# emapper version: emapper-2.0.1 emapper DB: 2.0 # command: ./emapper.py -m diamond --seed_ortholog_evalue 0.00001 --data_dir /home/bayegy/Databases/emapper/data_dir2.0.1/ --cpu 30 --temp_dir /media/bayegy/disk2/bayegy/pipeline_demos/binning/share2/Bin_all/emapper//MAG.T22.42/_tmp -i /media/bayegy/disk2/bayegy/pipeline_demos/binning/share2/Bin_all/Bin_prokka//MAG.T22.42/MAG.T22.42.faa -o /media/bayegy/disk2/bayegy/pipeline_demos/binning/share2/Bin_all/emapper//MAG.T22.42/MAG.T22.42 --usemem --override # time: Wed Feb 25 23:36:25 2026 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction taxonomic scope eggNOG OGs best eggNOG OG COG Functional cat. eggNOG free text desc. MAG.T22.42_00001 401526.TcarDRAFT_1099 1.2e-10 73.2 Firmicutes Bacteria 1VZAC@1239,2ABAI@1,310R4@2 NA|NA|NA MAG.T22.42_00002 1120959.ATXF01000007_gene2095 3.5e-74 284.3 Microbacteriaceae rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GMVW@201174,4FKHJ@85023,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA MAG.T22.42_00003 1001240.GY21_00905 3e-60 237.7 Microbacteriaceae rpsL GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02950 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHUF@201174,4FNRI@85023,COG0048@1,COG0048@2 NA|NA|NA J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit MAG.T22.42_00004 1001240.GY21_08445 8.2e-53 214.2 Microbacteriaceae rfbN ko:K12992 ko02025,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 GT2 Bacteria 2I5RN@201174,4FM6Z@85023,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 2 MAG.T22.42_00005 1121924.ATWH01000005_gene2806 1.1e-114 420.2 Microbacteriaceae wbbX ko:K20444 ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 2IDYC@201174,4FPG6@85023,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups MAG.T22.42_00006 1121924.ATWH01000005_gene2797 1.3e-106 393.3 Actinobacteria wecE GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005976,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016740,GO:0016769,GO:0019180,GO:0019842,GO:0030170,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046378,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901576 2.6.1.59 ko:K02805 ko00000,ko01000,ko01007 iE2348C_1286.E2348C_4092,iEC55989_1330.EC55989_4263,iECIAI1_1343.ECIAI1_3978,iECIAI39_1322.ECIAI39_2996,iECO103_1326.ECO103_4373,iECO111_1330.ECO111_4617,iECO26_1355.ECO26_4795,iECUMN_1333.ECUMN_4316,iECW_1372.ECW_m4089,iEKO11_1354.EKO11_4565,iSSON_1240.SSON_3963,iWFL_1372.ECW_m4089 Bacteria 2GKD7@201174,COG0399@1,COG0399@2 NA|NA|NA E Belongs to the DegT DnrJ EryC1 family MAG.T22.42_00007 1120960.ATXG01000012_gene3752 3.6e-69 268.1 Microbacteriaceae Bacteria 2BCTU@1,2IFQR@201174,326EE@2,4FNG0@85023 NA|NA|NA MAG.T22.42_00008 1416759.AYMR01000007_gene772 6.7e-15 87.4 Microbacteriaceae Bacteria 2BF9D@1,2GWAC@201174,32929@2,4FQCN@85023 NA|NA|NA MAG.T22.42_00009 1120960.ATXG01000012_gene3767 2.6e-49 202.6 Microbacteriaceae Bacteria 2CFU6@1,2INNW@201174,3468F@2,4FPDN@85023 NA|NA|NA MAG.T22.42_00010 1120960.ATXG01000012_gene3768 1.2e-32 146.7 Microbacteriaceae Bacteria 2B5XH@1,2H18A@201174,31YTH@2,4FQPM@85023 NA|NA|NA MAG.T22.42_00011 1449058.JQKT01000009_gene70 9.4e-58 229.6 Microbacteriaceae rpoC GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2GKWF@201174,4FKFY@85023,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates MAG.T22.42_00012 258533.BN977_05351 4.3e-92 344.0 Mycobacteriaceae nrdF GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0030145,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iECNA114_1301.ECNA114_2708,iECSF_1327.ECSF_2473,iSFV_1184.SFV_2827,iSF_1195.SF2704,iSFxv_1172.SFxv_2966,iS_1188.S2890 Bacteria 234XW@1762,2GK46@201174,COG0208@1,COG0208@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides MAG.T22.42_00013 1122185.N792_03595 1.7e-153 549.3 Xanthomonadales ko:K07576 ko00000 Bacteria 1MUDD@1224,1RPZC@1236,1X3Y9@135614,COG1236@1,COG1236@2 NA|NA|NA J Beta-Casp domain MAG.T22.42_00014 1123013.AUIC01000004_gene1664 1.8e-69 269.6 Microbacteriaceae corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 2GKNZ@201174,4FRS7@85023,COG0598@1,COG0598@2 NA|NA|NA P CorA-like Mg2+ transporter protein MAG.T22.42_00015 1349820.M707_13275 1.7e-55 222.2 Actinobacteria yjhE Bacteria 2C3KP@1,2IFTZ@201174,2Z802@2 NA|NA|NA S phage tail protein MAG.T22.42_00016 529884.Rhola_00003090 1.5e-45 189.5 Microbacteriaceae ko:K05595 ko00000,ko02000 2.A.95.1 Bacteria 2GMCM@201174,4FT0S@85023,COG2095@1,COG2095@2 NA|NA|NA U MarC family integral membrane protein MAG.T22.42_00017 529884.Rhola_00002720 1.3e-52 212.6 Microbacteriaceae Bacteria 2C1WM@1,2IFE8@201174,32R9A@2,4FRZ3@85023 NA|NA|NA MAG.T22.42_00018 529884.Rhola_00002770 3e-50 204.5 Microbacteriaceae gloA5 3.6.3.21 ko:K02028,ko:K07032 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 2IKVS@201174,4FPVJ@85023,COG3607@1,COG3607@2 NA|NA|NA S glyoxalase bleomycin resistance protein dioxygenase MAG.T22.42_00019 1235279.C772_00768 1.6e-09 69.3 Planococcaceae frataxin ko:K05937 ko00000 Bacteria 1V6QT@1239,26FBX@186818,4HIUI@91061,COG5646@1,COG5646@2 NA|NA|NA S Domain of unknown function (DU1801) MAG.T22.42_00022 1122622.ATWJ01000012_gene1103 1.3e-99 369.8 Intrasporangiaceae f42a Bacteria 2GM0Z@201174,4FG6P@85021,COG0330@1,COG0330@2 NA|NA|NA O prohibitin homologues MAG.T22.42_00024 1120960.ATXG01000013_gene3417 1.4e-204 719.5 Microbacteriaceae dnaX GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJKA@201174,4FKJQ@85023,COG2812@1,COG2812@2 NA|NA|NA L dna polymerase iii is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. this dna polymerase also exhibits 3 to 5 exonuclease activity MAG.T22.42_00025 1120959.ATXF01000011_gene208 1.6e-92 345.5 Microbacteriaceae recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2GJY0@201174,4FM54@85023,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO MAG.T22.42_00026 1120959.ATXF01000011_gene211 2.1e-169 602.1 Microbacteriaceae ask 1.1.1.3,2.7.2.4 ko:K00928,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN0G@201174,4FK80@85023,COG0527@1,COG0527@2 NA|NA|NA E ACT domain MAG.T22.42_00027 1120959.ATXF01000011_gene212 1.3e-148 532.7 Microbacteriaceae asd GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv3708c Bacteria 2GJJ8@201174,4FKI5@85023,COG0136@1,COG0136@2 NA|NA|NA E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate MAG.T22.42_00028 1177594.MIC448_600003 8.5e-57 227.3 Microbacteriaceae Bacteria 2ICPT@201174,4FNNU@85023,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal MAG.T22.42_00029 1120959.ATXF01000011_gene231 3.9e-204 717.6 Microbacteriaceae mqo 1.1.5.4 ko:K00116 ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R00360,R00361,R01257 RC00031 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJZ8@201174,4FKKD@85023,COG0579@1,COG0579@2 NA|NA|NA C oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor MAG.T22.42_00030 1348338.ADILRU_0330 1.6e-77 295.8 Microbacteriaceae tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 iAF1260.b1238,iBWG_1329.BWG_1065,iECDH10B_1368.ECDH10B_1298,iECDH1ME8569_1439.ECDH1ME8569_1176,iEcDH1_1363.EcDH1_2411,iJO1366.b1238,iJR904.b1238,iPC815.YPO2176,iY75_1357.Y75_RS06470 Bacteria 2GP1W@201174,4FND0@85023,COG1435@1,COG1435@2 NA|NA|NA F Thymidine kinase MAG.T22.42_00031 1121924.ATWH01000009_gene120 9.9e-62 243.4 Microbacteriaceae Bacteria 2I8Y7@201174,4FNIP@85023,COG2197@1,COG2197@2 NA|NA|NA T cheY-homologous receiver domain MAG.T22.42_00032 1001240.GY21_04335 1.6e-35 157.1 Microbacteriaceae Bacteria 2IHW0@201174,4FTIW@85023,COG3850@1,COG3850@2,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase-like ATPases MAG.T22.42_00033 1001240.GY21_04335 2.5e-24 119.8 Microbacteriaceae Bacteria 2IHW0@201174,4FTIW@85023,COG3850@1,COG3850@2,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase-like ATPases MAG.T22.42_00035 1120960.ATXG01000013_gene3479 8.8e-98 363.6 Microbacteriaceae ykuE ko:K07098 ko00000 Bacteria 2GJHT@201174,4FM08@85023,COG1408@1,COG1408@2 NA|NA|NA S Calcineurin-like phosphoesterase MAG.T22.42_00036 1120960.ATXG01000013_gene3480 4.3e-275 954.1 Microbacteriaceae pon1 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 2GK21@201174,4FMES@85023,COG0744@1,COG0744@2 NA|NA|NA M Transglycosylase MAG.T22.42_00037 1151126.AQYI01000005_gene2515 2.7e-24 117.5 Microbacteriaceae Bacteria 2E3JZ@1,2GQIX@201174,32YI8@2,4FPZD@85023 NA|NA|NA MAG.T22.42_00038 1123320.KB889692_gene159 1.9e-48 198.7 Actinobacteria Bacteria 2IHNE@201174,COG0251@1,COG0251@2 NA|NA|NA J endoribonuclease L-PSP MAG.T22.42_00039 1120959.ATXF01000011_gene256 6.6e-308 1062.8 Microbacteriaceae acsA 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GJCG@201174,4FMIC@85023,COG0365@1,COG0365@2 NA|NA|NA I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA MAG.T22.42_00040 1121952.ATXT01000017_gene767 8.9e-80 303.9 Microbacteriaceae cpaF ko:K02283 ko00000,ko02035,ko02044 Bacteria 2GKKJ@201174,4FN08@85023,COG4962@1,COG4962@2 NA|NA|NA U Type II/IV secretion system protein MAG.T22.42_00041 312284.A20C1_11934 1.3e-28 133.7 Bacteria ko:K12510 ko00000,ko02044 Bacteria COG4965@1,COG4965@2 NA|NA|NA U Type ii secretion system MAG.T22.42_00042 288705.RSal33209_2751 3.5e-09 67.0 Micrococcaceae Bacteria 1WAAR@1268,2EHCF@1,2HTCM@201174,33B4A@2 NA|NA|NA S Protein of unknown function (DUF4244) MAG.T22.42_00044 1120960.ATXG01000013_gene3490 0.0 1236.5 Microbacteriaceae topA GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 2GJU7@201174,4FKSY@85023,COG0550@1,COG0550@2,COG1754@1,COG1754@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone MAG.T22.42_00045 1449058.JQKT01000007_gene666 1.1e-78 299.7 Microbacteriaceae tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNTI@201174,4FMR0@85023,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis MAG.T22.42_00046 1120959.ATXF01000011_gene265 1.2e-128 466.5 Microbacteriaceae holB GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJ8C@201174,4FM8E@85023,COG0470@1,COG0470@2 NA|NA|NA L DNA polymerase III, delta subunit MAG.T22.42_00047 1416759.AYMR01000030_gene2343 3.3e-174 618.2 Microbacteriaceae slpD Bacteria 2GJYS@201174,4FMNA@85023,COG0596@1,COG0596@2 NA|NA|NA S TAP-like protein MAG.T22.42_00048 1150399.AQYK01000001_gene995 1.1e-27 130.2 Microbacteriaceae Bacteria 2HG87@201174,4FPC7@85023,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family MAG.T22.42_00050 1120960.ATXG01000001_gene707 4.7e-36 157.5 Microbacteriaceae Bacteria 2IMUX@201174,4FP1Z@85023,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein MAG.T22.42_00051 1121924.ATWH01000023_gene3214 3.6e-75 288.1 Microbacteriaceae Bacteria 2IAQJ@201174,4FMER@85023,COG0745@1,COG0745@2 NA|NA|NA KT Transcriptional regulatory protein, C terminal MAG.T22.42_00052 1120960.ATXG01000001_gene735 1.7e-92 345.5 Microbacteriaceae upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000 Bacteria 2GPJE@201174,4FKA4@85023,COG0035@1,COG0035@2 NA|NA|NA F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate MAG.T22.42_00053 1416759.AYMR01000005_gene3658 2.4e-43 181.8 Microbacteriaceae tadA 3.5.4.1,3.5.4.33,3.8.1.5,6.3.4.19 ko:K01485,ko:K01563,ko:K04075,ko:K11991 ko00240,ko00330,ko00361,ko00625,ko01100,ko01120,map00240,map00330,map00361,map00625,map01100,map01120 R00974,R01411,R02922,R05284,R05367,R05368,R05369,R05370,R07669,R07670,R09597,R10223 RC00074,RC00477,RC00514,RC00809,RC01317,RC01340,RC01341,RC02013,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 2IM3Z@201174,4FPAS@85023,COG0590@1,COG0590@2 NA|NA|NA FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) MAG.T22.42_00054 1150399.AQYK01000001_gene485 2.6e-124 451.8 Microbacteriaceae cat Bacteria 2GKSG@201174,4FKQB@85023,COG0053@1,COG0053@2 NA|NA|NA P Cation efflux family MAG.T22.42_00055 1121372.AULK01000004_gene1236 7.1e-86 323.9 Microbacteriaceae proC 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ7D@201174,4FKI6@85023,COG0345@1,COG0345@2 NA|NA|NA E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline MAG.T22.42_00057 76636.JOEC01000004_gene1327 1.2e-31 142.9 Microbacteriaceae ko:K03892 ko00000,ko03000 Bacteria 2IQH9@201174,4FPR4@85023,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor MAG.T22.42_00058 1416759.AYMR01000005_gene3667 2.2e-19 101.3 Microbacteriaceae Bacteria 2I1DG@201174,4FPZB@85023,COG0695@1,COG0695@2 NA|NA|NA O Glutaredoxin-like domain (DUF836) MAG.T22.42_00059 1001240.GY21_12365 3e-16 90.5 Microbacteriaceae Bacteria 2GQGV@201174,4FQ2D@85023,COG3311@1,COG3311@2 NA|NA|NA K Helix-turn-helix domain MAG.T22.42_00060 1120959.ATXF01000005_gene1348 1.2e-35 156.0 Microbacteriaceae Bacteria 2AY0M@1,2IMBI@201174,31Q26@2,4FPBJ@85023 NA|NA|NA S Phospholipase_D-nuclease N-terminal MAG.T22.42_00061 76636.JOEC01000004_gene1338 1.3e-203 715.7 Microbacteriaceae aspS 6.1.1.12,6.1.1.23,6.3.5.6,6.3.5.7 ko:K01876,ko:K02434,ko:K09759,ko:K22503 ko00970,ko01100,map00970,map01100 M00359,M00360 R03647,R03905,R04212,R05577 RC00010,RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2I2KQ@201174,4FKWR@85023,COG0017@1,COG0017@2 NA|NA|NA J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) MAG.T22.42_00062 1120960.ATXG01000001_gene773 1.8e-57 229.2 Microbacteriaceae 3.1.3.3,3.1.3.73 ko:K02226,ko:K22305 ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130 M00122 R00582,R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMXF@201174,4FNCD@85023,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family MAG.T22.42_00063 1121924.ATWH01000004_gene2527 1.2e-58 233.0 Microbacteriaceae resA ko:K02199 ko00000,ko03110 Bacteria 2GP7J@201174,4FNQ0@85023,COG0526@1,COG0526@2 NA|NA|NA CO Redoxin MAG.T22.42_00064 1120960.ATXG01000001_gene775 1.3e-83 316.2 Microbacteriaceae ccdA 1.8.4.11,1.8.4.12 ko:K06196,ko:K12267 ko00000,ko01000,ko02000 5.A.1.2 Bacteria 2GJW3@201174,4FMCU@85023,COG0785@1,COG0785@2 NA|NA|NA O Cytochrome C biogenesis protein transmembrane region MAG.T22.42_00065 1121924.ATWH01000004_gene2525 7.2e-183 647.1 Microbacteriaceae resB ko:K07399 ko00000 Bacteria 2GMGH@201174,4FM4B@85023,COG1333@1,COG1333@2 NA|NA|NA O ResB-like family MAG.T22.42_00066 1120959.ATXF01000006_gene1748 7.8e-116 423.7 Microbacteriaceae ccsA GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 Bacteria 2GJR1@201174,4FKNR@85023,COG0755@1,COG0755@2 NA|NA|NA O Cytochrome C assembly protein MAG.T22.42_00067 1122239.AULS01000002_gene689 8.3e-94 350.5 Microbacteriaceae menC GO:0008150,GO:0040007 4.2.1.113,5.1.1.20,5.1.1.3 ko:K01776,ko:K02549,ko:K19802 ko00130,ko00471,ko01100,ko01110,map00130,map00471,map01100,map01110 M00116 R00260,R04031,R10938 RC00302,RC01053,RC03309 ko00000,ko00001,ko00002,ko01000,ko01011 iNJ661.Rv0553,iSB619.SA_RS09080 Bacteria 2GJJR@201174,4FMB2@85023,COG4948@1,COG4948@2 NA|NA|NA M Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) MAG.T22.42_00068 443906.CMM_0576 8.4e-141 506.5 Microbacteriaceae menB GO:0003674,GO:0003824,GO:0005488,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:0071890,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07263 RC01923 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK5G@201174,4FKK4@85023,COG0447@1,COG0447@2 NA|NA|NA H Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily MAG.T22.42_00069 979556.MTES_2345 1.8e-57 229.9 Microbacteriaceae menE 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN9C@201174,4FMU9@85023,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme MAG.T22.42_00070 1120960.ATXG01000001_gene786 3.6e-92 345.1 Microbacteriaceae menA GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 iECH74115_1262.ECH74115_5387,iG2583_1286.G2583_4737 Bacteria 2GJBS@201174,4FKKS@85023,COG1575@1,COG1575@2 NA|NA|NA H Belongs to the MenA family. Type 1 subfamily MAG.T22.42_00071 1389489.O159_26380 6e-08 63.5 Microbacteriaceae Bacteria 2DZ3S@1,2GVRM@201174,34CBX@2,4FQF7@85023 NA|NA|NA S Protein of unknown function (DUF4229) MAG.T22.42_00072 1123052.AUDF01000009_gene1624 2.4e-50 205.3 Microbacteriaceae Bacteria 2GYGX@201174,4FNXE@85023,COG1853@1,COG1853@2 NA|NA|NA S Flavin reductase like domain MAG.T22.42_00073 1121924.ATWH01000004_gene2509 6.5e-15 86.7 Microbacteriaceae Bacteria 2EGDD@1,2GR3X@201174,33A58@2,4FQ16@85023 NA|NA|NA S Phospholipase_D-nuclease N-terminal MAG.T22.42_00074 1120960.ATXG01000001_gene789 1.9e-133 483.0 Microbacteriaceae menD GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.2.1.9 ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08165 RC02186 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS05085 Bacteria 2GMEB@201174,4FK5P@85023,COG1165@1,COG1165@2 NA|NA|NA H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) MAG.T22.42_00075 1111131.HMPREF1255_0772 4.6e-121 441.4 Actinobacteria ko:K07133 ko00000 Bacteria 2GK4E@201174,COG1373@1,COG1373@2 NA|NA|NA S Psort location Cytoplasmic, score MAG.T22.42_00076 1120960.ATXG01000001_gene791 6.7e-93 347.8 Microbacteriaceae menF 5.4.4.2 ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKE8@201174,4FKPD@85023,COG1169@1,COG1169@2 NA|NA|NA HQ chorismate binding enzyme MAG.T22.42_00077 1120960.ATXG01000001_gene792 8.5e-74 283.5 Microbacteriaceae ubiE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0040007,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 iAF1260.b3833,iBWG_1329.BWG_3511,iE2348C_1286.E2348C_4147,iEC042_1314.EC042_4213,iEC55989_1330.EC55989_4310,iECDH10B_1368.ECDH10B_4024,iECDH1ME8569_1439.ECDH1ME8569_3712,iECH74115_1262.ECH74115_5274,iECIAI1_1343.ECIAI1_4028,iECIAI39_1322.ECIAI39_3162,iECO103_1326.ECO103_4330,iECO111_1330.ECO111_4661,iECO26_1355.ECO26_4752,iECSE_1348.ECSE_4121,iECSP_1301.ECSP_4888,iECUMN_1333.ECUMN_4359,iECW_1372.ECW_m4135,iECs_1301.ECs4763,iEKO11_1354.EKO11_4524,iETEC_1333.ETEC_4110,iEcDH1_1363.EcDH1_4146,iEcE24377_1341.EcE24377A_4354,iEcHS_1320.EcHS_A4057,iEcSMS35_1347.EcSMS35_4216,iEcolC_1368.EcolC_4175,iG2583_1286.G2583_4633,iJO1366.b3833,iJR904.b3833,iSBO_1134.SBO_3847,iSDY_1059.SDY_3910,iSFV_1184.SFV_3665,iSF_1195.SF3911,iSFxv_1172.SFxv_4263,iSSON_1240.SSON_4008,iS_1188.S3843,iSbBS512_1146.SbBS512_E4305,iUMNK88_1353.UMNK88_4663,iWFL_1372.ECW_m4135,iY75_1357.Y75_RS17910,iZ_1308.Z5355 Bacteria 2GKFZ@201174,4FM8H@85023,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) MAG.T22.42_00078 1120959.ATXF01000006_gene1730 4.6e-122 444.5 Microbacteriaceae hepS GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 R09247 RC00279 ko00000,ko00001,ko01000,ko01006 Bacteria 2GMB4@201174,4FM8C@85023,COG0142@1,COG0142@2 NA|NA|NA H Polyprenyl synthetase MAG.T22.42_00079 1120959.ATXF01000006_gene1729 4.2e-224 783.9 Microbacteriaceae fprA 1.18.1.2,1.19.1.1 ko:K00528 R10159 ko00000,ko01000 Bacteria 2GJ4A@201174,4FKFJ@85023,COG0493@1,COG0493@2 NA|NA|NA E Pyridine nucleotide-disulphide oxidoreductase MAG.T22.42_00080 1464048.JNZS01000007_gene4491 3.1e-108 398.3 Micromonosporales ko:K07045 ko00000 Bacteria 2GMQY@201174,4D8Y3@85008,COG2159@1,COG2159@2 NA|NA|NA S Amidohydrolase MAG.T22.42_00081 1120960.ATXG01000001_gene795 6.2e-26 124.0 Microbacteriaceae pppA 3.4.23.43 ko:K02278,ko:K02654 M00331 ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 Bacteria 2GJ7K@201174,4FNKR@85023,COG1989@1,COG1989@2 NA|NA|NA NOU Type IV leader peptidase family MAG.T22.42_00082 1120960.ATXG01000001_gene804 7.2e-101 374.0 Microbacteriaceae Bacteria 2GIVB@201174,4FM40@85023,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 MAG.T22.42_00083 1101188.KI912155_gene1252 1.5e-18 99.0 Actinobacteria ko:K07171 ko00000,ko01000,ko02048 Bacteria 2IICB@201174,COG2337@1,COG2337@2 NA|NA|NA T PemK-like, MazF-like toxin of type II toxin-antitoxin system MAG.T22.42_00084 76636.JOEC01000004_gene1385 1.5e-67 262.3 Microbacteriaceae trpF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K09767 ko00000 Bacteria 2IFIU@201174,4FNDQ@85023,COG1666@1,COG1666@2 NA|NA|NA S Protein of unknown function (DUF520) MAG.T22.42_00085 529884.Rhola_00009930 4.2e-44 184.1 Actinobacteria Bacteria 2DMPC@1,2GS3U@201174,32SVH@2 NA|NA|NA S Putative lumazine-binding MAG.T22.42_00087 1094508.Tsac_1962 3.9e-15 89.7 Thermoanaerobacterales int ko:K14059 ko00000 Bacteria 1TTJI@1239,247V6@186801,42G18@68295,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family MAG.T22.42_00092 1489678.RDMS_10975 9.5e-183 647.5 Bacteria Bacteria COG1002@1,COG1002@2 NA|NA|NA V DNA modification MAG.T22.42_00094 1122239.AULS01000002_gene774 2e-26 124.8 Microbacteriaceae Bacteria 2E8MQ@1,2GSZR@201174,332Z5@2,4FPRI@85023 NA|NA|NA S Ribbon-helix-helix protein, copG family MAG.T22.42_00095 979556.MTES_0687 0.0 1185.2 Microbacteriaceae icd 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ1C@201174,4FM5H@85023,COG2838@1,COG2838@2 NA|NA|NA C Monomeric isocitrate dehydrogenase MAG.T22.42_00096 644548.SCNU_17692 7.9e-19 100.9 Gordoniaceae Bacteria 2HRC6@201174,4GDXG@85026,COG1280@1,COG1280@2 NA|NA|NA E Sap, sulfolipid-1-addressing protein MAG.T22.42_00097 1451261.AS96_12320 1.8e-208 732.3 Microbacteriaceae Bacteria 2GJVW@201174,4FM0R@85023,COG1574@1,COG1574@2 NA|NA|NA S Amidohydrolase family MAG.T22.42_00098 1120959.ATXF01000005_gene1014 1.1e-117 429.9 Microbacteriaceae aguA 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 R01416 RC00177 ko00000,ko00001,ko01000 Bacteria 2GM6J@201174,4FMVD@85023,COG2957@1,COG2957@2 NA|NA|NA E Porphyromonas-type peptidyl-arginine deiminase MAG.T22.42_00099 1151122.AQYD01000007_gene729 1.1e-218 766.1 Microbacteriaceae gatA3 3.5.1.4,6.3.5.6,6.3.5.7 ko:K01426,ko:K02433 ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120 R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000,ko03029 Bacteria 2GMND@201174,4FMP2@85023,COG0154@1,COG0154@2 NA|NA|NA J Amidase MAG.T22.42_00100 31964.CMS3003 1.5e-72 279.6 Microbacteriaceae suhB 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJQE@201174,4FM3V@85023,COG0483@1,COG0483@2 NA|NA|NA G Inositol monophosphatase family MAG.T22.42_00102 1121924.ATWH01000004_gene2486 2e-58 232.6 Microbacteriaceae ko:K21471,ko:K21472 ko00000,ko01000,ko01002,ko01011 Bacteria 2GM7Q@201174,4FPAE@85023,COG0739@1,COG0739@2 NA|NA|NA M Peptidase family M23 MAG.T22.42_00103 1132441.KI519455_gene2809 2.3e-56 225.3 Micrococcaceae idi GO:0003674,GO:0003824,GO:0004452,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0019637,GO:0033554,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046490,GO:0050896,GO:0051716,GO:0071704,GO:0090407,GO:1901576 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 iECH74115_1262.ECH74115_4179,iECIAI1_1343.ECIAI1_3008,iECO103_1326.ECO103_3464,iECSP_1301.ECSP_3858,iECs_1301.ECs3761,iEcE24377_1341.EcE24377A_3215,iG2583_1286.G2583_3542,iSFV_1184.SFV_2937,iSF_1195.SF2875,iSFxv_1172.SFxv_3153,iSSON_1240.SSON_3042,iS_1188.S3074,iZ_1308.Z4227 Bacteria 1W94W@1268,2GM26@201174,COG1443@1,COG1443@2 NA|NA|NA I Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) MAG.T22.42_00104 443906.CMM_2888 5.9e-93 347.8 Microbacteriaceae idsA 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13787,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00365,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2IFAW@201174,4FMDH@85023,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family MAG.T22.42_00105 31964.CMS2607 1.2e-75 290.0 Microbacteriaceae crtB GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37,2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99 ko:K00801,ko:K02291,ko:K10027,ko:K10208,ko:K20611 ko00100,ko00906,ko00909,ko01062,ko01100,ko01110,ko01130,map00100,map00906,map00909,map01062,map01100,map01110,map01130 M00097 R00702,R02065,R02872,R04218,R04787,R04798,R04800,R06223,R07270,R07652,R09691,R09692,R09793,R10177 RC00362,RC00796,RC01101,RC01214,RC02088,RC02605,RC02839,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2GJAV@201174,4FMBC@85023,COG1233@1,COG1233@2,COG1562@1,COG1562@2 NA|NA|NA Q Flavin containing amine oxidoreductase MAG.T22.42_00106 1348338.ADILRU_0251 1.3e-187 662.9 Microbacteriaceae crtI 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 ko:K10027,ko:K20611 ko00906,ko01100,ko01110,map00906,map01100,map01110 R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 Bacteria 2GJAV@201174,4FMBC@85023,COG1233@1,COG1233@2 NA|NA|NA Q Flavin containing amine oxidoreductase MAG.T22.42_00107 935839.JAGJ01000001_gene1128 1.1e-21 109.4 Promicromonosporaceae crtYe ko:K03980 ko00000,ko01011,ko02000 2.A.66.4 Bacteria 2GQFT@201174,4F5XA@85017,COG3266@1,COG3266@2 NA|NA|NA S lycopene cyclase MAG.T22.42_00108 1232429.CBLL010000130_gene2284 7.6e-18 96.7 Micrococcaceae crtYf Bacteria 1WA0G@1268,2GU6R@201174,3334T@2,COG0382@1 NA|NA|NA H lycopene cyclase domain MAG.T22.42_00109 494419.ALPM01000021_gene38 2.1e-88 332.4 Micrococcaceae ubiA 2.5.1.133,2.5.1.62 ko:K04040 ko00860,ko01100,ko01110,map00860,map01100,map01110 R06284,R09067,R11514,R11517 RC00020 ko00000,ko00001,ko01000,ko01006 Bacteria 1W83U@1268,2GKJ2@201174,COG0382@1,COG0382@2 NA|NA|NA H UbiA prenyltransferase family MAG.T22.42_00112 1680.BADO_1520 5.5e-08 65.9 Bifidobacteriales Bacteria 2IE09@201174,4D2V6@85004,COG2247@1,COG2247@2,COG3209@1,COG3209@2 NA|NA|NA M Cysteine-rich secretory protein family MAG.T22.42_00113 529884.Rhola_00002470 1.1e-33 150.2 Microbacteriaceae narL ko:K07684 ko02020,map02020 M00471 ko00000,ko00001,ko00002,ko02022 Bacteria 2HSNY@201174,4FPMD@85023,COG2197@1,COG2197@2 NA|NA|NA KT helix_turn_helix, Lux Regulon MAG.T22.42_00115 1132441.KI519455_gene3423 7.3e-223 780.4 Micrococcaceae ko:K06994 ko00000 Bacteria 1W7ZU@1268,2GIRQ@201174,COG2409@1,COG2409@2 NA|NA|NA S MMPL family MAG.T22.42_00116 478801.Ksed_10230 3.5e-14 84.7 Actinobacteria Bacteria 2GVD1@201174,COG1848@1,COG1848@2 NA|NA|NA S PIN domain MAG.T22.42_00117 164757.Mjls_0815 1.7e-09 68.6 Mycobacteriaceae Bacteria 23E46@1762,2ET03@1,2HYH1@201174,30HGD@2 NA|NA|NA MAG.T22.42_00118 926569.ANT_02360 2.8e-74 285.4 Bacteria MA20_36825 1.1.1.401 ko:K21883 ko00051,ko01120,map00051,map01120 R11339 RC00089 ko00000,ko00001,ko01000 Bacteria COG4221@1,COG4221@2 NA|NA|NA IQ oxidoreductase activity MAG.T22.42_00120 312284.A20C1_13411 2.2e-104 386.0 unclassified Actinobacteria (class) 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJKT@201174,3UXCK@52018,COG0446@1,COG0446@2 NA|NA|NA S Reductase C-terminal MAG.T22.42_00121 312284.A20C1_13406 1.2e-20 105.1 Actinobacteria ko:K05337 ko00000 Bacteria 2GWHY@201174,COG1141@1,COG1141@2 NA|NA|NA C Ferredoxin MAG.T22.42_00122 312284.A20C1_13401 2.5e-137 495.0 unclassified Actinobacteria (class) 4.1.1.68 ko:K05921 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04134,R04380 RC01085,RC02669 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN2G@201174,3UWHK@52018,COG0179@1,COG0179@2 NA|NA|NA Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) MAG.T22.42_00123 312284.A20C1_13396 4.7e-115 421.0 Actinobacteria Bacteria 2GT9G@201174,COG3384@1,COG3384@2 NA|NA|NA S Catalytic LigB subunit of aromatic ring-opening dioxygenase MAG.T22.42_00124 312284.A20C1_13391 8.9e-217 759.6 unclassified Actinobacteria (class) hpaE 1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85 ko:K00130,ko:K00151,ko:K10217 ko00260,ko00350,ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00260,map00350,map00362,map00380,map00622,map01100,map01120,map01220 M00038,M00533,M00555,M00569 R02565,R02566,R02762,R03889,R04418,R05353 RC00080,RC00218,RC00254 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWZ@201174,3UWFP@52018,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family MAG.T22.42_00125 479432.Sros_7501 2.4e-42 179.1 Streptosporangiales ko:K07010 ko00000,ko01002 Bacteria 2HRHB@201174,4EN84@85012,COG2071@1,COG2071@2 NA|NA|NA S Peptidase C26 MAG.T22.42_00126 312284.A20C1_13386 8.1e-48 196.8 Actinobacteria ywaE GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 Bacteria 2IBDP@201174,COG1846@1,COG1846@2 NA|NA|NA K transcriptional regulator MAG.T22.42_00127 312284.A20C1_13381 7.2e-167 593.6 unclassified Actinobacteria (class) Bacteria 2GKCG@201174,3UX3R@52018,COG2124@1,COG2124@2 NA|NA|NA C Cytochrome P450 MAG.T22.42_00128 312284.A20C1_13366 3.9e-85 321.2 unclassified Actinobacteria (class) guaA1 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 2GNA6@201174,3UXJK@52018,COG0518@1,COG0518@2 NA|NA|NA F Peptidase C26 MAG.T22.42_00129 1348338.ADILRU_1940 2.1e-151 542.3 Microbacteriaceae 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 2GM3K@201174,4FK57@85023,COG0174@1,COG0174@2 NA|NA|NA E Glutamine synthetase, catalytic domain MAG.T22.42_00130 312284.A20C1_13351 5.6e-120 437.2 Actinobacteria Bacteria 2I55Y@201174,COG4689@1,COG4689@2 NA|NA|NA Q acetoacetate decarboxylase MAG.T22.42_00131 312284.A20C1_13346 2e-163 582.4 Actinobacteria Bacteria 2I478@201174,COG0833@1,COG0833@2 NA|NA|NA E Amino acid permease MAG.T22.42_00132 266117.Rxyl_1038 3.9e-145 521.5 Rubrobacteria 4.1.1.105,4.1.1.28 ko:K01593 ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00037,M00042 R00685,R00699,R00736,R02080,R02701,R04909 RC00299 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GK3J@201174,4CPR5@84995,COG0076@1,COG0076@2 NA|NA|NA E Pyridoxal-dependent decarboxylase conserved domain MAG.T22.42_00133 479433.Caci_5985 5.9e-11 73.6 Actinobacteria ko:K09956,ko:K12262 ko00000 Bacteria 2GSKA@201174,COG3553@1,COG3553@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2218) MAG.T22.42_00134 1120959.ATXF01000005_gene1545 1.1e-145 523.5 Microbacteriaceae pepA 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJRB@201174,4FKIB@85023,COG0260@1,COG0260@2 NA|NA|NA E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides MAG.T22.42_00135 1121372.AULK01000004_gene1143 1.6e-52 212.2 Microbacteriaceae hadA Bacteria 2GMVC@201174,4FNUQ@85023,COG2030@1,COG2030@2 NA|NA|NA I N-terminal half of MaoC dehydratase MAG.T22.42_00136 76636.JOEC01000004_gene1425 7.1e-50 203.4 Microbacteriaceae hadB Bacteria 2IFCJ@201174,4FP31@85023,COG2030@1,COG2030@2 NA|NA|NA I MaoC like domain MAG.T22.42_00137 1194165.CAJF01000005_gene2266 1.2e-99 370.2 Microbacteriaceae murB GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0022603,GO:0022604,GO:0030203,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0055114,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 iECED1_1282.ECED1_4683,iECUMN_1333.ECUMN_4498_AT6,iLF82_1304.LF82_1416,iNRG857_1313.NRG857_19845 Bacteria 2GIV2@201174,4FKEM@85023,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation MAG.T22.42_00138 1120959.ATXF01000005_gene1100 0.0 1194.5 Microbacteriaceae swrC ko:K03296,ko:K07787 ko02020,map02020 ko00000,ko00001,ko02000 2.A.6.1.4,2.A.6.2 Bacteria 2GMQX@201174,4FK8V@85023,COG0841@1,COG0841@2 NA|NA|NA V AcrB/AcrD/AcrF family MAG.T22.42_00139 1120959.ATXF01000005_gene1093 9.7e-108 396.7 Microbacteriaceae hutG 3.5.3.11,3.5.3.8 ko:K01479,ko:K01480 ko00330,ko00340,ko01100,map00330,map00340,map01100 M00045,M00133 R01157,R02285 RC00024,RC00221,RC00329,RC00681 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJA6@201174,4FKS9@85023,COG0010@1,COG0010@2 NA|NA|NA E Arginase family MAG.T22.42_00140 1120959.ATXF01000005_gene1090 1.1e-156 559.7 Microbacteriaceae hutI GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJH4@201174,4FKFI@85023,COG1228@1,COG1228@2 NA|NA|NA Q Amidohydrolase family MAG.T22.42_00141 1150399.AQYK01000002_gene3329 1.8e-274 951.4 Microbacteriaceae hutU 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 Bacteria 2GP10@201174,4FK8Q@85023,COG2987@1,COG2987@2 NA|NA|NA E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate MAG.T22.42_00142 1120960.ATXG01000004_gene1782 6.5e-218 763.5 Microbacteriaceae hutH 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJZW@201174,4FMRY@85023,COG2986@1,COG2986@2 NA|NA|NA E Aromatic amino acid lyase MAG.T22.42_00143 1120959.ATXF01000005_gene1084 1.9e-82 312.4 Microbacteriaceae Bacteria 2GM23@201174,4FMI6@85023,COG1414@1,COG1414@2 NA|NA|NA K Bacterial transcriptional regulator MAG.T22.42_00145 1389489.O159_02070 7e-186 657.5 Microbacteriaceae deaD 3.6.4.13 ko:K05592,ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2GIUR@201174,4FMCE@85023,COG0513@1,COG0513@2 NA|NA|NA L helicase superfamily c-terminal domain MAG.T22.42_00146 1120959.ATXF01000005_gene1031 9.2e-50 204.1 Microbacteriaceae fkbB 5.2.1.8 ko:K01802 ko00000,ko01000 Bacteria 2GJK2@201174,4FPD1@85023,COG0545@1,COG0545@2 NA|NA|NA O FKBP-type peptidyl-prolyl cis-trans isomerase MAG.T22.42_00147 1081644.IMCC13023_07420 2.6e-32 145.6 Microbacteriaceae narL ko:K07684 ko02020,map02020 M00471 ko00000,ko00001,ko00002,ko02022 Bacteria 2HSNY@201174,4FPMD@85023,COG2197@1,COG2197@2 NA|NA|NA KT helix_turn_helix, Lux Regulon MAG.T22.42_00148 529884.Rhola_00002480 9.1e-19 102.1 Microbacteriaceae Bacteria 2GWSQ@201174,4FQRQ@85023,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase MAG.T22.42_00149 883066.HMPREF9233_00766 6.5e-41 175.6 Actinobacteria Bacteria 2GKIT@201174,2Z8AD@2,4D4Z1@85005,arCOG08054@1 NA|NA|NA S Carbohydrate-binding domain-containing protein Cthe_2159 MAG.T22.42_00150 1713.JOFV01000026_gene413 4.5e-50 204.5 Cellulomonadaceae Bacteria 2IIBU@201174,308PC@2,4F2D7@85016,arCOG14808@1 NA|NA|NA S Domain of unknown function (DUF4956) MAG.T22.42_00151 1452535.JARD01000022_gene3149 2.3e-62 246.9 Microbacteriaceae Bacteria 2GQ63@201174,4FTH7@85023,COG1403@1,COG1403@2 NA|NA|NA V HNH endonuclease MAG.T22.42_00152 979556.MTES_1025 9.8e-226 790.0 Microbacteriaceae gabT 2.6.1.19,2.6.1.22 ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GKVH@201174,4FMGV@85023,COG0160@1,COG0160@2,COG2334@1,COG2334@2 NA|NA|NA E Aminotransferase class-III MAG.T22.42_00153 1121934.AUDX01000007_gene1807 1e-15 90.5 Microbacteriaceae Bacteria 2B1CB@1,2ITBQ@201174,31RAA@2,4FPKN@85023 NA|NA|NA MAG.T22.42_00154 1121372.AULK01000003_gene12 4.2e-23 113.6 Microbacteriaceae XAC3035 ko:K06191 ko00000 Bacteria 2GQ85@201174,4FQ09@85023,COG0695@1,COG0695@2 NA|NA|NA O Glutaredoxin MAG.T22.42_00155 1120960.ATXG01000011_gene3598 2.8e-269 934.5 Microbacteriaceae acx 1.3.3.6 ko:K00232 ko00071,ko00592,ko01040,ko01100,ko01110,ko01212,ko03320,ko04024,ko04146,map00071,map00592,map01040,map01100,map01110,map01212,map03320,map04024,map04146 M00087,M00113 R01175,R01279,R03777,R03857,R03990,R04751,R04754,R07888,R07892,R07896,R07934,R07950 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ4X@201174,4FK6K@85023,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA oxidase MAG.T22.42_00156 1122175.ATXU01000006_gene1954 6.1e-08 62.8 Microbacteriaceae Bacteria 2AZ0Z@1,2HBJN@201174,31R73@2,4FSY1@85023 NA|NA|NA MAG.T22.42_00157 979556.MTES_0048 3.8e-25 120.2 Microbacteriaceae ko:K03704 ko00000,ko03000 Bacteria 2GQRU@201174,4FQ66@85023,COG1278@1,COG1278@2 NA|NA|NA K 'Cold-shock' DNA-binding domain MAG.T22.42_00158 1120960.ATXG01000011_gene3572 5.5e-72 278.1 Microbacteriaceae ywfM ko:K03298 ko00000,ko02000 2.A.7.3 Bacteria 2GMPJ@201174,4FNM1@85023,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family MAG.T22.42_00162 529884.Rhola_00012640 1.5e-16 94.7 Microbacteriaceae Bacteria 2GWSQ@201174,4FQRQ@85023,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase MAG.T22.42_00163 1081644.IMCC13023_07420 1.8e-47 196.1 Microbacteriaceae narL ko:K07684 ko02020,map02020 M00471 ko00000,ko00001,ko00002,ko02022 Bacteria 2HSNY@201174,4FPMD@85023,COG2197@1,COG2197@2 NA|NA|NA KT helix_turn_helix, Lux Regulon MAG.T22.42_00164 1121285.AUFK01000019_gene92 8.3e-16 90.9 Chryseobacterium Bacteria 1HZTE@117743,3ZUBT@59732,4NHMH@976,COG1345@1,COG1345@2,COG3209@1,COG3209@2 NA|NA|NA N COG3209 Rhs family protein MAG.T22.42_00166 529884.Rhola_00012660 3.6e-24 118.6 Microbacteriaceae narL ko:K07684 ko02020,map02020 M00471 ko00000,ko00001,ko00002,ko02022 Bacteria 2HSNY@201174,4FPMD@85023,COG2197@1,COG2197@2 NA|NA|NA KT helix_turn_helix, Lux Regulon MAG.T22.42_00168 1120958.AULD01000005_gene1797 5.2e-44 183.7 Microbacteriaceae trx 1.8.1.8 ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Bacteria 2I2FB@201174,4FPRH@85023,COG3118@1,COG3118@2 NA|NA|NA O Thioredoxin MAG.T22.42_00170 1121372.AULK01000001_gene1839 0.0 1915.6 Microbacteriaceae metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM5Q@201174,4FM9X@85023,COG0646@1,COG0646@2,COG1410@1,COG1410@2 NA|NA|NA E B12 binding domain MAG.T22.42_00171 1449058.JQKT01000007_gene443 2.2e-70 272.3 Microbacteriaceae GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 ko:K16783,ko:K16784,ko:K16785,ko:K16786,ko:K16787,ko:K16927 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2HT3Z@201174,4FRFZ@85023,COG0619@1,COG0619@2,COG1122@1,COG1122@2 NA|NA|NA P AAA domain, putative AbiEii toxin, Type IV TA system MAG.T22.42_00172 1449058.JQKT01000007_gene443 1.4e-87 330.9 Microbacteriaceae GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 ko:K16783,ko:K16784,ko:K16785,ko:K16786,ko:K16787,ko:K16927 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2HT3Z@201174,4FRFZ@85023,COG0619@1,COG0619@2,COG1122@1,COG1122@2 NA|NA|NA P AAA domain, putative AbiEii toxin, Type IV TA system MAG.T22.42_00173 1449058.JQKT01000007_gene444 1.4e-26 126.3 Microbacteriaceae Bacteria 2C6KF@1,2GR5I@201174,32Z59@2,4FSKS@85023 NA|NA|NA MAG.T22.42_00174 1123013.AUIC01000004_gene1886 2.4e-105 388.3 Actinobacteria ahpC 1.11.1.15 ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 2GM74@201174,COG0450@1,COG0450@2 NA|NA|NA O alkyl hydroperoxide reductase MAG.T22.42_00175 1437425.CSEC_0930 1.4e-33 150.6 Bacteria Bacteria COG1506@1,COG1506@2 NA|NA|NA E serine-type peptidase activity MAG.T22.42_00179 1121924.ATWH01000001_gene4221 1.2e-81 310.5 Microbacteriaceae pdc2 ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 2GXEC@201174,4FM7P@85023,COG0739@1,COG0739@2 NA|NA|NA M Peptidase family M23 MAG.T22.42_00180 1120960.ATXG01000011_gene3564 7.1e-78 296.6 Microbacteriaceae ppa GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944 3.6.1.1 ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 iNJ661.Rv3628 Bacteria 2GM7F@201174,4FN1T@85023,COG0221@1,COG0221@2 NA|NA|NA C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions MAG.T22.42_00181 1120959.ATXF01000005_gene872 2e-111 409.1 Microbacteriaceae tilS 2.4.2.8,6.3.4.19 ko:K00760,ko:K04075,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 2GJR4@201174,4FKUB@85023,COG0037@1,COG0037@2 NA|NA|NA D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine MAG.T22.42_00182 1151122.AQYD01000004_gene2766 3.9e-72 277.7 Microbacteriaceae hpt 2.4.2.8,6.3.4.19 ko:K00760,ko:K04075,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 2GMDZ@201174,4FM07@85023,COG0634@1,COG0634@2 NA|NA|NA F Phosphoribosyl transferase domain MAG.T22.42_00183 1120959.ATXF01000005_gene870 0.0 1079.3 Microbacteriaceae ftsH GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 2GJ4Q@201174,4FKK0@85023,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins MAG.T22.42_00184 1120960.ATXG01000011_gene3558 3.2e-69 268.1 Microbacteriaceae folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 2GP2P@201174,4FNCY@85023,COG0302@1,COG0302@2 NA|NA|NA H GTP cyclohydrolase I MAG.T22.42_00185 1120960.ATXG01000011_gene3557 3.3e-91 341.7 Microbacteriaceae folP 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503,R03504,R11037,R11073 RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJDQ@201174,4FM2T@85023,COG0294@1,COG0294@2 NA|NA|NA H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives MAG.T22.42_00186 714083.JH370377_gene15 8.3e-39 166.4 Microbacteriaceae folB GO:0008150,GO:0040007 1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8 ko:K01633,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00840 R03503,R03504,R11037,R11073 RC00002,RC00017,RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 2IHSW@201174,4FPAQ@85023,COG1539@1,COG1539@2 NA|NA|NA H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin MAG.T22.42_00187 1122238.AULR01000010_gene227 1.8e-31 142.5 Microbacteriaceae folK 2.7.6.3,4.1.2.25 ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503,R03504 RC00002,RC00017,RC00721,RC00943 ko00000,ko00001,ko00002,ko01000 Bacteria 2H3G6@201174,4FP3G@85023,COG0801@1,COG0801@2 NA|NA|NA H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) MAG.T22.42_00188 1120960.ATXG01000011_gene3554 5.4e-22 110.9 Microbacteriaceae Bacteria 2DRQG@1,2IS8G@201174,33CMQ@2,4FP4K@85023 NA|NA|NA S Protein of unknown function (DUF3180) MAG.T22.42_00189 1120959.ATXF01000005_gene862 1.7e-78 299.3 Microbacteriaceae Bacteria 2I2F6@201174,4FMJX@85023,COG5495@1,COG5495@2 NA|NA|NA S Domain of unknown function (DUF2520) MAG.T22.42_00190 351607.Acel_0211 1.4e-70 273.1 Frankiales panC GO:0000166,GO:0000287,GO:0001505,GO:0003674,GO:0003824,GO:0004592,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0019482,GO:0019752,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033317,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042133,GO:0042364,GO:0042398,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv3602c Bacteria 2GJEQ@201174,4ESFF@85013,COG0414@1,COG0414@2 NA|NA|NA H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate MAG.T22.42_00191 1120960.ATXG01000011_gene3549 2.2e-226 791.6 Microbacteriaceae lysS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b4129,iECDH1ME8569_1439.ECDH1ME8569_3989,iECW_1372.ECW_m4490,iEcDH1_1363.EcDH1_3862,iJN678.lysS,iJO1366.b4129,iWFL_1372.ECW_m4490 Bacteria 2GKE0@201174,4FKSR@85023,COG1190@1,COG1190@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family MAG.T22.42_00192 76636.JOEC01000002_gene2108 1.5e-12 78.6 Microbacteriaceae Bacteria 2CC6F@1,2GX96@201174,33HJ8@2,4FQIF@85023 NA|NA|NA MAG.T22.42_00193 1120960.ATXG01000011_gene3545 3.6e-181 641.3 Microbacteriaceae cls ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 2GM0P@201174,4FMGP@85023,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol MAG.T22.42_00194 1120960.ATXG01000011_gene3543 2.2e-28 132.1 Microbacteriaceae Bacteria 2DTIB@1,2GTYA@201174,33KGH@2,4FQ9H@85023 NA|NA|NA MAG.T22.42_00195 1120959.ATXF01000007_gene2036 0.0 1466.4 Microbacteriaceae clpC ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 2GJ77@201174,4FMQC@85023,COG0542@1,COG0542@2 NA|NA|NA O C-terminal, D2-small domain, of ClpB protein MAG.T22.42_00196 1120960.ATXG01000012_gene3785 5e-166 590.9 Microbacteriaceae deaD 3.6.4.13 ko:K05592,ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2GIUR@201174,4FK41@85023,COG0513@1,COG0513@2 NA|NA|NA L helicase superfamily c-terminal domain MAG.T22.42_00197 1120959.ATXF01000007_gene2037 1.7e-58 232.3 Microbacteriaceae argH GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 ko:K00619,ko:K14681 ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230 M00028,M00029,M00844 R00259,R01086 RC00004,RC00064,RC00445,RC00447 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0946 Bacteria 2GJBT@201174,4FNT2@85023,COG1246@1,COG1246@2 NA|NA|NA E Acetyltransferase (GNAT) domain MAG.T22.42_00198 1121889.AUDM01000003_gene2406 2e-22 114.8 Flavobacterium Bacteria 1IKDI@117743,2P0DY@237,4PKPT@976,COG3386@1,COG3386@2,COG4886@1,COG4886@2 NA|NA|NA G Domain of unknown function (DUF5122) beta-propeller MAG.T22.42_00199 1416759.AYMR01000007_gene615 9.6e-35 153.7 Microbacteriaceae Bacteria 2E5CN@1,2GM9T@201174,3304R@2,4FNKK@85023 NA|NA|NA MAG.T22.42_00200 1120959.ATXF01000007_gene2039 8.6e-53 213.0 Microbacteriaceae Bacteria 297ZZ@1,2GVPH@201174,2ZV62@2,4FQAM@85023 NA|NA|NA MAG.T22.42_00201 1120959.ATXF01000007_gene2040 1.2e-180 639.4 Microbacteriaceae radA GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K04485 ko00000,ko03400 Bacteria 2GMQ0@201174,4FKVY@85023,COG1066@1,COG1066@2 NA|NA|NA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function MAG.T22.42_00202 518635.BIFANG_02133 4e-26 126.3 Bifidobacteriales Bacteria 2I42D@201174,4D07U@85004,COG3209@1,COG3209@2,COG3757@1,COG3757@2 NA|NA|NA M hydrolase, family 25 MAG.T22.42_00204 1120959.ATXF01000007_gene2047 3.6e-30 138.3 Microbacteriaceae Bacteria 2GMPE@201174,4FP4Y@85023,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain MAG.T22.42_00205 1120959.ATXF01000007_gene2049 1.1e-37 163.3 Microbacteriaceae ypfH GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689 ko:K06999 ko00000 Bacteria 2I5NR@201174,4FNC7@85023,COG0400@1,COG0400@2 NA|NA|NA S Phospholipase/Carboxylesterase MAG.T22.42_00206 1120960.ATXG01000012_gene3808 3.9e-81 307.8 Microbacteriaceae Bacteria 2GJGZ@201174,4FK55@85023,COG1051@1,COG1051@2 NA|NA|NA F Domain of unknown function (DUF4916) MAG.T22.42_00207 1121924.ATWH01000001_gene4168 7.6e-67 260.0 Microbacteriaceae Bacteria 2I2E3@201174,4FNP6@85023,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain MAG.T22.42_00208 1194165.CAJF01000025_gene3285 5.1e-52 210.7 Microbacteriaceae MA20_23375 ko:K07043 ko00000 Bacteria 2I3WR@201174,4FNHP@85023,COG1451@1,COG1451@2 NA|NA|NA S SprT homologues. MAG.T22.42_00209 1120960.ATXG01000012_gene3773 1.5e-92 346.3 Microbacteriaceae Bacteria 2I5RE@201174,4FK5W@85023,COG4122@1,COG4122@2 NA|NA|NA S O-methyltransferase activity MAG.T22.42_00210 1120960.ATXG01000012_gene3771 0.0 2081.2 Microbacteriaceae rpoB GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2GJ81@201174,4FMB5@85023,COG0085@1,COG0085@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates MAG.T22.42_00216 1120959.ATXF01000012_gene3212 2.9e-264 917.5 Microbacteriaceae rnj GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2GIW7@201174,4FKK3@85023,COG0595@1,COG0595@2 NA|NA|NA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay MAG.T22.42_00217 1416759.AYMR01000017_gene2394 1.8e-154 552.0 Microbacteriaceae dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ34@201174,4FK6N@85023,COG0329@1,COG0329@2 NA|NA|NA EM Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) MAG.T22.42_00218 1416759.AYMR01000010_gene3934 4.4e-43 181.0 Microbacteriaceae folA GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070401,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2763c Bacteria 2IM1S@201174,4FP2J@85023,COG0262@1,COG0262@2 NA|NA|NA H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis MAG.T22.42_00219 1123258.AQXZ01000003_gene1382 2.7e-127 461.5 Nocardiaceae thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKY0@201174,4FVPC@85025,COG0207@1,COG0207@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis MAG.T22.42_00220 1120960.ATXG01000009_gene39 5e-30 137.5 Microbacteriaceae thiX 1.8.1.8 ko:K02199,ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Bacteria 2IKMI@201174,4FPGZ@85023,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin MAG.T22.42_00221 1150399.AQYK01000002_gene2494 4.8e-47 194.1 Microbacteriaceae Bacteria 2AN8T@1,2IHRU@201174,31D6V@2,4FPV0@85023 NA|NA|NA S Domain of unknown function (DUF4395) MAG.T22.42_00222 1121952.ATXT01000020_gene1703 2.4e-76 292.4 Microbacteriaceae ko:K07071 ko00000 Bacteria 2GJS0@201174,4FKS1@85023,COG1090@1,COG1090@2 NA|NA|NA S Domain of unknown function (DUF1731) MAG.T22.42_00223 1121924.ATWH01000015_gene3568 1.3e-25 122.9 Microbacteriaceae Bacteria 2IFHE@201174,4FP3N@85023,COG5010@1,COG5010@2 NA|NA|NA U COG0457 FOG TPR repeat MAG.T22.42_00224 1120959.ATXF01000012_gene3221 1.1e-63 250.0 Microbacteriaceae dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM2T@201174,4FM4W@85023,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate MAG.T22.42_00225 1120959.ATXF01000012_gene3224 1.7e-153 549.3 Microbacteriaceae pepR GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2GJZ3@201174,4FKZ4@85023,COG0612@1,COG0612@2 NA|NA|NA S Insulinase (Peptidase family M16) MAG.T22.42_00226 1122175.ATXU01000004_gene2156 0.0 1253.4 Microbacteriaceae pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 2GIT2@201174,4FK4T@85023,COG1185@1,COG1185@2 NA|NA|NA J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction MAG.T22.42_00227 1077972.ARGLB_080_01650 2.7e-131 475.3 Micrococcaceae Bacteria 1WC3A@1268,2GMBQ@201174,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T22.42_00228 1150399.AQYK01000001_gene1481 1.9e-40 171.4 Microbacteriaceae rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQA0@201174,4FP6F@85023,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome MAG.T22.42_00229 1151126.AQYI01000006_gene2951 3.2e-25 122.1 Microbacteriaceae Bacteria 2HFWX@201174,4FPX8@85023,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family MAG.T22.42_00230 570952.ATVH01000004_gene2584 1.6e-65 257.3 Rhodospirillales Bacteria 1PMMC@1224,2JV20@204441,2U0HK@28211,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family MAG.T22.42_00231 1121924.ATWH01000003_gene1421 2.4e-54 218.0 Microbacteriaceae fkb 5.2.1.8 ko:K01802,ko:K03772 ko00000,ko01000,ko03110 Bacteria 2IHQC@201174,4FP5U@85023,COG0545@1,COG0545@2 NA|NA|NA O FKBP-type peptidyl-prolyl cis-trans isomerase MAG.T22.42_00232 1120959.ATXF01000012_gene3277 5.9e-216 756.9 Microbacteriaceae aspA 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 R00490 RC00316,RC02799 ko00000,ko00001,ko01000 Bacteria 2I2HG@201174,4FKJD@85023,COG1027@1,COG1027@2 NA|NA|NA E Fumarase C C-terminus MAG.T22.42_00233 1120959.ATXF01000012_gene3287 2.6e-23 114.8 Microbacteriaceae Bacteria 2FKE1@1,2IQDK@201174,34C1E@2,4FPQW@85023 NA|NA|NA MAG.T22.42_00234 1120960.ATXG01000009_gene133 9e-151 540.0 Microbacteriaceae pitA ko:K03306 ko00000 2.A.20 Bacteria 2GJHK@201174,4FK5I@85023,COG0306@1,COG0306@2 NA|NA|NA P Phosphate transporter family MAG.T22.42_00235 1120959.ATXF01000012_gene3290 1.1e-157 562.8 Microbacteriaceae pfkA 2.7.1.11,2.7.1.90 ko:K00850,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Bacteria 2GK6W@201174,4FKAX@85023,COG0205@1,COG0205@2 NA|NA|NA G Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis MAG.T22.42_00236 1120959.ATXF01000004_gene3152 5.1e-306 1056.6 Microbacteriaceae Bacteria 2GISC@201174,4FM8B@85023,COG0553@1,COG0553@2 NA|NA|NA L SNF2 family N-terminal domain MAG.T22.42_00237 1120959.ATXF01000004_gene3148 6.1e-161 574.7 Microbacteriaceae 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 2GIRF@201174,4FKU0@85023,COG2217@1,COG2217@2 NA|NA|NA P E1-E2 ATPase MAG.T22.42_00238 979556.MTES_2676 3.3e-75 288.1 Microbacteriaceae deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 ko:K01619 ko00030,map00030 R01066 RC00436,RC00437 ko00000,ko00001,ko01000 iSB619.SA_RS00835 Bacteria 2GJIR@201174,4FM0T@85023,COG0274@1,COG0274@2 NA|NA|NA F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate MAG.T22.42_00239 1121924.ATWH01000003_gene1467 2.1e-102 379.0 Microbacteriaceae 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJCQ@201174,4FM1E@85023,COG1940@1,COG1940@2 NA|NA|NA GK ROK family MAG.T22.42_00240 1120959.ATXF01000004_gene3139 2.4e-95 355.9 Microbacteriaceae ko:K03449 ko00000,ko02000 2.A.1.17 Bacteria 2GP5W@201174,4FKYW@85023,COG2807@1,COG2807@2 NA|NA|NA P Major Facilitator Superfamily MAG.T22.42_00241 1120959.ATXF01000004_gene3138 1.9e-103 382.5 Microbacteriaceae ribF GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKQF@201174,4FM7W@85023,COG0196@1,COG0196@2 NA|NA|NA H Riboflavin kinase MAG.T22.42_00242 1151122.AQYD01000006_gene2464 9.9e-38 162.9 Microbacteriaceae Bacteria 2BX7X@1,2IKN7@201174,32RMD@2,4FP1T@85023 NA|NA|NA S membrane MAG.T22.42_00243 1001240.GY21_03640 1.5e-35 155.6 Microbacteriaceae Bacteria 2EP16@1,2HZFU@201174,33GN1@2,4FPGN@85023 NA|NA|NA MAG.T22.42_00244 1120960.ATXG01000009_gene152 3.3e-92 345.1 Microbacteriaceae truB GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 ko00000,ko01000,ko03016 Bacteria 2GJZK@201174,4FKEW@85023,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs MAG.T22.42_00245 1120960.ATXG01000009_gene153 4.9e-81 308.1 Microbacteriaceae apbA 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 2GP6K@201174,4FKUN@85023,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid MAG.T22.42_00246 1416759.AYMR01000001_gene1451 3.5e-155 555.1 Microbacteriaceae Bacteria 2HT4F@201174,4FRJG@85023,COG0471@1,COG0471@2 NA|NA|NA P Sodium:sulfate symporter transmembrane region MAG.T22.42_00247 1120960.ATXG01000007_gene319 1.6e-99 369.4 Microbacteriaceae mutY GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.37,2.1.3.15,6.4.1.2 ko:K00558,ko:K01962,ko:K01963,ko:K03575 ko00061,ko00270,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03410,ko05206,map00061,map00270,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map03410,map05206 M00035,M00082,M00376 R00742,R04386,R04858 RC00003,RC00040,RC00253,RC00332,RC00367 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 2GJD9@201174,4FK4C@85023,COG1194@1,COG1194@2 NA|NA|NA L FES MAG.T22.42_00248 1150399.AQYK01000001_gene1400 1.7e-51 208.8 Microbacteriaceae rbfA ko:K02834 ko00000,ko03009 Bacteria 2IKXP@201174,4FNPG@85023,COG0858@1,COG0858@2 NA|NA|NA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA MAG.T22.42_00249 281090.Lxx07150 0.0 1135.2 Microbacteriaceae infB ko:K02519 ko00000,ko03012,ko03029 Bacteria 2GKPH@201174,4FKBS@85023,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex MAG.T22.42_00250 1120960.ATXG01000007_gene322 1.6e-153 548.9 Microbacteriaceae nusA GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 ko:K02600 ko00000,ko03009,ko03021 Bacteria 2GJDJ@201174,4FKQZ@85023,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination MAG.T22.42_00251 1150399.AQYK01000001_gene551 3e-148 531.9 Microbacteriaceae ko:K03457 ko00000 2.A.39 Bacteria 2GJ6B@201174,4FTGH@85023,COG1457@1,COG1457@2 NA|NA|NA F Permease for cytosine/purines, uracil, thiamine, allantoin MAG.T22.42_00252 123899.JPQP01000019_gene2684 1.9e-228 798.5 Alcaligenaceae mdlC 2.2.1.6,4.1.1.7 ko:K01576,ko:K01652 ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648 RC00027,RC00106,RC00595,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 Bacteria 1MX6Q@1224,2VIGQ@28216,3T2EJ@506,COG0028@1,COG0028@2 NA|NA|NA EH Thiamine pyrophosphate enzyme, central domain MAG.T22.42_00253 1120959.ATXF01000004_gene3123 6.8e-280 969.5 Microbacteriaceae proS GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJ9G@201174,4FK88@85023,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS MAG.T22.42_00254 1416759.AYMR01000009_gene3094 5.6e-168 597.4 Microbacteriaceae ko:K14052 ko00000,ko02000 2.A.3.1.13 Bacteria 2IBSJ@201174,4FMTU@85023,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease MAG.T22.42_00255 1449058.JQKT01000007_gene521 1.3e-52 213.4 Microbacteriaceae ko:K07090 ko00000 Bacteria 2I5VT@201174,4FMK5@85023,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE MAG.T22.42_00256 1121372.AULK01000002_gene1021 2.3e-188 664.8 Microbacteriaceae ispG GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS06430,iJN678.gcpE Bacteria 2GK2S@201174,4FKJC@85023,COG0821@1,COG0821@2 NA|NA|NA I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate MAG.T22.42_00257 1120960.ATXG01000007_gene345 1.6e-127 463.0 Microbacteriaceae rseP ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJJT@201174,4FKC9@85023,COG0750@1,COG0750@2 NA|NA|NA M Peptidase family M50 MAG.T22.42_00258 1177594.MIC448_920057 5.3e-235 820.5 Microbacteriaceae recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008270,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0017117,GO:0030894,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033202,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043142,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1904949 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJSS@201174,4FM3H@85023,COG0514@1,COG0514@2 NA|NA|NA L RQC MAG.T22.42_00259 1120960.ATXG01000007_gene346 3.6e-154 551.2 Microbacteriaceae dxr GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iHN637.CLJU_RS06420,iNJ661.Rv2870c,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188 Bacteria 2GIRV@201174,4FK72@85023,COG0743@1,COG0743@2 NA|NA|NA I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) MAG.T22.42_00260 760011.Spico_0434 1.1e-11 79.3 Spirochaetes Bacteria 2JBDR@203691,COG4886@1,COG4886@2 NA|NA|NA S Listeria-Bacteroides repeat domain (List_Bact_rpt) MAG.T22.42_00261 1121087.AUCK01000018_gene1015 3.8e-06 60.1 Bacteria yxjM Bacteria COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase MAG.T22.42_00262 529884.Rhola_00013260 7.5e-27 127.5 Microbacteriaceae narL ko:K07684 ko02020,map02020 M00471 ko00000,ko00001,ko00002,ko02022 Bacteria 2HT82@201174,4FSEQ@85023,COG2197@1,COG2197@2 NA|NA|NA KT helix_turn_helix, Lux Regulon MAG.T22.42_00263 1120960.ATXG01000007_gene349 1.3e-80 306.6 Microbacteriaceae Bacteria 2HYIN@201174,4FMTD@85023,COG5479@1,COG5479@2 NA|NA|NA M Belongs to the 5'-nucleotidase family MAG.T22.42_00264 1001240.GY21_11480 4.5e-74 284.6 Microbacteriaceae Bacteria 2GKJ6@201174,4FKU2@85023,COG1024@1,COG1024@2 NA|NA|NA I Enoyl-CoA hydratase/isomerase MAG.T22.42_00265 1429046.RR21198_3934 6.3e-136 491.1 Nocardiaceae Bacteria 2GNT8@201174,4FZ68@85025,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter MAG.T22.42_00266 1205680.CAKO01000042_gene5349 3.3e-39 169.1 Proteobacteria ko:K07001 ko00000 Bacteria 1MZJI@1224,COG1752@1,COG1752@2 NA|NA|NA S Patatin-like phospholipase MAG.T22.42_00267 700508.D174_05790 8e-19 102.4 Mycobacteriaceae yccS_1 Bacteria 236YX@1762,2GN9U@201174,COG1289@1,COG1289@2 NA|NA|NA S Fusaric acid resistance protein-like MAG.T22.42_00268 1122933.JNIY01000003_gene727 1.7e-51 210.3 Cellulomonadaceae ko:K03281 ko00000 2.A.49 Bacteria 2GJHP@201174,4F2KU@85016,COG0038@1,COG0038@2 NA|NA|NA P Voltage gated chloride channel MAG.T22.42_00269 1205910.B005_3999 5.3e-71 274.2 Streptosporangiales ung GO:0003674,GO:0003824,GO:0004844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJ9Z@201174,4EIBK@85012,COG0692@1,COG0692@2 NA|NA|NA L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine MAG.T22.42_00270 1150399.AQYK01000001_gene1183 4e-48 198.4 Microbacteriaceae kcsA ko:K10716 ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 Bacteria 2GKNF@201174,4FPYW@85023,COG1226@1,COG1226@2 NA|NA|NA P Ion transport protein MAG.T22.42_00271 1298860.AUEM01000005_gene2965 1.6e-79 302.8 Microbacteriaceae sdh Bacteria 2GMGQ@201174,4FMMA@85023,COG4221@1,COG4221@2 NA|NA|NA S Enoyl-(Acyl carrier protein) reductase MAG.T22.42_00272 1416759.AYMR01000001_gene1534 9.2e-213 746.1 Microbacteriaceae metY 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 iNJ661.Rv3340 Bacteria 2I2EB@201174,4FKGM@85023,COG2873@1,COG2873@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme MAG.T22.42_00273 1120960.ATXG01000007_gene422 5.4e-151 540.8 Microbacteriaceae metXA 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 R01776 RC00004,RC00041 ko00000,ko00001,ko01000 Bacteria 2GKNJ@201174,4FM3U@85023,COG2021@1,COG2021@2 NA|NA|NA E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine MAG.T22.42_00274 1120959.ATXF01000004_gene3038 4.7e-102 378.3 Microbacteriaceae Bacteria 2GN1J@201174,4FMWV@85023,COG5650@1,COG5650@2 NA|NA|NA S Glycosyltransferase family 87 MAG.T22.42_00275 1121924.ATWH01000003_gene1659 2.2e-55 222.6 Microbacteriaceae nnrD 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 2GJHB@201174,4FMEK@85023,COG0063@1,COG0063@2 NA|NA|NA G Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration MAG.T22.42_00276 1120959.ATXF01000004_gene3035 7.7e-125 453.8 Microbacteriaceae namA 1.6.99.1 ko:K00354 R00282 RC00001 ko00000,ko01000 Bacteria 2GK8E@201174,4FMFY@85023,COG1902@1,COG1902@2 NA|NA|NA C NADH:flavin oxidoreductase / NADH oxidase family MAG.T22.42_00277 1120960.ATXG01000007_gene435 7.3e-139 500.4 Microbacteriaceae ko:K03699 ko00000,ko02042 Bacteria 2GJ8X@201174,4FKAR@85023,COG1253@1,COG1253@2 NA|NA|NA S Domain of unknown function DUF21 MAG.T22.42_00278 1150399.AQYK01000001_gene1168 8.7e-163 580.1 Microbacteriaceae ko:K03699 ko00000,ko02042 Bacteria 2GKN5@201174,4FM5Z@85023,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain MAG.T22.42_00279 1120960.ATXG01000007_gene437 1.4e-177 629.4 Microbacteriaceae guaC GO:0003674,GO:0003824,GO:0003920,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015949,GO:0015950,GO:0015951,GO:0016020,GO:0016491,GO:0016651,GO:0016657,GO:0019637,GO:0019693,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.1.1.205,1.7.1.7 ko:K00088,ko:K00364 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R01134,R08240 RC00143,RC00457,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iEC042_1314.EC042_0103,iECIAI39_1322.ECIAI39_0105,iECUMN_1333.ECUMN_0102 Bacteria 2GNDC@201174,4FKVW@85023,COG0516@1,COG0516@2,COG0517@1,COG0517@2 NA|NA|NA F IMP dehydrogenase / GMP reductase domain MAG.T22.42_00280 1120959.ATXF01000004_gene3030 0.0 1795.8 Microbacteriaceae sucA GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 ko:K00164,ko:K01616 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1248c,iSSON_1240.SSON_0677,iYL1228.KPN_00732 Bacteria 2GIU6@201174,4FKER@85023,COG0508@1,COG0508@2,COG0567@1,COG0567@2 NA|NA|NA C 2-oxoglutarate dehydrogenase C-terminal MAG.T22.42_00281 1121952.ATXT01000017_gene914 1.4e-21 109.0 Microbacteriaceae rsrA GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 Bacteria 2GT4R@201174,4FQ4W@85023,COG5662@1,COG5662@2 NA|NA|NA K Putative zinc-finger MAG.T22.42_00282 1120959.ATXF01000004_gene3027 2.7e-71 275.0 Microbacteriaceae sigH GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K03088 ko00000,ko03021 Bacteria 2GJ02@201174,4FKHT@85023,COG1595@1,COG1595@2 NA|NA|NA K Sigma-70, region 4 MAG.T22.42_00283 1416759.AYMR01000001_gene1563 1.1e-168 599.7 Microbacteriaceae aroA GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJKX@201174,4FKIU@85023,COG0128@1,COG0128@2 NA|NA|NA E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate MAG.T22.42_00284 1120959.ATXF01000004_gene3025 1.2e-125 456.4 Microbacteriaceae rsgA 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 Bacteria 2GJ37@201174,4FKQT@85023,COG1162@1,COG1162@2 NA|NA|NA S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit MAG.T22.42_00285 1001240.GY21_12190 2.3e-57 228.4 Microbacteriaceae bcp GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0032843,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K03564 ko00000,ko01000 iPC815.YPO3064 Bacteria 2IHZ6@201174,4FNGY@85023,COG1225@1,COG1225@2 NA|NA|NA O Redoxin MAG.T22.42_00286 1150399.AQYK01000001_gene1142 3.6e-14 84.7 Microbacteriaceae Bacteria 2C28R@1,2GQ58@201174,33NYA@2,4FPSW@85023 NA|NA|NA MAG.T22.42_00287 1150399.AQYK01000001_gene1141 2.5e-39 167.5 Microbacteriaceae whiB GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K18955 ko00000,ko03000 Bacteria 2DMIE@1,2IQCG@201174,32RSG@2,4FPDC@85023 NA|NA|NA K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA MAG.T22.42_00288 1120960.ATXG01000010_gene2587 1.5e-182 646.0 Microbacteriaceae pdtaS GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 ko:K00936 M00839 ko00000,ko00002,ko01000,ko01001,ko02022 Bacteria 2GKMP@201174,4FM9A@85023,COG3920@1,COG3920@2 NA|NA|NA T Histidine kinase MAG.T22.42_00289 1120960.ATXG01000010_gene2588 6.4e-48 198.4 Microbacteriaceae Bacteria 2IARP@201174,4FMDZ@85023,COG0455@1,COG0455@2 NA|NA|NA D CobQ/CobB/MinD/ParA nucleotide binding domain MAG.T22.42_00290 1151126.AQYI01000007_gene2053 6.2e-18 97.8 Microbacteriaceae Bacteria 2GR8T@201174,4FPII@85023,COG1261@1,COG1261@2 NA|NA|NA NO SAF MAG.T22.42_00291 1121924.ATWH01000003_gene1697 3.4e-16 90.9 Microbacteriaceae Bacteria 2GR98@201174,4FQ1Q@85023,COG3311@1,COG3311@2 NA|NA|NA K Helix-turn-helix domain MAG.T22.42_00293 1348338.ADILRU_0034 5.7e-42 177.2 Microbacteriaceae Bacteria 2DPN9@1,2IR7E@201174,332RH@2,4FPM9@85023 NA|NA|NA MAG.T22.42_00294 479431.Namu_4553 2.7e-86 325.5 Bacteria Bacteria COG1075@1,COG1075@2 NA|NA|NA KLT acetyltransferases and hydrolases with the alpha beta hydrolase fold MAG.T22.42_00295 1177594.MIC448_440004 1e-142 513.1 Microbacteriaceae prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ9S@201174,4FM9U@85023,COG0462@1,COG0462@2 NA|NA|NA EF Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) MAG.T22.42_00296 1120959.ATXF01000007_gene2372 3.2e-195 688.0 Microbacteriaceae glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528,ko:K16203 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000,ko01002 3.A.1.5.2 iJN678.glmU,iLJ478.TM1629 Bacteria 2GJS1@201174,4FMW5@85023,COG1207@1,COG1207@2 NA|NA|NA M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain MAG.T22.42_00298 1121952.ATXT01000013_gene2158 8.5e-26 124.0 Bacteria 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria COG0671@1,COG0671@2 NA|NA|NA I phosphatidate phosphatase activity MAG.T22.42_00299 1120959.ATXF01000007_gene2367 1e-241 842.8 Microbacteriaceae yjjK ko:K15738 ko00000,ko02000 3.A.1.120.6 Bacteria 2GJ5M@201174,4FKBD@85023,COG0488@1,COG0488@2 NA|NA|NA S ATPases associated with a variety of cellular activities MAG.T22.42_00300 1121952.ATXT01000014_gene1434 1.7e-77 296.2 Microbacteriaceae ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.1.1.182,2.7.1.148 ko:K00919,ko:K02528,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634,R10716 RC00002,RC00003,RC01439,RC03257 ko00000,ko00001,ko00002,ko01000,ko02000,ko03009 3.A.1.29 iEC55989_1330.EC55989_1304,iLJ478.TM1383,iYO844.BSU00460 Bacteria 2GKXD@201174,4FKUE@85023,COG1947@1,COG1947@2 NA|NA|NA I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol MAG.T22.42_00301 1416759.AYMR01000007_gene712 7.7e-58 230.3 Microbacteriaceae bioN ko:K16783 ko02010,map02010 M00581 ko00000,ko00001,ko00002,ko02000 3.A.1.25.1 Bacteria 2IQMQ@201174,4FPIB@85023,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein MAG.T22.42_00302 926564.KI911619_gene4013 1.4e-82 312.8 Promicromonosporaceae cbiO ko:K02006,ko:K02008,ko:K16784,ko:K16786 ko02010,map02010 M00245,M00246,M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2GJ0M@201174,4F4KZ@85017,COG1122@1,COG1122@2 NA|NA|NA P ATPases associated with a variety of cellular activities MAG.T22.42_00303 1416759.AYMR01000007_gene716 3.3e-69 268.1 Microbacteriaceae bioY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03523 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 Bacteria 2GJ53@201174,4FNVF@85023,COG1268@1,COG1268@2 NA|NA|NA S BioY family MAG.T22.42_00304 446471.Xcel_3070 1.2e-45 189.9 Promicromonosporaceae tetR Bacteria 2HH4Y@201174,4F5M4@85017,COG1309@1,COG1309@2 NA|NA|NA K Tetracyclin repressor, C-terminal all-alpha domain MAG.T22.42_00305 1150399.AQYK01000002_gene3457 6.2e-59 234.2 Microbacteriaceae Bacteria 2HH53@201174,4FPTF@85023,COG1309@1,COG1309@2 NA|NA|NA K Tetracyclin repressor, C-terminal all-alpha domain MAG.T22.42_00306 1150399.AQYK01000002_gene3456 7.8e-185 653.7 Microbacteriaceae Bacteria 2GJVW@201174,4FMCP@85023,COG1574@1,COG1574@2 NA|NA|NA S Amidohydrolase family MAG.T22.42_00307 1150399.AQYK01000002_gene3455 7.5e-57 226.9 Microbacteriaceae Bacteria 2GNUF@201174,4FMFG@85023,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease MAG.T22.42_00308 1416759.AYMR01000036_gene3820 1.5e-102 379.4 Microbacteriaceae Bacteria 2GNUF@201174,4FMFG@85023,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease MAG.T22.42_00309 1121952.ATXT01000014_gene1433 5.6e-99 367.5 Microbacteriaceae ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182,2.1.1.184 ko:K00561,ko:K02528 R10716 RC00003,RC03257 br01600,ko00000,ko01000,ko01504,ko03009 Bacteria 2GKBT@201174,4FK5Z@85023,COG0030@1,COG0030@2 NA|NA|NA J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits MAG.T22.42_00310 1120960.ATXG01000030_gene3186 3.1e-100 371.7 Microbacteriaceae tatD ko:K03424 ko00000,ko01000 Bacteria 2GMJJ@201174,4FKYS@85023,COG0084@1,COG0084@2 NA|NA|NA L TatD related DNase MAG.T22.42_00311 1120960.ATXG01000030_gene3187 7e-236 823.2 Microbacteriaceae metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GK4S@201174,4FK9B@85023,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation MAG.T22.42_00312 1151126.AQYI01000007_gene1754 7.9e-96 357.1 Microbacteriaceae rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 2GJ9Q@201174,4FKUK@85023,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA MAG.T22.42_00313 1416759.AYMR01000018_gene2276 3.6e-174 618.2 Microbacteriaceae pmt 2.4.1.109 ko:K00728 ko00514,ko00515,ko01100,map00514,map00515,map01100 R04072,R07620,R11399 RC00005,RC00059,RC00397 ko00000,ko00001,ko01000,ko01003 GT39 Bacteria 2I2H1@201174,4FTMP@85023,COG1928@1,COG1928@2 NA|NA|NA O C-terminal four TMM region of protein-O-mannosyltransferase MAG.T22.42_00314 1120960.ATXG01000024_gene3238 2.3e-149 535.4 Microbacteriaceae apeB GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.21 ko:K01267 ko00000,ko01000,ko01002,ko04131 Bacteria 2GKW4@201174,4FKGX@85023,COG1362@1,COG1362@2 NA|NA|NA E Aminopeptidase I zinc metalloprotease (M18) MAG.T22.42_00315 1001240.GY21_04570 1.2e-93 349.7 Microbacteriaceae dkgA GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008106,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 iECH74115_1262.ECH74115_4323,iECSP_1301.ECSP_3988 Bacteria 2GJQ7@201174,4FMAU@85023,COG0656@1,COG0656@2 NA|NA|NA S Aldo/keto reductase family MAG.T22.42_00316 312284.A20C1_12244 2.3e-109 402.5 unclassified Actinobacteria (class) Bacteria 2GKMQ@201174,3UWVD@52018,COG0477@1,COG2814@2 NA|NA|NA EGP Major Facilitator Superfamily MAG.T22.42_00318 1120960.ATXG01000016_gene1472 5.3e-131 474.2 Microbacteriaceae XK27_00915 Bacteria 2GKCU@201174,4FKJ2@85023,COG2141@1,COG2141@2 NA|NA|NA C Luciferase-like monooxygenase MAG.T22.42_00319 1348338.ADILRU_0645 1.2e-36 159.8 Microbacteriaceae 3.1.3.73 ko:K02226,ko:K15640 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ9R@201174,4FP88@85023,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family MAG.T22.42_00321 1336208.JADY01000015_gene1349 2.5e-80 305.4 Rhodospirillales Bacteria 1MWJI@1224,2JSDH@204441,2TRNJ@28211,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase MAG.T22.42_00322 1120959.ATXF01000007_gene2190 2e-181 642.5 Microbacteriaceae cadA Bacteria 2GIRF@201174,4FMN0@85023,COG2217@1,COG2217@2 NA|NA|NA P E1-E2 ATPase MAG.T22.42_00325 1108045.GORHZ_006_00210 2.2e-19 102.4 Actinobacteria Bacteria 2IPD5@201174,333S7@2,arCOG08992@1 NA|NA|NA MAG.T22.42_00326 1177594.MIC448_250001 1.7e-12 80.5 Microbacteriaceae Bacteria 2EID5@1,2IH40@201174,33C4I@2,4FNJF@85023 NA|NA|NA MAG.T22.42_00327 1120960.ATXG01000016_gene1480 1.3e-51 209.5 Microbacteriaceae rimJ 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 2HAFI@201174,4FN0C@85023,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain MAG.T22.42_00328 1416759.AYMR01000018_gene2191 1e-62 246.5 Microbacteriaceae 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 Bacteria 2IKWR@201174,4FMWS@85023,COG0212@1,COG0212@2 NA|NA|NA H 5-formyltetrahydrofolate cyclo-ligase family MAG.T22.42_00329 273677.BW34_02018 2.1e-18 97.8 Microbacteriaceae fmdB Bacteria 2IQHE@201174,4FQ5K@85023,COG2331@1,COG2331@2 NA|NA|NA S Putative regulatory protein MAG.T22.42_00330 1397278.AYMV01000003_gene984 4.4e-30 137.5 Microbacteriaceae mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 2IQDN@201174,4FPI6@85023,COG1970@1,COG1970@2 NA|NA|NA M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell MAG.T22.42_00331 1120959.ATXF01000007_gene2311 0.0 1488.8 Microbacteriaceae Bacteria 2GKJW@201174,4FKCQ@85023,COG1112@1,COG1112@2 NA|NA|NA L Superfamily I DNA and RNA helicases and helicase subunits MAG.T22.42_00332 1120960.ATXG01000016_gene1489 2.3e-148 531.9 Microbacteriaceae ald 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 R00396 RC00008 ko00000,ko00001,ko01000 Bacteria 2GJ6G@201174,4FK7J@85023,COG0686@1,COG0686@2 NA|NA|NA E Belongs to the AlaDH PNT family MAG.T22.42_00333 1120959.ATXF01000007_gene2306 2.7e-59 235.0 Microbacteriaceae Bacteria 2GMSR@201174,4FPBX@85023,COG1522@1,COG1522@2 NA|NA|NA K helix_turn_helix ASNC type MAG.T22.42_00334 1120960.ATXG01000016_gene1470 5.7e-59 233.8 Microbacteriaceae ko:K07228 ko00000 Bacteria 2IFBQ@201174,4FN5Y@85023,COG0490@1,COG0490@2 NA|NA|NA P TrkA-C domain MAG.T22.42_00335 1120960.ATXG01000016_gene1471 1.7e-138 499.2 Microbacteriaceae ko:K03455 ko00000 2.A.37 Bacteria 2GJ69@201174,4FKV2@85023,COG0475@1,COG0475@2 NA|NA|NA P Sodium/hydrogen exchanger family MAG.T22.42_00336 1304876.AZVC01000004_gene3214 5.2e-78 298.1 Micrococcaceae ykiI Bacteria 1W7TR@1268,2DSXT@1,2GKR7@201174,32UTZ@2 NA|NA|NA MAG.T22.42_00337 1304876.AZVC01000001_gene1402 2.6e-36 159.1 Actinobacteria Bacteria 29YC4@1,2H0Z2@201174,30K6H@2 NA|NA|NA MAG.T22.42_00340 1120960.ATXG01000016_gene1499 1.5e-64 253.4 Microbacteriaceae Bacteria 2IICW@201174,4FNWQ@85023,COG3942@1,COG3942@2 NA|NA|NA U CHAP domain MAG.T22.42_00341 1120959.ATXF01000007_gene2300 3.3e-65 254.6 Microbacteriaceae Bacteria 2GN1W@201174,4FNDI@85023,COG1403@1,COG1403@2 NA|NA|NA V HNH endonuclease MAG.T22.42_00342 1121924.ATWH01000010_gene1025 1.1e-38 166.8 Microbacteriaceae ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 2GIWB@201174,4FNDX@85023,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family MAG.T22.42_00343 1120959.ATXF01000007_gene2298 2.3e-90 338.6 Microbacteriaceae ideR GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356,ko:K03709 M00729 ko00000,ko00002,ko01000,ko01002,ko03000,ko03400 Bacteria 2GKMC@201174,4FM1P@85023,COG1321@1,COG1321@2 NA|NA|NA K Helix-turn-helix diphteria tox regulatory element MAG.T22.42_00344 1150399.AQYK01000002_gene2771 9.7e-163 579.7 Microbacteriaceae serC GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GKYK@201174,4FMVU@85023,COG1932@1,COG1932@2 NA|NA|NA EH Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine MAG.T22.42_00345 1120959.ATXF01000007_gene2295 5.6e-21 107.8 Microbacteriaceae Bacteria 28NWB@1,2GJ74@201174,2ZBU7@2,4FP3P@85023 NA|NA|NA S Protein of unknown function (DUF3027) MAG.T22.42_00346 1416759.AYMR01000018_gene2137 2.8e-45 188.0 Microbacteriaceae cspB ko:K03704 ko00000,ko03000 Bacteria 2IKXN@201174,4FP65@85023,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein domain MAG.T22.42_00347 1120960.ATXG01000016_gene1507 1.4e-09 68.6 Microbacteriaceae Bacteria 2AYJE@1,2GY5B@201174,31QPD@2,4FQCY@85023 NA|NA|NA MAG.T22.42_00348 1120960.ATXG01000016_gene1508 4.5e-93 349.0 Microbacteriaceae Bacteria 2GURQ@201174,4FMD7@85023,COG2378@1,COG2378@2 NA|NA|NA K Helicase conserved C-terminal domain MAG.T22.42_00349 1120959.ATXF01000007_gene2291 3.8e-256 890.6 Microbacteriaceae ercc3 3.6.4.12 ko:K10843 ko03022,ko03420,map03022,map03420 M00290 ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2GIR9@201174,4FMYM@85023,COG1061@1,COG1061@2 NA|NA|NA L ERCC3/RAD25/XPB C-terminal helicase MAG.T22.42_00350 1121924.ATWH01000010_gene1012 4.2e-116 424.1 Microbacteriaceae Bacteria 2GIZB@201174,4FKUS@85023,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal MAG.T22.42_00351 1120959.ATXF01000007_gene2284 2.6e-152 545.4 Microbacteriaceae phoR 2.7.13.3 ko:K02484,ko:K07768 ko02020,map02020 M00443 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2I2DU@201174,4FTMW@85023,COG5002@1,COG5002@2 NA|NA|NA T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain MAG.T22.42_00352 1120960.ATXG01000016_gene1514 1.7e-18 98.6 Microbacteriaceae Bacteria 2GQI8@201174,4FQ79@85023,COG4842@1,COG4842@2 NA|NA|NA S Proteins of 100 residues with WXG MAG.T22.42_00353 1416759.AYMR01000009_gene2878 1e-85 323.6 Microbacteriaceae Bacteria 2GKED@201174,4FMET@85023,COG0179@1,COG0179@2 NA|NA|NA Q Fumarylacetoacetate (FAA) hydrolase family MAG.T22.42_00354 1380347.JNII01000005_gene3327 1.5e-13 82.8 Actinobacteria Bacteria 2GNKU@201174,COG0657@1,COG0657@2 NA|NA|NA I Alpha beta hydrolase MAG.T22.42_00355 1380347.JNII01000005_gene3272 7.9e-26 123.6 Frankiales Bacteria 2GNKU@201174,4EVK1@85013,COG0657@1,COG0657@2 NA|NA|NA I Carboxylesterase family MAG.T22.42_00356 314271.RB2654_20373 1.4e-29 136.7 Alphaproteobacteria Bacteria 1NN2Y@1224,2FFKQ@1,2UMJD@28211,347I4@2 NA|NA|NA S SnoaL-like domain MAG.T22.42_00357 1404245.CGLY_00410 1e-51 209.5 Actinobacteria ko:K14250 ko00253,ko01057,ko01130,map00253,map01057,map01130 M00778 R09188,R09325,R09326,R09350 RC02459,RC02512,RC02517 ko00000,ko00001,ko00002 Bacteria 2ICNS@201174,COG1878@1,COG1878@2 NA|NA|NA S Putative cyclase MAG.T22.42_00358 1120959.ATXF01000007_gene2282 9.4e-268 929.1 Microbacteriaceae groL GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016465,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032991,GO:0036293,GO:0040007,GO:0042026,GO:0042603,GO:0043388,GO:0044093,GO:0044183,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051704,GO:0061077,GO:0065007,GO:0065009,GO:0070482,GO:0071944,GO:0101031,GO:1990220,GO:2000677,GO:2000679 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 2GKC9@201174,4FKRV@85023,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions MAG.T22.42_00359 1120959.ATXF01000007_gene2281 6.6e-91 340.9 Microbacteriaceae yerB Bacteria 2GP8D@201174,4FNB2@85023,COG1470@1,COG1470@2 NA|NA|NA S Protein of unknown function (DUF3048) C-terminal domain MAG.T22.42_00360 1150399.AQYK01000002_gene2785 5.9e-25 120.9 Microbacteriaceae Bacteria 2I7ZQ@201174,4FTUS@85023,COG1316@1,COG1316@2 NA|NA|NA K LytR cell envelope-related transcriptional attenuator MAG.T22.42_00361 1120959.ATXF01000007_gene2274 5.2e-74 284.6 Microbacteriaceae Bacteria 2GKH8@201174,4FMIF@85023,COG1651@1,COG1651@2 NA|NA|NA O Thioredoxin MAG.T22.42_00363 1120960.ATXG01000016_gene1526 8.5e-142 510.0 Microbacteriaceae rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 ko00000,ko01000,ko03009 Bacteria 2GJMR@201174,4FK9D@85023,COG0566@1,COG0566@2 NA|NA|NA J RNA 2'-O ribose methyltransferase substrate binding MAG.T22.42_00364 1120960.ATXG01000016_gene1527 5e-177 627.5 Microbacteriaceae cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJF2@201174,4FK3Z@85023,COG0215@1,COG0215@2 NA|NA|NA J cysteine-tRNA ligase activity MAG.T22.42_00365 1121372.AULK01000005_gene1614 4.2e-92 345.1 Microbacteriaceae ispF GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0008685,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0016829,GO:0016849,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.405,2.1.1.228,2.7.7.40,2.7.7.60,4.6.1.12 ko:K00554,ko:K00991,ko:K01770,ko:K12506,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 M00096 R00597,R01525,R02921,R05633,R05637 RC00002,RC00003,RC00089,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 iNJ661.Rv3581c Bacteria 2II8H@201174,4FKMA@85023,COG0245@1,COG0245@2,COG1211@1,COG1211@2 NA|NA|NA I Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) MAG.T22.42_00366 1121952.ATXT01000015_gene48 3.6e-74 284.3 Microbacteriaceae carD GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 ko:K07736 ko00000,ko03000 Bacteria 2GKSU@201174,4FNEK@85023,COG1329@1,COG1329@2 NA|NA|NA K CarD-like/TRCF domain MAG.T22.42_00367 1121924.ATWH01000010_gene990 2e-19 102.4 Microbacteriaceae Bacteria 2E56G@1,2IQ4V@201174,32ZZ6@2,4FPQR@85023 NA|NA|NA MAG.T22.42_00368 1389489.O159_06490 7.9e-91 340.1 Microbacteriaceae Bacteria 2GKFS@201174,4FKR2@85023,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal MAG.T22.42_00369 1120960.ATXG01000016_gene1532 6.3e-101 374.4 Microbacteriaceae senX3 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 ko:K07636,ko:K07768,ko:K11383 ko02020,map02020 M00434,M00443,M00505 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2GJY7@201174,4FK7K@85023,COG5002@1,COG5002@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain MAG.T22.42_00370 1150399.AQYK01000002_gene2829 3.2e-81 308.1 Microbacteriaceae phoU ko:K02039 ko00000 Bacteria 2GKAD@201174,4FMJB@85023,COG0704@1,COG0704@2 NA|NA|NA P Plays a role in the regulation of phosphate uptake MAG.T22.42_00371 1001240.GY21_02185 1.5e-111 409.1 Microbacteriaceae gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2GK8F@201174,4FM13@85023,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate MAG.T22.42_00372 1177594.MIC448_810040 1.2e-58 233.8 Microbacteriaceae Bacteria 2GIR7@201174,4FMXA@85023,COG4129@1,COG4129@2 NA|NA|NA S membrane MAG.T22.42_00373 1120960.ATXG01000014_gene479 3.6e-90 338.6 Microbacteriaceae ygfZ GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0051186,GO:0071840 2.1.2.10 ko:K00605,ko:K06980 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 2GKP0@201174,4FKWF@85023,COG0354@1,COG0354@2 NA|NA|NA S Aminomethyltransferase folate-binding domain MAG.T22.42_00376 1120960.ATXG01000014_gene483 4.4e-86 324.3 Microbacteriaceae Bacteria 2GJGU@201174,4FKR6@85023,COG0745@1,COG0745@2 NA|NA|NA KT Transcriptional regulatory protein, C terminal MAG.T22.42_00377 1120960.ATXG01000014_gene486 3.7e-304 1050.4 Microbacteriaceae ppk 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2GJ0B@201174,4FKIS@85023,COG0855@1,COG0855@2 NA|NA|NA P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) MAG.T22.42_00378 1120960.ATXG01000014_gene487 5.3e-114 417.5 Microbacteriaceae mutT 3.6.1.55 ko:K03574,ko:K08296 ko00000,ko01000,ko03400 Bacteria 2I2N2@201174,4FMSI@85023,COG1051@1,COG1051@2,COG2062@1,COG2062@2 NA|NA|NA FT Phosphoglycerate mutase family MAG.T22.42_00379 1120960.ATXG01000014_gene492 2.7e-119 434.9 Microbacteriaceae pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 Bacteria 2GJQ3@201174,4FK4A@85023,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system MAG.T22.42_00380 1001240.GY21_02130 7.5e-104 383.6 Microbacteriaceae pstA GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 ko:K02037,ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 iJN746.PP_2658,iPC815.YPO4115,iYL1228.KPN_04131,iZ_1308.Z5217 Bacteria 2I2F2@201174,4FKZZ@85023,COG0581@1,COG0581@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component MAG.T22.42_00381 1001240.GY21_02135 4.5e-108 397.9 Microbacteriaceae pstC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0009314,GO:0009628,GO:0010921,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 ko:K02037,ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 iAF987.Gmet_2702,ic_1306.c4652 Bacteria 2GJDA@201174,4FKAD@85023,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane MAG.T22.42_00382 1001240.GY21_02140 1e-95 357.1 Microbacteriaceae pstS ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 2GJXD@201174,4FKUY@85023,COG0226@1,COG0226@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import MAG.T22.42_00383 1120960.ATXG01000014_gene493 3e-106 391.7 Microbacteriaceae pabC 2.6.1.42,4.1.3.38 ko:K00826,ko:K02619 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R05553,R10991 RC00006,RC00036,RC01843,RC02148 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GN5Z@201174,4FK6S@85023,COG0115@1,COG0115@2 NA|NA|NA EH Amino-transferase class IV MAG.T22.42_00384 1246995.AFR_22960 7.4e-173 617.5 Micromonosporales 2.7.11.1,3.2.1.4 ko:K01179,ko:K12567 ko00500,ko01100,ko05410,ko05414,map00500,map01100,map05410,map05414 R06200,R11307,R11308 ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812 GH5,GH9 Bacteria 2H7QD@201174,4DJZF@85008,COG4733@1,COG4733@2 NA|NA|NA NU Fibronectin type III domain MAG.T22.42_00385 1206101.AZXC01000008_gene3081 1.1e-09 70.1 Actinobacteria Bacteria 2ES0Y@1,2IISE@201174,33JK0@2 NA|NA|NA MAG.T22.42_00386 1120958.AULD01000007_gene966 6.6e-15 86.7 Microbacteriaceae GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008150,GO:0040008,GO:0045926,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0065007,GO:0097159,GO:1901363 Bacteria 2GWEG@201174,4FQNJ@85023,COG0864@1,COG0864@2 NA|NA|NA K Transcriptional regulator MAG.T22.42_00387 1120958.AULD01000007_gene965 3.1e-43 181.0 Microbacteriaceae ko:K07171 ko00000,ko01000,ko02048 Bacteria 2HSQI@201174,4FPW5@85023,COG2337@1,COG2337@2 NA|NA|NA T PemK-like, MazF-like toxin of type II toxin-antitoxin system MAG.T22.42_00388 1121924.ATWH01000010_gene972 3.9e-61 241.5 Microbacteriaceae Bacteria 28MMU@1,2HAD5@201174,2ZAXG@2,4FMEH@85023 NA|NA|NA MAG.T22.42_00389 1449058.JQKT01000007_gene876 5.7e-62 245.4 Microbacteriaceae Bacteria 2GU7G@201174,4FKU4@85023,COG1403@1,COG1403@2 NA|NA|NA V Domain of unknown function (DUF222) MAG.T22.42_00390 1120959.ATXF01000007_gene2230 2.9e-47 194.9 Microbacteriaceae ybaK_1 3.4.15.5 ko:K01284 ko00000,ko01000,ko01002 Bacteria 2IKUX@201174,4FNY7@85023,COG2606@1,COG2606@2 NA|NA|NA S Aminoacyl-tRNA editing domain MAG.T22.42_00391 670487.Ocepr_2122 4.6e-29 134.8 Bacteria yhjR 2.7.7.87 ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria COG4902@1,COG4902@2 NA|NA|NA MAG.T22.42_00397 1121934.AUDX01000018_gene759 8.8e-80 304.3 Microbacteriaceae intA Bacteria 2HGQK@201174,4FS68@85023,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase family MAG.T22.42_00398 1283287.KB822575_gene247 6.3e-211 740.3 Propionibacteriales treA 3.2.1.10,3.2.1.20,3.2.1.93 ko:K01182,ko:K01187,ko:K01226 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R00837,R01718,R01791,R06087,R06088,R06113,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 2GKS4@201174,4DP3G@85009,COG0366@1,COG0366@2 NA|NA|NA G Alpha-amylase domain MAG.T22.42_00399 443218.AS9A_1719 5.1e-56 224.9 Actinobacteria 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 GH32 Bacteria 2H3S0@201174,COG1621@1,COG1621@2 NA|NA|NA G Glycosyl hydrolase family 32 MAG.T22.42_00400 1122919.KB905564_gene2578 6.7e-76 290.8 Paenibacillaceae ko:K10119 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 1TR45@1239,26TKZ@186822,4HCEH@91061,COG0395@1,COG0395@2 NA|NA|NA G Sugar ABC transporter permease MAG.T22.42_00401 529884.Rhola_00013110 3.9e-95 354.8 Microbacteriaceae ko:K10118,ko:K10228,ko:K15771 ko02010,map02010 M00196,M00200,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2,3.A.1.1.28,3.A.1.1.5 Bacteria 2GKJI@201174,4FN7Z@85023,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component MAG.T22.42_00402 529884.Rhola_00013120 5.7e-114 417.9 Microbacteriaceae ko:K10117 ko02010,map02010 M00196 ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 Bacteria 2I3BP@201174,4FMPY@85023,COG1653@1,COG1653@2 NA|NA|NA G Extracellular solute-binding protein MAG.T22.42_00403 1132441.KI519455_gene3021 2.2e-68 266.2 Actinobacteria Bacteria 2H9BV@201174,COG1609@1,COG1609@2 NA|NA|NA K transcriptional regulator MAG.T22.42_00404 1122239.AULS01000012_gene1056 1.7e-148 532.3 Microbacteriaceae ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko02000 3.A.1.1 Bacteria 2GJCM@201174,4FKGH@85023,COG3842@1,COG3842@2 NA|NA|NA E Belongs to the ABC transporter superfamily MAG.T22.42_00405 1389489.O159_19590 9.8e-58 229.9 Actinobacteria lidJ ko:K03611 ko00000,ko03110 5.A.2.1 Bacteria 2IIE7@201174,COG1495@1,COG1495@2 NA|NA|NA O Disulfide bond formation protein DsbB MAG.T22.42_00406 1122237.AUGQ01000005_gene1412 3.5e-128 464.5 Microbacteriaceae folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJZS@201174,4FKNP@85023,COG0190@1,COG0190@2 NA|NA|NA H Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate MAG.T22.42_00407 979556.MTES_0683 3e-216 757.7 Microbacteriaceae glyA GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009069,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019752,GO:0019842,GO:0020012,GO:0030170,GO:0030312,GO:0030682,GO:0036094,GO:0042133,GO:0042783,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044464,GO:0046983,GO:0048037,GO:0050662,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0071944,GO:0075136,GO:0097159,GO:1901363,GO:1901564,GO:1901605 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK7U@201174,4FKF4@85023,COG0112@1,COG0112@2 NA|NA|NA E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism MAG.T22.42_00408 1416759.AYMR01000007_gene890 6.1e-133 480.3 Microbacteriaceae purU 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 R00944 RC00026,RC00111 ko00000,ko00001,ko01000 Bacteria 2GM0G@201174,4FKMK@85023,COG0788@1,COG0788@2 NA|NA|NA F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) MAG.T22.42_00410 1120960.ATXG01000014_gene530 6.4e-24 117.1 Microbacteriaceae Bacteria 2EJFD@1,2ISPH@201174,33D6D@2,4FTJF@85023 NA|NA|NA S Protein of unknown function (DUF2568) MAG.T22.42_00411 1120960.ATXG01000014_gene539 9.9e-58 229.6 Microbacteriaceae 2.3.1.57 ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 M00135 R01154 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 2I3WT@201174,4FTKZ@85023,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) family MAG.T22.42_00412 1001240.GY21_14130 3.1e-29 134.4 Microbacteriaceae ybaZ GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 ko:K00567,ko:K07443 ko00000,ko01000,ko03400 Bacteria 2GQMD@201174,4FPZ4@85023,COG3695@1,COG3695@2 NA|NA|NA L 6-O-methylguanine DNA methyltransferase, DNA binding domain MAG.T22.42_00413 1121372.AULK01000005_gene1674 9.4e-208 729.9 Microbacteriaceae ndvA ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4FMKN@85023,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region MAG.T22.42_00414 1150399.AQYK01000002_gene2915 2e-186 659.1 Microbacteriaceae ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4FKMN@85023,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region MAG.T22.42_00415 1120960.ATXG01000010_gene2680 7.6e-152 543.5 Microbacteriaceae add GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 ko:K01488 ko00230,ko01100,ko05340,map00230,map01100,map05340 R01560,R02556 RC00477 ko00000,ko00001,ko01000 Bacteria 2GJ6I@201174,4FMEJ@85023,COG1816@1,COG1816@2 NA|NA|NA F Adenosine/AMP deaminase MAG.T22.42_00416 1120959.ATXF01000004_gene2922 9.4e-197 693.0 Microbacteriaceae deoA 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 Bacteria 2GJH5@201174,4FM1N@85023,COG0213@1,COG0213@2 NA|NA|NA F Pyrimidine nucleoside phosphorylase C-terminal domain MAG.T22.42_00417 1416759.AYMR01000001_gene1658 1.3e-56 225.7 Microbacteriaceae cdd 2.4.2.4,3.5.4.5 ko:K00758,ko:K01489 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R01878,R02484,R02485,R08221,R08222,R08230 RC00063,RC00074,RC00514 ko00000,ko00001,ko01000 Bacteria 2IHP7@201174,4FNQU@85023,COG0295@1,COG0295@2 NA|NA|NA F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis MAG.T22.42_00418 979556.MTES_0619 4e-152 544.7 Microbacteriaceae ko:K02057 M00221 ko00000,ko00002,ko02000 3.A.1.2 Bacteria 2GKMB@201174,4FMFE@85023,COG1079@1,COG1079@2 NA|NA|NA S Belongs to the binding-protein-dependent transport system permease family MAG.T22.42_00419 1120959.ATXF01000004_gene2919 4.8e-163 580.9 Microbacteriaceae ko:K02057 M00221 ko00000,ko00002,ko02000 3.A.1.2 Bacteria 2GKAZ@201174,4FM7C@85023,COG4603@1,COG4603@2 NA|NA|NA S Belongs to the binding-protein-dependent transport system permease family MAG.T22.42_00420 1120959.ATXF01000004_gene2918 4.4e-219 767.3 Microbacteriaceae rbsA 3.6.3.17 ko:K02056 M00221 ko00000,ko00002,ko01000,ko02000 3.A.1.2 Bacteria 2H7KJ@201174,4FKR5@85023,COG3845@1,COG3845@2 NA|NA|NA S ATPases associated with a variety of cellular activities MAG.T22.42_00421 1120960.ATXG01000010_gene2686 2e-128 465.7 Microbacteriaceae ko:K07335 ko00000 Bacteria 2GMFS@201174,4FMK6@85023,COG1744@1,COG1744@2 NA|NA|NA S ABC transporter substrate-binding protein PnrA-like MAG.T22.42_00422 1120959.ATXF01000004_gene2915 9.6e-158 563.1 Microbacteriaceae manC 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIRM@201174,4FKD9@85023,COG0836@1,COG0836@2 NA|NA|NA M Mannose-6-phosphate isomerase MAG.T22.42_00423 1120959.ATXF01000004_gene2914 4.6e-49 200.7 Microbacteriaceae sdhC ko:K00241,ko:K00247 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 Bacteria 2IKU7@201174,4FP54@85023,COG2009@1,COG2009@2 NA|NA|NA C Succinate dehydrogenase/Fumarate reductase transmembrane subunit MAG.T22.42_00424 1001240.GY21_11800 3.8e-51 207.6 Microbacteriaceae sdhD ko:K00242,ko:K00246 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00149,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002 Bacteria 2GNKE@201174,4FNS6@85023,COG2142@1,COG2142@2 NA|NA|NA C Succinate dehydrogenase/Fumarate reductase transmembrane subunit MAG.T22.42_00425 1120960.ATXG01000010_gene2691 0.0 1085.1 Microbacteriaceae sdhA GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071704,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0072350,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_0603,iJN746.PP_4191,iPC815.YPO1111 Bacteria 2GJ45@201174,4FKH0@85023,COG1053@1,COG1053@2 NA|NA|NA C Fumarate reductase flavoprotein C-term MAG.T22.42_00426 1120959.ATXF01000004_gene2911 8.3e-126 456.4 Microbacteriaceae sdhB GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0022904,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 e_coli_core.b0724,iAF1260.b0724,iBWG_1329.BWG_0583,iEC042_1314.EC042_0742,iECDH10B_1368.ECDH10B_0791,iECDH1ME8569_1439.ECDH1ME8569_0683,iECUMN_1333.ECUMN_0802,iEcDH1_1363.EcDH1_2911,iJO1366.b0724,iJR904.b0724,iY75_1357.Y75_RS03765 Bacteria 2GP9C@201174,4FK5B@85023,COG0479@1,COG0479@2 NA|NA|NA C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family MAG.T22.42_00429 1120958.AULD01000015_gene1362 8.9e-220 769.6 Microbacteriaceae glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 Bacteria 2GM13@201174,4FKW2@85023,COG0554@1,COG0554@2 NA|NA|NA C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate MAG.T22.42_00430 1122175.ATXU01000004_gene2374 5.7e-199 700.7 Microbacteriaceae glpD 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 R00848 RC00029 ko00000,ko00001,ko01000 Bacteria 2GJKN@201174,4FKEP@85023,COG0578@1,COG0578@2 NA|NA|NA C C-terminal domain of alpha-glycerophosphate oxidase MAG.T22.42_00431 443906.CMM_0968 1.8e-186 659.1 Microbacteriaceae ptsI 2.7.3.9 ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 8.A.7 Bacteria 2GIZZ@201174,4FKFR@85023,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) MAG.T22.42_00432 1123052.AUDF01000005_gene1045 5.9e-87 327.4 Microbacteriaceae ko:K02081,ko:K03436 ko00000,ko03000 Bacteria 2GKWM@201174,4FP9F@85023,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain MAG.T22.42_00433 1237500.ANBA01000005_gene2700 7.9e-68 264.2 Streptosporangiales fruK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006000,GO:0006001,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0008662,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019318,GO:0019320,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0071704,GO:1901575 2.7.1.11,2.7.1.56 ko:K00882,ko:K16370 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00345 R00756,R02071,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iAF1260.b2168,iAPECO1_1312.APECO1_4386,iB21_1397.B21_02056,iEC042_1314.EC042_2401,iEC55989_1330.EC55989_2421,iECABU_c1320.ECABU_c24990,iECBD_1354.ECBD_1490,iECB_1328.ECB_02097,iECDH10B_1368.ECDH10B_2325,iECDH1ME8569_1439.ECDH1ME8569_2104,iECD_1391.ECD_02097,iECED1_1282.ECED1_2616,iECH74115_1262.ECH74115_3304,iECIAI1_1343.ECIAI1_2248,iECIAI39_1322.ECIAI39_2308,iECNA114_1301.ECNA114_2259,iECO103_1326.ECO103_2643,iECO111_1330.ECO111_2886,iECO26_1355.ECO26_3080,iECOK1_1307.ECOK1_2400,iECP_1309.ECP_2208,iECS88_1305.ECS88_2316,iECSE_1348.ECSE_2436,iECSF_1327.ECSF_2049,iECSP_1301.ECSP_3046,iECUMN_1333.ECUMN_2504,iECW_1372.ECW_m2369,iECs_1301.ECs3060,iEKO11_1354.EKO11_1586,iETEC_1333.ETEC_2303,iEcDH1_1363.EcDH1_1490,iEcHS_1320.EcHS_A2305,iEcSMS35_1347.EcSMS35_2315,iEcolC_1368.EcolC_1480,iG2583_1286.G2583_2711,iJO1366.b2168,iJR904.b2168,iLF82_1304.LF82_0744,iNRG857_1313.NRG857_11005,iPC815.YPO1299,iSBO_1134.SBO_2156,iSDY_1059.SDY_2316,iSFV_1184.SFV_2243,iSF_1195.SF2253,iSFxv_1172.SFxv_2486,iS_1188.S2382,iUMN146_1321.UM146_05955,iUMNK88_1353.UMNK88_2713,iUTI89_1310.UTI89_C2443,iWFL_1372.ECW_m2369,iY75_1357.Y75_RS11345,iZ_1308.Z3426,ic_1306.c2703 Bacteria 2GK7E@201174,4EHTI@85012,COG1105@1,COG1105@2 NA|NA|NA G pfkB family carbohydrate kinase MAG.T22.42_00434 1089544.KB912942_gene146 9.6e-45 186.4 Pseudonocardiales fruA 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02806 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 Bacteria 2IMPP@201174,4E3T9@85010,COG1762@1,COG1762@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 MAG.T22.42_00435 529884.Rhola_00012900 6e-33 147.1 Actinobacteria frwB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090582 ko:K11202 M00306 ko00000,ko00002,ko01000,ko02000 4.A.2.1 Bacteria 2IPEN@201174,COG1445@1,COG1445@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit MAG.T22.42_00436 529884.Rhola_00012890 7.1e-105 387.5 Microbacteriaceae fruA 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 Bacteria 2GJU4@201174,4FKRE@85023,COG1299@1,COG1299@2 NA|NA|NA GT PTS system, Lactose/Cellobiose specific IIB subunit MAG.T22.42_00438 1120959.ATXF01000004_gene2906 4.3e-61 241.9 Microbacteriaceae ko:K07058 ko00000 Bacteria 2GN79@201174,4FMS7@85023,COG1295@1,COG1295@2 NA|NA|NA S Virulence factor BrkB MAG.T22.42_00439 1120959.ATXF01000004_gene2905 1.6e-122 445.7 Microbacteriaceae exoA 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKIS@201174,4FM4A@85023,COG0708@1,COG0708@2 NA|NA|NA L Endonuclease/Exonuclease/phosphatase family MAG.T22.42_00440 1397278.AYMV01000015_gene2205 8.5e-126 456.8 Microbacteriaceae trpS GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJ9A@201174,4FKF2@85023,COG0180@1,COG0180@2 NA|NA|NA J tRNA synthetases class I (W and Y) MAG.T22.42_00441 1115632.JAFW01000001_gene2113 5.4e-127 461.5 Actinobacteria Bacteria 2GITS@201174,COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T22.42_00442 1120960.ATXG01000028_gene2705 6.4e-108 397.5 Microbacteriaceae ribD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008703,GO:0008835,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016020,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0034641,GO:0036094,GO:0040007,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.193,3.5.4.26 ko:K01498,ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1624,iB21_1397.B21_00366,iECBD_1354.ECBD_3247,iECB_1328.ECB_00362,iECD_1391.ECD_00362,iECED1_1282.ECED1_0437,iECNA114_1301.ECNA114_0391,iECSF_1327.ECSF_0374,iEcolC_1368.EcolC_3219,iJN746.PP_0514,iLF82_1304.LF82_1880,iLJ478.TM1828,iNRG857_1313.NRG857_01945,iYL1228.KPN_00366,ic_1306.c0524 Bacteria 2GKAX@201174,4FKJG@85023,COG0117@1,COG0117@2,COG1985@1,COG1985@2 NA|NA|NA H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate MAG.T22.42_00443 273677.BW34_02439 4.3e-73 281.2 Microbacteriaceae ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9,3.5.4.25,4.1.99.12 ko:K00793,ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00066,R00425,R07281 RC00293,RC00958,RC00960,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS08950 Bacteria 2GKC5@201174,4FNHN@85023,COG0307@1,COG0307@2 NA|NA|NA H Lumazine binding domain MAG.T22.42_00444 1121952.ATXT01000017_gene791 2.8e-166 591.7 Microbacteriaceae ribA 3.5.4.25,4.1.99.12 ko:K01497,ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWJ@201174,4FKK7@85023,COG0108@1,COG0108@2,COG0807@1,COG0807@2 NA|NA|NA H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate MAG.T22.42_00445 1451261.AS96_11290 7.9e-58 229.9 Microbacteriaceae ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 Bacteria 2II1Z@201174,4FNJZ@85023,COG0054@1,COG0054@2 NA|NA|NA H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin MAG.T22.42_00446 1150399.AQYK01000001_gene1019 8.9e-32 143.3 Microbacteriaceae Bacteria 2DUHZ@1,2IPWV@201174,32UXA@2,4FP36@85023 NA|NA|NA S Predicted integral membrane protein (DUF2269) MAG.T22.42_00447 1449058.JQKT01000010_gene2140 1.5e-189 669.5 Microbacteriaceae ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GJTA@201174,4FM09@85023,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region MAG.T22.42_00448 1120960.ATXG01000013_gene3525 6e-295 1019.6 Microbacteriaceae pckG GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007028,GO:0007154,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009267,GO:0009410,GO:0009605,GO:0009607,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010106,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016020,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019725,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030003,GO:0030145,GO:0030154,GO:0030312,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031668,GO:0031669,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033554,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042592,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0046916,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0048878,GO:0050789,GO:0050792,GO:0050794,GO:0050801,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0065008,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071496,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0071944,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0075136,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:0098771,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32,4.1.1.49 ko:K01596,ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 M00003,M00170 R00341,R00431,R00726 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2638 Bacteria 2GJH3@201174,4FMII@85023,COG1274@1,COG1274@2 NA|NA|NA C Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle MAG.T22.42_00449 1120960.ATXG01000013_gene3524 4.8e-215 753.8 Microbacteriaceae hipB ko:K07110 ko00000,ko03000 Bacteria 2GMWU@201174,4FMWH@85023,COG1396@1,COG1396@2,COG3800@1,COG3800@2 NA|NA|NA K Helix-turn-helix domain MAG.T22.42_00450 1150398.JIBJ01000004_gene2753 4.9e-71 274.2 Micrococcaceae Z012_01630 Bacteria 1WAGZ@1268,2GJQ7@201174,COG0656@1,COG0656@2 NA|NA|NA S Aldo/keto reductase family MAG.T22.42_00451 1298860.AUEM01000001_gene1323 1.2e-78 299.7 Microbacteriaceae Bacteria 2GJS3@201174,4FNKA@85023,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix domain MAG.T22.42_00452 399741.Spro_4104 4e-13 80.5 Serratia Bacteria 1PVUB@1224,1TKAQ@1236,2AP8C@1,31EA8@2,4058F@613 NA|NA|NA S Domain of unknown function (DUF4160) MAG.T22.42_00453 518766.Rmar_2432 3.9e-13 80.5 Bacteroidetes Bacteria 2A1D2@1,30PK3@2,4NW4I@976 NA|NA|NA S Protein of unknown function (DUF2442) MAG.T22.42_00454 1120959.ATXF01000011_gene294 1.4e-18 99.0 Actinobacteria Bacteria 2DU7V@1,2GYS2@201174,33P9F@2 NA|NA|NA MAG.T22.42_00455 1370125.AUWT01000055_gene897 4.6e-175 620.9 Mycobacteriaceae gabD1 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009013,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 235T4@1762,2GIWZ@201174,COG1012@1,COG1012@2 NA|NA|NA C Catalyzes the NADP( )-dependent oxidation of succinate semialdehyde to succinate. It is believed to be the main source of succinate semialdehyde dehydrogenase activity in Mycobacterium MAG.T22.42_00456 1237500.ANBA01000009_gene1268 2.8e-09 67.8 Streptosporangiales Bacteria 2DNUV@1,2GSRG@201174,32Z9W@2,4EJXX@85012 NA|NA|NA S Protein of unknown function (DUF2470) MAG.T22.42_00457 1150398.JIBJ01000003_gene1719 1.2e-253 882.5 Micrococcaceae 6.2.1.1,6.2.1.16 ko:K01895,ko:K01907 ko00010,ko00280,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00280,map00620,map00640,map00650,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354,R01357 RC00004,RC00012,RC00014,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1W8AD@1268,2GM20@201174,COG0365@1,COG0365@2 NA|NA|NA I Acetyl-coenzyme A synthetase N-terminus MAG.T22.42_00458 471857.Svir_26680 6.5e-42 177.6 Pseudonocardiales Bacteria 2I9CD@201174,4E2EZ@85010,COG1414@1,COG1414@2 NA|NA|NA K helix_turn_helix isocitrate lyase regulation MAG.T22.42_00461 1120966.AUBU01000013_gene510 4.5e-41 176.4 Bacteroidetes hxuA GO:0005575,GO:0005576 ko:K15125,ko:K20276 ko02024,ko05133,map02024,map05133 ko00000,ko00001,ko00536 Bacteria 4NUIW@976,COG2911@1,COG2911@2,COG2982@1,COG2982@2,COG3209@1,COG3209@2,COG3210@1,COG3210@2 NA|NA|NA M COG3209 Rhs family protein MAG.T22.42_00462 979556.MTES_3350 9.3e-37 160.2 Microbacteriaceae Bacteria 2GMVK@201174,4FNMW@85023,COG4243@1,COG4243@2 NA|NA|NA S VKc MAG.T22.42_00463 1048339.KB913029_gene5053 4.5e-07 62.0 Frankiales Bacteria 2GKS7@201174,4EX57@85013,COG2931@1,COG2931@2 NA|NA|NA Q Haemolysin-type calcium-binding repeat (2 copies) MAG.T22.42_00465 888050.HMPREF9004_1318 4.4e-10 69.3 Actinobacteria Bacteria 2DQRG@1,2GURK@201174,33894@2,4D6GE@85005 NA|NA|NA MAG.T22.42_00466 1219581.HMPREF1628_03470 2.1e-17 94.4 Actinobacteria Bacteria 2DQRG@1,2GURK@201174,33894@2,4D6GE@85005 NA|NA|NA MAG.T22.42_00467 1232429.CBLL010000098_gene730 4.3e-22 110.5 Micrococcaceae csoR ko:K21600 ko00000,ko03000 Bacteria 1WA2B@1268,2IQ7U@201174,COG1937@1,COG1937@2 NA|NA|NA S Metal-sensitive transcriptional repressor MAG.T22.42_00468 1449058.JQKT01000009_gene143 6e-198 697.2 Microbacteriaceae cdr ko:K04085 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Bacteria 2H7WY@201174,4FKDZ@85023,COG0446@1,COG0446@2,COG0607@1,COG0607@2 NA|NA|NA P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain MAG.T22.42_00469 1120959.ATXF01000008_gene425 1.9e-238 831.6 Microbacteriaceae der GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 ko:K00058,ko:K03977 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 2GJ8J@201174,4FKKY@85023,COG1160@1,COG1160@2 NA|NA|NA S GTPase that plays an essential role in the late steps of ribosome biogenesis MAG.T22.42_00470 1123052.AUDF01000009_gene1644 2.1e-51 209.1 Microbacteriaceae cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945,ko:K03977 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2H3SI@201174,4FNIG@85023,COG0283@1,COG0283@2 NA|NA|NA F Cytidylate kinase MAG.T22.42_00471 1120959.ATXF01000008_gene423 5.3e-113 414.5 Microbacteriaceae tyrA 1.3.1.12,1.3.1.43 ko:K00210,ko:K00220,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025,M00040 R00732,R01728 RC00125 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKB4@201174,4FMQ4@85023,COG0287@1,COG0287@2 NA|NA|NA E Prephenate dehydrogenase MAG.T22.42_00472 1120959.ATXF01000008_gene422 5.8e-88 330.9 Microbacteriaceae rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 ko00000,ko01000,ko03009 Bacteria 2GJ4N@201174,4FK4E@85023,COG1187@1,COG1187@2 NA|NA|NA J RNA pseudouridylate synthase MAG.T22.42_00473 1120960.ATXG01000023_gene3842 9.4e-59 233.4 Microbacteriaceae scpB ko:K06024 ko00000,ko03036 Bacteria 2GISY@201174,4FNCB@85023,COG1386@1,COG1386@2 NA|NA|NA K Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves MAG.T22.42_00474 1150399.AQYK01000001_gene1227 6.8e-113 413.7 Microbacteriaceae scpA ko:K05896 ko00000,ko03036 Bacteria 2GN1U@201174,4FMBB@85023,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves MAG.T22.42_00475 1416759.AYMR01000001_gene1491 1e-108 399.8 Microbacteriaceae soj GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 ko:K03496 ko00000,ko03036,ko04812 Bacteria 2GJX3@201174,4FKN6@85023,COG1192@1,COG1192@2 NA|NA|NA D Cellulose biosynthesis protein BcsQ MAG.T22.42_00476 1177594.MIC448_1330010 1.3e-99 369.8 Actinobacteria yedA Bacteria 2I8X5@201174,COG0697@1,COG0697@2 NA|NA|NA EG of the drug metabolite transporter (DMT) superfamily MAG.T22.42_00477 1416759.AYMR01000001_gene1492 2e-95 355.9 Microbacteriaceae xerD GO:0008150,GO:0040007 ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 2GNDP@201174,4FMIB@85023,COG4974@1,COG4974@2 NA|NA|NA L Phage integrase, N-terminal SAM-like domain MAG.T22.42_00478 1120960.ATXG01000023_gene3838 1.4e-60 239.6 Microbacteriaceae nudF 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 Bacteria 2GNW6@201174,4FNIB@85023,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain MAG.T22.42_00479 1177594.MIC448_2500029 2.5e-263 914.4 Microbacteriaceae pyrG GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iHN637.CLJU_RS01075,iNJ661.Rv1699,iPC815.YPO3377 Bacteria 2GJ13@201174,4FMWP@85023,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates MAG.T22.42_00480 1151122.AQYD01000005_gene2886 4.8e-161 574.7 Microbacteriaceae recN GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0030312,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 ko:K03631,ko:K13582 ko04112,map04112 ko00000,ko00001,ko03400 Bacteria 2GIVG@201174,4FKSG@85023,COG0497@1,COG0497@2 NA|NA|NA L May be involved in recombinational repair of damaged DNA MAG.T22.42_00481 1001240.GY21_20430 1.1e-92 346.7 Microbacteriaceae nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 2GKM2@201174,4FKIT@85023,COG0061@1,COG0061@2 NA|NA|NA G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP MAG.T22.42_00482 1120960.ATXG01000023_gene3834 7e-83 313.9 Microbacteriaceae tlyA GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 ko:K06442 ko00000,ko01000,ko03009 Bacteria 2GJVT@201174,4FKDV@85023,COG1189@1,COG1189@2 NA|NA|NA J FtsJ-like methyltransferase MAG.T22.42_00484 35754.JNYJ01000023_gene8238 2.2e-130 472.2 Micromonosporales argE 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 Bacteria 2I9GD@201174,4DCBI@85008,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain MAG.T22.42_00485 1122239.AULS01000019_gene275 3.6e-59 234.2 Microbacteriaceae msrB 1.8.4.12 ko:K07305 ko00000,ko01000 Bacteria 2IHV0@201174,4FNQ7@85023,COG0229@1,COG0229@2 NA|NA|NA O SelR domain MAG.T22.42_00486 1110697.NCAST_34_01220 8.5e-44 183.7 Nocardiaceae lysE GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 ko:K06895 ko00000,ko02000 2.A.75.1 Bacteria 2IHQ2@201174,4FZH1@85025,COG1279@1,COG1279@2 NA|NA|NA S LysE type translocator MAG.T22.42_00487 1121372.AULK01000001_gene2410 4e-55 221.9 Microbacteriaceae iciA GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003700,GO:0005488,GO:0006275,GO:0006355,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0043565,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K05596 ko00000,ko03000,ko03036 Bacteria 2GJEC@201174,4FNCE@85023,COG0583@1,COG0583@2 NA|NA|NA K Bacterial regulatory helix-turn-helix protein, lysR family MAG.T22.42_00488 1150399.AQYK01000001_gene277 4.5e-103 381.3 Microbacteriaceae 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 R03024 RC00151 ko00000,ko00001,ko01000 Bacteria 2GK7V@201174,4FKYY@85023,COG0647@1,COG0647@2 NA|NA|NA G Haloacid dehalogenase-like hydrolase MAG.T22.42_00489 1120960.ATXG01000023_gene3831 1e-75 290.8 Microbacteriaceae Bacteria 2GKX5@201174,4FK4D@85023,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.42_00492 1121372.AULK01000004_gene1309 3e-225 787.7 Microbacteriaceae argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 iSBO_1134.SBO_3210,iSbBS512_1146.SbBS512_E3599 Bacteria 2GK96@201174,4FMMU@85023,COG0137@1,COG0137@2 NA|NA|NA E Belongs to the argininosuccinate synthase family. Type MAG.T22.42_00493 1121952.ATXT01000013_gene2348 8e-100 370.5 Microbacteriaceae lipA Bacteria 2HXWT@201174,4FMIM@85023,COG0657@1,COG0657@2 NA|NA|NA I Carboxylesterase family MAG.T22.42_00494 76636.JOEC01000002_gene1937 7.2e-91 340.1 Microbacteriaceae spoU 2.1.1.185 ko:K03218 ko00000,ko01000,ko03009 Bacteria 2GM1A@201174,4FKEC@85023,COG0566@1,COG0566@2 NA|NA|NA J SpoU rRNA Methylase family MAG.T22.42_00495 1121924.ATWH01000023_gene3239 4.2e-140 504.6 Microbacteriaceae mntH GO:0000041,GO:0003674,GO:0005215,GO:0005384,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015075,GO:0015077,GO:0015078,GO:0015086,GO:0015291,GO:0015292,GO:0015293,GO:0015318,GO:0015672,GO:0015684,GO:0015691,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0034755,GO:0042221,GO:0044425,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070574,GO:0070838,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071421,GO:0071577,GO:0071578,GO:0071944,GO:0072511,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098739,GO:0099587,GO:1902600 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 iSF_1195.SF2457,iYO844.BSU04360 Bacteria 2GJSM@201174,4FKID@85023,COG1914@1,COG1914@2 NA|NA|NA P Natural resistance-associated macrophage protein MAG.T22.42_00496 1120959.ATXF01000005_gene1231 1.3e-42 180.3 Microbacteriaceae Bacteria 2DQKZ@1,2IHZZ@201174,337IN@2,4FP07@85023 NA|NA|NA MAG.T22.42_00497 1121372.AULK01000003_gene222 1.4e-77 295.8 Microbacteriaceae pyrE 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 iJN678.umpS Bacteria 2GKUQ@201174,4FKRQ@85023,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) MAG.T22.42_00498 281090.Lxx23390 1.3e-122 446.0 Microbacteriaceae xthA 3.1.11.2,6.5.1.1 ko:K01142,ko:K01971 ko03410,ko03450,map03410,map03450 R00381 RC00005 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKEW@201174,4FKCK@85023,COG0708@1,COG0708@2 NA|NA|NA L Endonuclease/Exonuclease/phosphatase family MAG.T22.42_00499 1151126.AQYI01000006_gene2935 9.6e-74 283.9 Microbacteriaceae hibch 1.1.1.31,3.1.2.4,4.2.1.17 ko:K00020,ko:K01692,ko:K05605 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212 M00013,M00032,M00087 R03026,R03045,R03158,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05064,R05066,R05595,R06411,R06412,R06942,R08093 RC00004,RC00014,RC00099,RC00137,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMET@201174,4FKVG@85023,COG1024@1,COG1024@2 NA|NA|NA I Enoyl-CoA hydratase/isomerase MAG.T22.42_00500 1151122.AQYD01000007_gene1019 1.8e-68 265.8 Microbacteriaceae ko:K05834 ko00000,ko02000 2.A.76.1.1 Bacteria 2GMDP@201174,4FM1T@85023,COG1280@1,COG1280@2 NA|NA|NA E LysE type translocator MAG.T22.42_00501 1150399.AQYK01000001_gene254 1e-31 142.9 Microbacteriaceae Bacteria 2EJYH@1,2IPQR@201174,33DP4@2,4FP78@85023 NA|NA|NA MAG.T22.42_00502 1120960.ATXG01000003_gene1858 4e-86 324.7 Microbacteriaceae hemD GO:0003674,GO:0003824,GO:0004852,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 ko:K01719,ko:K01749,ko:K02496,ko:K13542,ko:K13543 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084,R03165,R03194 RC00003,RC00871,RC01861,RC02317 ko00000,ko00001,ko00002,ko01000 iJN746.PP_0187,iSBO_1134.SBO_3815 Bacteria 2GMJZ@201174,4FMG2@85023,COG1587@1,COG1587@2 NA|NA|NA H Uroporphyrinogen-III synthase HemD MAG.T22.42_00505 1120960.ATXG01000003_gene1874 4.9e-21 107.5 Microbacteriaceae Bacteria 2DMMR@1,2IQA6@201174,32SHV@2,4FQ24@85023 NA|NA|NA S Putative Actinobacterial Holin-X, holin superfamily III MAG.T22.42_00506 1120960.ATXG01000003_gene1875 1.6e-14 85.9 Microbacteriaceae hemG Bacteria 2DRKZ@1,2GWR3@201174,33C8D@2,4FQB4@85023 NA|NA|NA MAG.T22.42_00507 1120960.ATXG01000003_gene1876 3.4e-34 152.9 Microbacteriaceae hemY 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMMA@201174,4FM75@85023,COG1232@1,COG1232@2 NA|NA|NA H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX MAG.T22.42_00508 1122175.ATXU01000007_gene162 4.9e-241 840.1 Microbacteriaceae glyQS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iSB619.SA_RS07880 Bacteria 2GIT3@201174,4FKDW@85023,COG0423@1,COG0423@2 NA|NA|NA J Catalyzes the attachment of glycine to tRNA(Gly) MAG.T22.42_00509 1121924.ATWH01000024_gene1050 1.1e-286 992.3 Microbacteriaceae pepO 3.4.24.11,3.4.24.71 ko:K01389,ko:K01415,ko:K07386 ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Bacteria 2GNJY@201174,4FKIZ@85023,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 MAG.T22.42_00510 446469.Sked_10870 1.9e-38 165.2 Actinobacteria yccF Bacteria 2IKS5@201174,COG3304@1,COG3304@2 NA|NA|NA S membrane MAG.T22.42_00511 1121924.ATWH01000024_gene1046 1.5e-87 330.1 Microbacteriaceae Bacteria 2GRCY@201174,4FM20@85023,COG0738@1,COG0738@2 NA|NA|NA G Major Facilitator Superfamily MAG.T22.42_00512 1120959.ATXF01000005_gene1552 6.8e-94 350.1 Microbacteriaceae nucS ko:K07503 ko00000,ko01000 Bacteria 2GIYB@201174,4FKDY@85023,COG1637@1,COG1637@2 NA|NA|NA L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures MAG.T22.42_00513 1120959.ATXF01000005_gene1550 2.4e-15 88.6 Microbacteriaceae Bacteria 2AYIP@1,2GVD7@201174,31QNF@2,4FQ7P@85023 NA|NA|NA MAG.T22.42_00515 1120959.ATXF01000005_gene1505 9.7e-87 326.6 Microbacteriaceae fhaA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 ko:K02283 ko00000,ko02035,ko02044 Bacteria 2GNU2@201174,4FKVU@85023,COG1716@1,COG1716@2 NA|NA|NA T Protein of unknown function (DUF2662) MAG.T22.42_00516 1120960.ATXG01000003_gene2025 4.3e-46 191.0 Microbacteriaceae fhaB GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 Bacteria 2GKA7@201174,4FNUE@85023,COG1716@1,COG1716@2 NA|NA|NA T Forkhead associated domain MAG.T22.42_00517 1120960.ATXG01000003_gene2026 9.8e-140 503.4 Microbacteriaceae pstP 3.1.3.16 ko:K20074 ko00000,ko01000,ko01009 Bacteria 2GJ3M@201174,4FKJ0@85023,COG0631@1,COG0631@2 NA|NA|NA T Protein phosphatase 2C MAG.T22.42_00518 1121924.ATWH01000025_gene1347 1.2e-183 649.4 Microbacteriaceae rodA GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 ko:K03588,ko:K05364,ko:K05837 ko00550,ko04112,map00550,map04112 R04519 RC00005,RC00049 ko00000,ko00001,ko01011,ko02000,ko03036 2.A.103.1 Bacteria 2GJTI@201174,4FKMX@85023,COG0772@1,COG0772@2 NA|NA|NA D Cell cycle protein MAG.T22.42_00519 1120960.ATXG01000003_gene2028 4.8e-178 630.9 Microbacteriaceae pbpA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K05364 ko00550,map00550 R04519 RC00005,RC00049 ko00000,ko00001,ko01011 Bacteria 2GJUQ@201174,4FKBI@85023,COG0768@1,COG0768@2 NA|NA|NA M Penicillin binding protein transpeptidase domain MAG.T22.42_00520 1121924.ATWH01000025_gene1349 2.2e-179 635.6 Microbacteriaceae Bacteria 2GMPZ@201174,4FM1Q@85023,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T22.42_00521 1120960.ATXG01000003_gene2030 8.9e-144 517.3 Microbacteriaceae pknB 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 2GJ1J@201174,4FMGG@85023,COG0515@1,COG0515@2,COG2815@1,COG2815@2 NA|NA|NA KLT PASTA MAG.T22.42_00522 31964.CMS0016 2.9e-87 328.2 Microbacteriaceae trpG GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 ko:K01664,ko:K13950 ko00790,map00790 R01716 RC00010,RC01418 ko00000,ko00001,ko01000 Bacteria 2GJUX@201174,4FMRP@85023,COG0512@1,COG0512@2 NA|NA|NA EH Peptidase C26 MAG.T22.42_00523 1416759.AYMR01000034_gene4062 1.2e-11 75.1 Microbacteriaceae Bacteria 2EHSF@1,2HYH4@201174,33BI6@2,4FQHT@85023 NA|NA|NA MAG.T22.42_00524 1120960.ATXG01000003_gene2033 5.5e-74 284.3 Microbacteriaceae srtA 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 2GKT6@201174,4FNGN@85023,COG3764@1,COG3764@2 NA|NA|NA M Sortase family MAG.T22.42_00525 1389489.O159_00220 8.2e-22 109.4 Microbacteriaceae crgA Bacteria 2E4NY@1,2GQPW@201174,32ZHR@2,4FQ2Z@85023 NA|NA|NA D Involved in cell division MAG.T22.42_00526 1001240.GY21_03335 1e-76 293.5 Microbacteriaceae gluP 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 2GJYG@201174,4FKRG@85023,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family MAG.T22.42_00527 1120959.ATXF01000005_gene1493 1e-74 286.2 Microbacteriaceae ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria 2IFUE@201174,4FNJY@85023,COG0652@1,COG0652@2 NA|NA|NA O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides MAG.T22.42_00528 1120959.ATXF01000005_gene1492 1.7e-39 169.1 Microbacteriaceae Bacteria 2C9GD@1,2IMZF@201174,3422E@2,4FPCA@85023 NA|NA|NA MAG.T22.42_00529 1120960.ATXG01000003_gene2039 9.5e-50 203.0 Microbacteriaceae 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2IQZT@201174,4FPCW@85023,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain MAG.T22.42_00530 1206101.AZXC01000009_gene534 1.8e-89 336.3 Actinobacteria chaA ko:K07300 ko00000,ko02000 2.A.19 iNJ661.Rv1607 Bacteria 2GJWT@201174,COG0387@1,COG0387@2 NA|NA|NA P COG0387 Ca2 H antiporter MAG.T22.42_00531 1196322.A370_01650 3.3e-09 67.4 Clostridiaceae Bacteria 1VJRI@1239,24UCF@186801,2ED1S@1,336YP@2,36T2P@31979 NA|NA|NA MAG.T22.42_00534 1120960.ATXG01000003_gene2040 1e-23 116.3 Microbacteriaceae GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 2GKZP@201174,4FP6M@85023,COG3266@1,COG3266@2 NA|NA|NA S Transmembrane domain of unknown function (DUF3566) MAG.T22.42_00535 1121924.ATWH01000007_gene2146 0.0 1334.7 Microbacteriaceae gyrA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02469 ko00000,ko01000,ko03032,ko03400 Bacteria 2GJ2Q@201174,4FKBU@85023,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner MAG.T22.42_00536 1120959.ATXF01000005_gene1486 0.0 1079.3 Microbacteriaceae gyrB GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 2GKGP@201174,4FMXF@85023,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner MAG.T22.42_00537 1150399.AQYK01000001_gene115 2.5e-40 171.8 Microbacteriaceae Bacteria 2GNQ4@201174,4FNPN@85023,COG5512@1,COG5512@2 NA|NA|NA S Protein of unknown function (DUF721) MAG.T22.42_00538 1120960.ATXG01000003_gene2044 1.3e-114 419.9 Microbacteriaceae recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K03629,ko:K07459 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2GJCS@201174,4FKQ1@85023,COG1195@1,COG1195@2 NA|NA|NA L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP MAG.T22.42_00539 1120960.ATXG01000003_gene2045 8.9e-142 510.0 Microbacteriaceae dnaN GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJK3@201174,4FKX0@85023,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria MAG.T22.42_00540 1120959.ATXF01000005_gene1482 1e-214 752.7 Microbacteriaceae dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 2GJKI@201174,4FKHD@85023,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids MAG.T22.42_00541 1120958.AULD01000005_gene2047 1.3e-13 81.3 Microbacteriaceae rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02914 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQFY@201174,4FQ5P@85023,COG0230@1,COG0230@2 NA|NA|NA J structural constituent of ribosome MAG.T22.42_00542 1397278.AYMV01000013_gene1875 2.5e-08 64.3 Microbacteriaceae rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536,ko:K08998 ko00000,ko01000,ko03016 Bacteria 2HYH3@201174,4FQGT@85023,COG0594@1,COG0594@2 NA|NA|NA J Ribonuclease P MAG.T22.42_00543 312284.A20C1_09774 6.2e-27 126.7 unclassified Actinobacteria (class) yidD ko:K08998 ko00000 Bacteria 2GQZG@201174,3UWY8@52018,COG0759@1,COG0759@2 NA|NA|NA S Could be involved in insertion of integral membrane proteins into the membrane MAG.T22.42_00544 1120959.ATXF01000005_gene1478 1.9e-127 462.2 Microbacteriaceae yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 2GJBU@201174,4FKM2@85023,COG0706@1,COG0706@2 NA|NA|NA U 60Kd inner membrane protein MAG.T22.42_00545 1120960.ATXG01000003_gene2049 4.4e-48 197.6 Microbacteriaceae jag ko:K06346,ko:K09749 ko00000 Bacteria 2GPZK@201174,4FNQ1@85023,COG1847@1,COG1847@2 NA|NA|NA S Putative single-stranded nucleic acids-binding domain MAG.T22.42_00546 1121924.ATWH01000007_gene2136 6.5e-71 273.9 Microbacteriaceae rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 ko00000,ko01000,ko03009,ko03036 Bacteria 2GM9Z@201174,4FKMS@85023,COG0357@1,COG0357@2 NA|NA|NA M Specifically methylates the N7 position of a guanine in 16S rRNA MAG.T22.42_00547 1121924.ATWH01000007_gene2135 1e-101 376.7 Microbacteriaceae parA ko:K03496 ko00000,ko03036,ko04812 Bacteria 2GMU7@201174,4FKIH@85023,COG1192@1,COG1192@2 NA|NA|NA D Cellulose biosynthesis protein BcsQ MAG.T22.42_00548 1120960.ATXG01000003_gene2052 6.2e-118 430.6 Microbacteriaceae parB GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 2GNRN@201174,4FKH4@85023,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family MAG.T22.42_00549 1120959.ATXF01000005_gene1473 1.2e-100 373.2 Microbacteriaceae ddl 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2GRWM@201174,4FMC2@85023,COG1181@1,COG1181@2 NA|NA|NA M Belongs to the D-alanine--D-alanine ligase family MAG.T22.42_00550 1120959.ATXF01000005_gene1472 4.3e-186 657.5 Microbacteriaceae avtA ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 R01939 RC00006 ko00000,ko00001,ko01000 Bacteria 2GITW@201174,4FM0Y@85023,COG1167@1,COG1167@2 NA|NA|NA EK Alanine-glyoxylate amino-transferase MAG.T22.42_00551 1120960.ATXG01000003_gene2055 3.5e-41 174.1 Microbacteriaceae trxA 1.8.1.8 ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Bacteria 2IQ9T@201174,4FP6A@85023,COG3118@1,COG3118@2 NA|NA|NA O Thioredoxin MAG.T22.42_00552 714083.JH370377_gene798 4.6e-134 484.2 Microbacteriaceae trxB GO:0000166,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 ko:K00384,ko:K22345 ko00030,ko00450,map00030,map00450 R01544,R02016,R03596,R09372 RC00013,RC00544,RC02518,RC02873 ko00000,ko00001,ko01000 iPC815.YPO1374 Bacteria 2GKD2@201174,4FK8E@85023,COG0492@1,COG0492@2 NA|NA|NA O Pyridine nucleotide-disulphide oxidoreductase MAG.T22.42_00553 1121924.ATWH01000007_gene2129 4e-157 561.6 Microbacteriaceae murJ ko:K03980 ko00000,ko01011,ko02000 2.A.66.4 Bacteria 2GKN0@201174,4FKAK@85023,COG0728@1,COG0728@2 NA|NA|NA S MviN-like protein MAG.T22.42_00554 1120959.ATXF01000005_gene1468 3.3e-65 256.5 Microbacteriaceae Bacteria 2I9F2@201174,4FKAY@85023,COG1361@1,COG1361@2 NA|NA|NA M Conserved repeat domain MAG.T22.42_00555 1120959.ATXF01000005_gene1467 9.7e-200 703.0 Microbacteriaceae cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 2GMT1@201174,4FK78@85023,COG0617@1,COG0617@2 NA|NA|NA J Probable RNA and SrmB- binding site of polymerase A MAG.T22.42_00556 312284.A20C1_09699 2.8e-39 167.9 unclassified Actinobacteria (class) rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2IQHD@201174,3UWQU@52018,COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA MAG.T22.42_00557 1121924.ATWH01000007_gene2124 7.6e-69 266.5 Microbacteriaceae ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 2GMM3@201174,4FNEC@85023,COG0629@1,COG0629@2 NA|NA|NA L Single-strand binding protein family MAG.T22.42_00558 1121924.ATWH01000007_gene2123 8.3e-33 146.0 Microbacteriaceae rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963,ko:K03111,ko:K15125 ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133 M00178 br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400 Bacteria 2IQ92@201174,4FPGJ@85023,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit MAG.T22.42_00559 1120960.ATXG01000003_gene2063 1.6e-55 222.2 Microbacteriaceae rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKX7@201174,4FNR7@85023,COG0359@1,COG0359@2 NA|NA|NA J Binds to the 23S rRNA MAG.T22.42_00560 1449058.JQKT01000008_gene2703 2e-202 711.8 Microbacteriaceae dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 2GKXQ@201174,4FMHZ@85023,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication MAG.T22.42_00561 1120959.ATXF01000005_gene1441 1.7e-19 102.8 Microbacteriaceae Bacteria 2IRKA@201174,4FPWV@85023,COG3247@1,COG3247@2 NA|NA|NA S response to pH MAG.T22.42_00563 1120959.ATXF01000005_gene1439 2.7e-199 701.4 Microbacteriaceae purB GO:0003674,GO:0003824,GO:0004018,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 iAF1260.b1131,iBWG_1329.BWG_0979,iE2348C_1286.E2348C_1272,iEC042_1314.EC042_1202,iECABU_c1320.ECABU_c13450,iECDH10B_1368.ECDH10B_1203,iECP_1309.ECP_1126,iECUMN_1333.ECUMN_1375,iETEC_1333.ETEC_1255,iEcHS_1320.EcHS_A1251,iEcolC_1368.EcolC_2472,iJO1366.b1131,iJR904.b1131,iLF82_1304.LF82_1774,iNRG857_1313.NRG857_05460,iY75_1357.Y75_RS05905,ic_1306.c1510 Bacteria 2GM71@201174,4FKK9@85023,COG0015@1,COG0015@2 NA|NA|NA F Adenylosuccinate lyase C-terminal MAG.T22.42_00564 1121372.AULK01000003_gene106 6e-36 157.1 Microbacteriaceae 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 2IM0Q@201174,4FNWS@85023,COG0394@1,COG0394@2 NA|NA|NA T Low molecular weight phosphatase family MAG.T22.42_00565 1121924.ATWH01000007_gene2091 1.6e-30 140.6 Microbacteriaceae Bacteria 2IMH4@201174,4FPA1@85023,COG1075@1,COG1075@2 NA|NA|NA S acetyltransferases and hydrolases with the alpha beta hydrolase fold MAG.T22.42_00566 979556.MTES_1660 6.2e-116 424.1 Microbacteriaceae pat 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GJXS@201174,4FKQJ@85023,COG0079@1,COG0079@2 NA|NA|NA E May catalyze the transamination reaction in phenylalanine biosynthesis MAG.T22.42_00567 1120960.ATXG01000003_gene2117 2.8e-146 525.0 Microbacteriaceae pdhA 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GK3W@201174,4FKQ4@85023,COG1071@1,COG1071@2 NA|NA|NA C Dehydrogenase E1 component MAG.T22.42_00568 1120960.ATXG01000003_gene2118 1.3e-150 539.3 Microbacteriaceae pdhB GO:0003674,GO:0005488,GO:0005515,GO:0140030,GO:0140032 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS05355,iYO844.BSU14590 Bacteria 2GKFE@201174,4FKQ7@85023,COG0022@1,COG0022@2 NA|NA|NA C Transketolase, pyrimidine binding domain MAG.T22.42_00569 1120959.ATXF01000005_gene1424 1.6e-164 585.9 Microbacteriaceae pdhC 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GM0D@201174,4FK79@85023,COG0508@1,COG0508@2 NA|NA|NA C e3 binding domain MAG.T22.42_00570 1416759.AYMR01000011_gene597 2.5e-57 229.2 Microbacteriaceae psaA ko:K02077 M00244 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 2GM1K@201174,4FMZX@85023,COG0803@1,COG0803@2 NA|NA|NA P Zinc-uptake complex component A periplasmic MAG.T22.42_00571 1121952.ATXT01000016_gene678 1.8e-75 289.3 Microbacteriaceae fhuC ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 2GP3A@201174,4FMFD@85023,COG1121@1,COG1121@2 NA|NA|NA P ATPases associated with a variety of cellular activities MAG.T22.42_00572 1416759.AYMR01000011_gene595 4.7e-82 311.2 Microbacteriaceae znuB ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 2GJ7H@201174,4FMZ8@85023,COG1108@1,COG1108@2 NA|NA|NA P ABC 3 transport family MAG.T22.42_00573 281090.Lxx25010 2.7e-41 174.9 Microbacteriaceae zur GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02076,ko:K03711,ko:K09823 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria 2IKS3@201174,4FPDQ@85023,COG0735@1,COG0735@2 NA|NA|NA P Ferric uptake regulator family MAG.T22.42_00574 281090.Lxx25000 1.2e-33 148.7 Microbacteriaceae rpmB GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQAT@201174,4FPMY@85023,COG0227@1,COG0227@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL28 family MAG.T22.42_00575 1348338.ADILRU_2664 3.2e-22 110.2 Microbacteriaceae rpmG GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQFV@201174,4FPZQ@85023,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family MAG.T22.42_00576 1120959.ATXF01000005_gene1410 4.6e-43 180.3 Microbacteriaceae rpsN GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKN9@201174,4FP2A@85023,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site MAG.T22.42_00577 1120959.ATXF01000005_gene1409 4.2e-27 127.1 Microbacteriaceae hup GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 2IKQR@201174,4FPGU@85023,COG0776@1,COG0776@2 NA|NA|NA L bacterial (prokaryotic) histone like domain MAG.T22.42_00578 1120960.ATXG01000003_gene2134 1.3e-234 819.3 Microbacteriaceae ko:K02351,ko:K07245 ko00000,ko02000 9.B.62.1 Bacteria 2GKIR@201174,4FKRA@85023,COG1276@1,COG1276@2,COG3336@1,COG3336@2 NA|NA|NA P Copper resistance protein D MAG.T22.42_00579 1120960.ATXG01000003_gene2135 6.1e-79 301.2 Microbacteriaceae Bacteria 2IGMR@201174,4FNJG@85023,COG3087@1,COG3087@2 NA|NA|NA D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides MAG.T22.42_00580 1120960.ATXG01000003_gene2136 6.3e-158 563.9 Microbacteriaceae uvrD2 Bacteria 2HSCG@201174,4FMSB@85023,COG0507@1,COG0507@2 NA|NA|NA L PIF1-like helicase MAG.T22.42_00581 1451261.AS96_12325 1.7e-141 509.6 Actinobacteria Bacteria 2IM1V@201174,COG0477@1,COG2814@2 NA|NA|NA EGP Major Facilitator Superfamily MAG.T22.42_00582 1120958.AULD01000005_gene1991 8.8e-147 526.9 Microbacteriaceae ko:K08225 ko00000,ko02000 2.A.1.38 Bacteria 2GKFJ@201174,4FMAP@85023,COG0477@1,COG0477@2 NA|NA|NA EGP Transmembrane secretion effector MAG.T22.42_00584 1451261.AS96_05815 2.5e-96 358.2 Microbacteriaceae dcd GO:0003674,GO:0003824,GO:0004170,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0015949,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0033973,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 iPC815.YPO1525 Bacteria 2GKQQ@201174,4FKGB@85023,COG0717@1,COG0717@2 NA|NA|NA F dCTP deaminase activity MAG.T22.42_00585 1254432.SCE1572_50985 4.5e-07 62.0 Myxococcales Bacteria 1RF0G@1224,2X65S@28221,2Z39C@29,43ARQ@68525,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family MAG.T22.42_00586 1120959.ATXF01000005_gene1375 9.2e-112 410.6 Microbacteriaceae MA20_25070 ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 Bacteria 2GJCW@201174,4FKEZ@85023,COG2270@1,COG2270@2 NA|NA|NA S Vacuole effluxer Atg22 like MAG.T22.42_00587 1120959.ATXF01000005_gene1363 2.4e-304 1050.8 Microbacteriaceae dnaK GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679 ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 2GJTY@201174,4FMJW@85023,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein MAG.T22.42_00588 1120959.ATXF01000005_gene1362 8.1e-62 243.4 Microbacteriaceae grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 ko:K02652,ko:K03687 ko00000,ko02035,ko02044,ko03029,ko03110 3.A.15.2 Bacteria 2GP4F@201174,4FNVT@85023,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ MAG.T22.42_00589 1416759.AYMR01000011_gene296 1.3e-128 466.1 Microbacteriaceae dnaJ ko:K03686,ko:K05516 ko00000,ko03029,ko03036,ko03110 Bacteria 2GJKK@201174,4FM9B@85023,COG0484@1,COG0484@2 NA|NA|NA O DnaJ molecular chaperone homology domain MAG.T22.42_00590 1121952.ATXT01000016_gene643 2.2e-51 208.4 Microbacteriaceae hspR ko:K13640 ko00000,ko03000 Bacteria 2IQJ4@201174,4FP4F@85023,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance MAG.T22.42_00591 1120959.ATXF01000005_gene1357 6.1e-58 231.5 Microbacteriaceae rlmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052916,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172,2.1.1.174 ko:K00564,ko:K11391 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 2I8VY@201174,4FMGI@85023,COG2813@1,COG2813@2 NA|NA|NA J Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA MAG.T22.42_00592 1440774.Y900_023010 2e-191 675.6 Mycobacteriaceae Bacteria 232VQ@1762,2GJVW@201174,COG1574@1,COG1574@2 NA|NA|NA S amidohydrolase MAG.T22.42_00593 1389489.O159_17850 8.8e-26 122.9 Microbacteriaceae clpS GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 ko:K06891 ko00000 Bacteria 2IQ3Z@201174,4FPTZ@85023,COG2127@1,COG2127@2 NA|NA|NA S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation MAG.T22.42_00594 1120959.ATXF01000005_gene1355 8.8e-20 103.6 Microbacteriaceae Bacteria 2E4AX@1,2I15G@201174,32Z6K@2,4FQ9B@85023 NA|NA|NA S Domain of unknown function (DUF2017) MAG.T22.42_00595 1120960.ATXG01000021_gene3217 0.0 1158.7 Microbacteriaceae clpB GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K03694,ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Bacteria 2GJ73@201174,4FK4H@85023,COG0542@1,COG0542@2 NA|NA|NA O C-terminal, D2-small domain, of ClpB protein MAG.T22.42_00596 1416759.AYMR01000014_gene4113 1.4e-56 226.1 Microbacteriaceae tdsD Bacteria 2IHY1@201174,4FNRN@85023,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase family MAG.T22.42_00597 1435356.Y013_20355 2.9e-44 185.3 Nocardiaceae Bacteria 2GN4K@201174,4FWSC@85025,COG4832@1,COG4832@2 NA|NA|NA S GyrI-like small molecule binding domain MAG.T22.42_00598 1120959.ATXF01000005_gene1292 3.5e-90 338.2 Microbacteriaceae 1.1.1.105 ko:K07124,ko:K15734 ko00830,map00830 R02124 RC00649 ko00000,ko00001,ko01000 Bacteria 2IAR1@201174,4FK9W@85023,COG0300@1,COG0300@2 NA|NA|NA S Enoyl-(Acyl carrier protein) reductase MAG.T22.42_00599 1121924.ATWH01000017_gene3099 3e-142 511.5 Microbacteriaceae ltaE 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 Bacteria 2GJ0V@201174,4FKAF@85023,COG2008@1,COG2008@2 NA|NA|NA E Beta-eliminating lyase MAG.T22.42_00600 1121372.AULK01000007_gene424 8.6e-247 859.4 Microbacteriaceae aldB GO:0003674,GO:0003824,GO:0004029,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0010033,GO:0016020,GO:0016043,GO:0016491,GO:0016620,GO:0016903,GO:0022607,GO:0033554,GO:0033723,GO:0035821,GO:0042221,GO:0042493,GO:0043207,GO:0043933,GO:0044003,GO:0044085,GO:0044403,GO:0044419,GO:0044464,GO:0045471,GO:0046677,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0075136,GO:0097305,GO:1901700 1.2.1.3 ko:K00128,ko:K00138,ko:K18370 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00640,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00640,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R10703 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00545,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 iSF_1195.SF3626,iSFxv_1172.SFxv_3952,iS_1188.S4142 Bacteria 2GIWZ@201174,4FM0U@85023,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family MAG.T22.42_00601 979556.MTES_1531 1.9e-47 195.3 Microbacteriaceae ko:K09959 ko00000 Bacteria 2IKTA@201174,4FPWB@85023,COG3564@1,COG3564@2 NA|NA|NA S Protein of unknown function (DUF779) MAG.T22.42_00602 1120960.ATXG01000003_gene1828 2.1e-82 312.8 Microbacteriaceae Bacteria 2GN4Y@201174,4FMQI@85023,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter MAG.T22.42_00603 1120960.ATXG01000001_gene568 0.0 1452.6 Microbacteriaceae putA 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 Bacteria 2GM5R@201174,4FKE1@85023,COG0506@1,COG0506@2,COG1012@1,COG1012@2 NA|NA|NA CE Proline dehydrogenase MAG.T22.42_00604 1120960.ATXG01000001_gene573 7.3e-58 229.9 Microbacteriaceae ko:K03718,ko:K03719 ko00000,ko03000,ko03036 Bacteria 2GN6I@201174,4FNJI@85023,COG1522@1,COG1522@2 NA|NA|NA K Lrp/AsnC ligand binding domain MAG.T22.42_00605 1120959.ATXF01000006_gene1888 7.6e-130 470.7 Microbacteriaceae Bacteria 2GK06@201174,4FMJQ@85023,COG0477@1,COG0477@2 NA|NA|NA EGP Transmembrane secretion effector MAG.T22.42_00606 1416752.AYME01000009_gene3237 1.4e-193 682.6 Microbacteriaceae dtpT ko:K03305 ko00000 2.A.17 Bacteria 2GKB1@201174,4FN5M@85023,COG3104@1,COG3104@2 NA|NA|NA E POT family MAG.T22.42_00607 1122239.AULS01000002_gene806 1.2e-88 333.2 Microbacteriaceae pldB 3.1.1.5 ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Bacteria 2GPA8@201174,4FKKZ@85023,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 MAG.T22.42_00608 76636.JOEC01000005_gene1158 7.1e-123 446.8 Microbacteriaceae xbaIM 2.1.1.72 ko:K00571,ko:K07316 ko00000,ko01000,ko02048 Bacteria 2I8FH@201174,4FKE3@85023,COG2189@1,COG2189@2 NA|NA|NA L DNA methylase MAG.T22.42_00609 1123052.AUDF01000002_gene650 1.5e-194 686.0 Microbacteriaceae Bacteria 2GJ09@201174,4FM6U@85023,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter MAG.T22.42_00610 1120960.ATXG01000001_gene670 1.7e-69 269.6 Microbacteriaceae vanY 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Bacteria 2IN2C@201174,4FM2A@85023,COG1876@1,COG1876@2 NA|NA|NA M D-alanyl-D-alanine carboxypeptidase MAG.T22.42_00611 443906.CMM_0513 2.5e-231 808.1 Microbacteriaceae pgm GO:0000271,GO:0003674,GO:0003824,GO:0004614,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005996,GO:0006006,GO:0006012,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0016868,GO:0019318,GO:0019320,GO:0019388,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0055114,GO:0071704,GO:1901575,GO:1901576 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1376,iECED1_1282.ECED1_0670,iECNA114_1301.ECNA114_0627,iECOK1_1307.ECOK1_0699,iECP_1309.ECP_0709,iECS88_1305.ECS88_0725,iJN678.pgm,iLF82_1304.LF82_1632,iNRG857_1313.NRG857_03110,iUMN146_1321.UM146_14115,iYL1228.KPN_00711 Bacteria 2H1PI@201174,4FM6K@85023,COG0033@1,COG0033@2 NA|NA|NA G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II MAG.T22.42_00612 1120959.ATXF01000006_gene1842 1.1e-119 436.4 Microbacteriaceae pheA 1.3.1.12,4.2.1.51,5.4.99.5 ko:K04517,ko:K04518,ko:K14170 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715,R01728 RC00125,RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJQ5@201174,4FK8T@85023,COG0077@1,COG0077@2 NA|NA|NA E Prephenate dehydratase MAG.T22.42_00613 1150399.AQYK01000002_gene3254 2.7e-177 628.6 Microbacteriaceae Bacteria 2GIUM@201174,4FK8K@85023,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator Superfamily MAG.T22.42_00614 1120960.ATXG01000001_gene679 2.2e-73 282.7 Microbacteriaceae Bacteria 2GJ3K@201174,4FKAS@85023,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain MAG.T22.42_00615 1121924.ATWH01000001_gene4444 1.4e-173 615.9 Microbacteriaceae serS GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GIWP@201174,4FKF7@85023,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) MAG.T22.42_00616 1121372.AULK01000004_gene1280 1.8e-86 325.9 Microbacteriaceae Bacteria 2GP42@201174,4FK49@85023,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase MAG.T22.42_00618 1121924.ATWH01000001_gene4441 2e-95 356.3 Microbacteriaceae Bacteria 2GJM3@201174,4FM4Q@85023,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-related transcriptional attenuator domain MAG.T22.42_00620 1001240.GY21_12265 1.3e-97 363.6 Microbacteriaceae qseC GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0042221,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 ko:K02484,ko:K07637,ko:K07643,ko:K07645,ko:K07649,ko:K07653 ko01503,ko02020,ko02024,map01503,map02020,map02024 M00444,M00451,M00453,M00457,M00460,M00709,M00721,M00722,M00723,M00724,M00744 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 Bacteria 2I2VJ@201174,4FTR6@85023,COG0642@1,COG0642@2 NA|NA|NA T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain MAG.T22.42_00621 1077972.ARGLB_073_00070 5.1e-61 241.1 Actinobacteria Bacteria 2GKJK@201174,COG0745@1,COG0745@2 NA|NA|NA T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain MAG.T22.42_00623 1001240.GY21_16200 2.6e-49 202.6 Bacteria apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria COG1477@1,COG1477@2 NA|NA|NA H protein flavinylation MAG.T22.42_00624 1429046.RR21198_4080 7.8e-131 474.2 Nocardiaceae Bacteria 2GJCV@201174,4FU7D@85025,COG1018@1,COG1018@2,COG4097@1,COG4097@2 NA|NA|NA C Protein involved in monooxygenase activity, electron transporter activity, iron ion binding, electron transport, transport and aromatic compound catabolism MAG.T22.42_00625 529884.Rhola_00012670 3.4e-143 515.0 Microbacteriaceae mntH Bacteria 2GJSM@201174,4FNCM@85023,COG1914@1,COG1914@2 NA|NA|NA P Natural resistance-associated macrophage protein MAG.T22.42_00626 1151122.AQYD01000007_gene1001 1.2e-123 449.5 Microbacteriaceae yjjC ko:K01990,ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GKEH@201174,4FKJZ@85023,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities MAG.T22.42_00627 1151122.AQYD01000007_gene1002 4.8e-139 501.5 Microbacteriaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GMSI@201174,4FKKB@85023,COG3559@1,COG3559@2 NA|NA|NA M Exporter of polyketide MAG.T22.42_00628 1121924.ATWH01000011_gene323 5.5e-70 271.9 Microbacteriaceae ko:K14340 ko00000,ko01000,ko01003 Bacteria 2GN7C@201174,4FKGE@85023,COG5305@1,COG5305@2 NA|NA|NA S Dolichyl-phosphate-mannose-protein mannosyltransferase MAG.T22.42_00630 285535.JOEY01000003_gene10481 2.5e-147 528.9 Actinobacteria aldH 1.2.1.3,1.2.1.5 ko:K00128,ko:K00129 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00980,ko00981,ko00982,ko01100,ko01110,ko01120,ko01130,ko05204,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00903,map00980,map00981,map00982,map01100,map01110,map01120,map01130,map05204 M00135 R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02536,R02537,R02549,R02678,R02695,R02697,R02940,R02957,R03283,R03300,R03302,R03869,R04065,R04506,R04882,R04883,R04888,R04889,R04891,R04892,R04903,R04996,R05050,R05237,R05238,R05286,R06366,R07104,R08146,R08282,R08283,R08307 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500,RC01735 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWZ@201174,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family MAG.T22.42_00631 1120960.ATXG01000013_gene3507 1.5e-136 493.0 Microbacteriaceae dacB 3.4.16.4 ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 2GJPH@201174,4FKRJ@85023,COG2027@1,COG2027@2 NA|NA|NA M D-Ala-D-Ala carboxypeptidase 3 (S13) family MAG.T22.42_00632 1089453.GOSPT_062_00250 1.2e-25 122.9 Gordoniaceae Bacteria 2IQJ3@201174,4GEHS@85026,COG4828@1,COG4828@2 NA|NA|NA S Protein of unknown function (DUF1622) MAG.T22.42_00633 1120959.ATXF01000011_gene321 4.6e-192 677.6 Microbacteriaceae gapA GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12,4.1.1.32 ko:K00134,ko:K01596 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03320,ko04066,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,ko05010,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map03320,map04066,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R00431,R00726,R01061 RC00002,RC00149,RC02741 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iIT341.HP0921,iIT341.HP1346 Bacteria 2GJK4@201174,4FMQY@85023,COG0057@1,COG0057@2 NA|NA|NA G Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain MAG.T22.42_00634 743718.Isova_2472 2.1e-53 215.7 Promicromonosporaceae ko:K07118 ko00000 Bacteria 2GK2P@201174,4F5QG@85017,COG2910@1,COG2910@2 NA|NA|NA S NmrA-like family MAG.T22.42_00635 1121019.AUMN01000011_gene3322 4.4e-27 128.6 Actinobacteria Bacteria 2ICA7@201174,COG2084@1,COG2084@2 NA|NA|NA I 6-phosphogluconate dehydrogenase MAG.T22.42_00637 408672.NBCG_04435 1.2e-58 233.0 Propionibacteriales sdaA 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 2GJPA@201174,4DPVP@85009,COG1760@1,COG1760@2 NA|NA|NA E Serine dehydratase beta chain MAG.T22.42_00638 1122619.KB892346_gene1405 2.7e-129 468.4 Alcaligenaceae ligC 1.1.1.312 ko:K10219 ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220 M00533 R04278,R04279,R04418,R04419 RC00251,RC00254 ko00000,ko00001,ko00002,ko01000 Bacteria 1MXUP@1224,2VIRJ@28216,3T8TY@506,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.42_00639 1121022.ABENE_11275 1.5e-112 412.5 Alphaproteobacteria ligB 1.13.11.57,1.13.11.8 ko:K04099,ko:K04101 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 Bacteria 1MW77@1224,2TRP1@28211,COG3384@1,COG3384@2 NA|NA|NA S Extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols MAG.T22.42_00640 1088721.NSU_3625 8.7e-42 176.4 Sphingomonadales 1.13.11.8 ko:K04100,ko:K15777 ko00362,ko00624,ko00627,ko00965,ko01120,map00362,map00624,map00627,map00965,map01120 R01632,R03550,R04280,R08836,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 Bacteria 1RA8A@1224,2K4SD@204457,2U5U7@28211,COG3384@1,COG3384@2 NA|NA|NA S Protocatechuate 4,5-dioxygenase MAG.T22.42_00641 1118235.CAJH01000009_gene526 5.2e-127 460.7 Xanthomonadales ligI 3.1.1.57 ko:K10221 ko00362,ko00627,ko01120,map00362,map00627,map01120 R04277 RC03110 ko00000,ko00001,ko01000 Bacteria 1N2QM@1224,1RQ8V@1236,1X6AE@135614,COG3618@1,COG3618@2 NA|NA|NA S Amidohydrolase MAG.T22.42_00642 1096930.L284_14735 3.4e-154 551.2 Sphingomonadales ligJ 4.2.1.83 ko:K10220 ko00362,ko01120,map00362,map01120 R04478 RC00498 ko00000,ko00001,ko01000 Bacteria 1MVHB@1224,2K11J@204457,2TVM0@28211,COG2159@1,COG2159@2 NA|NA|NA S 4-oxalomesaconate hydratase MAG.T22.42_00643 715226.ABI_24690 2.9e-135 488.4 Caulobacterales fldA GO:0003674,GO:0003824,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016853,GO:0016860,GO:0016863,GO:0017144,GO:0018918,GO:0018958,GO:0019336,GO:0019396,GO:0019439,GO:0019752,GO:0032787,GO:0042537,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 5.3.2.8 ko:K16514 ko00362,ko01120,map00362,map01120 R07839 RC02426 ko00000,ko00001,ko01000 Bacteria 1MXVV@1224,2KI6V@204458,2TQMC@28211,COG2828@1,COG2828@2 NA|NA|NA S PrpF protein MAG.T22.42_00644 1500257.JQNM01000007_gene1615 4.6e-78 297.7 Rhizobiaceae ligK GO:0003674,GO:0003824,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0018918,GO:0018958,GO:0019336,GO:0019396,GO:0019439,GO:0019752,GO:0032787,GO:0042537,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 4.1.3.17 ko:K10218 ko00362,ko00660,ko01120,map00362,map00660,map01120 R00008,R00350 RC00067,RC00502,RC01205 ko00000,ko00001,ko01000 Bacteria 1MW9P@1224,2TTGT@28211,4B9GM@82115,COG0684@1,COG0684@2 NA|NA|NA H Aldolase/RraA MAG.T22.42_00645 543632.JOJL01000042_gene4663 5.8e-53 214.5 Micromonosporales Bacteria 2I9CD@201174,4DDE6@85008,COG1414@1,COG1414@2 NA|NA|NA K helix_turn_helix isocitrate lyase regulation MAG.T22.42_00646 1151122.AQYD01000007_gene1104 3.6e-134 485.0 Microbacteriaceae pobA 1.14.13.2 ko:K00481 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R01298 RC00046 ko00000,ko00001,ko01000 Bacteria 2GM48@201174,4FKDG@85023,COG0654@1,COG0654@2 NA|NA|NA CH FAD binding domain MAG.T22.42_00647 979556.MTES_1702 8e-71 273.9 Actinobacteria Bacteria 2I9RP@201174,COG1414@1,COG1414@2 NA|NA|NA K transcriptional regulator MAG.T22.42_00648 1150398.JIBJ01000002_gene1347 1.2e-63 250.0 Micrococcaceae Bacteria 1W8U9@1268,2I9CD@201174,COG1414@1,COG1414@2 NA|NA|NA K helix_turn_helix isocitrate lyase regulation MAG.T22.42_00649 196164.23492398 2.5e-151 542.0 Corynebacteriaceae Bacteria 22KMT@1653,2GJ8V@201174,COG2124@1,COG2124@2 NA|NA|NA C cytochrome P450 MAG.T22.42_00650 1206730.BAGA01000057_gene2518 3.8e-108 398.3 Nocardiaceae 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2101 Bacteria 2GMN4@201174,4FX0N@85025,COG0574@1,COG0574@2 NA|NA|NA GT Pyruvate phosphate dikinase, PEP/pyruvate binding domain MAG.T22.42_00651 314262.MED193_12338 5.1e-238 830.5 Alphaproteobacteria yvkC 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 Bacteria 1MV5C@1224,2U2Y8@28211,COG3848@1,COG3848@2 NA|NA|NA T PEP-utilising enzyme, mobile domain MAG.T22.42_00652 1380347.JNII01000009_gene2163 4.2e-50 204.9 Actinobacteria Bacteria 2IMKD@201174,COG1418@1,COG1418@2 NA|NA|NA S HD domain MAG.T22.42_00653 314232.SKA53_03749 2.7e-71 275.4 Loktanella Bacteria 1MXTP@1224,2P82A@245186,2TQST@28211,COG1028@1,COG1028@2 NA|NA|NA IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) MAG.T22.42_00654 591157.SSLG_00164 6.9e-29 133.3 Actinobacteria ko:K04755 ko00000 Bacteria 2GRQF@201174,COG0633@1,COG0633@2 NA|NA|NA C Ferredoxin MAG.T22.42_00655 1380386.JIAW01000030_gene3578 6.1e-118 431.0 Mycobacteriaceae 1.18.1.3,1.7.1.15 ko:K00362,ko:K00529 ko00071,ko00360,ko00910,ko01120,ko01220,map00071,map00360,map00910,map01120,map01220 M00530,M00545 R00787,R02000,R06782,R06783 RC00098,RC00176 br01602,ko00000,ko00001,ko00002,ko01000 Bacteria 23555@1762,2GJKT@201174,COG0446@1,COG0446@2 NA|NA|NA S Reductase C-terminal MAG.T22.42_00656 1001240.GY21_15595 7.3e-54 217.2 Actinobacteria Bacteria 2IBP3@201174,COG1418@1,COG1418@2 NA|NA|NA S HD domain MAG.T22.42_00657 1122138.AQUZ01000026_gene2933 1e-148 533.5 Propionibacteriales 1.2.1.3,1.2.1.8 ko:K00128,ko:K00130 ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135,M00555 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWZ@201174,4DPV7@85009,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family MAG.T22.42_00658 479434.Sthe_2822 4e-34 152.1 Thermomicrobia 3.1.3.41 ko:K01101,ko:K02566 ko00627,ko01120,map00627,map01120 R03024 RC00151 ko00000,ko00001,ko01000 Bacteria 27YYG@189775,2GBDI@200795,COG0647@1,COG0647@2 NA|NA|NA G Haloacid dehalogenase-like hydrolase MAG.T22.42_00659 479434.Sthe_2821 7.2e-116 424.5 Thermomicrobia 4.1.1.3,6.4.1.1 ko:K01571,ko:K01958,ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00217,R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 Bacteria 27Z1F@189775,2G78Z@200795,COG5016@1,COG5016@2 NA|NA|NA C Conserved carboxylase domain MAG.T22.42_00660 627192.SLG_06510 1.6e-114 419.9 Alphaproteobacteria accC 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1MU4H@1224,2TVJE@28211,COG0439@1,COG0439@2 NA|NA|NA I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism MAG.T22.42_00661 76114.ebA5773 6.1e-21 107.5 Betaproteobacteria 2.3.1.12 ko:K00627,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1PZH4@1224,2W49Q@28216,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA MAG.T22.42_00662 1122175.ATXU01000014_gene227 4.1e-79 300.8 Microbacteriaceae ko:K07497 ko00000 Bacteria 2HGQI@201174,4FKA9@85023,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase family MAG.T22.42_00663 1171373.PACID_18840 6.9e-256 889.8 Propionibacteriales Bacteria 29XB1@1,2IGPF@201174,30J0P@2,4DUB1@85009 NA|NA|NA S TIR domain MAG.T22.42_00664 1171373.PACID_18830 1.5e-224 785.4 Actinobacteria thiF 2.7.7.80 ko:K21029 ko04122,map04122 R07459 RC00043 ko00000,ko00001,ko01000 Bacteria 2ICJP@201174,COG0476@1,COG0476@2,COG5078@1,COG5078@2 NA|NA|NA H ThiF family MAG.T22.42_00665 1171373.PACID_18820 1.2e-167 595.9 Actinobacteria Bacteria 2GU0P@201174,COG1746@1,COG1746@2 NA|NA|NA J tRNA cytidylyltransferase activity MAG.T22.42_00667 450380.JPSY01000004_gene2935 2.1e-53 214.9 Actinobacteria Bacteria 2I56W@201174,COG1396@1,COG1396@2 NA|NA|NA K sequence-specific DNA binding MAG.T22.42_00668 882083.SacmaDRAFT_0386 2.7e-33 148.7 Pseudonocardiales Bacteria 2IK1U@201174,4E3HE@85010,COG2856@1,COG2856@2 NA|NA|NA E Zn peptidase MAG.T22.42_00669 450380.JPSY01000004_gene2936 1.4e-78 298.9 Microbacteriaceae Bacteria 2ADEI@1,2HD2R@201174,3134E@2,4FTB2@85023 NA|NA|NA MAG.T22.42_00670 450380.JPSY01000004_gene2937 0.0 1760.0 Actinobacteria Bacteria 2IPPT@201174,COG0457@1,COG0457@2,COG5635@1,COG5635@2 NA|NA|NA T Tetratricopeptide repeat MAG.T22.42_00671 450380.JPSY01000004_gene2938 1.1e-162 579.7 Bacteria Bacteria 2DRR1@1,33CPW@2 NA|NA|NA S SIR2-like domain MAG.T22.42_00672 312284.A20C1_10249 2.4e-13 81.3 Actinobacteria Bacteria 2BKCM@1,2GXRT@201174,32ET6@2 NA|NA|NA MAG.T22.42_00676 1343740.M271_38210 4.2e-31 142.5 Actinobacteria Bacteria 2DBRY@1,2I81X@201174,2ZANS@2 NA|NA|NA MAG.T22.42_00677 1123013.AUIC01000003_gene604 5e-11 73.9 Microbacteriaceae Bacteria 2HSW4@201174,4FQM0@85023,COG2608@1,COG2608@2 NA|NA|NA P Heavy-metal-associated domain MAG.T22.42_00682 913865.DOT_4252 8.6e-09 65.9 Peptococcaceae Bacteria 1VMFC@1239,24WT4@186801,266WT@186807,COG2002@1,COG2002@2 NA|NA|NA K toxin-antitoxin pair type II binding MAG.T22.42_00683 1123013.AUIC01000003_gene604 3.5e-12 77.8 Microbacteriaceae Bacteria 2HSW4@201174,4FQM0@85023,COG2608@1,COG2608@2 NA|NA|NA P Heavy-metal-associated domain MAG.T22.42_00684 1122239.AULS01000004_gene1334 5.6e-37 160.2 Microbacteriaceae Bacteria 2IKPX@201174,4FPV7@85023,COG4898@1,COG4898@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2200) MAG.T22.42_00685 1121952.ATXT01000002_gene1236 2.5e-20 105.1 Microbacteriaceae mutT2 3.6.1.55 ko:K03574,ko:K13669 ko00000,ko01000,ko01003,ko03400 GT87 Bacteria 2IQEA@201174,4FQ5M@85023,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain MAG.T22.42_00686 1451261.AS96_14300 3e-61 242.3 Actinobacteria ko:K07451 ko00000,ko01000,ko02048 Bacteria 2IINJ@201174,COG1403@1,COG1403@2 NA|NA|NA V HNH endonuclease MAG.T22.42_00687 140110.NechaP93899 5.4e-36 156.8 Nectriaceae Fungi 1FYAI@110618,21IBU@147550,2S210@2759,3A4D4@33154,3PSWH@4751,3RCAV@4890,3TRQR@5125,COG1694@1 NA|NA|NA F MazG-like family MAG.T22.42_00688 1278308.KB907074_gene559 8.9e-192 676.8 Microbacteriaceae ko:K09384 ko00000 Bacteria 2HNSJ@201174,4FQXN@85023,COG0507@1,COG0507@2,COG3410@1,COG3410@2 NA|NA|NA L Uncharacterized conserved protein (DUF2075) MAG.T22.42_00689 1151122.AQYD01000005_gene2901 8.7e-61 240.4 Microbacteriaceae Bacteria 2I8Y0@201174,4FQ5T@85023,COG3714@1,COG3714@2 NA|NA|NA S YhhN family MAG.T22.42_00691 1120960.ATXG01000001_gene694 1e-39 169.9 Microbacteriaceae Bacteria 2GMK7@201174,4FNSB@85023,COG5637@1,COG5637@2 NA|NA|NA S Polyketide cyclase / dehydrase and lipid transport MAG.T22.42_00692 1194165.CAJF01000022_gene3103 1.4e-37 162.2 Microbacteriaceae Bacteria 2AYGP@1,2GPGI@201174,31QJZ@2,4FPN0@85023 NA|NA|NA MAG.T22.42_00693 1449058.JQKT01000014_gene2367 2.3e-37 161.4 Microbacteriaceae Bacteria 29XEV@1,2GSA5@201174,30J54@2,4FPYT@85023 NA|NA|NA MAG.T22.42_00694 1194165.CAJF01000006_gene2466 2e-78 299.7 Microbacteriaceae ko:K06048 ko00000,ko01000 Bacteria 2GKAA@201174,4FN18@85023,COG2170@1,COG2170@2 NA|NA|NA S ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity MAG.T22.42_00695 1451261.AS96_11330 1.8e-24 118.6 Microbacteriaceae Bacteria 2DNW5@1,2IQ5T@201174,32ZGI@2,4FQ68@85023 NA|NA|NA S Rho termination factor, N-terminal domain MAG.T22.42_00696 450380.JPSY01000001_gene858 4e-44 184.5 Microbacteriaceae Bacteria 2E11E@1,2GR87@201174,32WHA@2,4FNPC@85023 NA|NA|NA MAG.T22.42_00697 1122237.AUGQ01000014_gene2687 8e-112 410.2 Microbacteriaceae Bacteria 2GJU1@201174,4FKWY@85023,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T22.42_00698 1397278.AYMV01000021_gene1849 3e-74 285.4 Microbacteriaceae Bacteria 2ICSQ@201174,4FTCD@85023,COG0583@1,COG0583@2 NA|NA|NA K Bacterial regulatory helix-turn-helix protein, lysR family MAG.T22.42_00699 714083.JH370377_gene2517 1e-154 553.5 Microbacteriaceae cad 4.1.1.18,4.1.1.19 ko:K01582,ko:K01583,ko:K01585 ko00310,ko00330,ko00960,ko01100,ko01110,map00310,map00330,map00960,map01100,map01110 M00133 R00462,R00566 RC00299 ko00000,ko00001,ko00002,ko01000 iJN678.cad Bacteria 2GJ31@201174,4FQXC@85023,COG1982@1,COG1982@2 NA|NA|NA E Orn/Lys/Arg decarboxylase, C-terminal domain MAG.T22.42_00700 483219.LILAB_14565 9.2e-95 353.6 Myxococcales mocA 1.1.1.91 ko:K05882 ko00000,ko01000 Bacteria 1MV2Y@1224,2WPP7@28221,2YTYB@29,42MVI@68525,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family MAG.T22.42_00701 1158050.KB895454_gene1355 4.8e-24 117.9 Micrococcaceae Bacteria 1WAAH@1268,2IQHK@201174,COG3152@1,COG3152@2 NA|NA|NA S Protein of unknown function (DUF805) MAG.T22.42_00702 1386089.N865_04825 4.2e-21 107.1 Intrasporangiaceae Bacteria 2EAZS@1,2I73Y@201174,32VK9@2,4FHIA@85021 NA|NA|NA S Transglycosylase associated protein MAG.T22.42_00703 1120959.ATXF01000004_gene2835 3.2e-87 328.9 Microbacteriaceae nagA 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM43@201174,4FNAD@85023,COG1472@1,COG1472@2 NA|NA|NA G Glycosyl hydrolase family 3 N terminal domain MAG.T22.42_00704 494419.ALPM01000035_gene3197 7.4e-134 484.2 Micrococcaceae lmrB ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1W7Q1@1268,2GIZX@201174,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T22.42_00705 312284.A20C1_01926 8.7e-23 113.2 unclassified Actinobacteria (class) Bacteria 2GR81@201174,3UXQS@52018,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese Homology Domain MAG.T22.42_00706 65497.JODV01000002_gene4250 1.1e-25 123.6 Pseudonocardiales Bacteria 2GMXB@201174,4E2E1@85010,COG1280@1,COG1280@2 NA|NA|NA E LysE type translocator MAG.T22.42_00707 1120960.ATXG01000008_gene280 8.2e-26 122.9 Microbacteriaceae ko:K06975 ko00000 Bacteria 2ITA4@201174,4FPJN@85023,COG2388@1,COG2388@2 NA|NA|NA S GCN5-related N-acetyl-transferase MAG.T22.42_00708 1150399.AQYK01000001_gene1990 3.7e-36 157.5 Microbacteriaceae mutT3 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 2II4D@201174,4FTJS@85023,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain MAG.T22.42_00709 1120959.ATXF01000008_gene461 3.1e-41 175.3 Microbacteriaceae pgsA GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 Bacteria 2GM3F@201174,4FNKM@85023,COG0558@1,COG0558@2 NA|NA|NA I CDP-alcohol phosphatidyltransferase MAG.T22.42_00710 1120960.ATXG01000008_gene275 3e-43 181.4 Microbacteriaceae garA Bacteria 2GK99@201174,4FNPY@85023,COG1716@1,COG1716@2 NA|NA|NA T Forkhead associated domain MAG.T22.42_00711 1001240.GY21_00535 2.7e-62 245.4 Microbacteriaceae merR1 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 Bacteria 2HBV6@201174,4FKKV@85023,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance MAG.T22.42_00712 1120959.ATXF01000008_gene464 5.3e-74 283.9 Microbacteriaceae merR2 Bacteria 2GM67@201174,4FK9E@85023,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance MAG.T22.42_00713 1150399.AQYK01000002_gene2424 2.2e-119 435.3 Microbacteriaceae parA ko:K03496 ko00000,ko03036,ko04812 Bacteria 2H4UC@201174,4FKXQ@85023,COG1192@1,COG1192@2 NA|NA|NA D AAA domain MAG.T22.42_00714 1120959.ATXF01000008_gene466 0.0 1839.7 Microbacteriaceae pyc 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS18410 Bacteria 2H238@201174,4FK6D@85023,COG1038@1,COG1038@2 NA|NA|NA C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second MAG.T22.42_00715 1120960.ATXG01000008_gene270 1.5e-114 419.9 Microbacteriaceae Bacteria 2GMK0@201174,4FMRH@85023,COG0455@1,COG0455@2 NA|NA|NA D AAA domain MAG.T22.42_00716 1120960.ATXG01000008_gene269 3.2e-62 244.6 Microbacteriaceae def 3.5.1.88 ko:K01462 ko00000,ko01000 Bacteria 2GJ87@201174,4FP05@85023,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions MAG.T22.42_00717 1120960.ATXG01000008_gene268 1.4e-243 849.0 Microbacteriaceae fadD1 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2GIXQ@201174,4FKK5@85023,COG1022@1,COG1022@2 NA|NA|NA I AMP-binding enzyme MAG.T22.42_00718 1120960.ATXG01000008_gene266 4.8e-101 374.0 Microbacteriaceae plsC 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GJ6V@201174,4FM5C@85023,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases MAG.T22.42_00719 1120960.ATXG01000008_gene265 1.4e-224 785.4 Microbacteriaceae aroH 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJBX@201174,4FKAM@85023,COG3200@1,COG3200@2 NA|NA|NA E Class-II DAHP synthetase family MAG.T22.42_00720 1120960.ATXG01000008_gene264 1.8e-188 666.0 Microbacteriaceae Bacteria 2GJ1J@201174,4FMZN@85023,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase MAG.T22.42_00721 1120960.ATXG01000008_gene263 2.2e-20 105.5 Microbacteriaceae iap GO:0005575,GO:0005576 3.2.1.17,3.5.1.104,3.5.1.28 ko:K01185,ko:K01448,ko:K01449,ko:K08307,ko:K13735,ko:K14196,ko:K19220,ko:K19223,ko:K21449,ko:K22278 ko01503,ko05100,ko05150,map01503,map05100,map05150 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02000,ko03036 1.B.40.2 CBM50 Bacteria 2I3X4@201174,4FMDC@85023,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif MAG.T22.42_00722 1150399.AQYK01000002_gene2408 8.1e-33 146.7 Microbacteriaceae GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010565,GO:0016310,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564 Bacteria 2E0H9@1,2IHPW@201174,32W34@2,4FPHY@85023 NA|NA|NA S transcriptional regulator MAG.T22.42_00723 1120960.ATXG01000008_gene261 4.3e-109 401.4 Microbacteriaceae idsA 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00365 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2GJEK@201174,4FMH8@85023,COG0142@1,COG0142@2 NA|NA|NA H Polyprenyl synthetase MAG.T22.42_00724 281090.Lxx15360 1.2e-19 102.8 Microbacteriaceae Bacteria 2E49S@1,2IHN1@201174,32Z5G@2,4FPR0@85023 NA|NA|NA S Protein of unknown function (DUF3040) MAG.T22.42_00725 1416759.AYMR01000010_gene3980 1.7e-59 235.3 Microbacteriaceae mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 ko:K03925 ko00000 Bacteria 2IHUB@201174,4FNQY@85023,COG2001@1,COG2001@2 NA|NA|NA K transcription regulator activity MAG.T22.42_00726 1120960.ATXG01000008_gene258 1.3e-115 422.9 Microbacteriaceae rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 2GJGK@201174,4FKB5@85023,COG0275@1,COG0275@2 NA|NA|NA M Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA MAG.T22.42_00727 1150399.AQYK01000002_gene2403 1.8e-20 106.3 Microbacteriaceae ftsL ko:K05589,ko:K12065 ko00000,ko02044,ko03036 3.A.7.11.1 Bacteria 2IT7S@201174,4FPPZ@85023,COG2919@1,COG2919@2 NA|NA|NA D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic MAG.T22.42_00728 1121924.ATWH01000002_gene3925 1.9e-186 659.1 Microbacteriaceae ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 2GKHH@201174,4FM11@85023,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein dimerisation domain MAG.T22.42_00729 1416759.AYMR01000010_gene3976 2.3e-170 605.5 Microbacteriaceae murE GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.10,6.3.2.13 ko:K01928,ko:K15792 ko00300,ko00550,map00300,map00550 R02788,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 iNJ661.Rv2158c Bacteria 2GIS2@201174,4FMD8@85023,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan MAG.T22.42_00730 1120959.ATXF01000008_gene483 2.6e-152 545.4 Microbacteriaceae murF 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2GK0Y@201174,4FKSH@85023,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein MAG.T22.42_00731 1120960.ATXG01000008_gene253 4.9e-151 540.8 Microbacteriaceae mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 2GNEH@201174,4FM5T@85023,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan MAG.T22.42_00732 1120960.ATXG01000008_gene252 4.3e-190 671.0 Microbacteriaceae murD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iNJ661.Rv2155c Bacteria 2GJZA@201174,4FKAU@85023,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) MAG.T22.42_00733 1120959.ATXF01000008_gene486 6.9e-101 374.4 Microbacteriaceae ftsW GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 2.4.1.227 ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 2.A.103.1 GT28 Bacteria 2GKXP@201174,4FKCX@85023,COG0772@1,COG0772@2 NA|NA|NA D Cell cycle protein MAG.T22.42_00734 1121924.ATWH01000002_gene3931 1.2e-122 446.4 Microbacteriaceae murG GO:0008150,GO:0040007 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 GT28 iLJ478.TM0232 Bacteria 2GJEM@201174,4FM76@85023,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) MAG.T22.42_00735 1120959.ATXF01000008_gene488 3.4e-189 667.9 Microbacteriaceae murC GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2I2E7@201174,4FK6M@85023,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family MAG.T22.42_00736 1451261.AS96_08205 1e-39 170.2 Microbacteriaceae ftsQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 6.3.2.4 ko:K01921,ko:K03589,ko:K06438 ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011,ko03036 Bacteria 2H4A4@201174,4FNQI@85023,COG1589@1,COG1589@2 NA|NA|NA M Cell division protein FtsQ MAG.T22.42_00737 1120960.ATXG01000008_gene247 4.5e-163 580.9 Microbacteriaceae ftsZ GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Bacteria 2GJWC@201174,4FM06@85023,COG0206@1,COG0206@2 NA|NA|NA D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity MAG.T22.42_00738 1120959.ATXF01000008_gene491 1.4e-79 302.8 Microbacteriaceae yggS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 ko:K06997 ko00000 Bacteria 2GMRJ@201174,4FM43@85023,COG0325@1,COG0325@2 NA|NA|NA S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis MAG.T22.42_00739 1348338.ADILRU_2097 2.1e-49 201.8 Microbacteriaceae sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529 ko:K09772 ko00000,ko03036 Bacteria 2GNVH@201174,4FNRK@85023,COG1799@1,COG1799@2 NA|NA|NA D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA MAG.T22.42_00740 1120959.ATXF01000008_gene493 5.3e-20 103.6 Microbacteriaceae yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02221 ko00000,ko02044 Bacteria 2GQI1@201174,4FPK2@85023,COG0762@1,COG0762@2 NA|NA|NA S YGGT family MAG.T22.42_00741 1121924.ATWH01000002_gene3939 1.9e-45 189.1 Microbacteriaceae wag31 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 Bacteria 2GMSC@201174,4FNCA@85023,COG3599@1,COG3599@2 NA|NA|NA D DivIVA protein MAG.T22.42_00742 1120959.ATXF01000008_gene495 6.2e-54 217.2 Microbacteriaceae lspA GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2GKRX@201174,4FP6Z@85023,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins MAG.T22.42_00743 1122175.ATXU01000002_gene1190 5.8e-129 467.2 Microbacteriaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 2GIY1@201174,4FK3U@85023,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil MAG.T22.42_00744 1121924.ATWH01000002_gene3942 0.0 1825.4 Microbacteriaceae dnaE 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJ1P@201174,4FK5Q@85023,COG0587@1,COG0587@2 NA|NA|NA L Helix-hairpin-helix motif MAG.T22.42_00745 1120959.ATXF01000008_gene498 3.6e-145 521.5 Microbacteriaceae hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKKA@201174,4FKH6@85023,COG0141@1,COG0141@2 NA|NA|NA E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine MAG.T22.42_00746 1120960.ATXG01000008_gene238 8.4e-46 189.5 Microbacteriaceae nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K07738 ko00000,ko03000 Bacteria 2IHU9@201174,4FNH7@85023,COG1327@1,COG1327@2 NA|NA|NA K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes MAG.T22.42_00747 1121924.ATWH01000002_gene3947 1.3e-116 426.4 Microbacteriaceae pyrD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.3.1.14,1.3.5.2,1.3.98.1 ko:K00226,ko:K00254,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01868,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKC6@201174,4FKCW@85023,COG0167@1,COG0167@2 NA|NA|NA F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor MAG.T22.42_00748 1150399.AQYK01000001_gene1914 5.7e-105 387.5 Microbacteriaceae Bacteria 2GKPS@201174,4FMAK@85023,COG4850@1,COG4850@2 NA|NA|NA S Uncharacterized conserved protein (DUF2183) MAG.T22.42_00749 1389489.O159_14510 3.8e-51 208.8 Microbacteriaceae Bacteria 2GM27@201174,4FMZK@85023,COG0501@1,COG0501@2 NA|NA|NA O Peptidase family M48 MAG.T22.42_00750 595593.JREV01000051_gene2136 1.1e-24 119.4 Micrococcaceae blaI Bacteria 1W9FB@1268,2IIIT@201174,COG3682@1,COG3682@2 NA|NA|NA K Penicillinase repressor MAG.T22.42_00751 1122175.ATXU01000008_gene306 2.7e-205 721.5 Microbacteriaceae cydA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iPC815.YPO1117,iSBO_1134.SBO_2253,iSFxv_1172.SFxv_0621,iS_1188.S0577,iSbBS512_1146.SbBS512_E2337 Bacteria 2GJE4@201174,4FM8D@85023,COG1271@1,COG1271@2 NA|NA|NA C Cytochrome bd terminal oxidase subunit I MAG.T22.42_00752 1397278.AYMV01000007_gene310 4e-110 404.8 Microbacteriaceae cydB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,ic_1306.c1120 Bacteria 2GMFV@201174,4FKHZ@85023,COG1294@1,COG1294@2 NA|NA|NA C Cytochrome bd terminal oxidase subunit II MAG.T22.42_00753 1001240.GY21_00285 7.7e-116 424.5 Microbacteriaceae cydD ko:K16013,ko:K16014 ko02010,map02010 ko00000,ko00001,ko02000 3.A.1.129 Bacteria 2I2DP@201174,4FKBJ@85023,COG4988@1,COG4988@2 NA|NA|NA V ABC transporter transmembrane region MAG.T22.42_00754 1416759.AYMR01000004_gene3499 4.2e-106 392.1 Microbacteriaceae cydC ko:K06148,ko:K16012,ko:K16014 ko02010,map02010 ko00000,ko00001,ko02000 3.A.1,3.A.1.129 Bacteria 2H79B@201174,4FN1H@85023,COG4987@1,COG4987@2 NA|NA|NA V ABC transporter transmembrane region MAG.T22.42_00755 1121924.ATWH01000002_gene3962 3.3e-79 302.4 Microbacteriaceae pabB 2.6.1.85,4.1.3.27 ko:K01657,ko:K01665,ko:K13950 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKJT@201174,4FK4S@85023,COG0147@1,COG0147@2 NA|NA|NA EH chorismate binding enzyme MAG.T22.42_00756 1120960.ATXG01000008_gene221 0.0 1326.2 Microbacteriaceae leuS 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2GJI1@201174,4FMM6@85023,COG0495@1,COG0495@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family MAG.T22.42_00757 1177594.MIC448_20011 1.5e-35 156.4 Microbacteriaceae comEA ko:K02237 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 2IQDC@201174,4FPAM@85023,COG1555@1,COG1555@2 NA|NA|NA L SLBB domain MAG.T22.42_00758 1120960.ATXG01000008_gene219 2.1e-124 453.4 Microbacteriaceae comEC ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 2GJGR@201174,4FMUX@85023,COG0658@1,COG0658@2,COG2333@1,COG2333@2 NA|NA|NA S Competence protein MAG.T22.42_00759 1348338.ADILRU_0849 1.7e-105 389.4 Microbacteriaceae holA 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GNMZ@201174,4FMG7@85023,COG1466@1,COG1466@2 NA|NA|NA L DNA polymerase III delta subunit MAG.T22.42_00760 1151122.AQYD01000005_gene3382 1.1e-21 109.0 Microbacteriaceae rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ73@201174,4FPN2@85023,COG0268@1,COG0268@2 NA|NA|NA J Binds directly to 16S ribosomal RNA MAG.T22.42_00761 1120959.ATXF01000008_gene528 0.0 1097.8 Microbacteriaceae lepA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 2GJAB@201174,4FKYU@85023,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner MAG.T22.42_00762 1121372.AULK01000001_gene2209 3.9e-40 171.8 Microbacteriaceae Bacteria 2IQ4G@201174,4FNGT@85023,COG4762@1,COG4762@2 NA|NA|NA S Domain of unknown function (DUF1990) MAG.T22.42_00763 1122175.ATXU01000008_gene290 7.8e-142 510.4 Microbacteriaceae hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 iNJ661.Rv2388c Bacteria 2GJXX@201174,4FM0K@85023,COG0635@1,COG0635@2 NA|NA|NA H Involved in the biosynthesis of porphyrin-containing compound MAG.T22.42_00764 1120960.ATXG01000008_gene209 4.2e-17 94.4 Microbacteriaceae ko:K09940 ko00000 Bacteria 2IQSV@201174,4FP2E@85023,COG3296@1,COG3296@2 NA|NA|NA S Domain of unknown function (DUF4870) MAG.T22.42_00765 1120960.ATXG01000008_gene207 7e-66 257.3 Microbacteriaceae hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03705 ko00000,ko03000 Bacteria 2GKF5@201174,4FKHR@85023,COG1420@1,COG1420@2 NA|NA|NA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons MAG.T22.42_00766 1416759.AYMR01000004_gene3482 3.3e-139 501.5 Microbacteriaceae dnaJ GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K03686 ko00000,ko03029,ko03110 Bacteria 2GK69@201174,4FK9F@85023,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins MAG.T22.42_00767 1121372.AULK01000001_gene2204 3.1e-64 251.9 Microbacteriaceae rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 1.13.12.16,2.1.1.193 ko:K00459,ko:K09761 ko00910,map00910 R00025 RC02541,RC02759 ko00000,ko00001,ko01000,ko03009 Bacteria 2GTKX@201174,4FNEM@85023,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit MAG.T22.42_00769 979556.MTES_3381 8.7e-38 162.9 Microbacteriaceae hinT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019478,GO:0019752,GO:0043436,GO:0043530,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046144,GO:0046395,GO:0046416,GO:0046436,GO:0055130,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.1.226,2.1.1.227 ko:K02503,ko:K06442 ko00000,ko01000,ko03009,ko04147 Bacteria 2IHPT@201174,4FP4E@85023,COG0537@1,COG0537@2 NA|NA|NA FG Scavenger mRNA decapping enzyme C-term binding MAG.T22.42_00770 1120959.ATXF01000008_gene537 1.3e-140 506.1 Microbacteriaceae phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06217 ko00000 Bacteria 2GK0W@201174,4FKMP@85023,COG1702@1,COG1702@2 NA|NA|NA T PhoH-like protein MAG.T22.42_00771 1121372.AULK01000001_gene2201 2.3e-65 255.0 Microbacteriaceae ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 2GMUF@201174,4FNE8@85023,COG0319@1,COG0319@2 NA|NA|NA S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA MAG.T22.42_00772 1121924.ATWH01000002_gene3983 2.3e-115 422.5 Microbacteriaceae corC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2GIWR@201174,4FMEW@85023,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain MAG.T22.42_00773 1120960.ATXG01000008_gene200 2e-118 432.2 Microbacteriaceae era GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043021,GO:0043024,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070181,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:1901363 ko:K03595 ko00000,ko03009,ko03029 Bacteria 2GJJE@201174,4FK7Q@85023,COG1159@1,COG1159@2 NA|NA|NA S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism MAG.T22.42_00774 1451261.AS96_01865 2.7e-273 947.6 Microbacteriaceae leuA GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GISX@201174,4FKQS@85023,COG0119@1,COG0119@2 NA|NA|NA E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) MAG.T22.42_00775 1120960.ATXG01000008_gene194 1.7e-61 242.7 Microbacteriaceae Bacteria 2GMI4@201174,4FNIN@85023,COG2860@1,COG2860@2 NA|NA|NA S UPF0126 domain MAG.T22.42_00776 1416759.AYMR01000004_gene3467 7.6e-100 370.2 Microbacteriaceae recO GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2GK81@201174,4FKTB@85023,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination MAG.T22.42_00777 1150399.AQYK01000001_gene1960 5.8e-120 437.2 Microbacteriaceae uppS GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86 ko:K00806,ko:K14215 ko00900,ko01110,map00900,map01110 R06447,R09244 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 2GIXF@201174,4FKWQ@85023,COG0020@1,COG0020@2 NA|NA|NA I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids MAG.T22.42_00778 1095772.CAHH01000011_gene719 3.1e-63 248.4 Actinobacteria dsbA Bacteria 2GNBC@201174,COG2761@1,COG2761@2 NA|NA|NA Q Dithiol-disulfide isomerase involved in polyketide biosynthesis MAG.T22.42_00779 1449058.JQKT01000015_gene2254 2.4e-66 260.0 Microbacteriaceae Bacteria 2GU7G@201174,4FKU4@85023,COG1403@1,COG1403@2 NA|NA|NA V Domain of unknown function (DUF222) MAG.T22.42_00780 1120960.ATXG01000008_gene184 2.9e-178 631.3 Microbacteriaceae dus GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 Bacteria 2GJ8I@201174,4FKVT@85023,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines MAG.T22.42_00781 1121372.AULK01000001_gene2189 7.5e-159 567.0 Microbacteriaceae dgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 ko:K01129 ko00230,map00230 R01856 RC00017 ko00000,ko00001,ko01000 Bacteria 2GJ8F@201174,4FKUQ@85023,COG0232@1,COG0232@2 NA|NA|NA F Phosphohydrolase-associated domain MAG.T22.42_00782 1151122.AQYD01000006_gene1847 6e-129 467.2 Microbacteriaceae ppx GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 2GMME@201174,4FKY7@85023,COG0248@1,COG0248@2 NA|NA|NA FP Ppx/GppA phosphatase family MAG.T22.42_00783 1121924.ATWH01000002_gene4006 1.1e-222 779.6 Microbacteriaceae dnaG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2GJFX@201174,4FMBJ@85023,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication MAG.T22.42_00784 1416759.AYMR01000007_gene1006 3.1e-92 345.1 Microbacteriaceae pdxB 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GP09@201174,4FKZS@85023,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MAG.T22.42_00785 31964.CMS0333 1.1e-74 287.0 Microbacteriaceae 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 Bacteria 2IISK@201174,4FNWF@85023,COG1228@1,COG1228@2 NA|NA|NA Q amidohydrolase MAG.T22.42_00786 926564.KI911694_gene945 3.3e-110 404.8 Promicromonosporaceae kynA GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009150,GO:0009165,GO:0009259,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034654,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 ko:K00453 ko00380,ko01100,map00380,map01100 M00038 R00678 RC00356 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNB1@201174,4F57D@85017,COG3483@1,COG3483@2 NA|NA|NA E Tryptophan 2,3-dioxygenase MAG.T22.42_00788 1120960.ATXG01000020_gene3336 2e-81 308.9 Microbacteriaceae Bacteria 2GN6R@201174,4FKUV@85023,COG1296@1,COG1296@2 NA|NA|NA E AzlC protein MAG.T22.42_00789 1151122.AQYD01000003_gene2585 1.5e-25 122.1 Microbacteriaceae Bacteria 2E45J@1,2GR89@201174,32Z1K@2,4FQ6H@85023 NA|NA|NA S Branched-chain amino acid transport protein (AzlD) MAG.T22.42_00790 1120959.ATXF01000008_gene568 6.5e-75 287.0 Microbacteriaceae def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0035601,GO:0036211,GO:0040007,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0098732,GO:1901564 3.5.1.88 ko:K01462 ko00000,ko01000 Bacteria 2GJ87@201174,4FNDT@85023,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions MAG.T22.42_00791 1120960.ATXG01000020_gene3339 4.1e-103 381.3 Microbacteriaceae Bacteria 2HEKX@201174,4FK73@85023,COG0697@1,COG0697@2 NA|NA|NA EG spore germination MAG.T22.42_00792 1120959.ATXF01000008_gene570 8.1e-151 540.0 Microbacteriaceae Bacteria 2GIZG@201174,4FKE8@85023,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase 4-like MAG.T22.42_00793 1151122.AQYD01000005_gene2923 1.5e-135 489.2 Microbacteriaceae tas Bacteria 2GJBG@201174,4FKYQ@85023,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family MAG.T22.42_00794 290399.Arth_4398 1.5e-29 136.0 Actinobacteria ko:K03088 ko00000,ko03021 Bacteria 2H00T@201174,COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation MAG.T22.42_00795 290399.Arth_4397 1.5e-18 99.4 Actinobacteria ko:K03088 ko00000,ko03021 Bacteria 2H00T@201174,COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation MAG.T22.42_00796 1120959.ATXF01000004_gene2465 6.1e-35 154.1 Microbacteriaceae Bacteria 2CQFE@1,2IR42@201174,32SM3@2,4FPJ3@85023 NA|NA|NA S Protein of unknown function (DUF3515) MAG.T22.42_00797 1121924.ATWH01000012_gene1267 5.1e-86 324.7 Microbacteriaceae thiL GO:0008150,GO:0040007 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2977c,iYO844.BSU05900 Bacteria 2GP6E@201174,4FKD1@85023,COG0611@1,COG0611@2 NA|NA|NA H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 MAG.T22.42_00798 1121372.AULK01000001_gene2381 2.2e-31 142.1 Microbacteriaceae rsmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 ko:K08316 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 2GQ3G@201174,4FNZ3@85023,COG0742@1,COG0742@2 NA|NA|NA L Conserved hypothetical protein 95 MAG.T22.42_00799 1120959.ATXF01000004_gene2470 3.6e-238 831.2 Microbacteriaceae recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKA3@201174,4FKFP@85023,COG1200@1,COG1200@2 NA|NA|NA L RecG wedge domain MAG.T22.42_00800 76636.JOEC01000002_gene2834 8e-61 240.0 Microbacteriaceae coaD 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN1S@201174,4FNFR@85023,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate MAG.T22.42_00801 1120959.ATXF01000004_gene2475 4.7e-53 214.2 Microbacteriaceae yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 2GJTS@201174,4FNUA@85023,COG1399@1,COG1399@2 NA|NA|NA S Uncharacterized ACR, COG1399 MAG.T22.42_00802 1348338.ADILRU_0641 1.8e-22 111.3 Microbacteriaceae rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2HSQ4@201174,4FPTP@85023,COG0333@1,COG0333@2 NA|NA|NA J structural constituent of ribosome MAG.T22.42_00803 979556.MTES_3244 3.1e-74 285.0 Microbacteriaceae rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 2GKER@201174,4FK97@85023,COG0571@1,COG0571@2 NA|NA|NA K Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism MAG.T22.42_00804 1150399.AQYK01000001_gene1701 8.3e-112 410.2 Microbacteriaceae fpg GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJNT@201174,4FKYH@85023,COG0266@1,COG0266@2 NA|NA|NA L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates MAG.T22.42_00805 1150399.AQYK01000001_gene1708 0.0 1119.0 Microbacteriaceae smc GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03529,ko:K19171 ko00000,ko02048,ko03036 Bacteria 2GK93@201174,4FKAW@85023,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning MAG.T22.42_00806 1150399.AQYK01000001_gene1710 6.7e-127 460.3 Microbacteriaceae ftsY GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 2GJQH@201174,4FKG2@85023,COG0552@1,COG0552@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) MAG.T22.42_00807 1001240.GY21_02985 4.3e-22 111.3 Microbacteriaceae Bacteria 28PC3@1,2IT6V@201174,2ZC4J@2,4FPRB@85023 NA|NA|NA S Protein of unknown function (DUF2004) MAG.T22.42_00808 1043493.BBLU01000002_gene1624 8.3e-65 253.4 Actinobacteria Bacteria 2I90W@201174,COG1670@1,COG1670@2 NA|NA|NA J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins MAG.T22.42_00809 1416759.AYMR01000009_gene3242 8.3e-221 773.1 Microbacteriaceae ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 2GK4R@201174,4FKWG@85023,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY MAG.T22.42_00810 1121952.ATXT01000011_gene3161 1.3e-49 203.0 Microbacteriaceae rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2IKU0@201174,4FNQ9@85023,COG0228@1,COG0228@2 NA|NA|NA J structural constituent of ribosome MAG.T22.42_00811 76636.JOEC01000002_gene2867 3.7e-24 117.1 Microbacteriaceae CP_0960 GO:0008150,GO:0040007 ko:K06960 ko00000 Bacteria 2IQ4C@201174,4FQ2T@85023,COG1837@1,COG1837@2 NA|NA|NA S Belongs to the UPF0109 family MAG.T22.42_00812 1121952.ATXT01000011_gene3159 4e-64 251.1 Microbacteriaceae rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 ko:K02860 ko00000,ko03009 Bacteria 2GK4I@201174,4FNCW@85023,COG0806@1,COG0806@2 NA|NA|NA J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes MAG.T22.42_00813 1451261.AS96_10060 2.7e-102 379.8 Microbacteriaceae 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria 2HTCQ@201174,4FSZD@85023,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.42_00814 1451261.AS96_10060 4.5e-90 339.3 Microbacteriaceae 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria 2HTCQ@201174,4FSZD@85023,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.42_00815 1313421.JHBV01000031_gene1399 6.1e-33 148.3 Sphingobacteriia Bacteria 1IYPW@117747,4NJQR@976,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 MAG.T22.42_00816 1121924.ATWH01000005_gene2833 5.1e-146 524.2 Microbacteriaceae 1.17.1.1 ko:K12452 ko00520,map00520 R03391,R03392 RC00230 ko00000,ko00001,ko01000 Bacteria 2GKD7@201174,4FRN0@85023,COG0399@1,COG0399@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme MAG.T22.42_00817 1121924.ATWH01000005_gene2832 5.6e-58 231.1 Microbacteriaceae fcl 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 R05692 RC01014 ko00000,ko00001,ko01000 Bacteria 2GP0W@201174,4FMFH@85023,COG0451@1,COG0451@2 NA|NA|NA GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction MAG.T22.42_00818 1121924.ATWH01000005_gene2831 1.6e-156 558.9 Microbacteriaceae gmd 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 R00888 RC00402 ko00000,ko00001,ko01000 Bacteria 2GNMA@201174,4FKP2@85023,COG1089@1,COG1089@2 NA|NA|NA M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose MAG.T22.42_00819 477641.MODMU_4734 3.9e-118 432.6 Frankiales Bacteria 2HYIN@201174,4EV8R@85013,COG5479@1,COG5479@2 NA|NA|NA M LGFP repeat MAG.T22.42_00820 1089439.KB902251_gene1491 2.3e-17 95.1 Thiotrichales arnF Bacteria 1NAUF@1224,1SGTQ@1236,4637M@72273,COG2076@1,COG2076@2 NA|NA|NA P Small Multidrug Resistance protein MAG.T22.42_00821 1045855.DSC_01875 3.8e-29 134.8 Xanthomonadales rfbC 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 Bacteria 1RDAB@1224,1S5T5@1236,1X9F1@135614,COG1898@1,COG1898@2 NA|NA|NA G Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose MAG.T22.42_00822 314230.DSM3645_11197 2.7e-30 139.4 Planctomycetes Bacteria 2J4CD@203682,COG0451@1,COG0451@2 NA|NA|NA M RmlD substrate binding domain MAG.T22.42_00823 744979.R2A130_2996 1.1e-29 137.5 Alphaproteobacteria ko:K20534 ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 Bacteria 1MWE5@1224,2TRRT@28211,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase, family 2 MAG.T22.42_00824 931627.MycrhDRAFT_5103 2e-106 392.1 Mycobacteriaceae rfbF 2.7.7.33 ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 R00956 RC00002 ko00000,ko00001,ko01000 Bacteria 235MN@1762,2GKHA@201174,COG1208@1,COG1208@2 NA|NA|NA JM Glucose-1-phosphate cytidylyltransferase MAG.T22.42_00825 1265310.CCBD010000031_gene1727 6.2e-111 407.5 Mycobacteriaceae rfbG 4.2.1.45 ko:K01709 ko00520,map00520 R02426 RC00402 ko00000,ko00001,ko01000 Bacteria 238A2@1762,2I2ZM@201174,COG0451@1,COG0451@2 NA|NA|NA M Polysaccharide biosynthesis protein MAG.T22.42_00826 264732.Moth_1929 1.6e-06 61.6 Thermoanaerobacterales Bacteria 1UT2K@1239,250ZW@186801,42IBB@68295,COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family MAG.T22.42_00827 342113.DM82_2339 1.7e-32 146.7 Proteobacteria Bacteria 1R6WH@1224,COG0463@1,COG0463@2,COG2227@1,COG2227@2 NA|NA|NA HM Glycosyl transferase family 2 MAG.T22.42_00828 1173025.GEI7407_0314 6.7e-15 88.2 Oscillatoriales galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1G6HK@1117,1HEJF@1150,COG0451@1,COG0451@2 NA|NA|NA GM epimerase dehydratase MAG.T22.42_00829 1451261.AS96_10030 1.5e-152 546.2 Microbacteriaceae capD GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192 4.2.1.115,4.2.1.135,4.2.1.46 ko:K01710,ko:K15894,ko:K15912,ko:K19421 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 M00793 R06513,R09697 RC00402,RC02609 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIXM@201174,4FMJP@85023,COG1086@1,COG1086@2 NA|NA|NA M CoA-binding domain MAG.T22.42_00830 1452535.JARD01000022_gene3350 2.7e-79 302.4 Microbacteriaceae wecB 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2GJWS@201174,4FRGB@85023,COG0381@1,COG0381@2 NA|NA|NA M UDP-N-acetylglucosamine 2-epimerase MAG.T22.42_00831 1304876.AZVC01000001_gene1592 6e-63 247.3 Micrococcaceae wbpD 2.3.1.201 ko:K13018 ko00520,map00520 R10100 RC00004,RC00166 ko00000,ko00001,ko01000,ko01005 Bacteria 1W9C6@1268,2H5M0@201174,COG0110@1,COG0110@2 NA|NA|NA S Hexapeptide repeat of succinyl-transferase MAG.T22.42_00832 450380.JPSY01000001_gene291 2.8e-146 525.0 Microbacteriaceae stsC Bacteria 2GKD7@201174,4FKBR@85023,COG0399@1,COG0399@2 NA|NA|NA M DegT/DnrJ/EryC1/StrS aminotransferase family MAG.T22.42_00833 1452536.JARE01000021_gene3158 1.9e-114 419.1 Microbacteriaceae MA20_07975 Bacteria 2GJCY@201174,4FN8S@85023,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold MAG.T22.42_00834 1150399.AQYK01000001_gene1156 3.7e-84 318.5 Microbacteriaceae Bacteria 2I7QM@201174,4FRKP@85023,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 MAG.T22.42_00835 1304865.JAGF01000001_gene2573 6.9e-37 161.8 Bacteria ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria COG2244@1,COG2244@2 NA|NA|NA S polysaccharide biosynthetic process MAG.T22.42_00836 312284.A20C1_06086 2.8e-61 243.0 Actinobacteria Bacteria 2E19N@1,2IF2A@201174,32WPX@2 NA|NA|NA S Predicted membrane protein (DUF2142) MAG.T22.42_00837 443906.CMM_2309 4.5e-21 107.5 Microbacteriaceae XK27_09090 ko:K09153 ko00000 Bacteria 2GQZ0@201174,4FPMZ@85023,COG2456@1,COG2456@2 NA|NA|NA S Uncharacterized conserved protein (DUF2304) MAG.T22.42_00838 1121924.ATWH01000005_gene2819 1e-75 290.0 Microbacteriaceae ycbB ko:K00786 ko00000,ko01000 Bacteria 2I2J1@201174,4FMKF@85023,COG1216@1,COG1216@2 NA|NA|NA S Glycosyl transferase family 2 MAG.T22.42_00839 526225.Gobs_4292 1.2e-39 171.8 Actinobacteria Bacteria 2I5FK@201174,COG1216@1,COG1216@2 NA|NA|NA S Glycosyl transferase family 2 MAG.T22.42_00840 1120959.ATXF01000004_gene2947 5.7e-50 204.1 Microbacteriaceae ko:K07015 ko00000 Bacteria 2IFFV@201174,4FPCV@85023,COG2246@1,COG2246@2 NA|NA|NA S GtrA-like protein MAG.T22.42_00841 164757.Mjls_2540 4.8e-76 291.2 Mycobacteriaceae ppm1 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 R01009 RC00005 ko00000,ko00001,ko01000,ko01003 GT2 Bacteria 234JK@1762,2IPT1@201174,COG0463@1,COG0463@2 NA|NA|NA M PFAM Glycosyl transferase family 2 MAG.T22.42_00842 1001240.GY21_17040 4.5e-68 265.0 Microbacteriaceae rgpB Bacteria 2I3WV@201174,4FTNK@85023,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 MAG.T22.42_00843 43354.JOIJ01000018_gene4786 2.3e-31 142.5 Pseudonocardiales Bacteria 2IADV@201174,4E7SZ@85010,COG1432@1,COG1432@2 NA|NA|NA S Conserved Protein MAG.T22.42_00844 1121372.AULK01000002_gene851 5.8e-59 234.6 Microbacteriaceae wbbL GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0045226,GO:0046379,GO:0071704,GO:0071944,GO:1901576 2.4.1.289 ko:K07011,ko:K16870 ko00000,ko01000,ko01003 iNJ661.Rv3265c Bacteria 2GIUN@201174,4FNJD@85023,COG1216@1,COG1216@2 NA|NA|NA M Glycosyltransferase like family 2 MAG.T22.42_00845 1120960.ATXG01000010_gene2620 2.3e-91 342.8 Microbacteriaceae Bacteria 2HRKZ@201174,4FM4V@85023,COG3307@1,COG3307@2 NA|NA|NA M -O-antigen MAG.T22.42_00846 1121924.ATWH01000005_gene2838 1.7e-126 459.5 Microbacteriaceae Bacteria 2HBS3@201174,4FM8P@85023,COG3307@1,COG3307@2 NA|NA|NA M O-Antigen ligase MAG.T22.42_00847 1348338.ADILRU_0010 8.1e-86 324.3 Microbacteriaceae manA GO:0000032,GO:0000271,GO:0003674,GO:0003824,GO:0004476,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006013,GO:0006056,GO:0006057,GO:0006139,GO:0006464,GO:0006486,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009242,GO:0009298,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019309,GO:0019318,GO:0019320,GO:0019438,GO:0019538,GO:0019673,GO:0031506,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0042546,GO:0043170,GO:0043412,GO:0043413,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046377,GO:0046483,GO:0055086,GO:0070085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.14.13.81,5.3.1.8,5.4.2.8 ko:K01809,ko:K01840,ko:K04035 ko00051,ko00520,ko00860,ko01100,ko01110,ko01130,map00051,map00520,map00860,map01100,map01110,map01130 M00114 R01818,R01819,R06265,R06266,R06267,R10068 RC00376,RC00408,RC00741,RC01491,RC01492,RC03042 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_696,iECOK1_1307.ECOK1_1731,iECS88_1305.ECS88_1659,iSFV_1184.SFV_1629,iSF_1195.SF1636,iSFxv_1172.SFxv_1833,iS_1188.S1767,iUMN146_1321.UM146_09090,iUTI89_1310.UTI89_C1801 Bacteria 2GJXC@201174,4FKSN@85023,COG1482@1,COG1482@2 NA|NA|NA G Phosphomannose isomerase type I MAG.T22.42_00848 1348338.ADILRU_0014 1.2e-46 192.2 Microbacteriaceae whiB2 ko:K18955 ko00000,ko03000 Bacteria 2CC1Y@1,2IQ4Q@201174,32RUK@2,4FP3M@85023 NA|NA|NA K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA MAG.T22.42_00849 1120960.ATXG01000010_gene2612 9.8e-229 800.4 Microbacteriaceae Bacteria 2GIUN@201174,4FKNK@85023,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 MAG.T22.42_00850 1120960.ATXG01000010_gene2611 4.8e-54 219.2 Microbacteriaceae dedD ko:K02520,ko:K03749,ko:K06204,ko:K16291 ko02026,map02026 ko00000,ko00001,ko01002,ko01011,ko03000,ko03009,ko03012,ko03021,ko03029 Bacteria 2HC8A@201174,4FKQC@85023,COG3147@1,COG3147@2 NA|NA|NA S Non-essential cell division protein that could be required for efficient cell constriction MAG.T22.42_00851 273677.BW34_02629 1.9e-93 349.0 Microbacteriaceae cof 5.2.1.8 ko:K01802 ko00000,ko01000 Bacteria 2HZD0@201174,4FKCA@85023,COG0561@1,COG0561@2 NA|NA|NA S Eukaryotic phosphomannomutase MAG.T22.42_00852 1001240.GY21_20790 4e-27 127.9 Microbacteriaceae Bacteria 2C5NV@1,2IME2@201174,33Z5P@2,4FPDR@85023 NA|NA|NA MAG.T22.42_00853 312284.A20C1_05951 4e-18 97.1 unclassified Actinobacteria (class) Bacteria 2C7XW@1,2IQ5R@201174,32RR4@2,3UWYJ@52018 NA|NA|NA S Protein of unknown function (DUF3499) MAG.T22.42_00854 1122239.AULS01000022_gene2463 3e-217 761.1 Microbacteriaceae ahcY GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 Bacteria 2GK2Q@201174,4FKHQ@85023,COG0499@1,COG0499@2 NA|NA|NA H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine MAG.T22.42_00855 1120960.ATXG01000010_gene2604 9.2e-76 290.4 Microbacteriaceae aqpZ ko:K02440,ko:K06188 ko00000,ko02000 1.A.8,1.A.8.1,1.A.8.2 Bacteria 2GKK3@201174,4FNGA@85023,COG0580@1,COG0580@2 NA|NA|NA G Major intrinsic protein MAG.T22.42_00856 1132441.KI519454_gene1078 7.3e-144 516.9 Micrococcaceae luxA_1 Bacteria 1W7RB@1268,2GKCU@201174,COG2141@1,COG2141@2 NA|NA|NA C Luciferase-like monooxygenase MAG.T22.42_00857 450380.JPSY01000001_gene1400 2.1e-120 438.7 Microbacteriaceae 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN1X@201174,4FKNZ@85023,COG2514@1,COG2514@2 NA|NA|NA S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MAG.T22.42_00858 1449058.JQKT01000010_gene2034 2.8e-96 358.2 Microbacteriaceae Bacteria 2GJE6@201174,4FM2M@85023,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal MAG.T22.42_00859 936548.HMPREF1136_1877 2.5e-08 64.3 Actinobacteria Bacteria 2A338@1,2HM47@201174,30RI6@2,4D6BK@85005 NA|NA|NA S Rv0623-like transcription factor MAG.T22.42_00860 1064537.AGSO01000011_gene2973 1.1e-33 149.4 Actinobacteria ko:K07341 ko00000,ko02048 Bacteria 2IR34@201174,COG3654@1,COG3654@2 NA|NA|NA S TIGRFAM death-on-curing family protein MAG.T22.42_00861 1120959.ATXF01000004_gene3010 1.3e-157 563.1 Microbacteriaceae mtrB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 2.7.13.3 ko:K02484,ko:K07653,ko:K07654 ko02020,map02020 M00460,M00461 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2GJ2D@201174,4FKD5@85023,COG5002@1,COG5002@2 NA|NA|NA T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain MAG.T22.42_00862 1120960.ATXG01000010_gene2596 2.6e-87 329.7 Microbacteriaceae lpqB Bacteria 2GJ5Y@201174,4FM2K@85023,COG5401@1,COG5401@2 NA|NA|NA S Lipoprotein LpqB beta-propeller domain MAG.T22.42_00864 1120960.ATXG01000010_gene2594 1.4e-65 256.1 Microbacteriaceae hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 ko:K05808 ko00000,ko03009 Bacteria 2GMYF@201174,4FNS1@85023,COG1544@1,COG1544@2 NA|NA|NA J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase MAG.T22.42_00865 1120960.ATXG01000010_gene2593 0.0 1420.6 Microbacteriaceae secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 2GIRT@201174,4FM04@85023,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane MAG.T22.42_00866 1121952.ATXT01000014_gene1466 2.4e-230 804.7 Microbacteriaceae gnd GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 iECS88_1305.ECS88_2128,iECW_1372.ECW_m2189,iEKO11_1354.EKO11_1765,iPC815.YPO1541,iWFL_1372.ECW_m2189 Bacteria 2GJ2J@201174,4FMBW@85023,COG0362@1,COG0362@2 NA|NA|NA G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH MAG.T22.42_00867 1120959.ATXF01000007_gene2382 1.8e-65 255.8 Microbacteriaceae ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02897 ko03010,map03010 M00178 ko00000,ko00001,ko00002,ko03011 Bacteria 2GJPJ@201174,4FNG9@85023,COG1825@1,COG1825@2 NA|NA|NA J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance MAG.T22.42_00868 1120959.ATXF01000007_gene2384 5.9e-71 273.9 Microbacteriaceae pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 2GKCV@201174,4FN65@85023,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis MAG.T22.42_00869 1120960.ATXG01000015_gene1551 0.0 1626.3 Microbacteriaceae mfd ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJ42@201174,4FM1S@85023,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site MAG.T22.42_00870 1120960.ATXG01000015_gene1555 2.6e-75 288.5 Microbacteriaceae mazG GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 ko:K02428 ko00230,map00230 R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 Bacteria 2GNKC@201174,4FNXD@85023,COG1694@1,COG3956@2 NA|NA|NA S MazG nucleotide pyrophosphohydrolase domain MAG.T22.42_00871 1120960.ATXG01000015_gene1558 3.3e-151 541.6 Microbacteriaceae hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GIYJ@201174,4FKPA@85023,COG0124@1,COG0124@2 NA|NA|NA J Histidyl-tRNA synthetase MAG.T22.42_00872 1120960.ATXG01000015_gene1560 3.3e-199 701.0 Microbacteriaceae eno 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 2GJAY@201174,4FKJV@85023,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis MAG.T22.42_00873 1122175.ATXU01000001_gene909 1.5e-156 559.3 Microbacteriaceae 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIX8@201174,4FKA3@85023,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA dehydrogenase, middle domain MAG.T22.42_00874 281090.Lxx17180 1.5e-19 103.2 Microbacteriaceae divIC ko:K05589,ko:K13052 ko00000,ko03036 Bacteria 2GQH7@201174,4FPPH@85023,COG2919@1,COG2919@2 NA|NA|NA D Septum formation initiator MAG.T22.42_00875 1120960.ATXG01000015_gene1562 1.6e-64 252.3 Microbacteriaceae ppx2 3.6.1.11,3.6.1.40 ko:K01524,ko:K09009 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 2I8CS@201174,4FNHR@85023,COG1507@1,COG1507@2 NA|NA|NA S Protein of unknown function (DUF501) MAG.T22.42_00876 1120960.ATXG01000015_gene1563 1.2e-132 479.9 Microbacteriaceae ko:K14645 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 2GIRE@201174,4FK62@85023,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family MAG.T22.42_00877 1120959.ATXF01000007_gene2399 4.2e-201 707.6 Microbacteriaceae ndh 1.6.99.3 ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 2GJFE@201174,4FMKE@85023,COG1252@1,COG1252@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase MAG.T22.42_00879 1121952.ATXT01000014_gene1505 2.2e-83 315.1 Microbacteriaceae lemA ko:K03744 ko00000 Bacteria 2GPS4@201174,4FK45@85023,COG1704@1,COG1704@2 NA|NA|NA S LemA family MAG.T22.42_00880 1120960.ATXG01000015_gene1575 2.2e-117 428.7 Microbacteriaceae htpX ko:K03799 M00743 ko00000,ko00002,ko01000,ko01002 Bacteria 2GMJF@201174,4FMKM@85023,COG0501@1,COG0501@2 NA|NA|NA O Peptidase family M48 MAG.T22.42_00881 1120960.ATXG01000015_gene1576 6.1e-118 431.0 Microbacteriaceae ycaQ ko:K09927 ko00000 Bacteria 2GJM7@201174,4FKAJ@85023,COG3214@1,COG3214@2 NA|NA|NA S Winged helix DNA-binding domain MAG.T22.42_00882 1120959.ATXF01000007_gene2413 8.4e-117 427.2 Microbacteriaceae GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K20469 ko00000,ko02000 2.A.86.1.7 Bacteria 2GK0H@201174,4FKN8@85023,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter MAG.T22.42_00883 1120960.ATXG01000015_gene1578 4.8e-147 527.7 Microbacteriaceae ilvA 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0356 Bacteria 2GJAG@201174,4FM63@85023,COG1171@1,COG1171@2 NA|NA|NA E Pyridoxal-phosphate dependent enzyme MAG.T22.42_00884 1001240.GY21_02560 9.7e-59 233.0 Microbacteriaceae greA GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K03624 ko00000,ko03021 Bacteria 2GNZV@201174,4FNC4@85023,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides MAG.T22.42_00885 1120959.ATXF01000007_gene2416 2.8e-21 108.2 Microbacteriaceae Bacteria 2DRBP@1,2GRH6@201174,33B4I@2,4FQ36@85023 NA|NA|NA S Domain of unknown function (DUF4307) MAG.T22.42_00886 1121372.AULK01000001_gene2640 3.3e-10 70.9 Microbacteriaceae Bacteria 28XBN@1,2GRN6@201174,2ZJ9I@2,4FQ3P@85023 NA|NA|NA MAG.T22.42_00887 1120960.ATXG01000015_gene1582 1e-99 369.8 Microbacteriaceae yplQ ko:K11068 ko00000,ko02042 Bacteria 2GJGQ@201174,4FK4N@85023,COG1272@1,COG1272@2 NA|NA|NA S Haemolysin-III related MAG.T22.42_00888 1120959.ATXF01000007_gene2419 7.8e-111 406.8 Microbacteriaceae uppS1 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 ko:K00806,ko:K12503 ko00900,ko01110,map00900,map01110 R06447,R08528 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 2GJCP@201174,4FKY2@85023,COG0020@1,COG0020@2 NA|NA|NA I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids MAG.T22.42_00889 1120960.ATXG01000015_gene1585 2.7e-204 718.0 Microbacteriaceae phoH ko:K07175 ko00000 Bacteria 2GK8U@201174,4FMEX@85023,COG1875@1,COG1875@2 NA|NA|NA T Large family of predicted nucleotide-binding domains MAG.T22.42_00890 1120959.ATXF01000010_gene191 3.8e-164 584.7 Microbacteriaceae fumC GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKWY@201174,4FK7W@85023,COG0114@1,COG0114@2 NA|NA|NA C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate MAG.T22.42_00892 1151126.AQYI01000007_gene1362 5.2e-70 270.8 Microbacteriaceae orn GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2GJR7@201174,4FKTW@85023,COG1949@1,COG1949@2 NA|NA|NA L 3'-to-5' exoribonuclease specific for small oligoribonucleotides MAG.T22.42_00893 1150399.AQYK01000001_gene15 9.4e-40 170.2 Microbacteriaceae Bacteria 2IQG2@201174,4FPAK@85023,COG3548@1,COG3548@2 NA|NA|NA S Protein of unknown function (DUF1211) MAG.T22.42_00895 1463854.JOHT01000003_gene6357 4.3e-40 170.6 Actinobacteria phnA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06193 ko01120,map01120 ko00000 Bacteria 2IKQQ@201174,COG2824@1,COG2824@2 NA|NA|NA P Alkylphosphonate utilization operon protein PhnA MAG.T22.42_00896 76636.JOEC01000002_gene2951 3.9e-100 371.3 Microbacteriaceae nadE GO:0000003,GO:0003674,GO:0003824,GO:0003952,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019954,GO:0030436,GO:0032502,GO:0033554,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_1910,iECW_1372.ECW_m1909,iEKO11_1354.EKO11_2035,iETEC_1333.ETEC_1772,iEcE24377_1341.EcE24377A_1961,iSFV_1184.SFV_1480,iSF_1195.SF1486,iSFxv_1172.SFxv_1676,iSSON_1240.SSON_1418,iS_1188.S1603,iWFL_1372.ECW_m1909 Bacteria 2HS0C@201174,4FK5S@85023,COG0171@1,COG0171@2 NA|NA|NA H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source MAG.T22.42_00898 1081644.IMCC13023_10670 8.7e-51 207.6 Microbacteriaceae ydeD Bacteria 2GKVT@201174,4FNI3@85023,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family MAG.T22.42_00899 1397278.AYMV01000018_gene860 1.9e-76 292.0 Microbacteriaceae msrA 1.8.4.11 ko:K07304 ko00000,ko01000 Bacteria 2GJ1S@201174,4FNGV@85023,COG0225@1,COG0225@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine MAG.T22.42_00900 1348338.ADILRU_0731 1.6e-30 139.4 Microbacteriaceae ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 2GQIQ@201174,4FPU3@85023,COG0629@1,COG0629@2 NA|NA|NA L Single-strand binding protein family MAG.T22.42_00901 1416759.AYMR01000009_gene3338 1.8e-26 125.9 Microbacteriaceae Bacteria 2ERM9@1,2GQCJ@201174,33J6S@2,4FPMN@85023 NA|NA|NA MAG.T22.42_00902 1121372.AULK01000001_gene2279 5.2e-285 986.5 Microbacteriaceae yjjK GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 Bacteria 2GKBQ@201174,4FK7B@85023,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter MAG.T22.42_00903 1077972.ARGLB_038_00190 5.4e-114 417.5 Micrococcaceae XK27_08080 3.1.1.53 ko:K05970 ko00000,ko01000 Bacteria 1WAFN@1268,2HZP5@201174,COG4632@1,COG4632@2 NA|NA|NA G Phosphodiester glycosidase MAG.T22.42_00904 1194165.CAJF01000020_gene2967 5.4e-86 324.7 Actinobacteria XK27_08075 Bacteria 2IB2H@201174,COG1216@1,COG1216@2 NA|NA|NA S GtrA-like protein MAG.T22.42_00905 312284.A20C1_04836 2.2e-98 365.5 unclassified Actinobacteria (class) tesB ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Bacteria 2GJ1B@201174,3UWQF@52018,COG1946@1,COG1946@2 NA|NA|NA I Acyl-CoA thioesterase MAG.T22.42_00906 1101188.KI912155_gene3721 1.8e-22 112.8 Micrococcaceae Bacteria 1W9W5@1268,2AH8W@1,2HZ70@201174,317IZ@2 NA|NA|NA MAG.T22.42_00907 1120959.ATXF01000004_gene2577 1.1e-49 202.6 Microbacteriaceae glbO GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 ko:K06886 ko00000 Bacteria 2IKPF@201174,4FNU8@85023,COG2346@1,COG2346@2 NA|NA|NA S Bacterial-like globin MAG.T22.42_00908 1120960.ATXG01000002_gene2921 8.5e-110 403.7 Microbacteriaceae mscS ko:K22044 ko00000,ko02000 1.A.23.3 Bacteria 2GMFK@201174,4FMRA@85023,COG0668@1,COG0668@2 NA|NA|NA M Mechanosensitive ion channel MAG.T22.42_00909 1121924.ATWH01000031_gene3640 0.0 1185.2 Microbacteriaceae pepN 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJJ4@201174,4FM0X@85023,COG0308@1,COG0308@2 NA|NA|NA E ERAP1-like C-terminal domain MAG.T22.42_00910 1278308.KB907079_gene2075 1.6e-69 268.9 Microbacteriaceae rpiB 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKJG@201174,4FNFT@85023,COG0698@1,COG0698@2 NA|NA|NA G Ribose/Galactose Isomerase MAG.T22.42_00911 1150399.AQYK01000001_gene1814 1.2e-140 506.1 Microbacteriaceae nei1 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0003906,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0090304,GO:0097159,GO:0097506,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 ko:K05522,ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKUI@201174,4FKHP@85023,COG0266@1,COG0266@2 NA|NA|NA L Formamidopyrimidine-DNA glycosylase N-terminal domain MAG.T22.42_00912 452863.Achl_3750 2e-120 439.5 Micrococcaceae Bacteria 1W9FU@1268,2GJVW@201174,COG1574@1,COG1574@2 NA|NA|NA S Amidohydrolase family MAG.T22.42_00913 1120959.ATXF01000004_gene2506 4e-67 261.9 Microbacteriaceae trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 2GJ1G@201174,4FMFF@85023,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family MAG.T22.42_00914 1120960.ATXG01000002_gene2856 4.5e-111 407.5 Microbacteriaceae map 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 2GKKB@201174,4FM6S@85023,COG0024@1,COG0024@2 NA|NA|NA J Metallopeptidase family M24 MAG.T22.42_00915 1121952.ATXT01000011_gene3146 1.4e-51 208.8 Microbacteriaceae rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHRT@201174,4FNQZ@85023,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site MAG.T22.42_00916 1389489.O159_06670 1.2e-68 266.5 Microbacteriaceae lepB GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2GIYN@201174,4FKGI@85023,COG0681@1,COG0681@2 NA|NA|NA U Signal peptidase, peptidase S26 MAG.T22.42_00917 1001240.GY21_02900 8.4e-50 203.8 Microbacteriaceae rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2GJFN@201174,4FNKP@85023,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids MAG.T22.42_00918 1121924.ATWH01000012_gene1231 3.3e-47 194.1 Microbacteriaceae GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2AFXT@1,2IKPZ@201174,3161G@2,4FP7S@85023 NA|NA|NA S Protein of unknown function (DUF2469) MAG.T22.42_00919 1120959.ATXF01000004_gene2523 3.4e-29 134.4 Microbacteriaceae yraN ko:K07460 ko00000 Bacteria 2IQ3X@201174,4FPTI@85023,COG0792@1,COG0792@2 NA|NA|NA L nucleic acid phosphodiester bond hydrolysis MAG.T22.42_00920 1120960.ATXG01000002_gene2864 4.9e-157 561.2 Microbacteriaceae comM ko:K07391 ko00000 Bacteria 2GJIQ@201174,4FKQ9@85023,COG0606@1,COG0606@2 NA|NA|NA O Magnesium chelatase, subunit ChlI C-terminal MAG.T22.42_00921 1120959.ATXF01000004_gene2521 4.2e-90 338.6 Microbacteriaceae dprA 5.99.1.2 ko:K03168,ko:K04096 ko00000,ko01000,ko03032,ko03400 Bacteria 2GKDA@201174,4FMCM@85023,COG0758@1,COG0758@2 NA|NA|NA LU DNA recombination-mediator protein A MAG.T22.42_00922 1416759.AYMR01000009_gene3262 2.5e-87 328.9 Microbacteriaceae xerC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 2GNDP@201174,4FKW4@85023,COG4974@1,COG4974@2 NA|NA|NA L Phage integrase, N-terminal SAM-like domain MAG.T22.42_00923 1121952.ATXT01000011_gene3137 9.4e-29 133.7 Microbacteriaceae Bacteria 2I5RA@201174,4FPK4@85023,COG4942@1,COG4942@2 NA|NA|NA D Peptidase family M23 MAG.T22.42_00924 76636.JOEC01000002_gene2899 4.1e-126 457.6 Microbacteriaceae rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GMYC@201174,4FMD3@85023,COG0052@1,COG0052@2 NA|NA|NA J structural constituent of ribosome MAG.T22.42_00925 1120960.ATXG01000002_gene2870 1.9e-123 448.7 Microbacteriaceae tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02357 ko00000,ko03012,ko03029 Bacteria 2GK4M@201174,4FKXS@85023,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome MAG.T22.42_00926 1121372.AULK01000001_gene2346 4.4e-105 387.5 Microbacteriaceae pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 2GKWQ@201174,4FK7P@85023,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP MAG.T22.42_00927 1120959.ATXF01000004_gene2530 2.4e-74 285.0 Microbacteriaceae frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 2GJ9J@201174,4FM3N@85023,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another MAG.T22.42_00928 1120959.ATXF01000004_gene2531 1.3e-91 343.2 Microbacteriaceae cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41,2.7.7.67 ko:K00981,ko:K07098,ko:K19664 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799,R08966 RC00002 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1397 Bacteria 2I7ZA@201174,4FKUP@85023,COG0575@1,COG0575@2 NA|NA|NA I Cytidylyltransferase family MAG.T22.42_00929 1389489.O159_10500 3.4e-49 201.4 Microbacteriaceae ko:K07484,ko:K17763,ko:K21471 ko00000,ko01000,ko01002,ko01011,ko03021 Bacteria 2GTPA@201174,4FNWE@85023,COG3599@1,COG3599@2 NA|NA|NA D DivIVA domain repeat protein MAG.T22.42_00930 1120960.ATXG01000002_gene2875 6e-53 214.2 Microbacteriaceae ko:K21688 ko00000 Bacteria 2I2GH@201174,4FNTU@85023,COG3583@1,COG3583@2 NA|NA|NA S G5 domain protein MAG.T22.42_00931 1121924.ATWH01000012_gene1217 9.7e-30 136.0 Microbacteriaceae Bacteria 2E3EP@1,2GQST@201174,32YDP@2,4FPHU@85023 NA|NA|NA S ATP- GTP-binding protein MAG.T22.42_00932 1121924.ATWH01000012_gene1216 6.3e-75 287.3 Microbacteriaceae ko:K07018 ko00000 Bacteria 2GP8G@201174,4FKEQ@85023,COG2945@1,COG2945@2 NA|NA|NA S hydrolase of the alpha beta MAG.T22.42_00933 1120960.ATXG01000002_gene2877 1.9e-110 406.0 Microbacteriaceae Bacteria 2GN4Y@201174,4FKEK@85023,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter MAG.T22.42_00934 1120960.ATXG01000002_gene2879 6e-106 391.7 Microbacteriaceae Bacteria 28PR0@1,2GNNZ@201174,2ZCCY@2,4FTM4@85023 NA|NA|NA MAG.T22.42_00935 1194165.CAJF01000002_gene2193 2.9e-96 358.6 Microbacteriaceae trxA2 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 2GJ7B@201174,4FMTS@85023,COG3118@1,COG3118@2 NA|NA|NA O Tetratricopeptide repeat MAG.T22.42_00936 76636.JOEC01000002_gene2488 4.2e-51 207.6 Microbacteriaceae ybaK GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K03976 ko00000,ko01000,ko03016 Bacteria 2IHS8@201174,4FNRP@85023,COG2606@1,COG2606@2 NA|NA|NA S Aminoacyl-tRNA editing domain MAG.T22.42_00937 76636.JOEC01000002_gene2912 4.7e-115 421.4 Microbacteriaceae iscS 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 2GKUT@201174,4FK4V@85023,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class-V MAG.T22.42_00938 1120960.ATXG01000002_gene2887 1.2e-157 562.8 Microbacteriaceae mnmA 2.8.1.13 ko:K00566 ko04122,map04122 R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 Bacteria 2GIUQ@201174,4FMHY@85023,COG0482@1,COG0482@2 NA|NA|NA J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 MAG.T22.42_00939 1150399.AQYK01000001_gene1757 4.9e-272 943.7 Microbacteriaceae ligA GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 2GJUY@201174,4FMNB@85023,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA MAG.T22.42_00940 1122175.ATXU01000001_gene813 2.3e-148 531.9 Microbacteriaceae aspB Bacteria 2GJ7R@201174,4FS0A@85023,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class I and II MAG.T22.42_00941 1120959.ATXF01000004_gene2549 2e-30 138.3 Microbacteriaceae gatC GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2IQJN@201174,4FPH0@85023,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) MAG.T22.42_00942 1123052.AUDF01000003_gene115 4.6e-200 704.1 Microbacteriaceae gatA GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2GJK5@201174,4FKG6@85023,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) MAG.T22.42_00943 1120959.ATXF01000004_gene2551 4.7e-229 800.4 Microbacteriaceae gatB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2GJJH@201174,4FMPP@85023,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) MAG.T22.42_00944 1120960.ATXG01000002_gene2896 1.4e-144 519.6 Microbacteriaceae dinB 2.7.7.7 ko:K02346 ko00000,ko01000,ko03400 Bacteria 2GKBI@201174,4FKWX@85023,COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII MAG.T22.42_00945 273677.BW34_00461 5.6e-18 97.1 Microbacteriaceae ytfJ Bacteria 2IR8Y@201174,4FPQZ@85023,COG3874@1,COG3874@2 NA|NA|NA S Sporulation protein YtfJ MAG.T22.42_00946 318424.EU78_27280 1.6e-52 212.6 Mycobacteriaceae ykoE ko:K16925 M00582 ko00000,ko00002,ko02000 3.A.1.30 Bacteria 234UD@1762,2IDAN@201174,COG4721@1,COG4721@2 NA|NA|NA S ABC-type cobalt transport system, permease component MAG.T22.42_00947 1416759.AYMR01000009_gene3316 4.5e-104 385.2 Microbacteriaceae ykoD ko:K01990,ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00254,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2GJ0M@201174,4FMCR@85023,COG1122@1,COG1122@2 NA|NA|NA P ATPases associated with a variety of cellular activities MAG.T22.42_00948 76636.JOEC01000002_gene2936 1.1e-34 153.7 Microbacteriaceae cbiQ ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2IDC9@201174,4FNN7@85023,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein MAG.T22.42_00949 1121924.ATWH01000012_gene1185 3.4e-27 128.3 Microbacteriaceae pabB 2.6.1.85,4.1.3.27 ko:K01657,ko:K13950 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GTAB@201174,4FP4M@85023,COG0572@1,COG0572@2 NA|NA|NA F uridine kinase MAG.T22.42_00951 312284.A20C1_00836 1.4e-135 489.2 unclassified Actinobacteria (class) atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 2GJRJ@201174,3UWCR@52018,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit MAG.T22.42_00952 1121924.ATWH01000003_gene1552 1.4e-51 209.9 Microbacteriaceae atpH GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2GMJ5@201174,4FN91@85023,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation MAG.T22.42_00953 1120960.ATXG01000007_gene380 6.6e-56 223.8 Microbacteriaceae atpF ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2GJS4@201174,4FNEE@85023,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) MAG.T22.42_00954 1120959.ATXF01000004_gene3083 5.9e-30 136.3 Microbacteriaceae atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2GQI6@201174,4FPGX@85023,COG0636@1,COG0636@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation MAG.T22.42_00955 76636.JOEC01000001_gene146 3.3e-94 351.3 Microbacteriaceae atpB ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 Bacteria 2H3PR@201174,4FM5U@85023,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane MAG.T22.42_00956 1120959.ATXF01000004_gene3081 1.1e-35 156.4 Microbacteriaceae atpI ko:K02116 ko00000,ko00194 3.A.2.1 Bacteria 2BJAR@1,2IKMF@201174,32DKN@2,4FPSN@85023 NA|NA|NA MAG.T22.42_00957 1120960.ATXG01000007_gene384 9.8e-150 536.6 Microbacteriaceae tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 ko:K02851 R08856 RC00002 ko00000,ko01000,ko01003,ko01005 Bacteria 2GIT7@201174,4FKC0@85023,COG0472@1,COG0472@2 NA|NA|NA M Glycosyl transferase family 4 MAG.T22.42_00958 1120959.ATXF01000004_gene3079 1.4e-82 312.8 Microbacteriaceae ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 2GK2X@201174,4FMDU@85023,COG0009@1,COG0009@2 NA|NA|NA J Telomere recombination MAG.T22.42_00959 1416752.AYME01000003_gene2519 8.6e-90 337.0 Microbacteriaceae prmC 2.1.1.297 ko:K02493 R10806 RC00003,RC03279 ko00000,ko01000,ko03012 Bacteria 2GMH1@201174,4FKXP@85023,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif MAG.T22.42_00960 1120959.ATXF01000004_gene3074 7.6e-129 466.8 Microbacteriaceae cysK GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIXE@201174,4FKBA@85023,COG0031@1,COG0031@2 NA|NA|NA E Pyridoxal-phosphate dependent enzyme MAG.T22.42_00961 1349820.M707_01880 7e-69 266.9 Micrococcaceae cysE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 iJN746.PP_0840 Bacteria 1W7G4@1268,2IHW5@201174,COG1045@1,COG1045@2 NA|NA|NA E Serine acetyltransferase MAG.T22.42_00962 1120960.ATXG01000007_gene392 2e-173 615.1 Microbacteriaceae prfA ko:K02835 ko00000,ko03012 Bacteria 2GJWG@201174,4FKJS@85023,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA MAG.T22.42_00963 1120959.ATXF01000004_gene3071 7.3e-122 444.5 Microbacteriaceae rho GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Bacteria 2GIWY@201174,4FM78@85023,COG1158@1,COG1158@2 NA|NA|NA K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template MAG.T22.42_00964 1120960.ATXG01000007_gene394 9.2e-119 433.3 Microbacteriaceae thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545,iSB619.SA_RS06620 Bacteria 2GKIW@201174,4FKZ1@85023,COG0083@1,COG0083@2 NA|NA|NA E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate MAG.T22.42_00965 1120960.ATXG01000007_gene396 1.7e-179 635.6 Microbacteriaceae hom GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1294,iSB619.SA_RS06610 Bacteria 2GIX9@201174,4FKBY@85023,COG0460@1,COG0460@2 NA|NA|NA E Homoserine dehydrogenase MAG.T22.42_00966 1449058.JQKT01000007_gene1929 5e-153 547.7 Microbacteriaceae lysA 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKAI@201174,4FKVV@85023,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine MAG.T22.42_00967 1151122.AQYD01000006_gene2391 2.1e-246 858.2 Microbacteriaceae argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iAF987.Gmet_1434 Bacteria 2GKQ3@201174,4FKVD@85023,COG0018@1,COG0018@2 NA|NA|NA J arginyl-tRNA aminoacylation MAG.T22.42_00968 1120960.ATXG01000007_gene400 1.4e-19 103.2 Microbacteriaceae Bacteria 2CD0D@1,2IP3F@201174,2ZCNY@2,4FPC6@85023 NA|NA|NA MAG.T22.42_00970 450380.JPSY01000001_gene187 1.4e-201 709.1 Microbacteriaceae thrC 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIRY@201174,4FKEX@85023,COG0498@1,COG0498@2 NA|NA|NA E Threonine synthase N terminus MAG.T22.42_00971 1120960.ATXG01000007_gene351 5.9e-175 620.5 Microbacteriaceae gabT 2.6.1.19,2.6.1.22 ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GIS9@201174,4FK4P@85023,COG0160@1,COG0160@2 NA|NA|NA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family MAG.T22.42_00972 1121924.ATWH01000003_gene1523 8.8e-91 340.5 Microbacteriaceae ansA 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 R00485 RC00010,RC02798 ko00000,ko00001,ko01000 Bacteria 2GJA7@201174,4FMD1@85023,COG4448@1,COG4448@2 NA|NA|NA E L-asparaginase II MAG.T22.42_00973 1121924.ATWH01000003_gene1529 4.7e-55 223.0 Microbacteriaceae ko:K03466 ko00000,ko03036 3.A.12 Bacteria 2GJBR@201174,4FKPP@85023,COG1674@1,COG1674@2 NA|NA|NA D FtsK/SpoIIIE family MAG.T22.42_00974 1120960.ATXG01000007_gene364 4.1e-64 251.5 Microbacteriaceae 3.1.3.16 ko:K01090,ko:K20074 ko00000,ko01000,ko01009 Bacteria 2GJ3M@201174,4FMWF@85023,COG0631@1,COG0631@2 NA|NA|NA T Serine/threonine phosphatases, family 2C, catalytic domain MAG.T22.42_00975 1416759.AYMR01000004_gene3549 1.2e-61 242.7 Microbacteriaceae asnC ko:K03718 ko00000,ko03000 Bacteria 2GP1P@201174,4FNCP@85023,COG1522@1,COG1522@2 NA|NA|NA K helix_turn_helix ASNC type MAG.T22.42_00976 1150399.AQYK01000001_gene1876 6.4e-225 786.6 Microbacteriaceae bioA Bacteria 2GKF6@201174,4FK8X@85023,COG0161@1,COG0161@2 NA|NA|NA H Aminotransferase class-III MAG.T22.42_00977 1121952.ATXT01000018_gene1932 1.2e-20 107.5 Microbacteriaceae Bacteria 2AR9G@1,2IFWC@201174,31GJC@2,4FNNG@85023 NA|NA|NA S Domain of unknown function (DUF4192) MAG.T22.42_00979 426716.JOAJ01000002_gene1855 2e-26 125.9 Nocardiaceae Bacteria 2GJQ1@201174,4G0U9@85025,COG1309@1,COG1309@2 NA|NA|NA K Bacterial transcriptional repressor C-terminal MAG.T22.42_00980 281090.Lxx17750 4.4e-35 154.8 Microbacteriaceae Bacteria 2C9DW@1,2IBRU@201174,2ZHWS@2,4FQHI@85023 NA|NA|NA MAG.T22.42_00982 356851.JOAN01000001_gene3776 1e-252 879.4 Micromonosporales ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4DAF0@85008,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter MAG.T22.42_00983 1121952.ATXT01000018_gene1934 1.5e-215 755.7 Microbacteriaceae ycfI GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4FKNW@85023,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region MAG.T22.42_00984 1122239.AULS01000001_gene1934 2.6e-98 365.5 Microbacteriaceae exoA Bacteria 2GMWF@201174,4FKGG@85023,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 MAG.T22.42_00985 1452535.JARD01000022_gene3323 7.8e-81 307.8 Microbacteriaceae 2.7.8.12 ko:K09809 ko00000,ko01000 Bacteria 2GM0T@201174,4FNJ2@85023,COG1887@1,COG1887@2 NA|NA|NA M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase MAG.T22.42_00986 1177594.MIC448_530040 1.8e-100 373.2 Microbacteriaceae degP ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJ96@201174,4FM10@85023,COG0265@1,COG0265@2 NA|NA|NA O PDZ domain (Also known as DHR or GLGF) MAG.T22.42_00988 1120960.ATXG01000019_gene3398 0.0 1116.7 Microbacteriaceae GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K09118 ko00000 Bacteria 2GMP3@201174,4FKE0@85023,COG1615@1,COG1615@2 NA|NA|NA S Uncharacterised protein family (UPF0182) MAG.T22.42_00989 1151122.AQYD01000005_gene3675 5.4e-97 361.3 Microbacteriaceae lon ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Bacteria 2GJDD@201174,4FK7Z@85023,COG3480@1,COG3480@2 NA|NA|NA T Lon protease (S16) C-terminal proteolytic domain MAG.T22.42_00990 1120960.ATXG01000019_gene3396 9.9e-154 550.1 Microbacteriaceae Bacteria 2GJ9K@201174,4FKJU@85023,COG5282@1,COG5282@2 NA|NA|NA S Zincin-like metallopeptidase MAG.T22.42_00991 1121372.AULK01000001_gene2566 9.6e-22 110.9 Microbacteriaceae 2.7.7.80 ko:K21029 ko04122,map04122 R07459 RC00043 ko00000,ko00001,ko01000 Bacteria 2HSM8@201174,4FP9I@85023,COG0476@1,COG0476@2 NA|NA|NA H Involved in molybdopterin and thiamine biosynthesis, family 2 MAG.T22.42_00992 1120959.ATXF01000010_gene90 8.9e-176 623.6 Microbacteriaceae uvrD2 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKRW@201174,4FM98@85023,COG0210@1,COG0210@2 NA|NA|NA L UvrD-like helicase C-terminal domain MAG.T22.42_00993 1416759.AYMR01000009_gene2937 2.2e-61 242.7 Microbacteriaceae nudC GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0033554,GO:0034641,GO:0035529,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 1.3.7.1,3.6.1.22 ko:K03426,ko:K20449 ko00760,ko01100,ko01120,ko04146,map00760,map01100,map01120,map04146 R00103,R03004,R03164,R11104 RC00002,RC02422 ko00000,ko00001,ko01000 iAF1260.b3996,iB21_1397.B21_03826,iBWG_1329.BWG_3656,iEC55989_1330.EC55989_4481,iECBD_1354.ECBD_4036,iECB_1328.ECB_03873,iECDH10B_1368.ECDH10B_4185,iECDH1ME8569_1439.ECDH1ME8569_3856,iECD_1391.ECD_03873,iECIAI1_1343.ECIAI1_4211,iECO103_1326.ECO103_4745,iECO111_1330.ECO111_4813,iECO26_1355.ECO26_5105,iECSE_1348.ECSE_4284,iECW_1372.ECW_m4355,iEKO11_1354.EKO11_4325,iETEC_1333.ETEC_4256,iEcDH1_1363.EcDH1_3998,iEcE24377_1341.EcE24377A_4539,iEcHS_1320.EcHS_A4230,iEcolC_1368.EcolC_4029,iJO1366.b3996,iPC815.YPO3736,iSSON_1240.SSON_4169,iUMNK88_1353.UMNK88_4837,iWFL_1372.ECW_m4355,iY75_1357.Y75_RS17065,iYL1228.KPN_04378 Bacteria 2GJZY@201174,4FM2C@85023,COG2816@1,COG2816@2 NA|NA|NA L NUDIX domain MAG.T22.42_00994 1120960.ATXG01000019_gene3392 1.2e-95 357.1 Microbacteriaceae mphA Bacteria 2I8R6@201174,4FKT7@85023,COG3173@1,COG3173@2 NA|NA|NA S Aminoglycoside phosphotransferase MAG.T22.42_00995 1120959.ATXF01000010_gene93 3.2e-243 848.6 Microbacteriaceae uvrD2 3.6.4.12 ko:K03657,ko:K07465 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GM2E@201174,4FMCC@85023,COG0210@1,COG0210@2,COG2887@1,COG2887@2 NA|NA|NA L PD-(D/E)XK nuclease superfamily MAG.T22.42_00996 1120959.ATXF01000010_gene94 5.7e-181 641.7 Microbacteriaceae uvrD 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJD0@201174,4FMDY@85023,COG0210@1,COG0210@2,COG2887@1,COG2887@2 NA|NA|NA L PD-(D/E)XK nuclease superfamily MAG.T22.42_00997 1120959.ATXF01000010_gene95 1.1e-14 85.5 Microbacteriaceae Bacteria 2E3M2@1,2GQQW@201174,32YJA@2,4FQ22@85023 NA|NA|NA S Protein of unknown function (DUF3107) MAG.T22.42_00998 1389489.O159_08740 1.1e-20 105.9 Microbacteriaceae Bacteria 2CGJ4@1,2GRQQ@201174,2ZRHH@2,4FQ0Q@85023 NA|NA|NA MAG.T22.42_00999 1120960.ATXG01000019_gene3387 4.7e-54 218.0 Microbacteriaceae 1.14.13.149,1.14.13.227,1.14.13.236,4.1.99.5 ko:K02611,ko:K14331,ko:K15760,ko:K18223 ko00360,ko00623,ko00640,ko01100,ko01120,ko01220,map00360,map00623,map00640,map01100,map01120,map01220 M00538 R02550,R03562,R05666,R09838,R10702 RC00269,RC00490,RC02690,RC03249 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKXZ@201174,4FNJB@85023,COG3396@1,COG3396@2 NA|NA|NA S tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like MAG.T22.42_01000 979556.MTES_3115 1e-193 682.9 Microbacteriaceae deaD 3.6.4.13 ko:K05592,ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2GIUR@201174,4FKWM@85023,COG0513@1,COG0513@2 NA|NA|NA L helicase superfamily c-terminal domain MAG.T22.42_01001 1120960.ATXG01000019_gene3385 2.4e-97 362.1 Microbacteriaceae PPA1328 3.1.3.97 ko:K07053 R00188,R11188 RC00078 ko00000,ko01000 Bacteria 2GNAP@201174,4FKP4@85023,COG0613@1,COG0613@2 NA|NA|NA S DNA polymerase alpha chain like domain MAG.T22.42_01002 1120960.ATXG01000019_gene3384 1.5e-85 323.2 Microbacteriaceae Bacteria 2I9FS@201174,4FKTH@85023,COG3021@1,COG3021@2 NA|NA|NA S Endonuclease/Exonuclease/phosphatase family MAG.T22.42_01003 1120960.ATXG01000019_gene3383 1.3e-172 612.8 Microbacteriaceae pepP 3.4.11.9 ko:K01262 ko00000,ko01000,ko01002 Bacteria 2GM7D@201174,4FM4I@85023,COG0006@1,COG0006@2 NA|NA|NA E Belongs to the peptidase M24B family MAG.T22.42_01004 749927.AMED_7760 1.1e-46 193.4 Pseudonocardiales 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 R01268 RC00100 ko00000,ko00001,ko01000 Bacteria 2I77A@201174,4E47W@85010,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family MAG.T22.42_01008 1120959.ATXF01000010_gene102 6.9e-22 110.2 Microbacteriaceae Bacteria 2E4Q9@1,2II59@201174,32ZIV@2,4FQ5J@85023 NA|NA|NA S Putative transmembrane protein (PGPGW) MAG.T22.42_01009 1120959.ATXF01000010_gene104 1.4e-144 519.6 Microbacteriaceae mgtE Bacteria 2GMMK@201174,4FKK6@85023,COG2239@1,COG2239@2 NA|NA|NA P MgtE intracellular N domain MAG.T22.42_01010 1194165.CAJF01000007_gene542 2.2e-56 225.3 Microbacteriaceae Bacteria 2GJRV@201174,4FNF8@85023,COG4420@1,COG4420@2 NA|NA|NA S Protein of unknown function (DUF1003) MAG.T22.42_01011 1451261.AS96_09025 2.6e-120 438.7 Microbacteriaceae mrp GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0040007,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03593 ko00000,ko03029,ko03036 Bacteria 2GJUZ@201174,4FKNN@85023,COG0489@1,COG0489@2 NA|NA|NA D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP MAG.T22.42_01012 1150399.AQYK01000001_gene1497 2.2e-34 151.8 Microbacteriaceae tatB ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 2IR0U@201174,4FPH9@85023,COG1826@1,COG1826@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation MAG.T22.42_01013 1120959.ATXF01000010_gene111 1.7e-55 222.6 Microbacteriaceae safC Bacteria 2GPEV@201174,4FMZJ@85023,COG4122@1,COG4122@2 NA|NA|NA S O-methyltransferase MAG.T22.42_01014 1452535.JARD01000022_gene3290 9.8e-14 81.6 Microbacteriaceae Bacteria 2E39N@1,2GQFF@201174,32Y97@2,4FQNK@85023 NA|NA|NA S Protein of unknown function (DUF3117) MAG.T22.42_01015 1120960.ATXG01000019_gene3368 1.3e-93 350.1 Microbacteriaceae Bacteria 2GJQF@201174,4FKMI@85023,COG5542@1,COG5542@2 NA|NA|NA S integral membrane protein MAG.T22.42_01016 1121924.ATWH01000011_gene275 6.9e-142 510.4 Microbacteriaceae dapE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK09@201174,4FM0C@85023,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain MAG.T22.42_01017 714083.JH370377_gene1757 4.1e-90 338.2 Microbacteriaceae dapD GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1201c Bacteria 2GIZ9@201174,4FKK1@85023,COG2171@1,COG2171@2 NA|NA|NA E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA MAG.T22.42_01018 1451261.AS96_01640 3e-200 704.5 Microbacteriaceae gltA 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ7E@201174,4FK6Y@85023,COG0372@1,COG0372@2 NA|NA|NA C Belongs to the citrate synthase family MAG.T22.42_01019 1120959.ATXF01000010_gene124 1.5e-152 545.8 Microbacteriaceae dapC Bacteria 2GJMI@201174,4FKTJ@85023,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class I and II MAG.T22.42_01020 281090.Lxx16240 1.1e-55 222.2 Microbacteriaceae fdxA ko:K05524 ko00000 Bacteria 2IKVN@201174,4FP7T@85023,COG1146@1,COG1146@2 NA|NA|NA C 4Fe-4S binding domain MAG.T22.42_01021 1120959.ATXF01000010_gene126 2.9e-18 98.2 Microbacteriaceae ko:K22136 ko00000 Bacteria 2GRSY@201174,4FQ74@85023,COG2120@1,COG2120@2 NA|NA|NA S A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics MAG.T22.42_01022 1150399.AQYK01000002_gene2517 3.8e-85 321.6 Microbacteriaceae ko:K07243 ko00000,ko02000 2.A.108.1,2.A.108.2 Bacteria 2GJ22@201174,4FKHW@85023,COG0672@1,COG0672@2 NA|NA|NA P Iron permease FTR1 family MAG.T22.42_01023 1123052.AUDF01000004_gene1921 7.9e-107 394.0 Microbacteriaceae ycdO GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0008150,GO:0015684,GO:0030001,GO:0051179,GO:0051234,GO:0070838,GO:0072511 ko:K07224 ko00000,ko02000 2.A.108.2.3 Bacteria 2GJPY@201174,4FK89@85023,COG2822@1,COG2822@2 NA|NA|NA P Imelysin MAG.T22.42_01024 1001240.GY21_01725 6.6e-155 553.9 Microbacteriaceae efeN ko:K16301 ko00000,ko01000,ko02000 2.A.108.2.3 Bacteria 2GIUB@201174,4FM6J@85023,COG2837@1,COG2837@2 NA|NA|NA P Dyp-type peroxidase family MAG.T22.42_01025 1001240.GY21_01720 1.3e-14 86.3 Microbacteriaceae Bacteria 28X2R@1,2GVRI@201174,2ZJ1A@2,4FQER@85023 NA|NA|NA MAG.T22.42_01026 68170.KL590524_gene3503 1.1e-62 246.9 Pseudonocardiales crt GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 ko:K01715,ko:K13767 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R03026,R04170,R04738,R04740,R04744,R04746 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJW5@201174,4E1EZ@85010,COG1024@1,COG1024@2 NA|NA|NA I Enoyl-CoA hydratase/isomerase MAG.T22.42_01027 1177594.MIC448_1060001 0.0 1080.1 Microbacteriaceae typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 2GJUJ@201174,4FKN5@85023,COG1217@1,COG1217@2 NA|NA|NA T Elongation factor G C-terminus MAG.T22.42_01028 408672.NBCG_01252 3.2e-93 348.6 Propionibacteriales ko:K02034 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GJ9E@201174,4DQ7K@85009,COG1173@1,COG1173@2 NA|NA|NA EP N-terminal TM domain of oligopeptide transport permease C MAG.T22.42_01029 935866.JAER01000015_gene1678 2.8e-116 426.0 Propionibacteriales ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GJXH@201174,4DNE6@85009,COG0747@1,COG0747@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle MAG.T22.42_01030 935866.JAER01000015_gene1679 7.3e-98 364.0 Propionibacteriales ko:K02033 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GK0Z@201174,4DQ5V@85009,COG0601@1,COG0601@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component MAG.T22.42_01031 1283287.KB822576_gene3518 2.8e-132 478.4 Propionibacteriales oppD ko:K02031,ko:K02032 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GIXV@201174,4DPCV@85009,COG0444@1,COG0444@2 NA|NA|NA EP Belongs to the ABC transporter superfamily MAG.T22.42_01032 1283287.KB822576_gene3517 7.5e-135 486.9 Propionibacteriales ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 2H4BW@201174,4DNHC@85009,COG4608@1,COG4608@2 NA|NA|NA E Belongs to the ABC transporter superfamily MAG.T22.42_01033 76636.JOEC01000002_gene2646 8.3e-07 60.8 Microbacteriaceae Bacteria 2BFUF@1,2HTCZ@201174,329PM@2,4FT0C@85023 NA|NA|NA MAG.T22.42_01034 281090.Lxx16410 4e-86 324.7 Microbacteriaceae ko:K07052 ko00000 Bacteria 2GK11@201174,4FMWT@85023,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity MAG.T22.42_01035 1120959.ATXF01000010_gene137 0.0 1462.2 Microbacteriaceae gcvP GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016638,GO:0016642,GO:0030312,GO:0040007,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.4.4.2 ko:K00281,ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_3318 Bacteria 2GJ11@201174,4FMZ0@85023,COG0403@1,COG0403@2,COG1003@1,COG1003@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor MAG.T22.42_01036 1001240.GY21_14120 1.4e-41 175.6 Microbacteriaceae gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 2IKN2@201174,4FP7R@85023,COG0509@1,COG0509@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein MAG.T22.42_01037 1120960.ATXG01000015_gene1630 1.1e-121 443.4 Microbacteriaceae gcvT GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 iSFV_1184.SFV_2953 Bacteria 2GJ47@201174,4FKQ2@85023,COG0404@1,COG0404@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine MAG.T22.42_01038 1123013.AUIC01000003_gene518 9e-101 373.6 Actinobacteria 3.1.2.20,3.1.2.23 ko:K01073,ko:K01075,ko:K10806 ko00130,ko00362,ko01040,ko01100,ko01110,ko01120,map00130,map00362,map01040,map01100,map01110,map01120 R01301 RC00004,RC00174 ko00000,ko00001,ko01000,ko01004 Bacteria 2GK6X@201174,COG1607@1,COG1607@2 NA|NA|NA I Acyl-CoA hydrolase MAG.T22.42_01039 1121924.ATWH01000011_gene320 4.7e-85 320.9 Microbacteriaceae nrtR 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2GNMT@201174,4FKIM@85023,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain MAG.T22.42_01040 1120960.ATXG01000015_gene1628 4.5e-191 674.1 Microbacteriaceae nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM59@201174,4FK3X@85023,COG0379@1,COG0379@2 NA|NA|NA H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate MAG.T22.42_01041 1120960.ATXG01000015_gene1627 3.7e-128 465.3 Microbacteriaceae nadB GO:0008150,GO:0040007 1.3.5.4,1.4.3.16,2.4.2.19 ko:K00244,ko:K00278,ko:K00767 ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00115,M00150,M00173 R00357,R00481,R02164,R03348 RC00006,RC00045,RC02566,RC02877 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1595 Bacteria 2I2IJ@201174,4FMCF@85023,COG0029@1,COG0029@2 NA|NA|NA H Catalyzes the oxidation of L-aspartate to iminoaspartate MAG.T22.42_01042 312284.A20C1_04061 4.3e-94 351.3 unclassified Actinobacteria (class) nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0030312,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 1.4.3.16,2.4.2.19 ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481,R03348 RC00006,RC02566,RC02877 ko00000,ko00001,ko00002,ko01000 Bacteria 2GV9P@201174,3UWIJ@52018,COG0157@1,COG0157@2 NA|NA|NA H Quinolinate phosphoribosyl transferase, N-terminal domain MAG.T22.42_01043 1120959.ATXF01000010_gene147 6.7e-106 391.0 Microbacteriaceae iscS1 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 2GKUT@201174,4FMCX@85023,COG1104@1,COG1104@2 NA|NA|NA E Beta-eliminating lyase MAG.T22.42_01045 298654.FraEuI1c_3162 4.8e-110 404.4 Actinobacteria Bacteria 2GJ4R@201174,COG0667@1,COG0667@2 NA|NA|NA C aldo keto reductase MAG.T22.42_01046 450380.JPSY01000001_gene420 5.9e-210 736.9 Microbacteriaceae fumC GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKWY@201174,4FK7W@85023,COG0114@1,COG0114@2 NA|NA|NA C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate MAG.T22.42_01047 1120960.ATXG01000015_gene1590 2.2e-66 258.8 Microbacteriaceae cah 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 Bacteria 2GT5H@201174,4FMPN@85023,COG0288@1,COG0288@2 NA|NA|NA P Reversible hydration of carbon dioxide MAG.T22.42_01048 1120959.ATXF01000010_gene189 1.2e-32 146.7 Microbacteriaceae Bacteria 2EID2@1,2IJEV@201174,33C4E@2,4FNR4@85023 NA|NA|NA S Protein of unknown function (DUF4245) MAG.T22.42_01049 1121372.AULK01000001_gene2632 7.4e-20 102.8 Microbacteriaceae xseB GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GR0U@201174,4FQ03@85023,COG1722@1,COG1722@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides MAG.T22.42_01050 1120960.ATXG01000015_gene1593 6.3e-155 553.9 Microbacteriaceae xseA GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJAS@201174,4FKW7@85023,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides MAG.T22.42_01051 1451261.AS96_01530 8.1e-148 530.0 Microbacteriaceae ispH 1.17.7.4,2.7.4.25 ko:K00945,ko:K02945,ko:K03527 ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010 M00052,M00096,M00178 R00158,R00512,R01665,R05884,R08210 RC00002,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 iIT341.HP0400,iLJ478.TM1444 Bacteria 2GIZ7@201174,4FKVM@85023,COG0761@1,COG0761@2 NA|NA|NA IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis MAG.T22.42_01052 1151122.AQYD01000007_gene33 6.2e-15 87.8 Microbacteriaceae Bacteria 29A2T@1,2GV8A@201174,2ZX46@2,4FQFQ@85023 NA|NA|NA MAG.T22.42_01053 1089453.GOSPT_129_00640 6.8e-46 190.3 Gordoniaceae MA20_05250 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria 2IIPS@201174,4GEJG@85026,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain MAG.T22.42_01054 1416759.AYMR01000020_gene54 5.4e-168 597.0 Microbacteriaceae fbaA GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 iZ_1308.Z4263 Bacteria 2GM5P@201174,4FKPH@85023,COG0191@1,COG0191@2 NA|NA|NA G Fructose-bisphosphate aldolase class-II MAG.T22.42_01055 1120959.ATXF01000010_gene181 4.7e-140 504.2 Microbacteriaceae glpX GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11,3.1.3.37 ko:K02446,ko:K11532 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R01845,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMQU@201174,4FKDT@85023,COG1494@1,COG1494@2 NA|NA|NA G Bacterial fructose-1,6-bisphosphatase, glpX-encoded MAG.T22.42_01056 1122237.AUGQ01000001_gene1143 3.1e-64 252.7 Microbacteriaceae rmuC ko:K09760 ko00000 Bacteria 2GP4U@201174,4FMID@85023,COG1322@1,COG1322@2 NA|NA|NA S RmuC family MAG.T22.42_01057 1121924.ATWH01000013_gene568 4.6e-66 257.7 Microbacteriaceae polC 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IFVF@201174,4FNCN@85023,COG0847@1,COG0847@2 NA|NA|NA L EXOIII MAG.T22.42_01058 1452535.JARD01000008_gene1816 2.1e-17 95.9 Microbacteriaceae Bacteria 2BVRF@1,2GRST@201174,33143@2,4FPTS@85023 NA|NA|NA MAG.T22.42_01059 1132441.KI519455_gene3587 4.3e-21 108.2 Micrococcaceae copC ko:K07156 ko00000,ko02000 9.B.62.2 Bacteria 1W9NQ@1268,2GMKG@201174,COG2372@1,COG2372@2 NA|NA|NA P Copper resistance protein CopC MAG.T22.42_01060 446469.Sked_11730 5.3e-29 134.4 Actinobacteria VY92_09940 ko:K09796 ko00000,ko03110 Bacteria 2IR3D@201174,COG2847@1,COG2847@2 NA|NA|NA S protein conserved in bacteria MAG.T22.42_01061 714083.JH370377_gene2040 1.7e-139 502.7 Microbacteriaceae 1.11.1.19 ko:K15733 ko00000,ko01000 Bacteria 2GIUB@201174,4FK8R@85023,COG2837@1,COG2837@2 NA|NA|NA P Dyp-type peroxidase family MAG.T22.42_01062 1120959.ATXF01000010_gene177 6.9e-166 590.1 Microbacteriaceae ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 ko:K06942 ko00000,ko03009 Bacteria 2GIXI@201174,4FKCD@85023,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner MAG.T22.42_01063 1416759.AYMR01000004_gene3589 7.5e-98 363.6 Microbacteriaceae Bacteria 2GK20@201174,4FR9C@85023,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase MAG.T22.42_01064 1121946.AUAX01000001_gene2163 8.9e-24 117.5 Micromonosporales guaA1 6.3.5.2 ko:K01951,ko:K07065 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 2GNA6@201174,4D8JU@85008,COG0518@1,COG0518@2 NA|NA|NA F glutamine amidotransferase MAG.T22.42_01065 529884.Rhola_00003850 1.7e-20 104.8 Microbacteriaceae Bacteria 2E3UG@1,2IQEJ@201174,32YRU@2,4FQRY@85023 NA|NA|NA S Domain of unknown function (DUF4287) MAG.T22.42_01066 529884.Rhola_00009770 2.4e-38 165.2 Bacteria Bacteria COG3832@1,COG3832@2 NA|NA|NA J glyoxalase III activity MAG.T22.42_01067 1298863.AUEP01000020_gene3640 2e-23 115.2 Actinobacteria 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 2IQZC@201174,COG2329@1,COG2329@2 NA|NA|NA S Antibiotic biosynthesis monooxygenase MAG.T22.42_01068 1348338.ADILRU_2569 5.3e-116 424.1 Microbacteriaceae yceA ko:K07146 ko00000 Bacteria 2GMMP@201174,4FKV8@85023,COG1054@1,COG1054@2 NA|NA|NA S Rhodanase C-terminal MAG.T22.42_01069 1172185.KB911515_gene2115 1.4e-31 142.5 Nocardiaceae Bacteria 2IKKP@201174,4G1RH@85025,COG4270@1,COG4270@2 NA|NA|NA S Membrane MAG.T22.42_01070 1380393.JHVP01000006_gene3995 7.6e-130 470.3 Frankiales Bacteria 2GNR5@201174,4ET6H@85013,COG2141@1,COG2141@2 NA|NA|NA C Flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase MAG.T22.42_01071 1238186.AOCN01000022_gene2296 1.2e-35 156.0 Microbacteriaceae metY 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 iNJ661.Rv3340 Bacteria 2I2EB@201174,4FKGM@85023,COG2873@1,COG2873@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme MAG.T22.42_01072 1120960.ATXG01000002_gene2730 6.2e-24 117.1 Microbacteriaceae Bacteria 2EBSZ@1,2ISMC@201174,335SP@2,4FPPG@85023 NA|NA|NA S Putative Flp pilus-assembly TadE/G-like MAG.T22.42_01073 1120960.ATXG01000002_gene2734 9.2e-166 589.7 Microbacteriaceae prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 2GJ0F@201174,4FK9Q@85023,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA MAG.T22.42_01074 1120960.ATXG01000002_gene2738 3e-107 395.2 Microbacteriaceae ftsE GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 ko:K09811,ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 2GJE1@201174,4FKYE@85023,COG2884@1,COG2884@2 NA|NA|NA D ATPases associated with a variety of cellular activities MAG.T22.42_01075 1120960.ATXG01000002_gene2739 4.7e-107 394.4 Microbacteriaceae ftsX GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531 ko:K09811,ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 2GJMA@201174,4FM4H@85023,COG2177@1,COG2177@2 NA|NA|NA D Part of the ABC transporter FtsEX involved in cellular division MAG.T22.42_01076 400668.Mmwyl1_0175 1.2e-52 214.2 Oceanospirillales Bacteria 1PD60@1224,1S0NJ@1236,1XMW9@135619,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator superfamily MAG.T22.42_01077 1121924.ATWH01000011_gene365 1.1e-67 262.7 Microbacteriaceae smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 2GJX1@201174,4FNEQ@85023,COG0691@1,COG0691@2 NA|NA|NA O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene MAG.T22.42_01079 935839.JAGJ01000022_gene3521 7.6e-135 487.3 Promicromonosporaceae ko:K08217 br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 Bacteria 2I2EY@201174,4F3SK@85017,COG0477@1,COG2814@2 NA|NA|NA EGP Transmembrane secretion effector MAG.T22.42_01080 1120959.ATXF01000010_gene31 1.8e-94 352.4 Microbacteriaceae hisN GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008934,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016053,GO:0016137,GO:0016138,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052745,GO:0052803,GO:0052834,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659 3.1.3.15 ko:K05602 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKZZ@201174,4FM3D@85023,COG0483@1,COG0483@2 NA|NA|NA G Inositol monophosphatase family MAG.T22.42_01082 31964.CMS0708 1.2e-59 236.1 Microbacteriaceae btuE 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 Bacteria 2IFJH@201174,4FNVB@85023,COG0386@1,COG0386@2 NA|NA|NA O Glutathione peroxidase MAG.T22.42_01084 1120960.ATXG01000002_gene2756 2.6e-35 155.6 Microbacteriaceae Bacteria 2HSP1@201174,4FPMV@85023,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family MAG.T22.42_01085 1120959.ATXF01000010_gene22 2.2e-253 882.1 Microbacteriaceae ko:K06994 ko00000 Bacteria 2GJ5A@201174,4FK7G@85023,COG2409@1,COG2409@2 NA|NA|NA D MMPL family MAG.T22.42_01086 1121924.ATWH01000012_gene1315 8.6e-49 201.8 Microbacteriaceae yhgE ko:K01421 ko00000 Bacteria 2GKEM@201174,4FM60@85023,COG1511@1,COG1511@2 NA|NA|NA S YhgE Pip domain protein MAG.T22.42_01087 443906.CMM_1083 6.1e-95 354.0 Microbacteriaceae Bacteria 2GJ6E@201174,4FMSN@85023,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T22.42_01088 1121952.ATXT01000003_gene2538 1.3e-283 981.9 Microbacteriaceae ilvD GO:0003674,GO:0003824,GO:0004160,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJIJ@201174,4FK4F@85023,COG0129@1,COG0129@2 NA|NA|NA EG dihydroxy-acid dehydratase activity MAG.T22.42_01089 1416752.AYME01000003_gene2642 1.6e-284 984.9 Microbacteriaceae ilvB 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKU4@201174,4FKM7@85023,COG0028@1,COG0028@2 NA|NA|NA E Thiamine pyrophosphate enzyme, central domain MAG.T22.42_01090 1150399.AQYK01000001_gene1611 3.9e-71 274.2 Microbacteriaceae ilvN GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ilvN,iJN678.ilvN Bacteria 2GJCH@201174,4FM2D@85023,COG0440@1,COG0440@2 NA|NA|NA E ACT domain MAG.T22.42_01091 1449058.JQKT01000007_gene1118 2.4e-168 598.2 Microbacteriaceae ilvC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKXA@201174,4FKAA@85023,COG0059@1,COG0059@2 NA|NA|NA EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate MAG.T22.42_01092 1120960.ATXG01000002_gene2776 2.6e-10 72.0 Microbacteriaceae Bacteria 2B73X@1,2IQ79@201174,3204X@2,4FPPB@85023 NA|NA|NA MAG.T22.42_01093 1121924.ATWH01000012_gene1305 5.8e-08 63.9 Microbacteriaceae Bacteria 2AYMW@1,2GZA4@201174,31QSC@2,4FQQJ@85023 NA|NA|NA MAG.T22.42_01094 1120960.ATXG01000002_gene2778 2.5e-241 841.3 Microbacteriaceae serA GO:0003674,GO:0003824,GO:0004617,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJGA@201174,4FMFN@85023,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain MAG.T22.42_01095 1120959.ATXF01000010_gene4 1.3e-153 549.3 Microbacteriaceae leuB 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GK44@201174,4FK8M@85023,COG0473@1,COG0473@2 NA|NA|NA CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate MAG.T22.42_01096 1120959.ATXF01000010_gene3 1.8e-166 592.0 Microbacteriaceae ilvE GO:0000082,GO:0000278,GO:0003674,GO:0003824,GO:0004084,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006573,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008283,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009082,GO:0009083,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0022402,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044770,GO:0044772,GO:0044843,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607,GO:1903047 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GKJ1@201174,4FK6I@85023,COG0115@1,COG0115@2 NA|NA|NA EH Amino-transferase class IV MAG.T22.42_01097 450380.JPSY01000001_gene45 1e-94 353.2 Microbacteriaceae fahA Bacteria 2GN2G@201174,4FKZX@85023,COG0179@1,COG0179@2 NA|NA|NA Q Domain of unknown function (DUF2437) MAG.T22.42_01098 1177594.MIC448_10005 1.8e-112 412.9 Microbacteriaceae Bacteria 2GIR8@201174,4FKHU@85023,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T22.42_01099 1120959.ATXF01000004_gene2426 5.8e-235 820.1 Microbacteriaceae gltX GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 iNJ661.Rv2992c Bacteria 2GJJS@201174,4FM66@85023,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) MAG.T22.42_01102 1416752.AYME01000003_gene2675 5.9e-64 250.8 Microbacteriaceae Bacteria 2GNHK@201174,4FN27@85023,COG2220@1,COG2220@2 NA|NA|NA S Beta-lactamase superfamily domain MAG.T22.42_01103 1348338.ADILRU_0611 9.9e-84 317.0 Microbacteriaceae dagK GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2GK3P@201174,4FM8T@85023,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain MAG.T22.42_01105 1120959.ATXF01000004_gene2446 1e-147 529.6 Microbacteriaceae terC ko:K05794 ko00000 Bacteria 2GIWU@201174,4FKQ5@85023,COG0861@1,COG0861@2 NA|NA|NA P Integral membrane protein TerC family MAG.T22.42_01106 1120960.ATXG01000002_gene2803 9.2e-243 845.9 Microbacteriaceae leuC GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 iEcE24377_1341.EcE24377A_0075,iPC815.YPO0531 Bacteria 2GKT7@201174,4FKI7@85023,COG0065@1,COG0065@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate MAG.T22.42_01107 1416759.AYMR01000009_gene3210 3.5e-87 327.8 Microbacteriaceae leuD 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ8Z@201174,4FM8Y@85023,COG0066@1,COG0066@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate MAG.T22.42_01108 1120959.ATXF01000004_gene2460 2.9e-217 761.1 Microbacteriaceae murA 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 2GJPW@201174,4FKIF@85023,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine MAG.T22.42_01109 1120960.ATXG01000002_gene2806 1.3e-94 352.8 Microbacteriaceae plsC1 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GKVA@201174,4FKY5@85023,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases MAG.T22.42_01110 1121924.ATWH01000012_gene1270 3.1e-145 521.5 Microbacteriaceae gpsA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 Bacteria 2GJSD@201174,4FKTC@85023,COG0240@1,COG0240@2 NA|NA|NA C NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus MAG.T22.42_01111 1416759.AYMR01000009_gene3216 3.3e-119 434.9 Microbacteriaceae ddl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008716,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464,GO:0050896 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iAF1260.b0381,iB21_1397.B21_00332,iBWG_1329.BWG_0265,iE2348C_1286.E2348C_0317,iEC042_1314.EC042_0413,iEC55989_1330.EC55989_0386,iECBD_1354.ECBD_3283,iECB_1328.ECB_00328,iECDH10B_1368.ECDH10B_0338,iECDH1ME8569_1439.ECDH1ME8569_0367,iECD_1391.ECD_00328,iECH74115_1262.ECH74115_0453,iECIAI1_1343.ECIAI1_0377,iECIAI39_1322.ECIAI39_0301,iECO103_1326.ECO103_0356,iECO111_1330.ECO111_0411,iECO26_1355.ECO26_0414,iECSE_1348.ECSE_0401,iECSP_1301.ECSP_0441,iECs_1301.ECs0431,iETEC_1333.ETEC_0434,iEcDH1_1363.EcDH1_3227,iEcE24377_1341.EcE24377A_0406,iEcHS_1320.EcHS_A0447,iEcSMS35_1347.EcSMS35_0410,iEcolC_1368.EcolC_3251,iJO1366.b0381,iJR904.b0381,iSF_1195.SF0232,iSFxv_1172.SFxv_0245,iS_1188.S0254,iUMNK88_1353.UMNK88_429,iY75_1357.Y75_RS01965,iZ_1308.Z0477 Bacteria 2GITC@201174,4FMHU@85023,COG1181@1,COG1181@2 NA|NA|NA M Belongs to the D-alanine--D-alanine ligase family MAG.T22.42_01113 1120959.ATXF01000001_gene362 8e-28 130.6 Microbacteriaceae Bacteria 2HPSR@201174,4FPQ1@85023,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family MAG.T22.42_01114 1120960.ATXG01000018_gene1379 3.4e-70 271.2 Microbacteriaceae Bacteria 299E4@1,2GM90@201174,2ZWGX@2,4FNJQ@85023 NA|NA|NA S Protein of unknown function (DUF3145) MAG.T22.42_01115 1416759.AYMR01000007_gene974 1.1e-186 659.4 Microbacteriaceae fabF 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GIY4@201174,4FKVX@85023,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP MAG.T22.42_01116 1121372.AULK01000001_gene2169 2.3e-29 134.4 Microbacteriaceae acpP ko:K02078 ko00000,ko00001 Bacteria 2IQ43@201174,4FPIS@85023,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis MAG.T22.42_01117 1120960.ATXG01000018_gene1376 1.5e-146 525.8 Microbacteriaceae fabH 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GJP8@201174,4FKXT@85023,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids MAG.T22.42_01118 450380.JPSY01000003_gene2692 1e-101 376.7 Microbacteriaceae fabD GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005835,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180,2.3.1.39 ko:K00645,ko:K00648 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082,M00083 R01626,R10707,R11671 RC00004,RC00039,RC02727,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GME0@201174,4FM50@85023,COG0331@1,COG0331@2 NA|NA|NA I Acyl transferase domain MAG.T22.42_01120 1120959.ATXF01000001_gene368 6.5e-156 557.0 Microbacteriaceae Bacteria 2GN0S@201174,4FMJT@85023,COG2508@1,COG2508@2 NA|NA|NA QT PucR C-terminal helix-turn-helix domain MAG.T22.42_01121 1120960.ATXG01000018_gene1373 0.0 1587.8 Microbacteriaceae aceE GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0004739,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016624,GO:0016903,GO:0030312,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046872,GO:0055114,GO:0071944,GO:1902494,GO:1990204 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GJRE@201174,4FKV4@85023,COG2609@1,COG2609@2 NA|NA|NA C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) MAG.T22.42_01122 1122175.ATXU01000002_gene1480 8e-47 193.4 Microbacteriaceae ahpE GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 2GKME@201174,4FP6J@85023,COG1225@1,COG1225@2 NA|NA|NA O Redoxin MAG.T22.42_01124 1416752.AYME01000009_gene3201 1e-183 649.4 Microbacteriaceae rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 ko00000,ko01000,ko03009 Bacteria 2GJ48@201174,4FKM0@85023,COG0820@1,COG0820@2 NA|NA|NA J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs MAG.T22.42_01125 1150399.AQYK01000002_gene2359 3.8e-95 354.8 Microbacteriaceae yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKHZ@201174,4FMA6@85023,COG0327@1,COG0327@2 NA|NA|NA S NIF3 (NGG1p interacting factor 3) MAG.T22.42_01126 1120959.ATXF01000001_gene372 4.4e-47 194.9 Microbacteriaceae ko:K07164 ko00000 Bacteria 2GP84@201174,4FP1K@85023,COG1579@1,COG1579@2 NA|NA|NA S Zn-ribbon protein, possibly nucleic acid-binding MAG.T22.42_01127 1177594.MIC448_320061 2.3e-45 188.3 Microbacteriaceae rnhA GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 ko:K03469,ko:K06864,ko:K22316 ko00860,ko01100,ko03030,map00860,map01100,map03030 M00122 R04594 RC00017 ko00000,ko00001,ko00002,ko01000,ko03032 Bacteria 2I4IN@201174,4FP3Z@85023,COG0328@1,COG0328@2 NA|NA|NA L Reverse transcriptase-like MAG.T22.42_01129 1123052.AUDF01000003_gene185 1.4e-10 71.6 Microbacteriaceae Bacteria 2EHMB@1,2HYGU@201174,33BD3@2,4FQDN@85023 NA|NA|NA MAG.T22.42_01130 1120960.ATXG01000018_gene1362 1.3e-116 426.0 Microbacteriaceae panB GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJP6@201174,4FM52@85023,COG0413@1,COG0413@2 NA|NA|NA H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate MAG.T22.42_01131 1121924.ATWH01000002_gene4046 1.4e-229 802.0 Microbacteriaceae glnA2 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 2GJ2I@201174,4FM01@85023,COG0174@1,COG0174@2 NA|NA|NA E Glutamine synthetase, catalytic domain MAG.T22.42_01132 1120959.ATXF01000001_gene378 0.0 1185.6 Microbacteriaceae glnE GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 ko:K00982 ko00000,ko01000 Bacteria 2GJ91@201174,4FK81@85023,COG1391@1,COG1391@2 NA|NA|NA OT Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell MAG.T22.42_01133 1123052.AUDF01000003_gene189 2.7e-258 897.5 Microbacteriaceae glnA GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 2GMN1@201174,4FMA2@85023,COG0174@1,COG0174@2 NA|NA|NA E Glutamine synthetase, catalytic domain MAG.T22.42_01134 1120960.ATXG01000018_gene1358 3.5e-37 161.0 Microbacteriaceae Bacteria 2IQMG@201174,4FPA3@85023,COG1714@1,COG1714@2 NA|NA|NA S RDD family MAG.T22.42_01135 1120959.ATXF01000001_gene381 6.4e-64 250.8 Microbacteriaceae Bacteria 2AUFS@1,2I87X@201174,2ZA62@2,4FTV7@85023 NA|NA|NA S Domain of unknown function (DUF4191) MAG.T22.42_01136 1001240.GY21_17390 9.8e-151 539.7 Microbacteriaceae lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 R07767,R07768 RC01978 ko00000,ko00001,ko01000 Bacteria 2GKD4@201174,4FKEH@85023,COG0320@1,COG0320@2 NA|NA|NA H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives MAG.T22.42_01137 1120960.ATXG01000018_gene1355 4.3e-75 287.7 Microbacteriaceae lipB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0071944,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 Bacteria 2GJIX@201174,4FM4Z@85023,COG0321@1,COG0321@2 NA|NA|NA H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate MAG.T22.42_01138 1121372.AULK01000001_gene2137 6.8e-07 62.0 Microbacteriaceae Bacteria 2IMKW@201174,4FPE6@85023,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase MAG.T22.42_01139 1120959.ATXF01000001_gene385 3.1e-155 555.1 Microbacteriaceae 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GMUV@201174,4FK9I@85023,COG0508@1,COG0508@2 NA|NA|NA C e3 binding domain MAG.T22.42_01140 1120959.ATXF01000001_gene386 1.8e-211 741.9 Microbacteriaceae lpdA 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GIXY@201174,4FM6P@85023,COG1249@1,COG1249@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain MAG.T22.42_01141 1120959.ATXF01000001_gene388 8.1e-80 303.9 Microbacteriaceae Bacteria 2I3X8@201174,4FMED@85023,COG0438@1,COG0438@2 NA|NA|NA M PAC2 family MAG.T22.42_01142 1120960.ATXG01000018_gene1348 3.6e-167 595.1 Microbacteriaceae sigA GO:0000988,GO:0000990,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 ko:K03086 ko00000,ko03021 Bacteria 2GK3Z@201174,4FK47@85023,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth MAG.T22.42_01143 1120960.ATXG01000018_gene1347 4.8e-142 511.1 Microbacteriaceae murD 3.4.21.10,6.3.2.13,6.3.2.9 ko:K01317,ko:K01925,ko:K01928,ko:K01932 ko00300,ko00471,ko00550,ko01100,map00300,map00471,map00550,map01100 R02783,R02788 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01002,ko01011,ko04131 Bacteria 2GK18@201174,4FMM2@85023,COG0771@1,COG0771@2 NA|NA|NA M Domain of unknown function (DUF1727) MAG.T22.42_01144 1120959.ATXF01000001_gene391 1.7e-67 262.7 Microbacteriaceae cobQ ko:K07009 ko00000 iSB619.SA_RS09800 Bacteria 2GKPV@201174,4FPIE@85023,COG3442@1,COG3442@2 NA|NA|NA S CobB/CobQ-like glutamine amidotransferase domain MAG.T22.42_01145 37919.EP51_34580 1.1e-124 453.0 Nocardiaceae ppk2 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0044237 2.7.4.1 ko:K22468 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2GKRN@201174,4FVD3@85025,COG2326@1,COG2326@2 NA|NA|NA S polyphosphate kinase MAG.T22.42_01146 1001240.GY21_12725 4.3e-19 100.5 Microbacteriaceae Bacteria 2E39Y@1,2GQJA@201174,32Y9G@2,4FQ1H@85023 NA|NA|NA MAG.T22.42_01147 1120959.ATXF01000001_gene393 0.0 1140.6 Microbacteriaceae gyrB2 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 2GM1E@201174,4FMDA@85023,COG0187@1,COG0187@2 NA|NA|NA L TopoisomeraseII MAG.T22.42_01148 1121952.ATXT01000011_gene2893 0.0 1094.3 Microbacteriaceae gyrA GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 2GJ2Q@201174,4FKHF@85023,COG0188@1,COG0188@2 NA|NA|NA L DNA Topoisomerase IV MAG.T22.42_01149 1001240.GY21_12705 5.8e-91 341.3 Microbacteriaceae Bacteria 2GISU@201174,4FMD2@85023,COG1524@1,COG1524@2 NA|NA|NA S Type I phosphodiesterase / nucleotide pyrophosphatase MAG.T22.42_01150 1389489.O159_16140 1.2e-44 186.4 Microbacteriaceae GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 Bacteria 2AN86@1,2HWWU@201174,31D67@2,4FNEF@85023 NA|NA|NA S Protein of unknown function (DUF3043) MAG.T22.42_01151 1451261.AS96_08120 5.1e-137 494.6 Microbacteriaceae argE Bacteria 2GM84@201174,4FKZN@85023,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain MAG.T22.42_01152 1120958.AULD01000009_gene847 1.4e-48 198.7 Microbacteriaceae erpA GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:0071944,GO:1901564 ko:K13628,ko:K15724 ko00000,ko03016 Bacteria 2IHR0@201174,4FNWM@85023,COG0316@1,COG0316@2 NA|NA|NA S Belongs to the HesB IscA family MAG.T22.42_01153 1121924.ATWH01000002_gene4069 2e-106 392.1 Microbacteriaceae ctaC GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 2GNXA@201174,4FK9N@85023,COG1622@1,COG1622@2 NA|NA|NA C Cytochrome C oxidase subunit II, periplasmic domain MAG.T22.42_01154 1120959.ATXF01000001_gene400 1.2e-275 955.3 Microbacteriaceae ctaD GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 Bacteria 2GJHX@201174,4FKNJ@85023,COG0843@1,COG0843@2 NA|NA|NA C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B MAG.T22.42_01155 1389489.O159_16090 2.3e-40 171.8 Microbacteriaceae ctaF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2D9MJ@1,2IFFM@201174,32TTI@2,4FP5D@85023 NA|NA|NA C Belongs to the cytochrome c oxidase bacterial subunit CtaF family MAG.T22.42_01156 243231.GSU0747 3.6e-19 100.5 Proteobacteria Bacteria 1NASK@1224,COG4430@1,COG4430@2 NA|NA|NA S Bacteriocin-protection, YdeI or OmpD-Associated MAG.T22.42_01157 281090.Lxx09820 4.7e-243 847.0 Microbacteriaceae petD GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009512,GO:0009579,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044436,GO:0044459,GO:0044464,GO:0070069,GO:0071944 ko:K00412,ko:K02635,ko:K02637,ko:K03887,ko:K03891,ko:K15879 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 ko00000,ko00001,ko00002,ko00194,ko03029 Bacteria 2GJ1E@201174,4FK3T@85023,COG1290@1,COG1290@2 NA|NA|NA C Cytochrome b(N-terminal)/b6/petB MAG.T22.42_01158 1120960.ATXG01000018_gene1332 1.2e-146 526.2 Microbacteriaceae qcrA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03890,ko:K15878 ko00190,ko01100,map00190,map01100 M00151 ko00000,ko00001,ko00002 iAF987.Gmet_0538 Bacteria 2GIX6@201174,4FKHS@85023,COG0723@1,COG0723@2 NA|NA|NA C Rieske [2Fe-2S] domain MAG.T22.42_01159 1120959.ATXF01000001_gene406 3.1e-107 394.8 Microbacteriaceae qcrC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K00406,ko:K03889 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00151,M00156 ko00000,ko00001,ko00002 3.D.4.3 Bacteria 2GKUB@201174,4FKFX@85023,COG2010@1,COG2010@2 NA|NA|NA C Cytochrome c MAG.T22.42_01160 31964.CMS0698 1.1e-81 309.7 Microbacteriaceae ctaE GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 iJN678.ctaE Bacteria 2GKK8@201174,4FKG9@85023,COG1845@1,COG1845@2 NA|NA|NA C Cytochrome c oxidase subunit III MAG.T22.42_01161 1150399.AQYK01000002_gene2369 7.5e-141 506.9 Microbacteriaceae trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM4G@201174,4FKQ0@85023,COG0547@1,COG0547@2 NA|NA|NA E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) MAG.T22.42_01162 1150399.AQYK01000002_gene3389 9.3e-61 240.7 Microbacteriaceae lipA Bacteria 2HXWT@201174,4FMIM@85023,COG0657@1,COG0657@2 NA|NA|NA I Carboxylesterase family MAG.T22.42_01163 1122609.AUGT01000003_gene2154 3.5e-47 194.9 Propionibacteriales MA20_27460 Bacteria 2GK0N@201174,4DSXI@85009,COG3616@1,COG3616@2 NA|NA|NA E Putative serine dehydratase domain MAG.T22.42_01164 1416759.AYMR01000016_gene3742 5.2e-35 154.5 Microbacteriaceae Bacteria 2H3AT@201174,4FPDD@85023,COG3247@1,COG3247@2 NA|NA|NA S Short repeat of unknown function (DUF308) MAG.T22.42_01165 1120959.ATXF01000004_gene2886 2.4e-96 358.6 Microbacteriaceae Bacteria 2GNX5@201174,4FM1F@85023,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase MAG.T22.42_01166 1121952.ATXT01000011_gene2673 2.7e-55 222.2 Microbacteriaceae glpQ2 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 2GJ5W@201174,4FNKX@85023,COG0584@1,COG0584@2 NA|NA|NA C Glycerophosphoryl diester phosphodiesterase family MAG.T22.42_01167 1121924.ATWH01000006_gene1723 1.6e-126 459.9 Microbacteriaceae lnt ko:K03820 ko00000,ko01000 GT2 Bacteria 2GJ9F@201174,4FMQQ@85023,COG0815@1,COG0815@2 NA|NA|NA M Transfers the fatty acyl group on membrane lipoproteins MAG.T22.42_01168 1416759.AYMR01000016_gene3750 3.2e-304 1050.8 Microbacteriaceae helY GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 ko:K03727 ko00000,ko01000 Bacteria 2GJEX@201174,4FKRU@85023,COG4581@1,COG4581@2 NA|NA|NA L DSHCT MAG.T22.42_01169 1121924.ATWH01000006_gene1725 9.5e-77 293.5 Microbacteriaceae tatC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 ko:K03118 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 2GJK8@201174,4FKUR@85023,COG0805@1,COG0805@2 NA|NA|NA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides MAG.T22.42_01170 1120959.ATXF01000004_gene2878 6.7e-09 66.2 Microbacteriaceae tatA ko:K03116 ko03060,ko03070,map03060,map03070 M00336 ko00000,ko00001,ko00002,ko02044 2.A.64 Bacteria 2HYH0@201174,4FQFI@85023,COG1826@1,COG1826@2 NA|NA|NA U mttA/Hcf106 family MAG.T22.42_01171 1120959.ATXF01000004_gene2877 3.2e-69 268.9 Microbacteriaceae ko:K13573 ko00000,ko03051 Bacteria 2GMAU@201174,4FKSF@85023,COG2378@1,COG2378@2 NA|NA|NA K WYL domain MAG.T22.42_01172 76636.JOEC01000001_gene689 1.1e-75 290.4 Microbacteriaceae ko:K13572,ko:K13573 ko00000,ko03051 Bacteria 2GM46@201174,4FN5T@85023,COG2378@1,COG2378@2 NA|NA|NA K WYL domain MAG.T22.42_01173 1121924.ATWH01000006_gene1730 3.3e-79 302.0 Microbacteriaceae fkbB 5.2.1.8 ko:K01802 ko00000,ko01000 Bacteria 2GJK2@201174,4FNN6@85023,COG0545@1,COG0545@2 NA|NA|NA O Peptidyl-prolyl cis-trans isomerase MAG.T22.42_01174 1416759.AYMR01000016_gene3757 3.3e-141 508.1 Microbacteriaceae trmI GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 ko:K07442 ko00000,ko01000,ko03016 Bacteria 2GJPD@201174,4FKMF@85023,COG2519@1,COG2519@2 NA|NA|NA J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA MAG.T22.42_01175 1151126.AQYI01000004_gene1077 1.3e-60 239.6 Microbacteriaceae 2.1.1.219,2.1.1.220 ko:K07442 ko00000,ko01000,ko03016 Bacteria 2GJNG@201174,4FNF4@85023,COG0637@1,COG0637@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase MAG.T22.42_01176 1120960.ATXG01000002_gene3135 3.6e-91 341.7 Microbacteriaceae ko:K07184 ko00000 Bacteria 2GK10@201174,4FKGP@85023,COG1938@1,COG1938@2 NA|NA|NA S PAC2 family MAG.T22.42_01178 2074.JNYD01000027_gene7360 2.1e-24 118.6 Actinobacteria Bacteria 2E1PZ@1,2ISES@201174,32WD8@2 NA|NA|NA MAG.T22.42_01179 1120959.ATXF01000004_gene2869 1.9e-71 275.8 Microbacteriaceae Bacteria 2GKY8@201174,4FKZE@85023,COG2135@1,COG2135@2 NA|NA|NA S Belongs to the SOS response-associated peptidase family MAG.T22.42_01180 1120959.ATXF01000004_gene2868 4.4e-41 174.9 Microbacteriaceae imuA GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 ko:K14160 ko00000,ko03400 Bacteria 2IIXE@201174,4FP2G@85023,COG4544@1,COG4544@2 NA|NA|NA S Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division MAG.T22.42_01181 1120959.ATXF01000004_gene2867 1.8e-138 499.6 Microbacteriaceae dinB_2 ko:K14161 ko00000,ko03400 Bacteria 2GMZ3@201174,4FKQU@85023,COG0389@1,COG0389@2 NA|NA|NA L impB/mucB/samB family MAG.T22.42_01182 1120959.ATXF01000004_gene2866 0.0 1522.3 Microbacteriaceae dnaE2 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.6,2.7.7.7 ko:K00960,ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJ1P@201174,4FKUX@85023,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase MAG.T22.42_01183 1449058.JQKT01000007_gene1560 8e-114 417.2 Microbacteriaceae Bacteria 2GIZ3@201174,4FKXD@85023,COG1814@1,COG1814@2 NA|NA|NA S VIT family MAG.T22.42_01184 1001240.GY21_20025 2.9e-55 221.5 Microbacteriaceae Bacteria 2GMSR@201174,4FNTE@85023,COG1522@1,COG1522@2 NA|NA|NA K helix_turn_helix ASNC type MAG.T22.42_01185 1120960.ATXG01000002_gene3122 1.3e-241 842.4 Microbacteriaceae sdrA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2GIU5@201174,4FM8J@85023,COG1061@1,COG1061@2 NA|NA|NA L Type III restriction enzyme, res subunit MAG.T22.42_01186 1150399.AQYK01000002_gene2137 2.4e-96 358.6 Microbacteriaceae Bacteria 2GNBP@201174,4FKB1@85023,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase MAG.T22.42_01187 1121924.ATWH01000006_gene1766 3.2e-82 312.4 Microbacteriaceae 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 2GM2X@201174,4FMB7@85023,COG1686@1,COG1686@2 NA|NA|NA M D-alanyl-D-alanine carboxypeptidase MAG.T22.42_01188 1389489.O159_13010 2.7e-90 338.6 Microbacteriaceae spoU2 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 2GJ12@201174,4FKNC@85023,COG0566@1,COG0566@2 NA|NA|NA J SpoU rRNA Methylase family MAG.T22.42_01189 1120960.ATXG01000002_gene3114 1.2e-106 393.3 Microbacteriaceae Bacteria 2GN9W@201174,4FKJJ@85023,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 MAG.T22.42_01190 1120959.ATXF01000004_gene2849 1.4e-82 313.2 Microbacteriaceae Bacteria 2GM96@201174,4FKJW@85023,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 MAG.T22.42_01191 1120959.ATXF01000004_gene2848 1.6e-67 262.7 Microbacteriaceae dnaQ 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2I2KI@201174,4FN64@85023,COG0847@1,COG0847@2 NA|NA|NA L Exonuclease MAG.T22.42_01192 1121372.AULK01000001_gene1968 2.2e-35 154.5 Microbacteriaceae rpmE2 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ4I@201174,4FPKT@85023,COG0254@1,COG0254@2 NA|NA|NA J 50S ribosomal protein L31 type B MAG.T22.42_01193 1123052.AUDF01000003_gene267 5.7e-93 347.4 Microbacteriaceae modF GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21,3.6.3.34 ko:K02013,ko:K02028,ko:K05776 ko02010,map02010 M00189,M00236,M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14,3.A.1.3 Bacteria 2GIXX@201174,4FKXB@85023,COG1119@1,COG1119@2 NA|NA|NA P ATPases associated with a variety of cellular activities MAG.T22.42_01194 1120959.ATXF01000004_gene2843 9.1e-62 243.4 Microbacteriaceae serB 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 Bacteria 2GJDH@201174,4FNGU@85023,COG0560@1,COG0560@2 NA|NA|NA E haloacid dehalogenase-like hydrolase MAG.T22.42_01195 281090.Lxx11740 5.8e-97 360.5 Microbacteriaceae Bacteria 2GK6C@201174,4FKJF@85023,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain MAG.T22.42_01196 1120959.ATXF01000004_gene2841 2.9e-12 77.8 Microbacteriaceae Bacteria 2EGIC@1,2GRS5@201174,33AAH@2,4FQ63@85023 NA|NA|NA S Protein of unknown function (DUF3099) MAG.T22.42_01197 1120960.ATXG01000002_gene3103 1.7e-56 226.5 Microbacteriaceae surf1 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 ko:K14998 ko00000,ko03029 3.D.4.8 Bacteria 2GR90@201174,4FKFS@85023,COG3346@1,COG3346@2 NA|NA|NA S SURF1 family MAG.T22.42_01198 1121952.ATXT01000001_gene1213 1e-28 134.0 Microbacteriaceae Bacteria 2E4WR@1,2IMYV@201174,32ZQT@2,4FPEA@85023 NA|NA|NA MAG.T22.42_01199 1120959.ATXF01000004_gene2838 4.5e-243 847.0 Microbacteriaceae ybiT Bacteria 2GKQ4@201174,4FK4Y@85023,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter MAG.T22.42_01200 258052.JNYV01000001_gene43 4.4e-142 511.5 Actinobacteria pnbA ko:K03929 ko00000,ko01000 CE10 Bacteria 2GJCN@201174,COG2272@1,COG2272@2 NA|NA|NA I Belongs to the type-B carboxylesterase lipase family MAG.T22.42_01201 1416759.AYMR01000004_gene3552 2.7e-71 275.0 Microbacteriaceae Bacteria 2GJUB@201174,4FNH2@85023,COG2353@1,COG2353@2 NA|NA|NA S Belongs to the UPF0312 family MAG.T22.42_01202 1122175.ATXU01000007_gene58 8.2e-23 114.0 Microbacteriaceae Bacteria 2IN7K@201174,4FPDW@85023,COG1280@1,COG1280@2 NA|NA|NA E Sap, sulfolipid-1-addressing protein MAG.T22.42_01203 1144275.COCOR_01788 8.8e-143 513.8 Myxococcales ydaH ko:K12942 ko00000 Bacteria 1MUJ1@1224,2WTR2@28221,2YU56@29,42N8Z@68525,COG2978@1,COG2978@2 NA|NA|NA H AbgT putative transporter family MAG.T22.42_01205 1151122.AQYD01000005_gene3403 4.6e-40 170.6 Microbacteriaceae rsfS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 ko:K00969,ko:K09710 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2IKZ3@201174,4FP5Z@85023,COG0799@1,COG0799@2 NA|NA|NA S Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation MAG.T22.42_01207 1121934.AUDX01000020_gene1504 1.3e-23 116.3 Microbacteriaceae nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2GMFZ@201174,4FMI9@85023,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) MAG.T22.42_01209 1150399.AQYK01000001_gene1850 1.2e-139 503.1 Microbacteriaceae proA GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0293,iNJ661.Rv2427c,iYO844.BSU13130 Bacteria 2GISA@201174,4FKH8@85023,COG0014@1,COG0014@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate MAG.T22.42_01210 1120960.ATXG01000002_gene3083 1.5e-79 302.8 Microbacteriaceae proB GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM8U@201174,4FKUD@85023,COG0263@1,COG0263@2 NA|NA|NA E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate MAG.T22.42_01211 1150399.AQYK01000001_gene1848 9e-228 796.2 Microbacteriaceae obg GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904 ko:K03979 ko00000,ko01000,ko03009 Bacteria 2GISB@201174,4FM26@85023,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control MAG.T22.42_01212 1120958.AULD01000017_gene751 1.9e-37 161.4 Microbacteriaceae rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQDI@201174,4FPIQ@85023,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family MAG.T22.42_01213 1123052.AUDF01000003_gene172 1.2e-38 165.6 Microbacteriaceae rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ9A@201174,4FPBE@85023,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 MAG.T22.42_01214 1120960.ATXG01000002_gene3078 5.3e-234 817.4 Microbacteriaceae rne GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 2GMM5@201174,4FM45@85023,COG1530@1,COG1530@2 NA|NA|NA J Ribonuclease E/G family MAG.T22.42_01215 1121952.ATXT01000011_gene3039 2e-60 238.4 Microbacteriaceae ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 Bacteria 2IFBU@201174,4FNH4@85023,COG0105@1,COG0105@2 NA|NA|NA F NDK MAG.T22.42_01216 1121952.ATXT01000011_gene3040 7.5e-17 93.6 Microbacteriaceae Bacteria 2EHND@1,2GQ7K@201174,33BE5@2,4FPUI@85023 NA|NA|NA S Protein of unknown function (DUF4233) MAG.T22.42_01217 1120959.ATXF01000004_gene2741 4e-123 448.4 Microbacteriaceae folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2447c Bacteria 2GJP2@201174,4FKGZ@85023,COG0285@1,COG0285@2 NA|NA|NA H Mur ligase middle domain MAG.T22.42_01218 1121952.ATXT01000011_gene3042 0.0 1554.3 Microbacteriaceae ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GK9M@201174,4FKJ5@85023,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) MAG.T22.42_01219 1120959.ATXF01000004_gene2734 0.0 1293.1 Microbacteriaceae valS 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GK8H@201174,4FKXW@85023,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner MAG.T22.42_01220 1123052.AUDF01000003_gene163 9e-09 65.9 Microbacteriaceae Bacteria 2B2K3@1,2GY4I@201174,31V5D@2,4FQGU@85023 NA|NA|NA MAG.T22.42_01221 1120960.ATXG01000002_gene3062 6.2e-49 199.9 Microbacteriaceae yitW ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 2IKUH@201174,4FNT6@85023,COG2151@1,COG2151@2 NA|NA|NA S Iron-sulfur cluster assembly protein MAG.T22.42_01222 76636.JOEC01000001_gene649 1.3e-115 422.5 Microbacteriaceae sufC ko:K09013 ko00000,ko02000 Bacteria 2GKB7@201174,4FMJI@85023,COG0396@1,COG0396@2 NA|NA|NA O ATPases associated with a variety of cellular activities MAG.T22.42_01223 1150399.AQYK01000002_gene2159 4.1e-37 160.6 Microbacteriaceae hcaC ko:K05710 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002 Bacteria 2IQK7@201174,4FP2S@85023,COG2146@1,COG2146@2 NA|NA|NA P Rieske-like [2Fe-2S] domain MAG.T22.42_01224 1120959.ATXF01000004_gene2726 5e-154 550.8 Microbacteriaceae sufD GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136 ko:K09015 ko00000 iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144 Bacteria 2GJNV@201174,4FKS2@85023,COG0719@1,COG0719@2 NA|NA|NA O Uncharacterized protein family (UPF0051) MAG.T22.42_01225 1121372.AULK01000001_gene1982 6.8e-254 882.9 Microbacteriaceae sufB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 ko:K07033,ko:K09014 ko00000 Bacteria 2GKCZ@201174,4FM34@85023,COG0719@1,COG0719@2 NA|NA|NA O Uncharacterized protein family (UPF0051) MAG.T22.42_01226 273677.BW34_00130 2.8e-88 332.0 Microbacteriaceae ctaA ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 Bacteria 2GJQX@201174,4FNAP@85023,COG1612@1,COG1612@2 NA|NA|NA O Cytochrome oxidase assembly protein MAG.T22.42_01227 1120959.ATXF01000004_gene2722 9.1e-127 459.9 Microbacteriaceae ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Bacteria 2GJMY@201174,4FM53@85023,COG0109@1,COG0109@2 NA|NA|NA O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group MAG.T22.42_01228 1416752.AYME01000003_gene3035 0.0 1104.4 Microbacteriaceae tkt 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ1K@201174,4FM21@85023,COG0021@1,COG0021@2 NA|NA|NA G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate MAG.T22.42_01229 1120960.ATXG01000002_gene3053 3.1e-137 495.0 Microbacteriaceae tal 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMF9@201174,4FMAB@85023,COG0176@1,COG0176@2 NA|NA|NA G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway MAG.T22.42_01230 1120959.ATXF01000004_gene2719 7.5e-209 733.4 Microbacteriaceae tal 2.2.1.2,5.3.1.9 ko:K01810,ko:K13810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00004,M00007,M00114 R01827,R02739,R02740,R03321 RC00376,RC00439,RC00563,RC00604 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2HS9W@201174,4FMGK@85023,COG0166@1,COG0166@2 NA|NA|NA G Belongs to the GPI family MAG.T22.42_01231 1120959.ATXF01000004_gene2718 1e-263 915.6 Microbacteriaceae zwf 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 iIT341.HP1101 Bacteria 2GISI@201174,4FKKW@85023,COG0364@1,COG0364@2 NA|NA|NA G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone MAG.T22.42_01232 1416759.AYMR01000052_gene3849 3.6e-102 378.3 Microbacteriaceae opcA Bacteria 2GJ1H@201174,4FKEB@85023,COG3429@1,COG3429@2 NA|NA|NA G Glucose-6-phosphate dehydrogenase subunit MAG.T22.42_01233 312284.A20C1_02801 1.9e-50 206.1 unclassified Actinobacteria (class) pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 ko:K01057,ko:K02003 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008,M00258 R02035 RC00537 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1 Bacteria 2GMQ2@201174,3UX0J@52018,COG0363@1,COG0363@2 NA|NA|NA G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase MAG.T22.42_01234 979556.MTES_3657 8.8e-49 199.5 Microbacteriaceae rbpA Bacteria 2CNY9@1,2IKKZ@201174,31GEE@2,4FP7Z@85023 NA|NA|NA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters MAG.T22.42_01235 1120959.ATXF01000004_gene2714 1.6e-28 131.7 Microbacteriaceae secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2GR31@201174,4FQC7@85023,COG1314@1,COG1314@2 NA|NA|NA U Preprotein translocase SecG subunit MAG.T22.42_01236 31964.CMS1986 1.6e-103 382.5 Microbacteriaceae tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJXZ@201174,4FKEV@85023,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) MAG.T22.42_01237 1120959.ATXF01000004_gene2712 1.7e-165 589.0 Microbacteriaceae pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJC6@201174,4FKHB@85023,COG0126@1,COG0126@2 NA|NA|NA G Belongs to the phosphoglycerate kinase family MAG.T22.42_01238 1150399.AQYK01000002_gene2176 3.3e-146 524.6 Microbacteriaceae gap GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2GJK4@201174,4FM64@85023,COG0057@1,COG0057@2 NA|NA|NA G Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain MAG.T22.42_01239 1120960.ATXG01000002_gene3043 1.3e-100 372.5 Microbacteriaceae sodA 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Bacteria 2GJV8@201174,4FMBN@85023,COG0605@1,COG0605@2 NA|NA|NA P Destroys radicals which are normally produced within the cells and which are toxic to biological systems MAG.T22.42_01240 1416759.AYMR01000052_gene3857 1.1e-130 473.0 Microbacteriaceae whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 ko:K09762 ko00000 Bacteria 2GJZU@201174,4FKP0@85023,COG1481@1,COG1481@2 NA|NA|NA K May be required for sporulation MAG.T22.42_01241 1120960.ATXG01000002_gene3041 4.9e-114 417.5 Microbacteriaceae rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K06958 ko00000,ko03019 Bacteria 2GMWB@201174,4FKSJ@85023,COG1660@1,COG1660@2 NA|NA|NA S Displays ATPase and GTPase activities MAG.T22.42_01242 1120959.ATXF01000004_gene2707 2.2e-223 781.9 Microbacteriaceae uvrC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GIS4@201174,4FKM6@85023,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision MAG.T22.42_01243 1121372.AULK01000001_gene2000 0.0 1575.5 Microbacteriaceae uvrA GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090 ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GJUV@201174,4FKQD@85023,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate MAG.T22.42_01244 1120959.ATXF01000004_gene2705 0.0 1127.5 Microbacteriaceae uvrB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GJ03@201174,4FK6U@85023,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage MAG.T22.42_01245 1120959.ATXF01000004_gene2704 2.2e-49 202.2 Microbacteriaceae coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN96@201174,4FNR9@85023,COG0237@1,COG0237@2 NA|NA|NA H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A MAG.T22.42_01246 1120960.ATXG01000002_gene3035 2.4e-230 804.7 Microbacteriaceae rpsA ko:K02945 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJAK@201174,4FK48@85023,COG0539@1,COG0539@2 NA|NA|NA J Ribosomal protein S1-like RNA-binding domain MAG.T22.42_01247 1121924.ATWH01000006_gene1815 2.9e-295 1021.1 Microbacteriaceae polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 2GJY2@201174,4FK5U@85023,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity MAG.T22.42_01248 1451261.AS96_10895 1.5e-47 195.7 Microbacteriaceae ydiI Bacteria 2IKTU@201174,4FNXG@85023,COG2050@1,COG2050@2 NA|NA|NA Q Thioesterase superfamily MAG.T22.42_01249 1122238.AULR01000002_gene605 7.9e-81 306.6 Microbacteriaceae pdtaR GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 ko:K22010 M00839 ko00000,ko00002,ko02022 Bacteria 2GK7T@201174,4FKD0@85023,COG3707@1,COG3707@2 NA|NA|NA T ANTAR MAG.T22.42_01251 1121924.ATWH01000006_gene1821 9.1e-214 749.6 Microbacteriaceae pyk GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740 Bacteria 2GJY8@201174,4FKS6@85023,COG0469@1,COG0469@2 NA|NA|NA G Pyruvate kinase, alpha/beta domain MAG.T22.42_01252 1120959.ATXF01000004_gene2696 3.3e-227 794.3 Microbacteriaceae gltD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450 Bacteria 2GJ0A@201174,4FKHC@85023,COG0493@1,COG0493@2 NA|NA|NA E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster MAG.T22.42_01253 1150399.AQYK01000002_gene2213 0.0 2436.0 Microbacteriaceae gltB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 Bacteria 2GN09@201174,4FK7H@85023,COG0067@1,COG0067@2,COG0069@1,COG0069@2,COG0070@1,COG0070@2 NA|NA|NA E GXGXG motif MAG.T22.42_01254 1121924.ATWH01000006_gene1824 2.1e-109 402.1 Microbacteriaceae lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 2GKSS@201174,4FKKF@85023,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins MAG.T22.42_01255 1120959.ATXF01000004_gene2693 9.5e-93 346.7 Microbacteriaceae trpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN6T@201174,4FKQN@85023,COG0159@1,COG0159@2 NA|NA|NA E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate MAG.T22.42_01256 1121924.ATWH01000006_gene1826 1.2e-187 662.5 Microbacteriaceae trpB GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM7Z@201174,4FKK8@85023,COG0133@1,COG0133@2 NA|NA|NA E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine MAG.T22.42_01257 1151122.AQYD01000005_gene3179 4.1e-88 331.3 Microbacteriaceae trpC 4.1.1.48,4.2.1.20 ko:K01609,ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03508 RC00209,RC00210,RC00700,RC00701,RC00944,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIVV@201174,4FKAV@85023,COG0134@1,COG0134@2 NA|NA|NA E Indole-3-glycerol phosphate synthase MAG.T22.42_01258 450380.JPSY01000003_gene2543 3e-18 97.4 Bacteria Bacteria 290XR@1,2ZNJH@2 NA|NA|NA MAG.T22.42_01259 1449058.JQKT01000007_gene1514 1.3e-11 76.6 Microbacteriaceae Bacteria 2EGC7@1,2HSQW@201174,33A40@2,4FPXY@85023 NA|NA|NA S Tryptophan-associated transmembrane protein (Trp_oprn_chp) MAG.T22.42_01260 1121372.AULK01000001_gene2046 2.1e-192 678.7 Microbacteriaceae trpE 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKJT@201174,4FKCV@85023,COG0147@1,COG0147@2 NA|NA|NA EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia MAG.T22.42_01261 76636.JOEC01000001_gene775 8e-37 159.8 Microbacteriaceae hisI GO:0008150,GO:0040007 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1606 Bacteria 2IKKU@201174,4FP35@85023,COG0139@1,COG0139@2 NA|NA|NA E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP MAG.T22.42_01262 1416759.AYMR01000002_gene1795 5.9e-103 380.6 Microbacteriaceae hisF GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007 4.1.3.27 ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023,M00026 R00985,R00986,R04558 RC00010,RC01190,RC01943,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIRP@201174,4FKWV@85023,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit MAG.T22.42_01263 1120960.ATXG01000002_gene3016 8.1e-114 416.8 Microbacteriaceae hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNAX@201174,4FKI0@85023,COG0040@1,COG0040@2 NA|NA|NA E ATP phosphoribosyltransferase MAG.T22.42_01264 1451261.AS96_10820 2.3e-30 137.9 Microbacteriaceae hisE GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04640 RC00002,RC00945,RC01055 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iSB619.SA_RS14110,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186,iYO844.BSU34860 Bacteria 2IQ4D@201174,4FPHQ@85023,COG0140@1,COG0140@2 NA|NA|NA E phosphoribosyl-ATP diphosphatase activity MAG.T22.42_01265 1451261.AS96_10815 4.8e-85 320.9 Microbacteriaceae rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJZ9@201174,4FKYZ@85023,COG0036@1,COG0036@2 NA|NA|NA G Ribulose-phosphate 3 epimerase family MAG.T22.42_01266 1416759.AYMR01000002_gene1791 1.6e-124 453.0 Microbacteriaceae sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176,5.3.1.9 ko:K01810,ko:K03500 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 2GM21@201174,4FMK7@85023,COG0144@1,COG0144@2,COG0781@1,COG0781@2 NA|NA|NA JK Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family MAG.T22.42_01267 1278308.KB907074_gene749 1.4e-76 293.1 Microbacteriaceae fmt GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.1.176,2.1.2.9 ko:K00604,ko:K03500 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000,ko03009 iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048 Bacteria 2GKH5@201174,4FM1U@85023,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus MAG.T22.42_01268 1120959.ATXF01000004_gene2678 4.7e-157 561.6 Microbacteriaceae priA ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKES@201174,4FMXJ@85023,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA MAG.T22.42_01269 1001240.GY21_05815 4.8e-168 597.4 Microbacteriaceae metK 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ4U@201174,4FK84@85023,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme MAG.T22.42_01270 76636.JOEC01000001_gene738 8.6e-103 380.6 Microbacteriaceae coaBC GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJGJ@201174,4FK95@85023,COG0452@1,COG0452@2 NA|NA|NA H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine MAG.T22.42_01271 1121924.ATWH01000006_gene1841 6.9e-32 142.9 Microbacteriaceae rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2IQHU@201174,4FPHE@85023,COG1758@1,COG1758@2 NA|NA|NA K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits MAG.T22.42_01272 1120959.ATXF01000004_gene2674 1.1e-98 366.7 Microbacteriaceae gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 ko:K00942,ko:K01591 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00050,M00051 R00332,R00965,R02090 RC00002,RC00409 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2813,iIT341.HP0321,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Bacteria 2GK2M@201174,4FKKJ@85023,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP MAG.T22.42_01273 1120959.ATXF01000004_gene2673 8.8e-84 317.0 Microbacteriaceae pyrF GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS17585 Bacteria 2GKWK@201174,4FKPC@85023,COG0284@1,COG0284@2 NA|NA|NA F Orotidine 5'-phosphate decarboxylase / HUMPS family MAG.T22.42_01274 1120960.ATXG01000002_gene3005 0.0 1823.1 Microbacteriaceae carB GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041 Bacteria 2GK5N@201174,4FKI2@85023,COG0458@1,COG0458@2 NA|NA|NA EF carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity MAG.T22.42_01275 1120959.ATXF01000004_gene2671 9e-175 619.8 Microbacteriaceae carA GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1950,iNJ661.Rv1383,iUTI89_1310.UTI89_C0036,iYO844.BSU15510,ic_1306.c0040 Bacteria 2GKFA@201174,4FK6A@85023,COG0505@1,COG0505@2 NA|NA|NA EF Carbamoyl-phosphate synthase small chain, CPSase domain MAG.T22.42_01276 1121372.AULK01000001_gene2064 8.1e-172 610.1 Microbacteriaceae pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ0T@201174,4FKCT@85023,COG0044@1,COG0044@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily MAG.T22.42_01277 1120960.ATXG01000002_gene3001 5e-131 474.2 Microbacteriaceae pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15490 Bacteria 2GKNA@201174,4FKCB@85023,COG0540@1,COG0540@2 NA|NA|NA F Belongs to the ATCase OTCase family MAG.T22.42_01278 1348338.ADILRU_1543 6.5e-56 223.8 Microbacteriaceae pyrR GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 iHN637.CLJU_RS05275 Bacteria 2GJNP@201174,4FNED@85023,COG2065@1,COG2065@2 NA|NA|NA F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant MAG.T22.42_01280 714083.JH370377_gene2005 1.5e-41 175.6 Microbacteriaceae nusB GO:0008150,GO:0040007 ko:K03625 ko00000,ko03009,ko03021 Bacteria 2IM3D@201174,4FNSQ@85023,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons MAG.T22.42_01281 1120960.ATXG01000002_gene2998 1e-91 342.8 Microbacteriaceae efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 2GJMS@201174,4FM9Y@85023,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase MAG.T22.42_01282 1120960.ATXG01000002_gene2997 1.6e-52 212.2 Microbacteriaceae aroQ GO:0003674,GO:0003824,GO:0003855,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 iIT341.HP1038 Bacteria 2IMBY@201174,4FP89@85023,COG0757@1,COG0757@2 NA|NA|NA E Catalyzes a trans-dehydration via an enolate intermediate MAG.T22.42_01283 1177594.MIC448_1100046 1.5e-117 429.9 Microbacteriaceae dinF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03327 ko00000,ko02000 2.A.66.1 Bacteria 2GJE3@201174,4FMF6@85023,COG0534@1,COG0534@2 NA|NA|NA V MatE MAG.T22.42_01284 1120959.ATXF01000004_gene2660 1.8e-95 355.5 Microbacteriaceae aroB GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIUZ@201174,4FKA2@85023,COG0337@1,COG0337@2 NA|NA|NA E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) MAG.T22.42_01285 1120958.AULD01000010_gene2383 3.7e-16 89.7 Microbacteriaceae tuf GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 ko:K02358 ko00000,ko03012,ko03029,ko04147 Bacteria 2GK4T@201174,4FMHN@85023,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis MAG.T22.42_01286 1123251.ATWM01000001_gene900 1.3e-67 263.1 Intrasporangiaceae czcD ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 2GMRZ@201174,4FEH3@85021,COG1230@1,COG1230@2 NA|NA|NA P cation transporter MAG.T22.42_01287 1120959.ATXF01000004_gene2440 5.7e-86 324.3 Microbacteriaceae Bacteria 2I5A8@201174,4FM0F@85023,COG4117@1,COG4117@2 NA|NA|NA C Prokaryotic cytochrome b561 MAG.T22.42_01288 281090.Lxx20340 3.3e-49 200.7 Microbacteriaceae rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02946 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHRA@201174,4FP1M@85023,COG0051@1,COG0051@2 NA|NA|NA J Involved in the binding of tRNA to the ribosomes MAG.T22.42_01289 1121924.ATWH01000001_gene4138 6.2e-101 373.6 Microbacteriaceae rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 ko:K02906 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJXT@201174,4FMF8@85023,COG0087@1,COG0087@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit MAG.T22.42_01290 1120960.ATXG01000012_gene3743 7.2e-78 297.0 Microbacteriaceae rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02926 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJYJ@201174,4FKD3@85023,COG0088@1,COG0088@2 NA|NA|NA J Forms part of the polypeptide exit tunnel MAG.T22.42_01291 1123052.AUDF01000002_gene594 1.5e-41 175.3 Microbacteriaceae rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02892 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ7V@201174,4FP7F@85023,COG0089@1,COG0089@2 NA|NA|NA J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome MAG.T22.42_01292 1121924.ATWH01000001_gene4135 9.8e-152 542.7 Microbacteriaceae rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02886 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GK7R@201174,4FKJ7@85023,COG0090@1,COG0090@2 NA|NA|NA J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity MAG.T22.42_01293 1194165.CAJF01000030_gene173 1.2e-45 188.7 Microbacteriaceae rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02965 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKMS@201174,4FP2Y@85023,COG0185@1,COG0185@2 NA|NA|NA J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA MAG.T22.42_01294 1123052.AUDF01000002_gene591 5e-52 210.3 Microbacteriaceae rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IM3J@201174,4FNXV@85023,COG0091@1,COG0091@2 NA|NA|NA J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome MAG.T22.42_01295 1120959.ATXF01000007_gene2107 3.8e-115 421.0 Microbacteriaceae rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02982 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GKF1@201174,4FKIV@85023,COG0092@1,COG0092@2 NA|NA|NA J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation MAG.T22.42_01296 1150399.AQYK01000002_gene2986 2.9e-72 277.7 Microbacteriaceae rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02878 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFEI@201174,4FNDC@85023,COG0197@1,COG0197@2 NA|NA|NA J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs MAG.T22.42_01297 1122237.AUGQ01000005_gene1470 1e-29 136.0 Microbacteriaceae rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02904 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ6V@201174,4FP59@85023,COG0255@1,COG0255@2 NA|NA|NA J Ribosomal L29 protein MAG.T22.42_01298 1120959.ATXF01000007_gene2110 4.5e-36 157.5 Microbacteriaceae rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02961 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ68@201174,4FP9J@85023,COG0186@1,COG0186@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA MAG.T22.42_01299 1001240.GY21_00980 4.7e-58 230.3 Microbacteriaceae rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02874 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHNX@201174,4FNQS@85023,COG0093@1,COG0093@2 NA|NA|NA J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome MAG.T22.42_01300 1150399.AQYK01000002_gene2982 1.7e-52 211.8 Microbacteriaceae rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02895 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKP2@201174,4FNQD@85023,COG0198@1,COG0198@2 NA|NA|NA J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit MAG.T22.42_01301 76636.JOEC01000002_gene2166 1.6e-87 328.9 Microbacteriaceae rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02931 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJW7@201174,4FKHV@85023,COG0094@1,COG0094@2 NA|NA|NA J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits MAG.T22.42_01302 1120959.ATXF01000007_gene2114 3.4e-62 244.2 Microbacteriaceae rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02994 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHQZ@201174,4FNTW@85023,COG0096@1,COG0096@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit MAG.T22.42_01303 1120960.ATXG01000012_gene3730 1.3e-77 295.8 Microbacteriaceae rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02933 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GK35@201174,4FKG8@85023,COG0097@1,COG0097@2 NA|NA|NA J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center MAG.T22.42_01304 1120959.ATXF01000007_gene2116 2.5e-48 198.0 Microbacteriaceae rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02881 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKTX@201174,4FNV4@85023,COG0256@1,COG0256@2 NA|NA|NA J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance MAG.T22.42_01305 1120959.ATXF01000007_gene2117 8.9e-88 330.1 Microbacteriaceae rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02988 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJW8@201174,4FKFF@85023,COG0098@1,COG0098@2 NA|NA|NA J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body MAG.T22.42_01306 1177594.MIC448_1620029 1.9e-20 104.4 Microbacteriaceae rpmD GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02907 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQV0@201174,4FPZV@85023,COG1841@1,COG1841@2 NA|NA|NA J structural constituent of ribosome MAG.T22.42_01307 1150399.AQYK01000002_gene2975 4.4e-58 231.5 Microbacteriaceae rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02876 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2II6M@201174,4FKEE@85023,COG0200@1,COG0200@2 NA|NA|NA J Binds to the 23S rRNA MAG.T22.42_01308 1120959.ATXF01000007_gene2120 1e-203 716.1 Microbacteriaceae secY GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 2GJ26@201174,4FKES@85023,COG0201@1,COG0201@2 NA|NA|NA U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently MAG.T22.42_01309 1001240.GY21_01030 1.9e-69 268.9 Microbacteriaceae adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJ7T@201174,4FNDD@85023,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism MAG.T22.42_01310 1121017.AUFG01000021_gene2258 3.2e-33 147.5 Intrasporangiaceae infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009986,GO:0016020,GO:0030246,GO:0030247,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 2IQ4B@201174,4FHB2@85021,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex MAG.T22.42_01311 1283287.KB822575_gene119 8.2e-14 81.6 Propionibacteriales rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GWMH@201174,4DSPP@85009,COG0257@1,COG0257@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL36 family MAG.T22.42_01312 1120959.ATXF01000007_gene2125 1.1e-54 219.2 Microbacteriaceae rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHPN@201174,4FNVJ@85023,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits MAG.T22.42_01313 1121924.ATWH01000001_gene4106 1.4e-63 248.8 Microbacteriaceae rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFFC@201174,4FNCF@85023,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome MAG.T22.42_01314 1120960.ATXG01000012_gene3711 2.8e-166 591.3 Microbacteriaceae rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2GJJ5@201174,4FM7X@85023,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates MAG.T22.42_01315 1151122.AQYD01000006_gene1808 8.3e-55 220.3 Microbacteriaceae rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 ko:K02879 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHV2@201174,4FNFS@85023,COG0203@1,COG0203@2 NA|NA|NA J structural constituent of ribosome MAG.T22.42_01316 1121952.ATXT01000015_gene197 1.4e-78 299.7 Microbacteriaceae truA GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 2GJ6C@201174,4FMRF@85023,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs MAG.T22.42_01317 1120960.ATXG01000012_gene3707 8e-68 263.1 Microbacteriaceae rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFG1@201174,4FNCQ@85023,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly MAG.T22.42_01318 1120960.ATXG01000012_gene3706 1.1e-59 236.1 Microbacteriaceae rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GNDY@201174,4FNCJ@85023,COG0103@1,COG0103@2 NA|NA|NA J structural constituent of ribosome MAG.T22.42_01319 1120960.ATXG01000012_gene3705 7.3e-189 666.8 Microbacteriaceae glmM GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 R02060 RC00408 ko00000,ko00001,ko01000 iAF987.Gmet_1886,iLJ478.TM0184,iSB619.SA_RS11275,iSBO_1134.SBO_3206 Bacteria 2GN87@201174,4FMBU@85023,COG1109@1,COG1109@2 NA|NA|NA G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate MAG.T22.42_01320 1150399.AQYK01000002_gene2955 1.7e-120 439.1 Microbacteriaceae coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_3838,iECH74115_1262.ECH74115_5439,iECSE_1348.ECSE_4265,iECSF_1327.ECSF_3833,iECSP_1301.ECSP_5045,iECW_1372.ECW_m4332,iEcDH1_1363.EcDH1_4016,iEcolC_1368.EcolC_4046,iPC815.YPO3758,iSFV_1184.SFV_4047,iSFxv_1172.SFxv_4418,iWFL_1372.ECW_m4332,iZ_1308.Z5545 Bacteria 2GIRR@201174,4FK76@85023,COG1072@1,COG1072@2 NA|NA|NA H pantothenate kinase activity MAG.T22.42_01321 1121924.ATWH01000010_gene836 1.2e-263 915.6 Microbacteriaceae glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iNJ661.Rv3436c,iSB619.SA_RS11245,iYO844.BSU01780 Bacteria 2GKH0@201174,4FKZM@85023,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source MAG.T22.42_01322 1385518.N798_09620 1.5e-29 135.6 Intrasporangiaceae acpS GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.8.7,3.2.1.52 ko:K00997,ko:K01207 ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501 M00628 R00022,R01625,R05963,R07809,R07810,R10831 RC00002,RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 2IQF6@201174,4FHAC@85021,COG0736@1,COG0736@2 NA|NA|NA I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein MAG.T22.42_01323 1121924.ATWH01000010_gene838 1.5e-94 353.2 Microbacteriaceae alr GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008784,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0019842,GO:0030170,GO:0030203,GO:0034645,GO:0036094,GO:0036361,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0048037,GO:0050662,GO:0070279,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011 iEC55989_1330.EC55989_1285,iECIAI39_1322.ECIAI39_1880,iECO103_1326.ECO103_1292,iECO26_1355.ECO26_1703,iECSE_1348.ECSE_1238,iECUMN_1333.ECUMN_1479,iECW_1372.ECW_m1275,iEKO11_1354.EKO11_2666,iEcE24377_1341.EcE24377A_1335,iPC815.YPO0321,iSBO_1134.SBO_4064,iSbBS512_1146.SbBS512_E4542,iWFL_1372.ECW_m1275,iYL1228.KPN_02308,iYL1228.KPN_04440 Bacteria 2GM2Y@201174,4FKMQ@85023,COG0787@1,COG0787@2 NA|NA|NA M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids MAG.T22.42_01324 1389489.O159_05360 3.3e-51 208.0 Microbacteriaceae ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.1.221,5.1.1.1 ko:K01775,ko:K06925,ko:K07102 ko00473,ko00520,ko01100,ko01502,map00473,map00520,map01100,map01502 R00401,R08968,R11024 RC00002,RC00078,RC00285 ko00000,ko00001,ko01000,ko01011,ko03016 Bacteria 2IKV2@201174,4FNTQ@85023,COG0802@1,COG0802@2 NA|NA|NA S Threonylcarbamoyl adenosine biosynthesis protein TsaE MAG.T22.42_01325 1121372.AULK01000005_gene1720 2.9e-41 175.3 Microbacteriaceae yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 2GMTM@201174,4FNN1@85023,COG1214@1,COG1214@2 NA|NA|NA O Glycoprotease family MAG.T22.42_01326 1121952.ATXT01000015_gene185 2.9e-36 158.3 Microbacteriaceae rimI GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.3.1.128,2.3.1.234 ko:K01409,ko:K03789,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03009,ko03016 Bacteria 2IM9R@201174,4FPUS@85023,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain MAG.T22.42_01327 1150399.AQYK01000002_gene2948 4.4e-149 534.3 Microbacteriaceae tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 2GJ98@201174,4FKR0@85023,COG0533@1,COG0533@2 NA|NA|NA O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction MAG.T22.42_01329 281090.Lxx19890 6.4e-101 374.4 Microbacteriaceae Bacteria 2GK97@201174,4FMAM@85023,COG2265@1,COG2265@2 NA|NA|NA J COG0500 SAM-dependent methyltransferases MAG.T22.42_01330 1120959.ATXF01000007_gene2145 4.5e-43 180.3 Microbacteriaceae groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K04078 ko00000,ko03029,ko03110 Bacteria 2IKTH@201174,4FP1U@85023,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter MAG.T22.42_01331 1416759.AYMR01000007_gene831 1.4e-93 349.7 Microbacteriaceae rarD ko:K05786 ko00000,ko02000 2.A.7.7 Bacteria 2GKCP@201174,4FK4U@85023,COG2962@1,COG2962@2 NA|NA|NA S EamA-like transporter family MAG.T22.42_01332 1001240.GY21_20630 6.7e-152 543.9 Microbacteriaceae natB ko:K01999,ko:K11954 ko02010,ko02024,map02010,map02024 M00237,M00322 ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.2,3.A.1.4.6 Bacteria 2GM00@201174,4FMUU@85023,COG0683@1,COG0683@2 NA|NA|NA E Receptor family ligand binding region MAG.T22.42_01333 1120960.ATXG01000012_gene3689 4.5e-116 424.1 Microbacteriaceae livF ko:K01996,ko:K11958 ko02010,ko02024,map02010,map02024 M00237,M00322 ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.2,3.A.1.4.6 Bacteria 2GKSQ@201174,4FM4E@85023,COG0410@1,COG0410@2 NA|NA|NA E ATPases associated with a variety of cellular activities MAG.T22.42_01334 1120960.ATXG01000012_gene3688 3.1e-127 461.5 Microbacteriaceae natA ko:K01995,ko:K11957 ko02010,ko02024,map02010,map02024 M00237,M00322 ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.2,3.A.1.4.6 Bacteria 2GMEE@201174,4FMP0@85023,COG0411@1,COG0411@2 NA|NA|NA E Branched-chain amino acid ATP-binding cassette transporter MAG.T22.42_01335 1120960.ATXG01000012_gene3687 8.9e-120 436.8 Microbacteriaceae livM ko:K01998,ko:K11955 ko02010,ko02024,map02010,map02024 M00237,M00322 ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.2,3.A.1.4.6 Bacteria 2GJB3@201174,4FMMG@85023,COG4177@1,COG4177@2 NA|NA|NA E Belongs to the binding-protein-dependent transport system permease family MAG.T22.42_01336 1120960.ATXG01000012_gene3686 1.7e-150 539.3 Microbacteriaceae ko:K01997,ko:K11956 ko02010,ko02024,map02010,map02024 M00237,M00322 ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.2,3.A.1.4.6 Bacteria 2GMAY@201174,4FK82@85023,COG0559@1,COG0559@2 NA|NA|NA E Branched-chain amino acid transport system / permease component MAG.T22.42_01337 1121924.ATWH01000010_gene856 2.1e-229 801.6 Microbacteriaceae guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GITZ@201174,4FKA6@85023,COG0516@1,COG0516@2,COG0517@1,COG0517@2 NA|NA|NA F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth MAG.T22.42_01341 1120960.ATXG01000012_gene3682 2.1e-165 588.6 Microbacteriaceae guaB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GKVS@201174,4FM0J@85023,COG0516@1,COG0516@2 NA|NA|NA F IMP dehydrogenase / GMP reductase domain MAG.T22.42_01342 1120959.ATXF01000007_gene2157 2.7e-55 222.2 Microbacteriaceae surf1 ko:K14998 ko00000,ko03029 3.D.4.8 Bacteria 2GMGB@201174,4FNCG@85023,COG3346@1,COG3346@2 NA|NA|NA S SURF1 family MAG.T22.42_01343 1120960.ATXG01000012_gene3675 6.3e-38 163.7 Microbacteriaceae GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 2E65S@1,2IMEQ@201174,330UF@2,4FP9U@85023 NA|NA|NA S Domain of unknown function (DUF3817) MAG.T22.42_01344 1449058.JQKT01000013_gene315 1.9e-257 894.8 Microbacteriaceae guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833 Bacteria 2GM09@201174,4FK6T@85023,COG0518@1,COG0518@2,COG0519@1,COG0519@2 NA|NA|NA F Catalyzes the synthesis of GMP from XMP MAG.T22.42_01345 529884.Rhola_00012660 8.6e-39 167.2 Microbacteriaceae narL ko:K07684 ko02020,map02020 M00471 ko00000,ko00001,ko00002,ko02022 Bacteria 2HSNY@201174,4FPMD@85023,COG2197@1,COG2197@2 NA|NA|NA KT helix_turn_helix, Lux Regulon MAG.T22.42_01346 529884.Rhola_00002480 9.2e-19 102.1 Microbacteriaceae Bacteria 2GWSQ@201174,4FQRQ@85023,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase MAG.T22.42_01347 1120960.ATXG01000014_gene563 1.7e-65 256.1 Microbacteriaceae ko:K06377 ko00000 Bacteria 2GNCK@201174,4FM9W@85023,COG4760@1,COG4760@2 NA|NA|NA S Bax inhibitor 1 like MAG.T22.42_01348 1123052.AUDF01000002_gene525 3.6e-70 271.9 Microbacteriaceae glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 2GM8K@201174,4FMC9@85023,COG0584@1,COG0584@2 NA|NA|NA C Glycerophosphoryl diester phosphodiesterase family MAG.T22.42_01349 1120960.ATXG01000014_gene561 0.0 1229.5 Microbacteriaceae pcrA GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GISS@201174,4FMT2@85023,COG0210@1,COG0210@2 NA|NA|NA L UvrD-like helicase C-terminal domain MAG.T22.42_01350 1001240.GY21_19555 2.7e-106 392.5 Microbacteriaceae Bacteria 2GKWX@201174,4FNJK@85023,COG4097@1,COG4097@2 NA|NA|NA P Ferric reductase like transmembrane component MAG.T22.42_01351 312284.A20C1_10971 3e-13 80.9 Actinobacteria Bacteria 2GTTI@201174,COG3976@1,COG3976@2 NA|NA|NA S FMN-binding domain protein MAG.T22.42_01352 1410634.JHVD01000007_gene1006 2.1e-41 176.0 Actinobacteria apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 2GN6F@201174,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein MAG.T22.42_01353 1206741.BAFX01000042_gene3043 4.3e-68 264.6 Nocardiaceae Bacteria 2GIZ3@201174,4FW5U@85025,COG1814@1,COG1814@2 NA|NA|NA S VIT family MAG.T22.42_01354 1120959.ATXF01000007_gene2167 3.7e-176 624.4 Microbacteriaceae sucC 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKSB@201174,4FM6N@85023,COG0045@1,COG0045@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit MAG.T22.42_01355 1120959.ATXF01000007_gene2168 2.3e-146 525.0 Microbacteriaceae sucD GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK00@201174,4FK7C@85023,COG0074@1,COG0074@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit MAG.T22.42_01356 1120960.ATXG01000014_gene555 2.5e-31 142.1 Microbacteriaceae Bacteria 2DXS3@1,2GV4K@201174,3468X@2,4FQEH@85023 NA|NA|NA MAG.T22.42_01357 1120960.ATXG01000014_gene554 2.4e-83 316.2 Microbacteriaceae Bacteria 28MY8@1,2I3GD@201174,2ZEEV@2,4FTRZ@85023 NA|NA|NA MAG.T22.42_01358 1121924.ATWH01000010_gene897 1.8e-74 286.6 Microbacteriaceae Bacteria 2I39E@201174,4FMNT@85023,COG3266@1,COG3266@2 NA|NA|NA S domain, Protein MAG.T22.42_01359 1120959.ATXF01000007_gene2174 9.9e-74 283.1 Microbacteriaceae purN GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0034641,GO:0042558,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0071704,GO:1901360,GO:1901564 2.1.2.2,2.1.2.3,3.5.4.10 ko:K00602,ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04325,R04326,R04560 RC00026,RC00197,RC00263,RC00456,RC01128 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2H8QB@201174,4FKBW@85023,COG0299@1,COG0299@2 NA|NA|NA F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate MAG.T22.42_01360 76636.JOEC01000002_gene2265 3.3e-209 734.6 Microbacteriaceae purH GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS04230,iJN678.purH Bacteria 2GJWU@201174,4FKIC@85023,COG0138@1,COG0138@2 NA|NA|NA F AICARFT/IMPCHase bienzyme MAG.T22.42_01361 1120960.ATXG01000010_gene2677 6.5e-203 713.8 Microbacteriaceae pgcA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2,5.4.2.8 ko:K01835,ko:K01840 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114,M00549 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ3Q@201174,4FKU8@85023,COG1109@1,COG1109@2 NA|NA|NA G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II MAG.T22.42_01362 1348338.ADILRU_2454 6.1e-122 443.7 Microbacteriaceae punA GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009120,GO:0009164,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046121,GO:0046122,GO:0046124,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.1 ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 2GKEI@201174,4FK66@85023,COG0005@1,COG0005@2 NA|NA|NA F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate MAG.T22.42_01363 1120960.ATXG01000010_gene2675 4.6e-202 710.7 Microbacteriaceae lpdA GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GMP7@201174,4FKQI@85023,COG1249@1,COG1249@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain MAG.T22.42_01364 298653.Franean1_6614 1e-115 423.7 Frankiales ko:K07133 ko00000 Bacteria 2GK4E@201174,4EUDI@85013,COG1373@1,COG1373@2 NA|NA|NA S AAA domain MAG.T22.42_01365 31964.CMS0630 8.2e-28 130.2 Microbacteriaceae Bacteria 2IIQ5@201174,4FPSA@85023,COG2246@1,COG2246@2 NA|NA|NA S to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides MAG.T22.42_01366 1120960.ATXG01000010_gene2673 2.6e-279 967.6 Microbacteriaceae bccA 6.3.4.14,6.4.1.2,6.4.1.3 ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00741 R00742,R01859,R04385 RC00040,RC00097,RC00253,RC00367,RC00609 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIZP@201174,4FM7Q@85023,COG4770@1,COG4770@2 NA|NA|NA I Biotin carboxylase C-terminal domain MAG.T22.42_01367 1120959.ATXF01000004_gene2936 1e-63 250.0 Microbacteriaceae maf GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944 1.1.1.25,2.1.1.190 ko:K00014,ko:K03215,ko:K06287 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2GNI0@201174,4FN4S@85023,COG0424@1,COG0424@2 NA|NA|NA D Maf-like protein MAG.T22.42_01368 1202962.KB907154_gene641 3.8e-29 136.0 Gammaproteobacteria Bacteria 1R1KJ@1224,1T551@1236,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat MAG.T22.42_01370 1121372.AULK01000002_gene839 5.9e-102 377.9 Microbacteriaceae trmA GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0019843,GO:0030488,GO:0030696,GO:0030697,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 ko00000,ko01000,ko03009,ko03016 Bacteria 2GIR3@201174,4FKQG@85023,COG2265@1,COG2265@2 NA|NA|NA J tRNA (Uracil-5-)-methyltransferase MAG.T22.42_01371 1194165.CAJF01000010_gene795 1.8e-124 452.2 Microbacteriaceae galU GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003983,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006011,GO:0006012,GO:0006073,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009056,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009242,GO:0009244,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016052,GO:0016740,GO:0016772,GO:0016779,GO:0019318,GO:0019320,GO:0019388,GO:0022607,GO:0033499,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046377,GO:0046401,GO:0046483,GO:0046872,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051748,GO:0055086,GO:0065003,GO:0070569,GO:0071704,GO:0071840,GO:1900725,GO:1900727,GO:1901135,GO:1901137,GO:1901360,GO:1901575,GO:1901576,GO:1903509 2.7.7.9,5.4.2.8 ko:K00963,ko:K01840 ko00040,ko00051,ko00052,ko00500,ko00520,ko01100,ko01110,ko01130,map00040,map00051,map00052,map00500,map00520,map01100,map01110,map01130 M00114,M00129,M00361,M00362,M00549 R00289,R01818 RC00002,RC00408 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_1571,iHN637.CLJU_RS02205,iIT341.HP0646 Bacteria 2I2EW@201174,4FKKH@85023,COG1210@1,COG1210@2 NA|NA|NA M Nucleotidyl transferase MAG.T22.42_01373 1120959.ATXF01000004_gene2943 4.5e-278 963.4 Microbacteriaceae pccB GO:0003674,GO:0003824,GO:0003989,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009317,GO:0009987,GO:0015977,GO:0016020,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0030312,GO:0032787,GO:0032991,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:1901575,GO:1902494 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIRU@201174,4FMRC@85023,COG4799@1,COG4799@2 NA|NA|NA I Carboxyl transferase domain MAG.T22.42_01374 281090.Lxx04800 4.3e-59 235.0 Microbacteriaceae birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 2.7.1.33,6.3.4.15 ko:K01947,ko:K03524 ko00770,ko00780,ko01100,map00770,map00780,map01100 M00120 R01074,R02971,R03018,R04391,R05145 RC00002,RC00017,RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 2GN8Q@201174,4FN6Q@85023,COG0340@1,COG0340@2 NA|NA|NA H Biotin protein ligase C terminal domain MAG.T22.42_01375 1001240.GY21_08355 9.3e-29 133.7 Microbacteriaceae Bacteria 2I3WU@201174,4FPB9@85023,COG3402@1,COG3402@2 NA|NA|NA S Bacterial PH domain MAG.T22.42_01376 979556.MTES_0587 3.3e-150 538.1 Microbacteriaceae purK GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477 Bacteria 2GJCU@201174,4FKT4@85023,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) MAG.T22.42_01379 1121934.AUDX01000021_gene1650 1.1e-56 226.1 Microbacteriaceae purE GO:0008150,GO:0040007 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iJN678.purE,iNJ661.Rv3275c Bacteria 2IFFD@201174,4FNKI@85023,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) MAG.T22.42_01380 1001240.GY21_08375 6.2e-119 434.5 Microbacteriaceae Bacteria 2GM55@201174,4FKR4@85023,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-related transcriptional attenuator domain MAG.T22.42_01381 754252.PFREUD_00520 1.3e-37 163.7 Bacteria welB Bacteria COG0463@1,COG0463@2,COG1216@1,COG1216@2 NA|NA|NA M Glycosyl transferase, family 2 MAG.T22.42_01382 1001240.GY21_08415 9.9e-59 234.6 Microbacteriaceae ko:K07011,ko:K20444 ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 2HSIR@201174,4FNT0@85023,COG1216@1,COG1216@2 NA|NA|NA M Glycosyl transferase family 2 MAG.T22.42_01383 1121924.ATWH01000005_gene2785 1.3e-90 339.7 Microbacteriaceae rmlD GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNY8@201174,4FMFC@85023,COG1091@1,COG1091@2 NA|NA|NA M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose MAG.T22.42_01384 1416752.AYME01000003_gene2387 3.1e-168 597.8 Microbacteriaceae rfbB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNDU@201174,4FKJH@85023,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily MAG.T22.42_01385 1416759.AYMR01000001_gene1626 1.5e-80 305.8 Microbacteriaceae rmlC GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008830,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv3465 Bacteria 2GMW4@201174,4FKTI@85023,COG1898@1,COG1898@2 NA|NA|NA M dTDP-4-dehydrorhamnose 3,5-epimerase MAG.T22.42_01386 281090.Lxx04930 2.7e-136 491.5 Microbacteriaceae rfbA GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0334 Bacteria 2GP20@201174,4FKXN@85023,COG1209@1,COG1209@2 NA|NA|NA M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis MAG.T22.42_01387 1121372.AULK01000002_gene857 1.1e-97 363.2 Microbacteriaceae rgpC ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GP5K@201174,4FMEB@85023,COG1682@1,COG1682@2 NA|NA|NA GM ABC-2 type transporter MAG.T22.42_01388 1121372.AULK01000002_gene858 9.6e-95 353.2 Microbacteriaceae 3.6.3.38 ko:K01990,ko:K09689,ko:K09691 ko02010,map02010 M00249,M00250,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.101,3.A.1.103 Bacteria 2GIVF@201174,4FKZ2@85023,COG1134@1,COG1134@2 NA|NA|NA GM ATPases associated with a variety of cellular activities MAG.T22.42_01389 1121924.ATWH01000001_gene4410 6.2e-118 430.3 Microbacteriaceae purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMP4@201174,4FKSZ@85023,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP MAG.T22.42_01390 1120959.ATXF01000005_gene1204 9.6e-142 510.4 Microbacteriaceae ko:K14393 ko00000,ko02000 2.A.21.7 Bacteria 2GM3H@201174,4FTD3@85023,COG4147@1,COG4147@2 NA|NA|NA S Sodium:solute symporter family MAG.T22.42_01391 1120959.ATXF01000005_gene1203 2.3e-11 74.7 Microbacteriaceae Bacteria 2AYZP@1,2HTAZ@201174,31R5Q@2,4FSU6@85023 NA|NA|NA MAG.T22.42_01392 1120959.ATXF01000005_gene1202 1.9e-74 285.8 Microbacteriaceae lytT GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 ko:K02477,ko:K07705 ko02020,map02020 M00492 ko00000,ko00001,ko00002,ko02022 Bacteria 2GKK5@201174,4FQYE@85023,COG3279@1,COG3279@2 NA|NA|NA T LytTr DNA-binding domain MAG.T22.42_01393 1120959.ATXF01000005_gene1201 2.9e-117 428.7 Microbacteriaceae lytS 2.7.13.3,3.1.3.3 ko:K02478,ko:K07315,ko:K07704 ko02020,map02020 M00492 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03021 Bacteria 2GJD4@201174,4FR41@85023,COG3275@1,COG3275@2 NA|NA|NA T Histidine kinase MAG.T22.42_01394 1120960.ATXG01000005_gene2457 2.8e-31 141.4 Microbacteriaceae Bacteria 2IQ5D@201174,4FPW3@85023,COG3162@1,COG3162@2 NA|NA|NA S Protein of unknown function, DUF485 MAG.T22.42_01395 1120959.ATXF01000005_gene1199 4.5e-233 813.9 Microbacteriaceae actP ko:K14393 ko00000,ko02000 2.A.21.7 Bacteria 2GJ56@201174,4FM00@85023,COG4147@1,COG4147@2 NA|NA|NA S Sodium:solute symporter family MAG.T22.42_01396 1449353.JQMQ01000005_gene4094 5.9e-32 143.3 Streptacidiphilus tyrA 5.4.99.5 ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria 2IQ46@201174,2NJ1K@228398,COG1605@1,COG1605@2 NA|NA|NA E Chorismate mutase type II MAG.T22.42_01397 1120960.ATXG01000005_gene2426 0.0 1342.4 Microbacteriaceae purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKG6@201174,4FK8H@85023,COG0046@1,COG0046@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL MAG.T22.42_01398 1121372.AULK01000007_gene423 1.2e-105 390.2 Microbacteriaceae ko:K21405 ko00000,ko03000 Bacteria 2GJV4@201174,4FMCV@85023,COG3284@1,COG3284@2 NA|NA|NA KQ Transcriptional activator of acetoin glycerol metabolism MAG.T22.42_01399 1120959.ATXF01000005_gene1156 6.3e-104 383.6 Microbacteriaceae purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMJY@201174,4FKAC@85023,COG0047@1,COG0047@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL MAG.T22.42_01400 1120960.ATXG01000005_gene2416 4.1e-17 93.6 Microbacteriaceae purS 6.3.2.6,6.3.5.3 ko:K01923,ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463,R04591 RC00010,RC00064,RC00162,RC01160 ko00000,ko00001,ko00002,ko01000 iYO844.BSU06460 Bacteria 2GQV4@201174,4FPZ5@85023,COG1828@1,COG1828@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL MAG.T22.42_01401 1121952.ATXT01000016_gene487 5.1e-156 557.8 Microbacteriaceae Bacteria 2H4H5@201174,4FMIA@85023,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily MAG.T22.42_01402 2045.KR76_18420 1.3e-105 389.8 Propionibacteriales metB 2.5.1.48,4.4.1.8 ko:K01739,ko:K01760 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMD8@201174,4DPBS@85009,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme MAG.T22.42_01403 312284.A20C1_04301 5.9e-38 164.9 unclassified Actinobacteria (class) Bacteria 2GM50@201174,3UWRY@52018,COG0697@1,COG0697@2 NA|NA|NA EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily MAG.T22.42_01404 1132441.KI519454_gene1337 1.5e-151 542.7 Micrococcaceae kynU 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 Bacteria 1WAEG@1268,2GMJQ@201174,COG3844@1,COG3844@2 NA|NA|NA E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively MAG.T22.42_01405 234621.RER_59690 1.7e-48 199.9 Nocardiaceae Bacteria 2HHZM@201174,4G1WR@85025,COG3965@1,COG3965@2 NA|NA|NA P Cation efflux family MAG.T22.42_01406 312284.A20C1_08423 2.1e-115 422.2 unclassified Actinobacteria (class) purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 ko:K01923,ko:K01945,ko:K03566 ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 2GK3H@201174,3UWES@52018,COG0152@1,COG0152@2 NA|NA|NA F SAICAR synthetase MAG.T22.42_01407 273677.BW34_01553 5.5e-162 577.4 Microbacteriaceae purD GO:0000166,GO:0003674,GO:0003824,GO:0004637,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.3.1,6.3.4.13,6.3.5.3 ko:K01945,ko:K01952,ko:K11788,ko:K13713 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208,R04463,R04591 RC00010,RC00064,RC00090,RC00162,RC00166,RC01100,RC01160 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_3417,iECSF_1327.ECSF_3859,iJN746.PP_4823,iPC815.YPO3729,iSB619.SA_RS05245,iYO844.BSU06530 Bacteria 2I2F5@201174,4FKYA@85023,COG0151@1,COG0151@2 NA|NA|NA F Phosphoribosylglycinamide synthetase, C domain MAG.T22.42_01408 1033736.CAHK01000015_gene816 6.3e-08 63.5 Brevibacteriaceae Bacteria 2ER8U@1,2HXY5@201174,33IUE@2,4FAHQ@85019 NA|NA|NA MAG.T22.42_01409 1499502.EV12_2418 1.4e-230 805.4 Cyanobacteria purF GO:0003674,GO:0003824,GO:0004044,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0034654,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 iAF1260.b2312,iB21_1397.B21_02197,iBWG_1329.BWG_2086,iECBD_1354.ECBD_1347,iECB_1328.ECB_02237,iECDH10B_1368.ECDH10B_2474,iECDH1ME8569_1439.ECDH1ME8569_2250,iECD_1391.ECD_02237,iECIAI1_1343.ECIAI1_2389,iECO103_1326.ECO103_2776,iECO111_1330.ECO111_3060,iECO26_1355.ECO26_3300,iECW_1372.ECW_m2501,iEKO11_1354.EKO11_1453,iETEC_1333.ETEC_2448,iEcDH1_1363.EcDH1_1344,iEcE24377_1341.EcE24377A_2606,iEcolC_1368.EcolC_1340,iJO1366.b2312,iJR904.b2312,iSF_1195.SF2388,iSFxv_1172.SFxv_2633,iSSON_1240.SSON_2370,iS_1188.S2523,iSbBS512_1146.SbBS512_E2690,iUMNK88_1353.UMNK88_2863,iWFL_1372.ECW_m2501,iY75_1357.Y75_RS12125 Bacteria 1GBV1@1117,1MKNP@1212,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine MAG.T22.42_01410 1120960.ATXG01000005_gene2380 1.3e-156 559.3 Microbacteriaceae purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1844,iECSF_1327.ECSF_2340 Bacteria 2GJNY@201174,4FKR7@85023,COG0150@1,COG0150@2 NA|NA|NA F AIR synthase related protein, C-terminal domain MAG.T22.42_01411 1120959.ATXF01000005_gene1119 8.7e-12 75.9 Microbacteriaceae Bacteria 2EGRW@1,2GSKD@201174,33AI2@2,4FQH0@85023 NA|NA|NA S Protein of unknown function (DUF3073) MAG.T22.42_01412 1120960.ATXG01000005_gene2372 1.2e-19 102.8 Microbacteriaceae crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 2HYGW@201174,4FQE2@85023,COG0239@1,COG0239@2 NA|NA|NA D CrcB-like protein, Camphor Resistance (CrcB) MAG.T22.42_01413 1120959.ATXF01000005_gene1110 9.9e-15 86.7 Bacteria crcB2 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria COG0239@1,COG0239@2 NA|NA|NA D Important for reducing fluoride concentration in the cell, thus reducing its toxicity MAG.T22.42_01414 1120960.ATXG01000005_gene2367 1.1e-66 260.0 Microbacteriaceae tipA ko:K21744 ko00000,ko03000 Bacteria 2H5GI@201174,4FMH1@85023,COG0789@1,COG0789@2 NA|NA|NA K TipAS antibiotic-recognition domain MAG.T22.42_01415 1121924.ATWH01000001_gene4353 1.4e-66 259.6 Microbacteriaceae ko:K07149 ko00000 Bacteria 2GKA1@201174,4FNSN@85023,COG2364@1,COG2364@2 NA|NA|NA S membrane MAG.T22.42_01416 529884.Rhola_00013380 1.6e-100 372.5 Microbacteriaceae gip 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 R01394 RC00511 ko00000,ko00001,ko01000 Bacteria 2GKPC@201174,4FQ0R@85023,COG3622@1,COG3622@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T22.42_01417 1194165.CAJF01000009_gene892 2.5e-144 518.5 Microbacteriaceae tal 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMF9@201174,4FRMB@85023,COG0176@1,COG0176@2 NA|NA|NA G Pfam:Transaldolase MAG.T22.42_01418 31964.CMS2385 4.8e-97 360.9 Microbacteriaceae yegW ko:K03710 ko00000,ko03000 Bacteria 2GJZ1@201174,4FM55@85023,COG2188@1,COG2188@2 NA|NA|NA K UTRA MAG.T22.42_01419 1120960.ATXG01000005_gene2454 6e-62 244.6 Microbacteriaceae Bacteria 2GK49@201174,4FKTG@85023,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family MAG.T22.42_01420 1122237.AUGQ01000013_gene590 1.7e-105 389.0 Microbacteriaceae iolTC 3.6.3.17 ko:K02056 M00221 ko00000,ko00002,ko01000,ko02000 3.A.1.2 Bacteria 2GJDV@201174,4FKQP@85023,COG1129@1,COG1129@2 NA|NA|NA G ABC transporter, ATP-binding protein MAG.T22.42_01421 1122237.AUGQ01000013_gene591 2.7e-135 488.4 Microbacteriaceae iolTB ko:K02057,ko:K03466 M00221 ko00000,ko00002,ko02000,ko03036 3.A.1.2,3.A.12 Bacteria 2GM9E@201174,4FK9K@85023,COG1172@1,COG1172@2 NA|NA|NA G Belongs to the binding-protein-dependent transport system permease family MAG.T22.42_01422 1122237.AUGQ01000013_gene592 4.7e-97 361.3 Microbacteriaceae iolTA ko:K02058,ko:K10439 ko02010,ko02030,map02010,map02030 M00212,M00221 ko00000,ko00001,ko00002,ko02000 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria 2GKIJ@201174,4FKSC@85023,COG1879@1,COG1879@2 NA|NA|NA G sugar ABC transporter, substrate-binding protein MAG.T22.42_01423 1121934.AUDX01000003_gene860 9.8e-42 177.6 Microbacteriaceae ko:K02529 ko00000,ko03000 Bacteria 2GK1X@201174,4FNP3@85023,COG1609@1,COG1609@2 NA|NA|NA K Bacterial regulatory proteins, lacI family MAG.T22.42_01424 529884.Rhola_00013420 1.2e-153 549.7 Microbacteriaceae Bacteria 2GK0F@201174,4FM1R@85023,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain MAG.T22.42_01425 1184607.AUCHE_08_02400 2.2e-93 349.0 Dermatophilaceae 4.2.1.44 ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 R02782,R05659 RC00782,RC01448 ko00000,ko00001,ko01000 Bacteria 2GJKJ@201174,4F75X@85018,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel MAG.T22.42_01426 1120960.ATXG01000008_gene267 5.2e-101 374.4 Microbacteriaceae glkA GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJCQ@201174,4FKEG@85023,COG1940@1,COG1940@2 NA|NA|NA GK ROK family MAG.T22.42_01427 529884.Rhola_00013400 1.7e-121 442.6 Microbacteriaceae 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 R01183,R09951 RC00182 ko00000,ko00001,ko01000 Bacteria 2GJCY@201174,4FM2G@85023,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain MAG.T22.42_01428 529884.Rhola_00013390 6.4e-99 367.5 Bacteria 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 Bacteria COG1091@1,COG1091@2 NA|NA|NA M dTDP-4-dehydrorhamnose reductase activity MAG.T22.42_01429 1120960.ATXG01000003_gene1829 4.2e-66 257.7 Microbacteriaceae fcbC ko:K07107,ko:K12500 ko00000,ko01000,ko01004 Bacteria 2IHBJ@201174,4FNDN@85023,COG0824@1,COG0824@2 NA|NA|NA S Thioesterase-like superfamily MAG.T22.42_01430 1120959.ATXF01000006_gene1965 1.3e-159 569.3 Microbacteriaceae prpC 2.3.3.1,2.3.3.5 ko:K01647,ko:K01659 ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351,R00931 RC00004,RC00067,RC00406,RC02827 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ7E@201174,4FKJE@85023,COG0372@1,COG0372@2 NA|NA|NA C Citrate synthase, C-terminal domain MAG.T22.42_01431 1120960.ATXG01000003_gene1832 3.3e-137 494.6 Microbacteriaceae prpB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046421,GO:0046459,GO:0046872,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.1.3.30 ko:K03417 ko00640,map00640 R00409 RC00286,RC00287 ko00000,ko00001,ko01000 iECNA114_1301.ECNA114_0319,iECP_1309.ECP_0407 Bacteria 2GJZZ@201174,4FKFW@85023,COG2513@1,COG2513@2 NA|NA|NA G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate MAG.T22.42_01432 1121924.ATWH01000014_gene3442 2.4e-241 841.3 Microbacteriaceae prpD GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 ko:K01720 ko00640,map00640 R04424 RC01152 ko00000,ko00001,ko01000 Bacteria 2GKUR@201174,4FMAS@85023,COG2079@1,COG2079@2 NA|NA|NA S MmgE/PrpD family MAG.T22.42_01433 1278308.KB907081_gene2527 5.2e-55 221.1 Microbacteriaceae Bacteria 2II9S@201174,4FNQQ@85023,COG1802@1,COG1802@2 NA|NA|NA K FCD MAG.T22.42_01434 685727.REQ_10070 5.1e-249 867.1 Nocardiaceae prpE 6.2.1.1,6.2.1.17 ko:K01895,ko:K01908 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GP7N@201174,4FV0U@85025,COG0365@1,COG0365@2 NA|NA|NA I Acetyl-coenzyme A synthetase N-terminus MAG.T22.42_01435 134676.ACPL_4513 0.0 1192.9 Micromonosporales MA20_17010 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GND8@201174,4DC0M@85008,COG2609@1,COG2609@2 NA|NA|NA C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) MAG.T22.42_01436 1452535.JARD01000006_gene3119 3.7e-157 561.2 Microbacteriaceae 2.5.1.48,4.4.1.11,4.4.1.8 ko:K01739,ko:K01760,ko:K01761 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ5S@201174,4FMTB@85023,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme MAG.T22.42_01437 408672.NBCG_03844 7.5e-40 170.2 Propionibacteriales Bacteria 2HQED@201174,4DV5G@85009,COG1522@1,COG1522@2 NA|NA|NA K helix_turn_helix ASNC type MAG.T22.42_01438 196627.cg0202 3.1e-286 990.7 Corynebacteriaceae iolD GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046434,GO:0071704,GO:1901575 3.7.1.22 ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 R08603 RC02331 ko00000,ko00001,ko01000 iYO844.BSU39730 Bacteria 22Q69@1653,2GMCJ@201174,COG3962@1,COG3962@2 NA|NA|NA C Thiamine pyrophosphate enzyme, central domain MAG.T22.42_01439 273677.BW34_01526 8.1e-110 403.7 Microbacteriaceae iolB 5.3.1.30 ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 R08503 RC00541 ko00000,ko00001,ko01000 Bacteria 2GM8S@201174,4FMR9@85023,COG3718@1,COG3718@2 NA|NA|NA G KduI/IolB family MAG.T22.42_01440 1120958.AULD01000005_gene2229 5.7e-227 793.5 Microbacteriaceae mmsA 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJI2@201174,4FKHY@85023,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family MAG.T22.42_01441 649754.HMPREF0281_02531 1.2e-107 396.4 Corynebacteriaceae Bacteria 22Q2I@1653,2GKTN@201174,COG1830@1,COG1830@2 NA|NA|NA G deoxyribose-phosphate aldolase MAG.T22.42_01442 443906.CMM_0774 4e-130 471.1 Microbacteriaceae iolC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044262,GO:0044424,GO:0044464,GO:0046434,GO:0046835,GO:0071704,GO:1901575 2.7.1.92 ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 R05661 RC00002,RC00017 ko00000,ko00001,ko01000 iYO844.BSU39740 Bacteria 2GM3N@201174,4FM32@85023,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase MAG.T22.42_01443 1120959.ATXF01000006_gene1633 3.5e-188 664.5 Microbacteriaceae aspC Bacteria 2GJ7R@201174,4FM0Z@85023,COG0436@1,COG0436@2 NA|NA|NA E DegT/DnrJ/EryC1/StrS aminotransferase family MAG.T22.42_01444 1001240.GY21_19800 7.3e-39 166.8 Actinobacteria Bacteria 2IJK0@201174,COG1598@1,COG1598@2 NA|NA|NA S PFAM Uncharacterised protein family UPF0150 MAG.T22.42_01445 479432.Sros_2599 8.9e-27 126.7 Actinobacteria Bacteria 2BVIR@1,2IIDS@201174,32QWU@2 NA|NA|NA MAG.T22.42_01447 1120959.ATXF01000006_gene1629 6.5e-112 410.6 Microbacteriaceae nusG GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 2GJFW@201174,4FK7R@85023,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination MAG.T22.42_01448 76636.JOEC01000002_gene1945 2.3e-65 255.0 Microbacteriaceae rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFCK@201174,4FNGC@85023,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors MAG.T22.42_01449 1150399.AQYK01000001_gene800 2.5e-108 398.3 Microbacteriaceae rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GM51@201174,4FKT2@85023,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release MAG.T22.42_01450 1120960.ATXG01000001_gene1042 2.3e-220 771.5 Microbacteriaceae Bacteria 2GIWQ@201174,4FMY7@85023,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease MAG.T22.42_01451 1120960.ATXG01000001_gene1049 9.9e-126 456.8 Microbacteriaceae Bacteria 2GIU7@201174,4FM14@85023,COG1804@1,COG1804@2 NA|NA|NA C CoA-transferase family III MAG.T22.42_01452 1120959.ATXF01000006_gene1618 3.6e-152 544.7 Microbacteriaceae gcdH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIX8@201174,4FK4G@85023,COG1960@1,COG1960@2 NA|NA|NA I Acyl-CoA dehydrogenase, middle domain MAG.T22.42_01453 1151122.AQYD01000007_gene540 2.1e-15 88.6 Microbacteriaceae Bacteria 2GVQB@201174,4FQMF@85023,COG5646@1,COG5646@2 NA|NA|NA S Domain of unknown function (DU1801) MAG.T22.42_01454 1416759.AYMR01000024_gene2559 6.9e-171 607.1 Microbacteriaceae ssdA 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWZ@201174,4FMPX@85023,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family MAG.T22.42_01456 1121926.AXWO01000001_gene3644 1.4e-26 126.3 Actinobacteria Bacteria 2DMWY@1,2ISFN@201174,32U6G@2 NA|NA|NA MAG.T22.42_01457 1449058.JQKT01000007_gene532 6.7e-217 760.0 Microbacteriaceae ko:K07110 ko00000,ko03000 Bacteria 2GMWU@201174,4FKRS@85023,COG1476@1,COG1476@2,COG3800@1,COG3800@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins MAG.T22.42_01458 1120959.ATXF01000006_gene1591 4.6e-212 743.8 Microbacteriaceae aceA GO:0001101,GO:0001666,GO:0003674,GO:0003824,GO:0004451,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0006950,GO:0008150,GO:0008152,GO:0009268,GO:0009405,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0010033,GO:0010034,GO:0010447,GO:0016020,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019899,GO:0032787,GO:0033554,GO:0033993,GO:0035375,GO:0036293,GO:0036294,GO:0042221,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046421,GO:0046487,GO:0046677,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0070542,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071944,GO:0072350,GO:0075136,GO:0075141,GO:1901700 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 e_coli_core.b4015,iAF1260.b4015,iB21_1397.B21_03847,iBWG_1329.BWG_3671,iE2348C_1286.E2348C_4318,iEC042_1314.EC042_4377,iEC55989_1330.EC55989_4500,iECABU_c1320.ECABU_c45310,iECBD_1354.ECBD_4022,iECB_1328.ECB_03887,iECDH10B_1368.ECDH10B_4204,iECDH1ME8569_1439.ECDH1ME8569_3871,iECD_1391.ECD_03887,iECED1_1282.ECED1_4722,iECIAI1_1343.ECIAI1_4235,iECIAI39_1322.ECIAI39_4401,iECNA114_1301.ECNA114_4164,iECO103_1326.ECO103_4759,iECO111_1330.ECO111_4827,iECO26_1355.ECO26_5119,iECP_1309.ECP_4225,iECSE_1348.ECSE_4300,iECSF_1327.ECSF_3865,iECUMN_1333.ECUMN_4541,iECW_1372.ECW_m4374,iEKO11_1354.EKO11_4310,iETEC_1333.ETEC_4270,iEcDH1_1363.EcDH1_3982,iEcE24377_1341.EcE24377A_4557,iEcHS_1320.EcHS_A4249,iEcSMS35_1347.EcSMS35_4469,iEcolC_1368.EcolC_4015,iJN746.PP_4116,iJO1366.b4015,iJR904.b4015,iLF82_1304.LF82_0012,iNRG857_1313.NRG857_20015,iSDY_1059.SDY_4328,iUMNK88_1353.UMNK88_4859,iWFL_1372.ECW_m4374,iY75_1357.Y75_RS20880 Bacteria 2GNAY@201174,4FM85@85023,COG2224@1,COG2224@2 NA|NA|NA C Isocitrate lyase family MAG.T22.42_01459 1120960.ATXG01000001_gene1087 4.5e-225 787.3 Microbacteriaceae aceB GO:0003674,GO:0003824,GO:0004474,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044464,GO:0046487,GO:0046912,GO:0071704 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 iEC55989_1330.EC55989_4499,iLF82_1304.LF82_0013,iNRG857_1313.NRG857_20010 Bacteria 2GJGP@201174,4FK7E@85023,COG2225@1,COG2225@2 NA|NA|NA C Malate synthase MAG.T22.42_01460 1451261.AS96_09845 1.8e-163 582.4 Microbacteriaceae phr GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 ko:K01669 ko00000,ko01000,ko03400 Bacteria 2GJXU@201174,4FM8K@85023,COG0415@1,COG0415@2 NA|NA|NA L DNA photolyase MAG.T22.42_01461 1120960.ATXG01000001_gene1094 6.6e-65 253.8 Microbacteriaceae Bacteria 2C95E@1,2IGH0@201174,33XTJ@2,4FNE4@85023 NA|NA|NA S YqaJ-like viral recombinase domain MAG.T22.42_01462 1120960.ATXG01000001_gene1103 9.7e-52 210.3 Microbacteriaceae Bacteria 2A6W4@1,2GIS5@201174,30VQS@2,4FNXH@85023 NA|NA|NA S Putative amidase domain MAG.T22.42_01463 1416759.AYMR01000013_gene2440 2.7e-86 325.1 Microbacteriaceae ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GK3I@201174,4FMNI@85023,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities MAG.T22.42_01464 979556.MTES_1460 9.4e-119 434.1 Microbacteriaceae ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GMH5@201174,4FN5W@85023,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family MAG.T22.42_01465 1120959.ATXF01000009_gene856 1.4e-109 402.5 Microbacteriaceae Bacteria 2GIZB@201174,4FKPR@85023,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal MAG.T22.42_01466 1120960.ATXG01000001_gene1107 3e-116 425.6 Microbacteriaceae Bacteria 2GIV9@201174,4FKMW@85023,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor MAG.T22.42_01468 1043493.BBLU01000015_gene1168 1.9e-174 619.0 Actinobacteria 1.8.5.4 ko:K17218 ko00920,map00920 R10152 RC03155 ko00000,ko00001,ko01000 Bacteria 2IB5R@201174,COG0446@1,COG0446@2 NA|NA|NA S Pyridine nucleotide-disulphide oxidoreductase MAG.T22.42_01469 1121372.AULK01000006_gene1518 4.6e-75 287.3 Microbacteriaceae rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GM0V@201174,4FKC5@85023,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors MAG.T22.42_01470 1122239.AULS01000008_gene2359 2.3e-42 178.3 Microbacteriaceae rplL GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKNW@201174,4FP4B@85023,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation MAG.T22.42_01471 1120959.ATXF01000009_gene835 5.3e-117 427.9 Microbacteriaceae yjeH GO:0000099,GO:0000101,GO:0000102,GO:0001101,GO:0003333,GO:0003674,GO:0005215,GO:0005294,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015191,GO:0015238,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015821,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043200,GO:0043865,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:1901680,GO:1901682,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 ko:K03294,ko:K16263 ko00000,ko02000 2.A.3.13,2.A.3.2 Bacteria 2IAK1@201174,4FKTR@85023,COG0531@1,COG0531@2 NA|NA|NA E Spore germination protein MAG.T22.42_01472 494419.ALPM01000017_gene634 9.4e-98 364.0 Micrococcaceae nhaA ko:K03313 ko00000,ko02000 2.A.33.1 Bacteria 1W7J0@1268,2GKIK@201174,COG3004@1,COG3004@2 NA|NA|NA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons MAG.T22.42_01473 1120959.ATXF01000009_gene824 2e-30 137.9 Microbacteriaceae nrdH ko:K06191 ko00000 Bacteria 2IRCP@201174,4FPHW@85023,COG0695@1,COG0695@2 NA|NA|NA O Glutaredoxin MAG.T22.42_01474 1120959.ATXF01000009_gene823 1.1e-55 222.6 Microbacteriaceae nrdI ko:K03647 ko00000 Bacteria 2IM4D@201174,4FNS2@85023,COG1780@1,COG1780@2 NA|NA|NA F Probably involved in ribonucleotide reductase function MAG.T22.42_01476 1416752.AYME01000013_gene3114 6.2e-185 653.7 Microbacteriaceae tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2GJPR@201174,4FKCN@85023,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) MAG.T22.42_01477 529884.Rhola_00005410 5.6e-09 68.9 Bacteria ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 Bacteria COG2268@1,COG2268@2 NA|NA|NA T Band 7 protein MAG.T22.42_01478 529884.Rhola_00005410 3.2e-09 69.7 Bacteria ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 Bacteria COG2268@1,COG2268@2 NA|NA|NA T Band 7 protein MAG.T22.42_01479 1120960.ATXG01000026_gene3356 2.7e-194 684.9 Microbacteriaceae argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.argH Bacteria 2GJ2A@201174,4FKM4@85023,COG0165@1,COG0165@2 NA|NA|NA E arginine biosynthetic process via ornithine MAG.T22.42_01480 1416759.AYMR01000001_gene1505 7.9e-134 483.4 Microbacteriaceae argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ6H@201174,4FK5M@85023,COG0078@1,COG0078@2 NA|NA|NA E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline MAG.T22.42_01481 1120959.ATXF01000012_gene3165 4.7e-131 474.2 Microbacteriaceae argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS10565,iJN678.argB,iLJ478.TM1784 Bacteria 2GKDS@201174,4FK9H@85023,COG0548@1,COG0548@2 NA|NA|NA E Belongs to the acetylglutamate kinase family. ArgB subfamily MAG.T22.42_01482 1120959.ATXF01000012_gene3166 2.3e-167 595.1 Microbacteriaceae argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 ko:K00620,ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIW0@201174,4FKP1@85023,COG1364@1,COG1364@2 NA|NA|NA E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate MAG.T22.42_01483 1001240.GY21_06330 5e-137 494.2 Microbacteriaceae argC GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKQK@201174,4FKC3@85023,COG0002@1,COG0002@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde MAG.T22.42_01484 1150398.JIBJ01000007_gene201 6.5e-30 137.1 Micrococcaceae Bacteria 1W9WR@1268,2CHCP@1,2IRB0@201174,32S5R@2 NA|NA|NA S Domain of unknown function (DU1801) MAG.T22.42_01485 1120959.ATXF01000012_gene3168 5.2e-310 1070.1 Microbacteriaceae pheT GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GMFD@201174,4FK5R@85023,COG0072@1,COG0072@2,COG0073@1,COG0073@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily MAG.T22.42_01486 273677.BW34_02823 1.5e-149 535.8 Microbacteriaceae pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJGG@201174,4FKSV@85023,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily MAG.T22.42_01487 1416759.AYMR01000001_gene1516 3.3e-112 411.4 Microbacteriaceae tsnR 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 2GJI6@201174,4FKF8@85023,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family MAG.T22.42_01488 1120959.ATXF01000012_gene3175 2.5e-54 218.0 Microbacteriaceae rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHTN@201174,4FNQN@85023,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit MAG.T22.42_01489 1120958.AULD01000007_gene1230 9.2e-21 105.5 Microbacteriaceae rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02916 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQZW@201174,4FPZF@85023,COG0291@1,COG0291@2 NA|NA|NA J structural constituent of ribosome MAG.T22.42_01490 1389489.O159_21790 4.2e-84 317.8 Microbacteriaceae infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 2GJGT@201174,4FMC5@85023,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins MAG.T22.42_01491 1122175.ATXU01000004_gene2214 1e-32 145.6 Microbacteriaceae Bacteria 2AI3Y@1,2IHSQ@201174,318HW@2,4FP40@85023 NA|NA|NA MAG.T22.42_01492 1451261.AS96_06620 1.4e-62 246.5 Microbacteriaceae ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 2GMN0@201174,4FTMB@85023,COG1404@1,COG1404@2 NA|NA|NA O SseB protein N-terminal domain MAG.T22.42_01493 1151126.AQYI01000005_gene2694 2.4e-98 365.2 Microbacteriaceae hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16,5.3.1.24 ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 M00023,M00026 R03509,R04640 RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ4V@201174,4FMEY@85023,COG0106@1,COG0106@2 NA|NA|NA E Histidine biosynthesis protein MAG.T22.42_01494 1150399.AQYK01000002_gene2470 7e-89 333.6 Microbacteriaceae hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIYS@201174,4FKZP@85023,COG0118@1,COG0118@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR MAG.T22.42_01495 1121924.ATWH01000015_gene3608 3.4e-90 337.8 Microbacteriaceae hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19 ko:K00013,ko:K00817,ko:K01089,ko:K01693 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R01158,R01163,R03012,R03013,R03243,R03457 RC00006,RC00017,RC00099,RC00242,RC00463,RC00888,RC00932 ko00000,ko00001,ko00002,ko01000,ko01007 iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iLJ478.TM1039,iSB619.SA_RS14130,iUMNK88_1353.UMNK88_2570 Bacteria 2GKMD@201174,4FMRW@85023,COG0131@1,COG0131@2 NA|NA|NA E imidazoleglycerol-phosphate dehydratase activity MAG.T22.42_01496 1416759.AYMR01000017_gene2371 8.3e-151 540.0 Microbacteriaceae hisC GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GJ9W@201174,4FKMU@85023,COG0079@1,COG0079@2 NA|NA|NA E Aminotransferase class I and II MAG.T22.42_01497 1150399.AQYK01000002_gene2473 2.1e-20 105.1 Microbacteriaceae Bacteria 2GWI9@201174,4FQ73@85023,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif MAG.T22.42_01498 443906.CMM_2018 1.2e-94 352.8 Microbacteriaceae lexA 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 2GMBN@201174,4FKD4@85023,COG1974@1,COG1974@2 NA|NA|NA K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair MAG.T22.42_01499 1120960.ATXG01000009_gene17 3.3e-105 388.3 Microbacteriaceae metF GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJTN@201174,4FMP8@85023,COG0685@1,COG0685@2 NA|NA|NA E Methylenetetrahydrofolate reductase MAG.T22.42_01500 1150399.AQYK01000002_gene2478 1.1e-201 709.5 Microbacteriaceae hflX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 ko:K03665 ko00000,ko03009 Bacteria 2GK55@201174,4FMCI@85023,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis MAG.T22.42_01501 926564.KI911665_gene707 2.7e-69 268.5 Promicromonosporaceae rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 2IFG7@201174,4F43C@85017,COG2813@1,COG2813@2 NA|NA|NA J Putative methyltransferase MAG.T22.42_01502 1121934.AUDX01000004_gene2598 3.1e-27 128.3 Actinobacteria Bacteria 2E3RQ@1,2I876@201174,32SHZ@2 NA|NA|NA MAG.T22.42_01503 1001240.GY21_06495 4.7e-120 437.6 Microbacteriaceae dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 iIT341.HP0566,iLJ478.TM1522 Bacteria 2GKUD@201174,4FKHM@85023,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan MAG.T22.42_01504 1120960.ATXG01000009_gene21 6.2e-93 347.4 Microbacteriaceae miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 2GKFT@201174,4FKAI@85023,COG0324@1,COG0324@2 NA|NA|NA J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) MAG.T22.42_01505 1120959.ATXF01000012_gene3196 1.6e-237 828.6 Microbacteriaceae miaB 2.8.4.3 ko:K06168 R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 Bacteria 2GJEV@201174,4FK4K@85023,COG0621@1,COG0621@2 NA|NA|NA J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine MAG.T22.42_01506 1122609.AUGT01000003_gene2434 6.8e-146 524.6 Propionibacteriales ko:K06994 ko00000 Bacteria 2GIRQ@201174,4DPRE@85009,COG2409@1,COG2409@2 NA|NA|NA S MMPL family MAG.T22.42_01507 1123251.ATWM01000009_gene2917 5.1e-29 134.4 Intrasporangiaceae Bacteria 2GUZX@201174,4FH71@85021,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein MAG.T22.42_01508 1121934.AUDX01000014_gene1559 2.5e-20 105.9 Microbacteriaceae recX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03565 ko00000,ko03400 Bacteria 2I0B1@201174,4FQ9U@85023,COG2137@1,COG2137@2 NA|NA|NA S Modulates RecA activity MAG.T22.42_01509 1120959.ATXF01000012_gene3198 1.8e-174 618.6 Microbacteriaceae recA GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043142,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 2GJ4P@201174,4FM3R@85023,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage MAG.T22.42_01510 979556.MTES_0306 7.1e-12 76.3 Microbacteriaceae Bacteria 2EFU9@1,2GQJW@201174,339KE@2,4FQ35@85023 NA|NA|NA S Protein of unknown function (DUF3046) MAG.T22.42_01511 443906.CMM_2027 2.9e-37 161.0 Microbacteriaceae clgR GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006109,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009268,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009987,GO:0010447,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0010675,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031347,GO:0031348,GO:0032268,GO:0032502,GO:0033554,GO:0035821,GO:0040007,GO:0042176,GO:0043207,GO:0043565,GO:0043620,GO:0044003,GO:0044110,GO:0044111,GO:0044114,GO:0044115,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060255,GO:0061136,GO:0062012,GO:0065007,GO:0075136,GO:0080090,GO:0080134,GO:0085016,GO:0090062,GO:0097159,GO:1901363,GO:1902680,GO:1902882,GO:1903050,GO:1903362,GO:1903506,GO:1903508,GO:2000112,GO:2001141 ko:K07075 ko00000 Bacteria 2GR3F@201174,4FP2T@85023,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins MAG.T22.42_01512 1449058.JQKT01000007_gene1814 5.4e-33 147.5 Microbacteriaceae cinA 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 2IQ8T@201174,4FPN9@85023,COG1546@1,COG1546@2 NA|NA|NA S Competence-damaged protein MAG.T22.42_01513 1120959.ATXF01000012_gene3207 1.4e-61 242.7 Microbacteriaceae pgsA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 Bacteria 2GK5D@201174,4FK75@85023,COG0558@1,COG0558@2 NA|NA|NA I CDP-alcohol phosphatidyltransferase MAG.T22.42_01514 1121924.ATWH01000015_gene3590 1.4e-146 526.2 Microbacteriaceae ftsK GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03466 ko00000,ko03036 3.A.12 Bacteria 2GK3T@201174,4FKFU@85023,COG1674@1,COG1674@2 NA|NA|NA D Ftsk_gamma MAG.T22.42_01515 1120959.ATXF01000010_gene47 1.8e-22 112.5 Microbacteriaceae Bacteria 2E9Y4@1,2GR3H@201174,3343S@2,4FPQX@85023 NA|NA|NA MAG.T22.42_01516 593907.Celgi_2319 2.2e-19 101.7 Cellulomonadaceae Bacteria 2CXFQ@1,2GQYH@201174,32T1V@2,4F1HG@85016 NA|NA|NA S TadE-like protein MAG.T22.42_01517 1120959.ATXF01000010_gene49 1.7e-13 81.3 Microbacteriaceae Bacteria 2EG89@1,2GX3U@201174,33A03@2,4FQQM@85023 NA|NA|NA MAG.T22.42_01518 1120959.ATXF01000010_gene50 9.5e-44 184.1 Microbacteriaceae ko:K12511 ko00000,ko02044 Bacteria 2GK7B@201174,4FM4R@85023,COG2064@1,COG2064@2 NA|NA|NA NU Type II secretion system (T2SS), protein F MAG.T22.42_01519 1120960.ATXG01000002_gene2725 2.4e-52 212.6 Microbacteriaceae tadC2 ko:K12510,ko:K12511 ko00000,ko02044 Bacteria 2GKMW@201174,4FMXU@85023,COG2064@1,COG2064@2 NA|NA|NA NU Type II secretion system (T2SS), protein F MAG.T22.42_01520 1120959.ATXF01000010_gene52 3.9e-119 434.9 Microbacteriaceae msi031 ko:K02283 ko00000,ko02035,ko02044 Bacteria 2GKKJ@201174,4FKCP@85023,COG4962@1,COG4962@2 NA|NA|NA U Type II/IV secretion system protein MAG.T22.42_01522 1122238.AULR01000019_gene1172 9.1e-130 469.9 Microbacteriaceae cysK GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIXE@201174,4FKBA@85023,COG0031@1,COG0031@2 NA|NA|NA E Pyridoxal-phosphate dependent enzyme MAG.T22.42_01523 1121924.ATWH01000011_gene351 2.9e-72 278.5 Microbacteriaceae ko:K03975 ko00000 Bacteria 2GKGR@201174,4FNU2@85023,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein MAG.T22.42_01524 1120959.ATXF01000010_gene57 1.2e-64 253.1 Microbacteriaceae hmuO GO:0003674,GO:0003824,GO:0004392,GO:0005488,GO:0005575,GO:0006725,GO:0006778,GO:0006787,GO:0006788,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016020,GO:0016491,GO:0016705,GO:0019439,GO:0020037,GO:0033013,GO:0033015,GO:0034641,GO:0042167,GO:0042168,GO:0042440,GO:0042592,GO:0044237,GO:0044248,GO:0044270,GO:0046149,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051187,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:0098771,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575 1.14.15.20 ko:K21480 ko00860,ko01100,ko01110,map00860,map01100,map01110 R11579 RC01270 ko00000,ko00001,ko01000 Bacteria 2H90I@201174,4FNDA@85023,COG5398@1,COG5398@2 NA|NA|NA P Heme oxygenase MAG.T22.42_01525 1120959.ATXF01000010_gene58 4.4e-82 311.2 Microbacteriaceae dedA ko:K03975 ko00000 Bacteria 2GKGR@201174,4FR3Y@85023,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein MAG.T22.42_01526 1177594.MIC448_300005 4.6e-88 331.3 Microbacteriaceae sseA 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 Bacteria 2GMDR@201174,4FMSZ@85023,COG2897@1,COG2897@2 NA|NA|NA P Rhodanese Homology Domain MAG.T22.42_01527 1120959.ATXF01000010_gene60 1.5e-56 226.1 Microbacteriaceae rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 2GM2B@201174,4FNI5@85023,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions MAG.T22.42_01528 1120959.ATXF01000010_gene61 1.4e-109 402.5 Microbacteriaceae rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56,3.6.1.66 ko:K00989,ko:K02428 ko00230,map00230 R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03016 Bacteria 2GJFI@201174,4FM9E@85023,COG0689@1,COG0689@2 NA|NA|NA J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates MAG.T22.42_01529 1120959.ATXF01000010_gene62 1.5e-123 449.1 Microbacteriaceae murI GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0042802,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 iYO844.BSU28390 Bacteria 2GN4I@201174,4FMGX@85023,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis MAG.T22.42_01530 1120959.ATXF01000010_gene64 4.2e-35 153.7 Microbacteriaceae Bacteria 2CAFG@1,2IQ98@201174,32RRB@2,4FPI5@85023 NA|NA|NA S Protein of unknown function (DUF3039) MAG.T22.42_01531 1150399.AQYK01000001_gene1542 4.4e-78 297.7 Microbacteriaceae phnW 2.6.1.37,2.7.7.74,2.7.8.12 ko:K03430,ko:K07281,ko:K09809 ko00440,ko00562,ko01100,ko01120,map00440,map00562,map01100,map01120 R04152,R09669 RC00002,RC00008,RC00062 ko00000,ko00001,ko01000,ko01007 Bacteria 2GN1Y@201174,4FMGB@85023,COG1213@1,COG1213@2 NA|NA|NA M MobA-like NTP transferase domain MAG.T22.42_01532 1120960.ATXG01000007_gene457 2e-93 349.0 Microbacteriaceae rfbA ko:K01992,ko:K09690 ko02010,map02010 M00250,M00254 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.103 Bacteria 2GP5K@201174,4FMSK@85023,COG1682@1,COG1682@2 NA|NA|NA GM ABC-2 type transporter MAG.T22.42_01533 76636.JOEC01000002_gene2722 6.8e-104 383.6 Microbacteriaceae rfbB 3.6.3.38 ko:K01990,ko:K09689,ko:K09691 ko02010,map02010 M00249,M00250,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.101,3.A.1.103 Bacteria 2GIVF@201174,4FMUZ@85023,COG1134@1,COG1134@2 NA|NA|NA GM ATPases associated with a variety of cellular activities MAG.T22.42_01534 1348663.KCH_19980 6e-31 140.6 Kitasatospora ogt GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 ko:K00567 ko00000,ko01000,ko03400 Bacteria 2IFID@201174,2M3G5@2063,COG0350@1,COG0350@2 NA|NA|NA L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated MAG.T22.42_01535 1194165.CAJF01000026_gene3325 2.4e-43 181.8 Microbacteriaceae iscU ko:K04488 ko00000 Bacteria 2IHY9@201174,4FP70@85023,COG0822@1,COG0822@2 NA|NA|NA C NifU-like N terminal domain MAG.T22.42_01536 1449058.JQKT01000015_gene2210 4.3e-167 594.3 Microbacteriaceae sufS GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 Bacteria 2GIVK@201174,4FMA5@85023,COG0520@1,COG0520@2 NA|NA|NA E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine MAG.T22.42_01537 31964.CMS2346 1.6e-07 62.4 Actinobacteria Bacteria 2DS5F@1,2GWNH@201174,33EKY@2 NA|NA|NA S SdpI/YhfL protein family MAG.T22.42_01539 1449058.JQKT01000007_gene876 3.8e-59 236.1 Microbacteriaceae Bacteria 2GU7G@201174,4FKU4@85023,COG1403@1,COG1403@2 NA|NA|NA V Domain of unknown function (DUF222) MAG.T22.42_01540 1120958.AULD01000015_gene1320 2.9e-221 774.6 Microbacteriaceae hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 2GKAQ@201174,4FKWC@85023,COG0286@1,COG0286@2 NA|NA|NA V N-6 DNA Methylase MAG.T22.42_01541 1348338.ADILRU_0468 2.5e-111 408.7 Microbacteriaceae ko:K07341 ko00000,ko02048 Bacteria 2IA5J@201174,4FQY1@85023,COG3654@1,COG3654@2,COG3943@1,COG3943@2 NA|NA|NA S Virulence protein RhuM family MAG.T22.42_01542 525903.Taci_1544 1.1e-84 320.5 Synergistetes 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 3TB76@508458,COG0732@1,COG0732@2 NA|NA|NA L PFAM Type I restriction modification DNA specificity domain MAG.T22.42_01543 196162.Noca_1107 0.0 1242.3 Propionibacteriales hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 2HI69@201174,4DPUS@85009,COG0610@1,COG0610@2 NA|NA|NA V Subunit R is required for both nuclease and ATPase activities, but not for modification MAG.T22.42_01546 1120960.ATXG01000002_gene2940 2.9e-164 585.1 Microbacteriaceae tig GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 ko:K03545 ko00000 Bacteria 2GJIG@201174,4FMK4@85023,COG0544@1,COG0544@2 NA|NA|NA O Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase MAG.T22.42_01547 1121952.ATXT01000011_gene3056 1.1e-98 365.9 Microbacteriaceae clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2GK5C@201174,4FM3B@85023,COG0740@1,COG0740@2 NA|NA|NA OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins MAG.T22.42_01548 1120959.ATXF01000004_gene2609 2.7e-96 358.2 Microbacteriaceae clpP GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2GKNK@201174,4FKH7@85023,COG0740@1,COG0740@2 NA|NA|NA OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins MAG.T22.42_01549 1121372.AULK01000001_gene2254 6e-185 653.7 Microbacteriaceae clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 2GJXQ@201174,4FKD2@85023,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP MAG.T22.42_01550 1001240.GY21_08235 1.7e-96 359.8 Microbacteriaceae ydcO GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K05782 ko00000,ko02000 2.A.46.1 Bacteria 2GNQX@201174,4FM6B@85023,COG3135@1,COG3135@2 NA|NA|NA Q Benzoate membrane transport protein MAG.T22.42_01551 1120960.ATXG01000002_gene2948 2.5e-83 315.8 Microbacteriaceae GO:0008150,GO:0040007 Bacteria 28PUQ@1,2GNQM@201174,2ZCFK@2,4FKYK@85023 NA|NA|NA S Protein of unknown function (DUF3071) MAG.T22.42_01552 1120959.ATXF01000004_gene2614 2.6e-32 144.4 Microbacteriaceae Bacteria 2ATJW@1,2IKN0@201174,31J3Z@2,4FP3C@85023 NA|NA|NA S Domain of unknown function (DUF4193) MAG.T22.42_01553 1389489.O159_11140 1.2e-31 142.9 Microbacteriaceae Bacteria 2E4C2@1,2IFS5@201174,32Z7M@2,4FP4A@85023 NA|NA|NA S Protein of unknown function (DUF3093) MAG.T22.42_01554 1120960.ATXG01000002_gene2951 1.4e-56 225.7 Microbacteriaceae dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2IHYY@201174,4FNR6@85023,COG0756@1,COG0756@2 NA|NA|NA F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA MAG.T22.42_01555 1121372.AULK01000001_gene2121 8.2e-68 263.5 Microbacteriaceae Bacteria 28J4D@1,2GJYC@201174,2Z90C@2,4FMUV@85023 NA|NA|NA S Protein of unknown function (DUF3710) MAG.T22.42_01556 1120960.ATXG01000002_gene2953 4.7e-50 204.9 Microbacteriaceae Bacteria 2AVV0@1,2GJKP@201174,31MNQ@2,4FNXR@85023 NA|NA|NA S Protein of unknown function (DUF3159) MAG.T22.42_01557 1120960.ATXG01000002_gene2954 0.0 1536.5 Microbacteriaceae acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GJD5@201174,4FMPV@85023,COG1048@1,COG1048@2 NA|NA|NA C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate MAG.T22.42_01558 1120960.ATXG01000002_gene2955 1.2e-285 988.8 Microbacteriaceae dxs GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 iEcSMS35_1347.EcSMS35_0456,iIT341.HP0354,iJN746.PP_0527 Bacteria 2GMFA@201174,4FM5E@85023,COG1154@1,COG1154@2 NA|NA|NA HI Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) MAG.T22.42_01559 1121924.ATWH01000006_gene1897 3.6e-310 1070.5 Microbacteriaceae fadB 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ50@201174,4FMJ3@85023,COG1024@1,COG1024@2,COG1250@1,COG1250@2 NA|NA|NA I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain MAG.T22.42_01560 1278308.KB907074_gene697 3.4e-182 644.4 Microbacteriaceae fadA GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2612,iECNA114_1301.ECNA114_4154,iECOK1_1307.ECOK1_4314,iECP_1309.ECP_4058,iECS88_1305.ECS88_4293,iECSF_1327.ECSF_3702,iEcE24377_1341.EcE24377A_4364,iLF82_1304.LF82_0613,iNRG857_1313.NRG857_19195,iPC815.YPO3767 Bacteria 2GJAC@201174,4FKH2@85023,COG0183@1,COG0183@2 NA|NA|NA I Thiolase, C-terminal domain MAG.T22.42_01561 1120959.ATXF01000004_gene2623 4.2e-127 461.5 Microbacteriaceae rnd 3.1.13.5 ko:K03684 ko00000,ko01000,ko03016 Bacteria 2GKNM@201174,4FKQQ@85023,COG0349@1,COG0349@2 NA|NA|NA J 3'-5' exonuclease MAG.T22.42_01562 281090.Lxx10500 9.6e-61 240.0 Microbacteriaceae Bacteria 2AIF4@1,2GK8R@201174,318WM@2,4FKX4@85023 NA|NA|NA S Protein of unknown function (DUF3000) MAG.T22.42_01563 1120959.ATXF01000004_gene2625 3e-82 312.4 Microbacteriaceae 3.1.1.85 ko:K02170,ko:K06889 ko00780,ko01100,map00780,map01100 M00572 R09725 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMK3@201174,4FM70@85023,COG1073@1,COG1073@2 NA|NA|NA S Alpha/beta hydrolase family MAG.T22.42_01564 1120959.ATXF01000004_gene2628 1e-123 449.9 Microbacteriaceae ko:K06916 ko00000,ko03036 Bacteria 2GNQA@201174,4FM37@85023,COG1485@1,COG1485@2 NA|NA|NA S AFG1-like ATPase MAG.T22.42_01565 1121924.ATWH01000006_gene1888 4e-181 641.0 Microbacteriaceae amt ko:K03320 ko00000,ko02000 1.A.11 Bacteria 2GIZK@201174,4FKS4@85023,COG0004@1,COG0004@2 NA|NA|NA P Ammonium Transporter Family MAG.T22.42_01570 1121924.ATWH01000006_gene1882 2.3e-284 984.6 Microbacteriaceae thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GKTC@201174,4FKZJ@85023,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) MAG.T22.42_01571 1151126.AQYI01000004_gene1227 4.6e-73 280.8 Microbacteriaceae hit GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 ko:K19710 ko00230,map00230 R00126,R01618 RC00002,RC02753,RC02795 ko00000,ko00001,ko01000 Bacteria 2GJT5@201174,4FKCF@85023,COG0537@1,COG0537@2 NA|NA|NA FG Protein similar to CwfJ C-terminus 1 MAG.T22.42_01572 1121924.ATWH01000006_gene1880 2.3e-130 471.9 Microbacteriaceae pdxS GO:0003674,GO:0005488,GO:0005515,GO:0042802 4.3.3.6 ko:K06215 ko00750,map00750 R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 Bacteria 2GK1T@201174,4FKED@85023,COG0214@1,COG0214@2 NA|NA|NA H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively MAG.T22.42_01573 1120959.ATXF01000004_gene2637 1.4e-78 299.3 Microbacteriaceae pdxT GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 iHN637.CLJU_RS19495 Bacteria 2GNYG@201174,4FN0E@85023,COG0311@1,COG0311@2 NA|NA|NA H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS MAG.T22.42_01574 1120960.ATXG01000002_gene2975 7.8e-116 423.3 Microbacteriaceae yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 Bacteria 2GJ4G@201174,4FKXU@85023,COG0217@1,COG0217@2 NA|NA|NA K regulation of nucleic acid-templated transcription MAG.T22.42_01575 1121952.ATXT01000011_gene2850 1.2e-57 229.6 Microbacteriaceae ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJI5@201174,4FNJN@85023,COG0817@1,COG0817@2 NA|NA|NA L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group MAG.T22.42_01576 1121372.AULK01000001_gene2092 3.1e-43 181.8 Microbacteriaceae ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GN17@201174,4FNSS@85023,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB MAG.T22.42_01577 1120959.ATXF01000004_gene2643 1.4e-144 519.2 Microbacteriaceae ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJZF@201174,4FMEE@85023,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing MAG.T22.42_01578 1120959.ATXF01000004_gene2644 2.8e-24 117.9 Microbacteriaceae yajC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2HSP5@201174,4FPNG@85023,COG1862@1,COG1862@2 NA|NA|NA U Preprotein translocase subunit MAG.T22.42_01579 1120959.ATXF01000004_gene2645 1.6e-204 719.2 Microbacteriaceae secD GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 Bacteria 2GJTT@201174,4FKDR@85023,COG0342@1,COG0342@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA MAG.T22.42_01580 1120959.ATXF01000004_gene2646 1.1e-114 419.9 Microbacteriaceae secF GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 ko:K03072,ko:K03074,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 Bacteria 2GJRS@201174,4FMNG@85023,COG0341@1,COG0341@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA MAG.T22.42_01581 1120960.ATXG01000002_gene2982 0.0 1215.3 Microbacteriaceae relA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 Bacteria 2GJYQ@201174,4FMKK@85023,COG0317@1,COG0317@2 NA|NA|NA KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance MAG.T22.42_01582 1120959.ATXF01000004_gene2648 9.7e-09 67.0 Microbacteriaceae Bacteria 2DT7K@1,2GSDC@201174,33J1V@2,4FQ2I@85023 NA|NA|NA MAG.T22.42_01583 1121934.AUDX01000010_gene538 2.5e-119 435.6 Microbacteriaceae 3.1.26.12,3.2.1.8 ko:K01181,ko:K08300,ko:K08301 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 2I2EC@201174,4FK51@85023,COG3266@1,COG3266@2 NA|NA|NA S Domain of Unknown Function (DUF349) MAG.T22.42_01584 1121924.ATWH01000006_gene1867 9.6e-74 283.5 Microbacteriaceae ppiB 5.2.1.8 ko:K01802,ko:K03768 ko00000,ko01000,ko03110 Bacteria 2GN8G@201174,4FMTW@85023,COG0652@1,COG0652@2 NA|NA|NA O Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MAG.T22.42_01585 1121372.AULK01000001_gene2083 1.8e-163 582.4 Microbacteriaceae rarA ko:K07478 ko00000 Bacteria 2GKDP@201174,4FKCI@85023,COG2256@1,COG2256@2 NA|NA|NA L MgsA AAA+ ATPase C terminal MAG.T22.42_01586 1177594.MIC448_350009 2.7e-98 364.8 Microbacteriaceae rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GIRX@201174,4FK7X@85023,COG0522@1,COG0522@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit MAG.T22.42_01587 1151122.AQYD01000005_gene3219 1.5e-25 122.1 Microbacteriaceae Bacteria 2BM5Q@1,2H07V@201174,32FPB@2,4FQSH@85023 NA|NA|NA MAG.T22.42_01588 546268.NEISUBOT_04315 4.1e-07 62.4 Proteobacteria Bacteria 1N8AW@1224,2CGJK@1,333WW@2 NA|NA|NA # 1455 queries scanned # Total time (seconds): 3.07814311981 # Rate: 472.69 q/s