0178,iECED1_1282.ECED1_0191,iECH74115_1262.ECH74115_0195,iECIAI1_1343.ECIAI1_0185,iECNA114_1301.ECNA114_0175,iECO111_1330.ECO111_0186,iECO26_1355.ECO26_0187,iECP_1309.ECP_0193,iECSE_1348.ECSE_0184,iECSF_1327.ECSF_0200,iECSP_1301.ECSP_0184,iECW_1372.ECW_m0181,iECs_1301.ECs0187,iEKO11_1354.EKO11_3733,iEcDH1_1363.EcDH1_3418,iEcE24377_1341.EcE24377A_0189,iEcHS_1320.EcHS_A0187,iG2583_1286.G2583_0188,iJN678.accA,iJN746.PP_1607,iJO1366.b0185,iJR904.b0185,iLF82_1304.LF82_0008,iNRG857_1313.NRG857_00945,iSDY_1059.SDY_0201,iSFV_1184.SFV_0168,iSF_1195.SF0175,iSFxv_1172.SFxv_0185,iS_1188.S0178,iUMNK88_1353.UMNK88_190,iWFL_1372.ECW_m0181,iY75_1357.Y75_RS00935,iZ_1308.Z0197 Bacteria 47JPY@768503,4NEVU@976,COG0825@1,COG0825@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA MAG.T22.3_03435 1239962.C943_01713 2.9e-156 557.8 Cytophagia ytnP Bacteria 47JCR@768503,4NE98@976,COG0491@1,COG0491@2 NA|NA|NA S PFAM Metallo-beta-lactamase superfamily MAG.T22.3_03436 1239962.C943_01712 2.2e-145 521.5 Cytophagia ko:K07001 ko00000 Bacteria 47JZ5@768503,4NERH@976,COG1752@1,COG1752@2 NA|NA|NA S esterase of the alpha-beta hydrolase superfamily MAG.T22.3_03437 1239962.C943_01711 1.6e-105 388.7 Cytophagia plsC2 Bacteria 47Q72@768503,4NNG7@976,COG0204@1,COG0204@2 NA|NA|NA I Acyltransferase MAG.T22.3_03438 1239962.C943_01710 8.9e-43 180.3 Cytophagia Bacteria 2EVW6@1,33P9V@2,47T0U@768503,4NZIN@976 NA|NA|NA MAG.T22.3_03439 1239962.C943_01708 5.4e-129 467.2 Cytophagia ko:K03453 ko00000 2.A.28 Bacteria 47QUN@768503,4NEIM@976,COG0385@1,COG0385@2 NA|NA|NA S PFAM Sodium Bile acid symporter family MAG.T22.3_03440 1239962.C943_01707 9.6e-116 422.9 Cytophagia truC GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.26 ko:K06175 ko00000,ko01000,ko03016 Bacteria 47MQ7@768503,4NGB1@976,COG0564@1,COG0564@2 NA|NA|NA J PFAM RNA pseudouridylate synthase MAG.T22.3_03441 1239962.C943_01706 1.7e-290 1004.6 Cytophagia Bacteria 47JPR@768503,4NF48@976,COG2939@1,COG2939@2 NA|NA|NA E PFAM Serine carboxypeptidase MAG.T22.3_03442 1239962.C943_01704 1.8e-184 651.7 Cytophagia Bacteria 28KF4@1,2ZA1C@2,47UXU@768503,4NNRR@976 NA|NA|NA MAG.T22.3_03443 1239962.C943_01703 3.8e-96 357.5 Cytophagia ftnA GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008199,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033554,GO:0042221,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0097577,GO:0098771 1.16.3.2 ko:K02217,ko:K02255 ko00000,ko01000 Bacteria 47Q0N@768503,4NGS7@976,COG1528@1,COG1528@2 NA|NA|NA P Iron-storage protein MAG.T22.3_03445 1239962.C943_01700 9.2e-261 905.6 Cytophagia Bacteria 47JH2@768503,4NGGS@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain MAG.T22.3_03447 1239962.C943_01698 3.2e-98 364.4 Cytophagia ydaF_1 Bacteria 47X4U@768503,4NMB7@976,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain MAG.T22.3_03448 1239962.C943_01697 8.1e-210 736.1 Cytophagia pat 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 47PVQ@768503,4NEW8@976,COG0079@1,COG0079@2 NA|NA|NA E Aminotransferase class-V MAG.T22.3_03449 1239962.C943_01696 1e-126 459.5 Cytophagia Bacteria 28NAV@1,2ZBEH@2,47T10@768503,4NJGP@976 NA|NA|NA MAG.T22.3_03450 1239962.C943_01695 2e-191 674.9 Cytophagia yghZ ko:K19265 ko00000,ko01000 Bacteria 47N0Q@768503,4NFCN@976,COG0667@1,COG0667@2 NA|NA|NA C PFAM Aldo keto reductase family MAG.T22.3_03451 1239962.C943_01694 1.5e-229 802.0 Cytophagia Bacteria 47MN0@768503,4NEUI@976,COG1288@1,COG1288@2 NA|NA|NA S C4-dicarboxylate anaerobic carrier MAG.T22.3_03452 1239962.C943_01693 1.2e-255 888.6 Cytophagia Bacteria 47N3G@768503,4NGC0@976,COG2072@1,COG2072@2 NA|NA|NA P Flavin-binding monooxygenase-like MAG.T22.3_03453 1239962.C943_01692 9e-127 459.5 Cytophagia cobB ko:K12410 ko00000,ko01000 Bacteria 47KMH@768503,4NE9Q@976,COG0846@1,COG0846@2 NA|NA|NA K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form MAG.T22.3_03454 1239962.C943_01691 0.0 1469.9 Cytophagia topA GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 47K7C@768503,4NF9S@976,COG0550@1,COG0550@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone MAG.T22.3_03455 1239962.C943_01690 3.1e-46 191.4 Bacteria sixA ko:K08296 ko00000,ko01000 Bacteria COG2062@1,COG2062@2 NA|NA|NA T phosphohistidine phosphatase, SixA MAG.T22.3_03456 1239962.C943_01689 3.5e-272 943.7 Cytophagia Bacteria 47M7Q@768503,4NDWS@976,COG0810@1,COG0810@2,COG4219@1,COG4219@2 NA|NA|NA KMT PFAM BlaR1 peptidase M56 MAG.T22.3_03457 1239962.C943_01688 1e-60 239.2 Cytophagia Bacteria 47Q5Z@768503,4NNVM@976,COG3682@1,COG3682@2 NA|NA|NA K PFAM Penicillinase repressor MAG.T22.3_03458 866536.Belba_3064 3.3e-135 487.6 Cytophagia desC 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 R02222 RC00917 ko00000,ko00001,ko01000,ko01004 Bacteria 47KJ0@768503,4NE0I@976,COG1398@1,COG1398@2 NA|NA|NA I fatty acid desaturase MAG.T22.3_03459 1239962.C943_01686 5e-44 183.7 Cytophagia yvlD ko:K08972 ko00000 Bacteria 47S20@768503,4NT2I@976,COG1950@1,COG1950@2 NA|NA|NA S PFAM Membrane protein of MAG.T22.3_03460 1239962.C943_01685 1.4e-54 219.2 Bacteria Bacteria COG2865@1,COG2865@2 NA|NA|NA MAG.T22.3_03461 1239962.C943_01684 1.5e-96 359.0 Cytophagia Bacteria 28Q4Y@1,2ZCN1@2,47P9K@768503,4NRPX@976 NA|NA|NA MAG.T22.3_03462 1239962.C943_01683 3.9e-146 524.2 Cytophagia acuC Bacteria 47KIZ@768503,4NF3X@976,COG0123@1,COG0123@2 NA|NA|NA BQ PFAM Histone deacetylase domain MAG.T22.3_03463 1239962.C943_01682 6.3e-98 363.6 Cytophagia ko:K06142 ko00000 Bacteria 47MRT@768503,4NQGG@976,COG2825@1,COG2825@2 NA|NA|NA M PFAM Outer membrane chaperone Skp (OmpH) MAG.T22.3_03464 1239962.C943_01681 5.4e-186 656.8 Cytophagia dys 2.5.1.46 ko:K00809 ko00000,ko01000 Bacteria 47M06@768503,4NEZ0@976,COG1899@1,COG1899@2 NA|NA|NA O Deoxyhypusine synthase MAG.T22.3_03465 1239962.C943_01680 6e-289 999.6 Cytophagia Bacteria 47MW3@768503,4NEND@976,COG2885@1,COG2885@2 NA|NA|NA M Belongs to the ompA family MAG.T22.3_03466 1239962.C943_01679 8.3e-101 373.2 Bacteroidetes ko:K02529 ko00000,ko03000 Bacteria 4NDW6@976,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein LacI transcriptional regulator MAG.T22.3_03467 1239962.C943_01679 2.2e-45 188.0 Bacteroidetes ko:K02529 ko00000,ko03000 Bacteria 4NDW6@976,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein LacI transcriptional regulator MAG.T22.3_03469 1239962.C943_00961 0.0 1251.9 Cytophagia Bacteria 47PQC@768503,4NMB8@976,COG1361@1,COG1361@2 NA|NA|NA M Domain of unknown function DUF11 MAG.T22.3_03470 1239962.C943_00962 0.0 1477.2 Cytophagia Bacteria 47UJH@768503,4NE6G@976,COG2885@1,COG2885@2 NA|NA|NA M Belongs to the ompA family MAG.T22.3_03472 1239962.C943_00964 2.1e-70 271.6 Bacteroidetes osmC ko:K04063 ko00000 Bacteria 4NQKB@976,COG1764@1,COG1764@2 NA|NA|NA O redox protein regulator of disulfide bond formation MAG.T22.3_03473 1239962.C943_00965 1.2e-112 412.5 Bacteroidetes Bacteria 2AECJ@1,31473@2,4NZDM@976 NA|NA|NA S Ion channel MAG.T22.3_03475 1239962.C943_00966 1.2e-264 918.7 Cytophagia cvrA ko:K03316,ko:K11105 ko00000,ko02000 2.A.36,2.A.36.6 Bacteria 47P2K@768503,4NFNS@976,COG3263@1,COG3263@2 NA|NA|NA P TrkA-C domain MAG.T22.3_03476 1239962.C943_00967 2.2e-67 261.5 Cytophagia Bacteria 29AZZ@1,2ZXYX@2,47Q19@768503,4NP6M@976 NA|NA|NA MAG.T22.3_03477 1239962.C943_00968 2.4e-53 214.5 Cytophagia ypjD 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 Bacteria 47QEV@768503,4NQ3H@976,COG1694@1,COG1694@2 NA|NA|NA S PFAM MazG nucleotide pyrophosphohydrolase MAG.T22.3_03480 1239962.C943_01946 1.8e-206 724.9 Cytophagia idh Bacteria 47KZS@768503,4NEC6@976,COG0673@1,COG0673@2 NA|NA|NA S PFAM Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.3_03482 1239962.C943_01950 8.6e-44 182.6 Bacteroidetes yjdJ ko:K06975 ko00000 Bacteria 4NUS6@976,COG2388@1,COG2388@2 NA|NA|NA S gnat family MAG.T22.3_03483 1239962.C943_01951 3.2e-245 854.0 Cytophagia Bacteria 47KER@768503,4NIC8@976,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase MAG.T22.3_03484 1239962.C943_01952 9e-130 469.5 Cytophagia lytT ko:K02477 ko00000,ko02022 Bacteria 47N62@768503,4NFWA@976,COG3279@1,COG3279@2 NA|NA|NA T Response regulator of the LytR AlgR family MAG.T22.3_03485 1239962.C943_01953 3.2e-187 661.0 Cytophagia Bacteria 47V23@768503,4NRRA@976,COG2972@1,COG2972@2 NA|NA|NA T Histidine kinase MAG.T22.3_03486 1239962.C943_01955 1.4e-153 548.9 Cytophagia MA20_14845 4.2.1.141 ko:K14259 ko00040,map00040 R09186 RC00429 ko00000,ko00001,ko01000 Bacteria 47MQU@768503,4NGTH@976,COG3970@1,COG3970@2 NA|NA|NA S PFAM fumarylacetoacetate (FAA) hydrolase MAG.T22.3_03487 1239962.C943_01957 4.1e-52 211.1 Cytophagia ble Bacteria 47RXX@768503,4NQRN@976,COG0346@1,COG0346@2 NA|NA|NA E bleomycin resistance protein MAG.T22.3_03488 1239962.C943_01959 0.0 1673.3 Cytophagia ppc 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 Bacteria 47NF0@768503,4NFC0@976,COG2352@1,COG2352@2 NA|NA|NA C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle MAG.T22.3_03489 1123057.P872_14650 1e-122 446.4 Cytophagia amiA 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria 47M2P@768503,4NGKC@976,COG0860@1,COG0860@2 NA|NA|NA M N-acetylmuramoyl-L-alanine amidase MAG.T22.3_03490 1239962.C943_01961 0.0 1776.1 Cytophagia Bacteria 47JIS@768503,4NFWD@976,COG1452@1,COG1452@2 NA|NA|NA M Organic solvent tolerance protein OstA MAG.T22.3_03491 991.IW20_16135 7e-10 71.2 Flavobacterium Bacteria 1I34P@117743,2NWCZ@237,4NR9K@976,COG3637@1,COG3637@2 NA|NA|NA M Outer membrane protein beta-barrel domain MAG.T22.3_03492 1121104.AQXH01000001_gene1458 3.1e-28 132.1 Sphingobacteriia Bacteria 1IT9D@117747,4NF5P@976,COG2197@1,COG2197@2 NA|NA|NA T helix_turn_helix, Lux Regulon MAG.T22.3_03493 1121904.ARBP01000004_gene1090 1.2e-21 110.5 Bacteroidetes Bacteria 2C5YW@1,333G7@2,4P64P@976 NA|NA|NA S Probable zinc-ribbon domain MAG.T22.3_03495 1239962.C943_01963 0.0 1092.4 Cytophagia 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 Bacteria 47KS8@768503,4NENG@976,COG0028@1,COG0028@2 NA|NA|NA EH TIGRFAM acetolactate synthase, large subunit, biosynthetic type MAG.T22.3_03496 1239962.C943_01964 8.1e-196 689.5 Bacteroidetes ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 4NGHH@976,COG0739@1,COG0739@2 NA|NA|NA M peptidase M23 MAG.T22.3_03497 1239962.C943_01965 0.0 1644.0 Cytophagia alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 47KKH@768503,4NFHW@976,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain MAG.T22.3_03498 1239962.C943_01966 2.7e-277 960.7 Cytophagia gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 ko:K01876,ko:K02434 ko00970,ko01100,map00970,map01100 M00359,M00360 R03905,R04212,R05577 RC00010,RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 47K7E@768503,4NF3B@976,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) MAG.T22.3_03499 1239962.C943_01967 2.3e-204 718.0 Cytophagia Bacteria 47JZP@768503,4NEX3@976,COG0526@1,COG0526@2 NA|NA|NA O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MAG.T22.3_03500 1239962.C943_01968 1.3e-68 265.8 Cytophagia Bacteria 2CD9I@1,347JG@2,47W2V@768503,4P626@976 NA|NA|NA MAG.T22.3_03501 1239962.C943_01969 7.1e-101 373.2 Cytophagia Bacteria 28N54@1,2ZBAD@2,47PNE@768503,4NN5P@976 NA|NA|NA MAG.T22.3_03502 1239962.C943_01970 3e-161 574.3 Cytophagia Bacteria 28Y2X@1,2ZJYG@2,47PI8@768503,4NN0R@976 NA|NA|NA MAG.T22.3_03503 1239962.C943_01971 1.9e-227 795.8 Cytophagia nopM1-1 ko:K13791,ko:K15353 ko05131,ko05132,map05131,map05132 ko00000,ko00001 Bacteria 47NN3@768503,4NHJ3@976,COG4886@1,COG4886@2 NA|NA|NA S Leucine-rich repeat (LRR) protein MAG.T22.3_03504 1239962.C943_01974 3.5e-126 457.6 Cytophagia yhgD GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 ko:K03577,ko:K09017 M00647 ko00000,ko00002,ko03000 Bacteria 47RD7@768503,4NTB4@976,COG1309@1,COG1309@2 NA|NA|NA K PFAM Bacterial regulatory proteins, tetR family MAG.T22.3_03506 1239962.C943_01976 1.7e-243 848.2 Cytophagia tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 47JXG@768503,4NF19@976,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) MAG.T22.3_03507 1239962.C943_01981 0.0 1172.1 Cytophagia 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 Bacteria 47MKS@768503,4NG3X@976,COG0405@1,COG0405@2 NA|NA|NA E Gamma-glutamyltranspeptidase MAG.T22.3_03508 1239962.C943_01982 6.5e-207 726.5 Cytophagia Bacteria 2DBXN@1,2ZBQR@2,47PK0@768503,4NN54@976 NA|NA|NA MAG.T22.3_03509 1239962.C943_01983 6.3e-225 786.6 Cytophagia deaD Bacteria 47M80@768503,4NEVI@976,COG0513@1,COG0513@2 NA|NA|NA L Belongs to the DEAD box helicase family MAG.T22.3_03510 1239962.C943_01984 4.7e-235 820.1 Cytophagia Bacteria 47JBV@768503,4NHJN@976,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T22.3_03511 1239962.C943_01985 2.2e-216 758.1 Cytophagia hemY Bacteria 47KG9@768503,4NEPC@976,COG1232@1,COG1232@2 NA|NA|NA H PFAM Flavin containing amine oxidoreductase MAG.T22.3_03512 1239962.C943_01986 5.2e-251 873.2 Cytophagia 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 R05692 RC01014 ko00000,ko00001,ko01000 Bacteria 47MFP@768503,4NEJF@976,COG0702@1,COG0702@2 NA|NA|NA GM epimerase MAG.T22.3_03513 1239962.C943_01987 7e-306 1055.8 Cytophagia ggt 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 Bacteria 47KUQ@768503,4NF2H@976,COG0405@1,COG0405@2 NA|NA|NA E PFAM Gamma-glutamyltranspeptidase MAG.T22.3_03514 1239962.C943_01988 0.0 1511.9 Cytophagia ptpA_1 Bacteria 47JEZ@768503,4NF70@976,COG0823@1,COG0823@2,COG1506@1,COG1506@2 NA|NA|NA EU Peptidase S9, prolyl oligopeptidase active site domain protein MAG.T22.3_03515 1239962.C943_01989 5.2e-56 223.4 Cytophagia Bacteria 47VHJ@768503,4P4EM@976,COG2198@1,COG2198@2 NA|NA|NA T Histidine kinase MAG.T22.3_03516 1239962.C943_01991 2.9e-84 317.8 Cytophagia Bacteria 2AUDP@1,31K1P@2,47Q75@768503,4NRCQ@976 NA|NA|NA S Protein of unknown function (DUF2452) MAG.T22.3_03517 1239962.C943_01992 1.6e-122 445.3 Cytophagia Bacteria 2EB2C@1,33537@2,47SGN@768503,4NWPB@976 NA|NA|NA MAG.T22.3_03519 1239962.C943_01993 2.3e-113 414.8 Cytophagia dck Bacteria 47P9Q@768503,4NFA8@976,COG1428@1,COG1428@2 NA|NA|NA F deoxynucleoside kinase MAG.T22.3_03520 1239962.C943_01994 1.4e-159 568.9 Cytophagia hbdA 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 Bacteria 47NRU@768503,4NGU8@976,COG1250@1,COG1250@2 NA|NA|NA I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain MAG.T22.3_03521 1239962.C943_01995 2.4e-150 538.1 Cytophagia cvfB ko:K00243 ko00000 Bacteria 47KDR@768503,4NGS6@976,COG2996@1,COG2996@2 NA|NA|NA S S1 domain MAG.T22.3_03522 1239962.C943_01996 2.5e-64 251.1 Cytophagia arsC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 ko:K00537 ko00000,ko01000 Bacteria 47SWP@768503,4NXD1@976,COG1393@1,COG1393@2 NA|NA|NA P ArsC family MAG.T22.3_03523 1239962.C943_01997 5.8e-88 330.1 Cytophagia XK27_05000 ko:K06940 ko00000 Bacteria 47QHT@768503,4NJH9@976,COG0727@1,COG0727@2 NA|NA|NA S Putative zinc- or iron-chelating domain MAG.T22.3_03524 1239962.C943_01998 3.6e-171 607.4 Cytophagia 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 47NRJ@768503,4NFZ1@976,COG1940@1,COG1940@2 NA|NA|NA GK PFAM ROK family MAG.T22.3_03525 1239962.C943_01999 2e-64 251.9 Cytophagia Bacteria 2FFXU@1,347UR@2,47VT6@768503,4P6G1@976 NA|NA|NA MAG.T22.3_03526 1239962.C943_02000 2.5e-109 401.4 Bacteroidetes Bacteria 29TMV@1,30EVG@2,4NNPM@976 NA|NA|NA MAG.T22.3_03527 1239962.C943_02001 0.0 1432.9 Cytophagia ko:K02014 ko00000,ko02000 1.B.14 Bacteria 47JDS@768503,4PKF2@976,COG4206@1,COG4206@2 NA|NA|NA H TonB-dependent Receptor Plug MAG.T22.3_03528 1239962.C943_02003 3.8e-84 317.4 Cytophagia Bacteria 47RZ6@768503,4NNXM@976,COG2050@1,COG2050@2 NA|NA|NA Q Domain of unknown function (DUF4442) MAG.T22.3_03529 1239962.C943_02004 4e-150 537.3 Cytophagia Bacteria 47JGC@768503,4NE0J@976,COG0501@1,COG0501@2 NA|NA|NA O PFAM Peptidase family M48 MAG.T22.3_03530 1239962.C943_02005 2.8e-103 381.3 Cytophagia pncA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 ko:K08281,ko:K12132 ko00760,ko01100,map00760,map01100 R01268 RC00100 ko00000,ko00001,ko01000,ko01001 iE2348C_1286.E2348C_1895,iECs_1301.ECs2475,iZ_1308.Z2802 Bacteria 47PIR@768503,4NKPP@976,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family MAG.T22.3_03531 1239962.C943_02006 9e-121 439.5 Cytophagia Bacteria 47JGU@768503,4NJB3@976,COG2067@1,COG2067@2 NA|NA|NA I Protein of unknown function (DUF2490) MAG.T22.3_03532 1239962.C943_02007 1.4e-200 705.3 Cytophagia Bacteria 47TE5@768503,4NG13@976,COG4772@1,COG4772@2 NA|NA|NA P Type IX secretion system membrane protein PorP/SprF MAG.T22.3_03533 1239962.C943_02008 0.0 6355.4 Cytophagia Bacteria 47MNQ@768503,4NDZC@976,COG3209@1,COG3209@2,COG3291@1,COG3291@2 NA|NA|NA O SprB repeat MAG.T22.3_03534 1239962.C943_02010 1.3e-73 282.3 Bacteria greA ko:K03624 ko00000,ko03021 Bacteria COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus MAG.T22.3_03535 1239962.C943_02012 1.7e-134 485.3 Cytophagia ko:K02066 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 47N59@768503,4NEZ8@976,COG0767@1,COG0767@2 NA|NA|NA Q ABC-type transport system involved in resistance to organic solvents permease component MAG.T22.3_03536 1239962.C943_02013 1.2e-132 479.2 Cytophagia mkl ko:K02065 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 47NIJ@768503,4NETJ@976,COG1127@1,COG1127@2 NA|NA|NA Q ABC transporter MAG.T22.3_03537 1239962.C943_02014 1.5e-164 585.5 Cytophagia ttg2C ko:K02067 ko02010,map02010 M00210,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 47T9B@768503,4NGHE@976,COG1463@1,COG1463@2 NA|NA|NA Q MlaD protein MAG.T22.3_03538 1239962.C943_02015 1.1e-99 369.4 Bacteria ppgK 2.7.1.2,2.7.1.63,5.3.1.9 ko:K00845,ko:K00886,ko:K01810 ko00010,ko00030,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114,M00549 R00299,R01600,R01786,R02187,R02189,R02739,R02740,R03321 RC00002,RC00017,RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria COG1940@1,COG1940@2 NA|NA|NA GK ROK family MAG.T22.3_03539 1239962.C943_02016 4.7e-191 674.1 Bacteroidetes 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 4NGDB@976,COG3049@1,COG3049@2 NA|NA|NA M Choloylglycine hydrolase MAG.T22.3_03542 1239962.C943_02018 4.7e-78 297.0 Cytophagia msrB 1.8.4.11,1.8.4.12 ko:K07305,ko:K12267 ko00000,ko01000 Bacteria 47PPC@768503,4NQEY@976,COG0229@1,COG0229@2 NA|NA|NA O Conserved domain frequently associated with peptide methionine sulfoxide reductase MAG.T22.3_03543 1239962.C943_02019 3.9e-234 817.4 Cytophagia 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 47MET@768503,4NI42@976,COG2303@1,COG2303@2 NA|NA|NA E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate MAG.T22.3_03544 1094466.KQS_04565 8.5e-41 173.3 Flavobacterium Bacteria 1IJ3V@117743,2P0IR@237,4NPTQ@976,COG0614@1,COG0614@2 NA|NA|NA P PD-(D/E)XK nuclease superfamily MAG.T22.3_03545 1239962.C943_02020 0.0 1105.1 Cytophagia fadD 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 47K1E@768503,4NFPF@976,COG0318@1,COG0318@2 NA|NA|NA IQ Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II MAG.T22.3_03546 1239962.C943_02021 7.5e-219 766.1 Cytophagia acd 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 Bacteria 47NH5@768503,4NFD4@976,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA dehydrogenase, middle domain MAG.T22.3_03547 1239962.C943_02022 2.4e-262 911.0 Cytophagia 3.1.6.1,3.1.6.8 ko:K01130,ko:K01134 ko00140,ko00600,ko04142,map00140,map00600,map04142 R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 Bacteria 47JKY@768503,4NFRB@976,COG3119@1,COG3119@2 NA|NA|NA P C-terminal region of aryl-sulfatase MAG.T22.3_03548 1239962.C943_02023 3.3e-71 274.2 Cytophagia Bacteria 47QGD@768503,4NQEI@976,COG2318@1,COG2318@2 NA|NA|NA S Protein of unknown function (DUF1572) MAG.T22.3_03549 1239962.C943_02024 8.7e-201 706.1 Cytophagia pfkA 2.7.1.11,2.7.1.90 ko:K00850,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 iJN678.pfkA Bacteria 47TRF@768503,4NGN7@976,COG0205@1,COG0205@2 NA|NA|NA F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis MAG.T22.3_03550 886379.AEWI01000145_gene3280 1.2e-49 202.6 Bacteroidia vapC ko:K18828 ko00000,ko01000,ko02048,ko03016 Bacteria 2FU0G@200643,4NSBY@976,COG1487@1,COG1487@2 NA|NA|NA S PIN domain MAG.T22.3_03552 1239962.C943_02025 2.7e-160 571.2 Cytophagia dhaA GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.8.1.5 ko:K01563,ko:K22318 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 R05284,R05367,R05368,R05369,R05370,R07669,R07670 RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000 Bacteria 47P83@768503,4NFBJ@976,COG0596@1,COG0596@2 NA|NA|NA S Alpha/beta hydrolase family MAG.T22.3_03553 1239962.C943_02026 1.5e-100 372.1 Cytophagia Bacteria 47UYU@768503,4NN09@976,COG0664@1,COG0664@2 NA|NA|NA T PFAM Cyclic nucleotide-binding MAG.T22.3_03554 1317122.ATO12_00350 4.6e-74 284.6 Aquimarina Bacteria 1I8W7@117743,29552@1,2YJWT@290174,2ZSHM@2,4P8QW@976 NA|NA|NA MAG.T22.3_03556 1239962.C943_02027 1.7e-82 312.0 Bacteroidetes Bacteria 4NHRA@976,COG1680@1,COG1680@2 NA|NA|NA V beta-lactamase MAG.T22.3_03557 1239962.C943_02031 2.2e-31 141.7 Bacteroidetes Bacteria 2ED24@1,336Z2@2,4P3G3@976 NA|NA|NA MAG.T22.3_03558 1121011.AUCB01000003_gene2500 2.9e-35 154.8 Arenibacter Bacteria 1IFNR@117743,23IDU@178469,2BHTF@1,32BX3@2,4NRJU@976 NA|NA|NA MAG.T22.3_03559 1239962.C943_02032 8.8e-194 682.9 Cytophagia mntH Bacteria 47MUM@768503,4NENE@976,COG1914@1,COG1914@2 NA|NA|NA P PFAM natural resistance-associated macrophage protein MAG.T22.3_03560 1239962.C943_02033 5.6e-200 703.4 Cytophagia Bacteria 2C57D@1,2Z7RS@2,47KGH@768503,4NEKN@976 NA|NA|NA S Protein of unknown function (DUF2891) MAG.T22.3_03561 1239962.C943_00201 2.6e-230 804.3 Cytophagia aroA GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 Bacteria 47K1U@768503,4NE8T@976,COG0128@1,COG0128@2 NA|NA|NA E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate MAG.T22.3_03562 1239962.C943_00202 1.9e-173 615.1 Cytophagia aroB 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 47JBE@768503,4NGSS@976,COG0337@1,COG0337@2 NA|NA|NA E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) MAG.T22.3_03563 1239962.C943_00204 2.9e-212 744.2 Cytophagia aroF 2.5.1.54,5.4.99.5 ko:K03856,ko:K04092,ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022,M00024,M00025 R01715,R01826 RC00435,RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria 47K32@768503,4NDU4@976,COG1605@1,COG1605@2,COG2876@1,COG2876@2 NA|NA|NA E chorismate mutase MAG.T22.3_03564 1239962.C943_00206 5.6e-200 703.4 Cytophagia pheB 2.5.1.54,5.4.99.5 ko:K03856,ko:K04092,ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022,M00024,M00025 R01715,R01826 RC00435,RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria 47K32@768503,4NDU4@976,COG1605@1,COG1605@2,COG2876@1,COG2876@2 NA|NA|NA E chorismate mutase MAG.T22.3_03565 1239962.C943_00207 4.1e-220 770.4 Cytophagia putA ko:K00318,ko:K18318 ko00330,ko00332,ko01100,ko01110,ko01130,ko02024,map00330,map00332,map01100,map01110,map01130,map02024 R10507 RC00083 ko00000,ko00001,ko01000 Bacteria 47KMP@768503,4NEH5@976,COG0506@1,COG0506@2 NA|NA|NA E PFAM Proline dehydrogenase MAG.T22.3_03566 1239962.C943_00208 0.0 1130.2 Cytophagia lysS 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 47M2W@768503,4NDZN@976,COG1190@1,COG1190@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family MAG.T22.3_03567 1239962.C943_00209 4.2e-203 713.8 Cytophagia moeB 2.7.7.80,2.8.1.11 ko:K21029,ko:K21147 ko04122,map04122 R07459,R07461 RC00043 ko00000,ko00001,ko01000 Bacteria 47KG8@768503,4NFUD@976,COG0476@1,COG0476@2 NA|NA|NA H MoeZ MoeB domain MAG.T22.3_03568 1239962.C943_00210 4.7e-76 290.4 Cytophagia moaE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09395 RC02507 ko00000,ko00001,ko01000 Bacteria 47QKM@768503,4NP1X@976,COG0314@1,COG0314@2 NA|NA|NA H MoaE protein MAG.T22.3_03569 1239962.C943_00211 1.3e-160 572.4 Cytophagia moaC 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 R11372 RC03425 ko00000,ko00001,ko01000 Bacteria 47M7C@768503,4NHA0@976,COG0315@1,COG0315@2,COG0521@1,COG0521@2 NA|NA|NA H Molybdenum cofactor biosynthesis protein MAG.T22.3_03570 1239962.C943_00212 6.6e-44 183.0 Cytophagia Bacteria 2EK9D@1,33DZP@2,47T67@768503,4NXY8@976 NA|NA|NA MAG.T22.3_03571 1239962.C943_00213 2.2e-128 464.9 Cytophagia rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 ko00000,ko01000,ko03009 Bacteria 47PRE@768503,4NE2S@976,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit MAG.T22.3_03572 1239962.C943_00215 9.7e-230 802.4 Cytophagia Bacteria 47JWN@768503,4NH6C@976,COG2819@1,COG2819@2 NA|NA|NA S esterase MAG.T22.3_03573 1239962.C943_00216 4.9e-260 903.3 Cytophagia pepA 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 47KV8@768503,4NDWT@976,COG0260@1,COG0260@2 NA|NA|NA E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides MAG.T22.3_03574 1239962.C943_00217 6e-235 819.7 Cytophagia hsvB 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 47MVS@768503,4NGM6@976,COG1181@1,COG1181@2 NA|NA|NA M ATP-grasp domain MAG.T22.3_03575 1239962.C943_00218 4.7e-212 743.8 Cytophagia Bacteria 47YDT@768503,4PKUG@976,COG1216@1,COG1216@2 NA|NA|NA S Glycosyl transferase, family 2 MAG.T22.3_03576 1239962.C943_00219 6.1e-223 780.0 Cytophagia Bacteria 47N5W@768503,4NER4@976,COG2148@1,COG2148@2 NA|NA|NA M sugar transferase MAG.T22.3_03577 1239962.C943_00222 4.6e-216 756.9 Bacteroidetes 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 4NMVY@976,COG3919@1,COG3919@2 NA|NA|NA S ATP-grasp domain MAG.T22.3_03579 1239962.C943_00223 5.9e-216 756.5 Bacteroidetes 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 4NMVY@976,COG3919@1,COG3919@2 NA|NA|NA S ATP-grasp domain MAG.T22.3_03580 1239962.C943_00224 2.5e-125 454.9 Cytophagia Bacteria 2DDZV@1,32Q7H@2,47W4X@768503,4PBPP@976 NA|NA|NA MAG.T22.3_03581 1250006.JHZZ01000001_gene342 1.2e-07 62.0 Flavobacteriia Bacteria 1I55X@117743,2DNTT@1,32Z3E@2,4NVJI@976 NA|NA|NA MAG.T22.3_03582 1239962.C943_00229 9.6e-74 282.7 Cytophagia Bacteria 2DMPB@1,32SV8@2,47SFC@768503,4NSG4@976 NA|NA|NA MAG.T22.3_03583 1239962.C943_00230 2.5e-122 444.9 Cytophagia Bacteria 2C9V5@1,2Z8F9@2,47S8V@768503,4NG2N@976 NA|NA|NA MAG.T22.3_03586 641524.ADICYQ_5360 1.3e-188 665.6 Cytophagia hsdM 2.1.1.72 ko:K03427,ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko02048,ko03400 Bacteria 47JT0@768503,4NG0E@976,COG0286@1,COG0286@2,COG2852@1,COG2852@2 NA|NA|NA V HsdM N-terminal domain MAG.T22.3_03587 1392488.JHZY01000004_gene1788 3.4e-41 175.3 Flavobacteriia Bacteria 1IJ4I@117743,4NYEI@976,COG0393@1,COG0393@2 NA|NA|NA S Putative heavy-metal-binding MAG.T22.3_03589 1239962.C943_04250 7.1e-75 286.6 Bacteroidetes Bacteria 2ADAU@1,31308@2,4NRKI@976 NA|NA|NA MAG.T22.3_03590 1239962.C943_04252 4e-181 640.6 Bacteroidetes Bacteria 2C79J@1,2ZIGY@2,4P936@976 NA|NA|NA MAG.T22.3_03591 1239962.C943_04253 2.1e-108 398.3 Bacteroidetes Bacteria 2CCS0@1,331YJ@2,4NVDH@976 NA|NA|NA MAG.T22.3_03592 1239962.C943_04255 4.9e-201 706.8 Cytophagia ko:K03641 ko00000,ko02000 2.C.1.2 Bacteria 47NM2@768503,4NM2C@976,COG0823@1,COG0823@2 NA|NA|NA U Involved in the tonB-independent uptake of proteins MAG.T22.3_03593 1239962.C943_04256 8.6e-204 716.1 Cytophagia 1.14.19.3 ko:K00508 ko00591,ko01100,map00591,map01100 R07063 RC00917 ko00000,ko00001,ko01000,ko01004 Bacteria 47JP1@768503,4NERD@976,COG3239@1,COG3239@2 NA|NA|NA I fatty acid desaturase MAG.T22.3_03594 1239962.C943_04258 0.0 1352.4 Cytophagia 3.5.1.11,3.5.1.97 ko:K01434,ko:K07116 ko00311,ko01130,map00311,map01130 R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 Bacteria 47K4Y@768503,4NGXQ@976,COG2366@1,COG2366@2 NA|NA|NA S Penicillin amidase MAG.T22.3_03595 1239962.C943_04259 8.2e-137 493.0 Bacteroidetes yjjP Bacteria 4NIU3@976,COG2966@1,COG2966@2 NA|NA|NA S COGs COG2966 conserved MAG.T22.3_03596 1239962.C943_04260 3.1e-76 291.2 Bacteroidetes Bacteria 4NP5R@976,COG3610@1,COG3610@2 NA|NA|NA S Psort location CytoplasmicMembrane, score 10.00 MAG.T22.3_03598 1239962.C943_04261 7.7e-120 436.4 Cytophagia Bacteria 2C7HJ@1,31BFZ@2,47WSM@768503,4NRGQ@976 NA|NA|NA S Outer membrane protein beta-barrel domain MAG.T22.3_03599 1239962.C943_04267 1.2e-109 402.9 Bacteroidetes Bacteria 4NW8Z@976,COG3548@1,COG3548@2 NA|NA|NA S Protein of unknown function (DUF1211) MAG.T22.3_03600 1239962.C943_04268 1.8e-62 245.4 Bacteroidetes Bacteria 4NMS3@976,COG5395@1,COG5395@2 NA|NA|NA S membrane protein (DUF2306) MAG.T22.3_03601 1239962.C943_04269 2.8e-171 607.8 Bacteroidetes pip 3.4.11.5,3.5.1.101 ko:K01259,ko:K18457 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 4PNPN@976,COG0596@1,COG0596@2 NA|NA|NA S Alpha/beta hydrolase family MAG.T22.3_03602 1239962.C943_04271 5.1e-128 463.8 Bacteroidetes Bacteria 4NRZT@976,COG0526@1,COG0526@2 NA|NA|NA CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MAG.T22.3_03603 1239962.C943_04272 3.3e-109 401.0 Cytophagia cccE Bacteria 47QS4@768503,4NQXA@976,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T22.3_03604 1229487.AMYW01000002_gene1491 5.1e-21 108.2 Flavobacterium Bacteria 1I1TH@117743,28PKG@1,2NZUF@237,2ZC9Y@2,4NNB0@976 NA|NA|NA MAG.T22.3_03605 1239962.C943_04274 6.8e-72 276.6 Cytophagia Bacteria 2DMYZ@1,32UGH@2,47R9K@768503,4NTDD@976 NA|NA|NA S Domain of unknown function (DUF4345) MAG.T22.3_03606 1239962.C943_04275 1e-90 339.3 Cytophagia 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 Bacteria 47PT4@768503,4NQK0@976,COG0262@1,COG0262@2 NA|NA|NA H PFAM RibD C-terminal domain MAG.T22.3_03608 1239962.C943_04277 6.1e-143 513.5 Bacteroidetes Bacteria 4NGQY@976,COG1028@1,COG1028@2 NA|NA|NA IQ Short-chain dehydrogenase reductase sdr MAG.T22.3_03609 1239962.C943_04278 2.1e-199 701.4 Cytophagia 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 47PTG@768503,4NFEN@976,COG0793@1,COG0793@2 NA|NA|NA M PFAM Peptidase family S41 MAG.T22.3_03611 1239962.C943_04280 6.5e-265 919.5 Cytophagia 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 47PB5@768503,4NGGJ@976,COG0793@1,COG0793@2 NA|NA|NA M PFAM Peptidase family S41 MAG.T22.3_03612 1239962.C943_04281 0.0 1929.1 Cytophagia Bacteria 47NEM@768503,4NHSC@976,COG3292@1,COG3292@2,COG4585@1,COG4585@2 NA|NA|NA T Two component regulator three Y MAG.T22.3_03613 1239962.C943_04282 8.8e-113 412.9 Cytophagia Bacteria 47PWE@768503,4NHTM@976,COG2197@1,COG2197@2 NA|NA|NA KT Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain MAG.T22.3_03614 1239962.C943_04283 1.3e-97 362.5 Cytophagia ko:K03088 ko00000,ko03021 Bacteria 47PTY@768503,4NQCH@976,COG1595@1,COG1595@2 NA|NA|NA K TIGRFAM RNA polymerase sigma factor, sigma-70 family MAG.T22.3_03615 1239962.C943_04288 0.0 1438.7 Cytophagia 3.2.1.78 ko:K01218 ko00051,ko02024,map00051,map02024 R01332 RC00467 ko00000,ko00001,ko01000 GH26 Bacteria 47Y8X@768503,4PN3M@976,COG3291@1,COG3291@2 NA|NA|NA S Repeats in polycystic kidney disease 1 (PKD1) and other proteins MAG.T22.3_03616 1239962.C943_04289 2.1e-134 485.0 Cytophagia Bacteria 47VIJ@768503,4NQAP@976,COG4122@1,COG4122@2 NA|NA|NA S Methyltransferase domain MAG.T22.3_03617 1239962.C943_04290 1.5e-172 612.1 Cytophagia Bacteria 47P2Y@768503,4PKKH@976,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold MAG.T22.3_03618 1239962.C943_04294 4.3e-161 573.9 Cytophagia GO:0003674,GO:0003824,GO:0016787 Bacteria 47U8C@768503,4NM26@976,COG0596@1,COG0596@2 NA|NA|NA S Hydrolase or acyltransferase (Alpha beta hydrolase superfamily)-like protein MAG.T22.3_03619 1239962.C943_04297 7.5e-245 852.8 Cytophagia Bacteria 47MBJ@768503,4NH51@976,COG2972@1,COG2972@2 NA|NA|NA T regulator of cell autolysis MAG.T22.3_03620 1239962.C943_04298 8.2e-117 426.4 Cytophagia Bacteria 47JDI@768503,4NF8S@976,COG3279@1,COG3279@2 NA|NA|NA K Response regulator of the LytR AlgR family MAG.T22.3_03621 1239962.C943_02782 3.4e-143 514.2 Cytophagia 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria 47KFU@768503,4NGMS@976,COG2133@1,COG2133@2 NA|NA|NA G Domain of Unknown Function (DUF1080) MAG.T22.3_03622 1089547.KB913013_gene2958 2.8e-59 235.0 Cytophagia Bacteria 47P73@768503,4NMZH@976,COG1917@1,COG1917@2 NA|NA|NA S Cupin domain MAG.T22.3_03623 1239962.C943_02784 1.1e-286 992.3 Cytophagia Bacteria 47YN7@768503,4NPRK@976,COG3210@1,COG3210@2 NA|NA|NA U Pkd domain containing protein MAG.T22.3_03626 1239962.C943_03249 0.0 1635.5 Cytophagia Bacteria 47KV2@768503,4NHM6@976,COG4288@1,COG4288@2 NA|NA|NA M Lamin Tail Domain MAG.T22.3_03628 1239962.C943_03251 4e-60 237.3 Cytophagia dksA ko:K06204 ko02026,map02026 ko00000,ko00001,ko03000,ko03009,ko03021 Bacteria 47Q8I@768503,4NNID@976,COG1734@1,COG1734@2 NA|NA|NA T PFAM Prokaryotic dksA traR C4-type zinc finger MAG.T22.3_03629 1189612.A33Q_1544 7.1e-82 310.1 Cytophagia scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K06024 ko00000,ko03036 Bacteria 47NG4@768503,4NPG3@976,COG1386@1,COG1386@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves MAG.T22.3_03630 1189612.A33Q_1545 1.6e-74 285.8 Cytophagia sprT ko:K02742 ko00000 Bacteria 47QAA@768503,4NDXX@976,COG3091@1,COG3091@2 NA|NA|NA S PFAM SprT-like family MAG.T22.3_03632 1239962.C943_03254 1.8e-245 854.7 Cytophagia der GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 ko:K03977 ko00000,ko03009 Bacteria 47K6M@768503,4NE2J@976,COG1160@1,COG1160@2 NA|NA|NA S GTPase that plays an essential role in the late steps of ribosome biogenesis MAG.T22.3_03633 1239962.C943_03255 1.4e-161 575.5 Cytophagia era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 ko:K03595,ko:K06883 ko00000,ko03009,ko03029 Bacteria 47K35@768503,4NES2@976,COG1159@1,COG1159@2 NA|NA|NA S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism MAG.T22.3_03635 1239962.C943_03256 2.7e-166 591.3 Cytophagia tdcB 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 Bacteria 47UGD@768503,4P1Y7@976,COG1171@1,COG1171@2 NA|NA|NA E Pyridoxal-phosphate dependent enzyme MAG.T22.3_03636 1239962.C943_03258 1.2e-94 352.8 Cytophagia Bacteria 47PNX@768503,4NN4Q@976,COG0739@1,COG0739@2 NA|NA|NA M PFAM Peptidase family M23 MAG.T22.3_03637 1239962.C943_03259 2.2e-126 458.4 Cytophagia coaX 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 47K5B@768503,4NE9E@976,COG1521@1,COG1521@2 NA|NA|NA H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis MAG.T22.3_03638 1239962.C943_03260 2.6e-85 321.2 Cytophagia Bacteria 47PUS@768503,4NNJS@976,COG0454@1,COG0456@2 NA|NA|NA K PFAM Acetyltransferase (GNAT) family MAG.T22.3_03639 1239962.C943_03261 1.1e-128 466.1 Cytophagia Bacteria 47P21@768503,4NMH8@976,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase MAG.T22.3_03640 1239962.C943_03262 4.4e-88 330.5 Cytophagia ogt GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 ko:K00567 ko00000,ko01000,ko03400 Bacteria 47PW6@768503,4NFYC@976,COG0350@1,COG0350@2 NA|NA|NA L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated MAG.T22.3_03642 1189612.A33Q_0084 8.2e-130 470.3 Cytophagia ko:K04763 ko00000,ko03036 Bacteria 47KKB@768503,4NGE1@976,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family MAG.T22.3_03644 1239962.C943_00109 3e-165 587.8 Cytophagia Bacteria 47N8X@768503,4NG8Y@976,COG0451@1,COG0451@2 NA|NA|NA GM NAD dependent epimerase/dehydratase family MAG.T22.3_03645 1239962.C943_00108 3.1e-140 504.6 Cytophagia ko:K09973 ko00000 Bacteria 47PD6@768503,4NN4U@976,COG3735@1,COG3735@2 NA|NA|NA S TraB family MAG.T22.3_03646 1239962.C943_00107 0.0 1132.5 Cytophagia yhcR 3.1.3.5,3.6.1.45 ko:K01081,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 iE2348C_1286.E2348C_4246,iECS88_1305.ECS88_4396,iLF82_1304.LF82_624 Bacteria 47NV1@768503,4NESM@976,COG0737@1,COG0737@2 NA|NA|NA F 5'-nucleotidase, C-terminal domain MAG.T22.3_03647 1239962.C943_00106 1.1e-227 795.8 Cytophagia rhlE 3.6.4.13 ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 47J9E@768503,4NEVI@976,COG0513@1,COG0513@2 NA|NA|NA L Belongs to the DEAD box helicase family MAG.T22.3_03648 1492738.FEM21_22010 2e-37 162.2 Flavobacterium ko:K21498 ko00000,ko02048 Bacteria 1I2Q9@117743,2NX16@237,4NMVH@976,COG3093@1,COG3093@2 NA|NA|NA K Plasmid maintenance system antidote protein MAG.T22.3_03649 1189612.A33Q_0624 1.3e-71 276.2 Cytophagia Bacteria 47X5J@768503,4NKE9@976,COG2253@1,COG2253@2 NA|NA|NA S Nucleotidyl transferase AbiEii toxin, Type IV TA system MAG.T22.3_03650 1239962.C943_00105 1.2e-100 372.5 Cytophagia Bacteria 47PYW@768503,4NMSF@976,COG0662@1,COG0662@2 NA|NA|NA G Protein of unknown function (DUF861) MAG.T22.3_03651 1239962.C943_00103 9.7e-99 366.7 Cytophagia Bacteria 47P27@768503,4NJUT@976,COG2207@1,COG2207@2 NA|NA|NA K Helix-turn-helix domain MAG.T22.3_03652 1239962.C943_00102 7.5e-77 293.1 Cytophagia Bacteria 47YNP@768503,4PMQ6@976,COG2002@1,COG2002@2 NA|NA|NA K Domain of unknown function (DUF1905) MAG.T22.3_03653 1239962.C943_00100 4.4e-160 570.5 Cytophagia ygiD GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046566,GO:0051213,GO:0055114 1.13.11.8 ko:K04100,ko:K15777 ko00362,ko00624,ko00627,ko00965,ko01120,map00362,map00624,map00627,map00965,map01120 R01632,R03550,R04280,R08836,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 Bacteria 47KW5@768503,4NFGT@976,COG3384@1,COG3384@2 NA|NA|NA S PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase MAG.T22.3_03654 1239962.C943_00099 1.1e-107 396.0 Bacteroidetes yjl217W ko:K09702 ko00000 Bacteria 4NKFW@976,COG3506@1,COG3506@2 NA|NA|NA S Protein of unknown function (DUF1349) MAG.T22.3_03656 643867.Ftrac_0068 1.7e-179 636.3 Cytophagia ko:K11159 ko00000 Bacteria 47N3V@768503,4NJEV@976,COG3670@1,COG3670@2 NA|NA|NA Q Retinal pigment epithelial membrane protein MAG.T22.3_03657 1239962.C943_02799 1.4e-64 253.8 Cytophagia Bacteria 47MR3@768503,4NEVN@976,COG2114@1,COG2114@2,COG3292@1,COG3292@2 NA|NA|NA T Belongs to the adenylyl cyclase class-4 guanylyl cyclase family MAG.T22.3_03658 1239962.C943_00095 1.3e-191 675.6 Cytophagia Bacteria 47NWH@768503,4NI1Z@976,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T22.3_03659 1239962.C943_00094 0.0 1347.4 Cytophagia yuxL 3.4.19.1 ko:K01303 ko00000,ko01000,ko01002 Bacteria 47MWY@768503,4NHS5@976,COG0823@1,COG0823@2,COG1506@1,COG1506@2 NA|NA|NA EU Peptidase S9 prolyl oligopeptidase active site domain protein MAG.T22.3_03660 1239962.C943_00092 1e-148 532.7 Bacteroidetes rnfB ko:K03616 ko00000 Bacteria 4NFEB@976,COG2878@1,COG2878@2 NA|NA|NA C electron transport complex, RnfABCDGE type, B subunit MAG.T22.3_03661 1239962.C943_00091 5.9e-160 570.1 Bacteria petH GO:0005575,GO:0005622,GO:0005623,GO:0009579,GO:0016020,GO:0034357,GO:0042651,GO:0044424,GO:0044436,GO:0044464 1.14.13.208,1.18.1.2,1.19.1.1 ko:K00528,ko:K02287,ko:K02641,ko:K15511 ko00195,ko00196,ko00362,ko01100,map00195,map00196,map00362,map01100 R09555,R10159 RC01739 ko00000,ko00001,ko00194,ko01000 iJN678.petH Bacteria COG0369@1,COG0369@2 NA|NA|NA C hydroxylamine reductase activity MAG.T22.3_03662 1239962.C943_00089 4.6e-92 344.0 Cytophagia rnfA ko:K03617 ko00000 Bacteria 47XMF@768503,4NGEZ@976,COG4657@1,COG4657@2 NA|NA|NA U Part of a membrane complex involved in electron transport MAG.T22.3_03663 1239962.C943_00088 1.9e-107 395.2 Bacteroidetes rnfE GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944 2.3.1.243,4.2.99.18 ko:K02560,ko:K03613,ko:K10773 ko00540,ko01100,ko03410,map00540,map01100,map03410 M00060 R05075 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005,ko03400 Bacteria 4NHHP@976,COG4660@1,COG4660@2 NA|NA|NA C Part of a membrane complex involved in electron transport MAG.T22.3_03664 1239962.C943_00087 5.4e-119 433.7 Bacteria ko:K03612 ko00000 Bacteria COG4659@1,COG4659@2 NA|NA|NA C FMN binding MAG.T22.3_03665 1239962.C943_00086 4.3e-178 630.6 Cytophagia rnfD 1.6.5.8 ko:K00347,ko:K03614 ko00000,ko01000 Bacteria 47XQE@768503,4NESE@976,COG4658@1,COG4658@2 NA|NA|NA U Part of a membrane complex involved in electron transport MAG.T22.3_03666 1239962.C943_00085 1.4e-243 848.6 Bacteroidetes ko:K03615 ko00000 Bacteria 4NIS7@976,COG4656@1,COG4656@2 NA|NA|NA C Part of a membrane complex involved in electron transport MAG.T22.3_03667 1239962.C943_00084 0.0 3288.8 Bacteroidetes nifJ 1.2.7.1 ko:K03737,ko:K05337 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 4NF4F@976,COG0674@1,COG0674@2,COG1013@1,COG1013@2,COG1014@1,COG1014@2,COG1141@1,COG1141@2,COG1145@1,COG1145@2,COG1146@1,COG1146@2 NA|NA|NA C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin MAG.T22.3_03668 1239962.C943_00083 1.6e-58 231.9 Bacteroidetes Bacteria 2EDMN@1,337HG@2,4NWVI@976 NA|NA|NA S HEPN domain MAG.T22.3_03669 1239962.C943_00082 0.0 1464.5 Cytophagia 2.7.13.3 ko:K02482 ko00000,ko01000,ko01001,ko02022 Bacteria 47UPB@768503,4PI91@976,COG2203@1,COG2203@2,COG4191@1,COG4191@2 NA|NA|NA T GAF domain MAG.T22.3_03670 1239962.C943_00081 3.1e-117 427.9 Cytophagia ko:K07705 ko02020,map02020 M00492 ko00000,ko00001,ko00002,ko02022 Bacteria 47PKK@768503,4NKXC@976,COG3279@1,COG3279@2 NA|NA|NA T Two component transcriptional regulator, LytTR family MAG.T22.3_03672 1239962.C943_00079 3.6e-106 391.0 Bacteroidetes Bacteria 4NSVW@976,COG5395@1,COG5395@2 NA|NA|NA S Predicted membrane protein (DUF2306) MAG.T22.3_03673 1239962.C943_00078 1.3e-187 662.1 Cytophagia Bacteria 47TXQ@768503,4NMGT@976,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T22.3_03674 1239962.C943_00076 2.4e-198 698.0 Cytophagia Bacteria 47KPK@768503,4NFAF@976,COG3503@1,COG3503@2 NA|NA|NA S Protein of unknown function (DUF1624) MAG.T22.3_03675 1239962.C943_00075 1e-211 742.7 Cytophagia amaB 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 47N41@768503,4NJEK@976,COG0624@1,COG0624@2 NA|NA|NA E Peptidase family M20/M25/M40 MAG.T22.3_03676 383372.Rcas_0538 9e-18 95.9 Bacteria Bacteria COG2442@1,COG2442@2 NA|NA|NA K InterPro IPR007367 MAG.T22.3_03677 317619.ANKN01000034_gene2506 7e-27 126.7 Cyanobacteria Bacteria 1G8JH@1117,COG4634@1,COG4634@2 NA|NA|NA S Mut7-C RNAse domain MAG.T22.3_03678 1239962.C943_00074 4.1e-123 447.6 Cytophagia Bacteria 47JFN@768503,4NES7@976,COG3000@1,COG3000@2 NA|NA|NA I Fatty acid hydroxylase superfamily MAG.T22.3_03679 1239962.C943_00073 3.6e-309 1067.0 Cytophagia pdtaS 2.7.13.3 ko:K00936 M00839 ko00000,ko00002,ko01000,ko01001,ko02022 Bacteria 47MHJ@768503,4NINT@976,COG3920@1,COG3920@2 NA|NA|NA T Histidine kinase MAG.T22.3_03680 1239962.C943_00072 1.7e-114 418.7 Cytophagia Bacteria 47RA5@768503,4NGXE@976,COG2318@1,COG2318@2 NA|NA|NA S Protein of unknown function (DUF664) MAG.T22.3_03681 1120965.AUBV01000006_gene2226 4.2e-74 284.6 Bacteroidetes VV2631 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 4NRNA@976,COG3703@1,COG3703@2 NA|NA|NA P Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides MAG.T22.3_03682 1239962.C943_00070 1e-216 759.2 Cytophagia dmpA 3.4.11.19 ko:K01266 ko00000,ko01000,ko01002 Bacteria 47KDB@768503,4NGDT@976,COG3191@1,COG3191@2 NA|NA|NA EQ Peptidase family S58 MAG.T22.3_03683 1239962.C943_00069 5.8e-73 280.4 Bacteroidetes Bacteria 2CG01@1,33W86@2,4P395@976 NA|NA|NA MAG.T22.3_03684 1239962.C943_00067 2.6e-112 411.4 Bacteroidetes ko:K07275 ko00000 Bacteria 4NMFE@976,COG3047@1,COG3047@2 NA|NA|NA MAG.T22.3_03685 1120966.AUBU01000013_gene433 1.3e-15 90.1 Bacteroidetes Bacteria 28N4A@1,2ZB9T@2,4NS50@976 NA|NA|NA S Domain of unknown function (DUF4136) MAG.T22.3_03686 1239962.C943_00064 3.1e-70 271.2 Cytophagia Bacteria 47WZP@768503,4NUN7@976,COG4319@1,COG4319@2 NA|NA|NA S Domain of unknown function (DUF4440) MAG.T22.3_03687 1239962.C943_00063 3.8e-120 437.6 Bacteroidetes Bacteria 2E3AK@1,32QZA@2,4NS4M@976 NA|NA|NA MAG.T22.3_03688 1239962.C943_00062 3.2e-84 317.8 Cytophagia Bacteria 2DM4C@1,31P4J@2,47USM@768503,4NQ7K@976 NA|NA|NA MAG.T22.3_03690 1239962.C943_00060 7.6e-59 233.0 Cytophagia Bacteria 47QFA@768503,4NQ69@976,COG0745@1,COG0745@2 NA|NA|NA T response regulator, receiver MAG.T22.3_03691 1239962.C943_00059 0.0 2436.4 Cytophagia Bacteria 47N98@768503,4NEJX@976,COG3292@1,COG3292@2,COG4191@1,COG4191@2 NA|NA|NA T Y_Y_Y domain MAG.T22.3_03692 1239962.C943_00058 2.3e-60 238.0 Cytophagia Bacteria 47QFA@768503,4NQ69@976,COG0745@1,COG0745@2 NA|NA|NA T response regulator, receiver MAG.T22.3_03693 1239962.C943_00057 3.3e-208 731.9 Cytophagia Bacteria 47U6P@768503,4NEJX@976,COG4191@1,COG4191@2 NA|NA|NA T SnoaL-like domain MAG.T22.3_03694 1239962.C943_03618 1.5e-250 871.7 Cytophagia surA 5.2.1.8 ko:K03771 ko00000,ko01000,ko03110 Bacteria 47JPW@768503,4NEW0@976,COG0760@1,COG0760@2 NA|NA|NA O peptidyl-prolyl isomerase MAG.T22.3_03695 1239962.C943_03617 1.1e-110 406.4 Cytophagia epsD 5.2.1.8 ko:K03771 ko00000,ko01000,ko03110 Bacteria 47NE3@768503,4NG2P@976,COG0760@1,COG0760@2 NA|NA|NA O Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation MAG.T22.3_03696 1239962.C943_03616 0.0 1245.3 Cytophagia 5.2.1.8 ko:K03769,ko:K03771 ko00000,ko01000,ko03110 Bacteria 47K78@768503,4NGIR@976,COG0760@1,COG0760@2 NA|NA|NA O peptidyl-prolyl isomerase MAG.T22.3_03697 1239962.C943_03615 4e-66 257.3 Cytophagia rsbW 2.7.11.1,3.1.3.3 ko:K04757,ko:K07315 ko00000,ko01000,ko01001,ko03021 Bacteria 47RU2@768503,4NV3J@976,COG2172@1,COG2172@2 NA|NA|NA T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MAG.T22.3_03698 1239962.C943_03614 7e-53 213.0 Cytophagia ko:K04749,ko:K06378 ko00000,ko03021 Bacteria 47WUM@768503,4PC5I@976,COG1366@1,COG1366@2 NA|NA|NA T STAS domain MAG.T22.3_03699 1239962.C943_03613 0.0 1305.8 Cytophagia rsbU 3.1.3.3 ko:K07315 ko00000,ko01000,ko03021 Bacteria 47JNJ@768503,4NJMJ@976,COG2208@1,COG2208@2 NA|NA|NA KT PFAM Stage II sporulation protein E (SpoIIE) MAG.T22.3_03700 1239962.C943_03612 7.2e-119 433.3 Cytophagia Bacteria 2C8XG@1,2Z7PK@2,47P85@768503,4NEU8@976 NA|NA|NA S Protein of unknown function (DUF4197) MAG.T22.3_03701 1239962.C943_03611 1.6e-46 191.8 Cytophagia Bacteria 47S8C@768503,4NXIK@976,COG5512@1,COG5512@2 NA|NA|NA S Protein of unknown function (DUF721) MAG.T22.3_03702 1239962.C943_03610 1e-154 552.7 Cytophagia hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 iNJ661.Rv2388c Bacteria 47JXR@768503,4NFEE@976,COG0635@1,COG0635@2 NA|NA|NA H Involved in the biosynthesis of porphyrin-containing compound MAG.T22.3_03703 1239962.C943_03609 1.2e-299 1035.0 Cytophagia ko:K07277 ko00000,ko02000,ko03029 1.B.33 Bacteria 47NVM@768503,4NF35@976,COG4775@1,COG4775@2 NA|NA|NA M Outer membrane protein protective antigen OMA87 MAG.T22.3_03704 153721.MYP_932 1.4e-07 64.3 Cytophagia Bacteria 28JHR@1,2Z9B8@2,47K46@768503,4NK3E@976 NA|NA|NA S Domain of unknown function (DUF4271) MAG.T22.3_03705 1239962.C943_03607 1.5e-138 498.8 Cytophagia hemD 2.1.1.107,2.5.1.61,4.2.1.75 ko:K01719,ko:K01749,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084,R03165,R03194 RC00003,RC00871,RC01861,RC02317 ko00000,ko00001,ko00002,ko01000 Bacteria 47JYP@768503,4NEQ3@976,COG1587@1,COG1587@2 NA|NA|NA H Uroporphyrinogen-III synthase MAG.T22.3_03706 1239962.C943_03606 2.5e-175 621.3 Cytophagia Bacteria 47PVA@768503,4NKND@976,COG0226@1,COG0226@2 NA|NA|NA P Type IX secretion system membrane protein PorP/SprF MAG.T22.3_03707 1239962.C943_03605 2.1e-183 648.3 Cytophagia gldK Bacteria 47KHB@768503,4NGY2@976,COG1262@1,COG1262@2 NA|NA|NA S TIGRFAM Gliding motility-associated lipoprotein GldK MAG.T22.3_03708 1239962.C943_03604 2.7e-110 404.8 Cytophagia gldL Bacteria 28IG3@1,2Z8HM@2,47MA3@768503,4NFJR@976 NA|NA|NA S TIGRFAM gliding motility-associated protein GldL MAG.T22.3_03709 1239962.C943_03603 7.9e-267 926.0 Cytophagia gldM Bacteria 28HG4@1,2Z7S0@2,47JTS@768503,4NE3G@976 NA|NA|NA S TIGRFAM Gliding motility-associated protein GldM MAG.T22.3_03710 1239962.C943_03602 5.9e-154 550.1 Cytophagia Bacteria 2C97B@1,2ZAEJ@2,47MC2@768503,4NEK0@976 NA|NA|NA S TIGRFAM gliding motility associated protien GldN MAG.T22.3_03711 1239962.C943_03601 0.0 1143.6 Cytophagia uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 47JXP@768503,4NE61@976,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision MAG.T22.3_03712 1239962.C943_03600 0.0 1535.0 Cytophagia mrcA 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 47K6R@768503,4NECJ@976,COG5009@1,COG5009@2 NA|NA|NA M Penicillin binding protein transpeptidase MAG.T22.3_03713 1239962.C943_03599 0.0 1602.8 Cytophagia ko:K02453 ko03070,ko05111,map03070,map05111 M00331 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 47Y51@768503,4PKGA@976,COG1729@1,COG1729@2 NA|NA|NA S Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division MAG.T22.3_03714 1239962.C943_03598 1.9e-158 565.1 Cytophagia nlpD_1 Bacteria 47PPP@768503,4NFZN@976,COG0739@1,COG0739@2 NA|NA|NA M PFAM Peptidase family M23 MAG.T22.3_03715 1239962.C943_03597 1.1e-28 132.9 Cytophagia Bacteria 47SCM@768503,4NUZA@976,COG1664@1,COG1664@2 NA|NA|NA M Integral membrane protein CcmA involved in cell shape determination MAG.T22.3_03716 1239962.C943_03595 1.5e-54 218.8 Cytophagia Bacteria 2EDVX@1,337R3@2,47SDY@768503,4NX14@976 NA|NA|NA MAG.T22.3_03717 1239962.C943_03594 1.3e-182 645.6 Cytophagia atpB ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 Bacteria 47JYV@768503,4NEPK@976,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane MAG.T22.3_03718 1189612.A33Q_4345 4e-24 117.1 Cytophagia atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iHN637.CLJU_RS01165 Bacteria 47S5V@768503,4NURW@976,COG0636@1,COG0636@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation MAG.T22.3_03719 1239962.C943_03592 8.8e-76 289.7 Cytophagia atpF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 e_coli_core.b3736,iAF1260.b3736,iB21_1397.B21_03564,iBWG_1329.BWG_3427,iE2348C_1286.E2348C_4046,iEC042_1314.EC042_4123,iEC55989_1330.EC55989_4211,iECABU_c1320.ECABU_c42210,iECBD_1354.ECBD_4296,iECB_1328.ECB_03620,iECDH10B_1368.ECDH10B_3923,iECDH1ME8569_1439.ECDH1ME8569_3624,iECD_1391.ECD_03620,iECED1_1282.ECED1_4426,iECH74115_1262.ECH74115_5172,iECIAI1_1343.ECIAI1_3920,iECIAI39_1322.ECIAI39_4340,iECO103_1326.ECO103_4422,iECO111_1330.ECO111_4570,iECO26_1355.ECO26_4842,iECOK1_1307.ECOK1_4185,iECP_1309.ECP_3935,iECS88_1305.ECS88_4158,iECSE_1348.ECSE_4026,iECSF_1327.ECSF_3584,iECSP_1301.ECSP_4786,iECUMN_1333.ECUMN_4266,iECW_1372.ECW_m4039,iECs_1301.ECs4678,iEKO11_1354.EKO11_4609,iETEC_1333.ETEC_4027,iEcDH1_1363.EcDH1_4231,iEcE24377_1341.EcE24377A_4252,iEcHS_1320.EcHS_A3952,iEcSMS35_1347.EcSMS35_4104,iEcolC_1368.EcolC_4258,iG2583_1286.G2583_4532,iJO1366.b3736,iJR904.b3736,iSDY_1059.SDY_4012,iSFV_1184.SFV_3762,iSF_1195.SF3816,iSFxv_1172.SFxv_4159,iSSON_1240.SSON_3883,iS_1188.S3952,iSbBS512_1146.SbBS512_E4185,iUMN146_1321.UM146_18870,iUMNK88_1353.UMNK88_4548,iUTI89_1310.UTI89_C4291,iWFL_1372.ECW_m4039,iY75_1357.Y75_RS18390,iZ_1308.Z5234,ic_1306.c4664 Bacteria 47Q9K@768503,4NQKA@976,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) MAG.T22.3_03720 1239962.C943_03591 5.6e-87 327.0 Cytophagia atpH GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iSF_1195.SF3815,iSFxv_1172.SFxv_4157,iS_1188.S3953 Bacteria 47QGS@768503,4NSNF@976,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation MAG.T22.3_03721 1239962.C943_03590 4.1e-292 1010.0 Cytophagia atpA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iSB619.SA_RS10975 Bacteria 47JFI@768503,4NFZW@976,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit MAG.T22.3_03722 1239962.C943_03589 4.9e-154 550.4 Cytophagia atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138 Bacteria 47JM0@768503,4NECM@976,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex MAG.T22.3_03723 1239962.C943_03588 0.0 1270.8 Cytophagia 3.1.1.17,5.3.3.19 ko:K01053,ko:K14274,ko:K19547 ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129,M00787 R01519,R02427,R02933,R03751 RC00537,RC00713,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47KMQ@768503,4NIMX@976,COG1917@1,COG1917@2,COG3386@1,COG3386@2 NA|NA|NA G PFAM SMP-30 Gluconolaconase MAG.T22.3_03724 1239962.C943_02850 7.9e-77 293.1 Cytophagia Bacteria 2F4IN@1,33X8B@2,47UZN@768503,4P3SW@976 NA|NA|NA MAG.T22.3_03725 1239962.C943_02849 2.5e-203 714.5 Cytophagia paaE ko:K02613 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 47KY6@768503,4NF24@976,COG1018@1,COG1018@2 NA|NA|NA C PFAM 2Fe-2S iron-sulfur cluster binding domain MAG.T22.3_03726 1239962.C943_02848 1.9e-245 854.7 Cytophagia purB GO:0003674,GO:0003824,GO:0004018,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 iAF1260.b1131,iBWG_1329.BWG_0979,iE2348C_1286.E2348C_1272,iEC042_1314.EC042_1202,iECABU_c1320.ECABU_c13450,iECDH10B_1368.ECDH10B_1203,iECP_1309.ECP_1126,iECUMN_1333.ECUMN_1375,iETEC_1333.ETEC_1255,iEcHS_1320.EcHS_A1251,iEcolC_1368.EcolC_2472,iJO1366.b1131,iJR904.b1131,iLF82_1304.LF82_1774,iNRG857_1313.NRG857_05460,iY75_1357.Y75_RS05905,ic_1306.c1510 Bacteria 47KAQ@768503,4NFY8@976,COG0015@1,COG0015@2 NA|NA|NA F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily MAG.T22.3_03727 1239962.C943_02846 1e-266 925.6 Cytophagia ychM ko:K03321 ko00000,ko02000 2.A.53.3 Bacteria 47MPC@768503,4NE9G@976,COG0659@1,COG0659@2 NA|NA|NA P COGs COG0659 Sulfate permease and related transporter (MFS superfamily) MAG.T22.3_03728 1239962.C943_02845 1.1e-167 595.9 Cytophagia Bacteria 47KEY@768503,4NFG3@976,COG4874@1,COG4874@2 NA|NA|NA S Amidinotransferase MAG.T22.3_03729 1239962.C943_02844 8.1e-160 569.7 Cytophagia Bacteria 47Y2Q@768503,4PME8@976,COG0823@1,COG0823@2 NA|NA|NA U Involved in the tonB-independent uptake of proteins MAG.T22.3_03730 1239962.C943_02843 7.4e-138 496.9 Cytophagia ko:K07004 ko00000 Bacteria 47P1B@768503,4NNX0@976,COG3204@1,COG3204@2 NA|NA|NA L pilus organization MAG.T22.3_03731 1239962.C943_02841 0.0 1586.6 Cytophagia clpC ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 47JFM@768503,4NE1J@976,COG0542@1,COG0542@2 NA|NA|NA O Belongs to the ClpA ClpB family MAG.T22.3_03732 1239962.C943_02840 2.5e-115 421.4 Cytophagia Bacteria 47Q4T@768503,4NM5H@976,COG0224@1,COG0224@2 NA|NA|NA C PFAM WbqC-like protein family MAG.T22.3_03733 1239962.C943_02839 1.7e-116 425.2 Cytophagia yciO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.7.87 ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 47KWK@768503,4NDZR@976,COG0009@1,COG0009@2 NA|NA|NA J Belongs to the SUA5 family MAG.T22.3_03734 1239962.C943_02838 1.1e-66 259.2 Cytophagia nudG GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55,3.6.1.65 ko:K03574,ko:K08320 ko00000,ko01000,ko03400 iE2348C_1286.E2348C_1887,iECP_1309.ECP_1705,iLF82_1304.LF82_1533,iNRG857_1313.NRG857_08815,iPC815.YPO2167,iSSON_1240.SSON_1397 Bacteria 47RZ7@768503,4NSND@976,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain MAG.T22.3_03735 1239962.C943_02837 4.6e-191 673.7 Cytophagia mltG ko:K07082 ko00000 Bacteria 47J93@768503,4NG17@976,COG1559@1,COG1559@2 NA|NA|NA S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation MAG.T22.3_03736 1239962.C943_02836 3.5e-70 270.8 Cytophagia ybgC ko:K07107 ko00000,ko01000 Bacteria 47Q99@768503,4NQGW@976,COG0824@1,COG0824@2 NA|NA|NA S TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family MAG.T22.3_03737 1239962.C943_02835 5.3e-162 577.0 Cytophagia rbn ko:K03466,ko:K07058 ko00000,ko03036 3.A.12 Bacteria 47KA8@768503,4NFY6@976,COG1295@1,COG1295@2 NA|NA|NA S TIGRFAM YihY family protein (not ribonuclease BN) MAG.T22.3_03738 1239962.C943_02834 0.0 1350.9 Cytophagia pta GO:0005575,GO:0005576 2.3.1.8 ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 Bacteria 47KUW@768503,4NGX5@976,COG0280@1,COG0280@2,COG0857@1,COG0857@2 NA|NA|NA C belongs to the CobB CobQ family MAG.T22.3_03739 1239962.C943_02833 5.3e-164 583.6 Cytophagia Bacteria 47KXZ@768503,4NF4H@976,COG1853@1,COG1853@2 NA|NA|NA S PFAM Flavin reductase like domain MAG.T22.3_03740 1239962.C943_02832 4.5e-160 570.5 Cytophagia Bacteria 47NJC@768503,4NHXV@976,COG3568@1,COG3568@2 NA|NA|NA S PFAM Endonuclease Exonuclease phosphatase MAG.T22.3_03743 1239962.C943_00771 3.2e-188 664.8 Cytophagia Bacteria 47R8P@768503,4NTB7@976,COG4942@1,COG4942@2 NA|NA|NA D peptidase MAG.T22.3_03744 1239962.C943_00772 0.0 2474.9 Cytophagia Bacteria 47U4G@768503,4NI5F@976,COG3291@1,COG3291@2 NA|NA|NA L ATPase involved in DNA repair MAG.T22.3_03745 1239962.C943_00773 0.0 1941.8 Cytophagia ko:K09946 ko00000 Bacteria 47NKA@768503,4NHE4@976,COG3422@1,COG3422@2 NA|NA|NA H Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX MAG.T22.3_03746 1239962.C943_00774 0.0 2207.9 Cytophagia Bacteria 47N9M@768503,4NF69@976,COG3299@1,COG3299@2 NA|NA|NA S homolog of phage Mu protein gp47 MAG.T22.3_03747 1239962.C943_00775 2.7e-54 218.0 Bacteroidetes ko:K06903 ko00000 Bacteria 4NSKN@976,COG3628@1,COG3628@2 NA|NA|NA S Phage baseplate assembly protein W MAG.T22.3_03748 1443665.JACA01000013_gene4232 2.8e-29 134.4 Aquimarina Bacteria 1I4Y4@117743,2YM39@290174,4NSCZ@976,COG4104@1,COG4104@2 NA|NA|NA S PAAR motif MAG.T22.3_03749 1239962.C943_00777 0.0 1119.8 Cytophagia Bacteria 47XNK@768503,4NFPB@976,COG3501@1,COG3501@2 NA|NA|NA S Rhs element Vgr protein MAG.T22.3_03750 1239962.C943_00778 1e-133 482.6 Cytophagia Bacteria 47R3Z@768503,4NJV3@976,COG1652@1,COG1652@2 NA|NA|NA S LysM domain MAG.T22.3_03752 1239962.C943_00780 3.8e-87 327.4 Cytophagia Bacteria 2DMQT@1,32T2H@2,47RJF@768503,4NN19@976 NA|NA|NA S T4-like virus tail tube protein gp19 MAG.T22.3_03753 1239962.C943_00781 9.7e-79 299.3 Cytophagia Bacteria 2DB76@1,2Z7JZ@2,47QC1@768503,4NQDC@976 NA|NA|NA S T4-like virus tail tube protein gp19 MAG.T22.3_03754 1239962.C943_00782 4.5e-266 923.3 Cytophagia ko:K06907 ko00000 Bacteria 47KYE@768503,4NEKK@976,COG3497@1,COG3497@2 NA|NA|NA S Phage tail sheath C-terminal domain MAG.T22.3_03756 1239962.C943_00784 5.5e-101 373.6 Bacteroidetes Bacteria 2C0BR@1,32Z3H@2,4NU9A@976 NA|NA|NA S Protein of unknown function (DUF4255) MAG.T22.3_03757 1239962.C943_00785 2e-109 401.7 Bacteroidetes Bacteria 4P5QB@976,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon MAG.T22.3_03758 1239962.C943_00786 2.9e-246 857.4 Cytophagia Bacteria 28H89@1,2Z7K8@2,47M3Y@768503,4NEKX@976 NA|NA|NA MAG.T22.3_03759 1239962.C943_00787 1.5e-59 235.3 Cytophagia rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 ko:K02834 ko00000,ko03009 Bacteria 47Q35@768503,4NSQJ@976,COG0858@1,COG0858@2 NA|NA|NA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA MAG.T22.3_03760 1239962.C943_00788 1.1e-203 715.7 Cytophagia lolE ko:K09808,ko:K09815 ko02010,map02010 M00242,M00255 ko00000,ko00001,ko00002,ko02000 3.A.1.125,3.A.1.15.3,3.A.1.15.5 Bacteria 47M0Q@768503,4NG04@976,COG4591@1,COG4591@2 NA|NA|NA M ABC-type transport system involved in lipoprotein release permease component MAG.T22.3_03761 1239962.C943_00789 0.0 1369.4 Cytophagia Bacteria 47MWY@768503,4NHS5@976,COG0823@1,COG0823@2,COG1506@1,COG1506@2 NA|NA|NA EU Peptidase S9 prolyl oligopeptidase active site domain protein MAG.T22.3_03762 1239962.C943_00790 1.2e-104 386.0 Cytophagia Bacteria 47P9C@768503,4NHHK@976,COG0637@1,COG0637@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase MAG.T22.3_03763 1239962.C943_00791 3.3e-147 527.7 Cytophagia nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1988 Bacteria 47JJ8@768503,4NDXF@976,COG0157@1,COG0157@2 NA|NA|NA H Belongs to the NadC ModD family MAG.T22.3_03764 1239962.C943_00792 3.7e-76 290.8 Bacteroidetes Bacteria 2E4AG@1,32Z66@2,4NYIR@976 NA|NA|NA S Domain of unknown function (DUF4783) MAG.T22.3_03765 1239962.C943_00793 1.1e-289 1001.9 Cytophagia gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_3895,iJN678.yibO,iJN746.PP_5056 Bacteria 47K1F@768503,4NEQT@976,COG0696@1,COG0696@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate MAG.T22.3_03766 1189612.A33Q_4265 2.2e-41 175.6 Cytophagia Bacteria 29KB5@1,33KES@2,47ST6@768503,4NZ0G@976 NA|NA|NA MAG.T22.3_03767 1239962.C943_00796 3.8e-271 940.3 Cytophagia arsB Bacteria 47KPC@768503,4NGWD@976,COG1055@1,COG1055@2 NA|NA|NA P Citrate transporter MAG.T22.3_03768 1239962.C943_00797 6.3e-232 809.7 Cytophagia gdhA2 1.4.1.3 ko:K00261 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47KWD@768503,4NG6Y@976,COG0334@1,COG0334@2 NA|NA|NA E Glu Leu Phe Val dehydrogenase MAG.T22.3_03769 1239962.C943_00798 9.9e-197 692.6 Cytophagia anmK 2.7.1.170,4.2.1.126 ko:K07106,ko:K09001 ko00520,ko01100,map00520,map01100 R08555 RC00397,RC00746 ko00000,ko00001,ko01000 Bacteria 47NI9@768503,4NFZU@976,COG2377@1,COG2377@2 NA|NA|NA O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling MAG.T22.3_03770 1239962.C943_00799 1.7e-128 465.3 Cytophagia coaX 2.7.1.33,6.3.4.15 ko:K01947,ko:K03525 ko00770,ko00780,ko01100,map00770,map00780,map01100 M00120 R01074,R02971,R03018,R04391,R05145 RC00002,RC00017,RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000 Bacteria 47K36@768503,4NE9E@976,COG1521@1,COG1521@2 NA|NA|NA H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis MAG.T22.3_03771 1239962.C943_00800 5.2e-237 826.6 Cytophagia Bacteria 47N37@768503,4NEP1@976,COG2067@1,COG2067@2 NA|NA|NA I membrane MAG.T22.3_03772 1239962.C943_00801 5.4e-242 843.2 Cytophagia Bacteria 47MJ6@768503,4NF7U@976,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat protein MAG.T22.3_03773 1239962.C943_00802 6.5e-93 346.7 Cytophagia lptC ko:K09774,ko:K11719 ko00000,ko02000 1.B.42.1 Bacteria 47R6J@768503,4NRIN@976,COG3117@1,COG3117@2 NA|NA|NA S Lipopolysaccharide-assembly, LptC-related MAG.T22.3_03774 1239962.C943_00804 7.8e-225 786.2 Cytophagia tlyC Bacteria 47KQX@768503,4NG0I@976,COG1253@1,COG1253@2 NA|NA|NA S CBS domain MAG.T22.3_03775 1239962.C943_00805 0.0 1346.6 Cytophagia ppiD 5.2.1.8 ko:K01802,ko:K03769,ko:K03770 ko00000,ko01000,ko03110 Bacteria 47KBN@768503,4NDZZ@976,COG0760@1,COG0760@2 NA|NA|NA O peptidylprolyl isomerase MAG.T22.3_03776 1239962.C943_00806 3.5e-39 167.2 Cytophagia ybeD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K09158 ko00000 Bacteria 47S9P@768503,4P9XR@976,COG2921@1,COG2921@2 NA|NA|NA S Protein of unknown function (DUF493) MAG.T22.3_03777 1239962.C943_00807 1.2e-35 155.2 Cytophagia phhB 4.2.1.96 ko:K01724 ko00790,map00790 R04734 RC01208 ko00000,ko00001,ko01000,ko04147 Bacteria 47RW0@768503,4NS9U@976,COG2154@1,COG2154@2 NA|NA|NA H PFAM Pterin 4 alpha carbinolamine dehydratase MAG.T22.3_03778 1239962.C943_00808 4.1e-122 444.1 Cytophagia rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 47JDW@768503,4NFQM@976,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA MAG.T22.3_03779 1239962.C943_00809 8.5e-159 566.2 Bacteroidetes Bacteria 4NM2E@976,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 MAG.T22.3_03780 1239962.C943_00810 4e-89 334.0 Cytophagia ptpA 3.1.3.48 ko:K01104,ko:K20945 ko05111,map05111 ko00000,ko00001,ko01000 Bacteria 47R52@768503,4NNQZ@976,COG0394@1,COG0394@2 NA|NA|NA T Low molecular weight phosphotyrosine protein phosphatase MAG.T22.3_03781 1239962.C943_00811 7.1e-161 573.2 Cytophagia yniA GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 Bacteria 47K5K@768503,4NEQY@976,COG3001@1,COG3001@2 NA|NA|NA G Fructosamine kinase MAG.T22.3_03782 1239962.C943_00812 3.5e-225 787.3 Cytophagia lysC 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 47JAD@768503,4NF0M@976,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family MAG.T22.3_03783 1239962.C943_00813 3e-182 644.4 Cytophagia fbp GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 ko:K03841 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910 M00003,M00165,M00167,M00344 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000,ko04147 iUTI89_1310.UTI89_C4836,ic_1306.c5329 Bacteria 47KNQ@768503,4NG06@976,COG0158@1,COG0158@2 NA|NA|NA G D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 MAG.T22.3_03784 1121859.KB890739_gene2132 5.6e-15 87.0 Cytophagia Bacteria 2DRQJ@1,33CMW@2,47T3Q@768503,4NYAM@976 NA|NA|NA MAG.T22.3_03785 1239962.C943_00815 2.4e-69 268.1 Cytophagia Bacteria 2DEYG@1,2ZPSM@2,47PWR@768503,4NNJW@976 NA|NA|NA MAG.T22.3_03786 1239962.C943_00816 9.9e-80 302.8 Cytophagia engB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03978 ko00000,ko03036 Bacteria 47P6H@768503,4NEA9@976,COG0218@1,COG0218@2 NA|NA|NA D Necessary for normal cell division and for the maintenance of normal septation MAG.T22.3_03787 1239962.C943_00817 6.3e-131 473.4 Cytophagia menG 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 Bacteria 47JXK@768503,4NEDR@976,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) MAG.T22.3_03788 1239962.C943_00818 3.9e-126 457.6 Cytophagia porT Bacteria 2C52N@1,2Z7U1@2,47PC8@768503,4NEZW@976 NA|NA|NA S Outer membrane protein beta-barrel domain MAG.T22.3_03789 1239962.C943_00819 2.3e-133 481.5 Cytophagia ygdL GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0030955,GO:0031402,GO:0031420,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029,ko:K22132 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07459 RC00043 ko00000,ko00001,ko01000,ko03016 Bacteria 47KQ6@768503,4NEKB@976,COG1179@1,COG1179@2 NA|NA|NA H ThiF family MAG.T22.3_03790 1239962.C943_00820 2.3e-108 398.3 Cytophagia ko:K03424 ko00000,ko01000 Bacteria 47QPS@768503,4NSGW@976,COG0084@1,COG0084@2 NA|NA|NA L TatD related DNase MAG.T22.3_03791 1239962.C943_00821 7.5e-195 686.4 Cytophagia celE Bacteria 47KFA@768503,4NGBI@976,COG1473@1,COG1473@2 NA|NA|NA S PFAM Peptidase family M20 M25 M40 MAG.T22.3_03793 1239962.C943_00825 0.0 1580.1 Cytophagia 3.2.1.40 ko:K05989 ko00000,ko01000 Bacteria 47N0U@768503,4NHUB@976,COG3408@1,COG3408@2 NA|NA|NA G Glycogen debranching enzyme MAG.T22.3_03794 1239962.C943_00826 4.4e-78 297.4 Bacteria Bacteria COG4194@1,COG4194@2 NA|NA|NA K SdpI/YhfL protein family MAG.T22.3_03795 1239962.C943_00828 0.0 1509.2 Cytophagia Bacteria 47JK5@768503,4NFQ6@976,COG2091@1,COG2091@2 NA|NA|NA H lysine biosynthetic process via aminoadipic acid MAG.T22.3_03796 1239962.C943_00830 1.9e-138 498.4 Bacteria Bacteria COG0810@1,COG0810@2 NA|NA|NA M energy transducer activity MAG.T22.3_03797 1239962.C943_00831 3.3e-250 870.5 Cytophagia yahJ GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016810,GO:0016814,GO:0044424,GO:0044444,GO:0044464 Bacteria 47NXG@768503,4NHHX@976,COG0402@1,COG0402@2 NA|NA|NA F deaminase with metallo-dependent hydrolase domain MAG.T22.3_03798 1239962.C943_00832 2.9e-84 317.8 Cytophagia vsr ko:K07458 ko00000,ko01000,ko03400 Bacteria 47Q4A@768503,4NQEH@976,COG3727@1,COG3727@2 NA|NA|NA L May nick specific sequences that contain T G mispairs resulting from m5C-deamination MAG.T22.3_03799 1239962.C943_00833 6.7e-192 676.4 Cytophagia Bacteria 47MAP@768503,4NEUZ@976,COG1262@1,COG1262@2 NA|NA|NA C PFAM Formylglycine-generating sulfatase enzyme MAG.T22.3_03800 1239962.C943_00834 1e-248 865.5 Cytophagia Bacteria 47JCP@768503,4NF9M@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.3_03801 1239962.C943_00835 1e-162 579.3 Cytophagia 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 R01394 RC00511 ko00000,ko00001,ko01000 Bacteria 47K7Z@768503,4NG74@976,COG3622@1,COG3622@2 NA|NA|NA G PFAM Xylose isomerase-like TIM barrel MAG.T22.3_03802 880070.Cycma_0714 1.9e-200 705.7 Bacteroidetes ko:K02021,ko:K18217 ko02010,map02010 M00635 ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1,3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 Bacteria 4NEWK@976,COG1132@1,COG1132@2 NA|NA|NA V COG1132 ABC-type multidrug transport system, ATPase and permease components MAG.T22.3_03803 1123057.P872_14895 1.7e-62 246.9 Cytophagia flhB ko:K02401,ko:K13820 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 3.A.6.2 Bacteria 47TS7@768503,4NKEP@976,COG1377@1,COG1377@2 NA|NA|NA NU O-antigen ligase like membrane protein MAG.T22.3_03804 1239962.C943_01353 0.0 1233.4 Bacteria wzc GO:0000271,GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016301,GO:0016310,GO:0016462,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0036211,GO:0038083,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046377,GO:0046777,GO:0071704,GO:0071944,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 ko:K16692 ko00000,ko01000,ko01001 Bacteria COG0489@1,COG0489@2,COG3206@1,COG3206@2 NA|NA|NA M extracellular polysaccharide biosynthetic process MAG.T22.3_03805 1239962.C943_01354 2.2e-127 461.8 Cytophagia wza ko:K01991 ko02026,map02026 ko00000,ko00001,ko02000 1.B.18 Bacteria 47TY2@768503,4NFXJ@976,COG1596@1,COG1596@2 NA|NA|NA M Polysaccharide biosynthesis/export protein MAG.T22.3_03806 1239962.C943_01355 0.0 2471.4 Cytophagia pksM3 ko:K13611,ko:K13614,ko:K15675 ko00000,ko01004,ko01008 Bacteria 47JBY@768503,4NDV5@976,COG1020@1,COG1020@2 NA|NA|NA Q Amino acid adenylation domain MAG.T22.3_03807 1239962.C943_01357 0.0 3185.2 Cytophagia ko:K13611 ko00000,ko01004,ko01008 Bacteria 47K9U@768503,4NDV5@976,COG1020@1,COG1020@2,COG3321@1,COG3321@2 NA|NA|NA Q Acyl transferase domain in polyketide synthase (PKS) enzymes. MAG.T22.3_03808 1239962.C943_01358 0.0 2581.6 Cytophagia bcsA GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016020,GO:0016051,GO:0030243,GO:0030244,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0051273,GO:0051274,GO:0071704,GO:0071944,GO:0090540,GO:1901576 2.4.1.12,3.2.1.23,3.2.1.35,3.2.1.51,3.2.1.97 ko:K00694,ko:K01190,ko:K01197,ko:K01206,ko:K17624,ko:K20541 ko00052,ko00500,ko00511,ko00531,ko00600,ko01100,ko02026,map00052,map00500,map00511,map00531,map00600,map01100,map02026 M00076,M00077 R01105,R01678,R02889,R03355,R04783,R06114,R07824,R07825,R10905 RC00005,RC00049,RC00452 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko01003,ko02000,ko02042,ko04147 4.D.3.1.2,4.D.3.1.5,4.D.3.1.6 GH101,GH29,GT2 Bacteria 47KAY@768503,4NEK9@976,COG1215@1,COG1215@2,COG3250@1,COG3250@2,COG4124@1,COG4124@2 NA|NA|NA M Cellulose synthase MAG.T22.3_03809 1239962.C943_01360 3.7e-190 671.0 Cytophagia Bacteria 47JP4@768503,4NHRV@976,COG3250@1,COG3250@2 NA|NA|NA G Glycosyl hydrolases family 2, TIM barrel domain MAG.T22.3_03810 1239962.C943_01361 3.8e-123 447.6 Cytophagia Bacteria 47M1F@768503,4NFM1@976,COG1215@1,COG1215@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T22.3_03811 1239962.C943_01362 4e-265 920.2 Cytophagia 2.4.1.12 ko:K00694 ko00500,ko01100,ko02026,map00500,map01100,map02026 R02889 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.3.1.2,4.D.3.1.5,4.D.3.1.6 GT2 Bacteria 47MJK@768503,4NEK9@976,COG1215@1,COG1215@2 NA|NA|NA M glycosyl transferase family 2 MAG.T22.3_03812 1239962.C943_01363 7.8e-288 995.7 Cytophagia Bacteria 47KC5@768503,4NHSX@976,COG0348@1,COG0348@2 NA|NA|NA C 4Fe-4S dicluster domain MAG.T22.3_03813 1239962.C943_01364 1.1e-258 898.7 Cytophagia norW GO:0000166,GO:0000302,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010035,GO:0015044,GO:0016491,GO:0016730,GO:0016731,GO:0017144,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042493,GO:0042737,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0044270,GO:0044424,GO:0044464,GO:0046209,GO:0046210,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071241,GO:0071731,GO:0071732,GO:0072593,GO:0097159,GO:0097366,GO:1901265,GO:1901363,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:2001057 1.18.1.1,1.7.1.15 ko:K00362,ko:K05297,ko:K12265 ko00071,ko00910,ko01120,ko05132,map00071,map00910,map01120,map05132 M00530 R00787,R02000 RC00176 ko00000,ko00001,ko00002,ko01000 iEcHS_1320.EcHS_A2847,iSSON_1240.SSON_2855 Bacteria 47JW2@768503,4NET1@976,COG0446@1,COG0446@2 NA|NA|NA S Pyridine nucleotide-disulphide oxidoreductase MAG.T22.3_03814 1239962.C943_01365 1.6e-140 505.4 Cytophagia Bacteria 47KFE@768503,4NIT2@976,COG0398@1,COG0398@2 NA|NA|NA S Protein of unknown function, DUF547 MAG.T22.3_03815 1239962.C943_01367 8.1e-157 559.7 Cytophagia glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 47MFN@768503,4NGI1@976,COG0584@1,COG0584@2 NA|NA|NA C PFAM Glycerophosphoryl diester phosphodiesterase MAG.T22.3_03816 1239962.C943_01368 1.3e-240 838.6 Cytophagia rimO GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 ko:K14441 R10652 RC00003,RC03217 ko00000,ko01000,ko03009 Bacteria 47JJ2@768503,4NEJK@976,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 MAG.T22.3_03817 1239962.C943_01369 3.5e-37 160.6 Cytophagia Bacteria 2E3VP@1,32YSV@2,47S3V@768503,4NV28@976 NA|NA|NA MAG.T22.3_03818 1239962.C943_01370 3.1e-82 311.2 Cytophagia Bacteria 47RP1@768503,4NQYA@976,COG2207@1,COG2207@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein MAG.T22.3_03819 1239962.C943_01371 0.0 1319.7 Cytophagia bfmBA 1.2.4.1,1.2.4.4 ko:K00161,ko:K00167,ko:K11381,ko:K21416,ko:K21417 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 47KFY@768503,4NE71@976,COG0022@1,COG0022@2,COG1071@1,COG1071@2 NA|NA|NA C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit MAG.T22.3_03820 1239962.C943_01372 1.7e-100 372.1 Cytophagia Bacteria 47Q1A@768503,4NNM9@976,COG4636@1,COG4636@2 NA|NA|NA S Putative restriction endonuclease MAG.T22.3_03821 1239962.C943_01373 3.4e-126 457.6 Cytophagia Bacteria 2CJYY@1,33ANY@2,47T05@768503,4NXWC@976 NA|NA|NA MAG.T22.3_03822 1239962.C943_01374 1.4e-110 405.6 Cytophagia Bacteria 47S4Q@768503,4NV5A@976,COG4636@1,COG4636@2 NA|NA|NA S Putative restriction endonuclease MAG.T22.3_03823 866536.Belba_0619 3.8e-15 89.0 Cytophagia Bacteria 2EQCS@1,33HYU@2,47SPP@768503,4NXR7@976 NA|NA|NA MAG.T22.3_03824 1239962.C943_01375 6.2e-91 340.1 Bacteroidetes rlpA ko:K03642 ko00000 Bacteria 4NSF1@976,COG0797@1,COG0797@2 NA|NA|NA M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides MAG.T22.3_03825 1239962.C943_01377 9.1e-223 779.2 Cytophagia sbcD ko:K03547 ko00000,ko03400 Bacteria 47MGK@768503,4NEET@976,COG0420@1,COG0420@2 NA|NA|NA L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity MAG.T22.3_03826 1239962.C943_01378 0.0 1678.7 Cytophagia sbcC ko:K03546 ko00000,ko03400 Bacteria 47N6H@768503,4NH9H@976,COG0419@1,COG0419@2 NA|NA|NA L ATPase involved in DNA repair MAG.T22.3_03827 1239962.C943_01379 4e-223 780.4 Cytophagia ko:K07133 ko00000 Bacteria 47U2B@768503,4NGFI@976,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) MAG.T22.3_03828 1239962.C943_01381 8.2e-301 1038.9 Cytophagia Bacteria 47NVH@768503,4NF9K@976,COG1409@1,COG1409@2 NA|NA|NA S N terminal of Calcineurin-like phosphoesterase MAG.T22.3_03829 1239962.C943_01383 7.1e-248 862.8 Cytophagia pepP GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 ko:K01262 ko00000,ko01000,ko01002 Bacteria 47MY8@768503,4NI0S@976,COG0006@1,COG0006@2 NA|NA|NA E Belongs to the peptidase M24B family MAG.T22.3_03830 1239962.C943_01385 9.5e-284 982.2 Cytophagia pafA GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 47JP2@768503,4NE94@976,COG1524@1,COG1524@2 NA|NA|NA P type I phosphodiesterase nucleotide pyrophosphatase MAG.T22.3_03831 1239962.C943_01386 3.7e-234 817.0 Cytophagia hmgA 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 Bacteria 47JCV@768503,4NEYZ@976,COG3508@1,COG3508@2 NA|NA|NA Q Homogentisate 12-dioxygenase MAG.T22.3_03832 1239962.C943_01388 1.2e-146 525.8 Cytophagia Bacteria 47JXY@768503,4NHP5@976,COG2273@1,COG2273@2 NA|NA|NA G Glycoside hydrolase family 16 MAG.T22.3_03833 1239962.C943_01389 2.1e-138 498.4 Cytophagia ubiA 2.5.1.39,2.5.1.42 ko:K03179,ko:K17105 ko00130,ko00564,ko01100,ko01110,map00130,map00564,map01100,map01110 M00117 R04520,R05000,R05615 RC00209,RC01171,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 47MCK@768503,4NGNA@976,COG0382@1,COG0382@2 NA|NA|NA H PFAM UbiA prenyltransferase MAG.T22.3_03834 1239962.C943_01390 1.9e-225 788.1 Cytophagia ko:K07133 ko00000 Bacteria 47P2P@768503,4NE3E@976,COG1373@1,COG1373@2 NA|NA|NA S AAA domain MAG.T22.3_03835 1239962.C943_01391 1.2e-100 372.5 Cytophagia purN 2.1.2.2,6.3.2.6,6.3.4.13 ko:K11175,ko:K13713 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04144,R04325,R04326,R04591 RC00026,RC00064,RC00090,RC00162,RC00166,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 Bacteria 47KTP@768503,4NNZP@976,COG0299@1,COG0299@2 NA|NA|NA F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate MAG.T22.3_03836 1239962.C943_01392 9.5e-278 962.2 Cytophagia purH 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47JQT@768503,4NEZD@976,COG0138@1,COG0138@2 NA|NA|NA F Bifunctional purine biosynthesis protein PurH MAG.T22.3_03837 1239962.C943_04609 2.7e-160 571.2 Cytophagia dlhH2 3.1.1.102,3.1.1.45 ko:K01061,ko:K21105 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222,R11541 RC00020,RC00041,RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 Bacteria 47KK1@768503,4NE8V@976,COG0412@1,COG0412@2 NA|NA|NA Q Dienelactone hydrolase family MAG.T22.3_03838 1239962.C943_04610 0.0 1813.1 Cytophagia ko:K14054 ko00000 Bacteria 47MVZ@768503,4NF3D@976,COG2866@1,COG2866@2 NA|NA|NA E Zinc carboxypeptidase MAG.T22.3_03839 1239962.C943_04615 8.4e-276 955.7 Cytophagia pqaA Bacteria 47KB9@768503,4NI0U@976,COG4287@1,COG4287@2 NA|NA|NA S PhoPQ-activated pathogenicity-related protein MAG.T22.3_03840 1239962.C943_04616 1e-116 426.4 Cytophagia ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 1.A.30.1 Bacteria 47XQW@768503,4NHDJ@976,COG1360@1,COG1360@2 NA|NA|NA N OmpA family MAG.T22.3_03841 1239962.C943_04617 4.9e-215 753.4 Cytophagia mro 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0282 Bacteria 47KAR@768503,4NF5G@976,COG2017@1,COG2017@2 NA|NA|NA G Converts alpha-aldose to the beta-anomer MAG.T22.3_03842 1239962.C943_04618 4.9e-125 453.8 Cytophagia Bacteria 47KW0@768503,4NFYS@976,COG3485@1,COG3485@2 NA|NA|NA Q Dioxygenase MAG.T22.3_03844 1239962.C943_04620 0.0 1182.5 Cytophagia 2.5.1.56 ko:K01654 ko00520,ko01100,map00520,map01100 R01804,R04435 RC00159 ko00000,ko00001,ko01000 Bacteria 47N77@768503,4NGW0@976,COG0517@1,COG0517@2 NA|NA|NA S Domain in cystathionine beta-synthase and other proteins. MAG.T22.3_03845 1239962.C943_04621 2.8e-216 757.7 Cytophagia astE 3.5.1.96 ko:K05526 ko00330,ko01100,map00330,map01100 R00411 RC00064,RC00090 ko00000,ko00001,ko01000 Bacteria 47PWT@768503,4NHWW@976,COG2988@1,COG2988@2 NA|NA|NA E Succinylglutamate desuccinylase / Aspartoacylase family MAG.T22.3_03846 1239962.C943_04622 1.6e-86 325.5 Bacteroidetes Bacteria 4NUD2@976,COG3832@1,COG3832@2 NA|NA|NA S Polyketide cyclase / dehydrase and lipid transport MAG.T22.3_03847 1239962.C943_04623 1.2e-89 335.9 Cytophagia Bacteria 47XMM@768503,4NPI3@976,COG0664@1,COG0664@2 NA|NA|NA T Cyclic nucleotide-binding domain MAG.T22.3_03848 1239962.C943_04624 1.2e-88 332.4 Cytophagia dcdA 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 Bacteria 47P6P@768503,4NM48@976,COG2131@1,COG2131@2 NA|NA|NA F PFAM Cytidine and deoxycytidylate deaminase zinc-binding region MAG.T22.3_03849 1239962.C943_04625 7.4e-178 629.8 Cytophagia murB 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 Bacteria 47KJJ@768503,4NE78@976,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation MAG.T22.3_03850 1239962.C943_04626 1.1e-175 622.5 Cytophagia ko:K06987 ko00000 Bacteria 47KAM@768503,4NE8S@976,COG3608@1,COG3608@2 NA|NA|NA S PFAM Succinylglutamate desuccinylase Aspartoacylase family MAG.T22.3_03851 1239962.C943_04627 8.9e-139 499.6 Cytophagia Bacteria 47PJ4@768503,4NMKR@976,COG3000@1,COG3000@2 NA|NA|NA I Fatty acid hydroxylase superfamily MAG.T22.3_03852 1123057.P872_18295 4.2e-45 188.0 Cytophagia Bacteria 2F1J8@1,33UJN@2,47UTE@768503,4P2IC@976 NA|NA|NA MAG.T22.3_03853 1239962.C943_04630 0.0 1156.4 Cytophagia pmmB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2,5.4.2.8 ko:K01835,ko:K01840 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114,M00549 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 47KI8@768503,4NFU7@976,COG1109@1,COG1109@2 NA|NA|NA G Phosphoglucomutase phosphomannomutase alpha beta alpha domain I MAG.T22.3_03855 1239962.C943_04632 5e-207 726.9 Cytophagia hpd GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 ko:K00457,ko:K16421 ko00130,ko00261,ko00350,ko00360,ko01055,ko01100,ko01130,map00130,map00261,map00350,map00360,map01055,map01100,map01130 M00044 R01372,R02521,R06632 RC00505,RC00738,RC01471 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47KCH@768503,4NFI7@976,COG3185@1,COG3185@2 NA|NA|NA E PFAM Glyoxalase bleomycin resistance protein dioxygenase MAG.T22.3_03856 1239962.C943_04633 1.6e-180 638.6 Cytophagia plsB 2.3.1.15 ko:K00630,ko:K00631,ko:K14598 ko00561,ko00564,ko00906,ko01100,ko01110,map00561,map00564,map00906,map01100,map01110 M00089 R00851,R07545,R07547,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 47NT5@768503,4NK8Z@976,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases MAG.T22.3_03857 1239962.C943_04634 4.1e-156 557.4 Cytophagia ko:K03453 ko00000 2.A.28 Bacteria 47PJM@768503,4NEIM@976,COG0385@1,COG0385@2 NA|NA|NA S SBF-like CPA transporter family (DUF4137) MAG.T22.3_03858 1239962.C943_04635 7.6e-250 869.4 Cytophagia pntB 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 47MXN@768503,4NHGZ@976,COG1282@1,COG1282@2 NA|NA|NA C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane MAG.T22.3_03859 1239962.C943_04636 9.4e-47 192.6 Cytophagia pntAA 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 47RF1@768503,4NT78@976,COG3288@1,COG3288@2 NA|NA|NA C 4TM region of pyridine nucleotide transhydrogenase, mitoch MAG.T22.3_03860 1239962.C943_04637 8.1e-202 709.5 Cytophagia pntA GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0097159,GO:1901265,GO:1901363 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 47KX8@768503,4NGH1@976,COG3288@1,COG3288@2 NA|NA|NA C Alanine dehydrogenase/PNT, C-terminal domain MAG.T22.3_03861 1239962.C943_04638 8.3e-138 496.5 Bacteroidetes Bacteria 4NFJP@976,COG0726@1,COG0726@2 NA|NA|NA G polysaccharide deacetylase MAG.T22.3_03862 1239962.C943_04639 0.0 1182.9 Cytophagia Bacteria 47JQ2@768503,4NEF2@976,COG2303@1,COG2303@2 NA|NA|NA E PFAM glucose-methanol-choline oxidoreductase MAG.T22.3_03863 1239962.C943_04640 6.1e-108 396.7 Cytophagia Bacteria 28KSE@1,2ZBRS@2,47P8I@768503,4NNCR@976 NA|NA|NA S Gluconate 2-dehydrogenase subunit 3 MAG.T22.3_03864 1239962.C943_04641 1.1e-109 402.5 Bacteroidetes Bacteria 2EIHE@1,33C8S@2,4NY6K@976 NA|NA|NA MAG.T22.3_03865 1239962.C943_01474 2e-165 588.2 Cytophagia Bacteria 47KMB@768503,4NFCW@976,COG3291@1,COG3291@2 NA|NA|NA M C-terminal domain of CHU protein family MAG.T22.3_03866 1239962.C943_01473 3.9e-72 277.3 Cytophagia yuxK Bacteria 47R74@768503,4NQ93@976,COG3011@1,COG3011@2 NA|NA|NA S Protein of unknown function, DUF393 MAG.T22.3_03867 1239962.C943_01472 4.9e-119 433.7 Cytophagia yadF 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 iNJ661.Rv3273 Bacteria 47MBG@768503,4NEJT@976,COG0288@1,COG0288@2 NA|NA|NA P Reversible hydration of carbon dioxide MAG.T22.3_03868 1239962.C943_01471 1e-159 569.3 Cytophagia Bacteria 47KC0@768503,4NE7D@976,COG0627@1,COG0627@2 NA|NA|NA S esterase MAG.T22.3_03869 1239962.C943_01470 2.2e-193 681.4 Cytophagia Bacteria 47UI9@768503,4PI2A@976,COG4772@1,COG4772@2 NA|NA|NA P Type IX secretion system membrane protein PorP/SprF MAG.T22.3_03870 1239962.C943_01469 0.0 3148.6 Cytophagia Bacteria 47MNQ@768503,4NDZC@976,COG3291@1,COG3291@2 NA|NA|NA O SprB repeat MAG.T22.3_03871 886379.AEWI01000007_gene834 7e-12 76.3 Bacteroidetes Bacteria 2EV34@1,33NI5@2,4P7MA@976 NA|NA|NA MAG.T22.3_03872 1270196.JCKI01000002_gene182 1.1e-10 72.4 Bacteria Bacteria COG1848@1,COG1848@2 NA|NA|NA G Toxic component of a toxin-antitoxin (TA) module. An RNase MAG.T22.3_03874 1239962.C943_01464 2.6e-129 468.8 Cytophagia Bacteria 47K8U@768503,4NIGK@976,COG3078@1,COG3078@2 NA|NA|NA P GTPase activator activity MAG.T22.3_03875 1121481.AUAS01000018_gene444 1.8e-23 115.2 Cytophagia Bacteria 47S0X@768503,4NW7E@976,COG3668@1,COG3668@2 NA|NA|NA S ParE toxin of type II toxin-antitoxin system, parDE MAG.T22.3_03876 1121481.AUAS01000018_gene445 8e-11 72.8 Cytophagia Bacteria 2A95X@1,30YAH@2,47WPU@768503,4PC26@976 NA|NA|NA MAG.T22.3_03878 927658.AJUM01000042_gene1546 2.5e-28 131.3 Bacteroidia Bacteria 2FT8S@200643,4NYUJ@976,COG1708@1,COG1708@2 NA|NA|NA S Nucleotidyltransferase domain MAG.T22.3_03879 1521187.JPIM01000076_gene1203 4e-20 104.4 Bacteria Bacteria COG2250@1,COG2250@2 NA|NA|NA S HEPN domain MAG.T22.3_03880 1239962.C943_01463 1.1e-234 819.3 Cytophagia Bacteria 47K8U@768503,4NIGK@976,COG3078@1,COG3078@2 NA|NA|NA P GTPase activator activity MAG.T22.3_03881 1239962.C943_01462 3.6e-158 564.3 Cytophagia Bacteria 47PEK@768503,4NMA2@976,COG3712@1,COG3712@2 NA|NA|NA PT Domain of unknown function (DUF4974) MAG.T22.3_03882 1239962.C943_01461 4.2e-85 320.9 Cytophagia ko:K03088 ko00000,ko03021 Bacteria 47PH5@768503,4NNBY@976,COG1595@1,COG1595@2 NA|NA|NA K RNA polymerase sigma factor, sigma-70 family MAG.T22.3_03883 1239962.C943_01458 9e-142 509.6 Cytophagia CP_0807 ko:K09125 ko00000 Bacteria 47J8X@768503,4NFP3@976,COG1738@1,COG1738@2 NA|NA|NA S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage MAG.T22.3_03884 1239962.C943_01457 1.2e-174 619.0 Cytophagia rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 47KGX@768503,4NE1K@976,COG1234@1,COG1234@2 NA|NA|NA S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA MAG.T22.3_03885 1239962.C943_01456 2.8e-61 241.1 Cytophagia ko:K04749 ko00000,ko03021 Bacteria 47R1F@768503,4NTPB@976,COG1366@1,COG1366@2 NA|NA|NA T Belongs to the anti-sigma-factor antagonist family MAG.T22.3_03886 1239962.C943_01455 6.4e-176 623.2 Cytophagia purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 ko:K01923,ko:K03566,ko:K13713 ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 47JZR@768503,4NF1Z@976,COG0152@1,COG0152@2 NA|NA|NA F PFAM SAICAR synthetase MAG.T22.3_03887 1239962.C943_01454 4.3e-46 192.2 Cytophagia Bacteria 47PSU@768503,4NMDX@976,COG2849@1,COG2849@2 NA|NA|NA S PFAM MORN repeat variant MAG.T22.3_03888 1239962.C943_01452 5.3e-93 347.1 Cytophagia ko:K09939 ko00000 Bacteria 47PX8@768503,4NIXJ@976,COG3182@1,COG3182@2 NA|NA|NA S PepSY-associated TM region MAG.T22.3_03889 531844.FIC_01221 1.3e-18 100.1 Flavobacteriia Bacteria 1I6QR@117743,2DRHR@1,33BTC@2,4NY0C@976 NA|NA|NA MAG.T22.3_03890 1239962.C943_01167 0.0 1526.1 Cytophagia hex 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 GH20 Bacteria 47JFD@768503,4NE08@976,COG3525@1,COG3525@2 NA|NA|NA G PFAM Glycoside hydrolase, family 20, catalytic core MAG.T22.3_03891 1239962.C943_01166 1.1e-157 563.9 Bacteroidetes 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 4PNNR@976,COG0457@1,COG0457@2,COG2114@1,COG2114@2 NA|NA|NA T Tetratricopeptide repeat MAG.T22.3_03892 388413.ALPR1_13625 4.1e-58 232.3 Cytophagia Bacteria 47MBD@768503,4NI53@976,COG1404@1,COG1404@2 NA|NA|NA O Peptidase S8 MAG.T22.3_03893 1239962.C943_01164 1.1e-206 725.7 Cytophagia Bacteria 47JVV@768503,4NDZF@976,COG4299@1,COG4299@2 NA|NA|NA S Protein of unknown function (DUF1624) MAG.T22.3_03894 1239962.C943_01163 2.5e-103 381.3 Cytophagia Bacteria 47NCP@768503,4NEPX@976,COG0727@1,COG0727@2 NA|NA|NA S Protein of unknown function (DUF3109) MAG.T22.3_03895 1239962.C943_01161 2e-211 741.5 Cytophagia ntrX Bacteria 47JKI@768503,4NE89@976,COG2204@1,COG2204@2 NA|NA|NA T CheY-like receiver AAA-type ATPase and DNA-binding domains MAG.T22.3_03897 1239962.C943_01159 6.5e-174 616.7 Cytophagia ko:K00666 ko00000,ko01000,ko01004 Bacteria 47JPB@768503,4NDXK@976,COG0318@1,COG0318@2 NA|NA|NA IQ PFAM Acyl-protein synthetase, LuxE MAG.T22.3_03898 1239962.C943_01158 8.7e-127 459.5 Cytophagia Bacteria 2E691@1,32WA1@2,47R10@768503,4NT8M@976 NA|NA|NA MAG.T22.3_03899 1239962.C943_01157 0.0 1540.8 Cytophagia pdhB 1.2.4.4,2.2.1.1 ko:K00615,ko:K11381 ko00030,ko00280,ko00640,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00280,map00640,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00036,M00165,M00167 R01067,R01641,R01830,R06590,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00032,RC00226,RC00571,RC00627,RC01560,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 47KBI@768503,4NE4A@976,COG0022@1,COG0022@2,COG1071@1,COG1071@2 NA|NA|NA C Dehydrogenase E1 component MAG.T22.3_03901 1239962.C943_01156 3.7e-207 727.2 Cytophagia ald 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 R00396 RC00008 ko00000,ko00001,ko01000 Bacteria 47K8G@768503,4NE8F@976,COG0686@1,COG0686@2 NA|NA|NA E Belongs to the AlaDH PNT family MAG.T22.3_03902 1239962.C943_01155 0.0 1139.0 Cytophagia capD 4.2.1.115,4.2.1.46 ko:K01710,ko:K15894 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 M00793 R06513,R09697 RC00402,RC02609 ko00000,ko00001,ko00002,ko01000 Bacteria 47KE5@768503,4NERY@976,COG1086@1,COG1086@2 NA|NA|NA GM Polysaccharide biosynthesis protein MAG.T22.3_03903 1239962.C943_01154 6.1e-87 327.0 Cytophagia pglC GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.36 ko:K15915,ko:K19428 R10184 RC00002 ko00000,ko01000 Bacteria 47PNC@768503,4NF29@976,COG2148@1,COG2148@2 NA|NA|NA M PFAM Bacterial sugar transferase MAG.T22.3_03904 1239962.C943_01153 3.2e-190 671.0 Cytophagia pglE 2.6.1.102,2.6.1.34 ko:K13010,ko:K15910,ko:K19430 ko00520,map00520 R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 Bacteria 47JTR@768503,4NFAI@976,COG0399@1,COG0399@2 NA|NA|NA E Belongs to the DegT DnrJ EryC1 family MAG.T22.3_03905 1239962.C943_01152 2.9e-202 711.1 Cytophagia wecA GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006629,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008963,GO:0009058,GO:0009059,GO:0009103,GO:0009246,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016051,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046378,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.8.33,2.7.8.35,5.1.3.14 ko:K01791,ko:K02851 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420,R08856 RC00002,RC00290 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 iAF987.Gmet_1505,iECSF_1327.ECSF_3624 Bacteria 47M4P@768503,4NGKM@976,COG0472@1,COG0472@2 NA|NA|NA M PFAM Glycosyl transferase family 4 MAG.T22.3_03906 1239962.C943_01151 8.5e-162 576.2 Cytophagia rfbA GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0334 Bacteria 47JPC@768503,4NE1U@976,COG1209@1,COG1209@2 NA|NA|NA M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis MAG.T22.3_03907 1239962.C943_01150 0.0 1114.8 Cytophagia Bacteria 29SIY@1,30DQ4@2,47TQK@768503,4NE5P@976 NA|NA|NA S Capsule assembly protein Wzi MAG.T22.3_03908 1239962.C943_01149 2.1e-211 741.5 Cytophagia ko:K00786 ko00000,ko01000 Bacteria 47XD2@768503,4NGU7@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase 4-like domain MAG.T22.3_03909 1239962.C943_01148 3.5e-275 953.7 Cytophagia Bacteria 47M3P@768503,4NHMA@976,COG5360@1,COG5360@2 NA|NA|NA S Heparinase II/III N-terminus MAG.T22.3_03910 1239962.C943_01147 1.2e-202 712.2 Cytophagia wecB 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 47M88@768503,4NGBD@976,COG0381@1,COG0381@2 NA|NA|NA M Belongs to the UDP-N-acetylglucosamine 2-epimerase family MAG.T22.3_03911 1239962.C943_01146 0.0 1300.0 Cytophagia Bacteria 47NZC@768503,4NFEW@976,COG0673@1,COG0673@2,COG1063@1,COG1063@2 NA|NA|NA E Zinc-binding dehydrogenase MAG.T22.3_03912 1239962.C943_01145 9.4e-133 479.6 Cytophagia hisF2 ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 47PCG@768503,4NM6U@976,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit MAG.T22.3_03913 1239962.C943_01144 1.6e-111 408.7 Cytophagia hisH ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 47QYQ@768503,4NF4J@976,COG0118@1,COG0118@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR MAG.T22.3_03914 1239962.C943_01143 3.4e-216 757.3 Cytophagia tilS 6.3.4.19 ko:K04075 R09597 RC02633,RC02634 ko00000,ko01000,ko03016 Bacteria 47PW8@768503,4NIZR@976,COG0037@1,COG0037@2 NA|NA|NA D LPS biosynthesis protein MAG.T22.3_03915 1239962.C943_01142 4.1e-225 786.9 Cytophagia Bacteria 47VZF@768503,4NWZH@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.3_03916 1239962.C943_01141 5.9e-58 230.7 Bacteria cat 2.3.1.28 ko:K00638,ko:K18234 br01600,ko00000,ko01000,ko01504 Bacteria COG0110@1,COG0110@2 NA|NA|NA S O-acyltransferase activity MAG.T22.3_03917 1239962.C943_01140 1e-204 719.2 Cytophagia Bacteria 2A6YP@1,30VTP@2,47WEP@768503,4PBW1@976 NA|NA|NA S EpsG family MAG.T22.3_03918 1239962.C943_01139 7.9e-168 596.3 Bacteria GO:0003674,GO:0003824,GO:0016740,GO:0016757 ko:K07011 ko00000 Bacteria COG1216@1,COG1216@2 NA|NA|NA V Glycosyl transferase, family 2 MAG.T22.3_03919 1239962.C943_01138 3.2e-254 884.0 Bacteria pglK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K19418 ko00000,ko02000 Bacteria COG2244@1,COG2244@2 NA|NA|NA S polysaccharide biosynthetic process MAG.T22.3_03920 1239962.C943_01137 5e-243 846.7 Cytophagia wbpO ko:K02474 ko00520,map00520 R06894 RC00291 ko00000,ko00001,ko01000,ko01005 Bacteria 47JKM@768503,4NDTW@976,COG0677@1,COG0677@2 NA|NA|NA M Belongs to the UDP-glucose GDP-mannose dehydrogenase family MAG.T22.3_03921 1239962.C943_01136 2.2e-254 884.4 Cytophagia ugd 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 Bacteria 47KAG@768503,4NE00@976,COG1004@1,COG1004@2 NA|NA|NA M Belongs to the UDP-glucose GDP-mannose dehydrogenase family MAG.T22.3_03923 1239962.C943_01135 4.4e-179 634.0 Cytophagia 3.1.21.3 ko:K01153,ko:K07011,ko:K16554 ko05111,map05111 ko00000,ko00001,ko01000,ko02000,ko02048 8.A.3.1 Bacteria 47NTB@768503,4NJJY@976,COG3206@1,COG3206@2 NA|NA|NA M PFAM Chain length determinant protein MAG.T22.3_03924 1239962.C943_01134 0.0 1617.8 Cytophagia kpsD ko:K01991 ko02026,map02026 ko00000,ko00001,ko02000 1.B.18 Bacteria 47K4B@768503,4NEXJ@976,COG1596@1,COG1596@2 NA|NA|NA M Polysaccharide biosynthesis export protein MAG.T22.3_03925 1239962.C943_01133 1e-78 299.3 Bacteroidetes Bacteria 4NS23@976,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional regulator MAG.T22.3_03926 1123057.P872_01435 1.1e-20 106.3 Cytophagia Bacteria 2EMN8@1,33FAJ@2,47T3F@768503,4NXKI@976 NA|NA|NA MAG.T22.3_03927 1239962.C943_01131 0.0 1370.1 Cytophagia quiP 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 Bacteria 47JRC@768503,4NEIX@976,COG2366@1,COG2366@2 NA|NA|NA S PFAM peptidase S45 penicillin amidase MAG.T22.3_03928 1239962.C943_01128 6e-100 370.2 Cytophagia Bacteria 47UHE@768503,4NTB3@976,COG0457@1,COG0457@2 NA|NA|NA S Protein of unknown function (DUF2911) MAG.T22.3_03929 1239962.C943_01126 2.7e-252 877.5 Cytophagia Bacteria 47JAU@768503,4NHVT@976,COG0006@1,COG0006@2 NA|NA|NA E Metallopeptidase family M24 MAG.T22.3_03930 1239962.C943_01124 7.7e-186 656.4 Cytophagia Bacteria 47P9B@768503,4NGUV@976,COG3568@1,COG3568@2 NA|NA|NA S Endonuclease/Exonuclease/phosphatase family MAG.T22.3_03931 1239962.C943_01123 0.0 1277.3 Cytophagia ko:K07003 ko00000 Bacteria 47JQA@768503,4NE0M@976,COG1033@1,COG1033@2 NA|NA|NA S COGs COG1033 exporter of the RND superfamily protein MAG.T22.3_03932 1239962.C943_01122 9.9e-154 549.3 Cytophagia thyA 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 Bacteria 47KE8@768503,4NEC2@976,COG0207@1,COG0207@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis MAG.T22.3_03933 1239962.C943_01121 1.3e-127 462.6 Cytophagia pabC 2.6.1.42,4.1.3.38 ko:K00826,ko:K02619 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R05553,R10991 RC00006,RC00036,RC01843,RC02148 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 47JMQ@768503,4NG0G@976,COG0115@1,COG0115@2 NA|NA|NA EH Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase MAG.T22.3_03934 1239962.C943_01120 7.4e-115 419.9 Cytophagia sdaAA 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 47NN2@768503,4NFXU@976,COG1760@1,COG1760@2 NA|NA|NA E Serine dehydratase MAG.T22.3_03935 1239962.C943_01119 8.9e-187 659.8 Cytophagia tolC ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 Bacteria 47M95@768503,4NEEN@976,COG1538@1,COG1538@2 NA|NA|NA MU PFAM Outer membrane efflux protein MAG.T22.3_03936 1239962.C943_01118 2e-212 745.0 Cytophagia macA ko:K02005 ko00000 Bacteria 47JF4@768503,4NFT4@976,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family MAG.T22.3_03937 1239962.C943_01117 1.1e-93 349.4 Cytophagia maf GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0022402,GO:0022607,GO:0030145,GO:0030312,GO:0030428,GO:0032506,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044085,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 1.1.1.25,2.1.1.190 ko:K00014,ko:K03215,ko:K06287 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 47JTY@768503,4NNXV@976,COG0424@1,COG0424@2 NA|NA|NA D Maf-like protein MAG.T22.3_03938 1239962.C943_01116 9.6e-239 832.4 Cytophagia Bacteria 47NI5@768503,4NGQH@976,COG4198@1,COG4198@2 NA|NA|NA S Protein of unknown function (DUF1015) MAG.T22.3_03939 1189612.A33Q_3068 2.2e-239 834.7 Cytophagia 6.3.4.14,6.4.1.2,6.4.1.3 ko:K01961,ko:K01965 ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00373,M00376,M00741 R00742,R01859,R04385 RC00040,RC00097,RC00253,RC00367,RC00609 ko00000,ko00001,ko00002,ko01000 Bacteria 47M7U@768503,4NM1W@976,COG4770@1,COG4770@2 NA|NA|NA I PFAM Carbamoyl-phosphate synthase L chain, ATP binding MAG.T22.3_03940 1239962.C943_01114 1.9e-228 798.1 Cytophagia kbl 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 47KDV@768503,4NFRY@976,COG0156@1,COG0156@2 NA|NA|NA E PFAM Aminotransferase class I and II MAG.T22.3_03941 1239962.C943_01113 5.2e-23 112.8 Cytophagia Bacteria 2BVK8@1,32Y0S@2,47RXH@768503,4NUUA@976 NA|NA|NA S Histone H1-like protein MAG.T22.3_03942 1239962.C943_01112 0.0 1234.6 Cytophagia 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 47JGQ@768503,4NEXH@976,COG0308@1,COG0308@2 NA|NA|NA E PFAM Peptidase M1, membrane alanine aminopeptidase MAG.T22.3_03943 1239962.C943_01111 1e-235 822.4 Cytophagia nfeD ko:K07403 ko00000 Bacteria 47MQR@768503,4NGGV@976,COG1030@1,COG1030@2 NA|NA|NA O Membrane-bound serine protease (ClpP class) MAG.T22.3_03944 1239962.C943_01110 2.4e-199 701.4 Cytophagia ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iIT341.HP0903m,iNJ661.Rv0409 Bacteria 47NZB@768503,4NFI0@976,COG0282@1,COG0282@2 NA|NA|NA C Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction MAG.T22.3_03945 1239962.C943_01109 4.4e-132 477.2 Bacteria XK27_07850 Bacteria COG0517@1,COG0517@2 NA|NA|NA S IMP dehydrogenase activity MAG.T22.3_03946 1239962.C943_01108 1.6e-257 894.8 Cytophagia 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 47XP7@768503,4NN5N@976,COG0793@1,COG0793@2 NA|NA|NA M Peptidase family S41 MAG.T22.3_03947 1189612.A33Q_2911 4.5e-51 207.2 Cytophagia Bacteria 2C85M@1,31482@2,47QCS@768503,4PQ28@976 NA|NA|NA S Stress responsive A/B Barrel Domain MAG.T22.3_03948 1239962.C943_01106 1.1e-178 632.5 Cytophagia tas Bacteria 47NMZ@768503,4NHA1@976,COG0667@1,COG0667@2 NA|NA|NA C aldo keto reductase MAG.T22.3_03949 1239962.C943_01105 1.6e-230 805.1 Cytophagia Bacteria 47P7K@768503,4NE6S@976,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.3_03950 1239962.C943_01104 3.7e-177 627.5 Cytophagia ntdA GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016740,GO:0016769,GO:0016999,GO:0017000,GO:0017144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.104 ko:K18653 R10698 RC00006,RC00781 ko00000,ko01000 Bacteria 47J92@768503,4NEBI@976,COG0399@1,COG0399@2 NA|NA|NA E Belongs to the DegT DnrJ EryC1 family MAG.T22.3_03951 1239962.C943_01103 6.6e-190 669.8 Cytophagia cyaD 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 47MSJ@768503,4NF1F@976,COG2114@1,COG2114@2,COG2204@1,COG2204@2 NA|NA|NA T Adenylyl cyclase class-3 4 guanylyl cyclase MAG.T22.3_03952 1239962.C943_01102 7.1e-62 243.0 Cytophagia ko:K03413 ko02020,ko02030,map02020,map02030 M00506 ko00000,ko00001,ko00002,ko02022,ko02035 Bacteria 47Y3Q@768503,4PMKE@976,COG2197@1,COG2197@2 NA|NA|NA KT cheY-homologous receiver domain MAG.T22.3_03953 1239962.C943_01100 0.0 1788.5 Cytophagia Bacteria 47N98@768503,4NEJX@976,COG3292@1,COG3292@2,COG4191@1,COG4191@2 NA|NA|NA T Y_Y_Y domain MAG.T22.3_03954 1239962.C943_01098 8.3e-136 490.7 Cytophagia Bacteria 47MSQ@768503,4NEJX@976,COG4191@1,COG4191@2 NA|NA|NA T Histidine kinase MAG.T22.3_03955 866536.Belba_0164 1e-213 749.2 Cytophagia Bacteria 47WDP@768503,4NRME@976,COG3328@1,COG3328@2 NA|NA|NA L PFAM Transposase, Mutator family MAG.T22.3_03956 1239962.C943_04606 3e-47 194.1 Cytophagia higA ko:K21498 ko00000,ko02048 Bacteria 47R1U@768503,4NSBZ@976,COG3093@1,COG3093@2 NA|NA|NA K TIGRFAM addiction module antidote protein, HigA family MAG.T22.3_03958 768710.DesyoDRAFT_3330 1e-08 67.0 Peptococcaceae Bacteria 1UPVD@1239,24NS7@186801,26638@186807,2DN8M@1,32W40@2 NA|NA|NA S YcxB-like protein MAG.T22.3_03959 1239962.C943_04604 1.6e-172 612.1 Cytophagia Bacteria 2ZA6T@2,47PN1@768503,4NGZ2@976,arCOG10456@1 NA|NA|NA MAG.T22.3_03960 1239962.C943_04602 5.4e-141 507.3 Bacteroidetes Bacteria 4NEMN@976,COG0451@1,COG0451@2 NA|NA|NA M NAD dependent epimerase dehydratase family MAG.T22.3_03961 1239962.C943_04601 9.2e-147 526.2 Cytophagia ko:K07124 ko00000 Bacteria 47PBG@768503,4NKNE@976,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T22.3_03962 1123248.KB893334_gene2753 6.2e-71 274.2 Bacteroidetes Bacteria 4NN9S@976,COG0596@1,COG0596@2 NA|NA|NA S Alpha/beta hydrolase family MAG.T22.3_03963 1239962.C943_04594 2e-53 214.9 Cytophagia Bacteria 47QIY@768503,4NQ4W@976,COG4898@1,COG4898@2 NA|NA|NA S protein conserved in bacteria MAG.T22.3_03965 1239962.C943_04593 0.0 1738.0 Cytophagia ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 iJN678.ppc Bacteria 47NYT@768503,4NFC0@976,COG2352@1,COG2352@2 NA|NA|NA C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle MAG.T22.3_03967 1239962.C943_04591 2.1e-165 588.2 Cytophagia Bacteria 2DBR4@1,2ZAI1@2,47UF4@768503,4NTEE@976 NA|NA|NA S Concanavalin A-like lectin/glucanases superfamily MAG.T22.3_03968 1239962.C943_04590 4e-180 637.5 Cytophagia afr Bacteria 47MIQ@768503,4NFY3@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain MAG.T22.3_03969 1239962.C943_04588 2.4e-108 398.3 Cytophagia 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria 47NE8@768503,4NMT2@976,COG2133@1,COG2133@2 NA|NA|NA G Domain of Unknown Function (DUF1080) MAG.T22.3_03970 1239962.C943_04586 1.2e-114 419.5 Cytophagia Bacteria 47Q29@768503,4NP0E@976,COG3279@1,COG3279@2 NA|NA|NA KT LytTr DNA-binding domain MAG.T22.3_03971 1239962.C943_04585 2.8e-111 407.9 Cytophagia Bacteria 2D9XB@1,32TU6@2,47R3J@768503,4NSXG@976 NA|NA|NA MAG.T22.3_03972 1239962.C943_04584 1.7e-191 675.2 Cytophagia 3.4.16.4 ko:K01286 ko00000,ko01000 Bacteria 47M8G@768503,4NER1@976,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T22.3_03973 1239962.C943_04583 1.8e-148 531.9 Bacteria Bacteria COG2120@1,COG2120@2 NA|NA|NA S N-acetylglucosaminylinositol deacetylase activity MAG.T22.3_03974 1239962.C943_04582 0.0 2057.0 Cytophagia Bacteria 47MFW@768503,4NH6B@976,COG1413@1,COG1413@2,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA C PFAM PBS lyase MAG.T22.3_03975 1239962.C943_04580 1.3e-185 655.6 Cytophagia 4.3.1.27 ko:K20757 ko00000,ko01000 Bacteria 47MJP@768503,4NF5K@976,COG3616@1,COG3616@2 NA|NA|NA E Putative serine dehydratase domain MAG.T22.3_03976 1239962.C943_04579 3e-278 963.8 Cytophagia lysA 4.1.1.19,4.1.1.20 ko:K01585,ko:K01586 ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map01100,map01110,map01120,map01130,map01230 M00016,M00133,M00525,M00526,M00527 R00451,R00566 RC00299 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS18870 Bacteria 47JRV@768503,4NFHV@976,COG0019@1,COG0019@2 NA|NA|NA E PFAM Pyridoxal-dependent decarboxylase, C-terminal sheet domain MAG.T22.3_03977 1123057.P872_08965 2e-24 119.0 Cytophagia Bacteria 2DN25@1,32V3H@2,47R7D@768503,4NTNA@976 NA|NA|NA MAG.T22.3_03978 1239962.C943_04577 6.6e-69 266.5 Cytophagia ko:K13643 ko00000,ko03000 Bacteria 47RMT@768503,4NNN2@976,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator MAG.T22.3_03979 1239962.C943_04576 7.6e-147 526.6 Cytophagia ytnM ko:K07090 ko00000 Bacteria 47K77@768503,4PKBI@976,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein MAG.T22.3_03980 1239962.C943_04575 0.0 1640.9 Cytophagia ko:K02014 ko00000,ko02000 1.B.14 Bacteria 47XWP@768503,4PKB8@976,COG4774@1,COG4774@2 NA|NA|NA P TonB dependent receptor MAG.T22.3_03981 1239962.C943_04574 0.0 1427.5 Cytophagia glgX 3.2.1.68 ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11261 ko00000,ko00001,ko00002,ko01000 CBM48,GH13 Bacteria 47KIY@768503,4NIH2@976,COG1523@1,COG1523@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family MAG.T22.3_03982 1239962.C943_04573 0.0 1853.2 Cytophagia addA 3.1.11.5,3.6.4.12 ko:K03582,ko:K16898 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 47KES@768503,4NEX4@976,COG1074@1,COG1074@2 NA|NA|NA L Belongs to the helicase family. UvrD subfamily MAG.T22.3_03983 1239962.C943_04572 1e-62 246.1 Bacteria ko:K15977 ko00000 Bacteria COG2259@1,COG2259@2 NA|NA|NA S methylamine metabolic process MAG.T22.3_03984 1239962.C943_04570 2.6e-76 292.0 Cytophagia Bacteria 47VFI@768503,4P4BJ@976,COG2931@1,COG2931@2 NA|NA|NA Q calcium- and calmodulin-responsive adenylate cyclase activity MAG.T22.3_03985 1239962.C943_02859 9e-42 176.4 Bacteroidetes Bacteria 2E00E@1,32VPV@2,4NSNA@976 NA|NA|NA MAG.T22.3_03986 1239962.C943_04568 2.9e-183 647.9 Cytophagia 1.14.15.3 ko:K00496,ko:K10616,ko:K15757 ko00071,ko00622,ko00623,ko00930,ko01100,ko01120,ko01220,map00071,map00622,map00623,map00930,map01100,map01120,map01220 M00419,M00537 R01347,R02281,R02550,R05266,R05288,R05442,R05443,R06945 RC00269,RC00478 ko00000,ko00001,ko00002,ko01000 Bacteria 47UEF@768503,4NIC2@976,COG3239@1,COG3239@2 NA|NA|NA I Fatty acid desaturase MAG.T22.3_03987 1239962.C943_04567 1.9e-89 335.1 Cytophagia btuE 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 Bacteria 47PPR@768503,4NM6G@976,COG0386@1,COG0386@2 NA|NA|NA O Belongs to the glutathione peroxidase family MAG.T22.3_03988 1239962.C943_04566 1.3e-193 682.2 Cytophagia cel 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 47JPS@768503,4NIW2@976,COG1363@1,COG1363@2 NA|NA|NA G PFAM M42 glutamyl aminopeptidase MAG.T22.3_03989 1239962.C943_04565 6.8e-54 216.5 Cytophagia Bacteria 47REC@768503,4NSHT@976,COG0745@1,COG0745@2 NA|NA|NA KT Response regulator receiver domain MAG.T22.3_03990 1239962.C943_04564 0.0 1241.9 Cytophagia purF 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 47JRN@768503,4NFSM@976,COG0034@1,COG0034@2 NA|NA|NA F PFAM Glutamine amidotransferase, class-II MAG.T22.3_03991 1123057.P872_02450 1.8e-13 82.0 Cytophagia Bacteria 2DTD9@1,33JU6@2,47T7U@768503,4NXWB@976 NA|NA|NA MAG.T22.3_03992 1239962.C943_04561 3.2e-243 847.4 Cytophagia ko:K07712,ko:K07713 ko02020,map02020 M00497,M00499 ko00000,ko00001,ko00002,ko02022 Bacteria 47N6B@768503,4NE89@976,COG2204@1,COG2204@2 NA|NA|NA T two component, sigma54 specific, transcriptional regulator, Fis family MAG.T22.3_03993 1239962.C943_04560 0.0 1435.6 Cytophagia Bacteria 47YGV@768503,4PKU4@976,COG0642@1,COG0642@2,COG0784@1,COG0784@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain MAG.T22.3_03994 1239962.C943_04559 4.5e-91 340.5 Cytophagia mcrA Bacteria 47MEF@768503,4NJ0T@976,COG1403@1,COG1403@2 NA|NA|NA L HNH endonuclease MAG.T22.3_03995 1239962.C943_04558 4.4e-77 293.9 Cytophagia smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 47PRC@768503,4NNJU@976,COG0691@1,COG0691@2 NA|NA|NA J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA MAG.T22.3_03996 1239962.C943_04557 8.5e-193 679.5 Cytophagia tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 47JX0@768503,4NE8E@976,COG0533@1,COG0533@2 NA|NA|NA O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction MAG.T22.3_03998 1239962.C943_04556 0.0 2835.1 Cytophagia Bacteria 47KQP@768503,4NF7F@976,COG2911@1,COG2911@2 NA|NA|NA S PFAM Family of MAG.T22.3_03999 1239962.C943_04555 4.9e-243 846.7 Cytophagia phr 4.1.99.3 ko:K01669 ko00000,ko01000,ko03400 Bacteria 47MVE@768503,4NEDW@976,COG0415@1,COG0415@2 NA|NA|NA L DNA photolyase MAG.T22.3_04000 1239962.C943_04554 1.5e-169 602.1 Cytophagia mutS2 ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 47MJZ@768503,4NNNV@976,COG1193@1,COG1193@2 NA|NA|NA L PFAM Smr MAG.T22.3_04001 1239962.C943_04553 9.4e-147 526.2 Cytophagia Bacteria 2EWXG@1,33Q8V@2,47U3D@768503,4P16S@976 NA|NA|NA MAG.T22.3_04002 1239962.C943_04552 5.8e-175 620.2 Cytophagia yneE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08994 ko00000,ko02000 1.A.46.2 Bacteria 47M3V@768503,4NGJ0@976,COG3781@1,COG3781@2 NA|NA|NA S Bestrophin, RFP-TM, chloride channel MAG.T22.3_04003 1239962.C943_04551 1.2e-94 352.4 Cytophagia Bacteria 47Y1W@768503,4PMDG@976,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family MAG.T22.3_04004 1239962.C943_04550 9.6e-107 392.9 Cytophagia hisI GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.5.4.25,3.6.1.31,5.3.1.16 ko:K01496,ko:K01497,ko:K01523,ko:K01814,ko:K11755 ko00340,ko00740,ko00790,ko01100,ko01110,ko01230,ko02024,map00340,map00740,map00790,map01100,map01110,map01230,map02024 M00026,M00125 R00425,R04035,R04037,R04640 RC00002,RC00293,RC00945,RC01055,RC02504 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iHN637.CLJU_RS05760,iSB619.SA_RS14110,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186 Bacteria 47KYT@768503,4NERE@976,COG0139@1,COG0139@2,COG0140@1,COG0140@2 NA|NA|NA E Belongs to the PRA-CH family MAG.T22.3_04005 1239962.C943_04549 1.4e-133 482.3 Cytophagia hisF GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 3.5.4.19,3.6.1.31 ko:K01663,ko:K02500,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04558 RC00002,RC00010,RC01055,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 iECO111_1330.ECO111_2749,iEcolC_1368.EcolC_1617,iHN637.CLJU_RS05755,iLJ478.TM1036,iSB619.SA_RS14115,iYL1228.KPN_02481 Bacteria 47K9T@768503,4NE16@976,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit MAG.T22.3_04006 1239962.C943_04548 2e-266 924.5 Cytophagia gdhA 1.4.1.3 ko:K00261 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47K4Z@768503,4NEBH@976,COG0334@1,COG0334@2 NA|NA|NA E Belongs to the Glu Leu Phe Val dehydrogenases family MAG.T22.3_04007 1239962.C943_04547 7.2e-179 633.3 Cytophagia Bacteria 47NA8@768503,4NGND@976,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase MAG.T22.3_04010 1239962.C943_04535 1.8e-119 435.3 Cytophagia lolD ko:K09810 ko02010,map02010 M00255 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 Bacteria 47KXC@768503,4NFCG@976,COG1136@1,COG1136@2 NA|NA|NA V Part of the ABC transporter complex LolCDE involved in the translocation of MAG.T22.3_04011 1239962.C943_04534 4.1e-226 790.4 Cytophagia lolC ko:K09808 ko02010,map02010 M00255 ko00000,ko00001,ko00002,ko02000 3.A.1.125 Bacteria 47MB4@768503,4NHBR@976,COG4591@1,COG4591@2 NA|NA|NA M COGs COG4591 ABC-type transport system involved in lipoprotein release permease component MAG.T22.3_04012 1239962.C943_04533 3e-185 654.4 Cytophagia ko:K02005 ko00000 Bacteria 47MHD@768503,4NITE@976,COG0845@1,COG0845@2 NA|NA|NA M Efflux transporter, RND family, MFP subunit MAG.T22.3_04013 1239962.C943_04532 5.8e-138 496.9 Cytophagia Bacteria 47XH2@768503,4PKGY@976,COG4221@1,COG4221@2 NA|NA|NA S KR domain MAG.T22.3_04014 1239962.C943_04531 3.7e-277 960.3 Cytophagia FbpA Bacteria 47M54@768503,4NGP5@976,COG1293@1,COG1293@2 NA|NA|NA K Fibronectin-binding protein A N-terminus (FbpA) MAG.T22.3_04015 1239962.C943_04530 1.2e-140 505.8 Cytophagia phnP 2.3.1.181,3.1.4.55 ko:K03801,ko:K06167 ko00440,ko00785,ko01100,map00440,map00785,map01100 R07766,R07769,R10205 RC00039,RC00296,RC00992,RC02867 ko00000,ko00001,ko01000 Bacteria 47JF0@768503,4NDWB@976,COG1235@1,COG1235@2 NA|NA|NA S of the beta-lactamase superfamily I MAG.T22.3_04016 1239962.C943_04529 2.9e-44 184.1 Cytophagia Bacteria 2E4YQ@1,32ZSH@2,47RX3@768503,4NVKX@976 NA|NA|NA MAG.T22.3_04017 1239962.C943_04528 3.8e-63 247.3 Cytophagia rcsC GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006970,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009268,GO:0009628,GO:0009927,GO:0009987,GO:0010447,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0033554,GO:0035556,GO:0036211,GO:0042710,GO:0043170,GO:0043412,GO:0044010,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051716,GO:0060089,GO:0065007,GO:0071214,GO:0071470,GO:0071704,GO:0071944,GO:0104004,GO:0140096,GO:1901564 2.7.13.3 ko:K07677,ko:K07679 ko02020,ko02026,ko05133,map02020,map02026,map05133 M00474,M00477 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 47Q9X@768503,4NQW4@976,COG0784@1,COG0784@2 NA|NA|NA T PFAM response regulator receiver MAG.T22.3_04018 1239962.C943_04527 1.3e-134 485.7 Cytophagia evgS GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009268,GO:0009628,GO:0009927,GO:0009987,GO:0010447,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K02486,ko:K07677,ko:K07679 ko02020,ko02026,ko05133,map02020,map02026,map05133 M00474,M00477 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 47TPE@768503,4P0W2@976,COG0745@1,COG0745@2,COG2198@1,COG2198@2 NA|NA|NA T Histidine Phosphotransfer domain MAG.T22.3_04019 1239962.C943_04526 1.2e-134 486.1 Cytophagia miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 47KKI@768503,4NEAE@976,COG0324@1,COG0324@2 NA|NA|NA J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) MAG.T22.3_04020 1123057.P872_01225 2.1e-13 82.0 Cytophagia Bacteria 2DCUU@1,2ZFEU@2,47WC7@768503,4P72G@976 NA|NA|NA MAG.T22.3_04021 1239962.C943_04524 5.8e-178 630.2 Cytophagia pfkA 2.7.1.11,2.7.1.90 ko:K00850,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Bacteria 47JHZ@768503,4NF8F@976,COG0205@1,COG0205@2 NA|NA|NA G Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis MAG.T22.3_04022 1239962.C943_04523 3.8e-57 227.3 Cytophagia ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 47RWZ@768503,4NQBK@976,COG0629@1,COG0629@2 NA|NA|NA L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism MAG.T22.3_04023 720554.Clocl_0373 4.1e-10 70.9 Ruminococcaceae ko:K02030,ko:K03832,ko:K14475 ko05143,map05143 M00236 ko00000,ko00001,ko00002,ko02000 2.C.1.1,3.A.1.3 Bacteria 1VGF2@1239,24UJK@186801,3WN94@541000,COG0810@1,COG0810@2,COG5513@1,COG5513@2 NA|NA|NA M Chagasin family peptidase inhibitor I42 MAG.T22.3_04024 1239962.C943_04519 4.2e-294 1016.5 Cytophagia Bacteria 47KU0@768503,4NF48@976,COG2939@1,COG2939@2 NA|NA|NA E Serine carboxypeptidase MAG.T22.3_04025 1239962.C943_04516 1.9e-65 255.0 Cytophagia hit ko:K02503 ko00000,ko04147 Bacteria 47Q95@768503,4NQ4X@976,COG0537@1,COG0537@2 NA|NA|NA FG HIT family hydrolase MAG.T22.3_04026 1239962.C943_04515 9e-78 296.2 Cytophagia greA ko:K03624 ko00000,ko03021 Bacteria 47P7N@768503,4NNH6@976,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides MAG.T22.3_04027 1239962.C943_04513 5.2e-154 550.4 Cytophagia serA 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 47K6J@768503,4NEMQ@976,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase MAG.T22.3_04028 1239962.C943_04512 5.9e-124 450.3 Cytophagia ygdQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 47MB3@768503,4NFFD@976,COG0861@1,COG0861@2 NA|NA|NA P PFAM Integral membrane protein TerC MAG.T22.3_04029 1239962.C943_04511 9e-167 592.8 Cytophagia ypfJ GO:0005575,GO:0005576 ko:K07054 ko00000 Bacteria 47KPT@768503,4NDTZ@976,COG2321@1,COG2321@2 NA|NA|NA S Putative neutral zinc metallopeptidase MAG.T22.3_04030 1239962.C943_04510 0.0 3282.7 Cytophagia Bacteria 47XWU@768503,4NDXU@976,COG0515@1,COG0515@2,COG0642@1,COG2114@1,COG2114@2,COG2205@2,COG3899@1,COG3899@2 NA|NA|NA T PhoQ Sensor MAG.T22.3_04031 1239962.C943_04509 9e-292 1008.8 Cytophagia 2.3.1.51,3.1.3.3 ko:K15781 ko00000,ko01000 Bacteria 47YMT@768503,4PPET@976,COG2937@1,COG2937@2 NA|NA|NA I Belongs to the GPAT DAPAT family MAG.T22.3_04032 1239962.C943_04508 2.5e-267 927.5 Cytophagia ko:K07223 ko00000 Bacteria 47VZZ@768503,4P6QA@976,COG2837@1,COG2837@2 NA|NA|NA P iron assimilation MAG.T22.3_04033 1239962.C943_04507 3.5e-201 707.6 Cytophagia Bacteria 2DBCN@1,2Z8EJ@2,47QZ8@768503,4NR8H@976 NA|NA|NA MAG.T22.3_04034 1239962.C943_04505 2.9e-51 208.0 Bacteroidetes ko:K04750 ko00000 Bacteria 4NQD7@976,COG2764@1,COG2764@2 NA|NA|NA S Glyoxalase bleomycin resistance protein dioxygenase MAG.T22.3_04035 1239962.C943_04504 7.2e-75 286.6 Cytophagia Bacteria 299YT@1,2ZX0H@2,47QB8@768503,4NP1B@976 NA|NA|NA S Protein of unknown function (DUF4199) MAG.T22.3_04036 1239962.C943_04503 1.2e-94 352.4 Cytophagia Bacteria 29KMP@1,2Z9ZF@2,47QGW@768503,4NKVK@976 NA|NA|NA S Domain of unknown function (DUF4287) MAG.T22.3_04037 1279009.ADICEAN_01751 9.9e-09 67.4 Bacteria Bacteria 2DEGI@1,2ZMXA@2 NA|NA|NA MAG.T22.3_04038 1239962.C943_04501 8.6e-277 959.1 Cytophagia Bacteria 47NWE@768503,4NH6T@976,COG2010@1,COG2010@2,COG2133@1,COG2133@2 NA|NA|NA CG Glucose / Sorbosone dehydrogenase MAG.T22.3_04039 1239962.C943_04499 4.5e-41 174.1 Bacteria ko:K02657 ko02020,ko02025,map02020,map02025 M00507 ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 Bacteria COG2199@1,COG3706@2 NA|NA|NA T diguanylate cyclase activity MAG.T22.3_04040 1239962.C943_04498 2.4e-69 268.5 Bacteroidetes MA20_44825 Bacteria 4NSGY@976,COG4319@1,COG4319@2 NA|NA|NA S Domain of unknown function (DUF4440) MAG.T22.3_04041 1239962.C943_04497 1.5e-74 285.4 Cytophagia Bacteria 47T5V@768503,4NPHR@976,COG3832@1,COG3832@2 NA|NA|NA S Activator of Hsp90 ATPase homolog 1-like protein MAG.T22.3_04042 1239962.C943_04495 1.1e-145 522.7 Cytophagia hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 iECSF_1327.ECSF_1909 Bacteria 47M8W@768503,4NDW8@976,COG0040@1,COG0040@2 NA|NA|NA E ATP phosphoribosyltransferase MAG.T22.3_04043 1239962.C943_04494 8.4e-211 739.6 Cytophagia hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 Bacteria 47JSY@768503,4NFPZ@976,COG0141@1,COG0141@2 NA|NA|NA E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine MAG.T22.3_04044 1239962.C943_04493 8.3e-180 636.3 Cytophagia hisC 1.1.1.23,2.6.1.9 ko:K00013,ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R01158,R01163,R03012,R03243 RC00006,RC00099,RC00242,RC00463,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 47N2S@768503,4NEDI@976,COG0079@1,COG0079@2 NA|NA|NA E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily MAG.T22.3_04045 1239962.C943_01676 2.1e-290 1004.2 Cytophagia glgB 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13 Bacteria 47NPV@768503,4NECZ@976,COG0296@1,COG0296@2 NA|NA|NA G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position MAG.T22.3_04046 1239962.C943_01675 1.6e-205 721.8 Cytophagia uxuA 4.2.1.8 ko:K01686 ko00040,ko01100,map00040,map01100 M00061 R05606 RC00543 ko00000,ko00001,ko00002,ko01000 Bacteria 47JUT@768503,4NFA5@976,COG1312@1,COG1312@2 NA|NA|NA G Catalyzes the dehydration of D-mannonate MAG.T22.3_04048 1239962.C943_01674 4.4e-125 454.1 Cytophagia Bacteria 47MT1@768503,4NG8R@976,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase MAG.T22.3_04049 1239962.C943_01673 7.5e-261 906.0 Cytophagia uxaC GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019585,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 5.3.1.12 ko:K01812 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0579,iSbBS512_1146.SbBS512_E3528 Bacteria 47KAP@768503,4NFHS@976,COG1904@1,COG1904@2 NA|NA|NA G Glucuronate isomerase MAG.T22.3_04050 1239962.C943_01672 6.3e-177 626.7 Cytophagia ko:K02529 ko00000,ko03000 Bacteria 47NXJ@768503,4NDW6@976,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor MAG.T22.3_04051 1239962.C943_01671 1.2e-115 422.5 Cytophagia sirR ko:K03709 ko00000,ko03000 Bacteria 47JSQ@768503,4NGUP@976,COG1321@1,COG1321@2 NA|NA|NA K Iron dependent repressor, metal binding and dimerisation domain MAG.T22.3_04052 1239962.C943_01669 4.3e-179 634.0 Cytophagia wblG Bacteria 47PDF@768503,4NMMT@976,COG0438@1,COG0438@2 NA|NA|NA M PFAM Glycosyl transferases group 1 MAG.T22.3_04053 1239962.C943_01668 1.3e-121 442.6 Cytophagia dapD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 iSbBS512_1146.SbBS512_E0158,iYO844.BSU14180 Bacteria 47KHY@768503,4NEWD@976,COG2171@1,COG2171@2 NA|NA|NA E Belongs to the transferase hexapeptide repeat family MAG.T22.3_04054 1239962.C943_01667 8.4e-105 386.3 Cytophagia Bacteria 47PCR@768503,4NN6J@976,COG0457@1,COG0457@2 NA|NA|NA S TPR repeat MAG.T22.3_04055 1189612.A33Q_1284 5.6e-66 257.7 Cytophagia ko:K05516 ko00000,ko03036,ko03110 Bacteria 47QV8@768503,4NQGK@976,COG0484@1,COG0484@2 NA|NA|NA O heat shock protein binding MAG.T22.3_04056 1239962.C943_01663 4.3e-65 254.2 Cytophagia Bacteria 2DBWT@1,2ZBJ6@2,47S0W@768503,4NP6N@976 NA|NA|NA MAG.T22.3_04057 1239962.C943_01662 1.1e-60 239.2 Cytophagia MA20_15755 Bacteria 47QTW@768503,4NQGZ@976,COG3743@1,COG3743@2 NA|NA|NA S Domain of unknown function (DUF4332) MAG.T22.3_04058 1239962.C943_01661 7e-281 972.6 Cytophagia yjgR ko:K06915 ko00000 Bacteria 47M2I@768503,4NF3P@976,COG0433@1,COG0433@2 NA|NA|NA S Bacterial protein of unknown function (DUF853) MAG.T22.3_04059 1239962.C943_01660 3.7e-224 783.9 Cytophagia yhiN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K07007 ko00000 Bacteria 47JD1@768503,4NFME@976,COG2081@1,COG2081@2 NA|NA|NA S TIGRFAM flavoprotein, HI0933 family MAG.T22.3_04060 1239962.C943_01659 4e-57 227.3 Bacteroidetes Bacteria 4P5K9@976,COG2198@1,COG2198@2 NA|NA|NA T Histidine kinase MAG.T22.3_04061 1239962.C943_01658 2.8e-177 627.9 Cytophagia gap GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 47KPU@768503,4NEMF@976,COG0057@1,COG0057@2 NA|NA|NA G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family MAG.T22.3_04064 517417.Cpar_2024 9.2e-26 125.6 Chlorobi Bacteria 1FF1N@1090,COG4704@1,COG4704@2 NA|NA|NA S Fibrobacter succinogenes major domain (Fib_succ_major) MAG.T22.3_04065 1239962.C943_01656 2.6e-248 864.4 Cytophagia sdcS GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0034220,GO:0044425,GO:0051179,GO:0051234,GO:0055085,GO:0098656 ko:K14445 ko00000,ko02000 2.A.47.1 Bacteria 47JJT@768503,4NFDK@976,COG0471@1,COG0471@2 NA|NA|NA P PFAM Sodium sulfate symporter transmembrane region MAG.T22.3_04066 1239962.C943_00427 1.5e-180 638.6 Cytophagia Bacteria 47YNC@768503,4PKX1@976,COG5337@1,COG5337@2 NA|NA|NA M CotH kinase protein MAG.T22.3_04067 1239962.C943_00430 1.8e-253 881.3 Cytophagia gbpD Bacteria 47NYM@768503,4PJN0@976,COG4099@1,COG4099@2 NA|NA|NA S Phospholipase/Carboxylesterase MAG.T22.3_04068 32057.KB217478_gene7375 1.5e-16 92.4 Nostocales ko:K07171 ko00000,ko01000,ko02048 Bacteria 1G84W@1117,1HSAX@1161,COG2337@1,COG2337@2 NA|NA|NA T PemK-like, MazF-like toxin of type II toxin-antitoxin system MAG.T22.3_04070 1239962.C943_00431 1.5e-278 964.9 Cytophagia ko:K13049 ko00000,ko01000,ko01002 Bacteria 47MC5@768503,4NEHJ@976,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain MAG.T22.3_04071 1239962.C943_00433 9e-289 998.8 Cytophagia cry2 4.1.99.3 ko:K01669 ko00000,ko01000,ko03400 Bacteria 47KG5@768503,4NH55@976,COG0415@1,COG0415@2 NA|NA|NA L PFAM FAD binding domain of DNA photolyase MAG.T22.3_04072 1239962.C943_00434 9.4e-46 189.1 Cytophagia Bacteria 47R1M@768503,4NSB9@976,COG2963@1,COG2963@2 NA|NA|NA L Protein of unknown function (DUF2805) MAG.T22.3_04073 1239962.C943_00435 2.3e-86 324.7 Cytophagia ko:K07071 ko00000 Bacteria 47QN0@768503,4NQJG@976,COG4276@1,COG4276@2 NA|NA|NA S SRPBCC domain-containing protein MAG.T22.3_04074 1239962.C943_00437 1.8e-164 585.1 Cytophagia ko:K01463 ko00000,ko01000 Bacteria 47TIE@768503,4NEDJ@976,COG2120@1,COG2120@2 NA|NA|NA S GlcNAc-PI de-N-acetylase MAG.T22.3_04075 1239962.C943_00438 1.8e-164 585.1 Cytophagia ko:K07214 ko00000 Bacteria 47KC9@768503,4PKKH@976,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold MAG.T22.3_04076 1239962.C943_00439 2.3e-209 734.6 Cytophagia Bacteria 47MJF@768503,4NFGY@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.3_04077 1239962.C943_00440 3.2e-136 491.1 Cytophagia Bacteria 47JG9@768503,4NGFR@976,COG1230@1,COG1230@2 NA|NA|NA P Co Zn Cd efflux system component MAG.T22.3_04078 1239962.C943_00441 0.0 1208.0 Cytophagia Bacteria 47KCN@768503,4NEMG@976,COG3507@1,COG3507@2 NA|NA|NA G PFAM coagulation factor 5 8 type MAG.T22.3_04079 1239962.C943_00442 1.4e-192 678.7 Cytophagia Bacteria 47MJ4@768503,4NHGI@976,COG2141@1,COG2141@2 NA|NA|NA C Luciferase-like monooxygenase MAG.T22.3_04080 1189612.A33Q_1482 3e-24 117.5 Cytophagia Bacteria 2DYZW@1,34BXP@2,47VNH@768503,4P66P@976 NA|NA|NA MAG.T22.3_04081 1123057.P872_12225 3.2e-121 441.4 Cytophagia Bacteria 47NJ6@768503,4NJ3Z@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase domain protein TIM barrel MAG.T22.3_04082 929562.Emtol_1648 3.2e-60 238.0 Cytophagia paiA GO:0003674,GO:0003824,GO:0004145,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0043937,GO:0043939,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0050793,GO:0051093,GO:0065007 2.3.1.57 ko:K22441 ko00000,ko01000 Bacteria 47Q73@768503,4NP1E@976,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain MAG.T22.3_04083 929562.Emtol_0593 1.1e-207 729.6 Cytophagia 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 Bacteria 47N7X@768503,4PMAQ@976,COG1231@1,COG1231@2 NA|NA|NA E Protein of unknown function (DUF1593) MAG.T22.3_04084 1239962.C943_00455 2.3e-247 861.3 Cytophagia 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 47JRY@768503,4NENR@976,COG1760@1,COG1760@2 NA|NA|NA E PFAM Serine dehydratase alpha chain MAG.T22.3_04085 1239962.C943_00456 4.6e-182 643.7 Cytophagia Bacteria 47N8N@768503,4NJN7@976,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase MAG.T22.3_04086 1239962.C943_00458 1.1e-173 615.9 Cytophagia ko:K09992 ko00000 Bacteria 47UFH@768503,4NEWH@976,COG3828@1,COG3828@2 NA|NA|NA S Methane oxygenase PmoA MAG.T22.3_04087 1239962.C943_00459 4.5e-263 913.3 Cytophagia Bacteria 47NH0@768503,4NGHJ@976,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.3_04088 1239962.C943_00460 8.5e-238 829.3 Cytophagia Bacteria 47MFM@768503,4NG5T@976,COG0673@1,COG0673@2 NA|NA|NA S Putative oxidoreductase C terminal domain MAG.T22.3_04089 1239962.C943_00461 0.0 1587.0 Cytophagia ko:K16091 ko00000,ko02000 1.B.14.1.14 Bacteria 47KFP@768503,4NH5V@976,COG4772@1,COG4772@2 NA|NA|NA P PFAM TonB-dependent Receptor MAG.T22.3_04090 1239962.C943_00463 6.9e-56 223.0 Cytophagia Bacteria 47RER@768503,4NQ98@976,COG0590@1,COG0590@2 NA|NA|NA FJ tRNA wobble adenosine to inosine editing MAG.T22.3_04091 643867.Ftrac_1969 2.6e-87 328.2 Cytophagia Bacteria 47PUV@768503,4NNKA@976,COG4185@1,COG4185@2 NA|NA|NA S Zeta toxin MAG.T22.3_04092 643867.Ftrac_1970 1.5e-15 88.2 Cytophagia Bacteria 2ACK8@1,32Q9N@2,47WAK@768503,4PBTD@976 NA|NA|NA MAG.T22.3_04094 1239962.C943_00465 6.5e-81 306.6 Cytophagia iorA3 1.3.99.16 ko:K07302,ko:K07303 ko00000,ko01000 Bacteria 47UKV@768503,4NM72@976,COG2080@1,COG2080@2 NA|NA|NA C [2Fe-2S] binding domain MAG.T22.3_04095 1239962.C943_00466 0.0 1510.4 Cytophagia iorB 1.3.99.16 ko:K07303 ko00000,ko01000 Bacteria 47N2K@768503,4NFFU@976,COG1529@1,COG1529@2 NA|NA|NA C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain MAG.T22.3_04096 1239962.C943_00467 0.0 1919.1 Cytophagia ko:K09800 ko00000,ko02000 Bacteria 47KTA@768503,4NHD3@976,COG2982@1,COG2982@2 NA|NA|NA M AsmA-like C-terminal region MAG.T22.3_04097 1239962.C943_00468 4.9e-163 580.5 Cytophagia ko:K09992 ko00000 Bacteria 47TDQ@768503,4NHIY@976,COG3828@1,COG3828@2 NA|NA|NA S Trehalose utilisation MAG.T22.3_04098 1123057.P872_22580 3.9e-79 302.4 Cytophagia Bacteria 47U5I@768503,4P0PS@976,COG3055@1,COG3055@2 NA|NA|NA S IPT/TIG domain MAG.T22.3_04099 1189612.A33Q_1562 6.4e-113 414.1 Cytophagia Bacteria 28I8D@1,2ZBHJ@2,47KUP@768503,4NHI9@976 NA|NA|NA S Domain of unknown function (DUF4249) MAG.T22.3_04100 1239962.C943_00470 6e-134 483.4 Cytophagia Bacteria 2CISN@1,2Z7MB@2,47MR9@768503,4NFJX@976 NA|NA|NA S Gluconate 2-dehydrogenase subunit 3 MAG.T22.3_04101 1239962.C943_00471 0.0 1194.9 Cytophagia Bacteria 47MZ9@768503,4NEHP@976,COG2303@1,COG2303@2 NA|NA|NA E Oxidoreductase MAG.T22.3_04102 1239962.C943_00472 5.7e-186 656.8 Cytophagia 3.2.1.21,3.4.11.1,3.6.3.34 ko:K01255,ko:K02013,ko:K05349 ko00460,ko00480,ko00500,ko00940,ko01100,ko01110,ko02010,map00460,map00480,map00500,map00940,map01100,map01110,map02010 M00240 R00026,R00899,R02558,R02887,R02985,R03527,R04949,R04951,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00096,RC00141,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000,ko01002,ko02000 3.A.1.14 GH3 Bacteria 47KI0@768503,4NG1Q@976,COG1120@1,COG1120@2 NA|NA|NA HP ABC transporter MAG.T22.3_04106 1239962.C943_00473 2.4e-184 651.4 Cytophagia btuC ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 47KF2@768503,4NEDU@976,COG0609@1,COG0609@2 NA|NA|NA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily MAG.T22.3_04107 1239962.C943_00474 1.1e-198 699.1 Cytophagia btuF ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 47MZX@768503,4NH9F@976,COG0614@1,COG0614@2 NA|NA|NA P PFAM periplasmic binding protein MAG.T22.3_04108 1239962.C943_00476 0.0 1234.2 Cytophagia btuB ko:K02014,ko:K16092 ko00000,ko02000 1.B.14,1.B.14.3 Bacteria 47M0G@768503,4NED9@976,COG4206@1,COG4206@2 NA|NA|NA H TonB-dependent Receptor Plug MAG.T22.3_04109 1239962.C943_00478 2.5e-157 561.6 Bacteria Bacteria COG3391@1,COG3391@2 NA|NA|NA CO amine dehydrogenase activity MAG.T22.3_04110 1239962.C943_00479 4.1e-226 790.4 Bacteria Bacteria COG3468@1,COG3468@2 NA|NA|NA MU cell adhesion MAG.T22.3_04111 1239962.C943_00480 4.8e-124 450.7 Cytophagia yusZ Bacteria 47NJG@768503,4NEKV@976,COG0300@1,COG0300@2 NA|NA|NA S KR domain MAG.T22.3_04112 1239962.C943_00481 1.6e-238 831.6 Cytophagia eno GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0009986,GO:0016829,GO:0016835,GO:0016836,GO:0019899,GO:0030312,GO:0035375,GO:0043236,GO:0044424,GO:0044464,GO:0044877,GO:0050840,GO:0071944 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 47MI4@768503,4NF5M@976,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis MAG.T22.3_04113 1239962.C943_00482 4.1e-190 670.6 Cytophagia carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383 Bacteria 47KT4@768503,4NEQI@976,COG0505@1,COG0505@2 NA|NA|NA F Belongs to the CarA family MAG.T22.3_04114 1239962.C943_00483 1.1e-78 299.3 Cytophagia rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 ko:K02879 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47PPE@768503,4NNW0@976,COG0203@1,COG0203@2 NA|NA|NA J Ribosomal protein L17 MAG.T22.3_04115 1239962.C943_00484 1e-179 636.0 Cytophagia rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 47JD5@768503,4NE8W@976,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates MAG.T22.3_04116 1239962.C943_00485 2.9e-105 387.9 Cytophagia rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47K3X@768503,4NEMZ@976,COG0522@1,COG0522@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit MAG.T22.3_04117 1239962.C943_00486 1.3e-66 258.8 Cytophagia rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47Q07@768503,4NNHA@976,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome MAG.T22.3_04118 1239962.C943_00487 6.1e-61 240.0 Cytophagia rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47PRH@768503,4NNGZ@976,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits MAG.T22.3_04119 1239962.C943_00488 1.8e-11 73.9 Bacteroidetes rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 4NXGE@976,COG0257@1,COG0257@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL36 family MAG.T22.3_04120 1123057.P872_23210 6.9e-33 146.0 Cytophagia infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 47RFD@768503,4NS6S@976,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex MAG.T22.3_04121 1239962.C943_00490 4.5e-143 513.8 Cytophagia map 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 47KDT@768503,4NERQ@976,COG0024@1,COG0024@2 NA|NA|NA E TIGRFAM methionine aminopeptidase, type I MAG.T22.3_04122 1239962.C943_00491 4.1e-237 827.0 Cytophagia secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 47JRD@768503,4NEPU@976,COG0201@1,COG0201@2 NA|NA|NA U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently MAG.T22.3_04123 866536.Belba_1728 7.3e-45 186.8 Cytophagia rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 ko:K02876 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47PP0@768503,4NNFQ@976,COG0200@1,COG0200@2 NA|NA|NA J Binds to the 23S rRNA MAG.T22.3_04124 1239962.C943_00493 1.8e-23 114.4 Cytophagia rpmD GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02907 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47S6M@768503,4NUXV@976,COG1841@1,COG1841@2 NA|NA|NA J Ribosomal protein L30 MAG.T22.3_04125 1239962.C943_00494 3.4e-86 324.3 Cytophagia rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02988 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47M7G@768503,4NG1Z@976,COG0098@1,COG0098@2 NA|NA|NA J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body MAG.T22.3_04126 1239962.C943_00495 2.7e-55 221.1 Cytophagia rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02881 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47RC9@768503,4NQAS@976,COG0256@1,COG0256@2 NA|NA|NA J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance MAG.T22.3_04127 1239962.C943_00496 8.6e-96 356.3 Cytophagia rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02933 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47PER@768503,4NGJM@976,COG0097@1,COG0097@2 NA|NA|NA J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center MAG.T22.3_04128 1189612.A33Q_0466 3.3e-65 254.2 Cytophagia rpsH GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904 ko:K02994 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47PPU@768503,4NNFW@976,COG0096@1,COG0096@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit MAG.T22.3_04129 1239962.C943_00498 2.9e-41 174.1 Cytophagia rpsN GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47QB0@768503,4NQ6N@976,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site MAG.T22.3_04130 1239962.C943_00499 1.5e-95 355.5 Cytophagia rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02931 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47KSN@768503,4NEGY@976,COG0094@1,COG0094@2 NA|NA|NA J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits MAG.T22.3_04131 1239962.C943_00500 1.4e-56 225.3 Cytophagia rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02895 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47R7A@768503,4NSTI@976,COG0198@1,COG0198@2 NA|NA|NA J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit MAG.T22.3_04132 1239962.C943_00501 3.6e-58 230.7 Cytophagia rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02874 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47PQH@768503,4NNM6@976,COG0093@1,COG0093@2 NA|NA|NA J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome MAG.T22.3_04133 1239962.C943_00502 2.3e-41 174.5 Cytophagia rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02961 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47R6N@768503,4NSB2@976,COG0186@1,COG0186@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA MAG.T22.3_04134 1239962.C943_00503 5.2e-24 116.3 Cytophagia rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02904 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47S5W@768503,4NUSC@976,COG0255@1,COG0255@2 NA|NA|NA J Belongs to the universal ribosomal protein uL29 family MAG.T22.3_04135 1123057.P872_23135 8.8e-69 266.2 Cytophagia rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02878 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47P74@768503,4NM87@976,COG0197@1,COG0197@2 NA|NA|NA J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs MAG.T22.3_04136 1239962.C943_00505 6.3e-134 483.4 Cytophagia rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02982 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47MFE@768503,4NE9F@976,COG0092@1,COG0092@2 NA|NA|NA J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation MAG.T22.3_04137 1288963.ADIS_4165 4.8e-53 213.8 Cytophagia rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47QFH@768503,4NQ8E@976,COG0091@1,COG0091@2 NA|NA|NA J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome MAG.T22.3_04138 1189612.A33Q_0476 1.2e-45 188.7 Cytophagia rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02965 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47QCA@768503,4NQ8T@976,COG0185@1,COG0185@2 NA|NA|NA J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA MAG.T22.3_04139 1239962.C943_00508 1.8e-150 538.5 Cytophagia rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02886 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47JS0@768503,4NE8G@976,COG0090@1,COG0090@2 NA|NA|NA J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity MAG.T22.3_04140 1239962.C943_00509 2.2e-39 167.9 Cytophagia rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02892 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47R4F@768503,4NS7H@976,COG0089@1,COG0089@2 NA|NA|NA J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome MAG.T22.3_04141 1239962.C943_00510 2.7e-106 391.3 Cytophagia rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02926,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47J8V@768503,4NEWZ@976,COG0088@1,COG0088@2 NA|NA|NA J Forms part of the polypeptide exit tunnel MAG.T22.3_04142 1239962.C943_00511 2.6e-126 458.0 Cytophagia rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 ko:K02906 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47KMY@768503,4NEAN@976,COG0087@1,COG0087@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit MAG.T22.3_04143 1239962.C943_00512 6.2e-48 196.4 Cytophagia rpsJ GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 ko:K02946 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47Q8W@768503,4NQ65@976,COG0051@1,COG0051@2 NA|NA|NA J Involved in the binding of tRNA to the ribosomes MAG.T22.3_04144 1239962.C943_00513 0.0 1404.4 Cytophagia fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02355 ko00000,ko03012,ko03029 Bacteria 47M8E@768503,4NE9X@976,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome MAG.T22.3_04145 1239962.C943_00514 1.3e-81 308.9 Cytophagia rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47P7P@768503,4NEEM@976,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA MAG.T22.3_04146 1166018.FAES_1239 7.2e-63 246.5 Cytophagia rpsL GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02950 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47PCE@768503,4NM3Y@976,COG0048@1,COG0048@2 NA|NA|NA J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit MAG.T22.3_04147 1239962.C943_00516 9.7e-55 219.2 Cytophagia 2.7.11.1,4.6.1.1 ko:K01768,ko:K12132 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko01001 Bacteria 47R37@768503,4NSNP@976,COG4191@1,COG4191@2 NA|NA|NA T Protein of unknown function (DUF3467) MAG.T22.3_04148 1189612.A33Q_0486 0.0 2642.8 Cytophagia rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 47JP0@768503,4NEMW@976,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates MAG.T22.3_04149 1239962.C943_00518 0.0 2520.3 Cytophagia rpoB GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03043,ko:K13797 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 47JXH@768503,4NF8D@976,COG0085@1,COG0085@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates MAG.T22.3_04150 1239962.C943_00519 1e-47 196.1 Cytophagia rplL ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47PSQ@768503,4NQAQ@976,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation MAG.T22.3_04151 1239962.C943_00520 2.3e-90 338.2 Cytophagia rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47JGP@768503,4NFFK@976,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors MAG.T22.3_04152 1239962.C943_00521 9.4e-124 449.5 Cytophagia rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47JJZ@768503,4NEIC@976,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release MAG.T22.3_04153 1239962.C943_00522 3.2e-77 294.3 Cytophagia rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47PEZ@768503,4NM60@976,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors MAG.T22.3_04154 866536.Belba_1697 2.1e-97 361.7 Cytophagia nusG GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 47KBF@768503,4NF2X@976,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination MAG.T22.3_04155 1239962.C943_00524 3.5e-25 120.2 Cytophagia secE GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 47RVC@768503,4NX53@976,COG0690@1,COG0690@2 NA|NA|NA U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation MAG.T22.3_04157 1239962.C943_00525 1.8e-223 781.6 Cytophagia tuf GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0016020,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 ko:K02358,ko:K15771 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 iSB619.SA_RS02960 Bacteria 47JYT@768503,4NEWS@976,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis MAG.T22.3_04161 1239962.C943_00527 0.0 1605.5 Cytophagia pepN 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 47KJ1@768503,4NFTN@976,COG0308@1,COG0308@2,COG1413@1,COG1413@2 NA|NA|NA CE Peptidase family M1 domain MAG.T22.3_04162 1239962.C943_00528 2e-59 235.3 Cytophagia pccA 6.4.1.3 ko:K01965,ko:K02160 ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00373,M00376,M00741 R00742,R01859 RC00040,RC00097,RC00367,RC00609 ko00000,ko00001,ko00002,ko01000 Bacteria 47QC5@768503,4NQ86@976,COG4770@1,COG4770@2 NA|NA|NA I Acetyl propionyl-CoA carboxylase alpha subunit MAG.T22.3_04163 1239962.C943_00529 9.2e-127 459.5 Cytophagia pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 47JC6@768503,4NE8Z@976,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP MAG.T22.3_04164 1239962.C943_00530 4e-93 347.4 Cytophagia frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 47P9Z@768503,4NF95@976,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another MAG.T22.3_04165 1239962.C943_00532 1.2e-114 419.1 Bacteria 1.5.1.40 ko:K06988 ko00000,ko01000 Bacteria COG2085@1,COG2085@2 NA|NA|NA S NADP oxidoreductase coenzyme F420-dependent MAG.T22.3_04166 1239962.C943_00533 4.6e-67 260.4 Cytophagia ctb ko:K06886 ko00000 Bacteria 47RTB@768503,4NQZD@976,COG2346@1,COG2346@2 NA|NA|NA S COG2346 Truncated hemoglobins MAG.T22.3_04167 1239962.C943_00534 1.1e-228 798.9 Bacteroidetes enpP 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 4NFFG@976,COG1524@1,COG1524@2 NA|NA|NA S type I phosphodiesterase nucleotide pyrophosphatase MAG.T22.3_04168 1239962.C943_00535 1.5e-205 721.8 Cytophagia aguA 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 R01416 RC00177 ko00000,ko00001,ko01000 Bacteria 47KQQ@768503,4NGF8@976,COG2957@1,COG2957@2 NA|NA|NA E Belongs to the agmatine deiminase family MAG.T22.3_04169 1239962.C943_00536 1.3e-162 578.9 Cytophagia aguB 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 R01152 RC00096 ko00000,ko00001,ko01000 Bacteria 47JFJ@768503,4NEME@976,COG0388@1,COG0388@2 NA|NA|NA S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase MAG.T22.3_04170 1239962.C943_00537 1.7e-132 478.8 Cytophagia catD 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 Bacteria 47NWA@768503,4NK80@976,COG2267@1,COG2267@2 NA|NA|NA I Ndr family MAG.T22.3_04171 1239962.C943_00538 0.0 1094.7 Cytophagia 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 Bacteria 47NDK@768503,4NG0U@976,COG1228@1,COG1228@2 NA|NA|NA Q Amidohydrolase family MAG.T22.3_04172 880070.Cycma_3211 1e-27 129.8 Cytophagia Bacteria 2A8KM@1,30XP0@2,47VA5@768503,4PB5K@976 NA|NA|NA MAG.T22.3_04173 1123057.P872_00335 0.0 1261.9 Cytophagia MA20_43810 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 47MB7@768503,4NF16@976,COG3127@1,COG3127@2 NA|NA|NA Q FtsX-like permease family MAG.T22.3_04174 1239962.C943_00541 1e-119 436.0 Cytophagia ybbA GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 47JSN@768503,4NEVZ@976,COG4181@1,COG4181@2 NA|NA|NA Q ABC transporter MAG.T22.3_04175 1239962.C943_00545 1.5e-102 379.0 Cytophagia tesA GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 ko:K10804 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 iECED1_1282.ECED1_0521,iLF82_1304.LF82_2242,iNRG857_1313.NRG857_02365 Bacteria 47P77@768503,4NE58@976,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase family MAG.T22.3_04176 102129.Lepto7375DRAFT_8142 6.8e-20 103.6 Oscillatoriales Bacteria 1G523@1117,1HC3W@1150,COG1569@1,COG1569@2 NA|NA|NA S PIN domain MAG.T22.3_04177 929556.Solca_2142 1.6e-23 115.9 Bacteroidetes Bacteria 4NUE2@976,COG3311@1,COG3311@2 NA|NA|NA K Helix-turn-helix domain MAG.T22.3_04178 1239962.C943_00546 0.0 1158.3 Cytophagia 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 47JTA@768503,4NFJP@976,COG0726@1,COG0726@2 NA|NA|NA G Glycosyl hydrolase family 9 MAG.T22.3_04179 1454007.JAUG01000058_gene3490 9.6e-23 112.8 Sphingobacteriia Bacteria 1IYC5@117747,4NVD2@976,COG4634@1,COG4634@2 NA|NA|NA MAG.T22.3_04180 1279009.ADICEAN_03701 2.6e-17 94.4 Cytophagia Bacteria 47S77@768503,4NV5I@976,COG2442@1,COG2442@2 NA|NA|NA S Protein of unknown function (DUF433) MAG.T22.3_04181 1239962.C943_00548 8.1e-238 829.3 Cytophagia Bacteria 47M6K@768503,4NGZR@976,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase class C and other penicillin binding MAG.T22.3_04182 1239962.C943_00549 0.0 1508.4 Cytophagia Bacteria 47JGS@768503,4NEIG@976,COG1629@1,COG4771@2 NA|NA|NA P TonB-dependent Receptor Plug MAG.T22.3_04183 1239962.C943_00550 2.9e-69 267.7 Cytophagia Bacteria 47R31@768503,4NSM6@976,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain MAG.T22.3_04184 1239962.C943_00551 5.4e-140 503.8 Cytophagia 5.1.3.30,5.1.3.31 ko:K18910 R10817,R10818 RC03111,RC03283 ko00000,ko01000 Bacteria 47PXI@768503,4NM4N@976,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T22.3_04185 1239962.C943_00552 5.6e-122 443.7 Cytophagia madM Bacteria 28HGK@1,2Z7SE@2,47N9G@768503,4NGDR@976 NA|NA|NA S Malonate/sodium symporter MadM subunit MAG.T22.3_04186 1239962.C943_00553 1.9e-56 224.9 Cytophagia madL Bacteria 2CAQ0@1,32RRS@2,47QP4@768503,4NRRH@976 NA|NA|NA S Malonate transporter MadL subunit MAG.T22.3_04187 1239962.C943_00554 7e-262 909.4 Cytophagia fadD36 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 ko:K12429,ko:K18660,ko:K18661,ko:K18662 ko00280,map00280 R03383 RC00004,RC00137 ko00000,ko00001,ko01000,ko01004 Bacteria 47NTH@768503,4NFPF@976,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme C-terminal domain MAG.T22.3_04188 1239962.C943_00555 1.4e-54 218.8 Bacteria Bacteria COG3682@1,COG3682@2 NA|NA|NA K negative regulation of transcription, DNA-templated MAG.T22.3_04189 1239962.C943_00556 2.9e-222 777.7 Cytophagia Bacteria 47YB7@768503,4NW2E@976,COG0810@1,COG0810@2 NA|NA|NA M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins MAG.T22.3_04190 1239962.C943_00557 5.5e-66 256.9 Cytophagia Bacteria 47KAX@768503,4NMG7@976,COG0810@1,COG0810@2 NA|NA|NA U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins MAG.T22.3_04191 1239962.C943_00558 0.0 1260.7 Cytophagia ams 2.4.1.4,3.2.1.1,5.4.99.16 ko:K05341,ko:K05343 ko00500,ko01100,map00500,map01100 R01557,R01823,R02108,R02112,R11262 RC00028,RC01816 ko00000,ko00001,ko01000 GH13 Bacteria 47XJK@768503,4NI8U@976,COG0366@1,COG0366@2 NA|NA|NA G Glycogen debranching enzyme, glucanotransferase domain MAG.T22.3_04192 1239962.C943_00559 3.4e-272 943.7 Cytophagia suc1 ko:K16211 ko00000,ko02000 2.A.2.6 Bacteria 47KS1@768503,4NE3F@976,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator MAG.T22.3_04193 1239962.C943_00561 3.1e-208 731.1 Cytophagia 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 GH33 Bacteria 47JRH@768503,4NFNK@976,COG4409@1,COG4409@2 NA|NA|NA G BNR repeat-like domain MAG.T22.3_04194 1239962.C943_00563 1e-200 706.1 Cytophagia citM ko:K03300 ko00000 2.A.11 Bacteria 47MP2@768503,4NHKQ@976,COG2851@1,COG2851@2 NA|NA|NA C Na+/H+ antiporter family MAG.T22.3_04195 1239962.C943_00564 2e-223 781.6 Cytophagia Bacteria 47N1N@768503,4NGFD@976,COG3185@1,COG3185@2 NA|NA|NA E Pfam:DUF1446 MAG.T22.3_04196 1239962.C943_00565 1.9e-47 194.9 Cytophagia Bacteria 2CIU6@1,32S8H@2,47R9I@768503,4NSPK@976 NA|NA|NA MAG.T22.3_04197 1239962.C943_00566 1.2e-115 422.5 Cytophagia nagB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016853,GO:0016860,GO:0016861,GO:0043877,GO:0044424,GO:0044444,GO:0044464 3.1.1.31,3.5.99.6 ko:K01057,ko:K02080,ko:K02564 ko00030,ko00052,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00052,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035,R08365 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 iB21_1397.B21_02959,iECB_1328.ECB_03008,iECD_1391.ECD_03008,iECNA114_1301.ECNA114_3225,iECSF_1327.ECSF_2979 Bacteria 47NRI@768503,4NPBJ@976,COG0363@1,COG0363@2 NA|NA|NA G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase MAG.T22.3_04198 1123057.P872_21000 4e-46 191.8 Cytophagia Bacteria 2F557@1,33XS8@2,47V1V@768503,4P3M3@976 NA|NA|NA MAG.T22.3_04199 1239962.C943_00568 3.5e-124 451.1 Cytophagia Bacteria 47QJS@768503,4NHBI@976,COG0474@1,COG0474@2 NA|NA|NA P ATPase, P-type transporting, HAD superfamily, subfamily IC MAG.T22.3_04200 1239962.C943_00569 7.4e-261 906.0 Cytophagia lpdA GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009507,GO:0009536,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0035639,GO:0036094,GO:0036211,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045271,GO:0046390,GO:0046483,GO:0046496,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0070469,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0106077,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 iE2348C_1286.E2348C_4372,iJN746.PP_4187 Bacteria 47K0E@768503,4NDVC@976,COG1249@1,COG1249@2 NA|NA|NA C Dihydrolipoyl dehydrogenase MAG.T22.3_04201 1239962.C943_00570 6.5e-271 939.5 Cytophagia sucB GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2766,iAPECO1_1312.APECO1_1352,iECED1_1282.ECED1_0696,iECOK1_1307.ECOK1_0726,iECS88_1305.ECS88_0752,iLF82_1304.LF82_2196,iNRG857_1313.NRG857_03235,iUMN146_1321.UM146_13990,iUTI89_1310.UTI89_C0722 Bacteria 47K2Z@768503,4NF33@976,COG0508@1,COG0508@2 NA|NA|NA C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) MAG.T22.3_04202 1239962.C943_00571 0.0 1845.1 Cytophagia sucA GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 ko:K00164,ko:K01616 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1248c,iSSON_1240.SSON_0677,iYL1228.KPN_00732 Bacteria 47JXI@768503,4NEU9@976,COG0567@1,COG0567@2 NA|NA|NA C 2-oxoglutarate dehydrogenase, E1 MAG.T22.3_04203 1239962.C943_00572 2.1e-137 495.4 Cytophagia Bacteria 2AM3F@1,31BXJ@2,47PK8@768503,4NPAN@976 NA|NA|NA MAG.T22.3_04204 1239962.C943_00573 0.0 1075.5 Cytophagia Bacteria 47M7F@768503,4NFT1@976,COG0521@1,COG0521@2 NA|NA|NA H Starch-binding associating with outer membrane MAG.T22.3_04205 1239962.C943_00574 0.0 2096.6 Cytophagia Bacteria 47K6G@768503,4NDU8@976,COG1629@1,COG1629@2,COG4771@2 NA|NA|NA P PFAM TonB-dependent Receptor Plug MAG.T22.3_04207 1239962.C943_00577 2.6e-88 331.3 Bacteria Bacteria 2DM4T@1,31QCU@2 NA|NA|NA MAG.T22.3_04208 1239962.C943_00578 2.1e-97 361.7 Cytophagia ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 Bacteria 47Q5G@768503,4NM97@976,COG0212@1,COG0212@2 NA|NA|NA H 5-formyltetrahydrofolate cyclo-ligase family MAG.T22.3_04209 1239962.C943_00579 1.7e-285 988.0 Cytophagia bshC ko:K22136 ko00000 Bacteria 47JYH@768503,4NGCF@976,COG4365@1,COG4365@2 NA|NA|NA S Belongs to the BshC family MAG.T22.3_04210 1239962.C943_00580 0.0 1300.8 Cytophagia 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 47MMN@768503,4NERS@976,COG2217@1,COG2217@2 NA|NA|NA P ATPase, P-type (transporting), HAD superfamily, subfamily IC MAG.T22.3_04211 1239962.C943_00581 5.7e-29 132.9 Bacteria merP ko:K07213,ko:K08364 ko04978,map04978 ko00000,ko00001,ko02000 1.A.72.1 Bacteria COG2608@1,COG2608@2 NA|NA|NA P mercury ion transmembrane transporter activity MAG.T22.3_04212 1239962.C943_00582 1.3e-232 812.0 Cytophagia ko:K07263 ko00000,ko01000,ko01002 Bacteria 47JGY@768503,4NEDZ@976,COG0612@1,COG0612@2 NA|NA|NA S PFAM Peptidase M16 inactive domain MAG.T22.3_04213 1239962.C943_00583 2.6e-88 331.3 Cytophagia ispF GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008270,GO:0008685,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016849,GO:0030145,GO:0042180,GO:0042181,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.228,2.7.7.60,4.6.1.12 ko:K00554,ko:K00991,ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05633,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 iPC815.YPO3360 Bacteria 47PDR@768503,4NP0N@976,COG0245@1,COG0245@2 NA|NA|NA I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) MAG.T22.3_04214 1239962.C943_00584 1.4e-127 462.2 Cytophagia mnmC 2.1.1.61,2.4.2.29,4.2.1.151 ko:K00773,ko:K11782,ko:K15461 ko00130,ko01110,map00130,map01110 R00601,R03789,R08702,R10209,R10666 RC00003,RC00053,RC00060,RC00063,RC01483,RC03232 ko00000,ko00001,ko01000,ko03016 Bacteria 47QBX@768503,4NE5S@976,COG4121@1,COG4121@2 NA|NA|NA S S-adenosyl-L-methionine-dependent methyltransferase MAG.T22.3_04215 1239962.C943_00585 0.0 2640.5 Cytophagia Bacteria 28MEF@1,2ZAS2@2,47P38@768503,4NKXT@976 NA|NA|NA MAG.T22.3_04216 1239962.C943_00587 5.1e-198 696.8 Cytophagia rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 47MPT@768503,4NEV3@976,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil MAG.T22.3_04217 1239962.C943_00588 3.1e-138 498.0 Cytophagia acdS 3.5.99.7,4.4.1.15 ko:K01505,ko:K05396 ko00270,map00270 R00997,R01874 RC00382,RC00419 ko00000,ko00001,ko01000 Bacteria 47JNZ@768503,4NEP9@976,COG2515@1,COG2515@2 NA|NA|NA E 1-aminocyclopropane-1-carboxylate deaminase MAG.T22.3_04218 1239962.C943_00589 1.9e-99 368.6 Cytophagia Bacteria 47N5X@768503,4NGPG@976,COG2865@1,COG2865@2 NA|NA|NA K transcriptional regulator MAG.T22.3_04219 1239962.C943_00590 0.0 1303.1 Cytophagia uvrB GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 47KBV@768503,4NE6E@976,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage MAG.T22.3_04220 1239962.C943_00591 4.5e-219 766.9 Cytophagia Bacteria 28I3N@1,2Z87C@2,47M50@768503,4NE8P@976 NA|NA|NA S Domain of unknown function (DUF4105) MAG.T22.3_04221 1239962.C943_00592 0.0 1303.9 Cytophagia Bacteria 47TUZ@768503,4P11A@976,COG3391@1,COG3391@2 NA|NA|NA S amine dehydrogenase activity MAG.T22.3_04222 1239962.C943_00594 6.8e-224 783.1 Cytophagia gntT GO:0003674,GO:0005215,GO:0005342,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008028,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015128,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015568,GO:0015672,GO:0015711,GO:0015718,GO:0015726,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0035429,GO:0042873,GO:0042879,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1902600,GO:1903825,GO:1905039 ko:K03299,ko:K06155,ko:K06157,ko:K16321 ko00000,ko02000 2.A.8,2.A.8.1.2,2.A.8.1.3,2.A.8.1.4 iHN637.CLJU_RS05690,iHN637.CLJU_RS13905,iSSON_1240.SSON_3547 Bacteria 47KJN@768503,4NFBD@976,COG2610@1,COG2610@2 NA|NA|NA EG TIGRFAM gluconate transporter MAG.T22.3_04223 1239962.C943_00595 2.7e-82 311.2 Cytophagia Bacteria 47P6V@768503,4NMAM@976,COG0251@1,COG0251@2 NA|NA|NA J PFAM Endoribonuclease L-PSP MAG.T22.3_04228 1492737.FEM08_16590 2.7e-27 130.6 Flavobacterium ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1I5TZ@117743,2NWF8@237,4NK87@976,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin-like MAG.T22.3_04229 1239962.C943_00596 1.4e-206 725.3 Cytophagia 3.4.13.19 ko:K01273 ko00000,ko00537,ko01000,ko01002,ko04147 Bacteria 47JHU@768503,4NDYZ@976,COG2355@1,COG2355@2 NA|NA|NA E PFAM Peptidase M19, renal dipeptidase MAG.T22.3_04230 1239962.C943_00597 8.7e-178 629.4 Bacteria 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria COG0327@1,COG0327@2 NA|NA|NA L Belongs to the GTP cyclohydrolase I type 2 NIF3 family MAG.T22.3_04231 1239962.C943_00598 1.6e-103 382.1 Cytophagia cysG 1.3.1.76,4.99.1.4 ko:K02304,ko:K07090 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03947 RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 Bacteria 47PPT@768503,4NI81@976,COG1648@1,COG1648@2 NA|NA|NA H Siroheme synthase MAG.T22.3_04232 1239962.C943_00599 8.2e-140 503.1 Cytophagia cobA 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 ko:K02302,ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03165,R03194,R03947 RC00003,RC00871,RC01012,RC01034,RC01861 ko00000,ko00001,ko00002,ko01000 Bacteria 47JQG@768503,4NFVR@976,COG0007@1,COG0007@2 NA|NA|NA H TIGRFAM Uroporphyrin-III C-methyltransferase MAG.T22.3_04233 1239962.C943_00600 0.0 1353.6 Cytophagia cysI 1.7.1.15,1.7.7.1,1.8.1.2,1.8.7.1 ko:K00362,ko:K00366,ko:K00381,ko:K00392 ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120 M00176,M00530,M00531 R00787,R00790,R00858,R00859,R03600 RC00065,RC00176 ko00000,ko00001,ko00002,ko01000 Bacteria 47MYH@768503,4NENW@976,COG0155@1,COG0155@2 NA|NA|NA C Nitrite and sulphite reductase 4Fe-4S MAG.T22.3_04234 1239962.C943_00601 2e-233 814.7 Cytophagia cysN GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 47KGK@768503,4NETI@976,COG2895@1,COG2895@2 NA|NA|NA P Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily MAG.T22.3_04235 1239962.C943_00602 1e-167 595.9 Cytophagia cysD GO:0000103,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:1902494,GO:1902503,GO:1990234 1.8.4.10,1.8.4.8,2.7.7.4 ko:K00390,ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R02021,R04929 RC00007,RC02809,RC02862,RC02889 ko00000,ko00001,ko00002,ko01000 Bacteria 47JCC@768503,4NEPD@976,COG0175@1,COG0175@2 NA|NA|NA EH TIGRFAM sulfate adenylyltransferase, small subunit MAG.T22.3_04236 1239962.C943_00603 2.1e-131 474.9 Cytophagia cysH GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.7.7.1,1.8.4.10,1.8.4.8,2.7.1.25 ko:K00366,ko:K00390,ko:K00860 ko00230,ko00910,ko00920,ko01100,ko01120,map00230,map00910,map00920,map01100,map01120 M00176,M00531 R00509,R00790,R02021,R04928 RC00002,RC00007,RC00078,RC00176,RC02862 ko00000,ko00001,ko00002,ko01000 Bacteria 47KPR@768503,4NGVI@976,COG0175@1,COG0175@2 NA|NA|NA EH Reduction of activated sulfate into sulfite MAG.T22.3_04237 1239962.C943_00604 8.2e-73 280.0 Cytophagia ko:K13643 ko00000,ko03000 Bacteria 47P88@768503,4NNN2@976,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator MAG.T22.3_04239 1239962.C943_00608 8.5e-142 509.6 Bacteria Bacteria COG2197@1,COG2197@2 NA|NA|NA K response regulator MAG.T22.3_04240 1305737.JAFX01000001_gene3332 1.5e-40 173.7 Bacteroidetes Bacteria 4PMVS@976,COG3391@1,COG3391@2 NA|NA|NA S TolB-like 6-blade propeller-like MAG.T22.3_04243 1239962.C943_00609 0.0 1230.7 Cytophagia htpG GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071450,GO:0071451,GO:0071944,GO:1901700,GO:1901701 ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Bacteria 47JAZ@768503,4NDXZ@976,COG0326@1,COG0326@2 NA|NA|NA O Molecular chaperone. Has ATPase activity MAG.T22.3_04244 1239962.C943_00613 1.6e-72 279.6 Cytophagia 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000 Bacteria 47UYD@768503,4NNM5@976,COG0223@1,COG0223@2 NA|NA|NA J Formyl transferase MAG.T22.3_04245 1239962.C943_00614 1.9e-110 405.2 Cytophagia ccmB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 ko:K02193,ko:K02194 ko02010,map02010 M00259 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 iECO111_1330.ECO111_2936,iYL1228.KPN_02080 Bacteria 47K0P@768503,4NFQV@976,COG2386@1,COG2386@2 NA|NA|NA O ABC-type transport system involved in cytochrome c biogenesis permease component MAG.T22.3_04246 1239962.C943_00615 2.9e-122 444.5 Cytophagia ccmC GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 ko:K02195 ko02010,map02010 M00259 ko00000,ko00001,ko00002,ko02000 3.A.1.107 iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736 Bacteria 47MYQ@768503,4NFUS@976,COG0755@1,COG0755@2 NA|NA|NA O PFAM Cytochrome c assembly protein MAG.T22.3_04247 1239962.C943_00616 2.4e-34 151.0 Cytophagia Bacteria 2BZQ6@1,339SI@2,47SN2@768503,4NXJG@976 NA|NA|NA MAG.T22.3_04248 1239962.C943_00617 7.9e-70 269.6 Cytophagia ccmE ko:K02197 ko00000 Bacteria 47PIE@768503,4NN85@976,COG2332@1,COG2332@2 NA|NA|NA O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH MAG.T22.3_04249 1239962.C943_00618 0.0 1632.5 Cytophagia ccmF ko:K02198 ko00000,ko02000 9.B.14.1 Bacteria 47M2N@768503,4NGXI@976,COG1138@1,COG1138@2 NA|NA|NA O PFAM Cytochrome c assembly protein MAG.T22.3_04250 1239962.C943_00620 2.9e-229 800.8 Cytophagia pepR GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 47JFQ@768503,4NEE4@976,COG0612@1,COG0612@2 NA|NA|NA S PFAM Peptidase M16 inactive domain MAG.T22.3_04251 1239962.C943_00621 1.5e-112 412.1 Cytophagia yrrM 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 Bacteria 47KAK@768503,4NH42@976,COG4122@1,COG4122@2 NA|NA|NA S PFAM O-methyltransferase MAG.T22.3_04252 1239962.C943_00622 1.5e-286 991.5 Cytophagia mltD ko:K08307,ko:K12204,ko:K16291 ko00000,ko01000,ko01002,ko01011,ko02044 3.A.7.10.1,3.A.7.9.1 Bacteria 47V3U@768503,4P3V1@976,COG0741@1,COG0741@2,COG1388@1,COG1388@2 NA|NA|NA M Transglycosylase SLT domain MAG.T22.3_04253 1239962.C943_00623 4e-160 570.9 Cytophagia ydiY ko:K07283 ko00000 Bacteria 47Q2F@768503,4NGB2@976,COG3137@1,COG3137@2 NA|NA|NA M Protein of unknown function (DUF3078) MAG.T22.3_04254 1048983.EL17_06410 2e-23 115.5 Cytophagia 3.6.4.13,5.4.99.21 ko:K03578,ko:K06182 ko00000,ko01000,ko03009 Bacteria 47SUJ@768503,4PNNG@976,COG3170@1,COG3170@2 NA|NA|NA NU Tfp pilus assembly protein FimV MAG.T22.3_04255 1239962.C943_00626 3.6e-213 747.3 Cytophagia dnaX 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 47KSQ@768503,4NE8A@976,COG2812@1,COG2812@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity MAG.T22.3_04256 1239962.C943_00628 1.8e-136 491.9 Cytophagia Bacteria 47MAX@768503,4NI4M@976,COG5495@1,COG5495@2 NA|NA|NA S NADP oxidoreductase coenzyme F420-dependent MAG.T22.3_04258 1189612.A33Q_0201 1.2e-128 466.1 Cytophagia ko:K06911 ko00000 Bacteria 47MY1@768503,4NFZD@976,COG1741@1,COG1741@2 NA|NA|NA S Belongs to the pirin family MAG.T22.3_04259 1239962.C943_00631 2.2e-190 671.4 Cytophagia desA1 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0030312,GO:0040007,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071944,GO:0075136 1.14.19.11,1.14.19.2,1.14.19.26 ko:K03921 ko00061,ko01040,ko01212,map00061,map01040,map01212 R03370,R08161,R11108,R11109 RC00917 ko00000,ko00001,ko01000,ko01004 Bacteria 47K8R@768503,4NE91@976,COG0208@1,COG0208@2 NA|NA|NA F PFAM Fatty acid desaturase MAG.T22.3_04260 1239962.C943_00632 0.0 1197.2 Cytophagia Bacteria 47K7D@768503,4NGBK@976,COG2382@1,COG2382@2 NA|NA|NA P esterase MAG.T22.3_04261 1239962.C943_00634 4.4e-233 813.5 Cytophagia 3.4.13.19 ko:K01273 ko00000,ko00537,ko01000,ko01002,ko04147 Bacteria 47JQ6@768503,4NEBG@976,COG2355@1,COG2355@2 NA|NA|NA E PFAM Membrane dipeptidase (Peptidase family M19) MAG.T22.3_04262 1239962.C943_00635 7e-85 320.1 Cytophagia Bacteria 47KP1@768503,4PKIS@976,COG4339@1,COG4339@2 NA|NA|NA S PFAM Metal-dependent phosphohydrolase, HD MAG.T22.3_04263 1239962.C943_00636 5.1e-182 643.7 Cytophagia Bacteria 28M5H@1,2ZAJ9@2,47TNT@768503,4NESS@976 NA|NA|NA MAG.T22.3_04264 1239962.C943_00637 0.0 1429.5 Cytophagia Bacteria 47JK1@768503,4NF6J@976,COG0507@1,COG0507@2 NA|NA|NA L PIF1-like helicase MAG.T22.3_04265 1239962.C943_00638 1.5e-124 452.2 Cytophagia 1.1.1.325 ko:K17745 ko00790,map00790 M00843 R09989,R09990 RC00823,RC02162 ko00000,ko00001,ko00002,ko01000 Bacteria 47M5I@768503,4NG8J@976,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family MAG.T22.3_04266 1239962.C943_00639 0.0 1315.8 Cytophagia ispG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 iAF1260.b2515,iAPECO1_1312.APECO1_4009,iB21_1397.B21_02369,iBWG_1329.BWG_2279,iE2348C_1286.E2348C_2798,iEC55989_1330.EC55989_2800,iECABU_c1320.ECABU_c28200,iECBD_1354.ECBD_1171,iECB_1328.ECB_02407,iECDH10B_1368.ECDH10B_2681,iECDH1ME8569_1439.ECDH1ME8569_2442,iECDH1ME8569_1439.EcDH1_1153,iECD_1391.ECD_02407,iECED1_1282.ECED1_2946,iECH74115_1262.ECH74115_3740,iECIAI39_1322.ECIAI39_2716,iECNA114_1301.ECNA114_2593,iECO103_1326.ECO103_3032,iECO111_1330.ECO111_3239,iECO26_1355.ECO26_3562,iECOK1_1307.ECOK1_2863,iECP_1309.ECP_2520,iECS88_1305.ECS88_2691,iECSE_1348.ECSE_2801,iECSF_1327.ECSF_2359,iECSP_1301.ECSP_3455,iECW_1372.ECW_m2740,iECs_1301.ECs3377,iEKO11_1354.EKO11_1218,iETEC_1333.ETEC_2672,iEcDH1_1363.EcDH1_1153,iEcE24377_1341.EcE24377A_2799,iEcolC_1368.EcolC_1162,iHN637.CLJU_RS06430,iIT341.HP0625,iJN678.gcpE,iJO1366.b2515,iJR904.b2515,iLF82_1304.LF82_1130,iNRG857_1313.NRG857_12515,iUMN146_1321.UM146_04130,iUMNK88_1353.UMNK88_3165,iUTI89_1310.UTI89_C2836,iWFL_1372.ECW_m2740,iY75_1357.Y75_RS13130,iYL1228.KPN_02845,iZ_1308.Z3778,ic_1306.c3037 Bacteria 47KGW@768503,4NE63@976,COG0821@1,COG0821@2 NA|NA|NA I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate MAG.T22.3_04268 1123057.P872_08805 4.5e-48 198.4 Cytophagia Bacteria 2E380@1,31YMS@2,47RI2@768503,4NSEF@976 NA|NA|NA S TIGRFAM Porphyromonas gingivalis paralogous family TIGR01200 MAG.T22.3_04269 1048983.EL17_04570 3.1e-167 595.9 Cytophagia Bacteria 47Y6P@768503,4NF6X@976,COG1629@1,COG1629@2 NA|NA|NA P transport MAG.T22.3_04270 1239962.C943_00641 1.3e-64 252.3 Bacteria ko:K07032 ko00000 Bacteria COG3607@1,COG3607@2 NA|NA|NA MAG.T22.3_04271 1239962.C943_00642 2.7e-53 214.5 Bacteria Bacteria COG5646@1,COG5646@2 NA|NA|NA S Domain of unknown function (DU1801) MAG.T22.3_04275 1239962.C943_00646 1.2e-75 289.3 Cytophagia rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 47PR5@768503,4NNY8@976,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family MAG.T22.3_04276 1239962.C943_00647 1.4e-98 365.5 Cytophagia rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 ko:K02860 ko00000,ko03009 Bacteria 47QUB@768503,4NQF0@976,COG0806@1,COG0806@2 NA|NA|NA J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes MAG.T22.3_04277 1239962.C943_00648 3.1e-124 451.1 Cytophagia trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 47MGG@768503,4NF2Q@976,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family MAG.T22.3_04278 1239962.C943_00649 2.3e-60 238.0 Cytophagia rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 47QAS@768503,4NNPW@976,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site MAG.T22.3_04281 1239962.C943_00652 1.2e-209 735.7 Bacteroidetes Bacteria 2CGWC@1,339HX@2,4NX41@976 NA|NA|NA MAG.T22.3_04284 1239962.C943_00654 1.3e-295 1021.5 Cytophagia gltX 6.1.1.17,6.1.1.24 ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Bacteria 47K3J@768503,4NEED@976,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) MAG.T22.3_04285 1239962.C943_00655 6.9e-28 129.4 Cytophagia Bacteria 2E4W4@1,32ZQB@2,47RZI@768503,4NUZZ@976 NA|NA|NA MAG.T22.3_04286 1239962.C943_00656 0.0 1735.7 Cytophagia Bacteria 47PTS@768503,4NMTD@976,COG1629@1,COG1629@2 NA|NA|NA P CarboxypepD_reg-like domain MAG.T22.3_04287 1239962.C943_00657 2.5e-118 431.4 Cytophagia Bacteria 2BSYX@1,32N2S@2,47PX2@768503,4PJX3@976 NA|NA|NA S Outer membrane protein beta-barrel domain MAG.T22.3_04288 1239962.C943_00658 2.6e-103 381.3 Cytophagia nifU Bacteria 47PV2@768503,4NG0Q@976,COG0694@1,COG0694@2 NA|NA|NA O PFAM Scaffold protein Nfu NifU N terminal MAG.T22.3_04289 1239962.C943_00659 7e-179 633.3 Bacteroidetes Bacteria 28HHD@1,2Z7T3@2,4NGWB@976 NA|NA|NA S Psort location CytoplasmicMembrane, score MAG.T22.3_04290 1239962.C943_00660 1.2e-129 469.2 Cytophagia pdxJ GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 Bacteria 47K7U@768503,4NF4Z@976,COG0854@1,COG0854@2 NA|NA|NA H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate MAG.T22.3_04291 1239962.C943_00661 1.4e-67 262.3 Cytophagia yqeY ko:K09117 ko00000 Bacteria 47QJ2@768503,4NQFI@976,COG1610@1,COG1610@2 NA|NA|NA S PFAM Yqey-like protein MAG.T22.3_04292 1239962.C943_00662 1.4e-90 339.0 Bacteria cvpA ko:K03558 ko00000 Bacteria COG1286@1,COG1286@2 NA|NA|NA S toxin biosynthetic process MAG.T22.3_04293 1239962.C943_00663 3.2e-101 374.4 Cytophagia trpG GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.4.2.18,2.6.1.85,4.1.3.27 ko:K01658,ko:K01664,ko:K13497 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01073,R01716 RC00010,RC00440,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 iIT341.HP1281,iSBO_1134.SBO_1803,iSbBS512_1146.SbBS512_E1488,iYL1228.KPN_01256 Bacteria 47PTT@768503,4NNU1@976,COG0512@1,COG0512@2 NA|NA|NA EH TIGRFAM glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase MAG.T22.3_04294 1239962.C943_00664 1.1e-116 426.0 Cytophagia Bacteria 47PRP@768503,4NF8G@976,COG0517@1,COG0517@2 NA|NA|NA S PFAM CBS domain MAG.T22.3_04295 1239962.C943_00665 4.9e-162 577.0 Cytophagia nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895 Bacteria 47KI4@768503,4NFG5@976,COG0061@1,COG0061@2 NA|NA|NA G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP MAG.T22.3_04296 1239962.C943_00667 5.3e-141 506.9 Cytophagia ko:K12976 ko00000,ko01000,ko01005 Bacteria 47PKF@768503,4NF6B@976,COG3637@1,COG3637@2 NA|NA|NA M Outer membrane protein beta-barrel domain MAG.T22.3_04297 1239962.C943_00668 3.1e-133 481.1 Cytophagia uppS GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 R06447,R09244,R09731 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 iLJ478.TM1398 Bacteria 47MC0@768503,4NF2B@976,COG0020@1,COG0020@2 NA|NA|NA I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids MAG.T22.3_04298 1239962.C943_00669 0.0 1747.3 Cytophagia bamA GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 ko:K07277 ko00000,ko02000,ko03029 1.B.33 Bacteria 47JEC@768503,4NE6Z@976,COG4775@1,COG4775@2 NA|NA|NA M Outer membrane protein assembly complex, YaeT protein MAG.T22.3_04299 1239962.C943_00670 5.2e-90 337.0 Cytophagia ompH ko:K06142 ko00000 Bacteria 47PD1@768503,4NH46@976,COG2825@1,COG2825@2 NA|NA|NA M PFAM Outer membrane protein (OmpH-like) MAG.T22.3_04300 1239962.C943_00671 4.9e-67 260.8 Cytophagia ompH ko:K06142 ko00000 Bacteria 47QWE@768503,4NQHJ@976,COG2825@1,COG2825@2 NA|NA|NA M PFAM Outer membrane protein (OmpH-like) MAG.T22.3_04302 1239962.C943_00674 8.5e-53 212.6 Bacteria trxM1 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8,5.3.4.1 ko:K01829,ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Bacteria COG3118@1,COG3118@2 NA|NA|NA O belongs to the thioredoxin family MAG.T22.3_04304 880070.Cycma_2978 0.0 1191.4 Cytophagia Bacteria 47KAA@768503,4NE5D@976,COG3209@1,COG3209@2 NA|NA|NA M TIGRFAM RHS repeat-associated core domain MAG.T22.3_04306 1048983.EL17_24035 7.3e-99 369.0 Cytophagia Bacteria 47Q14@768503,4NHYT@976,COG3209@1,COG3209@2 NA|NA|NA M TIGRFAM YD repeat MAG.T22.3_04307 1048983.EL17_24010 2.1e-55 223.0 Cytophagia Bacteria 47RJE@768503,4NSYI@976,COG1044@1,COG1044@2 NA|NA|NA M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell MAG.T22.3_04309 1239962.C943_03876 1.2e-26 125.2 Cytophagia Bacteria 2DP5Z@1,330NW@2,47SP6@768503,4NV0Q@976 NA|NA|NA # 3884 queries scanned # Total time (seconds): 4.48207402229 # Rate: 866.56 q/s